GO:0006707

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Name cholesterol catabolic process
Categary Process
Go Slim No
Go Link GO:0006707
Unique Molecular Interactions 241
Total Molecular Interactions 334
Total Single Events 2555
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cholesterol catabolic process. They are ordered first by their pain relevance and then by number of times they were reported for cholesterol catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT33756 Akr1d1 Positive_regulation of Npr1 3 0.01 0 2.05
2 INT33759 Hmmr Positive_regulation of Akr1d1 1 0.00 0 1.58
3 INT7791 Akr1d1 Regulation of Nts 1 0.03 0 1.58
4 INT7796 Akr1d1 Regulation of Npy 1 0.03 0 1.57
5 INT7797 Akr1d1 Regulation of Sst 1 0.02 0 1.54
6 INT219686 Binding of CEL and COPD 1 0.12 11.35 1.26
7 INT81097 Akr1d1 Regulation of Localization of Abat 1 0.00 0 1.2
8 INT13203 Oprd1 Negative_regulation of Akr1d1 1 0.01 0 1.18
9 INT13204 Binding of Npr1 and Akr1d1 1 0.00 0 1.14
10 INT76199 CASP1 Positive_regulation of CEL 1 0.06 0.32 1.14
11 INT97721 Akr1d1 Regulation of Gene_expression of Penk 1 0.00 0 0.98
12 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
13 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
14 INT80601 Akr1d1 Regulation of Positive_regulation of Fos 1 0.06 0 0.94
15 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
16 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
17 INT7799 Akr1d1 Regulation of Positive_regulation of Ptgdr 1 0.01 0 0.86
18 INT261461 Positive_regulation of Akr1d1 Regulation of Sftpd 1 0.01 0 0.86
19 INT261458 Akr1d1 Regulation of Sftpd 1 0.01 0 0.82
20 INT99578 Binding of CEL and Kit 1 0.04 1.07 0.81
21 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
22 INT261447 Sftpd Positive_regulation of Akr1d1 1 0.01 0 0.77
23 INT82039 Akr1d1 Positive_regulation of Phosphorylation of Ppp1r1b 1 0.02 0 0.74
24 INT95148 CEL Regulation of IL1B 1 0.24 0.88 0.7
25 INT7792 Akr1d1 Regulation of Gene_expression of Npy 1 0.02 0 0.65
26 INT261453 Binding of Akr1d1 and Ptgdr 1 0.00 0.56 0.65
27 INT82038 Positive_regulation of Akr1d1 Positive_regulation of Phosphorylation of Ppp1r1b 1 0.02 0 0.64
28 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
29 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
30 INT63161 Akr1d1 Regulation of Gene_expression of Pdyn 1 0.01 0 0.59
31 INT26648 Binding of CEL and HP 1 0.04 0 0.58
32 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
33 INT54485 Positive_regulation of Akr1d1 Positive_regulation of Gene_expression of Rabep2 1 0.00 0 0.53
34 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
35 INT20580 Drd2 Regulation of Akr1d1 1 0.02 0.26 0.51
36 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
37 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
38 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
39 INT160444 Tpsab1 Positive_regulation of Gene_expression of CEL 1 0.48 0.96 0.48
40 INT7291 Akr1d1 Regulation of Regulation of Penk 1 0.01 0 0.48
41 INT195192 Akr1d1 Regulation of Msn 1 0.01 0.34 0.47
42 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
43 INT136749 COX5A Positive_regulation of Gene_expression of SCARB1 1 0.52 0.36 0.45
44 INT262155 Nr5a2 Positive_regulation of Cyp7a1 1 0.07 0.24 0.45
45 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
46 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43
47 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
48 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
49 INT262186 Nr0b2 Positive_regulation of Negative_regulation of Cyp7a1 1 0.12 0.28 0.4
