GO:0006826

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Name iron ion transport
Categary Process
Go Slim No
Go Link GO:0006826
Unique Molecular Interactions 144
Total Molecular Interactions 175
Total Single Events 1269
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for iron ion transport. They are ordered first by their pain relevance and then by number of times they were reported for iron ion transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
2 INT132465 Ltf Positive_regulation of Nos1 1 0.35 0.05 1.24
3 INT132464 Ltf Negative_regulation of Positive_regulation of Nos1 1 0.33 0 1.03
4 INT152490 Slc40a1 Negative_regulation of Faah 1 0.01 0.73 0.98
5 INT193279 Phax Regulation of Fth1 1 0.01 0.16 0.81
6 INT110726 Binding of ALB and LTF 1 0.01 0 0.81
7 INT209043 Binding of Fn1 and Slc11a1 3 0.03 1.91 0.78
8 INT772 Tf Positive_regulation of Positive_regulation of Oprl1 1 0.11 0 0.7
9 INT778 Tf Positive_regulation of Gh1 1 0.14 0 0.7
10 INT782 Tf Positive_regulation of Prl 1 0.43 0 0.7
11 INT293010 ELANE Regulation of Localization of LTF 1 0.00 0.54 0.67
12 INT209063 Slc11a1 Positive_regulation of Il17a 1 0.11 0.4 0.65
13 INT193290 CAP1 Regulation of Fth1 1 0.02 0 0.6
14 INT40901 Trf Regulation of Localization of POMC 1 0.07 0.56 0.6
15 INT39210 TF Positive_regulation of Gene_expression of IL2 1 0.17 0.07 0.57
16 INT197380 Tbs1 Positive_regulation of Sfxn1 1 0.00 0 0.5
17 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48
18 INT132445 TF Positive_regulation of IL8 1 0.11 2.23 0.46
19 INT69638 Binding of TF and Zfp354a 1 0.00 0 0.46
20 INT84517 IRF6 Positive_regulation of TF 1 0.14 0.19 0.44
21 INT209049 Slc11a1 Positive_regulation of Localization of Il12a 1 0.04 0.09 0.44
22 INT110727 Binding of HBM and LTF 1 0.00 0 0.41
23 INT84516 NFKB1 Positive_regulation of Gene_expression of TF 1 0.10 0.09 0.41
24 INT84518 IRF6 Positive_regulation of Gene_expression of TF 1 0.14 0.09 0.41
25 INT58480 Agpat1 Regulation of TF 1 0.00 0.46 0.4
26 INT58481 Crp Regulation of TF 1 0.01 0.46 0.4
27 INT84521 Binding of F7 and TF 1 0.06 0.09 0.37
28 INT209047 Slc11a1 Positive_regulation of Localization of Il10 1 0.10 0.52 0.36
29 INT204943 Il6 Regulation of Slc39a14 1 0.00 0.54 0.36
30 INT272412 VSX1 Positive_regulation of Gene_expression of Slc11a1 1 0.00 0.57 0.35
31 INT326438 Binding of HFE and TAPVR1 1 0.01 0.48 0.29
32 INT84523 TRAF3IP2 Regulation of Gene_expression of TF 1 0.05 0.1 0.27
33 INT262809 Il10 Positive_regulation of Regulation of Slc11a1 1 0.17 1.12 0.27
34 INT84519 TRAF3IP2 Positive_regulation of Gene_expression of TF 1 0.05 0.1 0.27
35 INT3577 Tf Negative_regulation of Positive_regulation of Gh1 1 0.49 0 0.27
36 INT262810 Slc11a1 Positive_regulation of Gene_expression of Il10 1 0.20 0.97 0.27
37 INT209066 Slc11a1 Positive_regulation of Binding of TNF 1 0.01 1.11 0.24
