GO:0006898

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Name receptor-mediated endocytosis
Categary Process
Go Slim No
Go Link GO:0006898
Unique Molecular Interactions 410
Total Molecular Interactions 548
Total Single Events 4199
Pain Genes Associated 55

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for receptor-mediated endocytosis. They are ordered first by their pain relevance and then by number of times they were reported for receptor-mediated endocytosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14687 Binding of Penk and Ppt1 1 0.41 0 2.46
2 INT146930 CAP1 Regulation of ABCB1 1 0.29 0.3 2.19
3 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
4 INT103592 CAP1 Negative_regulation of Gene_expression of CPOX 1 0.19 1.52 1.64
5 INT351366 LPA Positive_regulation of Rab38 1 0.00 0.95 1.53
6 INT167528 Ppt1 Negative_regulation of Gene_expression of Tac4 1 0.06 0.49 1.39
7 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 1 0.26 0.49 1.38
8 INT153923 Msr1 Positive_regulation of Gene_expression of Tdo2 1 0.00 0.89 1.28
9 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 0.34 0 1.26
10 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24
11 INT69562 Positive_regulation of AP2M1 Positive_regulation of Regulation of Adrb3 1 0.01 0.19 1.24
12 INT301166 LRP2 Regulation of TRD@ 1 0.12 1.93 1.21
13 INT348398 LPA Positive_regulation of Pik3cb 1 0.04 0.88 1.14
14 INT193288 CAP1 Positive_regulation of Pth 1 0.04 0.08 1.14
15 INT348400 LPA Positive_regulation of Trib3 1 0.00 0.87 1.14
16 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08
17 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
18 INT144661 Dnm1 Negative_regulation of Binding of Hbegf 1 0.24 0 1.01
19 INT93306 Binding of TRPV1 and CAP1 2 0.18 0.07 0.97
20 INT93307 CAP1 Positive_regulation of TRPV1 1 0.15 0.07 0.96
21 INT70802 Ngf Regulation of Ppt1 1 0.21 0.39 0.93
22 INT156989 LPA Positive_regulation of Gene_expression of EFNB1 1 0.00 0.91 0.92
23 INT193291 Binding of CAP1 and Cfd 1 0.02 0.13 0.91
24 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
25 INT42865 Binding of Adrb2 and Man2a2 1 0.23 1.03 0.85
26 INT42864 Regulation of Binding of Adrb2 and Man2a2 1 0.28 1.03 0.85
27 INT338695 CAP1 Regulation of Trpv1 1 0.01 0.14 0.85
28 INT107739 Prkcg Negative_regulation of Positive_regulation of Pld2 1 0.46 0 0.79
29 INT16507 Binding of LPA and Crp 1 0.00 0.78 0.78
30 INT16494 Binding of LPA and Serpinf2 1 0.00 0.78 0.78
31 INT351364 LPA Positive_regulation of Trpv1 1 0.02 1.15 0.78
32 INT16492 Positive_regulation of Binding of LPA and Serpinf2 1 0.00 0.78 0.78
33 INT16506 Positive_regulation of Binding of LPA and Crp 1 0.00 0.78 0.78
34 INT16498 Binding of ADRA1D and LPA 1 0.10 0.78 0.78
35 INT16497 Positive_regulation of Binding of ADRA1D and LPA 1 0.10 0.78 0.78
36 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
37 INT152945 Dlg4 Regulation of Cap1 1 0.11 0.18 0.76
38 INT152946 Homer1 Regulation of Cap1 1 0.32 0.18 0.76
39 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
40 INT44503 Cubn Positive_regulation of Prl 1 0.18 0 0.74
41 INT107741 Binding of OPRM1 and Pld2 1 0.01 0 0.69