50 INT219683 Binding of CEL and GOPC 1 0.04 3.11 0.38
51 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36
52 INT261462 Akr1d1 Positive_regulation of Hrasls 1 0.00 0.3 0.33
53 INT17162 Binding of CEL and Lhb 1 0.06 0.38 0.3
54 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
55 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
56 INT51858 Akr1d1 Positive_regulation of Phosphorylation of Creb1 1 0.01 0 0.27
57 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
58 INT213029 Positive_regulation of Binding of Apoa1 and Scarb1 1 0.09 3.38 0.27
59 INT64290 Akr1d1 Regulation of Penk 1 0.00 0 0.26
60 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
61 INT186191 Binding of SCARB1 and TBP 1 0.03 2.57 0.24
62 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
63 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
64 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
65 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
66 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
67 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
68 INT335015 Fgf15 Negative_regulation of Gene_expression of Cyp7a1 1 0.57 0.2 0.24
69 INT262211 Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23
70 INT262159 Positive_regulation of Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23
71 INT64291 Akr1d1 Regulation of Slc3a1 1 0.01 0 0.23
72 INT64289 Slc3a1 Regulation of Akr1d1 1 0.01 0 0.23
73 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
74 INT106993 CEL Positive_regulation of NR1I2 1 0.39 0.39 0.22
75 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
76 INT49057 Positive_regulation of CEL Positive_regulation of Localization of LTC4S 1 0.41 0.28 0.18
77 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
78 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
79 INT122528 Apoe Regulation of Eno2 1 0.05 0.29 0.16
80 INT229289 FGF19 Negative_regulation of CYP7A1 1 0.26 0.32 0.16
81 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16
82 INT261460 Binding of Sftpd and Akr1d1 1 0.01 0.43 0.16
83 INT297345 Apoe Negative_regulation of Csf2 1 0.17 0.66 0.16
84 INT231838 Pcdh8 Regulation of Cel 1 0.00 0.39 0.15
85 INT85816 Binding of CEL and TTR 1 0.39 0.77 0.14
86 INT231846 Pcdh8 Negative_regulation of Positive_regulation of Cel 1 0.00 0.91 0.14
87 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14
88 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14
89 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14
90 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13
91 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12
92 INT173121 PPARA Negative_regulation of Gene_expression of CYP7A1 1 0.18 0.48 0.12
93 INT92671 Binding of CEL and HLA-B 1 0.38 0.19 0.1
94 INT208361 Positive_regulation of Binding of Apoe and Hdl1 1 0.12 1.22 0.1
95 INT246535 Binding of Cel and Mag 1 0.01 7.26 0.1
96 INT297346 Apoe Negative_regulation of Localization of TNF 1 0.48 0.26 0.1
97 INT32030 Binding of CEL and ERLEC1 1 0.08 0.42 0.1
98 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
99 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07
100 INT297330 Apoe Positive_regulation of Gene_expression of Nos2 1 0.26 0.34 0.07
101 INT308665 Binding of Apoe and Gopc 1 0.02 0.49 0.07
102 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07
103 INT50078 Binding of APOE and NPPA 1 0.30 0.42 0.07
104 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
105 INT261454 Akr1d1 Regulation of Drd1a 1 0.00 0.71 0.06
106 INT186188 Binding of SCARB1 and PDZK1 1 0.53 0.54 0.05
