GO:0006855

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Name drug transmembrane transport
Categary Process
Go Slim No
Go Link GO:0006855
Unique Molecular Interactions 54
Total Molecular Interactions 56
Total Single Events 1056
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for drug transmembrane transport. They are ordered first by their pain relevance and then by number of times they were reported for drug transmembrane transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT96008 Binding of KNG1 and EBP 1 0.01 0.15 0.88
2 INT120293 RYBP Positive_regulation of Abcc2 1 0.04 0.14 0.86
3 INT154439 Ufm1 Positive_regulation of Gene_expression of Abcb1a 1 0.00 0 0.85
4 INT155220 ABCG2 Positive_regulation of Abcc2 1 0.23 0.54 0.76
5 INT120294 RYBP Positive_regulation of Positive_regulation of Abcc2 1 0.02 0.15 0.61
6 INT106374 Olr833 Negative_regulation of Abcb1a 1 0.00 0 0.56
7 INT145726 Binding of Abcb1a and Alms1 1 0.32 0.48 0.56
8 INT130312 Ccl4 Negative_regulation of Abcc3 1 0.33 0.28 0.48
9 INT130310 Ccl4 Positive_regulation of Abcc2 1 0.44 0.28 0.47
10 INT130311 Ccl4 Positive_regulation of Abcc1 1 0.47 0.28 0.47
11 INT262220 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Abcc2 1 0.14 0.25 0.44
12 INT146087 Abcb1b Regulation of Binding of Abcb1a 1 0.49 0.09 0.34
13 INT146088 Abcb1b Regulation of Abcb1a 1 0.49 0.09 0.34
14 INT138721 Abcc1 Regulation of Gene_expression of Abcc4 1 0.50 0 0.31
15 INT133325 Mod2 Negative_regulation of Gene_expression of Abcb1a 1 0.01 0.18 0.31
16 INT262202 Nr1i2 Regulation of Abcc2 1 0.19 0.12 0.25
17 INT262152 Nr1h4 Regulation of Abcc2 1 0.07 0.12 0.25
18 INT143809 Negative_regulation of Abcc2 Positive_regulation of Positive_regulation of H2-M3 1 0.04 0 0.25
19 INT262178 Binding of Nr1i2 and Abcb1b 1 0.07 1.68 0.21
20 INT112781 Abcc1 Regulation of Abcb1b 1 0.25 0 0.21
21 INT121382 Casr Positive_regulation of Abcc3 1 0.32 0.25 0.19
22 INT121381 Casr Positive_regulation of Positive_regulation of Abcc3 1 0.30 0.25 0.19
23 INT138426 Abcb1b Regulation of Abcg2 1 0.29 0 0.17
24 INT138427 Abcc2 Regulation of Abcg2 1 0.30 0 0.17
25 INT262148 Positive_regulation of Nr1i2 Positive_regulation of Abcb1b 1 0.09 0.69 0.12
26 INT100479 Binding of Abcb1b and Camk1d 1 0.44 0 0.12
27 INT159274 Tsiq1 Positive_regulation of Abcb1a 1 0.00 0.14 0.07
28 INT155789 Binding of SGCG and SLC22A5 1 0.40 0 0.06
29 INT241536 Binding of Abcb1b and Abcg2 1 0.10 0.17 0.04
30 INT321530 Ubp1 Regulation of Abcb1b 1 0.43 0.06 0
31 INT277863 Binding of ERBB2 and Abcc3 1 0.01 0.28 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for drug transmembrane transport. They are ordered first by their pain relevance and then by number of times they were reported in drug transmembrane transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT90300 Gene_expression of Abcb1a 56 0.78 11.05 22.89
2 INT73362 Negative_regulation of Abcb1a 46 0.59 8.78 17.81
3 INT83682 Positive_regulation of Abcb1a 22 0.68 3.3 15.6
