GO:0006874

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Name cellular calcium ion homeostasis
Categary Process
Go Slim No
Go Link GO:0006874
Unique Molecular Interactions 2337
Total Molecular Interactions 3444
Total Single Events 38527
Pain Genes Associated 118

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular calcium ion homeostasis. They are ordered first by their pain relevance and then by number of times they were reported for cellular calcium ion homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
3 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
4 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
5 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
6 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
7 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
8 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
9 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
10 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
11 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
12 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
13 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
14 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
15 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
16 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
17 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
18 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
19 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
20 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
21 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
22 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
23 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
24 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
25 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
26 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
27 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
28 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
29 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
30 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
31 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
32 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
33 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
34 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
35 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
36 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
37 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
38 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
39 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
40 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
41 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
42 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
43 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
44 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
45 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
46 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
47 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
48 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
49 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
50 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
51 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
52 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
53 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
54 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
55 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
56 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
57 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
58 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
59 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
60 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
61 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
62 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
63 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
64 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
65 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
66 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
67 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
68 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
69 INT283050 Binding of Gad2 and Trpm8 1 0.23 2.02 1.93
70 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
71 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
72 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
73 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
74 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
75 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
76 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
77 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
78 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
79 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
80 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
81 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
82 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
83 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
84 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
85 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
86 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
87 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
88 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
89 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
90 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
91 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
92 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
93 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
94 INT134742 Binding of OPRM1 and SV2A 1 0.33 0.18 1.64
95 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
96 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
97 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
98 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
99 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
100 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
101 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
102 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
103 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
104 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
105 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
106 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
107 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
108 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
109 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
110 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
111 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
112 INT144454 Binding of DMPK and GPM6A 1 0.00 0 1.45
113 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
114 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
115 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
116 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
117 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
118 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
119 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
120 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
121 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
122 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
123 INT222213 TFAM Positive_regulation of Gene_expression of Ccr1 1 0.02 3.96 1.4
124 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
125 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
126 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
127 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
128 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
129 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
130 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
131 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
