GO:0006833

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Name water transport
Categary Process
Go Slim No
Go Link GO:0006833
Unique Molecular Interactions 371
Total Molecular Interactions 477
Total Single Events 7391
Pain Genes Associated 29

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for water transport. They are ordered first by their pain relevance and then by number of times they were reported for water transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84
2 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
3 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56
4 INT334131 Acsm3 Positive_regulation of Mip 1 0.13 3.12 1.48
5 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
6 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
7 INT162419 Binding of Abpa and Cftr 1 0.04 1.66 1.19
8 INT65203 OPRL1 Negative_regulation of ADCY1 1 0.19 0 1.19
9 INT49955 OPRM1 Positive_regulation of ADCY1 1 0.21 0.31 1.19
10 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
11 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
12 INT65204 PNOC Negative_regulation of ADCY1 1 0.07 0 1.14
13 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09
14 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
15 INT63103 AVP Regulation of OXT 1 0.28 0.68 1.02
16 INT53052 ANTXRL Negative_regulation of Negative_regulation of ADCY1 1 0.01 0.66 0.99
17 INT128653 ITIH4 Regulation of Gene_expression of MIP 1 0.23 1.44 0.92
18 INT52114 Oprd1 Regulation of ADCY1 2 0.05 0.46 0.9
19 INT52390 OPRD1 Regulation of ADCY1 1 0.09 0.13 0.86
20 INT114324 RAF1 Positive_regulation of Phosphorylation of ADCY6 1 0.02 0.05 0.85
21 INT114323 Binding of ADCY6 and RAF1 1 0.02 0.05 0.85
22 INT80877 Negative_regulation of PCDHB17 Negative_regulation of ADCY1 1 0.01 0.08 0.84
23 INT80878 PCDHB17 Negative_regulation of ADCY1 1 0.01 0.08 0.84
24 INT19299 ANG Regulation of AVP 1 0.25 0 0.82
25 INT334130 Negative_regulation of Acsm3 Positive_regulation of Mip 1 0.12 1.48 0.81
26 INT250248 Binding of AQP4 and SLC1A3 1 0.11 1.55 0.77
27 INT334134 Acsm3 Positive_regulation of Gene_expression of Mip 1 0.13 1.4 0.77
28 INT65593 CALCA Negative_regulation of Positive_regulation of ADCY1 1 0.23 0.07 0.76
29 INT334153 Binding of AQP4 and CSF2 1 0.16 3 0.75
30 INT245572 Binding of AVPR2 and SPECC1 1 0.10 0.75 0.75
31 INT123869 Binding of GNAS and OPRK1 1 0.00 0.37 0.7
32 INT199395 Mip Positive_regulation of Positive_regulation of Trpv1 1 0.01 0.86 0.69
33 INT170832 Cftr Regulation of Scnn1a 2 0.16 1.2 0.67
34 INT74599 YY1 Negative_regulation of ADCY1 2 0.36 0.31 0.67
35 INT25957 Gabrg1 Regulation of Localization of AVP 1 0.01 0 0.62
36 INT250247 FCGR3A Negative_regulation of AQP4 1 0.01 0.87 0.62
37 INT42269 POMC Negative_regulation of Localization of AVP 1 0.09 0 0.61
38 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59
39 INT29847 INS Regulation of Localization of AVP 1 0.23 0.24 0.59
40 INT64036 Binding of AVP and HTR1A 1 0.40 0.36 0.57
41 INT94507 Tnf Positive_regulation of Gene_expression of AVP 1 0.39 0.98 0.57
42 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 1 0.00 0 0.56
43 INT170833 Cftr Negative_regulation of Slc10a2 1 0.47 0.31 0.56
44 INT169648 IGHG3 Regulation of AQP4 3 0.02 4.63 0.55
