GO:0006911

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Name phagocytosis, engulfment
Categary Process
Go Slim No
Go Link GO:0006911
Unique Molecular Interactions 122
Total Molecular Interactions 144
Total Single Events 894
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phagocytosis, engulfment. They are ordered first by their pain relevance and then by number of times they were reported for phagocytosis, engulfment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT289173 PYCARD Regulation of MFGE8 1 0.05 0 0.96
2 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
3 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
4 INT119105 Binding of FCGR1A and TNF 1 0.03 1.16 0.67
5 INT119106 Negative_regulation of Binding of FCGR1A and TNF 1 0.03 1.16 0.67
6 INT31942 Binding of FCGR1A and Oprd1 1 0.00 0 0.62
7 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
8 INT119030 Binding of POMC and Ighg1 1 0.06 0 0.52
9 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
10 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
11 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
12 INT274945 Binding of Fcgr1 and Gopc 1 0.02 0 0.49
13 INT346325 Sirpa Regulation of Obfc1 1 0.00 0.41 0.48
14 INT203150 Binding of Ighg2b and IgG2a 1 0.11 1.35 0.47
15 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
16 INT68252 Penk Positive_regulation of Transcription of Ighg1 1 0.44 0 0.44
17 INT157656 Binding of RUNX1 and FCGR1A 1 0.02 0.07 0.4
18 INT157657 Binding of CTLA4 and FCGR1A 1 0.01 0.07 0.4
19 INT157658 Binding of FCGR1A and SGCG 1 0.07 0.07 0.4
20 INT173977 Binding of TNF and Ighg1 1 0.03 0.28 0.39
21 INT112020 Binding of Ighg1 and IgG2a 2 0.25 0.36 0.36
22 INT112024 Binding of Hand1 and Ighg1 2 0.30 0.84 0.33
23 INT112019 Binding of Ifng and Ighg1 1 0.10 0.3 0.33
24 INT241139 Ighg1 Positive_regulation of Hand2 1 0.06 0.65 0.32
25 INT241138 Ighg1 Positive_regulation of Hand1 1 0.06 0.64 0.32
26 INT289178 Regulation of PYCARD Regulation of MFGE8 1 0.05 0 0.32
27 INT284047 Vtcn1 Negative_regulation of Gene_expression of Ighg2b 1 0.05 0.68 0.3
28 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3
29 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3
30 INT351143 Binding of Cd3e and Ighg2a 1 0.00 1.56 0.25
31 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
32 INT289174 PYCARD Positive_regulation of MFGE8 1 0.05 0 0.21
33 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
34 INT289176 PYCARD Regulation of Localization of MFGE8 1 0.05 0 0.18
35 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
36 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17
37 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17
38 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
39 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17
40 INT207350 TBXA2R Regulation of Gene_expression of ABCA1 1 0.10 0 0.17
41 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16
42 INT207338 Negative_regulation of CPOX Negative_regulation of ABCA1 1 0.11 0 0.16
43 INT276958 Binding of Tlr2 and Clec7a 1 0.09 0.58 0.15
