GO:0006809

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Name nitric oxide biosynthetic process
Categary Process
Go Slim No
Go Link GO:0006809
Unique Molecular Interactions 941
Total Molecular Interactions 1245
Total Single Events 18484
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nitric oxide biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for nitric oxide biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6
2 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
3 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
4 INT108472 Binding of NOS1 and PNOC 1 0.32 0.64 3.27
5 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
6 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
7 INT251150 Binding of Nos1 and Dlg2 1 0.30 1.98 2.62
8 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
9 INT169346 Nxn Negative_regulation of Dynll1 1 0.06 1.22 1.87
10 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84
11 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75
12 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73
13 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 0.01 0.95 1.67
14 INT236491 GCH1 Regulation of Pain1 1 0.01 0.89 1.65
15 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
16 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
17 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
18 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
19 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
20 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
21 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25
22 INT132465 Ltf Positive_regulation of Nos1 1 0.35 0.05 1.24
23 INT261410 Slc7a2 Positive_regulation of Ltp 1 0.06 0.08 1.21
24 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
25 INT142572 D5Pas1 Negative_regulation of Nos1 2 0.02 0.14 1.11
26 INT317527 Binding of Hint1 and Nos1 1 0.27 0.1 1.11
27 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08
28 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
29 INT132464 Ltf Negative_regulation of Positive_regulation of Nos1 1 0.33 0 1.03
30 INT88887 IRF6 Positive_regulation of Transcription of Nos2 1 0.21 0.27 1.02
31 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
32 INT119914 Olr1714 Negative_regulation of Nos1 1 0.02 0.47 1.01
33 INT88884 IRF6 Regulation of Nos2 1 0.12 0.26 1
34 INT317555 Nos1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
35 INT88886 IRF6 Positive_regulation of Nos2 1 0.22 0.26 1
36 INT88888 Regulation of IRF6 Positive_regulation of Nos2 1 0.20 0.26 1
37 INT170449 Pax3 Positive_regulation of Spr 1 0.01 0.26 0.99
38 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96
39 INT274899 Positive_regulation of P2rx4 Positive_regulation of Localization of Gtf3a 1 0.02 1.67 0.95
40 INT146579 Hba Negative_regulation of Gene_expression of Nos2 1 0.44 1.01 0.95
41 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
42 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
43 INT317530 Negative_regulation of Binding of Nos1 and Oprm1 1 0.21 0.06 0.9
44 INT108687 Nfkb1 Regulation of Positive_regulation of Nos2 1 0.50 1.28 0.88
45 INT108686 Nfkb1 Regulation of Nos2 1 0.69 1.27 0.88
46 INT160412 Tat Positive_regulation of Transcription of Nos2 1 0.37 0.98 0.86
47 INT120825 Adcyap1 Positive_regulation of Localization of Nos1 1 0.26 0.62 0.85
48 INT102931 Nos3 Positive_regulation of Nos2 1 0.43 1.63 0.83
