GO:0006701

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Name progesterone biosynthetic process
Categary Process
Go Slim No
Go Link GO:0006701
Unique Molecular Interactions 46
Total Molecular Interactions 57
Total Single Events 478
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for progesterone biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for progesterone biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
2 INT122350 Ngf Regulation of Hsd3b1 1 0.34 0 0.87
3 INT346133 RAMP2 Regulation of ADM 1 0.13 2.06 0.78
4 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
5 INT60538 Gnrh1 Positive_regulation of Localization of LHB 1 0.00 0.19 0.59
6 INT23486 HBE1 Positive_regulation of Localization of FSHB 1 0.03 0 0.54
7 INT23483 HBE1 Positive_regulation of FSHB 1 0.01 0 0.53
8 INT346146 ADM Positive_regulation of Gene_expression of PERP 1 0.02 1.54 0.51
9 INT141964 Binding of ADM and RAMP1 1 0.30 2.63 0.47
10 INT76153 Binding of NCOR2 and Negative_regulation of Localization of LHB 1 0.00 0 0.42
11 INT346151 Binding of ADM and GPER 1 0.01 0.99 0.41
12 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
13 INT346150 Binding of ADM and FN1 1 0.10 0.93 0.39
14 INT346140 Positive_regulation of Binding of ADM and MMRN1 1 0.04 0.93 0.39
15 INT346139 Binding of ADM and MMRN1 1 0.03 0.93 0.39
16 INT346135 Positive_regulation of Binding of ADM and FN1 1 0.13 0.93 0.39
17 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
18 INT346145 Binding of ADM and TPX2 1 0.01 1.05 0.35
19 INT89895 LHB Positive_regulation of Localization of PRL 1 0.09 0 0.29
20 INT89901 LHB Positive_regulation of Localization of GH1 1 0.03 0 0.29
21 INT89913 LHB Positive_regulation of Localization of POMC 1 0.10 0 0.29
22 INT85011 ADM Regulation of CALCRL 1 0.06 0 0.24
23 INT346134 ADM Regulation of Gene_expression of MMRN1 1 0.04 1.29 0.23
24 INT346143 ADM Regulation of Gene_expression of TPX2 1 0.02 1.29 0.23
25 INT35161 FSHR Regulation of LHB 1 0.18 0 0.21
26 INT35150 PLOD1 Regulation of LHB 1 0.09 0 0.21
27 INT35158 GH1 Regulation of LHB 1 0.08 0 0.21
28 INT172254 Binding of ADM and TAS2R14 1 0.02 0 0.17
29 INT12524 Binding of LHB and POMC 1 0.12 1.96 0.17
30 INT172245 Binding of ADM and NCOR2 1 0.01 0 0.15
31 INT172236 Binding of ADM and APLNR 1 0.06 0 0.14
32 INT72029 Binding of ADM and IAPP 1 0.12 0.26 0.13
33 INT116450 POMC Negative_regulation of Localization of LHB 1 0.08 0 0.1
34 INT12523 Binding of FSHR and LHB 1 0.11 0.98 0.09
35 INT346136 ADM Positive_regulation of ICAM1 1 0.20 0.92 0.08
36 INT100127 ADM Positive_regulation of PRL 1 0.28 0.51 0.08
37 INT346147 ADM Positive_regulation of Gene_expression of VCAM1 1 0.19 0.91 0.08
38 INT346149 ADM Positive_regulation of Gene_expression of SELE 1 0.22 0.85 0.07
39 INT207700 ADM Regulation of MSMB 1 0.18 0.69 0.04
40 INT259451 Binding of DHCR7 and Cyp11a1 1 0.01 0.3 0
41 INT225085 Binding of ADM and Negative_regulation of LEP 1 0.16 1.04 0
42 INT244690 FSHB Positive_regulation of KDSR 1 0.00 0 0
43 INT242178 CYP19A1 Regulation of Cyp11a1 1 0.01 0.35 0
44 INT242179 Cyp11a1 Regulation of CYP19A1 1 0.01 0.7 0
45 INT259452 Binding of STAR and Cyp11a1 1 0.25 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for progesterone biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in progesterone biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5372 Localization of LHB 55 0.68 9.47 19
2 INT9946 Regulation of Localization of LHB 27 0.52 2.47 11.08
