GO:0006696

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Name ergosterol biosynthetic process
Categary Process
Go Slim No
Go Link GO:0006696
Unique Molecular Interactions 44
Total Molecular Interactions 53
Total Single Events 439
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ergosterol biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for ergosterol biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
2 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
3 INT110542 SIGMAR1 Regulation of OPRM1 1 0.04 0.33 1.25
4 INT110543 SIGMAR1 Regulation of Gene_expression of OPRM1 1 0.04 0.33 1.25
5 INT76256 Binding of Slc6a3 and Sigmar1 1 0.20 0 1.16
6 INT151218 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.26 1.03
7 INT107335 Pdpk1 Positive_regulation of Regulation of Sigmar1 1 0.02 0 0.93
8 INT167767 Prkcz Positive_regulation of Phosphorylation of Sigmar1 1 0.04 0.23 0.9
9 INT167766 Prkcz Positive_regulation of Positive_regulation of Sigmar1 1 0.04 0.23 0.9
10 INT167771 Prkca Positive_regulation of Phosphorylation of Sigmar1 1 0.38 0.23 0.89
11 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 0.15 0 0.87
12 INT167770 Sigmar1 Positive_regulation of Prkcz 1 0.04 0.34 0.77
13 INT167768 Regulation of Sigmar1 Positive_regulation of Prkcz 1 0.02 0.34 0.77
14 INT106691 Ngf Positive_regulation of SIGMAR1 1 0.04 0 0.74
15 INT65426 Sigmar1 Regulation of Gpi1 1 0.21 0 0.7
16 INT55919 Binding of Sigmar1 and Ap2s1 1 0.02 0.84 0.6
17 INT95895 Sigmar1 Regulation of Positive_regulation of Npy 1 0.18 0 0.55
18 INT21372 Binding of pcp and Sigmar1 1 0.01 0 0.53
19 INT151220 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Prkca 1 0.00 0.13 0.51
20 INT151222 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Adrbk1 1 0.00 0.13 0.51
21 INT151223 Negative_regulation of SIGMAR1 Negative_regulation of Adrbk1 1 0.00 0.13 0.51
22 INT151219 Negative_regulation of SIGMAR1 Negative_regulation of Prkca 1 0.00 0.13 0.51
23 INT151221 Negative_regulation of SIGMAR1 Negative_regulation of Akt1 1 0.00 0.13 0.51
24 INT12453 Sigmar1 Regulation of Gene_expression of Penk 2 0.35 0 0.43
25 INT224584 Binding of IL1RN and SIGMAR1 1 0.00 0.73 0.36
26 INT194865 Binding of SIGMAR1 and Positive_regulation of IL1B 1 0.01 0.62 0.35
27 INT194862 SIGMAR1 Positive_regulation of IL1B 1 0.01 0.62 0.35
28 INT28327 Binding of Sigmar1 and Abat 1 0.15 0.14 0.35
29 INT214987 Binding of FANCC and Sigmar1 1 0.06 0.34 0.32
30 INT194858 Binding of IL1B and SIGMAR1 1 0.01 0.55 0.3
31 INT158621 Binding of SIGMAR1 and Sphk1 1 0.01 0 0.25
32 INT214977 Binding of Jun and Sigmar1 1 0.01 0.27 0.24
33 INT136492 Binding of Adarb1 and Sigmar1 1 0.03 0.1 0.21
34 INT72325 Binding of Sigmar1 and WWOX 1 0.26 0 0.18
35 INT18043 Binding of SIGMAR1 and Pgr 1 0.00 0.06 0.16
36 INT214978 Positive_regulation of Sigmar1 Positive_regulation of Positive_regulation of Fosl2 1 0.01 0.23 0.16
37 INT145207 Binding of Sigmar1 and Ctdspl2 1 0.00 0 0.12
38 INT145214 Binding of Sigmar1 and Herc1 1 0.00 0 0.11
39 INT66109 SIGMAR1 Regulation of Localization of Pomc 1 0.00 0 0.1
40 INT102636 Binding of Sigmar1 and Mir377 1 0.05 0.19 0.07
41 INT211347 Binding of Sigmar1 and Positive_regulation of Casp3 1 0.12 0.92 0.06
42 INT252823 Binding of TNF and SIGMAR1 1 0.01 0.95 0.05