45 INT210830 OPRM1 Negative_regulation of ADCY1 1 0.00 0.06 0.55
46 INT32908 Binding of ADCY1 and Drd2 1 0.00 0 0.54
47 INT64744 OR5D2P Negative_regulation of ADCY1 1 0.00 0 0.54
48 INT129869 SERPINA6 Regulation of AVP 1 0.25 2.33 0.54
49 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53
50 INT69291 Cftr Positive_regulation of Localization of Slc4a8 1 0.04 0.38 0.51
51 INT117482 CFTR Negative_regulation of THRB 1 0.01 0.15 0.51
52 INT93265 Binding of ADCY1 and OPRL1 1 0.13 0.17 0.51
53 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5
54 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
55 INT161166 Binding of Aqp4 and Igh-6 1 0.03 2.58 0.49
56 INT89647 OPRM1 Regulation of ADCY1 1 0.09 0.09 0.47
57 INT19297 ANG Positive_regulation of AVP 1 0.28 0 0.46
58 INT341623 Binding of CFTR and CTRC 1 0.35 1.22 0.46
59 INT341624 Binding of CFTR and PRSS1 1 0.39 1.01 0.45
60 INT258584 ADORA3 Negative_regulation of ADCY1 1 0.02 0 0.44
61 INT111275 BRI3P1 Positive_regulation of Negative_regulation of ADCY1 1 0.06 0 0.44
62 INT89649 INSRR Regulation of ADCY1 1 0.00 0.07 0.44
63 INT111274 C2 Positive_regulation of Negative_regulation of ADCY1 1 0.14 0 0.44
64 INT73832 Pld1 Positive_regulation of ADCY1 1 0.00 0.16 0.44
65 INT157343 Binding of AQP4 and HLA-DPB1 1 0.30 0.89 0.43
66 INT335996 Mmp8 Regulation of Protein_catabolism of MIP 1 0.44 1.06 0.43
67 INT309157 Aqp1 Positive_regulation of Bdnf 1 0.00 0.74 0.42
68 INT126979 Penk Negative_regulation of Localization of AVP 1 0.00 0 0.41
69 INT68526 Binding of ADCY1 and DIO2 1 0.01 0.07 0.41
70 INT68527 Binding of ADCY1 and OPRD1 1 0.06 0.07 0.41
71 INT105170 OPRD1 Positive_regulation of Phosphorylation of ADCY1 1 0.08 0 0.41
72 INT52954 Binding of Pdpn and Flvcr2 1 0.05 0.42 0.41
73 INT11425 OR2A12 Positive_regulation of Negative_regulation of ADCY1 1 0.01 0 0.4
74 INT105169 RAF1 Regulation of Positive_regulation of ADCY1 1 0.12 0 0.4
75 INT124799 PRKCA Positive_regulation of Localization of ADCY6 1 0.19 0 0.4
76 INT7634 RFC1 Negative_regulation of Localization of AVP 1 0.46 0 0.39
77 INT250250 Gene_expression of AQP4 Positive_regulation of Gene_expression of SLC1A2 1 0.37 1.1 0.39
78 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35
79 INT250242 Binding of AQP4 and GOPC 1 0.06 0.39 0.35
80 INT84600 Binding of Avp and Aqp2 1 0.17 0 0.35
81 INT352547 Binding of CFTR and DMD 1 0.01 1.42 0.35
82 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32
83 INT308701 Binding of AQP4 and DDX41 1 0.15 3.53 0.32
84 INT12390 AVP Regulation of Localization of POMC 1 0.29 0.27 0.3
85 INT30706 Nppa Positive_regulation of Localization of AVP 1 0.78 0.45 0.3
86 INT139778 Binding of AQP1 and GBE1 1 0.00 0.22 0.3
87 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3
88 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3
89 INT89909 AVP Positive_regulation of Localization of POMC 1 0.44 0 0.29
90 INT89906 AVP Positive_regulation of Localization of GH1 1 0.14 0 0.29
91 INT89903 AVP Positive_regulation of Localization of PRL 1 0.40 0 0.29
92 INT339001 GSX1 Positive_regulation of ADCY1 1 0.01 0 0.29
93 INT141438 Gnai2 Positive_regulation of Localization of ADCY1 1 0.01 0.43 0.29
94 INT109711 Mip Positive_regulation of Rtcd1 1 0.00 0 0.29
95 INT310696 Tlr4 Positive_regulation of Positive_regulation of Cftr 1 0.16 0.74 0.28