132 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
133 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
134 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
135 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
136 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
137 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
138 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
139 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
140 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
141 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
142 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
143 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
144 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
145 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
146 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
147 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27
148 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
149 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
150 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
151 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
152 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
153 INT87586 RPL7AP5 Negative_regulation of Gene_expression of Calca 1 0.00 0.05 1.21
154 INT79471 Mgat4a Regulation of Calca 1 0.06 1.09 1.21
155 INT87585 RPL7AP5 Negative_regulation of Calca 1 0.00 0.05 1.21
156 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
157 INT62019 CSF2 Regulation of ELANE 1 0.03 0.47 1.21
158 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
159 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
160 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
161 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
162 INT194403 Negative_regulation of Binding of CALCA and DCLK3 1 0.22 0 1.18
163 INT121725 Binding of Trpv1 and Pik3cb 1 0.35 0.62 1.15
164 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
165 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
166 INT348398 LPA Positive_regulation of Pik3cb 1 0.04 0.88 1.14
167 INT193288 CAP1 Positive_regulation of Pth 1 0.04 0.08 1.14
168 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
169 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
170 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
171 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
172 INT22176 Calca Regulation of Localization of Prl 4 0.69 0.39 1.11
173 INT121728 Ngf Positive_regulation of Phosphorylation of Pik3cb 1 0.45 0.69 1.11
174 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
175 INT4752 Gal Negative_regulation of Localization of Calca 1 0.41 0.06 1.11
176 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11
177 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
178 INT4753 Sst Negative_regulation of Localization of Calca 1 0.39 0.06 1.1
179 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
180 INT121730 Pik3cb Regulation of Trpv1 1 0.58 0.54 1.09
181 INT70495 CALCA Positive_regulation of CALCB 2 0.40 0 1.08
182 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
183 INT69889 Ngf Regulation of Localization of Calca 1 0.49 0.1 1.08
184 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
185 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
186 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
187 INT79372 Calca Regulation of Pnoc 1 0.34 0 1.07
188 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
189 INT181493 TRPV4 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07
190 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
191 INT329962 Binding of C5 and HEPACAM 1 0.03 2.25 1.06
192 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
193 INT121727 Pik3cb Positive_regulation of Ephb1 1 0.49 0.6 1.06
194 INT139229 Calca Negative_regulation of Cmklr1 1 0.19 1.12 1.06
195 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05
196 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05
197 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
198 INT131853 CD40 Negative_regulation of Gene_expression of CD40LG 1 0.09 1.54 1.05
199 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
200 INT312097 ELANE Regulation of ALOX5 1 0.08 1.75 1.05

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular calcium ion homeostasis. They are ordered first by their pain relevance and then by number of times they were reported in cellular calcium ion homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
4 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
5 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
6 INT2649 Regulation of Calca 433 0.62 146.05 330.95
7 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
8 INT626 Localization of CALCA 289 0.81 125.39 221.15
9 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
10 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
11 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
12 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
13 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
14 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
15 INT2541 Binding of Calca 200 0.48 67.14 134.62
16 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
17 INT5008 Localization of Calca 204 0.81 80.35 125.16
18 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
19 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
20 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
21 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
22 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
23 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
24 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
25 INT6761 Binding of CALCA 100 0.48 26.71 62.05
26 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
27 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
28 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
29 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
30 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
31 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
32 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
33 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
34 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
35 INT4891 Transcription of Calca 81 0.72 35.27 53.75
36 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
37 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
38 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
39 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
40 INT121416 Gene_expression of Trpm8 101 0.78 52.7 47.85
41 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
42 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
43 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
44 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
45 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
46 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
47 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
48 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
49 INT11246 Binding of Grin1 65 0.48 14.53 36.93
50 INT23330 Binding of Chrna7 79 0.48 10.06 35.5
51 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
52 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
53 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
54 INT109820 Gene_expression of Trpv4 121 0.78 39.69 33.11
55 INT65698 Localization of CCL2 118 0.81 77.54 32.69
56 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
57 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
58 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
59 INT117632 Gene_expression of Trpm8 99 0.78 29.41 30.9
60 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
61 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
62 INT88046 Gene_expression of Ccr2 38 0.76 33.76 28.07
63 INT22499 Regulation of Calca 42 0.62 17.32 28.02
64 INT82882 Localization of Ccl2 61 0.80 41.96 28
65 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94