4 INT7776 Gene_expression of Abcb1b 63 0.75 21.35 14.92
5 INT104502 Gene_expression of Abcc2 26 0.78 8.37 9.65
6 INT80981 Regulation of Abcb1a 19 0.62 1.86 7.2
7 INT120286 Positive_regulation of Abcc2 11 0.70 4.71 6.2
8 INT54617 Positive_regulation of Gene_expression of Abcb1b 22 0.67 9.8 5.34
9 INT119909 Binding of Abcb1a 10 0.36 0.76 5.07
10 INT110202 Positive_regulation of Gene_expression of Abcb1a 13 0.67 2.08 5.01
11 INT130300 Gene_expression of Abcc3 14 0.70 5.34 4.96
12 INT56122 Positive_regulation of Abcc3 7 0.47 2.25 4.9
13 INT106131 Negative_regulation of Abcc3 8 0.58 3.17 4.86
14 INT60957 Negative_regulation of Abcb1b 18 0.57 6 4.73
15 INT80983 Regulation of Abcb1b 16 0.60 1.95 4.32
16 INT117828 Regulation of Gene_expression of Abcb1b 7 0.60 1.8 3.76
17 INT130295 Gene_expression of Abcg2 21 0.75 9.75 3.42
18 INT119238 Positive_regulation of Positive_regulation of Abcb1a 5 0.40 1.14 3.09
19 INT147159 Regulation of Gene_expression of Abcc3 4 0.55 2.96 2.97
20 INT131124 Localization of Abcc3 4 0.75 0.48 2.73
21 INT90299 Negative_regulation of Gene_expression of Abcb1a 4 0.43 0.54 2.65
22 INT40315 Gene_expression of Abcc1 10 0.76 5.66 2.53
23 INT131332 Negative_regulation of Gene_expression of Abcc2 7 0.58 1.25 2.35
24 INT135396 Regulation of Gene_expression of Abcb1a 7 0.60 0.69 2.28
25 INT60956 Binding of Abcb1b 8 0.47 2.49 2.09
26 INT112779 Positive_regulation of Abcc1 2 0.50 0.63 1.95
27 INT145075 Localization of SLC22A5 1 0.08 0.18 1.75
28 INT143807 Negative_regulation of Abcc2 4 0.58 0.93 1.65
29 INT147157 Positive_regulation of Abcc2 2 0.39 0.85 1.64
30 INT120288 Regulation of Gene_expression of Abcc2 5 0.44 1.3 1.52
31 INT78352 Localization of Abcb1a 4 0.68 1.44 1.52
32 INT110555 Localization of Abcc2 1 0.69 0 1.47
33 INT110556 Negative_regulation of Localization of Abcc2 1 0.39 0 1.47
34 INT145076 Gene_expression of SLC22A5 4 0.68 1.87 1.46
35 INT122407 Gene_expression of Abcc4 4 0.70 0.56 1.41
36 INT165690 Localization of Abcc2 4 0.79 1.31 1.38
37 INT145074 Binding of SLC22A5 3 0.37 1.56 1.29
38 INT130296 Positive_regulation of Abcc4 2 0.63 0.49 1.28
39 INT164325 Negative_regulation of Abcg2 6 0.39 1.88 1.2
40 INT134506 Negative_regulation of Abcc2 2 0.41 0.06 1.17
41 INT147162 Positive_regulation of Abcb1b 13 0.57 7.29 1.15
42 INT164322 Transcription of Abcg2 5 0.50 1.57 1.13
43 INT164323 Negative_regulation of Transcription of Abcg2 1 0.21 1.38 1.13
44 INT145077 Regulation of SLC22A5 2 0.19 3 1.1
45 INT120287 Regulation of Abcc2 2 0.24 0.81 1.06
46 INT145443 Positive_regulation of Positive_regulation of Abcc2 1 0.07 0.93 1.06
47 INT130301 Positive_regulation of Gene_expression of Abcc3 2 0.63 0.52 1
48 INT164324 Negative_regulation of Gene_expression of Abcg2 4 0.45 1.03 0.99
49 INT130297 Positive_regulation of Gene_expression of Abcc1 3 0.56 1.06 0.97
50 INT130299 Gene_expression of Abcc2 2 0.58 0.61 0.95
51 INT158436 Transcription of Abcc2 4 0.47 0.15 0.94
52 INT135398 Transcription of Abcb1a 2 0.55 1.53 0.89