42 INT338693 Aff3 Positive_regulation of Localization of CAP1 1 0.01 0.39 0.69
43 INT351367 LPA Regulation of Trpv1 1 0.01 0.83 0.69
44 INT60051 Ptger1 Positive_regulation of STAB2 1 0.00 0.77 0.68
45 INT335054 LPL Positive_regulation of Localization of VLDLR 1 0.04 1.48 0.67
46 INT95560 Binding of Msr1 and Zfp940 1 0.00 0.24 0.66
47 INT167795 Negative_regulation of LPA Negative_regulation of Mag 1 0.01 0.84 0.64
48 INT167794 LPA Negative_regulation of Mag 1 0.01 0.77 0.63
49 INT160880 Pld2 Positive_regulation of Oprm1 1 0.07 0.08 0.63
50 INT160882 Pld2 Positive_regulation of Gene_expression of Oprm1 1 0.06 0.08 0.63
51 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
52 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
53 INT193290 CAP1 Regulation of Fth1 1 0.02 0 0.6
54 INT193265 CAP1 Regulation of STH 1 0.00 0 0.6
55 INT98725 Msr1 Positive_regulation of Gene_expression of Creb1 1 0.00 0.09 0.6
56 INT316674 Binding of CRP and SFTPD 1 0.16 2.02 0.59
57 INT193289 CAP1 Regulation of Pth 1 0.02 0 0.59
58 INT95559 Msr1 Negative_regulation of Binding of Zfp940 1 0.00 0.23 0.59
59 INT308803 Binding of Pld1 and Pld2 1 0.13 1.11 0.59
60 INT202971 Binding of BAG3 and CAP1 1 0.04 1.26 0.59
61 INT202973 Binding of CAP1 and CPP 1 0.05 1.24 0.58
62 INT202970 Binding of STC2 and CAP1 1 0.00 1.25 0.58
63 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
64 INT139429 LPA Positive_regulation of Negative_regulation of MBP 1 0.00 0.78 0.56
65 INT334013 Ccl25 Positive_regulation of Gene_expression of Lrp1 1 0.07 0.98 0.56
66 INT351365 LPA Positive_regulation of Localization of Il6 1 0.00 1.79 0.54
67 INT125086 LPA Positive_regulation of Rtn4 1 0.00 0.36 0.54
68 INT155406 Binding of Adrb2 and Ngf 1 0.05 0.39 0.53
69 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
70 INT3218 Adrb2 Positive_regulation of Localization of Ins1 1 0.10 0 0.52
71 INT292631 FOLR1 Positive_regulation of Gene_expression of IL9 1 0.00 0.46 0.51
72 INT66188 Binding of ADRB2 and CDSN 1 0.01 0 0.51
73 INT167583 ENPP2 Positive_regulation of Gene_expression of LPA 1 0.08 0.93 0.51
74 INT334901 LDLR Positive_regulation of Crp 1 0.00 1.48 0.51
75 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
76 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
77 INT243998 Binding of Prkaca and Dnm1 1 0.11 0.24 0.49
78 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
79 INT243999 Positive_regulation of Binding of Prkaca and Dnm1 1 0.14 0.24 0.49
80 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
81 INT274945 Binding of Fcgr1 and Gopc 1 0.02 0 0.49
82 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
83 INT160881 Positive_regulation of Oprm1 Positive_regulation of Positive_regulation of Pld2 1 0.05 0.08 0.48
84 INT146113 Binding of Adra2a and Lrp1 1 0.01 1.07 0.48
85 INT114593 Il1b Positive_regulation of Gene_expression of Ppt1 1 0.05 0.06 0.48
86 INT348402 LPA Positive_regulation of Gene_expression of Ptgs2 1 0.01 0.62 0.48
87 INT173293 LPA Positive_regulation of OR1S1 1 0.03 0.15 0.47
88 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
89 INT143619 Bhlhe22 Positive_regulation of Regulation of Msr1 1 0.40 0.93 0.46
90 INT35167 Adrb2 Positive_regulation of Trh 1 0.05 0 0.45