96 INT210828 POMC Positive_regulation of ADCY1 1 0.03 0.34 0.28
97 INT196695 Prkaca Positive_regulation of CFTR 1 0.46 0.13 0.27
98 INT265831 BGN Positive_regulation of ADCY1 1 0.01 0.41 0.27
99 INT93952 CGA Positive_regulation of ADCY1 1 0.03 0 0.27
100 INT293118 Avp Regulation of Aqp2 1 0.04 0.7 0.27
101 INT274697 Binding of CFTR and Cftr 1 0.08 0.69 0.27
102 INT93953 Negative_regulation of CGA Positive_regulation of ADCY1 1 0.03 0 0.27
103 INT308708 DDX41 Regulation of AQP4 1 0.10 2.79 0.26
104 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26
105 INT223042 AR Positive_regulation of ADCY1 1 0.01 0.41 0.25
106 INT223036 SLURP1 Regulation of Positive_regulation of ADCY1 1 0.00 0.42 0.25
107 INT268768 Mip Regulation of Positive_regulation of Ccr1 1 0.44 0.83 0.23
108 INT34499 ADRB3 Positive_regulation of ADCY1 1 0.07 0.19 0.23
109 INT58305 AQP1 Regulation of Localization of TNF 1 0.10 0.16 0.22
110 INT58303 AQP1 Regulation of Gene_expression of IL1B 1 0.10 0.16 0.22
111 INT354544 Avp Positive_regulation of ADCY1 1 0.24 2.23 0.22
112 INT217349 Mip Positive_regulation of IL8 1 0.05 1.28 0.22
113 INT224130 Positive_regulation of Adora2a Positive_regulation of ADCY1 1 0.01 0.11 0.22
114 INT170834 Cftr Regulation of Slc10a2 1 0.58 0.37 0.22
115 INT87061 Binding of AVP and IL6 1 0.26 1.04 0.22
116 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21
117 INT7332 CALM3 Positive_regulation of ADCY1 1 0.46 0.13 0.21
118 INT52629 Binding of AVP and NMS 1 0.04 1.04 0.21
119 INT182634 Binding of CCR5 and MIP 2 0.39 1.29 0.2
120 INT224133 Negative_regulation of Adora2b Positive_regulation of ADCY1 1 0.01 0.1 0.2
121 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2
122 INT3592 INS Positive_regulation of AVP 1 0.05 0.28 0.2
123 INT3591 Negative_regulation of INS Positive_regulation of AVP 1 0.04 0.28 0.2
124 INT224134 Adora2b Positive_regulation of ADCY1 1 0.01 0.1 0.2
125 INT196610 IFNG Negative_regulation of CFTR 1 0.17 0.21 0.19
126 INT25495 AVP Positive_regulation of CRH 1 0.14 0 0.19
127 INT25497 AVP Positive_regulation of Localization of CRH 1 0.14 0 0.19
128 INT216841 TCIRG1 Negative_regulation of ADCY1 1 0.01 0.35 0.18
129 INT267660 CFTR Regulation of Gene_expression of P2RX2 1 0.25 0.51 0.18
130 INT87060 IL6 Positive_regulation of Localization of AVP 1 0.59 1.01 0.18
131 INT216842 ATP6V0A1 Negative_regulation of ADCY1 1 0.01 0.35 0.18
132 INT74600 Negative_regulation of YY1 Negative_regulation of ADCY1 1 0.36 0.25 0.17
133 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17
134 INT148563 Ngf Positive_regulation of GNAS 1 0.06 0.07 0.16
135 INT196606 IFNG Positive_regulation of CFTR 1 0.16 0.45 0.16
136 INT250241 SLC1A3 Positive_regulation of AQP4 1 0.13 0.21 0.16
137 INT127206 Negative_regulation of Cftr Negative_regulation of Positive_regulation of Mcf2l 1 0.16 0.62 0.16
138 INT250246 SLC1A2 Positive_regulation of AQP4 1 0.13 0.22 0.16
139 INT106641 Binding of AVP and OXTR 1 0.22 0.47 0.16
140 INT30705 Nppa Negative_regulation of Localization of AVP 1 0.48 0.22 0.15
141 INT261521 Binding of ADCY1 and GLUL 1 0.01 0.09 0.15
142 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15
143 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
144 INT241772 AVP Positive_regulation of ADCY1 1 0.09 1.08 0.15