66 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
67 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54
68 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
69 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26
70 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
71 INT2609 Localization of ELANE 111 0.81 50.22 26.63
72 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01
73 INT117600 Positive_regulation of Trpm8 65 0.70 31.96 24.46
74 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14
75 INT101592 Gene_expression of TRPM8 82 0.78 70.61 22.89
76 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
77 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
78 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09
79 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79
80 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7
81 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
82 INT117527 Binding of Prkca 25 0.48 6.43 21.05
83 INT49774 Binding of DRD2 48 0.48 17.42 20.73
84 INT78901 Localization of CCL5 67 0.78 40.79 20.59
85 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09
86 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81
87 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58
88 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15
89 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
90 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
91 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
92 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
93 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
94 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
95 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01
96 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
97 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86
98 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85
99 INT63928 Negative_regulation of Grin1 51 0.56 11.81 17.57
100 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
101 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
102 INT119233 Positive_regulation of Trpv4 65 0.70 20.21 17.3
103 INT16624 Localization of Grin1 38 0.79 8.46 17.15
104 INT111416 Positive_regulation of Trpm8 65 0.70 14.62 17.13
105 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
106 INT120966 Positive_regulation of Pik3cb 34 0.68 15.15 16.59
107 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
108 INT151434 Positive_regulation of Ccr2 26 0.68 18.34 16.34
109 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
110 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
111 INT79458 Localization of Prkca 30 0.81 11.13 15.78
112 INT94573 Negative_regulation of Pik3cb 42 0.50 15.83 15.4
113 INT107585 Gene_expression of CCR2 35 0.71 26.44 14.75
114 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
115 INT92513 Regulation of Grin1 26 0.59 9.12 13.94
116 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79
117 INT133156 Binding of Cd40 77 0.48 45.92 13.77
118 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
119 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
120 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
121 INT233113 Regulation of Trpm8 24 0.61 18.08 13.17
122 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15
123 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
124 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
125 INT26217 Binding of Calca 22 0.48 5.22 12.57
126 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55
127 INT107033 Gene_expression of Slc37a4 66 0.62 27.34 12.35
128 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
129 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
130 INT112103 Binding of Grin1 28 0.48 4.21 12.08
131 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
132 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
133 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7
134 INT83894 Positive_regulation of TRPM8 37 0.70 18.28 11.7
135 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
136 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
137 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
138 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83
139 INT143767 Negative_regulation of Trpm8 26 0.58 12.34 10.83
140 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8
141 INT23675 Negative_regulation of Binding of Chrna7 18 0.37 0.5 10.74
142 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
143 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
144 INT128364 Positive_regulation of Ccl3 20 0.70 23.96 10.65
145 INT9550 Gene_expression of TNNI3 113 0.78 86.79 10.56
146 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
147 INT75955 Gene_expression of Drd3 19 0.77 4.39 10.07
148 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10
149 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9
150 INT75919 Gene_expression of Slc8a1 23 0.63 16.44 9.84
151 INT83450 Positive_regulation of Localization of CCL2 28 0.70 22.14 9.83
152 INT106200 Binding of Ccl2 22 0.42 16.7 9.75
153 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51
154 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
155 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45
156 INT140224 Localization of Ccl2 32 0.72 26.91 9.39
157 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08
158 INT22083 Regulation of Pth 55 0.62 22.32 8.9
159 INT161222 Positive_regulation of Ccr2 13 0.55 13.77 8.89
160 INT121987 Phosphorylation of Grin1 11 0.80 4.73 8.88
161 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
162 INT88047 Positive_regulation of Gene_expression of Ccr2 15 0.60 10.5 8.63
163 INT82709 Negative_regulation of Slc37a4 17 0.34 3.41 8.6
164 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
165 INT8761 Negative_regulation of Binding of Calca 12 0.43 3.59 8.32
166 INT134381 Regulation of Trpm8 25 0.54 8.31 8.25
167 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24
168 INT124702 Positive_regulation of Trpv4 21 0.69 7.14 8.2
169 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08
170 INT166881 Positive_regulation of Ccr1 31 0.69 18.14 7.9
171 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
172 INT71308 Gene_expression of CCL11 33 0.76 25.66 7.83
173 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
174 INT135113 Localization of Grin1 18 0.73 3.73 7.69
175 INT18190 Regulation of DRD2 11 0.60 9.01 7.63
176 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
177 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39
178 INT25220 Positive_regulation of Binding of Calca 7 0.69 3.78 7.34
179 INT110705 Positive_regulation of Positive_regulation of Grin1 11 0.69 4.7 7.33
180 INT102548 Negative_regulation of Ccr2 14 0.59 19.84 7.22
181 INT82881 Regulation of Ccl2 19 0.57 15.29 7.19
182 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14
183 INT153271 Localization of Ccl3 7 0.81 11.29 7.14
184 INT93003 Binding of CD40 28 0.47 20.25 7.13
185 INT2605 Regulation of ELANE 39 0.61 18.22 7.11
186 INT197493 Localization of Apoe 61 0.79 27.48 7.06
187 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
188 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
189 INT112986 Positive_regulation of S100b 19 0.70 17.61 6.86
190 INT93144 Gene_expression of CCR1 18 0.75 14.69 6.84
191 INT181348 Localization of Ccl5 24 0.65 19.55 6.8
192 INT81493 Transcription of CCL2 20 0.65 13.63 6.78
193 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
194 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
195 INT64215 Gene_expression of Drd3 16 0.78 5.27 6.71
196 INT120895 Binding of CCL2 22 0.37 15.86 6.55
197 INT90461 Negative_regulation of DRD2 21 0.53 8.35 6.55
198 INT141611 Positive_regulation of Gene_expression of Ccr1 25 0.69 20.32 6.42
199 INT539 Negative_regulation of Chrna7 14 0.42 4.59 6.42
200 INT15812 Localization of CALCB 10 0.30 8.77 6.36
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