91 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
92 INT338692 CAP1 Negative_regulation of Positive_regulation of Aff3 1 0.01 0.2 0.44
93 INT63152 Ppt1 Regulation of Gene_expression of Pd 1 0.01 0 0.43
94 INT54135 Binding of F13A1 and LPA 2 0.00 0.71 0.42
95 INT54136 Negative_regulation of Binding of F13A1 and LPA 1 0.00 0.42 0.42
96 INT98726 Binding of Msr1 and Tacr2 1 0.00 0.06 0.42
97 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
98 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
99 INT114601 Il1b Positive_regulation of Transcription of Ppt1 1 0.35 0.1 0.41
100 INT92744 Binding of ADRB2 and NF2 1 0.00 0.1 0.41
101 INT75489 Binding of SGCG and Tgfbr2 1 0.23 0.83 0.41
102 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
103 INT38269 Binding of TCN1 and CUBN 1 0.00 0.28 0.4
104 INT70663 Adrb3 Regulation of Cck 1 0.14 0 0.4
105 INT23663 Cd2 Negative_regulation of Snx9 1 0.06 0 0.39
106 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
107 INT300610 Rorb Regulation of Dnm2 1 0.01 0.27 0.37
108 INT316675 Binding of CALR and SFTPD 1 0.35 0.96 0.37
109 INT300608 Arc Regulation of Dnm2 1 0.15 0.27 0.37
110 INT316672 Binding of LRP1 and SFTPD 1 0.35 0.96 0.37
111 INT316676 Binding of CRX and SFTPD 1 0.05 0.65 0.33
112 INT298472 LPA Positive_regulation of Gene_expression of CXCL16 1 0.05 0.41 0.32
113 INT263974 Binding of ADRB2 and NR4A3 1 0.01 0.5 0.32
114 INT263978 Binding of ADRB2 and TNFAIP3 1 0.01 0.5 0.32
115 INT153924 Msr1 Regulation of Adrb3 1 0.02 0.24 0.32
116 INT263979 Binding of ADRB2 and ATF3 1 0.01 0.5 0.32
117 INT207434 LPA Regulation of Gene_expression of PLA2G7 1 0.11 0.73 0.31
118 INT293203 MSR1 Regulation of Localization of IK 1 0.00 0.19 0.3
119 INT145284 Msr1 Negative_regulation of FEM1B 1 0.01 0 0.29
120 INT118545 Binding of Agtr2 and Msr1 1 0.00 0.09 0.29
121 INT326438 Binding of HFE and TAPVR1 1 0.01 0.48 0.29
122 INT145283 Msr1 Negative_regulation of Tac4 1 0.00 0 0.29
123 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
124 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
125 INT118546 Msr1 Negative_regulation of Gene_expression of CNR2 1 0.00 0.07 0.28
126 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
127 INT45196 Cubn Negative_regulation of Prl 1 0.05 0 0.27
128 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26
129 INT167582 ENPP2 Regulation of Gene_expression of LPA 1 0.05 0.61 0.26
130 INT207441 Binding of LPA and PLA2G7 1 0.10 0.56 0.26
131 INT220635 Binding of Lrp1 and Kat5 2 0.09 0.71 0.25
132 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
133 INT198926 Binding of Apbb1 and Lrp1 5 0.12 2.18 0.24
134 INT84607 Oprl1 Regulation of Adrb3 1 0.19 0.25 0.24
135 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
136 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
137 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
138 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
139 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
140 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
141 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23
142 INT34499 ADRB3 Positive_regulation of ADCY1 1 0.07 0.19 0.23