49 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
50 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
51 INT155761 Binding of Nos1 and Tjp1 1 0.13 1.01 0.82
52 INT185937 NOS2 Regulation of Prkaca 1 0.03 1.08 0.82
53 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
54 INT102932 Nos3 Positive_regulation of NOS1 1 0.03 1.63 0.82
55 INT155760 Binding of Nos1 and Dlg4 1 0.13 1.01 0.82
56 INT235087 NOS1 Positive_regulation of Localization of ABAT 1 0.02 0.61 0.81
57 INT88885 IRF6 Positive_regulation of Gene_expression of Nos2 1 0.21 0.1 0.81
58 INT88878 Negative_regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.06 0.1 0.81
59 INT349657 Nos2 Regulation of Regulation of Nos1 1 0.24 0.9 0.8
60 INT96501 Il11 Regulation of Gene_expression of NOS2 1 0.00 1.04 0.8
61 INT168455 Sult1a1 Negative_regulation of Nos2 1 0.08 1.99 0.79
62 INT168456 Arr3 Positive_regulation of Nos2 1 0.21 1.98 0.79
63 INT132889 Nfkb1 Regulation of Gene_expression of Nos2 1 0.16 0.21 0.79
64 INT132894 CHUK Regulation of Gene_expression of Nos2 1 0.00 0.21 0.79
65 INT97863 Binding of NOS1 and GRHPR 1 0.05 0.23 0.77
66 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
67 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
68 INT90125 Nfkb1 Regulation of Gene_expression of Nos1 1 0.17 0.39 0.76
69 INT90116 Nfkb1 Positive_regulation of Gene_expression of Nos1 1 0.32 0.39 0.76
70 INT108611 Adra2a Regulation of Gene_expression of Nos1 1 0.10 0 0.75
71 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74
72 INT159593 Regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.38 0.46 0.74
73 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74
74 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73
75 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
76 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
77 INT187522 ATIC Negative_regulation of Gene_expression of Nos2 1 0.02 1.46 0.7
78 INT149983 Binding of Cpox and Nos2 1 0.30 0.54 0.69
79 INT106154 Calca Positive_regulation of Nos1 1 0.29 0.2 0.68
80 INT197233 Positive_regulation of Rora Positive_regulation of Localization of Helt 1 0.00 0 0.68
81 INT347962 Cpox Negative_regulation of Positive_regulation of Nos1 1 0.02 0.59 0.67
82 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
83 INT220032 Nos1 Positive_regulation of Nos3 1 0.32 0.45 0.66
84 INT220035 Nos1 Positive_regulation of Nos2 1 0.29 0.45 0.66
85 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
86 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 2 0.03 0.24 0.65
87 INT78663 Dlst Regulation of Nos1 1 0.19 0.91 0.65
88 INT135829 Cat2 Regulation of Nos2 1 0.47 0 0.65
89 INT169293 PTPLA Positive_regulation of AKT1 1 0.10 0.15 0.64
90 INT235082 CA2 Positive_regulation of NOS1 2 0.11 0.62 0.63
91 INT266489 Dcps Positive_regulation of Gene_expression of Nos2 1 0.06 3.43 0.63
92 INT278695 MTX1 Negative_regulation of Phosphorylation of AKT1 1 0.04 0.81 0.62
93 INT128812 Mapk8 Negative_regulation of Gene_expression of Nos2 1 0.19 0.37 0.61
94 INT128817 Ephb1 Negative_regulation of Gene_expression of Nos2 1 0.16 0.37 0.61
95 INT124831 Fbp1 Positive_regulation of Nos2 1 0.36 0.64 0.61
96 INT339072 Eae1 Positive_regulation of Gene_expression of Nos2 1 0.02 3.76 0.59
97 INT175700 Nos3 Negative_regulation of smc 1 0.01 1.05 0.59
98 INT128810 Il1b Positive_regulation of Gene_expression of Nos2 1 0.04 0.31 0.59