38 INT226911 Slc11a1 Positive_regulation of Gene_expression of Il6 1 0.09 1.12 0.24
39 INT132447 TF Positive_regulation of IL6 1 0.09 1.1 0.23
40 INT295329 ecs Positive_regulation of TF 1 0.00 1.2 0.23
41 INT141623 OLR1 Positive_regulation of Gene_expression of TF 1 0.01 1.39 0.21
42 INT141625 Crp Positive_regulation of Gene_expression of TF 1 0.11 1.39 0.21
43 INT276241 Slc11a1 Positive_regulation of Gene_expression of Hand1 1 0.02 1.24 0.21
44 INT165335 Ltf Regulation of Mag 1 0.03 0.37 0.19
45 INT132457 Binding of TF and Gtf3a 1 0.01 0.64 0.17
46 INT132446 Binding of TF and COBRA1 1 0.01 0.63 0.17
47 INT178269 Slc11a2 Regulation of a 1 0.06 0.97 0.16
48 INT47965 Binding of TF and GORASP1 1 0.52 0.35 0.16
49 INT47964 Binding of REL and TF 1 0.52 0.35 0.16
50 INT238825 LTF Regulation of Localization of RBP4 1 0.05 1.08 0.16
51 INT226901 Slc11a1 Regulation of Hist1h3f 1 0.02 0.41 0.15
52 INT204159 Slc11a2 Regulation of Gene_expression of HAMP 1 0.11 1.08 0.14
53 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
54 INT75739 Ltf Negative_regulation of Il6 1 0.35 0.39 0.13
55 INT288701 Epas1 Regulation of Transcription of Slc11a2 1 0.29 0.38 0.13
56 INT310412 Binding of CP and TF 1 0.14 1.66 0.13
57 INT75738 Ltf Negative_regulation of Tnf 1 0.31 0.39 0.13
58 INT75737 Ltf Negative_regulation of Gene_expression of Il6 1 0.35 0.32 0.12
59 INT226899 Slc11a1 Positive_regulation of Localization of Gtf3a 1 0.00 0.54 0.11
60 INT226910 Slc11a1 Positive_regulation of Localization of Nfkb1 1 0.11 0.62 0.11
61 INT276495 TF Positive_regulation of F7 1 0.23 1.63 0.1
62 INT114414 TF Regulation of INS 1 0.18 0.09 0.09
63 INT276496 Binding of TF and F7 1 0.18 0.81 0.08
64 INT226912 Slc11a1 Positive_regulation of Localization of IL8 1 0.05 0.58 0.08
65 INT342288 Binding of CD4 and HFE 1 0.01 1.26 0.08
66 INT318387 Binding of Slc40a1 and Hrct1 1 0.02 0.88 0.08
67 INT226913 Slc11a1 Positive_regulation of Gene_expression of IL8 1 0.05 0.63 0.07
68 INT147112 LYZ Regulation of Binding of LTF 1 0.14 1.02 0.07
69 INT23749 Ltf Positive_regulation of Sct 1 0.02 0.33 0.06
70 INT338827 Binding of Slc40a1 and HAMP 1 0.00 0.27 0.05
71 INT326625 Binding of ALB and Trf 1 0.01 0.64 0.04
72 INT227072 Binding of LTF and PTPRC 1 0.00 0.51 0.04
73 INT226897 Binding of Slc11a1 and Tg(CAG-EGFP)D4Nagy 1 0.01 0.17 0.04
74 INT332906 Binding of PPARA and TF 1 0.03 0.1 0.04
75 INT220677 Binding of Mfi2 and Gtf3a 1 0.00 0.77 0.04
76 INT226905 Slc11a1 Regulation of Nfkb1 1 0.04 0.41 0.03
77 INT298053 Binding of Ltf and Bpifa2 1 0.01 0.58 0.03
78 INT238819 Binding of LTF and RBP4 1 0.04 0.26 0
79 INT238823 LTF Positive_regulation of GOPC 1 0.01 0.29 0
80 INT268199 Rab22a Regulation of Trf 1 0.11 0.17 0
81 INT255020 TF Positive_regulation of Binding of Gtf3a 1 0.00 0.06 0
82 INT255012 TF Positive_regulation of F10 1 0.06 0.06 0