143 INT173294 LPA Positive_regulation of EGF 1 0.01 0.07 0.23
144 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
145 INT29099 Binding of ADRB2 and PPAP2A 1 0.03 0.77 0.22
146 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22
147 INT139454 Binding of IGF2R and Icam1 1 0.00 0.4 0.21
148 INT118548 Msr1 Negative_regulation of CNR2 1 0.00 0 0.2
149 INT143618 Msr1 Positive_regulation of Adrb3 1 0.16 0.85 0.2
150 INT118547 Msr1 Negative_regulation of CNR1 1 0.00 0 0.2
151 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
152 INT157083 Ghrl Regulation of Gene_expression of Ppt1 1 0.40 0 0.2
153 INT236307 SFTPD Positive_regulation of IGKV2D-38 1 0.03 0.57 0.18
154 INT197618 Binding of Esr1 and Ppt1 1 0.01 0 0.18
155 INT40819 Binding of ADRB3 and AGPAT1 1 0.24 0 0.18
156 INT349659 PYCARD Positive_regulation of ADRB2 1 0.06 0.19 0.17
157 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
158 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
159 INT122528 Apoe Regulation of Eno2 1 0.05 0.29 0.16
160 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16
161 INT297345 Apoe Negative_regulation of Csf2 1 0.17 0.66 0.16
162 INT298475 LPA Positive_regulation of Gene_expression of IL8 1 0.07 0.38 0.15
163 INT128705 Binding of Adrb2 and Ahsg 1 0.00 0.23 0.15
164 INT174892 Binding of ADRB3 and ENPP3 1 0.04 0.4 0.14
165 INT342688 Binding of Cap1 and Nav1 1 0.00 0.19 0.14
166 INT239355 Binding of Nr1h2 and Positive_regulation of Gene_expression of CETP 1 0.17 3.75 0.14
167 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14
168 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14
169 INT330486 MSR1 Negative_regulation of TAC1 1 0.01 0.23 0.13
170 INT350204 Binding of CAP1 and QPCT 1 0.06 0 0.13
171 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13
172 INT278583 Ppt1 Negative_regulation of Gene_expression of Atp6v1e1 1 0.05 0 0.13
173 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13
174 INT330485 MSR1 Negative_regulation of TACR1 1 0.01 0.23 0.13
175 INT155388 Binding of LPA and Lipg 1 0.00 1.22 0.12
176 INT270723 Negative_regulation of HMGCR Positive_regulation of LDLR 1 0.02 0.52 0.12
177 INT61916 Binding of Fcgr1 and IgG2a 1 0.47 0.93 0.12
178 INT155387 Binding of LPA and RT1-A 1 0.00 1.22 0.12
179 INT21620 Binding of Ttpa and Vldlr 1 0.22 0.27 0.12
180 INT222774 IL4 Positive_regulation of MRC1 1 0.01 0.45 0.12
181 INT222786 IL4 Positive_regulation of Positive_regulation of MRC1 1 0.01 0.45 0.12
182 INT149792 Binding of Reln and Vldlr 3 0.51 0.35 0.11
183 INT50903 Ppt1 Regulation of Tac4 1 0.18 0 0.11
184 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11
185 INT99140 LDLR Positive_regulation of Localization of VCAM1 1 0.05 0.44 0.11
186 INT292626 Gene_expression of IL9 Positive_regulation of FOLR1 1 0.00 0.25 0.11
187 INT50901 Ppt1 Regulation of Transcription of Tac4 1 0.18 0 0.11
188 INT243684 CXCL16 Negative_regulation of NDUFA2 1 0.01 0.07 0.1
189 INT153815 LPA Positive_regulation of Gene_expression of Gtf3a 1 0.00 0.16 0.1
190 INT210363 Binding of ALB and M6PR 1 0.00 1.19 0.1
191 INT208361 Positive_regulation of Binding of Apoe and Hdl1 1 0.12 1.22 0.1
192 INT243681 CXCL16 Negative_regulation of TNF 1 0.01 0.07 0.1