43 INT214980 Binding of Cav2 and Sigmar1 1 0.02 0.07 0
44 INT209986 Binding of HSD11B1 and SIGMAR1 1 0.00 0.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for ergosterol biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in ergosterol biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT12837 Binding of SIGMAR1 57 0.48 5.31 15.49
2 INT20715 Binding of Sigmar1 45 0.48 4.03 13.17
3 INT13338 Regulation of Sigmar1 22 0.57 2.91 11.35
4 INT60148 Regulation of Sigmar1 20 0.43 7.23 7.76
5 INT12838 Gene_expression of SIGMAR1 30 0.78 3.52 6.81
6 INT25242 Positive_regulation of Sigmar1 17 0.66 3.93 5.65
7 INT55917 Binding of Sigmar1 26 0.45 12.65 5.58
8 INT5978 Positive_regulation of SIGMAR1 13 0.42 0.72 5.35
9 INT140142 Positive_regulation of Sigmar1 17 0.63 3.78 5.26
10 INT64668 Regulation of SIGMAR1 13 0.60 0.54 3.91
11 INT72290 Localization of Sigmar1 21 0.74 4.35 3.54
12 INT114571 Gene_expression of Sigmar1 39 0.77 36.78 3.4
13 INT29064 Gene_expression of Sigmar1 9 0.77 2.48 2.65
14 INT40479 Negative_regulation of SIGMAR1 6 0.52 1.26 1.88
15 INT107332 Negative_regulation of Regulation of Sigmar1 1 0.19 0 1.86
16 INT61890 Localization of SIGMAR1 6 0.40 0.3 1.52
17 INT25241 Negative_regulation of Sigmar1 10 0.56 2.97 1.5
18 INT26153 Localization of Sigmar1 4 0.80 0.1 1.26
19 INT106690 Positive_regulation of Gene_expression of SIGMAR1 5 0.61 0.12 1.03
20 INT70604 Positive_regulation of Positive_regulation of Sigmar1 2 0.50 0 0.98
21 INT26326 Regulation of Binding of Sigmar1 4 0.27 0.66 0.9
22 INT107333 Regulation of Regulation of Sigmar1 1 0.27 0 0.9
23 INT167761 Phosphorylation of Sigmar1 1 0.46 0.22 0.88
24 INT167762 Positive_regulation of Phosphorylation of Sigmar1 1 0.34 0.22 0.88
25 INT151217 Phosphorylation of SIGMAR1 2 0.04 0.41 0.72
26 INT167760 Positive_regulation of Positive_regulation of Sigmar1 2 0.32 0.42 0.68
27 INT103199 Positive_regulation of Positive_regulation of SIGMAR1 2 0.13 0.15 0.62
28 INT63458 Negative_regulation of Binding of Sigmar1 2 0.36 0.39 0.52
29 INT110278 Negative_regulation of Sigmar1 3 0.32 0.35 0.47
30 INT90553 Positive_regulation of Regulation of Sigmar1 1 0.39 0 0.41
31 INT61891 Positive_regulation of Binding of SIGMAR1 2 0.32 0.34 0.39
32 INT214974 Positive_regulation of Gene_expression of Sigmar1 2 0.52 1.92 0.38
33 INT214965 Positive_regulation of Localization of Sigmar1 1 0.44 0.42 0.31
34 INT63457 Positive_regulation of Gene_expression of Sigmar1 1 0.36 0.09 0.23
35 INT110279 Regulation of Localization of Sigmar1 1 0.01 0 0.21
36 INT214971 Protein_catabolism of Sigmar1 1 0.56 0.45 0.16
37 INT59959 Positive_regulation of Binding of Sigmar1 1 0.47 0.16 0.14
38 INT18042 Negative_regulation of Binding of SIGMAR1 1 0.12 0 0.13
39 INT211344 Regulation of Binding of Sigmar1 2 0.41 0.65 0.1
40 INT266951 Negative_regulation of Binding of Sigmar1 1 0.32 0.48 0.1
41 INT66203 Regulation of Binding of SIGMAR1 1 0.44 0.19 0.09
42 INT84943 Regulation of Transcription of SIGMAR1 1 0.03 0.08 0.08
43 INT84942 Transcription of SIGMAR1 1 0.06 0.08 0.08
44 INT155520 Regulation of Gene_expression of SIGMAR1 1 0.24 0.16 0
45 INT77301 Positive_regulation of Regulation of Sigmar1 1 0.43 0 0
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