GO:0006914

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Name autophagy
Categary Process
Go Slim No
Go Link GO:0006914
Unique Molecular Interactions 553
Total Molecular Interactions 752
Total Single Events 5597
Pain Genes Associated 37

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for autophagy. They are ordered first by their pain relevance and then by number of times they were reported for autophagy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
2 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
3 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25
4 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
5 INT211744 Binding of Gopc and Mors1 1 0.10 0.2 1.48
6 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
7 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
8 INT229496 Binding of Ndel1 and Gopc 1 0.08 2.05 1.36
9 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
10 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
11 INT121725 Binding of Trpv1 and Pik3cb 1 0.35 0.62 1.15
12 INT348398 LPA Positive_regulation of Pik3cb 1 0.04 0.88 1.14
13 INT121728 Ngf Positive_regulation of Phosphorylation of Pik3cb 1 0.45 0.69 1.11
14 INT121730 Pik3cb Regulation of Trpv1 1 0.58 0.54 1.09
15 INT121727 Pik3cb Positive_regulation of Ephb1 1 0.49 0.6 1.06
16 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
17 INT264924 Binding of Pag1 and Gopc 1 0.06 0.19 0.94
18 INT354522 Binding of HBG2 and Wipi1 1 0.00 2.64 0.87
19 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
20 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82
21 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82
22 INT296786 Gopc Regulation of Positive_regulation of Il1 1 0.02 1.37 0.77
23 INT296798 Gopc Regulation of Positive_regulation of TNF 1 0.01 1.37 0.77
24 INT232613 Gopc Regulation of Cysltr1 1 0.02 0.58 0.68
25 INT125543 Arsa Negative_regulation of Phosphorylation of Nfkbia 1 0.00 0.52 0.68
26 INT214368 Pik3cb Regulation of Ubqln1 1 0.01 0.36 0.68
27 INT290549 Gopc Positive_regulation of Positive_regulation of Insr 1 0.01 0.06 0.65
28 INT290550 Gopc Positive_regulation of Insr 1 0.01 0.06 0.64
29 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
30 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
31 INT36320 PDYN Negative_regulation of Ctsb 1 0.00 0 0.61
32 INT223864 Tbs1 Positive_regulation of Gopc 1 0.03 0 0.61
33 INT271194 Binding of Bdnf and Gopc 1 0.03 0.49 0.6
34 INT271192 Binding of Gopc and Gtf3a 1 0.00 0.49 0.6
35 INT125546 Arsa Negative_regulation of Gene_expression of PTGS2 1 0.00 0.53 0.58
36 INT261482 Pik3cb Positive_regulation of Phosphorylation of Ephb1 1 0.23 0.67 0.58
37 INT18115 Binding of NPC1 and Oprd1 1 0.11 0 0.54
38 INT338038 Gopc Regulation of Gene_expression of F2r 1 0.08 0 0.52
39 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52
40 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52
41 INT274945 Binding of Fcgr1 and Gopc 1 0.02 0 0.49
42 INT242600 Binding of Gdnf and Gopc 1 0.06 0 0.49
43 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
44 INT215543 Negative_regulation of Trim33 Negative_regulation of Gopc 1 0.15 0.35 0.48
45 INT342693 Binding of Prkaca and Gopc 1 0.01 0.23 0.48
46 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