107 INT186185 Binding of SCARB1 and SCARB2 1 0.22 0.58 0.05
108 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05
109 INT231834 Trip12 Positive_regulation of Positive_regulation of Cel 1 0.00 0.75 0.05
110 INT133047 TNF Positive_regulation of Gene_expression of CEL 1 0.47 0.61 0.05
111 INT177350 Binding of CEL and PLA2G2A 1 0.06 0.08 0.04
112 INT208356 Hdl1 Positive_regulation of Apoe 1 0.12 1.25 0.04
113 INT186187 LDLR Regulation of Gene_expression of SCARB1 1 0.17 1.71 0.04
114 INT235551 Gene_expression of Hras1 Negative_regulation of Positive_regulation of Apoe 1 0.03 0.57 0.04
115 INT208357 Hdl1 Positive_regulation of Localization of Apoe 1 0.12 1.26 0.04
116 INT208350 Positive_regulation of Hdl1 Positive_regulation of Apoe 1 0.12 1.27 0.04
117 INT290181 Binding of APOE and PLTP 1 0.17 1.61 0.04
118 INT225027 Binding of TAPBP and TRERF1 1 0.33 0 0.04
119 INT290375 Binding of Scarb1 and Gopc 1 0.15 0.29 0.04
120 INT213002 Binding of Scarb1 and Trib3 1 0.00 1.02 0.03
121 INT194483 Binding of Apoe and Chol1 1 0.24 0.51 0.03
122 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
123 INT213011 Binding of Scarb1 and Hdl1 1 0.13 0.96 0.03
124 INT177352 Binding of CEL and PTN 1 0.01 0 0.03
125 INT208352 Apoe Regulation of Localization of Em 1 0.04 1.15 0.03
126 INT186186 LDLR Regulation of SCARB1 1 0.08 0.65 0.03
127 INT194481 Binding of Apoe and Apob 1 0.07 0.51 0.03
128 INT308658 Binding of Apoa2 and Apoe 1 0.17 0.15 0.03
129 INT247155 Binding of Phb2 and Scarb1 1 0.01 0.33 0
130 INT186190 OLR1 Positive_regulation of SCARB1 1 0.01 0.67 0
131 INT341487 Binding of APOE and TLR2 1 0.00 0.3 0
132 INT326065 APOE Positive_regulation of LCAT 1 0.53 0.84 0
133 INT209987 Binding of APOE and LDLR 1 0.24 0 0
134 INT208349 Regulation of Binding of Apoc3 and Apoe 1 0.01 0.38 0
135 INT260519 Binding of Prnp and Scarb1 1 0.41 0.21 0
136 INT352625 Trp53 Regulation of CEL 1 0.00 0.71 0
137 INT290374 Binding of Scarb1 and Ncapg2 1 0.23 0.43 0
138 INT304135 Binding of CEL and Positive_regulation of CASP8 1 0.00 0.52 0
139 INT90283 Binding of APOE and Il1a 1 0.01 0 0
140 INT260520 Binding of Myc and Scarb1 1 0.33 0.16 0
141 INT201080 Binding of APOE and HLA-C 1 0.41 0.31 0
142 INT353802 Binding of APOE and Apob 1 0.05 0.83 0
143 INT208355 Binding of Apoc3 and Apoe 1 0.01 0.76 0
144 INT198933 Binding of Apoe and App 1 0.33 0.19 0
145 INT186189 LDLR Positive_regulation of Gene_expression of SCARB1 1 0.14 1.27 0
146 INT290373 Binding of Cd36 and Scarb1 1 0.11 0 0
147 INT353801 Binding of APOE and Cd320 1 0.22 0.83 0
148 INT44885 Binding of CEL and MET 1 0.39 0.15 0
149 INT250152 Binding of APOE and UBE4B 1 0.21 1.2 0
150 INT326059 APOA1 Positive_regulation of Gene_expression of APOE 1 0.61 0.38 0
151 INT213043 Regulation of Binding of Apoa1 and Scarb1 1 0.05 1.12 0
152 INT246536 Mag Regulation of Gene_expression of Cel 1 0.01 1.28 0
153 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0
154 INT326057 APOA1 Regulation of Localization of APOE 1 0.54 1.36 0
155 INT290372 Binding of Ngfr and Scarb1 1 0.01 0.48 0
156 INT201082 Binding of APOE and HLA-B 1 0.54 1.54 0
157 INT284093 VWF Negative_regulation of APOE 1 0.40 2.32 0
158 INT304270 Binding of Apoa1 and Scarb1 1 0.00 0.39 0
159 INT312769 Binding of Apoe and Pon1 1 0.04 0.86 0
160 INT353803 Binding of APOE and Hdl1 1 0.01 0.83 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cholesterol catabolic process. They are ordered first by their pain relevance and then by number of times they were reported in cholesterol catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7787 Positive_regulation of Akr1d1 52 0.66 3.55 31.71
