GO:0006915

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Name apoptotic process
Categary Process
Go Slim No
Go Link GO:0006915
Unique Molecular Interactions 8770
Total Molecular Interactions 11666
Total Single Events 99401
Pain Genes Associated 541

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for apoptotic process. They are ordered first by their pain relevance and then by number of times they were reported for apoptotic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10161 Binding of Cck and Penk 6 0.53 0.97 11.15
2 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
3 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
4 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
5 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
6 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
7 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
8 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
9 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
10 INT51497 Cck Negative_regulation of Localization of Trim13 1 0.34 0 4.53
11 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
12 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
13 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
14 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17
15 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
16 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
17 INT69938 Cck Positive_regulation of Localization of Abat 2 0.29 0 3.78
18 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
19 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
20 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
21 INT69823 Binding of GHR and RYBP 1 0.01 0 3.23
22 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
23 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
24 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
25 INT28235 Binding of Cck and Gast 5 0.38 0.73 2.96
26 INT69937 Cck Positive_regulation of Abat 2 0.31 0 2.88
27 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
28 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81
29 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
30 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
31 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
32 INT30133 Binding of Cck and Penk 1 0.27 2.49 2.71
33 INT151381 St8sia1 Positive_regulation of Cck 1 0.19 0.45 2.7
34 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
35 INT91350 Binding of Pla2g4a and RYBP 1 0.00 1.15 2.65
36 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
37 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
38 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
39 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
40 INT111787 Cck Regulation of Gene_expression of Npr1 1 0.22 1.68 2.57
41 INT111789 Cck Regulation of Gene_expression of Penk 1 0.49 1.68 2.57
42 INT111786 Penk Regulation of Gene_expression of Cck 1 0.49 1.66 2.55
43 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
44 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
45 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
46 INT214144 Cck Positive_regulation of Pomc 1 0.15 0.94 2.39
47 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
48 INT153728 RYBP Positive_regulation of Gpt 3 0.03 2.01 2.36
49 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
50 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
51 INT214159 Cck Positive_regulation of Nts 1 0.03 0.93 2.34
52 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
53 INT139723 PROC Positive_regulation of MAPK8 1 0.01 2.98 2.33
54 INT14781 Cck Regulation of Gast 3 0.38 0.28 2.3
55 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
56 INT321474 Binding of Slc6a2 and Ubqln1 1 0.00 0.8 2.27
57 INT321477 Binding of Ubqln1 and Flvcr2 1 0.00 0.81 2.26
58 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
59 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
60 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
61 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
62 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
63 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
64 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
65 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
66 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
67 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
68 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
69 INT5486 Oprd1 Regulation of Cck 1 0.21 0 2.16
70 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
71 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
72 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
73 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
74 INT63919 Binding of Cck and Insrr 1 0.01 0 2.08
75 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
76 INT296277 Binding of Car2 and Kcnip3 5 0.18 1.09 2.06
77 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06
78 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
79 INT88883 IRF6 Positive_regulation of Nfkb1 1 0.11 0.53 2.01
80 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
81 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
82 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
83 INT334532 Sema3a Negative_regulation of Gene_expression of Nrp1 1 0.19 7.58 2
84 INT53751 Positive_regulation of Cyp2e1 Positive_regulation of RYBP 1 0.14 0.89 1.98
85 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
86 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
87 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
88 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
89 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
90 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
91 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
92 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
93 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89
94 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
95 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
96 INT169346 Nxn Negative_regulation of Dynll1 1 0.06 1.22 1.87
97 INT203044 Binding of PDCD1 and DTHD1 1 0.02 3.19 1.87
98 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
99 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
100 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
101 INT82867 Cck Regulation of Localization of Pgc 1 0.05 0 1.83
102 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
103 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
104 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
105 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78
106 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78
107 INT115048 Kcnip3 Regulation of Gene_expression of Pdyn 2 0.27 0.71 1.78
108 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
109 INT116092 TFF2 Positive_regulation of NFKB1 1 0.17 0.06 1.77
110 INT149491 PNOC Negative_regulation of Gene_expression of CD14 1 0.40 0.37 1.76
111 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75
112 INT190981 Binding of Npy and Scn2a1 1 0.10 0 1.75
113 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73
114 INT92369 Binding of CYP2D6 and RYBP 1 0.25 0.15 1.73
115 INT282398 Binding of Mefv and Nlrp3 1 0.40 6.8 1.72
116 INT139190 Binding of Fadd and Fas 4 0.38 2.65 1.71
117 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
118 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
119 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
120 INT18786 Binding of Adra2a and Nisch 2 0.19 0 1.7
121 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
122 INT119413 SEMA6A Positive_regulation of TNFRSF11A 1 0.10 2.48 1.7
123 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
124 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
125 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67
126 INT347396 RYBP Positive_regulation of Binding of Sdcbp 1 0.00 0.92 1.66
127 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
128 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
129 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