47 INT341226 Gopc Regulation of Shc3 1 0.00 0.68 0.45
48 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
49 INT341211 Gopc Regulation of Shc1 1 0.02 0.68 0.45
50 INT257806 Binding of Car1 and Gopc 1 0.13 0 0.43
51 INT347563 Abat Positive_regulation of Gopc 1 0.04 0.2 0.43
52 INT322395 Akt1 Regulation of Pik3cb 1 0.08 0 0.42
53 INT322394 Hist1h1t Positive_regulation of Pik3cb 1 0.01 0 0.42
54 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
55 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
56 INT288162 Igh-Dex Positive_regulation of Gopc 1 0.02 0.63 0.41
57 INT335643 CTSB Positive_regulation of PAR4 1 0.01 1.3 0.41
58 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
59 INT253482 H37 Positive_regulation of Gene_expression of Gopc 1 0.00 3.99 0.4
60 INT316632 Dao Negative_regulation of Gopc 1 0.09 0 0.4
61 INT282397 Binding of Irgm1 and Atg16l1 1 0.17 1.18 0.39
62 INT263433 Abl1 Regulation of Abl1 1 0.04 0.28 0.38
63 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
64 INT214374 Pik3cb Regulation of Gene_expression of Slc6a3 1 0.37 0.3 0.35
65 INT122755 Helt Positive_regulation of Pik3cb 1 0.00 0.19 0.35
66 INT356366 S1pr1 Regulation of Gopc 1 0.19 1.22 0.33
67 INT28006 NPC1 Negative_regulation of Positive_regulation of Rps6ka1 1 0.01 0.37 0.33
68 INT326089 Gopc Positive_regulation of Mmp9 1 0.03 0.63 0.33
69 INT28005 NPC1 Negative_regulation of Rps6ka1 1 0.01 0.45 0.32
70 INT315387 Adcyap1 Positive_regulation of Phosphorylation of Gopc 1 0.03 0.44 0.32
71 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32
72 INT253469 H37 Negative_regulation of Gene_expression of Gopc 1 0.00 1.5 0.31
73 INT272724 Ptger2 Positive_regulation of Positive_regulation of Gopc 1 0.01 0 0.3
74 INT272736 Ptger2 Positive_regulation of Gene_expression of Gopc 1 0.01 0 0.3
75 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
76 INT50107 Ei24 Positive_regulation of Localization of CTSB 3 0.00 0.6 0.29
77 INT334670 Gria2 Regulation of Gene_expression of Gopc 1 0.31 0.27 0.29
78 INT327706 Comt Regulation of Gopc 1 0.10 0 0.29
79 INT228530 Gopc Positive_regulation of Gene_expression of Nos2 2 0.22 0.67 0.28
80 INT258858 CTSB Positive_regulation of Gene_expression of IL8 1 0.00 0.64 0.28
81 INT253473 Ncapg2 Positive_regulation of Gene_expression of Gopc 1 0.08 1.26 0.27
82 INT223930 Binding of Akt1 and Pik3cb 1 0.07 0.35 0.26
83 INT307009 MT1JP Positive_regulation of Gene_expression of LAMP1 1 0.03 0.58 0.26
84 INT139980 Negative_regulation of CTSB Negative_regulation of Gene_expression of APP 1 0.15 0.7 0.26
85 INT139981 CTSB Negative_regulation of Gene_expression of APP 1 0.11 0.7 0.26
86 INT223929 Negative_regulation of Binding of Akt1 and Pik3cb 1 0.08 0.36 0.26
87 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
88 INT241401 VEGFA Positive_regulation of Gene_expression of Gopc 1 0.11 0.85 0.25
89 INT257805 Binding of Car3 and Gopc 1 0.18 0 0.25
90 INT326094 Akt1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.49 0.24
91 INT253771 Gopc Positive_regulation of Hmgb1 1 0.03 1.27 0.24
92 INT326092 Gene_expression of Akt1 Negative_regulation of Gopc 1 0.03 0.55 0.24
93 INT326093 Akt1 Positive_regulation of Gopc 1 0.03 0.43 0.23
94 INT202296 Binding of Slc18a3 and Gopc 1 0.02 0 0.23
95 INT229502 Binding of Vim and Gopc 1 0.05 0.42 0.23