44 INT252352 Binding of THBS1 and Sirpa 1 0.00 0.26 0.15
45 INT335459 ABCA1 Positive_regulation of ITPR3 1 0.00 0 0.15
46 INT279031 Binding of Sirpa and Cd47 1 0.09 0.77 0.15
47 INT51355 Binding of FCGR1A and IGHE 1 0.36 0.1 0.15
48 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14
49 INT207360 PTGDS Negative_regulation of Negative_regulation of ABCA1 1 0.25 0 0.14
50 INT207337 PTGER2 Negative_regulation of Negative_regulation of ABCA1 1 0.04 0 0.14
51 INT207353 ZNF398 Regulation of ABCA1 1 0.00 0 0.14
52 INT107647 Ighg1 Negative_regulation of Arigg4 1 0.01 0.5 0.14
53 INT107645 Arigg4 Negative_regulation of Ighg1 1 0.01 0.5 0.14
54 INT311737 Plat Regulation of Positive_regulation of Fcgr2b 1 0.31 0.71 0.13
55 INT351144 Binding of Ighg2b and Ighg2a 1 0.00 0.78 0.12
56 INT61916 Binding of Fcgr1 and IgG2a 1 0.47 0.93 0.12
57 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12
58 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
59 INT293236 IDO1 Regulation of ABCA1 1 0.00 0 0.11
60 INT311735 Binding of Plat and Fcgr2b 1 0.29 0.65 0.1
61 INT42224 ABCA1 Positive_regulation of CYBB 1 0.01 0 0.09
62 INT185073 Bpifa2 Positive_regulation of Ighg1 1 0.27 0.93 0.09
63 INT42225 Binding of ABCA1 and DECR1 1 0.02 0 0.08
64 INT289258 Binding of ABCA1 and Il6ra 1 0.00 0.33 0.07
65 INT355828 Binding of MFGE8 and SEA 1 0.01 0.07 0.07
66 INT351142 Binding of Cd3e and Ighg2b 1 0.03 0.6 0.07
67 INT345292 Binding of Lcn2 and Havcr1 1 0.00 1.17 0.07
68 INT74033 Binding of IGHG3 and Ighg1 2 0.08 0.87 0.06
69 INT61915 Binding of Fcgr1 and Slc3a2 1 0.02 0.43 0.06
70 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06
71 INT293233 IDO1 Positive_regulation of ABCA1 1 0.01 0 0.06
72 INT339583 Binding of ABCA1 and RPE 1 0.03 1.38 0.05
73 INT339587 Positive_regulation of Binding of ABCA1 and RPE 1 0.04 1.38 0.05
74 INT188432 Negative_regulation of Binding of ABCA1 and IL6 1 0.02 0.47 0.05
75 INT320353 IFNA1 Positive_regulation of Gene_expression of Ighg2b 1 0.02 0 0.05
76 INT223520 Erv4 Regulation of Regulation of Fcgr1 1 0.06 0.93 0.05
77 INT188431 Binding of ABCA1 and IL6 1 0.02 0.47 0.05
78 INT235969 Binding of Ighg1 and Nqo1 1 0.01 2.63 0.04
79 INT230136 OSBPL8 Regulation of Binding of ABCA1 1 0.07 0.17 0.03
80 INT207343 Negative_regulation of CPOX Negative_regulation of Gene_expression of ABCA1 1 0.09 0 0.03
81 INT165191 Fabp1 Positive_regulation of Havcr1 1 0.03 0.21 0
82 INT284392 Binding of ABCA1 and Vegfa 1 0.00 0.71 0
83 INT229927 CD59 Negative_regulation of Binding of ABCA1 1 0.01 0 0
84 INT320351 Pnp Regulation of Ighg2b 1 0.02 0.31 0
85 INT215128 Ighm Regulation of Ighg1 1 0.12 0.27 0
86 INT165197 Positive_regulation of Binding of IL18 and Havcr1 1 0.00 0.28 0
87 INT165195 Binding of IL18 and Havcr1 1 0.00 0.28 0
88 INT229923 Binding of ABCA1 and C9 1 0.00 0.74 0
89 INT215131 Ighg1 Regulation of Ighg2b 1 0.16 0.27 0
90 INT215127 Ighg1 Regulation of Ighm 1 0.12 0.27 0
91 INT284372 Binding of ABCA1 and AMT 1 0.00 0 0
92 INT84739 Binding of Ighg1 and Cea 1 0.31 0.43 0
93 INT320352 Pnp Positive_regulation of Ighg2b 1 0.03 0.08 0