83 INT338828 Binding of Trf and TMPRSS6 1 0.05 0.1 0
84 INT322607 Binding of RRM2 and TF 1 0.02 0.09 0
85 INT334280 NR2E3 Negative_regulation of Gene_expression of TF 1 0.02 0 0
86 INT272441 Binding of IFNA2 and Slc11a1 1 0.02 0.97 0
87 INT173378 Ns5atp9 Positive_regulation of Mfi2 1 0.00 0.43 0
88 INT276493 TFPI Regulation of TF 1 0.12 0.17 0
89 INT252791 Binding of IREB2 and TFRC 1 0.02 1.82 0
90 INT238822 TF Regulation of Localization of RBP4 1 0.14 0.28 0
91 INT221113 Slc11a1 Negative_regulation of Upk1b 1 0.19 0.37 0
92 INT232079 Regulation of Binding of CTBS and TF 1 0.00 0.25 0
93 INT209985 Binding of LRP1 and LTF 1 0.01 0 0
94 INT226896 Slc11a1 Positive_regulation of Binding of Nfkb1 1 0.11 0.08 0
95 INT322608 Binding of PAEP and TF 1 0.01 0.09 0
96 INT238818 LTF Positive_regulation of RBP4 1 0.06 0.29 0
97 INT238824 LTF Positive_regulation of Localization of RBP4 1 0.08 0.29 0
98 INT221114 Slc11a1 Negative_regulation of Upk1a 1 0.23 0.37 0
99 INT226909 Positive_regulation of Binding of Nfkb1 and Slc11a1 1 0.07 0.18 0
100 INT232078 Binding of CTBS and TF 1 0.00 0.49 0
101 INT238820 LTF Positive_regulation of Localization of GOPC 1 0.01 0.29 0
102 INT306943 TF Positive_regulation of Gene_expression of Trf 1 0.01 0.9 0
103 INT226898 Binding of Nfkb1 and Slc11a1 1 0.06 0.2 0
104 INT130417 TNFSF14 Positive_regulation of Gene_expression of TF 1 0.20 0 0
105 INT173381 Binding of Itgam and Mfi2 1 0.01 0 0
106 INT268181 Binding of Trf and Erc1 1 0.02 0.07 0
107 INT353797 Binding of Ldlr and Trf 1 0.04 0.19 0
108 INT279131 LTF Positive_regulation of CALR 1 0.03 2.39 0
109 INT268179 Negative_regulation of Binding of Trf and Erc1 1 0.03 0.07 0
110 INT242858 Binding of HFE and INS 1 0.06 1.64 0
111 INT183750 Binding of EPO and TF 1 0.42 1.21 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for iron ion transport. They are ordered first by their pain relevance and then by number of times they were reported in iron ion transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT13240 Gene_expression of TF 94 0.76 57.81 10.99
2 INT32344 Localization of LTF 30 0.80 15.28 10.09
3 INT58365 Gene_expression of LTF 51 0.78 44.14 7.25
4 INT88245 Gene_expression of Slc11a1 42 0.53 18.86 6.2
5 INT52904 Positive_regulation of LTF 21 0.67 15.58 5.78
6 INT22597 Positive_regulation of TF 43 0.68 27.27 5.17
7 INT59723 Binding of Slc40a1 5 0.35 1.31 5.17
8 INT44066 Gene_expression of Ltf 20 0.77 15.09 4.57
9 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56
10 INT11565 Gene_expression of Tf 24 0.68 5.89 4.36
11 INT57525 Negative_regulation of Ltf 9 0.50 4.2 4.03
12 INT209018 Positive_regulation of Slc11a1 11 0.55 7.12 3.83
13 INT132149 Positive_regulation of Gene_expression of LTF 10 0.70 11.5 3.14
14 INT46650 Localization of Trf 13 0.61 4.4 2.91
15 INT45253 Positive_regulation of Ltf 20 0.69 10.22 2.77