96 INT289246 Il6 Positive_regulation of Gopc 1 0.06 1 0.22
97 INT196133 Binding of Gopc and Trpa1 1 0.12 0 0.22
98 INT187486 Binding of Prkag1 and Stk11 1 0.01 0.95 0.22
99 INT234724 Binding of NPC1 and Cxcl1 1 0.00 0.33 0.21
100 INT332018 Binding of C1qa and Gopc 1 0.23 0.87 0.21
101 INT338037 Ngf Positive_regulation of Gopc 1 0.09 0.26 0.21
102 INT314070 Gopc Negative_regulation of Il6 1 0.10 0.63 0.21
103 INT338049 Nrtn Positive_regulation of Gopc 1 0.06 0.26 0.21
104 INT317394 Binding of Stk11 and Amp1 1 0.04 0.89 0.21
105 INT228532 Positive_regulation of Gopc Positive_regulation of Ros1 1 0.03 0.55 0.2
106 INT228531 Gopc Positive_regulation of Ros1 1 0.03 0.55 0.2
107 INT229513 Positive_regulation of Binding of Ndel1 and Gopc 1 0.09 0.2 0.2
108 INT180441 Acot1 Positive_regulation of Gopc 1 0.03 0.43 0.19
109 INT180440 Positive_regulation of Acot1 Positive_regulation of Gopc 1 0.03 0.43 0.19
110 INT91862 RPA1 Negative_regulation of Transcription of ATG9B 1 0.03 0.46 0.19
111 INT352945 Fig4 Regulation of Negative_regulation of Pik3cb 1 0.03 0.38 0.19
112 INT254691 Gopc Positive_regulation of Positive_regulation of Map2k2 1 0.07 0.07 0.18
113 INT254698 Gopc Positive_regulation of Positive_regulation of Map2k1 1 0.06 0.07 0.18
114 INT195115 Gene_expression of Gopc Positive_regulation of Positive_regulation of F2r 1 0.17 1.67 0.18
115 INT245183 Binding of CTSB and TCF7L2 1 0.39 6.39 0.18
116 INT348756 Gopc Positive_regulation of Gene_expression of Mmp9 1 0.10 0.77 0.17
117 INT242603 Binding of Gfra1 and Gopc 1 0.01 0 0.17
118 INT242617 Binding of Gfra2 and Gopc 1 0.01 0 0.17
119 INT226209 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 0.10 1.16 0.17
120 INT274353 DST Regulation of Gopc 1 0.00 0 0.17
121 INT341213 Tas2r130 Positive_regulation of Gopc 1 0.00 0.2 0.17
122 INT326097 WAS Regulation of Gopc 1 0.01 0.55 0.16
123 INT242608 Binding of Nrtn and Gopc 1 0.05 0 0.16
124 INT321919 Binding of DAO and Gopc 1 0.02 0 0.16
125 INT86216 Hpd Regulation of NPC1 1 0.02 0.93 0.15
126 INT260363 Gopc Regulation of Oprd1 1 0.16 0.41 0.15
127 INT208264 Park7 Negative_regulation of Pten 1 0.16 1.16 0.15
128 INT314069 Gopc Negative_regulation of Stat1 1 0.14 0.95 0.15
129 INT184109 Binding of Gopc and Sh2 1 0.03 0 0.14
130 INT294763 Binding of Gopc and Cerk 1 0.14 0.37 0.14
131 INT341222 Tas2r130 Positive_regulation of Positive_regulation of Gopc 1 0.00 0.2 0.14
132 INT246683 exf Regulation of Gopc 1 0.01 0.2 0.14
133 INT184104 Binding of Socs3 and Gopc 1 0.10 0 0.14
134 INT306335 Gopc Positive_regulation of Localization of Cd14 1 0.17 0.19 0.13
135 INT328409 Nlrp1a Regulation of Gopc 1 0.04 0.37 0.13
136 INT205955 Gopc Regulation of Tdrd6 1 0.06 0.27 0.13
137 INT153738 TNFRSF11A Positive_regulation of SQSTM1 1 0.05 1.22 0.13
138 INT143661 Abl1 Regulation of Gpx1 1 0.19 0.56 0.12
139 INT253761 Hmgb1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.73 0.12
140 INT351974 Agt Positive_regulation of Gene_expression of Stk11 1 0.51 11.1 0.12
141 INT269055 Il6 Positive_regulation of Gene_expression of Gopc 1 0.21 0.06 0.12
142 INT287035 Gopc Positive_regulation of Prtn3 1 0.02 0.48 0.12
143 INT254490 Dtx1 Regulation of Gopc 1 0.04 0 0.12
144 INT354698 Binding of Dlg4 and Gopc 1 0.02 0.11 0.12