53 INT155791 Transcription of SLC22A5 1 0.53 0 0.88
54 INT96012 Gene_expression of EBP 3 0.67 0.8 0.85
55 INT147164 Regulation of Abcg2 1 0.60 0.3 0.85
56 INT135399 Regulation of Positive_regulation of Abcb1a 1 0.49 0 0.73
57 INT134505 Positive_regulation of Gene_expression of Abcc2 4 0.69 1.81 0.71
58 INT135397 Positive_regulation of Regulation of Abcb1a 1 0.37 0 0.71
59 INT140711 Positive_regulation of EBP 1 0.29 0.72 0.68
60 INT147160 Transcription of Abcc3 2 0.42 0.95 0.66
61 INT130304 Positive_regulation of Gene_expression of Abcc2 1 0.38 0.21 0.46
62 INT133322 Positive_regulation of Localization of Abcb1a 1 0.14 0.41 0.44
63 INT133324 Negative_regulation of Localization of Abcb1a 1 0.12 0.41 0.44
64 INT302180 Positive_regulation of Gene_expression of Abcg2 6 0.61 3.13 0.43
65 INT130298 Negative_regulation of Positive_regulation of Abcc4 1 0.53 0.18 0.41
66 INT130303 Negative_regulation of Abcc4 1 0.39 0.18 0.41
67 INT138719 Localization of Abcc4 1 0.75 0 0.33
68 INT80980 Regulation of Regulation of Abcb1a 1 0.45 0 0.32
69 INT80982 Regulation of Regulation of Abcb1b 1 0.60 0 0.32
70 INT143806 Positive_regulation of Negative_regulation of Abcc2 1 0.49 0 0.25
71 INT164326 Regulation of Gene_expression of Abcg2 1 0.22 0.34 0.25
72 INT143805 Positive_regulation of Negative_regulation of Abcc3 1 0.37 0 0.25
73 INT122412 Positive_regulation of Transcription of Abcc4 1 0.45 0.16 0.2
74 INT122413 Transcription of Abcc4 1 0.52 0.16 0.2
75 INT122408 Positive_regulation of Gene_expression of Abcc4 1 0.49 0.16 0.2
76 INT250673 Negative_regulation of Gene_expression of Abcb1b 2 0.42 1.66 0.19
77 INT246624 Binding of Abcc3 2 0.00 0.59 0.15
78 INT134255 Localization of Abcb1b 1 0.78 0 0.13
79 INT295162 Transcription of Abcb1b 4 0.59 1.69 0.11
80 INT285348 Negative_regulation of Negative_regulation of Abcb1a 1 0.28 0.28 0.11
81 INT341313 Regulation of EBP 1 0.45 0.1 0.1
82 INT60955 Positive_regulation of Negative_regulation of Abcb1b 1 0.30 0.23 0.1
83 INT180293 Binding of EBP 3 0.37 0.06 0.09
84 INT307936 Positive_regulation of Abcg2 3 0.57 1.92 0.08
85 INT321528 Positive_regulation of Transcription of Abcb1b 1 0.41 0.21 0.04
86 INT304992 Regulation of Binding of EBP 1 0.26 0 0.03
87 INT250679 Regulation of Positive_regulation of Abcb1b 1 0.26 0.47 0
88 INT341312 Regulation of Gene_expression of EBP 1 0.45 0 0
89 INT321523 Negative_regulation of Binding of Abcb1b 1 0.35 0 0
90 INT180292 Localization of EBP 1 0.62 0 0
91 INT168333 Negative_regulation of Transcription of Abcc2 1 0.39 0.06 0
92 INT256250 Negative_regulation of Regulation of Abcc3 1 0.20 0.68 0
93 INT187890 Negative_regulation of Abcc1 1 0.25 0.06 0
94 INT256253 Regulation of Abcc3 1 0.21 0.68 0
95 INT168334 Regulation of Transcription of Abcc2 1 0.30 0.09 0
96 INT321527 Regulation of Transcription of Abcb1b 1 0.51 0.14 0
97 INT341311 Positive_regulation of Gene_expression of EBP 1 0.50 0 0
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