145 INT77122 WDTC1 Positive_regulation of Negative_regulation of ADCY1 1 0.06 0.39 0.15
146 INT293124 Agtr1a Regulation of Gene_expression of Aqp2 1 0.17 0.36 0.14
147 INT327829 Aqp1 Regulation of Binding of Csf2 1 0.11 1 0.14
148 INT26190 PTAFR Regulation of AVP 1 0.16 0 0.14
149 INT196608 TNF Negative_regulation of CFTR 1 0.16 0.11 0.14
150 INT293117 Agt Regulation of Gene_expression of Aqp2 1 0.23 0.36 0.14
151 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14
152 INT308709 Positive_regulation of Binding of AQP4 and DDX41 1 0.18 1.19 0.14
153 INT129868 Regulation of SERPINA6 Regulation of AVP 1 0.25 0.59 0.14
154 INT61998 GNPTAB Positive_regulation of ADCY1 1 0.03 0 0.13
155 INT241777 Negative_regulation of Binding of AVP and TRGV9 1 0.10 0.75 0.13
156 INT344314 PDPN Positive_regulation of Phosphorylation of MAPK8 1 0.35 0.67 0.13
157 INT52711 BSG Regulation of ADCY1 1 0.01 0.1 0.12
158 INT141426 ANTXRL Negative_regulation of ADCY1 1 0.00 0.41 0.11
159 INT255811 Binding of GNAS and MAPT 1 0.00 0.67 0.11
160 INT57220 Positive_regulation of ATF3 Positive_regulation of PRKACA 1 0.17 0.1 0.09
161 INT260944 Mapk14 Positive_regulation of Transcription of Aqp3 1 0.29 0.21 0.09
162 INT57214 ATF3 Positive_regulation of PRKACA 1 0.17 0.1 0.09
163 INT72302 Regulation of ADRA2C Regulation of ADCY1 1 0.02 0.14 0.09
164 INT260947 Mapk14 Positive_regulation of Aqp3 1 0.29 0.21 0.09
165 INT72304 ADRA2C Regulation of ADCY1 1 0.02 0.14 0.09
166 INT260945 Mapk14 Positive_regulation of Gene_expression of Aqp3 1 0.29 0.21 0.09
167 INT238472 Binding of AVP and POR 1 0.02 0.85 0.09
168 INT235964 Binding of Atp9a and Aqp4 1 0.01 0.55 0.08
169 INT250244 Binding of AQP4 and Positive_regulation of SLC1A3 1 0.14 0.69 0.08
170 INT234802 Binding of AQP2 and AVPR2 2 0.15 0.84 0.07
171 INT283126 Dag1 Positive_regulation of Localization of Aqp4 1 0.47 0.2 0.07
172 INT172381 AVP Positive_regulation of Localization of EDN1 1 0.01 0.34 0.07
173 INT216545 Gene_expression of Cftr Negative_regulation of Kcnma1 1 0.00 0.59 0.06
174 INT235963 Snta1 Regulation of Gene_expression of Aqp4 1 0.41 0.23 0.05
175 INT293122 Avp Regulation of Gene_expression of Aqp2 1 0.04 0.81 0.05
176 INT247843 Narfl Regulation of Aqp4 1 0.04 1.07 0.04
177 INT344312 PDPN Positive_regulation of ITK 1 0.05 0.26 0.04
178 INT247855 Positive_regulation of Narfl Regulation of Aqp4 1 0.04 2.93 0.04
179 INT196639 Negative_regulation of NA Negative_regulation of Transcription of CFTR 1 0.02 0.63 0.03
180 INT293559 Binding of CALM1 and Aqp6 1 0.01 0 0.03
181 INT213585 Binding of CFTR and FLNA 1 0.14 0.11 0.03
182 INT344317 PDPN Negative_regulation of VEGFA 1 0.08 0.67 0.03
183 INT310694 Tlr4 Positive_regulation of Cftr 1 0.16 0.34 0.03
184 INT344308 Positive_regulation of PDPN Negative_regulation of VEGFA 1 0.09 0.24 0.03
185 INT308747 Binding of Cftr and Prkag1 1 0.02 0 0
186 INT241775 AVP Positive_regulation of Gene_expression of AQP2 1 0.08 0.17 0
187 INT297693 Binding of Aqp2 and Fut1 1 0.03 0 0
188 INT117419 Binding of AVPR2 and TSKU 1 0.39 0.21 0
189 INT327830 Alms1 Positive_regulation of Aqp4 1 0.03 0.15 0
190 INT249538 Binding of BDNF and GNAS 1 0.08 0 0
191 INT225969 Binding of Aqp4 and Nefl 1 0.07 0.3 0
192 INT6756 Binding of AVP and POMC 1 0.39 0.51 0