145 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
146 INT204996 Binding of Park7 and Pink1 2 0.34 1.09 0.11
147 INT354702 Binding of ASIC2 and Gopc 1 0.07 0.1 0.11
148 INT354714 Binding of ASIC3 and Gopc 1 0.08 0.1 0.11
149 INT291550 St8sia2 Positive_regulation of Pik3cb 1 0.05 0.36 0.11
150 INT317706 Binding of Gopc and Lmb2 1 0.00 0.14 0.11
151 INT316372 Positive_regulation of Gopc Positive_regulation of Ren1 1 0.06 0.13 0.11
152 INT316374 Gopc Positive_regulation of Ren1 1 0.06 0.13 0.11
153 INT189559 STK11 Positive_regulation of SNRK 1 0.03 0.36 0.11
154 INT286683 Gopc Positive_regulation of MBD2 1 0.01 1.07 0.11
155 INT195121 Gene_expression of Il1r1 Positive_regulation of Positive_regulation of Gopc 1 0.17 0.26 0.11
156 INT334761 Binding of Ednra and Gopc 1 0.03 0 0.11
157 INT271525 ITGB1 Positive_regulation of Gopc 1 0.02 0.57 0.11
158 INT316377 Gopc Positive_regulation of Positive_regulation of Ren1 1 0.06 0.13 0.11
159 INT171645 Negative_regulation of CTSB Positive_regulation of PRSS1 1 0.44 0.36 0.1
160 INT171644 CTSB Positive_regulation of PRSS1 1 0.52 0.36 0.1
161 INT342692 Binding of Gopc and Nav1 1 0.02 0.15 0.1
162 INT171648 Binding of CTSB and PRSS1 1 0.27 0.42 0.1
163 INT256061 Gopc Positive_regulation of Gene_expression of Vcam1 1 0.18 0.29 0.1
164 INT342694 Binding of Pdzd2 and Gopc 1 0.03 0.15 0.1
165 INT313308 Binding of SQSTM1 and KEAP1 1 0.46 1.16 0.1
166 INT317392 Negative_regulation of Binding of Stk11 and Amp1 1 0.05 0.34 0.1
167 INT256060 Gopc Positive_regulation of Vcam1 1 0.13 0.29 0.1
168 INT313301 SQSTM1 Regulation of Protein_catabolism of KEAP1 1 0.43 0.58 0.1
169 INT249117 Binding of Abl1 and Bcr 4 0.36 2.22 0.09
170 INT229506 Negative_regulation of Binding of Ndel1 and Gopc 1 0.08 0.35 0.09
171 INT325654 Binding of Nab1 and Gopc 1 0.04 0.63 0.09
172 INT190825 Cl Regulation of Gopc 1 0.00 0.52 0.09
173 INT229512 Binding of Nefl and Gopc 1 0.01 0.35 0.09
174 INT301143 Gopc Regulation of Gene_expression of TNF 1 0.07 0.56 0.09
175 INT229495 Negative_regulation of Binding of Nefl and Gopc 1 0.02 0.35 0.09
176 INT325653 Positive_regulation of Binding of Nab1 and Gopc 1 0.05 0.63 0.09
177 INT234605 Tlr4 Positive_regulation of Gene_expression of Gopc 2 0.16 0.15 0.08
178 INT221653 Binding of Myc and Gopc 2 0.12 0.51 0.08
179 INT204993 Eri1 Positive_regulation of Gene_expression of Pink1 1 0.22 0.61 0.08
180 INT246840 Binding of Ins1 and Gopc 1 0.05 0.15 0.08
181 INT346323 Binding of Gopc and Obfc1 1 0.01 0 0.08
182 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
183 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
184 INT340318 Gopc Regulation of Ntrk2 1 0.24 0.1 0.08
185 INT314064 Gopc Negative_regulation of Positive_regulation of Stat1 1 0.12 0.57 0.08
186 INT265222 Binding of Cd28 and Gopc 1 0.04 0 0.08
187 INT201543 Binding of NPC1 and RNASE1 1 0.07 1.33 0.08
188 INT246839 Binding of Irs1 and Gopc 1 0.16 0.15 0.08
189 INT92273 Binding of RGS19 and GNPTAB 1 0.03 0 0.07
190 INT249427 Binding of Gopc and Napa 1 0.10 0.12 0.07
191 INT346326 Binding of Gpi1 and Gopc 1 0.04 0.28 0.07
192 INT317398 Amp1 Positive_regulation of Phosphorylation of Stk11 1 0.05 0.22 0.07
193 INT308655 Binding of Lrp1 and Gopc 1 0.01 0.49 0.07
194 INT317391 Amp1 Positive_regulation of Stk11 1 0.05 0.22 0.07