99 INT170446 Pax3 Positive_regulation of Gene_expression of Spr 1 0.01 0 0.58
100 INT143426 Positive_regulation of B4GALNT1 Negative_regulation of Gene_expression of Nos2 1 0.00 0.83 0.58
101 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57
102 INT151459 Olr1745 Negative_regulation of Gene_expression of Nos2 1 0.04 0.82 0.57
103 INT142571 Pnoc Positive_regulation of Nos1 1 0.52 0.06 0.57
104 INT78588 Positive_regulation of Binding of Nfkb1 and Nos2 1 0.01 0.33 0.56
105 INT81546 TNF Positive_regulation of Gene_expression of Nos2 1 0.04 0.54 0.56
106 INT201944 CXCL10 Positive_regulation of Phosphorylation of AKT1 1 0.09 0.79 0.55
107 INT78587 Binding of Nfkb1 and Nos2 1 0.01 0.33 0.55
108 INT278228 Binding of MBNL1 and NOS3 1 0.05 2.06 0.54
109 INT97425 Prkcg Regulation of Regulation of Nos1 1 0.06 0 0.53
110 INT121081 Negative_regulation of NOS1 Negative_regulation of Slep1 1 0.00 0 0.52
111 INT191947 NFKB2 Positive_regulation of Gene_expression of NOS2 1 0.08 1.51 0.52
112 INT97952 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of AKT1 1 0.03 0.72 0.51
113 INT78590 Nos2 Positive_regulation of PTGS1 2 0.00 0.85 0.5
114 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5
115 INT97951 ST3GAL3 Positive_regulation of AKT1 1 0.04 0.7 0.5
116 INT317537 Oprm1 Positive_regulation of Phosphorylation of Nos1 1 0.16 0 0.5
117 INT90131 NOS1 Regulation of Fos 1 0.00 0.25 0.49
118 INT235090 Positive_regulation of GRIN1 Positive_regulation of NOS1 1 0.42 0.81 0.49
119 INT132060 NBN Positive_regulation of Nos2 1 0.01 0.21 0.49
120 INT212806 Rngtt Negative_regulation of Gene_expression of Nos2 1 0.03 0.9 0.49
121 INT186713 IK Positive_regulation of Gene_expression of NOS1 1 0.00 0.55 0.49
122 INT90121 Nos1 Regulation of Fos 1 0.27 0.25 0.49
123 INT191948 NFKB1 Regulation of Gene_expression of NOS2 1 0.38 1 0.47
124 INT191950 NFKB2 Regulation of Gene_expression of NOS2 1 0.08 1 0.47
125 INT72928 Magel2 Negative_regulation of Positive_regulation of NOS1 1 0.01 0 0.47
126 INT257220 Binding of Nos1 and Flvcr2 1 0.00 0.17 0.47
127 INT162932 TXNRD1 Negative_regulation of Phosphorylation of AKT1 1 0.14 1.01 0.47
128 INT149652 Zfp36 Regulation of Nos2 1 0.09 0.42 0.47
129 INT314200 Positive_regulation of Binding of Nos2 and Tnf 1 0.42 0.34 0.46
130 INT103025 Calca Positive_regulation of Nos3 1 0.25 0.41 0.46
131 INT314201 Binding of Nos2 and Tnf 1 0.31 0.33 0.46
132 INT103027 Ptgis Positive_regulation of Nos3 1 0.06 0.42 0.46
133 INT95276 Obfc2a Negative_regulation of Nos3 1 0.02 1.02 0.46
134 INT162929 NQO1 Negative_regulation of Phosphorylation of AKT1 1 0.41 1 0.46
135 INT103030 Calca Positive_regulation of Positive_regulation of Nos3 1 0.26 0.41 0.46
136 INT354981 Cacna1a Negative_regulation of Gene_expression of Nos2 1 0.01 0.99 0.45
137 INT116610 Positive_regulation of Lnpep Regulation of Nos2 1 0.16 0.62 0.44
138 INT116608 Lnpep Regulation of Nos2 1 0.14 0.62 0.44
139 INT148634 Abat Negative_regulation of Transcription of Nos2 1 0.19 0.52 0.44
140 INT212809 Il6 Positive_regulation of Gene_expression of Nos2 1 0.08 0.75 0.43
141 INT212810 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.03 0.74 0.43
142 INT159349 Zfp956 Negative_regulation of Nos1 1 0.03 0.61 0.43
143 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
144 INT116611 Lnpep Positive_regulation of Binding of Nos2 1 0.16 0.62 0.42