193 INT50533 Binding of ADRB3 and Positive_regulation of Gene_expression of CA3 1 0.11 0.61 0.1
194 INT236040 VIP Negative_regulation of SLC9A3 1 0.10 0 0.1
195 INT245927 CAP1 Negative_regulation of TRPV1 1 0.02 0.06 0.1
196 INT297346 Apoe Negative_regulation of Localization of TNF 1 0.48 0.26 0.1
197 INT273892 LPA Positive_regulation of ALB 1 0.01 0.95 0.1
198 INT308585 Binding of APOB and PLA2G7 1 0.07 0.69 0.09
199 INT294692 LPA Positive_regulation of BATF 1 0.00 0 0.09
200 INT205204 LPA Positive_regulation of Positive_regulation of Pik3c3 1 0.02 0.22 0.09

Single Events

The table below shows the top 100 pain related interactions that have been reported for receptor-mediated endocytosis. They are ordered first by their pain relevance and then by number of times they were reported in receptor-mediated endocytosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9650 Gene_expression of LPA 141 0.75 104.57 29
2 INT14575 Positive_regulation of Ppt1 60 0.70 9.97 27.4
3 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
4 INT4890 Gene_expression of Ppt1 51 0.77 8.93 21.83
5 INT4894 Transcription of Ppt1 34 0.67 5.93 21.06
6 INT663 Negative_regulation of Adrb3 55 0.59 15.95 14.68
7 INT8794 Negative_regulation of Ppt1 35 0.57 6.44 14.52
8 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89
9 INT110 Regulation of Adrb3 33 0.60 8.09 13.84
10 INT91357 Regulation of Dnm2 5 0.61 0 11.06
11 INT1087 Negative_regulation of Msr1 32 0.57 8.35 10.72
12 INT8188 Positive_regulation of Adrb3 27 0.68 7.32 10.44
13 INT8249 Positive_regulation of Cubn 15 0.66 4.05 9.35
14 INT106595 Negative_regulation of Dnm2 10 0.58 0.15 9.29
15 INT13893 Negative_regulation of Cubn 9 0.36 1.78 9.24
16 INT93309 Positive_regulation of CAP1 17 0.43 11.4 9.13
17 INT29411 Positive_regulation of ADRB2 13 0.65 5.42 8.78
18 INT93310 Gene_expression of CAP1 14 0.58 3.07 8.55
19 INT24651 Positive_regulation of Transcription of Ppt1 12 0.47 2.88 8.42
20 INT153814 Localization of LPA 19 0.65 18.25 7.68
21 INT298 Negative_regulation of ADRB3 23 0.59 6.82 7.56
22 INT7883 Binding of ADRB2 18 0.47 5.49 7.37
23 INT5774 Regulation of Ppt1 22 0.60 4.97 7.1
24 INT197493 Localization of Apoe 61 0.79 27.48 7.06
25 INT106599 Positive_regulation of Dnm2 8 0.69 0.28 7.01
26 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
27 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84
28 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
29 INT107737 Positive_regulation of Pld2 11 0.67 0.33 6.45
30 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21
31 INT63042 Binding of Apoe 59 0.48 31.23 5.88
32 INT4888 Positive_regulation of Gene_expression of Ppt1 9 0.54 2.78 5.83
33 INT4282 Regulation of Msr1 11 0.45 2.51 5.75
34 INT1243 Regulation of ADRB2 16 0.54 1.84 5.66
35 INT102836 Binding of LRP2 12 0.38 11.27 5.58
36 INT55353 Negative_regulation of Positive_regulation of Ppt1 9 0.57 0.31 5.37
37 INT13885 Positive_regulation of Adrb2 9 0.49 1.11 5.12
38 INT11030 Binding of LPA 70 0.48 40.35 4.81
39 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
40 INT236335 Gene_expression of SFTPD 26 0.75 15.92 4.59