195 INT350213 Binding of Rab33b and Atg16l1 1 0.37 0.28 0.07
196 INT308665 Binding of Apoe and Gopc 1 0.02 0.49 0.07
197 INT276980 Binding of Tlr2 and Gopc 1 0.14 0.28 0.07
198 INT247776 Ccrl2 Positive_regulation of Localization of Gopc 1 0.14 0.27 0.07
199 INT253139 Il6 Positive_regulation of Phosphorylation of Stk11 1 0.26 0.34 0.07
200 INT314068 Gopc Negative_regulation of Cxcl10 1 0.11 0.39 0.07

Single Events

The table below shows the top 100 pain related interactions that have been reported for autophagy. They are ordered first by their pain relevance and then by number of times they were reported in autophagy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55
2 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67
3 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4
4 INT173693 Localization of Gopc 249 0.65 70.49 38.81
5 INT172458 Regulation of Gopc 155 0.53 62.57 24.86
6 INT170444 Binding of Gopc 172 0.39 45.05 20.71
7 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93
8 INT120966 Positive_regulation of Pik3cb 34 0.68 15.15 16.59
9 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
10 INT94573 Negative_regulation of Pik3cb 42 0.50 15.83 15.4
11 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52
12 INT178306 Negative_regulation of Gene_expression of Gopc 71 0.37 26.43 9.74
13 INT3622 Regulation of CTSB 34 0.58 16.08 8.76
14 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
15 INT175526 Phosphorylation of Gopc 73 0.53 21.08 7.86
16 INT7168 Positive_regulation of Ctsb 9 0.70 0.3 7.58
17 INT200874 Positive_regulation of Localization of Gopc 27 0.38 5.69 7.5
18 INT170381 Transcription of Gopc 59 0.60 15.96 6.82
19 INT170296 Regulation of Gene_expression of Gopc 33 0.38 12.49 6
20 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
21 INT50105 Localization of CTSB 29 0.78 10.98 5.21
22 INT3476 Phosphorylation of Npc1 7 0.48 0 4.84
23 INT7170 Positive_regulation of Positive_regulation of Ctsb 1 0.40 0 4.76
24 INT204971 Gene_expression of Pink1 42 0.77 23.95 4.75
25 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
26 INT76227 Binding of NPC1 30 0.41 32.31 4.05
27 INT116643 Phosphorylation of Pik3cb 12 0.80 4.73 3.87
28 INT174277 Positive_regulation of Positive_regulation of Gopc 23 0.33 8.08 3.73
29 INT170899 Negative_regulation of Positive_regulation of Gopc 16 0.19 5.46 3.71
30 INT175531 Positive_regulation of Phosphorylation of Gopc 11 0.33 2.53 3.54
31 INT20265 Gene_expression of Ctsb 3 0.47 1.01 3.52
32 INT116645 Regulation of Pik3cb 11 0.41 3.78 3.43
33 INT200872 Negative_regulation of Localization of Gopc 16 0.22 5.61 3.3
34 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
35 INT30435 Gene_expression of Ei24 6 0.58 1.5 3.05
36 INT175524 Negative_regulation of Phosphorylation of Gopc 14 0.20 2.74 2.96
37 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
38 INT59342 Negative_regulation of NPC1 20 0.44 20.21 2.79
39 INT110980 Gene_expression of CTSB 17 0.45 8.02 2.69
40 INT73028 Positive_regulation of Transcription of Ctsb 1 0.55 1.53 2.54
41 INT59135 Positive_regulation of CTSB 15 0.67 7.53 2.53
42 INT3475 Regulation of Phosphorylation of Npc1 3 0.36 0 2.45
43 INT163544 Binding of Psen1 40 0.36 15.28 2.42
44 INT37427 Positive_regulation of Gene_expression of Ctsb 2 0.37 1.02 2.33