2 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
3 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58
4 INT20575 Gene_expression of Akr1d1 48 0.57 6.2 22.5
5 INT7920 Binding of Akr1d1 26 0.27 3.64 19.73
6 INT34569 Regulation of Akr1d1 26 0.24 3.06 18.37
7 INT11034 Negative_regulation of Akr1d1 23 0.18 3.43 14.84
8 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87
9 INT2241 Negative_regulation of CEL 56 0.58 29.32 8.83
10 INT20579 Transcription of Akr1d1 9 0.04 2.91 8.37
11 INT197493 Localization of Apoe 61 0.79 27.48 7.06
12 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
13 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
14 INT63042 Binding of Apoe 59 0.48 31.23 5.88
15 INT50572 Localization of Akr1d1 14 0.59 0.51 5.87
16 INT23245 Positive_regulation of Gene_expression of CEL 19 0.69 14.81 4.92
17 INT136754 Gene_expression of SCARB1 64 0.77 43.28 4.82
18 INT26754 Positive_regulation of Positive_regulation of Akr1d1 8 0.05 0.28 4.75
19 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
20 INT18995 Binding of CEL 23 0.47 14.46 4.5
21 INT4464 Localization of CEL 21 0.80 8.09 3.88
22 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
23 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
24 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
25 INT175442 Gene_expression of Cel 22 0.34 21.36 3.33
26 INT122511 Negative_regulation of Binding of Akr1d1 1 0.04 0.14 3.29
27 INT72141 Binding of Apoe 11 0.37 10.91 3.27
28 INT97710 Localization of Apoe 1 0.79 7.18 3.2
29 INT53813 Positive_regulation of Cel 20 0.58 19.39 3.05
30 INT50080 Binding of APOE 38 0.45 29.61 2.67
31 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
32 INT176205 Gene_expression of Cyp7a1 8 0.69 2.5 2.45
33 INT50571 Regulation of Gene_expression of Akr1d1 3 0.33 0.33 2.4
34 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
35 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
36 INT20578 Positive_regulation of Gene_expression of Akr1d1 5 0.22 0.26 2.1
37 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
38 INT47628 Regulation of CEL 9 0.60 4.5 1.85
39 INT136752 Positive_regulation of Gene_expression of SCARB1 5 0.69 10.63 1.76
40 INT35937 Negative_regulation of Positive_regulation of Akr1d1 2 0.40 0 1.72
41 INT73616 Positive_regulation of Localization of Akr1d1 2 0.07 0 1.68
42 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
43 INT262117 Negative_regulation of Gene_expression of Cyp7a1 3 0.25 0.91 1.6
44 INT75694 Regulation of Gene_expression of CEL 9 0.60 6.08 1.53
45 INT61553 Positive_regulation of Regulation of Akr1d1 1 0.05 0 1.46
46 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
47 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
48 INT11415 Negative_regulation of Cel 5 0.38 5.67 1.29
49 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
50 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
51 INT20576 Negative_regulation of Gene_expression of Akr1d1 2 0.03 0.23 1.13
52 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
53 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
54 INT211557 Gene_expression of Scarb1 30 0.75 5.03 0.94
55 INT334977 Regulation of Gene_expression of Cyp7a1 2 0.40 0.43 0.94
56 INT82533 Regulation of Positive_regulation of Akr1d1 1 0.08 0 0.94
57 INT294479 Gene_expression of Scarb1 1 0.02 3.08 0.9
58 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8
59 INT136753 Regulation of Gene_expression of SCARB1 2 0.60 7.79 0.77
60 INT322101 Localization of Cel 2 0.29 1.11 0.76
61 INT54353 Regulation of Transcription of Akr1d1 1 0.03 0.08 0.74