41 INT88909 Positive_regulation of Gene_expression of Dnm1 6 0.70 3.43 4.59
42 INT46350 Gene_expression of Msr1 32 0.65 29.39 4.55
43 INT106596 Transcription of Dnm2 4 0.69 0 4.5
44 INT24930 Binding of Adrb2 6 0.26 4.18 4.44
45 INT4104 Gene_expression of ADRB3 19 0.78 2.68 4.12
46 INT173910 Gene_expression of LRP2 24 0.75 19.99 4.09
47 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
48 INT484 Negative_regulation of ADRB2 13 0.59 2.85 3.94
49 INT109 Binding of ADRB3 17 0.47 3.02 3.84
50 INT112928 Localization of Dnm2 3 0.74 0 3.81
51 INT75485 Gene_expression of Tgfbr2 10 0.57 10.98 3.76
52 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
53 INT18822 Regulation of Cubn 4 0.27 0.17 3.74
54 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
55 INT88906 Gene_expression of Dnm1 5 0.78 10.48 3.7
56 INT6882 Binding of Adrb2 5 0.47 1.97 3.55
57 INT32905 Gene_expression of Mrc1 18 0.58 11.07 3.54
58 INT193281 Binding of CAP1 7 0.07 4.57 3.53
59 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
60 INT10106 Positive_regulation of Msr1 16 0.50 5.86 3.52
61 INT55352 Regulation of Gene_expression of Ppt1 9 0.44 0.4 3.51
62 INT57728 Regulation of LDLR 25 0.41 13.18 3.46
63 INT16626 Positive_regulation of Adrb2 10 0.30 2.41 3.4
64 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32
65 INT14857 Negative_regulation of Gene_expression of Ppt1 7 0.42 1.16 3.3
66 INT43985 Regulation of LPA 29 0.62 20.79 3.29
67 INT72141 Binding of Apoe 11 0.37 10.91 3.27
68 INT192450 Gene_expression of CLTC 26 0.55 18.82 3.26
69 INT162372 Positive_regulation of SFTPD 15 0.67 11.8 3.21
70 INT97710 Localization of Apoe 1 0.79 7.18 3.2
71 INT137961 Localization of Ppt1 1 0.64 2.89 3.09
72 INT27100 Binding of Adrb3 10 0.47 3.44 3.07
73 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04
74 INT41474 Gene_expression of ADRB2 10 0.75 1.56 2.94
75 INT123910 Gene_expression of CXCL16 5 0.49 3.81 2.82
76 INT33480 Gene_expression of Adrb2 4 0.66 1.96 2.77
77 INT121463 Regulation of Localization of Dnm2 2 0.45 0 2.72
78 INT49759 Negative_regulation of CETP 43 0.58 52 2.68
79 INT50080 Binding of APOE 38 0.45 29.61 2.67
80 INT49473 Gene_expression of MSR1 14 0.75 7.28 2.64
81 INT146931 Regulation of CAP1 1 0.44 0.22 2.58
82 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
83 INT514 Gene_expression of Adrb2 3 0.53 0.23 2.46
84 INT105694 Binding of SFTPD 11 0.46 8.47 2.45
85 INT18202 Localization of Adrb3 7 0.80 2.76 2.44
86 INT65732 Binding of Msr1 9 0.47 7.28 2.42
87 INT75756 Phosphorylation of LPA 5 0.68 0.67 2.35
88 INT9764 Gene_expression of Adrb3 10 0.62 4.14 2.33
89 INT74237 Positive_regulation of Ppt1 3 0.49 2.92 2.32
90 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
91 INT190028 Positive_regulation of Mrc1 10 0.22 2.94 2.26
92 INT3531 Regulation of Adrb2 7 0.44 1.48 2.25
93 INT30372 Regulation of ADRB3 8 0.60 0.57 2.24
94 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
95 INT195191 Gene_expression of Cubn 2 0.06 0 2.17
96 INT34500 Positive_regulation of ADRB3 12 0.58 2.59 2.16
97 INT70725 Negative_regulation of Binding of ADRB2 3 0.57 0.4 2.14
98 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
99 INT107987 Gene_expression of MRC1 27 0.75 36.94 1.99