45 INT7173 Regulation of Positive_regulation of Ctsb 1 0.49 0 2.29
46 INT128745 Positive_regulation of Positive_regulation of Pik3cb 4 0.56 0.95 2.24
47 INT30436 Negative_regulation of Ei24 4 0.56 3.8 2.15
48 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
49 INT157305 Gene_expression of Map1lc3a 47 0.75 18.04 1.93
50 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
51 INT169862 Regulation of NPC1 13 0.53 13.61 1.84
52 INT78665 Gene_expression of Irgm1 12 0.65 3.17 1.83
53 INT149335 Gene_expression of Pik3cb 10 0.57 2.93 1.82
54 INT96746 Gene_expression of Lamp1 2 0.03 1.82 1.81
55 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
56 INT207202 Positive_regulation of Transcription of Gopc 10 0.16 1.76 1.71
57 INT39290 Positive_regulation of Ei24 3 0.45 3.27 1.7
58 INT50106 Positive_regulation of Localization of CTSB 9 0.33 3.15 1.69
59 INT73027 Transcription of Ctsb 1 0.56 1.01 1.68
60 INT200873 Positive_regulation of Negative_regulation of Gopc 4 0.36 0.81 1.59
61 INT42585 Positive_regulation of Phosphorylation of Npc1 3 0.19 0 1.59
62 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
63 INT18114 Gene_expression of NPC1 45 0.66 57.85 1.44
64 INT42335 Binding of CTSB 11 0.34 5.98 1.37
65 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
66 INT121723 Regulation of Positive_regulation of Pik3cb 1 0.44 0.61 1.29
67 INT164706 Positive_regulation of Park7 2 0.50 2.28 1.28
68 INT170900 Regulation of Positive_regulation of Gopc 10 0.20 3.44 1.24
69 INT166628 Positive_regulation of Gene_expression of Becn1 2 0.67 1.03 1.23
70 INT166632 Gene_expression of Becn1 2 0.75 1.02 1.22
71 INT215091 Regulation of Localization of Gopc 6 0.27 1.18 1.2
72 INT178480 Positive_regulation of Irgm1 7 0.13 5.91 1.15
73 INT43295 Regulation of Arsa 1 0.43 0 1.15
74 INT20317 Localization of Ctsb 3 0.81 0.68 1.12
75 INT59136 Negative_regulation of Positive_regulation of CTSB 3 0.41 2.02 1.11
76 INT106952 Positive_regulation of NPC1 23 0.43 22.9 0.94
77 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
78 INT166630 Negative_regulation of Localization of Becn1 1 0.41 0.51 0.88
79 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87
80 INT166626 Localization of Becn1 1 0.76 0.5 0.87
81 INT166633 Binding of Becn1 1 0.45 0.5 0.86
82 INT166629 Negative_regulation of Binding of Becn1 1 0.41 0.5 0.86
83 INT7175 Negative_regulation of Positive_regulation of Ctsb 1 0.34 0 0.86
84 INT157303 Positive_regulation of Gene_expression of Map1lc3a 15 0.53 4.12 0.85
85 INT166631 Positive_regulation of Becn1 1 0.41 0.52 0.84
86 INT176467 Gene_expression of Arsa 1 0.58 2.62 0.83
87 INT79941 Negative_regulation of Npc1 9 0.59 3.97 0.82
88 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
89 INT157302 Positive_regulation of Map1lc3a 27 0.66 11.31 0.79
90 INT194633 Negative_regulation of Gene_expression of Pik3cb 3 0.21 1.83 0.79
91 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
92 INT199573 Gene_expression of Abl1 33 0.65 20.79 0.75
93 INT241499 Binding of Abl1 23 0.47 8.86 0.75
94 INT176445 Protein_catabolism of Gopc 23 0.76 7.57 0.75
95 INT204969 Negative_regulation of Pink1 1 0.58 7.03 0.75
96 INT79243 Negative_regulation of Localization of CTSB 2 0.57 1.35 0.73
97 INT282385 Binding of Irgm1 2 0.20 3.18 0.7