193 INT179302 Gene_expression of GNAS Negative_regulation of CA2 1 0.01 0 0
194 INT241779 AVP Positive_regulation of TRGV9 1 0.17 0.48 0
195 INT344315 MAPK8 Positive_regulation of Negative_regulation of PDPN 1 0.35 0.56 0
196 INT299232 Onc1 Regulation of Gene_expression of Aqp4 1 0.01 0.43 0
197 INT347723 Binding of Aqp4 and Tmed4 1 0.27 0 0
198 INT241769 AVP Regulation of Binding of AVPR1A 1 0.11 0.49 0
199 INT241771 Binding of AVP and AVPR1B 1 0.04 0.49 0
200 INT308706 Binding of AQP4 and M1 1 0.06 0.86 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for water transport. They are ordered first by their pain relevance and then by number of times they were reported in water transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT214 Localization of AVP 370 0.81 208.51 91.09
2 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96
3 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9
4 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41
5 INT685 Regulation of AVP 124 0.62 34.9 39.91
6 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23
7 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63
8 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
9 INT140413 Gene_expression of AQP4 113 0.78 139.25 25.53
10 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91
11 INT103842 Gene_expression of Cftr 53 0.78 59.59 21.82
12 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84
13 INT109650 Gene_expression of Aqp4 87 0.78 51.52 20.72
14 INT213 Negative_regulation of Localization of AVP 46 0.59 19.78 16.79
15 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64
16 INT12617 Regulation of ADCY1 41 0.61 7.38 15.94
17 INT84307 Binding of Cftr 31 0.47 26.19 12.8
18 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23
19 INT11429 Gene_expression of ADCY1 26 0.74 5.89 11.93
20 INT40486 Positive_regulation of Positive_regulation of ADCY1 20 0.48 4.29 11.33
21 INT109651 Negative_regulation of Aqp4 23 0.53 8.5 10.7
22 INT69867 Gene_expression of Mip 36 0.75 24.54 10.38
23 INT83292 Gene_expression of MIP 35 0.75 25.22 10.14
24 INT12620 Negative_regulation of Negative_regulation of ADCY1 16 0.44 2.98 10.1
25 INT119892 Gene_expression of Cftr 54 0.77 23.76 9.73
26 INT77282 Positive_regulation of Cftr 23 0.69 21.8 9.65
27 INT101891 Negative_regulation of Cftr 25 0.58 24.09 9.55
28 INT250282 Negative_regulation of AQP4 32 0.54 32.96 9.07
29 INT684 Binding of AVP 38 0.48 13.9 8.85
30 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62
31 INT54681 Negative_regulation of Positive_regulation of ADCY1 16 0.38 2.7 8.14
32 INT157959 Binding of AQP4 32 0.48 43.44 7.44
33 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4
34 INT327801 Positive_regulation of Gene_expression of Aqp2 6 0.44 7.67 7.24
35 INT138802 Gene_expression of CFTR 36 0.70 18.8 7.02
36 INT69289 Negative_regulation of Cftr 44 0.57 13.28 6.97
37 INT86119 Regulation of Cftr 13 0.45 14.08 5.75
38 INT155348 Positive_regulation of Aqp4 14 0.63 9.92 5.53
39 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
40 INT80881 Phosphorylation of ADCY1 7 0.69 1.22 5.29
41 INT151102 Positive_regulation of CFTR 22 0.61 15.27 5.12
42 INT89114 Binding of Cftr 13 0.37 11.29 4.99
43 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
44 INT52952 Binding of Pdpn 8 0.13 3.57 4.79