100 INT262364 Positive_regulation of LRP2 6 0.39 4.44 1.97
101 INT245945 Localization of CAP1 4 0.69 1.63 1.95
102 INT198885 Gene_expression of Lrp1 33 0.57 10.2 1.91
103 INT41633 Positive_regulation of Positive_regulation of Cubn 2 0.48 0.1 1.89
104 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
105 INT245577 Localization of SFTPD 7 0.63 10.43 1.84
106 INT40832 Localization of ADRB2 5 0.73 2.21 1.81
107 INT14862 Negative_regulation of Transcription of Ppt1 3 0.42 0 1.8
108 INT9648 Positive_regulation of Gene_expression of LPA 15 0.59 11.31 1.72
109 INT144292 Binding of Ppt1 9 0.37 2.02 1.71
110 INT58456 Gene_expression of HFE 10 0.58 7.68 1.65
111 INT111886 Gene_expression of Dnm2 3 0.69 0.91 1.65
112 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
113 INT1088 Negative_regulation of Negative_regulation of Msr1 5 0.40 0.65 1.61
114 INT212048 Negative_regulation of SFTPD 3 0.42 5.45 1.61
115 INT9466 Binding of APOB 27 0.41 19.36 1.56
116 INT193284 Positive_regulation of Gene_expression of CAP1 1 0.07 0.05 1.55
117 INT43482 Regulation of Binding of ADRB3 4 0.60 1.06 1.54
118 INT110749 Gene_expression of Ppt1 9 0.34 0.51 1.49
119 INT107735 Positive_regulation of Positive_regulation of Pld2 3 0.48 0 1.47
120 INT340324 Regulation of Ppt1 1 0.13 1.17 1.47
121 INT114490 Gene_expression of PDLIM7 17 0.78 11.35 1.42
122 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
123 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39
124 INT5466 Positive_regulation of Negative_regulation of ADRB3 2 0.44 0.17 1.39
125 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
126 INT4889 Regulation of Transcription of Ppt1 3 0.35 0.89 1.34
127 INT53316 Localization of Ppt1 5 0.65 1.59 1.32
128 INT106598 Regulation of Regulation of Dnm2 1 0.44 0 1.31
129 INT63532 Positive_regulation of Positive_regulation of Ppt1 2 0.67 0 1.29
130 INT68471 Negative_regulation of Positive_regulation of Adrb3 1 0.42 0.14 1.29
131 INT72147 Phosphorylation of Cttn 3 0.28 0.64 1.27
132 INT20238 Regulation of APOB 9 0.61 11.52 1.26
133 INT134026 Positive_regulation of Dnm1 2 0.49 0.38 1.25
134 INT107732 Gene_expression of Pld2 1 0.75 0 1.25
135 INT210399 Gene_expression of IGF2R 22 0.65 17.1 1.23
136 INT126812 Gene_expression of Cttn 9 0.57 0.81 1.23
137 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
138 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
139 INT121461 Binding of Dnm2 1 0.24 0 1.23
140 INT257952 Positive_regulation of CUBN 1 0.07 0.61 1.22
141 INT55351 Positive_regulation of Negative_regulation of Ppt1 3 0.45 0 1.19
142 INT44498 Localization of Cubn 2 0.34 0.38 1.19
143 INT23199 Binding of LDLR 22 0.47 17.08 1.16
144 INT176317 Transcription of CAP1 3 0.16 1.8 1.15
145 INT173916 Regulation of LRP2 6 0.44 7.96 1.14
146 INT82703 Transcription of LDLR 6 0.64 0.4 1.13
147 INT112929 Negative_regulation of Localization of Dnm2 1 0.29 0 1.13
148 INT41333 Negative_regulation of Positive_regulation of Cubn 2 0.15 0.47 1.12
149 INT41475 Positive_regulation of Localization of ADRB2 2 0.49 0.18 1.12
150 INT75698 Negative_regulation of Negative_regulation of Ppt1 1 0.42 1.01 1.11
151 INT198879 Localization of Vldlr 6 0.39 0.58 1.1