62 INT197495 Negative_regulation of Localization of Apoe 6 0.43 2.19 0.73
63 INT81622 Positive_regulation of Positive_regulation of CEL 4 0.49 3.94 0.73
64 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72
65 INT136751 Negative_regulation of SCARB1 6 0.43 2.65 0.7
66 INT76127 Transcription of CEL 5 0.71 2.02 0.7
67 INT197010 Positive_regulation of CYP7A1 4 0.47 1.75 0.7
68 INT229326 Negative_regulation of CYP7A1 3 0.29 1.03 0.7
69 INT270428 Negative_regulation of Binding of APOE 2 0.41 1.16 0.7
70 INT113335 Regulation of Transcription of Apoe 1 0.27 0.51 0.7
71 INT175450 Positive_regulation of Gene_expression of Cel 4 0.25 2.69 0.68
72 INT20577 Negative_regulation of Transcription of Akr1d1 1 0.02 0.23 0.66
73 INT175580 Localization of APOE 10 0.76 18.84 0.65
74 INT93879 Positive_regulation of TRERF1 2 0.61 2.09 0.64
75 INT108328 Negative_regulation of Gene_expression of CEL 6 0.57 2.56 0.63
76 INT136755 Negative_regulation of Gene_expression of SCARB1 2 0.57 6.61 0.63
77 INT97708 Regulation of Localization of Apoe 1 0.61 2.06 0.62
78 INT212959 Binding of Scarb1 12 0.35 7.7 0.61
79 INT183163 Positive_regulation of Positive_regulation of Cel 9 0.31 11.55 0.58
80 INT169489 Positive_regulation of Localization of CEL 1 0.45 0.34 0.58
81 INT231823 Negative_regulation of Positive_regulation of Cel 2 0.17 2.34 0.56
82 INT113334 Positive_regulation of Positive_regulation of Apoe 1 0.50 0.6 0.56
83 INT262093 Positive_regulation of Gene_expression of Cyp7a1 2 0.44 0.81 0.55
84 INT197322 Protein_catabolism of Apoe 6 0.71 3.52 0.51
85 INT217370 Phosphorylation of Apoe 2 0.63 1.8 0.49
86 INT61552 Regulation of Binding of Akr1d1 1 0.06 0 0.49
87 INT136757 Regulation of SCARB1 4 0.27 1.96 0.48
88 INT329888 Positive_regulation of Transcription of CYP7A1 1 0.20 0.9 0.46
89 INT96816 Regulation of APOE 8 0.45 6.62 0.44
90 INT53811 Regulation of Cel 4 0.23 2.1 0.43
91 INT229307 Positive_regulation of Negative_regulation of CYP7A1 1 0.31 0.1 0.43
92 INT228731 Negative_regulation of Gene_expression of Cel 2 0.17 1.12 0.41
93 INT60601 Negative_regulation of Negative_regulation of CEL 1 0.41 0.34 0.4
94 INT97712 Negative_regulation of Transcription of Apoe 1 0.43 1.05 0.4
95 INT176186 Negative_regulation of Cyp7a1 5 0.46 2.07 0.39
96 INT34570 Regulation of Regulation of Akr1d1 1 0.01 0 0.35
97 INT135069 Regulation of Localization of CEL 1 0.44 0 0.34
98 INT131542 Negative_regulation of Gene_expression of APOE 6 0.40 3.92 0.33
99 INT16855 Binding of Scarb1 1 0.21 0 0.33
100 INT16856 Positive_regulation of Binding of Scarb1 1 0.27 0 0.33
101 INT176170 Regulation of Cyp7a1 2 0.21 0.5 0.32
102 INT335088 Regulation of Regulation of Cyp7a1 1 0.19 0.1 0.32
103 INT176200 Positive_regulation of Cyp7a1 2 0.37 0.4 0.31
104 INT352167 Negative_regulation of Positive_regulation of CEL 1 0.04 1.07 0.31
105 INT59862 Phosphorylation of CEL 2 0.70 0.53 0.3
106 INT311128 Positive_regulation of Regulation of Apoe 1 0.30 0.3 0.3
107 INT71036 Negative_regulation of TRERF1 1 0.00 0.47 0.3
108 INT175687 Transcription of Apoe 4 0.72 2.12 0.29
109 INT96815 Regulation of Gene_expression of APOE 2 0.62 1.1 0.29
110 INT53814 Regulation of Positive_regulation of Cel 2 0.23 0.45 0.29
111 INT281746 Negative_regulation of Localization of CEL 1 0.03 0.6 0.29
112 INT244618 Regulation of TRERF1 2 0.07 1.43 0.28
113 INT344673 Positive_regulation of Binding of Scarb1 1 0.16 0.82 0.28
114 INT51857 Positive_regulation of Phosphorylation of Akr1d1 1 0.01 0 0.27
115 INT51854 Phosphorylation of Akr1d1 1 0.02 0 0.27