45 INT170757 Positive_regulation of Gene_expression of Cftr 3 0.51 11.41 4.75
46 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
47 INT169756 Binding of CFTR 9 0.35 9.65 4.55
48 INT14574 Positive_regulation of Negative_regulation of ADCY1 9 0.66 2.45 4.39
49 INT143337 Binding of Aqp4 30 0.40 23.73 4.24
50 INT160023 Regulation of Aqp4 9 0.45 8.41 4.19
51 INT48993 Positive_regulation of Cftr 17 0.57 6.02 4.12
52 INT19301 Regulation of Regulation of AVP 9 0.45 3.15 4.09
53 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03
54 INT89113 Regulation of Cftr 11 0.62 6.83 4.01
55 INT169748 Positive_regulation of Gene_expression of Aqp4 38 0.69 34.29 3.79
56 INT151099 Negative_regulation of CFTR 12 0.59 10.28 3.79
57 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77
58 INT225965 Localization of Aqp4 26 0.81 18.85 3.75
59 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
60 INT87408 Negative_regulation of ADCY2 3 0.01 0.1 3.68
61 INT130836 Transcription of Aqp4 6 0.72 5.93 3.52
62 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
63 INT156132 Gene_expression of Aqp9 26 0.49 14.33 3.48
64 INT87281 Localization of ADCY1 7 0.64 1.84 3.42
65 INT130835 Positive_regulation of Transcription of Aqp4 3 0.68 4.5 3.28
66 INT165821 Positive_regulation of Aqp4 27 0.70 24.37 3.22
67 INT13179 Regulation of Positive_regulation of ADCY1 5 0.34 0.89 3.08
68 INT157960 Regulation of AQP4 11 0.48 21.36 3.06
69 INT59309 Negative_regulation of Gene_expression of ADCY1 3 0.42 1.04 2.98
70 INT155349 Positive_regulation of Gene_expression of Aqp4 8 0.70 6.26 2.94
71 INT152961 Negative_regulation of Gene_expression of Aqp4 13 0.59 10.01 2.92
72 INT69641 Positive_regulation of ADCY2 5 0.32 0.18 2.87
73 INT169747 Localization of AQP4 17 0.75 16.64 2.79
74 INT30815 Binding of ADCY1 7 0.36 0.21 2.79
75 INT82885 Gene_expression of Mip 7 0.65 7.89 2.76
76 INT10848 Negative_regulation of Gene_expression of AVP 13 0.59 6.76 2.71
77 INT80884 Positive_regulation of Phosphorylation of ADCY1 4 0.43 0.24 2.64
78 INT86713 Positive_regulation of Mip 10 0.67 6.44 2.63
79 INT11426 Positive_regulation of Gene_expression of ADCY1 5 0.29 0.68 2.63
80 INT84599 Gene_expression of Aqp2 31 0.77 22.58 2.54
81 INT104563 Localization of Aqp4 10 0.73 7.82 2.54
82 INT69290 Localization of Cftr 11 0.75 3.69 2.52
83 INT262474 Gene_expression of Aqp6 26 0.77 2.08 2.49
84 INT140414 Positive_regulation of AQP4 25 0.64 23.43 2.47
85 INT46159 Positive_regulation of Positive_regulation of AVP 4 0.50 1.24 2.45
86 INT225966 Regulation of Gene_expression of Aqp4 18 0.62 20.39 2.3
87 INT86315 Transcription of Cftr 7 0.53 4.24 2.3
88 INT202522 Negative_regulation of Gene_expression of Cftr 11 0.57 5.9 2.24
89 INT83294 Regulation of MIP 4 0.60 3.91 2.21
90 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15
91 INT141721 Binding of Aqp1 5 0.37 1.77 2.15
92 INT46160 Regulation of Positive_regulation of AVP 4 0.53 0.99 2.14
93 INT203308 Regulation of Aqp1 4 0.48 2.59 2.13
94 INT179311 Transcription of GNAS 2 0.10 0.67 2.08
95 INT155344 Phosphorylation of Aqp4 1 0.82 4 2.05
96 INT108903 Negative_regulation of GNAS 7 0.57 1.58 2.04
97 INT166710 Positive_regulation of Gene_expression of CFTR 9 0.46 3.72 2.03
98 INT83293 Negative_regulation of MIP 2 0.41 4.12 2.02