16 INT17033 Positive_regulation of Trf 21 0.62 11.76 2.68
17 INT100360 Negative_regulation of TF 19 0.42 10.43 2.68
18 INT24122 Positive_regulation of Ltf 9 0.61 5.33 2.44
19 INT209019 Localization of Slc11a1 12 0.33 4.33 2.33
20 INT2817 Localization of Ltf 10 0.80 4.13 2.32
21 INT23923 Regulation of Ltf 8 0.54 2.46 2.27
22 INT209027 Positive_regulation of Positive_regulation of Slc11a1 3 0.14 2.41 2.18
23 INT69080 Positive_regulation of Sfxn1 13 0.03 1.28 2.17
24 INT96841 Regulation of Slc11a1 9 0.36 6.83 2.14
25 INT52903 Positive_regulation of Localization of LTF 4 0.67 1.02 2.11
26 INT23748 Localization of Ltf 15 0.79 5.43 2.07
27 INT83329 Regulation of Gene_expression of Tf 4 0.16 1.83 1.93
28 INT36499 Negative_regulation of Tf 6 0.38 3.02 1.85
29 INT59722 Negative_regulation of Slc40a1 3 0.11 0.56 1.73
30 INT96842 Binding of Slc11a1 16 0.34 7.15 1.66
31 INT58456 Gene_expression of HFE 10 0.58 7.68 1.65
32 INT132882 Gene_expression of Slc40a1 4 0.17 1.35 1.6
33 INT194896 Gene_expression of Mfi2 14 0.15 6.65 1.59
34 INT54593 Positive_regulation of Gene_expression of TF 16 0.68 9.05 1.43
35 INT2818 Gene_expression of Ltf 6 0.70 2.87 1.4
36 INT16239 Negative_regulation of Trf 9 0.32 4.06 1.35
37 INT36500 Negative_regulation of Gene_expression of Tf 4 0.38 1.22 1.29
38 INT82345 Regulation of Slc40a1 2 0.23 0.33 1.28
39 INT132453 Binding of TF 31 0.36 12.98 1.22
40 INT36443 Regulation of Trf 4 0.61 1.65 1.18
41 INT769 Regulation of Tf 3 0.30 1 1.18
42 INT91106 Negative_regulation of LTF 9 0.51 5.73 1.09
43 INT58457 Positive_regulation of HFE 3 0.28 2.75 1.04
44 INT3568 Localization of Tf 4 0.62 1.27 1
45 INT147113 Binding of LTF 14 0.29 18.24 0.98
46 INT13241 Negative_regulation of Gene_expression of TF 7 0.57 3.03 0.93
47 INT132883 Gene_expression of Slc11a2 5 0.75 2.96 0.89
48 INT19637 Localization of TF 14 0.73 5.74 0.86
49 INT89368 Positive_regulation of Tf 7 0.34 3.62 0.83
50 INT297919 Negative_regulation of Gene_expression of LTF 2 0.09 3.27 0.79
51 INT28037 Negative_regulation of Ltf 3 0.51 1.87 0.72
52 INT297916 Positive_regulation of Binding of LTF 1 0.11 2.47 0.7
53 INT221108 Negative_regulation of Slc11a1 5 0.33 3.76 0.69
54 INT297924 Regulation of Binding of LTF 1 0.10 2.45 0.69
55 INT297920 Positive_regulation of Transcription of LTF 2 0.34 2.5 0.68
56 INT297922 Transcription of LTF 2 0.47 2.48 0.68
57 INT24735 Regulation of TF 10 0.44 5.55 0.65
58 INT103950 Positive_regulation of Negative_regulation of TF 1 0.14 0.17 0.63
59 INT45252 Positive_regulation of Localization of Ltf 2 0.50 1.47 0.62
60 INT168552 Protein_catabolism of Ltf 1 0.46 0.23 0.61
61 INT209023 Positive_regulation of Gene_expression of Slc11a1 3 0.22 1.19 0.6
62 INT57526 Regulation of Ltf 8 0.45 2.73 0.56
63 INT209015 Positive_regulation of Localization of Slc11a1 1 0.14 0.45 0.54