145 INT160048 INPPL1 Regulation of Gene_expression of AKT1 1 0.28 0.6 0.42
146 INT121851 AKT1 Regulation of ROS1 1 0.16 0.52 0.41
147 INT121848 AKT1 Regulation of CASP8 1 0.18 0.52 0.41
148 INT111410 Nos1 Regulation of Vip 1 0.00 0 0.41
149 INT135972 Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.04 0.54 0.41
150 INT146273 Binding of Nos1 and Rasd1 1 0.34 0.18 0.41
151 INT111409 Nos1 Regulation of Gene_expression of Vip 1 0.01 0 0.41
152 INT121854 AKT1 Regulation of BID 1 0.17 0.52 0.41
153 INT156438 Cpox Positive_regulation of Nos2 3 0.14 1.24 0.4
154 INT97789 Positive_regulation of Cnr1 Negative_regulation of Gene_expression of Nos2 1 0.12 0.23 0.4
155 INT187487 Cebpg Positive_regulation of Gene_expression of Nos2 1 0.03 0.38 0.4
156 INT108197 AKT1 Regulation of JUN 1 0.29 0.25 0.4
157 INT121853 Gene_expression of ROS1 Negative_regulation of AKT1 1 0.25 0.49 0.4
158 INT81300 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.02 0.38 0.39
159 INT146272 Binding of Nos1 and Nos1ap 1 0.28 0.2 0.39
160 INT201274 Car2 Regulation of Gene_expression of Nos1 1 0.05 1.15 0.38
161 INT61954 IFNA1 Positive_regulation of Nos2 1 0.05 0.46 0.38
162 INT109683 NOS1 Positive_regulation of Positive_regulation of ISYNA1 1 0.01 0.11 0.38
163 INT235091 CALM1 Positive_regulation of NOS1 1 0.02 0.63 0.37
164 INT320591 Ca2 Positive_regulation of Nos1 1 0.07 0.09 0.37
165 INT89386 INS Positive_regulation of Phosphorylation of AKT1 3 0.43 1.48 0.36
166 INT299288 AKT1 Positive_regulation of RPTOR 1 0.34 0.05 0.36
167 INT168426 RYBP Regulation of Nos2 1 0.01 0.4 0.36
168 INT80444 Binding of EDNRA and SPR 1 0.05 0.1 0.36
169 INT168424 Ptger2 Regulation of Binding of Nos2 1 0.22 0.52 0.36
170 INT97790 Foxm1 Negative_regulation of Gene_expression of Nos2 1 0.03 0.16 0.36
171 INT152240 Nfasc Regulation of Gene_expression of Nos2 1 0.06 0.19 0.36
172 INT168423 Ptger2 Regulation of Nos2 1 0.13 0.52 0.36
173 INT278226 Binding of FOSB and NOS3 1 0.03 1.22 0.36
174 INT89500 Nos2 Positive_regulation of Il6 1 0.04 1.07 0.35
175 INT323885 LEP Regulation of Gene_expression of NOS2 1 0.26 1.07 0.35
176 INT176135 AKT1 Regulation of Localization of CYCS 1 0.43 2.16 0.35
177 INT187488 Positive_regulation of Ros1 Positive_regulation of Gene_expression of Nos2 1 0.01 0.88 0.35
178 INT175319 Negative_regulation of Nos2 Negative_regulation of Positive_regulation of Pnlip 1 0.01 0.83 0.34
179 INT276214 Binding of Nos2 and Nfkb1 1 0.12 0.31 0.34
180 INT89505 Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
181 INT105768 Binding of Nos1 and Nqo1 1 0.00 0.26 0.34
182 INT354985 Cacna1a Regulation of Nos2 1 0.01 0.73 0.34
183 INT110758 Tnfaip8 Positive_regulation of Positive_regulation of Nos2 1 0.14 0.88 0.34
184 INT276209 Negative_regulation of Binding of Nos2 and Nfkb1 1 0.14 0.31 0.34
185 INT144448 Nqo1 Regulation of Nos1 1 0.11 0.09 0.34
186 INT303126 Nos2 Positive_regulation of Gene_expression of Il6 1 0.13 4.38 0.34
187 INT144450 Regulation of Nqo1 Regulation of Nos1 1 0.11 0.1 0.34
188 INT89502 Positive_regulation of Nos2 Positive_regulation of Ptgs2 1 0.05 1.07 0.34
189 INT110761 Tnfaip8 Positive_regulation of Nos2 1 0.13 0.88 0.34
190 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33
191 INT230855 KNG1 Regulation of NOS1 2 0.03 0.94 0.33
192 INT333158 asa Positive_regulation of Nos3 1 0.11 0.18 0.32
193 INT333166 Tlx2 Positive_regulation of Gene_expression of Nos3 1 0.08 0.18 0.32