130 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
131 INT90658 Abat Regulation of Localization of Cck 2 0.24 0 1.64
132 INT30743 Cck Regulation of Localization of Acot1 1 0.02 0 1.64
133 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
134 INT67966 Cck Positive_regulation of Adarb1 2 0.03 0 1.63
135 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
136 INT247281 GLC1N Negative_regulation of HRAS 1 0.02 1.98 1.62
137 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
138 INT266768 NGF Positive_regulation of Localization of SFTPA1 1 0.01 1.65 1.6
139 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
140 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
141 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
142 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
143 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
144 INT118515 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1 1 0.27 0.56 1.58
145 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
146 INT81709 POMC Regulation of Gene_expression of ITGB2 1 0.40 0.34 1.57
147 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
148 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56
149 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
150 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
151 INT81715 POMC Regulation of ITGB2 1 0.40 0.34 1.55
152 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
153 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
154 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
155 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
156 INT100784 RYBP Positive_regulation of CYP3A4 1 0.44 0 1.54
157 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
158 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
159 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
160 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
161 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
162 INT42001 Cck Regulation of Vip 1 0.28 0 1.51
163 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
164 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
165 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5
166 INT166676 Binding of PRKCA and UGT1A6 1 0.30 0 1.5
167 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
168 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
169 INT42000 Trpv1 Positive_regulation of Cck 1 0.04 0 1.49
170 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48
171 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48
172 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48
173 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
174 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
175 INT118812 Cck Positive_regulation of Rvm 1 0.21 0.65 1.46
176 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
177 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
178 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 0.37 0.17 1.44
179 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43
180 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
181 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
182 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
183 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
184 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
185 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
186 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
187 INT134679 FSCN1 Positive_regulation of MAPK8 1 0.01 0.56 1.39
188 INT27123 Binding of Pomc and Cck 2 0.31 0 1.38
189 INT161191 CRX Regulation of Gene_expression of Trib3 1 0.00 2 1.38
190 INT50706 Phax Positive_regulation of Localization of Trib3 1 0.04 0.28 1.38
191 INT161185 NMS Regulation of Gene_expression of Trib3 1 0.03 2 1.38
192 INT167169 Nfkb1 Regulation of Gene_expression of Crp 1 0.09 1.76 1.38
193 INT30089 Cck Regulation of Localization of Oxt 2 0.45 0.19 1.36
194 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
195 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35
196 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
197 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
198 INT250934 Binding of BDNF and NGF 3 0.39 0.62 1.34
199 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 0.12 0.16 1.34
200 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34

Single Events

The table below shows the top 100 pain related interactions that have been reported for apoptotic process. They are ordered first by their pain relevance and then by number of times they were reported in apoptotic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT287 Localization of Cck 518 0.81 86.84 364.04
3 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
5 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
6 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41
7 INT6852 Localization of TNF 883 0.81 705.95 270.84
8 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
9 INT3948 Regulation of Cck 291 0.62 58.07 255.88
10 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92
11 INT6481 Binding of TNF 624 0.48 510.2 214.82
12 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
13 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
14 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
15 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
16 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78
17 INT2366 Binding of Cck 192 0.48 30.64 163.46
18 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
19 INT9660 Regulation of TNF 363 0.62 312.94 139.99
20 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
21 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
22 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
23 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06
24 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
25 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
26 INT65500 Gene_expression of App 605 0.78 429.94 98.31
27 INT2862 Positive_regulation of Localization of Cck 108 0.70 20.75 94.25
28 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
29 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
30 INT10166 Localization of Tnf 237 0.81 153.95 88.64
31 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01
32 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32
33 INT22967 Positive_regulation of RYBP 94 0.56 37.04 85.92
34 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48
35 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
36 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45
37 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
38 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
39 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
40 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
41 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
42 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
43 INT6849 Localization of IL1B 229 0.81 112.56 69.63
44 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
45 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
46 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
47 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
48 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
49 INT18883 Negative_regulation of RYBP 53 0.56 21.14 57.52
50 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
51 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5
52 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
53 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
54 INT8153 Regulation of Localization of Cck 52 0.62 11.22 54.83
55 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
56 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
57 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
58 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
59 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
60 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
61 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
62 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
63 INT6544 Negative_regulation of Localization of Cck 67 0.59 8.05 47.23