94 INT239341 Binding of Abca1 and Hdl1 1 0.04 4.78 0
95 INT297056 Binding of ABCA1 and Oas1b 1 0.00 0.13 0
96 INT117795 ABCA1 Regulation of GHRL 1 0.00 0 0
97 INT284393 Positive_regulation of Binding of ABCA1 and Vegfa 1 0.00 0.36 0
98 INT326085 Prkaca Regulation of Phosphorylation of ABCA1 1 0.02 0.44 0
99 INT229981 Binding of ABCA1 and Cdca3 1 0.00 0.74 0
100 INT144760 Binding of ABCA1 and Insr 1 0.00 0 0
101 INT339580 TIMP3 Positive_regulation of ABCA1 1 0.16 0.73 0
102 INT284829 Binding of FCGR3A and Ighg1 1 0.00 0.13 0
103 INT289295 Binding of CD59 and Fcgr3 1 0.01 1.06 0
104 INT326060 Binding of ABCA1 and APOA1 1 0.39 1.5 0
105 INT307283 Binding of ABCA1 and PMP2 1 0.00 0 0
106 INT326084 Prkaca Positive_regulation of Phosphorylation of ABCA1 1 0.06 0.44 0
107 INT217396 Binding of Abca1 and App 1 0.26 0.83 0
108 INT344712 Nr1h3 Regulation of Abca1 1 0.03 1.68 0
109 INT215129 Ighg1 Regulation of Gene_expression of Ctsd 1 0.35 0.26 0
110 INT194243 Binding of SFSWAP and Ighg1 1 0.01 0.46 0
111 INT348534 ELMO1 Positive_regulation of RAC1 1 0.02 0.7 0
112 INT225891 DOCK1 Positive_regulation of RAC1 1 0.01 0 0
113 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0
114 INT225893 Binding of CRKL and DOCK1 1 0.01 0 0
115 INT215132 Ighm Regulation of Ighg2b 1 0.11 0.27 0
116 INT215130 Ighg1 Regulation of Negative_regulation of Ctsd 1 0.21 0.27 0
117 INT225899 Binding of DOCK1 and RAC1 1 0.01 0 0
118 INT225907 Binding of CRK and DOCK1 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for phagocytosis, engulfment. They are ordered first by their pain relevance and then by number of times they were reported in phagocytosis, engulfment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92
2 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
3 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
4 INT113254 Positive_regulation of MFGE8 13 0.09 2.52 5.56
5 INT14357 Positive_regulation of FCGR1A 10 0.44 7.14 5.4
6 INT68244 Positive_regulation of Ighg1 60 0.61 48.86 5.01
7 INT2848 Localization of ABCA1 23 0.70 10.64 4.73
8 INT289208 Gene_expression of MFGE8 13 0.08 0.25 3.7
9 INT9223 Localization of Ighg1 22 0.78 11.03 3.67
10 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39
11 INT28130 Positive_regulation of ABCA1 18 0.61 7.08 3.22
12 INT31940 Binding of FCGR1A 6 0.35 2.16 3.1
13 INT289211 Localization of MFGE8 11 0.09 0.19 2.69
14 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
15 INT49930 Binding of Ighg1 21 0.37 13.27 2.43
16 INT173504 Positive_regulation of Gene_expression of Ighg1 16 0.47 7.2 2.36
17 INT289207 Binding of MFGE8 1 0.06 0 1.92
18 INT184006 Gene_expression of Ighg2b 21 0.71 7.97 1.86
19 INT207370 Negative_regulation of Gene_expression of ABCA1 1 0.54 2.75 1.78
20 INT68250 Regulation of Gene_expression of Ighg1 7 0.40 2.99 1.56
21 INT107641 Negative_regulation of Ighg1 19 0.39 11.44 1.54
22 INT131457 Gene_expression of FCGR1A 11 0.75 4.88 1.45
23 INT112013 Negative_regulation of Gene_expression of Ighg1 7 0.38 3.57 1.42
24 INT68248 Transcription of Ighg1 3 0.61 3.02 1.25
25 INT289209 Regulation of MFGE8 3 0.05 0.2 1.13