152 INT75699 Negative_regulation of Ppt1 2 0.58 1.07 1.08
153 INT88907 Localization of Dnm1 2 0.81 1 1.08
154 INT88908 Positive_regulation of Localization of Dnm1 1 0.45 0.33 1.08
155 INT247970 Regulation of CLTC 8 0.28 5.37 1.06
156 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
157 INT58457 Positive_regulation of HFE 3 0.28 2.75 1.04
158 INT206140 Negative_regulation of Gene_expression of LPA 5 0.43 3.71 1.03
159 INT121462 Regulation of Transcription of Dnm2 1 0.20 0 1.03
160 INT98860 Gene_expression of Dnm1 1 0.75 0 1.03
161 INT49796 Positive_regulation of Binding of Adrb2 1 0.00 0 1.02
162 INT52186 Positive_regulation of Positive_regulation of ADRB2 1 0.14 0 1.02
163 INT49795 Negative_regulation of Binding of Adrb2 1 0.00 0 1.02
164 INT198904 Localization of Lrp1 11 0.62 3.25 1.01
165 INT52113 Gene_expression of CETP 25 0.69 25.71 0.99
166 INT82707 Positive_regulation of Transcription of LDLR 1 0.62 0.34 0.98
167 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
168 INT138548 Negative_regulation of Gene_expression of Adrb2 1 0.41 0.85 0.96
169 INT82702 Positive_regulation of Positive_regulation of LDLR 4 0.45 1.08 0.95
170 INT111885 Negative_regulation of Transcription of Dnm2 1 0.47 0 0.93
171 INT125580 Positive_regulation of Regulation of Dnm2 1 0.69 0 0.92
172 INT198872 Binding of Lrp1 9 0.36 2.73 0.89
173 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88
174 INT139449 Negative_regulation of IGF2R 5 0.15 2.58 0.87
175 INT125581 Negative_regulation of Gene_expression of Dnm2 1 0.37 0 0.87
176 INT14976 Negative_regulation of Adrb2 3 0.24 0.75 0.86
177 INT55350 Regulation of Negative_regulation of Ppt1 2 0.60 0 0.86
178 INT70726 Positive_regulation of Negative_regulation of ADRB2 1 0.49 0.2 0.86
179 INT236328 Regulation of SFTPD 6 0.38 3.04 0.85
180 INT42863 Regulation of Adrb2 1 0.11 1.02 0.85
181 INT42862 Regulation of Binding of Adrb2 1 0.15 1.03 0.85
182 INT95561 Negative_regulation of Vldlr 9 0.53 2.59 0.84
183 INT191528 Positive_regulation of Localization of LPA 1 0.05 3.59 0.83
184 INT193286 Regulation of Gene_expression of CAP1 1 0.06 0 0.83
185 INT125582 Regulation of Positive_regulation of Dnm2 1 0.27 0 0.83
186 INT292650 Positive_regulation of FOLR1 1 0.01 0.95 0.82
187 INT98852 Negative_regulation of Gene_expression of Dnm1 1 0.41 0 0.81
188 INT275575 Gene_expression of FOLR1 12 0.66 2.81 0.8
189 INT86910 Negative_regulation of MRC1 6 0.20 6.52 0.8
190 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8
191 INT1852 Localization of ADRB3 3 0.75 1.02 0.79
192 INT16482 Regulation of Positive_regulation of LPA 1 0.08 0.79 0.79
193 INT173914 Regulation of Gene_expression of LRP2 3 0.60 6.49 0.78
194 INT33481 Positive_regulation of Gene_expression of Adrb2 2 0.48 0.38 0.78
195 INT98859 Negative_regulation of Binding of Dnm1 1 0.41 0 0.78
196 INT98844 Binding of Dnm1 1 0.36 0 0.78
197 INT72149 Regulation of Cttn 3 0.31 0.95 0.76
198 INT44500 Regulation of Localization of Cubn 1 0.20 0 0.75
199 INT10105 Regulation of Positive_regulation of Msr1 1 0.45 0 0.75
200 INT107736 Positive_regulation of Gene_expression of Pld2 1 0.67 0 0.74
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