3 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
4 INT1648 Regulation of LHB 21 0.61 3.32 9.6
5 INT9729 Negative_regulation of LHB 14 0.42 1.86 4.63
6 INT11370 Positive_regulation of LHB 15 0.28 5.45 4.01
7 INT112340 Gene_expression of Cyp11a1 11 0.77 5.19 3.7
8 INT31580 Negative_regulation of Cyp11a1 14 0.57 3.48 3.61
9 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01
10 INT11371 Positive_regulation of Localization of LHB 8 0.47 1.4 2.93
11 INT16015 Negative_regulation of Localization of LHB 10 0.37 2.95 2.9
12 INT4147 Gene_expression of LHB 8 0.49 3.94 2.88
13 INT15606 Localization of FSHB 24 0.78 9.16 2.49
14 INT15604 Gene_expression of FSHB 30 0.56 9.7 2.45
15 INT250727 Negative_regulation of ADM 3 0.38 8.32 2.26
16 INT141968 Positive_regulation of ADM 12 0.65 11.19 2
17 INT23491 Positive_regulation of FSHB 14 0.65 7.2 1.79
18 INT122346 Gene_expression of Hsd3b1 1 0.75 0 1.78
19 INT102449 Binding of ADM 12 0.33 5.85 1.73
20 INT112339 Localization of Cyp11a1 2 0.71 0.94 1.68
21 INT10570 Positive_regulation of Cyp11a1 9 0.47 2.67 1.4
22 INT122345 Positive_regulation of Gene_expression of Hsd3b1 1 0.49 0 1.34
23 INT252389 Negative_regulation of Gene_expression of ADM 2 0.38 4.78 1.3
24 INT141969 Positive_regulation of Gene_expression of ADM 4 0.57 4.07 1.2
25 INT9730 Binding of LHB 4 0.35 2.38 1.19
26 INT23495 Positive_regulation of Localization of FSHB 7 0.40 0.4 1.07
27 INT122347 Transcription of Hsd3b1 1 0.52 0 0.99
28 INT10578 Transcription of Cyp11a1 3 0.53 0.84 0.93
29 INT225094 Localization of ADM 5 0.63 3.89 0.91
30 INT23492 Negative_regulation of Localization of FSHB 2 0.42 0.73 0.66
31 INT32612 Negative_regulation of FSHB 3 0.41 2.17 0.58
32 INT29619 Negative_regulation of Gene_expression of FSHB 5 0.05 0.59 0.57
33 INT27728 Negative_regulation of Gene_expression of LHB 2 0.04 1.59 0.53
34 INT27729 Negative_regulation of Regulation of LHB 1 0.02 0.44 0.53
35 INT346181 Regulation of Gene_expression of ADM 1 0.35 1.67 0.52
36 INT122348 Regulation of Hsd3b1 1 0.60 0 0.46
37 INT68725 Regulation of Cyp11a1 6 0.19 2.62 0.44
38 INT121113 Protein_catabolism of Cyp11a1 2 0.65 0.37 0.44
39 INT72196 Transcription of LHB 1 0.02 0.28 0.43
40 INT17581 Regulation of Regulation of LHB 1 0.01 0 0.43
41 INT207726 Regulation of ADM 4 0.40 2.14 0.42
42 INT112327 Positive_regulation of Gene_expression of FSHB 5 0.44 3.64 0.39
43 INT346173 Negative_regulation of Positive_regulation of ADM 1 0.38 1.02 0.39
44 INT117760 Regulation of Gene_expression of Cyp11a1 2 0.42 0.36 0.25
45 INT102450 Positive_regulation of Binding of ADM 1 0.29 0 0.24
46 INT97578 Regulation of FSHB 3 0.26 1.41 0.17
47 INT10575 Positive_regulation of Transcription of Cyp11a1 1 0.05 0 0.17
48 INT10572 Positive_regulation of Positive_regulation of Cyp11a1 1 0.05 0 0.16
49 INT97577 Regulation of Localization of FSHB 1 0.59 0.79 0.13
50 INT228064 Positive_regulation of Positive_regulation of FSHB 2 0.29 0.84 0.05
51 INT140315 Regulation of Positive_regulation of Cyp11a1 1 0.19 0.07 0.05
52 INT226090 Negative_regulation of Binding of LHB 1 0.10 0.06 0.04
53 INT252388 Transcription of ADM 1 0.03 0 0.04
54 INT225092 Positive_regulation of Localization of ADM 1 0.29 0.06 0
55 INT176566 Protein_catabolism of LHB 1 0.02 0.13 0
56 INT259446 Positive_regulation of Gene_expression of Cyp11a1 1 0.28 0 0
57 INT243479 Phosphorylation of FSHB 1 0.17 1.43 0
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