98 INT20318 Regulation of Ctsb 1 0.54 0.19 0.69
99 INT191931 Negative_regulation of Binding of Gopc 13 0.29 4.83 0.68
100 INT125542 Phosphorylation of Arsa 1 0.02 0.52 0.67
101 INT243593 Negative_regulation of Transcription of Gopc 4 0.18 0.14 0.65
102 INT120963 Negative_regulation of Negative_regulation of Pik3cb 2 0.17 1.4 0.64
103 INT43062 Positive_regulation of Positive_regulation of Ei24 1 0.39 3.57 0.64
104 INT170284 Gene_expression of Arsb 9 0.65 9.12 0.63
105 INT59137 Protein_catabolism of CTSB 5 0.96 3.92 0.62
106 INT247751 Positive_regulation of Binding of Gopc 8 0.25 0.75 0.61
107 INT296589 Localization of Pink1 1 0.08 0.65 0.61
108 INT282380 Binding of Atg16l1 4 0.38 2.06 0.58
109 INT188448 Negative_regulation of SQSTM1 4 0.53 3.75 0.55
110 INT188444 Binding of SQSTM1 5 0.44 4.69 0.54
111 INT120961 Positive_regulation of Phosphorylation of Pik3cb 3 0.26 1.02 0.53
112 INT174278 Negative_regulation of Regulation of Gopc 2 0.20 0.61 0.53
113 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
114 INT253108 Phosphorylation of Stk11 4 0.65 2.13 0.52
115 INT126367 Positive_regulation of Gene_expression of CTSB 3 0.04 1.57 0.52
116 INT193736 Regulation of Positive_regulation of CTSB 1 0.04 1.13 0.52
117 INT230238 Binding of Pik3cb 6 0.21 2.27 0.51
118 INT170346 Gene_expression of Npc1 18 0.78 7.69 0.48
119 INT3477 Regulation of Npc1 6 0.45 1.87 0.47
120 INT272700 Regulation of Transcription of Gopc 2 0.29 0.8 0.47
121 INT157300 Negative_regulation of Positive_regulation of Map1lc3a 1 0.00 0.61 0.45
122 INT157306 Positive_regulation of Positive_regulation of Map1lc3a 3 0.35 1.21 0.44
123 INT234249 Regulation of PSEN1 6 0.37 2.21 0.43
124 INT156997 Localization of NPC1 19 0.64 30 0.42
125 INT234257 Regulation of Gene_expression of PSEN1 6 0.44 1.98 0.42
126 INT193856 Localization of Psen1 19 0.73 9.79 0.41
127 INT157301 Negative_regulation of Map1lc3a 5 0.28 3.2 0.41
128 INT99614 Gene_expression of LAMP1 7 0.75 4.57 0.39
129 INT120968 Negative_regulation of Phosphorylation of Pik3cb 1 0.12 0.89 0.39
130 INT312037 Gene_expression of BECN1 2 0.33 1.5 0.37
131 INT194629 Positive_regulation of Gene_expression of Pik3cb 4 0.24 0.67 0.36
132 INT177773 Localization of PSEN1 4 0.73 0.89 0.36
133 INT97859 Localization of Npc1 12 0.75 6.66 0.35
134 INT190900 Binding of Arsb 5 0.35 17.18 0.35
135 INT351970 Gene_expression of Stk11 1 0.75 33.89 0.35
136 INT4133 Binding of Npc1 14 0.47 8.24 0.33
137 INT32509 Positive_regulation of Npc1 6 0.50 2.24 0.33
138 INT237038 Gene_expression of Becn1 18 0.36 13.68 0.31
139 INT43060 Binding of Ei24 1 0.34 1.73 0.31
140 INT310681 Negative_regulation of ARSB 1 0.56 6.95 0.29
141 INT126366 Regulation of Binding of CTSB 1 0.01 0.31 0.28
142 INT194031 Regulation of SQSTM1 2 0.41 2.07 0.27
143 INT316045 Negative_regulation of Negative_regulation of Psen1 1 0.42 1.58 0.27
144 INT141896 Positive_regulation of SQSTM1 6 0.50 5.58 0.26
145 INT201565 Positive_regulation of Gene_expression of NPC1 5 0.43 5.94 0.26
146 INT42784 Localization of Ei24 2 0.77 1.17 0.26
147 INT349301 Negative_regulation of PARK7 1 0.41 3.44 0.26
148 INT261676 Negative_regulation of Positive_regulation of PSEN1 1 0.36 1.59 0.25
149 INT214364 Positive_regulation of Negative_regulation of Pik3cb 1 0.42 0.19 0.25