26 INT139679 Positive_regulation of Ighg2b 11 0.55 10.57 1.1
27 INT180382 Gene_expression of Fcgr3 9 0.34 7.94 1.1
28 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
29 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04
30 INT171113 Binding of Ighg2b 3 0.47 2.85 0.96
31 INT113256 Negative_regulation of Positive_regulation of MFGE8 2 0.08 0.25 0.95
32 INT138683 Regulation of Ighg1 15 0.30 7.95 0.94
33 INT289205 Negative_regulation of MFGE8 4 0.05 0 0.94
34 INT190089 Binding of Abca1 5 0.36 2.21 0.83
35 INT181711 Positive_regulation of Gene_expression of Fcgr3 2 0.08 1.67 0.74
36 INT164627 Positive_regulation of Gene_expression of ABCA1 9 0.61 3.95 0.67
37 INT184373 Gene_expression of Sirpa 2 0.23 1.8 0.6
38 INT138836 Regulation of FCGR1A 1 0.37 1.02 0.58
39 INT277710 Regulation of Localization of ABCA1 1 0.04 1.73 0.56
40 INT184049 Positive_regulation of Gene_expression of Ighg2b 2 0.40 1.54 0.53
41 INT203131 Regulation of Binding of Ighg2b 1 0.31 1.36 0.49
42 INT279020 Gene_expression of Sirpa 1 0.18 1.45 0.47
43 INT167468 Regulation of Gene_expression of ABCA1 5 0.52 0.08 0.43
44 INT68237 Positive_regulation of Transcription of Ighg1 1 0.44 0 0.43
45 INT168250 Gene_expression of Havcr1 4 0.56 2.81 0.42
46 INT184342 Positive_regulation of Binding of Sirpa 1 0.04 1.56 0.42
47 INT61912 Gene_expression of Fcgr1 3 0.69 1.13 0.41
48 INT184369 Negative_regulation of Sirpa 1 0.03 1.52 0.41
49 INT184372 Binding of Sirpa 1 0.03 1.52 0.41
50 INT209180 Transcription of ABCA1 4 0.47 1.09 0.39
51 INT345322 Regulation of Transcription of ABCA1 1 0.01 0 0.39
52 INT289192 Negative_regulation of Gene_expression of MFGE8 1 0.05 0 0.39
53 INT167122 Protein_catabolism of ABCA1 3 0.02 0.27 0.37
54 INT39350 Positive_regulation of Ighg2a 2 0.35 2.39 0.37
55 INT220962 Positive_regulation of Localization of Ighg1 2 0.46 2.58 0.37
56 INT27205 Binding of Fcgr1 1 0.02 0 0.37
57 INT274912 Regulation of Gene_expression of Fcgr1 1 0.05 0 0.35
58 INT145457 Positive_regulation of Clec7a 2 0.04 0.17 0.34
59 INT289212 Regulation of Localization of MFGE8 1 0.05 0 0.34
60 INT289206 Positive_regulation of Localization of MFGE8 1 0.06 0 0.34
61 INT224714 Localization of Ighg2b 4 0.73 0.48 0.33
62 INT289210 Negative_regulation of Localization of MFGE8 1 0.05 0 0.33
63 INT70133 Positive_regulation of Positive_regulation of FCGR1A 1 0.44 0.73 0.33
64 INT239295 Positive_regulation of Abca1 3 0.30 2.18 0.32
65 INT323835 Negative_regulation of Binding of Ighg1 1 0.23 0.67 0.31
66 INT323834 Regulation of Binding of Ighg1 1 0.24 0.69 0.31
67 INT55154 Positive_regulation of Havcr1 3 0.07 1.22 0.3
68 INT279017 Positive_regulation of Sirpa 1 0.16 0.69 0.29
69 INT215118 Negative_regulation of Ighg2b 2 0.30 0.93 0.28
70 INT239279 Regulation of Gene_expression of Abca1 2 0.44 2.42 0.26
71 INT344685 Positive_regulation of Binding of Abca1 1 0.12 0.76 0.26
72 INT284385 Positive_regulation of Localization of ABCA1 2 0.02 0.22 0.25
73 INT289199 Regulation of Binding of MFGE8 1 0.05 0 0.24
74 INT289203 Regulation of Gene_expression of MFGE8 1 0.05 0 0.21
75 INT239287 Transcription of Abca1 1 0.32 1.87 0.21