194 INT344036 Binding of NOS1 and SPTB 1 0.01 0.31 0.32
195 INT333155 Tlx2 Regulation of Gene_expression of Nos3 1 0.08 0.18 0.32
196 INT333152 Tlx2 Positive_regulation of Nos3 1 0.08 0.18 0.32
197 INT333169 asa Positive_regulation of Gene_expression of Nos3 1 0.11 0.18 0.32
198 INT78664 Negative_regulation of Nos1 Negative_regulation of Cebpz 1 0.30 0.43 0.32
199 INT337410 AKT3 Negative_regulation of AKT1 1 0.09 0.49 0.32
200 INT333164 asa Regulation of Nos3 1 0.11 0.18 0.32

Single Events

The table below shows the top 100 pain related interactions that have been reported for nitric oxide biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in nitric oxide biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
2 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07
3 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
4 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85
5 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71
6 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76
7 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
8 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43
9 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32
10 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
11 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61
12 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87
13 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
14 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
15 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64
16 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
17 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
18 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65
19 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56
20 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94
21 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
22 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84
23 INT92837 Negative_regulation of Gene_expression of Nos2 116 0.59 59.67 31.82
24 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72
25 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68
26 INT61953 Transcription of Nos2 101 0.72 46.64 25.49
27 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
28 INT48766 Regulation of NOS1 73 0.61 37.01 24.59
29 INT89854 Regulation of Nos2 49 0.61 42.58 24.1
30 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01
31 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96
32 INT49172 Regulation of Nos1 43 0.52 27.53 23.66
33 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72
34 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
35 INT112427 Positive_regulation of P2rx4 27 0.68 26.29 21.31
36 INT66281 Transcription of Nos2 81 0.71 39.49 20.37
37 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
38 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
39 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71
40 INT150934 Gene_expression of GCH1 17 0.78 14.54 17.53
41 INT61949 Regulation of Nos2 74 0.58 34.08 16.7
42 INT77433 Regulation of Gene_expression of Nos2 49 0.62 35.07 16.33
43 INT114025 Transcription of Nos1 20 0.70 16.48 15.63
44 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
45 INT74098 Negative_regulation of Gene_expression of Nos1 36 0.59 16.25 14.82
46 INT64112 Regulation of Gene_expression of Nos1 22 0.62 21.45 14.76