99 INT104564 Gene_expression of Aqp3 8 0.65 4.92 1.99
100 INT140171 Binding of Aqp4 7 0.36 11.63 1.98
101 INT119891 Regulation of Gene_expression of Cftr 4 0.59 2.67 1.98
102 INT7375 Negative_regulation of Positive_regulation of AVP 6 0.43 0.37 1.97
103 INT82886 Positive_regulation of Mip 7 0.49 3.61 1.89
104 INT151101 Regulation of CFTR 4 0.62 3.69 1.89
105 INT250272 Positive_regulation of Gene_expression of AQP4 11 0.54 9.79 1.85
106 INT112971 Positive_regulation of Gene_expression of MIP 3 0.49 5.24 1.82
107 INT91336 Localization of MIP 5 0.78 2.97 1.79
108 INT83291 Regulation of Gene_expression of MIP 2 0.60 2 1.79
109 INT84595 Negative_regulation of Aqp2 11 0.58 4.88 1.78
110 INT210590 Positive_regulation of Gene_expression of Mip 10 0.67 8.09 1.68
111 INT84308 Localization of Cftr 12 0.75 6.16 1.65
112 INT23176 Gene_expression of Pdpn 6 0.75 4.06 1.65
113 INT87289 Positive_regulation of Localization of ADCY1 3 0.43 0.36 1.65
114 INT80890 Negative_regulation of Phosphorylation of ADCY1 2 0.36 0.24 1.57
115 INT72310 Regulation of Regulation of ADCY1 6 0.24 1.24 1.55
116 INT156133 Regulation of Gene_expression of Aqp2 4 0.39 1.43 1.53
117 INT164480 Negative_regulation of Gene_expression of Aqp4 14 0.58 10.84 1.52
118 INT121347 Binding of GNAS 8 0.13 3.99 1.47
119 INT10852 Transcription of AVP 3 0.69 1.75 1.41
120 INT211054 Positive_regulation of AQP1 3 0.33 4.53 1.41
121 INT45390 Negative_regulation of Mip 2 0.20 0.21 1.41
122 INT162308 Phosphorylation of GNAS 3 0.01 1.71 1.4
123 INT108281 Negative_regulation of Binding of Cftr 4 0.43 3.1 1.38
124 INT327824 Positive_regulation of Gene_expression of Aqp1 4 0.67 5.4 1.37
125 INT155345 Negative_regulation of Phosphorylation of Aqp4 1 0.43 2.86 1.37
126 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
127 INT152964 Regulation of Gene_expression of Aqp4 3 0.56 4.18 1.34
128 INT69863 Binding of Mip 7 0.36 4.54 1.33
129 INT148562 Positive_regulation of GNAS 13 0.16 5.31 1.32
130 INT139625 Regulation of Gene_expression of Cftr 5 0.50 3.59 1.32
131 INT32101 Regulation of Mip 3 0.26 0.89 1.31
132 INT80887 Negative_regulation of Regulation of ADCY1 3 0.35 0.1 1.26
133 INT100328 Gene_expression of AQP2 6 0.75 2.41 1.21
134 INT196675 Localization of CFTR 4 0.64 1.95 1.19
135 INT75891 Regulation of ADCY2 3 0.06 0.06 1.17
136 INT289973 Negative_regulation of Gene_expression of MIP 2 0.41 2.69 1.15
137 INT79557 Localization of Aqp2 5 0.73 2 1.13
138 INT268763 Negative_regulation of Mip 3 0.41 2.61 1.12
139 INT114326 Phosphorylation of ADCY6 2 0.70 0.05 1.11
140 INT235939 Gene_expression of Aqp5 8 0.45 4.7 1.06
141 INT124810 Gene_expression of ADCY6 6 0.65 0 1.06
142 INT72868 Transcription of ADCY1 4 0.57 0.69 1.04
143 INT202378 Transcription of Aqp4 5 0.65 1.7 1.02
144 INT166889 Positive_regulation of Gene_expression of AQP1 10 0.70 6.43 0.99
145 INT84597 Transcription of Aqp2 3 0.55 2.11 0.98
146 INT101050 Localization of Mip 4 0.78 1.9 0.93
147 INT183362 Regulation of AQP1 3 0.23 1.49 0.92
148 INT80871 Negative_regulation of Binding of ADCY1 1 0.03 0.1 0.91
149 INT25539 Regulation of Gene_expression of AVP 9 0.45 2.74 0.89
150 INT84598 Regulation of Aqp2 13 0.45 4.28 0.86
151 INT51704 Phosphorylation of AVP 2 0.79 0.33 0.86
152 INT51703 Positive_regulation of Phosphorylation of AVP 1 0.49 0.09 0.86