64 INT197370 Gene_expression of Sfxn1 1 0.01 0.05 0.54
65 INT209020 Negative_regulation of Gene_expression of Slc11a1 3 0.16 0.78 0.49
66 INT220664 Positive_regulation of Gene_expression of Mfi2 2 0.10 1.23 0.47
67 INT47987 Negative_regulation of Positive_regulation of TF 3 0.57 1.68 0.46
68 INT148882 Regulation of LTF 9 0.12 4.8 0.44
69 INT23247 Positive_regulation of Localization of Ltf 2 0.63 0.73 0.41
70 INT194168 Protein_catabolism of LTF 3 0.67 2.02 0.38
71 INT47973 Transcription of TF 3 0.70 0.65 0.38
72 INT47978 Positive_regulation of Transcription of TF 3 0.68 0.66 0.38
73 INT297921 Regulation of Gene_expression of LTF 2 0.10 3.11 0.37
74 INT130073 Regulation of Sfxn1 2 0.42 0.14 0.36
75 INT187778 Gene_expression of Slc11a1 12 0.33 7.37 0.35
76 INT46843 Binding of Trf 10 0.47 3.45 0.35
77 INT11941 Binding of Slc11a1 3 0.14 2.18 0.35
78 INT252053 Regulation of Localization of LTF 1 0.08 0 0.34
79 INT226881 Regulation of Positive_regulation of Slc11a1 1 0.09 0.95 0.32
80 INT71292 Binding of Tf 5 0.27 1.58 0.3
81 INT130074 Positive_regulation of Positive_regulation of Sfxn1 2 0.01 0.07 0.29
82 INT173117 Binding of Ltf 4 0.12 1.85 0.28
83 INT154074 Positive_regulation of Gene_expression of Tf 4 0.46 1.64 0.28
84 INT45236 Positive_regulation of Gene_expression of Trf 3 0.62 1.67 0.28
85 INT162252 Positive_regulation of Slc40a1 4 0.36 0.79 0.25
86 INT46846 Positive_regulation of Positive_regulation of Ltf 1 0.11 0.34 0.25
87 INT150594 Negative_regulation of HFE 1 0.00 0 0.2
88 INT141624 Phosphorylation of TF 1 0.34 1.34 0.19
89 INT288188 Negative_regulation of Mfi2 1 0.01 0.14 0.18
90 INT297914 Positive_regulation of Negative_regulation of LTF 1 0.11 1.76 0.18
91 INT47986 Negative_regulation of Transcription of TF 1 0.42 0.35 0.17
92 INT204148 Regulation of Gene_expression of Slc11a2 1 0.15 1.1 0.15
93 INT195743 Regulation of Binding of TF 2 0.09 0.88 0.14
94 INT354092 Positive_regulation of Positive_regulation of Trf 1 0.07 0.38 0.14
95 INT288681 Regulation of Transcription of Slc11a2 1 0.44 0.37 0.13
96 INT288683 Transcription of Slc11a2 1 0.69 0.37 0.13
97 INT242865 Binding of HFE 7 0.42 6.01 0.12
98 INT183042 Localization of HFE 2 0.56 1.35 0.12
99 INT288682 Binding of Slc11a2 1 0.47 0 0.12
100 INT173118 Negative_regulation of Binding of Ltf 1 0.11 0.2 0.12
101 INT204146 Localization of Slc40a1 1 0.05 0.99 0.11
102 INT204144 Negative_regulation of Localization of Slc40a1 1 0.03 0.99 0.11
103 INT318386 Negative_regulation of Gene_expression of Slc40a1 1 0.11 0.48 0.09
104 INT138005 Regulation of Positive_regulation of TF 1 0.44 0.56 0.09
105 INT61207 Regulation of Gene_expression of Trf 1 0.02 0.79 0.09
106 INT194166 Regulation of Regulation of LTF 1 0.07 0.57 0.09
107 INT122944 Positive_regulation of Positive_regulation of Ltf 1 0.17 0.89 0.08