150 INT309880 Positive_regulation of Localization of NPC1 1 0.04 1.06 0.25
151 INT120969 Negative_regulation of Positive_regulation of Pik3cb 2 0.19 0.69 0.24
152 INT32508 Positive_regulation of Positive_regulation of Npc1 2 0.47 0.67 0.23
153 INT313313 Positive_regulation of Gene_expression of SQSTM1 1 0.63 1.25 0.23
154 INT241498 Regulation of Abl1 8 0.32 6.46 0.22
155 INT170285 Positive_regulation of Gene_expression of Arsb 1 0.40 0.65 0.21
156 INT344156 Positive_regulation of Gene_expression of Irgm1 1 0.02 0.71 0.21
157 INT92276 Gene_expression of RGS19 1 0.73 0 0.21
158 INT92274 Transcription of RGS19 1 0.65 0 0.21
159 INT254878 Localization of Map1lc3a 5 0.57 3.32 0.2
160 INT181508 Regulation of Regulation of Psen1 2 0.33 0.51 0.2
161 INT344159 Positive_regulation of Positive_regulation of Irgm1 1 0.03 0.33 0.2
162 INT346897 Positive_regulation of Atg16l1 1 0.16 0.57 0.19
163 INT351969 Positive_regulation of Gene_expression of Stk11 1 0.67 21.03 0.19
164 INT45092 Positive_regulation of Localization of Ctsb 1 0.50 0 0.19
165 INT147190 Positive_regulation of Lamp1 1 0.35 0.34 0.19
166 INT91867 Transcription of ATG9B 1 0.03 0.46 0.19
167 INT346898 Regulation of Binding of Atg16l1 1 0.09 0.75 0.19
168 INT188446 Gene_expression of SQSTM1 5 0.71 5.34 0.18
169 INT43059 Negative_regulation of Localization of Ei24 1 0.56 0.85 0.18
170 INT204987 Binding of Pink1 3 0.37 4.72 0.17
171 INT286317 Positive_regulation of Transcription of Psen1 1 0.37 0.32 0.17
172 INT42785 Regulation of Ei24 1 0.26 0.65 0.17
173 INT199561 Positive_regulation of Gene_expression of Abl1 8 0.36 4.77 0.16
174 INT204983 Positive_regulation of Gene_expression of Pink1 1 0.50 2.03 0.16
175 INT196603 Gene_expression of STK11 5 0.55 6.75 0.15
176 INT165481 Negative_regulation of Gene_expression of Map1lc3a 7 0.45 2.55 0.14
177 INT204975 Positive_regulation of Pink1 7 0.69 5.17 0.14
178 INT189633 Regulation of STK11 3 0.41 3.57 0.14
179 INT170340 Regulation of Gene_expression of Npc1 2 0.17 0.38 0.14
180 INT92275 Positive_regulation of RGS19 1 0.47 0 0.14
181 INT313318 Negative_regulation of Localization of SQSTM1 1 0.39 0.59 0.14
182 INT281868 Negative_regulation of Park7 1 0.00 1.69 0.14
183 INT310677 Localization of ARSB 1 0.71 5.72 0.14
184 INT313320 Localization of SQSTM1 1 0.68 0.59 0.14
185 INT221105 Negative_regulation of Irgm1 3 0.13 1.31 0.13
186 INT106227 Binding of STK11 3 0.42 3.13 0.13
187 INT189583 Transcription of STK11 2 0.49 4.43 0.13
188 INT330233 Positive_regulation of Stk11 2 0.67 8.15 0.13
189 INT336359 Positive_regulation of Phosphorylation of Psen1 1 0.33 0.4 0.13
190 INT92278 Regulation of Transcription of RGS19 1 0.42 0 0.13
191 INT336361 Phosphorylation of Psen1 1 0.54 0.34 0.13
192 INT151587 Positive_regulation of Stk11 2 0.38 0.44 0.12
193 INT244122 Negative_regulation of Arsa 1 0.42 0 0.12
194 INT349300 Gene_expression of PARK7 1 0.75 8.65 0.12
195 INT310680 Gene_expression of ARSB 1 0.64 6.28 0.12
196 INT313312 Positive_regulation of Binding of SQSTM1 1 0.46 0.44 0.11
197 INT204986 Gene_expression of Park7 5 0.38 5.48 0.1
198 INT201694 Negative_regulation of Gene_expression of PSEN1 3 0.41 2.31 0.1
199 INT173981 Gene_expression of Park7 2 0.56 0.73 0.1
200 INT3649 Positive_regulation of Arsa 1 0.50 0 0.1
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