47 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99
48 INT121242 Positive_regulation of Gene_expression of Nos3 37 0.69 31.96 12.71
49 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
50 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
51 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47
52 INT122053 Positive_regulation of P2rx4 16 0.69 13.02 11.98
53 INT73431 Positive_regulation of Nos3 82 0.65 53.22 11.61
54 INT97381 Negative_regulation of Positive_regulation of Nos2 34 0.59 16.66 11.6
55 INT95369 Positive_regulation of Gene_expression of NOS2 36 0.55 25.09 11.37
56 INT80251 Binding of Nos1 21 0.30 8.24 11.31
57 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15
58 INT48912 Localization of NOS1 52 0.77 24.14 10.92
59 INT90114 Regulation of Gene_expression of Nos1 18 0.62 6.38 10.52
60 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42
61 INT110017 Phosphorylation of Nos1 12 0.60 1.64 10.3
62 INT139443 Positive_regulation of GCH1 9 0.69 8.2 10.14
63 INT95271 Negative_regulation of Nos3 46 0.53 24.1 9.71
64 INT70850 Positive_regulation of Transcription of Nos2 30 0.70 18.95 9.68
65 INT112428 Positive_regulation of Gene_expression of P2rx4 12 0.68 12.67 9.57
66 INT168991 Negative_regulation of P2rx4 9 0.43 12.77 9.39
67 INT125444 Gene_expression of Rora 5 0.75 3.05 8.97
68 INT48908 Transcription of NOS1 27 0.55 13.46 8.39
69 INT84672 Negative_regulation of Positive_regulation of Nos1 12 0.48 3.76 8.27
70 INT116605 Binding of Nos2 28 0.37 16.88 8.18
71 INT72337 Positive_regulation of Positive_regulation of Nos2 37 0.65 17.02 8.11
72 INT114023 Positive_regulation of Transcription of Nos1 7 0.60 5.35 8.06
73 INT71381 Localization of Nos1 33 0.79 11.46 8.05
74 INT136177 Gene_expression of P2rx4 8 0.75 6.74 8.05
75 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92
76 INT172789 Regulation of Gene_expression of Nos3 15 0.53 16.23 7.86
77 INT112191 Positive_regulation of Transcription of Nos2 22 0.66 12.4 7.74
78 INT85751 Positive_regulation of Positive_regulation of Nos2 40 0.60 23.53 7.72
79 INT57176 Positive_regulation of Dynll1 9 0.49 4.76 7.71
80 INT65246 Negative_regulation of Nos3 36 0.50 25.65 7.62
81 INT152347 Binding of GCH1 8 0.37 6.13 7.36
82 INT74099 Negative_regulation of Dynll1 8 0.56 3.43 7.25
83 INT112430 Negative_regulation of P2rx4 9 0.57 8.4 6.63
84 INT92741 Positive_regulation of Positive_regulation of Nos1 8 0.47 1.44 6.58
85 INT89131 Negative_regulation of NOS2 20 0.58 9.68 6.56
86 INT83712 Transcription of Nos3 19 0.69 13.09 6.31
87 INT69499 Binding of Nos1 15 0.36 2.56 6.23
88 INT93658 Transcription of Nos1 16 0.72 6.85 6.16
89 INT163776 Regulation of GCH1 7 0.27 4.58 6.16
90 INT64111 Negative_regulation of Gene_expression of Nos1 22 0.57 8.96 6.02
91 INT48911 Binding of NOS1 24 0.40 11.21 5.89
92 INT170443 Gene_expression of Spr 1 0.12 0.07 5.88
93 INT257199 Positive_regulation of Phosphorylation of Nos1 2 0.45 0.68 5.78
94 INT94428 Negative_regulation of Gene_expression of NOS2 20 0.47 11.61 5.62
95 INT84673 Localization of Nos1 19 0.80 5.01 5.62
96 INT215594 Negative_regulation of Gene_expression of P2rx4 7 0.48 6.46 5.22
97 INT86717 Negative_regulation of Positive_regulation of NOS1 18 0.30 8.88 5.2
98 INT112190 Regulation of Negative_regulation of Nos2 8 0.62 5.83 5.09
99 INT145681 Regulation of P2rx4 4 0.61 3.41 5.09
100 INT73608 Localization of Nos2 21 0.75 9.58 5.05