108 INT220665 Negative_regulation of Gene_expression of Mfi2 1 0.01 0.78 0.08
109 INT157871 Negative_regulation of Gene_expression of Fth1 1 0.11 0.08 0.08
110 INT279438 Negative_regulation of Localization of Ltf 1 0.09 0.35 0.08
111 INT220660 Regulation of Mfi2 2 0.05 0.94 0.07
112 INT173392 Negative_regulation of Mfi2 1 0.04 0.22 0.07
113 INT157874 Gene_expression of Fth1 1 0.16 0.07 0.07
114 INT150703 Positive_regulation of Gene_expression of Ltf 1 0.08 1.83 0.06
115 INT252699 Gene_expression of IREB2 1 0.11 1.79 0.05
116 INT237126 Negative_regulation of Sfxn1 1 0.01 1.32 0.05
117 INT252720 Negative_regulation of IREB2 1 0.06 0.82 0.05
118 INT252724 Negative_regulation of Gene_expression of IREB2 1 0.06 0.89 0.05
119 INT220668 Binding of Mfi2 3 0.13 2.12 0.04
120 INT274763 Negative_regulation of Gene_expression of Trf 2 0.03 1.34 0.04
121 INT276426 Transcription of Trf 2 0.07 0.48 0.04
122 INT173391 Gene_expression of Mfi2 1 0.06 0.15 0.04
123 INT237128 Negative_regulation of Negative_regulation of Sfxn1 1 0.01 0.66 0.03
124 INT276494 Protein_catabolism of TF 1 0.97 0.65 0.03
125 INT183072 Positive_regulation of Localization of HFE 1 0.05 0.2 0.03
126 INT303110 Positive_regulation of Positive_regulation of LTF 1 0.04 0.45 0.03
127 INT214462 Positive_regulation of Mfi2 1 0.10 0.07 0.03
128 INT255015 Positive_regulation of Localization of TF 1 0.05 0.14 0.03
129 INT187781 Positive_regulation of Slc11a1 3 0.24 1.76 0
130 INT294978 Negative_regulation of Binding of TF 2 0.20 0.15 0
131 INT242866 Regulation of HFE 2 0.39 1.84 0
132 INT252722 Binding of IREB2 2 0.16 1.31 0
133 INT187780 Localization of Slc11a1 2 0.28 0.9 0
134 INT221110 Regulation of Regulation of Slc11a1 1 0.35 0.22 0
135 INT315631 Protein_catabolism of IREB2 1 0.44 0.4 0
136 INT262807 Positive_regulation of Transcription of Slc11a1 1 0.19 0.08 0
137 INT187779 Regulation of Slc11a1 1 0.10 0.75 0
138 INT102463 Negative_regulation of Regulation of Trf 1 0.17 0.08 0
139 INT102462 Regulation of Positive_regulation of Trf 1 0.18 0.08 0
140 INT187777 Positive_regulation of Localization of Slc11a1 1 0.19 0.27 0
141 INT262808 Transcription of Slc11a1 1 0.26 0.08 0
142 INT325826 Negative_regulation of Localization of Trf 1 0.14 0 0
143 INT268172 Phosphorylation of Trf 1 0.49 0 0
144 INT303111 Negative_regulation of Positive_regulation of LTF 1 0.03 0.13 0
145 INT284384 Positive_regulation of Binding of TF 1 0.04 0 0
146 INT128554 Regulation of Gene_expression of TF 1 0.40 0 0
147 INT268146 Regulation of Binding of Trf 1 0.24 0.05 0
148 INT315632 Positive_regulation of Protein_catabolism of IREB2 1 0.22 0.4 0
149 INT272440 Negative_regulation of Slc11a1 1 0.02 0.81 0
150 INT253284 Regulation of Gene_expression of Mfi2 1 0.09 0.15 0
151 INT226886 Regulation of Binding of Slc11a1 1 0.09 0.15 0
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