76 INT300227 Positive_regulation of Binding of ABCA1 1 0.41 1.85 0.19
77 INT277709 Regulation of Binding of ABCA1 1 0.04 0.52 0.19
78 INT239308 Positive_regulation of Transcription of Abca1 1 0.28 0.67 0.18
79 INT339625 Binding of Clec7a 1 0.03 0.14 0.17
80 INT217387 Regulation of Abca1 3 0.27 2.01 0.15
81 INT238679 Negative_regulation of Localization of Ighg1 2 0.39 0.61 0.15
82 INT317803 Negative_regulation of Ighg2a 1 0.02 0.71 0.15
83 INT189508 Positive_regulation of Sirpa 2 0.11 1.04 0.14
84 INT317802 Regulation of Ighg2a 1 0.01 0.49 0.14
85 INT317804 Regulation of Gene_expression of Ighg2a 1 0.01 0.5 0.14
86 INT291486 Regulation of Havcr1 1 0.01 0.78 0.13
87 INT317801 Gene_expression of Ighg2a 1 0.03 0.49 0.13
88 INT311718 Positive_regulation of Fcgr2b 1 0.30 0.68 0.12
89 INT79184 Positive_regulation of Fcgr3 2 0.13 0.52 0.1
90 INT279024 Binding of Sirpa 1 0.09 0.35 0.1
91 INT318637 Binding of Havcr1 1 0.01 0.91 0.1
92 INT303410 Regulation of Ighg2b 2 0.25 1.22 0.09
93 INT303412 Positive_regulation of Regulation of Ighg2b 2 0.43 1.23 0.09
94 INT42227 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0 0.09
95 INT42226 Positive_regulation of Positive_regulation of ABCA1 1 0.02 0 0.09
96 INT107642 Positive_regulation of Positive_regulation of Ighg1 2 0.30 1.35 0.08
97 INT334229 Regulation of Sirpa 1 0.07 0.63 0.08
98 INT180387 Regulation of Gene_expression of FCGR1A 1 0.05 0.88 0.08
99 INT334220 Positive_regulation of Regulation of Sirpa 1 0.08 0.63 0.08
100 INT262061 Negative_regulation of Gene_expression of Abca1 1 0.19 0.68 0.08
101 INT276937 Localization of Clec7a 1 0.14 0.23 0.07
102 INT61911 Negative_regulation of Gene_expression of Fcgr1 1 0.38 0.39 0.07
103 INT223510 Regulation of Fcgr1 1 0.11 0.92 0.05
104 INT239296 Negative_regulation of Abca1 3 0.26 3.83 0.04
105 INT192405 Positive_regulation of Regulation of Ighg1 1 0.26 0 0.04
106 INT253595 Localization of Abca1 2 0.37 0.35 0.03
107 INT211289 Binding of Fcgr3 1 0.19 0.28 0.03
108 INT320337 Regulation of Gene_expression of Ighg2b 1 0.25 0 0.03
109 INT320331 Negative_regulation of Gene_expression of Ighg2b 1 0.39 0.05 0.03
110 INT211301 Negative_regulation of Binding of Fcgr3 1 0.22 0.34 0.03
111 INT277787 Protein_catabolism of Ighg1 1 0.35 0.11 0.03
112 INT129802 Gene_expression of Clec7a 5 0.13 0.51 0
113 INT326077 Positive_regulation of Transcription of ABCA1 1 0.41 0.22 0
114 INT326076 Phosphorylation of ABCA1 1 0.73 0.66 0
115 INT344200 Localization of Fcgr1 1 0.28 0.4 0
116 INT225858 Binding of DOCK1 1 0.05 0 0
117 INT276944 Regulation of Clec7a 1 0.05 0 0
118 INT348501 Positive_regulation of ELMO1 1 0.16 1.36 0
119 INT129801 Positive_regulation of Gene_expression of Clec7a 1 0.04 0.38 0
120 INT264196 Positive_regulation of Gene_expression of FCGR1A 1 0.22 0.37 0
121 INT326083 Positive_regulation of Phosphorylation of ABCA1 1 0.61 0.66 0
122 INT344196 Positive_regulation of Localization of Fcgr1 1 0.19 0.4 0
123 INT170735 Positive_regulation of Gene_expression of Fcgr1 1 0.15 0.74 0
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