101 INT40782 Gene_expression of Slc7a2 10 0.57 4.59 5
102 INT89132 Regulation of NOS2 9 0.61 7.34 4.95
103 INT105336 Regulation of AKT1 52 0.56 32.53 4.89
104 INT61950 Regulation of Positive_regulation of Nos2 17 0.43 9.01 4.87
105 INT76581 Regulation of Negative_regulation of NOS1 14 0.45 7.49 4.4
106 INT74393 Gene_expression of Dynll1 8 0.65 2.64 4.39
107 INT94427 Positive_regulation of Positive_regulation of NOS2 14 0.47 11.15 4.3
108 INT89784 Regulation of Transcription of Nos2 14 0.42 8.39 4.24
109 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21
110 INT83991 Regulation of Nos3 25 0.44 9.89 4.06
111 INT102515 Binding of Nos3 19 0.45 9.41 4.01
112 INT80473 Gene_expression of Spr 5 0.46 2.76 3.86
113 INT169344 Positive_regulation of Gene_expression of Dynll1 3 0.49 2.34 3.48
114 INT134875 Phosphorylation of Nos1 5 0.70 1.21 3.44
115 INT61952 Negative_regulation of Transcription of Nos2 17 0.54 5.1 3.34
116 INT142568 Negative_regulation of Positive_regulation of Nos1 2 0.37 0.25 3.3
117 INT70958 Binding of NOS3 19 0.37 11.84 3.29
118 INT126223 Binding of Nos2 17 0.37 6 3.22
119 INT108203 Negative_regulation of Gene_expression of AKT1 28 0.54 16.38 3.19
120 INT116235 Negative_regulation of Transcription of Nos2 23 0.58 7.91 3.14
121 INT92814 Negative_regulation of NOS3 25 0.51 20.67 3.07
122 INT89392 Negative_regulation of Positive_regulation of AKT1 23 0.50 15.69 3.02
123 INT101406 Regulation of Spr 3 0.25 1.32 2.95
124 INT112429 Negative_regulation of Positive_regulation of P2rx4 4 0.57 4.03 2.94
125 INT89133 Transcription of NOS2 13 0.71 6.84 2.93
126 INT91869 Transcription of NOS3 13 0.67 6.81 2.86
127 INT85750 Regulation of Positive_regulation of Nos2 10 0.54 7.78 2.83
128 INT112431 Positive_regulation of Positive_regulation of P2rx4 2 0.49 3.52 2.81
129 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8
130 INT150933 Negative_regulation of Positive_regulation of GCH1 3 0.58 1.8 2.77
131 INT101883 Regulation of Gene_expression of Nos3 11 0.52 6.71 2.73
132 INT190881 Positive_regulation of Rora 2 0.43 1.76 2.71
133 INT90675 Negative_regulation of Gene_expression of Nos3 15 0.46 11.11 2.7
134 INT49169 Regulation of Negative_regulation of Nos1 3 0.45 4.67 2.7
135 INT72757 Negative_regulation of Negative_regulation of Nos2 8 0.42 4.23 2.68
136 INT170439 Positive_regulation of Spr 1 0.10 0.3 2.67
137 INT122054 Positive_regulation of Positive_regulation of P2rx4 3 0.49 2.85 2.65
138 INT136176 Positive_regulation of Gene_expression of P2rx4 5 0.60 3.18 2.64
139 INT108608 Positive_regulation of Positive_regulation of Nos1 8 0.49 1.66 2.58
140 INT97523 Phosphorylation of NOS1 3 0.46 0.59 2.58
141 INT150932 Positive_regulation of Gene_expression of GCH1 3 0.70 2.07 2.57
142 INT89852 Localization of Nos2 22 0.78 14.89 2.56
143 INT125442 Negative_regulation of Gene_expression of Rora 5 0.57 2.92 2.54
144 INT145101 Transcription of Nos3 8 0.70 6.04 2.47
145 INT79609 Positive_regulation of Negative_regulation of Nos2 5 0.49 3.6 2.43
146 INT197228 Positive_regulation of Gene_expression of Rora 1 0.05 0 2.43
147 INT76094 Localization of NOS2 8 0.72 2.76 2.34
148 INT165434 Regulation of SPR 4 0.24 2.14 2.33
149 INT283973 Transcription of GCH1 1 0.61 1.99 2.33
150 INT73809 Regulation of Nos3 18 0.45 10.05 2.27
151 INT144792 Negative_regulation of Transcription of Nos1 2 0.43 1.74 2.27