64 INT5025 Positive_regulation of Gene_expression of Cck 63 0.70 10.96 47.11
65 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49
66 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
67 INT4656 Localization of RYBP 49 0.77 5.28 46.21
68 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
69 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33
70 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
71 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
72 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
73 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9
74 INT26788 Gene_expression of Gad1 93 0.78 27.05 42.71
75 INT11180 Binding of RYBP 52 0.46 13.86 42.53
76 INT13354 Transcription of TNF 108 0.72 85.81 42.32
77 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
78 INT81251 Gene_expression of Trpv2 78 0.78 28.27 41.76
79 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
80 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38
81 INT7824 Regulation of Cck 39 0.62 5.31 39.28
82 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
83 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92
84 INT18774 Gene_expression of RYBP 67 0.65 47.66 37.59
85 INT12159 Transcription of Cck 46 0.72 9.36 37.58
86 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81
87 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75
88 INT64436 Gene_expression of P2rx1 93 0.78 32.69 36.12
89 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
90 INT6484 Binding of IL1B 122 0.47 75.84 35.07
91 INT7833 Positive_regulation of Cck 33 0.70 8.54 34.21
92 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
93 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05
94 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13
95 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
96 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88
97 INT9796 Gene_expression of Cck 63 0.78 11.44 32.09
98 INT10453 Positive_regulation of Gad1 65 0.70 10.75 31.9
99 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
100 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72
101 INT35406 Localization of Tnf 94 0.81 64.63 31.65
102 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
103 INT70776 Positive_regulation of P2rx1 62 0.62 32.55 30.75
104 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
105 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27
106 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11
107 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
108 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
109 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
110 INT1616 Regulation of Gad1 46 0.61 10.2 28.64
111 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
112 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43
113 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31
114 INT56072 Negative_regulation of NFKB1 94 0.59 53.16 28.19
115 INT233457 Gene_expression of Gpr65 56 0.68 26.57 27.94
116 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
117 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
118 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9
119 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
120 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
121 INT12681 Regulation of Trib3 76 0.53 23.92 26.58
122 INT7832 Localization of Cck 39 0.81 6.81 26.54
123 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
124 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2
125 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
126 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
127 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
128 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11
129 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
130 INT19986 Negative_regulation of Cck 31 0.59 4.32 24.99
131 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
132 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71
133 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
134 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
135 INT8518 Localization of Ifng 53 0.81 36.68 24.13
136 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
137 INT20003 Gene_expression of Scn2a1 125 0.71 8.78 23.94
138 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
139 INT7827 Binding of Cck 32 0.48 4.66 23.73
140 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
141 INT66758 Binding of Nfkb1 97 0.48 50.65 23.65
142 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62
143 INT18884 Regulation of RYBP 25 0.38 11.43 23.2
144 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16
145 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09
146 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
147 INT55170 Gene_expression of NFKB1 97 0.77 52.75 23.04
148 INT71875 Localization of Nfkb1 92 0.78 48.13 22.94
149 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
150 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71
151 INT66208 Positive_regulation of Positive_regulation of NFKB1 45 0.68 20.17 22.62
152 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39
153 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38
154 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
155 INT15326 Phosphorylation of Trib3 83 0.55 30.96 22.27
156 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
157 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
158 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68
159 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58
160 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48
161 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94
162 INT52529 Regulation of Nfkb1 48 0.61 26.2 20.89
163 INT11625 Localization of App 98 0.78 55.46 20.86
164 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
165 INT69877 Positive_regulation of Positive_regulation of Nfkb1 53 0.68 31.44 20.7
166 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
167 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48
168 INT16326 Transcription of Gad1 58 0.71 15.78 20.45
169 INT79805 Phosphorylation of PRKCA 57 0.81 23.33 20.41
170 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
171 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98
172 INT16794 Binding of App 103 0.48 64.87 19.79
173 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
174 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67
175 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
176 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
177 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
178 INT9128 Regulation of Gene_expression of Cck 27 0.62 6.55 19.45
179 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
180 INT65502 Regulation of App 77 0.62 52.05 19.44
181 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
182 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19
183 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
184 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01
185 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
186 INT69592 Positive_regulation of PSMD1 27 0.70 17.83 18.98
187 INT19509 Localization of Ifng 55 0.78 28.25 18.67
188 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
189 INT10286 Positive_regulation of Positive_regulation of Cck 20 0.70 4.05 18.46
190 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
191 INT30197 Positive_regulation of Ubqln1 26 0.08 2.07 18.28
192 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
193 INT151747 Positive_regulation of PSMD2 26 0.68 17.48 17.89
194 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88
195 INT116950 Negative_regulation of MAPK8 103 0.57 44.48 17.53
196 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
197 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
198 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15
199 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07
200 INT276855 Positive_regulation of Gene_expression of Gpr65 1 0.61 17.04 16.96
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