153 INT86314 Regulation of Transcription of Cftr 2 0.33 1.81 0.83
154 INT108348 Positive_regulation of Aqp2 10 0.68 4.94 0.82
155 INT61290 Regulation of Phosphorylation of CFTR 1 0.44 0.25 0.81
156 INT274693 Positive_regulation of Gene_expression of Cftr 6 0.49 2.93 0.8
157 INT61291 Phosphorylation of CFTR 1 0.80 0.25 0.8
158 INT124814 Localization of ADCY6 1 0.65 0 0.78
159 INT251679 Negative_regulation of Gene_expression of AQP4 2 0.38 10.37 0.77
160 INT149604 Regulation of Negative_regulation of AVP 2 0.44 0.49 0.77
161 INT235953 Regulation of Binding of Aqp4 4 0.45 4.4 0.76
162 INT235951 Positive_regulation of Positive_regulation of Aqp4 4 0.57 5.13 0.75
163 INT67252 Regulation of Pdpn 1 0.00 0.9 0.74
164 INT196682 Negative_regulation of Gene_expression of CFTR 6 0.34 1.96 0.73
165 INT149238 Positive_regulation of Gene_expression of Aqp2 5 0.66 3.07 0.73
166 INT124813 Negative_regulation of ADCY6 1 0.37 0 0.73
167 INT124811 Positive_regulation of Negative_regulation of ADCY6 1 0.40 0 0.73
168 INT151100 Negative_regulation of Positive_regulation of CFTR 1 0.43 1.11 0.73
169 INT327798 Transcription of Aqp2 1 0.34 1.02 0.72
170 INT241788 Positive_regulation of Gene_expression of AQP2 3 0.67 1.26 0.7
171 INT112326 Binding of Aqp2 3 0.11 1.01 0.69
172 INT202374 Negative_regulation of Transcription of Aqp4 2 0.37 1.34 0.69
173 INT127204 Negative_regulation of Positive_regulation of Cftr 1 0.43 1.9 0.69
174 INT334126 Positive_regulation of Positive_regulation of Mip 1 0.20 1.65 0.67
175 INT215828 Regulation of Binding of Cftr 2 0.33 1.56 0.66
176 INT353152 Localization of PRKACA 1 0.01 1.15 0.66
177 INT52951 Negative_regulation of Binding of Pdpn 1 0.16 0.63 0.66
178 INT103841 Negative_regulation of Gene_expression of Cftr 3 0.43 1.93 0.63
179 INT151098 Positive_regulation of Positive_regulation of CFTR 2 0.50 0.9 0.63
180 INT327779 Regulation of Gene_expression of AQP4 5 0.48 4.5 0.6
181 INT84596 Negative_regulation of Gene_expression of Aqp2 3 0.58 8.49 0.6
182 INT170759 Positive_regulation of Binding of Cftr 2 0.50 1.82 0.6
183 INT91332 Regulation of Localization of MIP 1 0.44 0.75 0.6
184 INT249551 Negative_regulation of Transcription of GNAS 1 0.06 0.16 0.6
185 INT127930 Gene_expression of ADCY2 6 0.11 0.1 0.59
186 INT84594 Negative_regulation of Transcription of Aqp2 1 0.43 0 0.59
187 INT165848 Protein_catabolism of ADCY1 1 0.25 0.28 0.57
188 INT100322 Localization of AQP2 5 0.80 0.56 0.56
189 INT210075 Positive_regulation of MIP 3 0.67 0.98 0.56
190 INT165845 Positive_regulation of Transcription of ADCY1 1 0.26 0.36 0.55
191 INT348872 Positive_regulation of Regulation of Cftr 1 0.34 1.3 0.55
192 INT139780 Binding of AQP1 7 0.32 4.62 0.54
193 INT6567 Positive_regulation of Regulation of AVP 2 0.67 0.93 0.51
194 INT268755 Negative_regulation of Gene_expression of Mip 1 0.41 1.73 0.51
195 INT110905 Regulation of Negative_regulation of ADCY1 1 0.59 0 0.48
196 INT293553 Binding of Aqp6 2 0.36 0.31 0.46
197 INT19592 Localization of AQP1 4 0.81 1.09 0.44
198 INT327786 Negative_regulation of Gene_expression of AQP1 3 0.29 4.21 0.44
199 INT183187 Transcription of Mip 2 0.69 0.69 0.43
200 INT111869 Protein_catabolism of AVP 3 0.64 0.63 0.42
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