152 INT283975 Negative_regulation of Localization of GCH1 1 0.38 1.99 2.27
153 INT118791 Binding of AKT1 32 0.48 15.51 2.25
154 INT132669 Positive_regulation of Transcription of NOS1 7 0.44 4.43 2.19
155 INT141299 Negative_regulation of Gene_expression of Nos3 9 0.55 5.38 2.17
156 INT110016 Negative_regulation of Phosphorylation of Nos1 3 0.28 0.47 2.16
157 INT104263 Regulation of Positive_regulation of NOS1 5 0.28 3.15 2.15
158 INT121884 Regulation of Binding of Nos1 2 0.33 1.63 2.15
159 INT101866 Positive_regulation of Gene_expression of AKT1 49 0.52 17.47 2.14
160 INT89130 Positive_regulation of Transcription of NOS2 7 0.50 3.32 2.14
161 INT281928 Gene_expression of ARG2 3 0.77 63.17 2.14
162 INT82166 Regulation of NOS3 14 0.54 7.57 2.08
163 INT52865 Positive_regulation of Spr 2 0.49 0.56 2.06
164 INT91594 Localization of NOS3 12 0.78 5.39 2.02
165 INT258637 Regulation of Gene_expression of GCH1 1 0.62 1.77 2.02
166 INT79198 Positive_regulation of Positive_regulation of Dynll1 2 0.42 0.99 1.99
167 INT76532 Binding of Nos3 13 0.37 9.32 1.87
168 INT123130 Positive_regulation of Positive_regulation of AKT1 22 0.49 11.77 1.83
169 INT8556 Positive_regulation of NQO1 12 0.70 5.11 1.78
170 INT60999 Localization of Nos3 12 0.74 5.28 1.75
171 INT107923 Regulation of Gene_expression of NOS3 11 0.61 2.73 1.73
172 INT79063 Regulation of Gene_expression of NOS2 6 0.43 3.68 1.7
173 INT64559 Positive_regulation of Negative_regulation of Nos1 2 0.41 1.58 1.68
174 INT97418 Regulation of Regulation of Nos1 2 0.41 0.94 1.68
175 INT80469 Negative_regulation of Spr 2 0.30 1.62 1.61
176 INT167288 Regulation of Dynll1 3 0.45 1.22 1.56
177 INT181574 Phosphorylation of Nos2 9 0.70 2.92 1.55
178 INT101405 Binding of Spr 1 0.20 0.43 1.55
179 INT96047 Positive_regulation of Localization of NOS1 6 0.38 4.24 1.47
180 INT146941 Negative_regulation of Positive_regulation of P2rx4 2 0.37 1.36 1.47
181 INT304433 Localization of P2rx4 1 0.69 0 1.44
182 INT304444 Negative_regulation of Gene_expression of P2rx4 1 0.51 0.75 1.43
183 INT181639 Positive_regulation of Positive_regulation of NOS3 8 0.41 3.72 1.41
184 INT61951 Regulation of Negative_regulation of Nos2 5 0.58 3.08 1.39
185 INT83713 Positive_regulation of Transcription of Nos3 3 0.67 2.92 1.38
186 INT89785 Regulation of Transcription of Nos3 1 0.32 0.85 1.36
187 INT91863 Negative_regulation of Gene_expression of NOS3 13 0.51 9.43 1.34
188 INT115938 Negative_regulation of Negative_regulation of Nos1 2 0.36 0.27 1.31
189 INT136612 Positive_regulation of Positive_regulation of Nos3 5 0.43 4.22 1.26
190 INT61395 Negative_regulation of Negative_regulation of NOS1 5 0.30 1.83 1.25
191 INT40783 Localization of Slc7a2 1 0.62 0 1.25
192 INT144392 Negative_regulation of Negative_regulation of Nos2 2 0.42 1.83 1.24
193 INT212983 Positive_regulation of Positive_regulation of Nos3 9 0.51 7.08 1.23
194 INT167409 Regulation of Gene_expression of AKT1 8 0.56 4.86 1.23
195 INT170440 Positive_regulation of Gene_expression of Spr 1 0.10 0 1.21
196 INT135556 Localization of AKT1 38 0.69 12.78 1.17
197 INT80471 Negative_regulation of Gene_expression of Spr 1 0.22 1.19 1.16
198 INT118792 Regulation of Positive_regulation of AKT1 8 0.61 3.73 1.15
199 INT144393 Negative_regulation of Negative_regulation of Nos1 2 0.32 0.96 1.15
200 INT176147 Regulation of Phosphorylation of AKT1 14 0.41 6.41 1.13
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