116 INT97711 Positive_regulation of Transcription of Apoe 1 0.46 1.06 0.27
117 INT254756 Regulation of Positive_regulation of Apoe 1 0.20 0.22 0.26
118 INT175459 Binding of Cel 2 0.11 6.62 0.24
119 INT16158 Protein_catabolism of CEL 1 0.64 0 0.24
120 INT329886 Transcription of CYP7A1 1 0.28 0.45 0.23
121 INT307183 Positive_regulation of Gene_expression of Scarb1 1 0.07 0.93 0.22
122 INT323964 Negative_regulation of Binding of Apoe 1 0.39 0.35 0.22
123 INT198892 Regulation of Binding of Apoe 6 0.45 2.94 0.21
124 INT186199 Binding of SCARB1 3 0.37 5.25 0.21
125 INT202425 Negative_regulation of Transcription of CEL 1 0.03 0.49 0.21
126 INT193810 Phosphorylation of APOE 2 0.27 1.13 0.2
127 INT290336 Negative_regulation of Scarb1 4 0.31 1.77 0.17
128 INT211552 Localization of Scarb1 3 0.60 1.27 0.17
129 INT254754 Regulation of Localization of Apoe 1 0.20 0.39 0.17
130 INT254755 Positive_regulation of Transcription of Apoe 1 0.16 0.41 0.16
131 INT96772 Positive_regulation of Gene_expression of APOE 5 0.66 5.44 0.14
132 INT198894 Regulation of Gene_expression of Apoe 2 0.44 0.56 0.14
133 INT173171 Gene_expression of CYP7A1 2 0.45 1.02 0.14
134 INT175454 Positive_regulation of Binding of Cel 1 0.15 0.92 0.14
135 INT59956 Positive_regulation of SCARB1 3 0.49 0.99 0.12
136 INT104623 Regulation of Negative_regulation of Apoe 2 0.45 0.73 0.12
137 INT173188 Regulation of Gene_expression of CYP7A1 1 0.22 0.48 0.12
138 INT326081 Negative_regulation of Localization of APOE 1 0.56 2.23 0.11
139 INT300643 Positive_regulation of Binding of APOE 1 0.44 0.8 0.09
140 INT44609 Negative_regulation of Positive_regulation of APOE 1 0.16 0.9 0.09
141 INT225029 Gene_expression of TRERF1 3 0.53 1.62 0.08
142 INT229319 Regulation of Positive_regulation of CYP7A1 1 0.30 0.42 0.08
143 INT205147 Regulation of Phosphorylation of APOE 1 0.06 0.34 0.07
144 INT97709 Positive_regulation of Localization of Apoe 1 0.68 1.02 0.07
145 INT229325 Positive_regulation of Gene_expression of CYP7A1 1 0.34 0.6 0.05
146 INT208336 Positive_regulation of Binding of Apoe 1 0.48 0.7 0.05
147 INT208333 Positive_regulation of Positive_regulation of Apoe 1 0.48 0.65 0.05
148 INT290345 Negative_regulation of Gene_expression of Scarb1 1 0.42 0.5 0.04
149 INT290334 Negative_regulation of Binding of Scarb1 1 0.31 0.12 0.03
150 INT345480 Binding of CYP7A1 1 0.29 0 0.03
151 INT326070 Regulation of Localization of APOE 1 0.58 1.21 0.03
152 INT191285 Positive_regulation of Localization of APOE 3 0.66 3.06 0
153 INT326073 Transcription of APOE 2 0.51 1.94 0
154 INT50081 Positive_regulation of Positive_regulation of APOE 2 0.49 0.18 0
155 INT176172 Transcription of Cyp7a1 1 0.57 1.04 0
156 INT176179 Negative_regulation of Positive_regulation of Cyp7a1 1 0.34 0.4 0
157 INT238790 Regulation of Gene_expression of Cel 1 0.07 1.27 0
158 INT187419 Regulation of CYP7A1 1 0.05 0.23 0
159 INT176215 Regulation of Transcription of Cyp7a1 1 0.49 0.79 0
160 INT186198 Positive_regulation of Transcription of SCARB1 1 0.49 0.67 0
161 INT352610 Regulation of Regulation of CEL 1 0.00 0.55 0
162 INT290350 Transcription of Scarb1 1 0.50 0.24 0
163 INT97442 Positive_regulation of Binding of CEL 1 0.67 0 0
164 INT225028 Binding of TRERF1 1 0.29 0 0
165 INT290341 Positive_regulation of Negative_regulation of Scarb1 1 0.32 0.69 0
166 INT326524 Negative_regulation of Transcription of APOE 1 0.30 1.71 0
167 INT212958 Positive_regulation of Scarb1 1 0.20 1.29 0
168 INT213135 Negative_regulation of Scarb1 1 0.02 2.06 0
169 INT186195 Transcription of SCARB1 1 0.70 1.42 0
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