GO:0006940

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Name regulation of smooth muscle contraction
Categary Process
Go Slim No
Go Link GO:0006940
Unique Molecular Interactions 204
Total Molecular Interactions 338
Total Single Events 2785
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of smooth muscle contraction. They are ordered first by their pain relevance and then by number of times they were reported for regulation of smooth muscle contraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
2 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
3 INT153533 NMS Regulation of Gene_expression of Ephb1 1 0.48 3.96 1.93
4 INT161188 NMS Regulation of Gene_expression of Rvm 1 0.03 2 1.39
5 INT161185 NMS Regulation of Gene_expression of Trib3 1 0.03 2 1.38
6 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
7 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
8 INT146879 CRX Regulation of NMS 2 0.02 1.86 1.17
9 INT160653 Binding of P2rx1 and Ptgfr 1 0.28 0.66 1.14
10 INT215584 P2rx1 Regulation of Localization of Gabrg1 1 0.01 0 0.92
11 INT161183 NMS Positive_regulation of Gene_expression of Bdnf 1 0.40 1.3 0.67
12 INT102350 P2rx1 Negative_regulation of Localization of Il6 1 0.32 0 0.67
13 INT153532 NMS Regulation of Gene_expression of Fos 1 0.23 1.33 0.67
14 INT161184 NMS Positive_regulation of Gene_expression of Ntrk2 1 0.55 1.3 0.67
15 INT151783 Regulation of Binding of Calca and P2rx1 1 0.42 0.51 0.64
16 INT151778 Binding of Calca and P2rx1 1 0.35 0.5 0.64
17 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
18 INT260845 Binding of Flt1 and Positive_regulation of Gene_expression of TNF 1 0.36 1.5 0.56
19 INT146877 NMS Positive_regulation of Ngf 1 0.39 0.78 0.52
20 INT64514 Binding of TNNI3 and Mb 2 0.03 1.64 0.5
21 INT210878 Binding of FLT1 and HBM 1 0.06 0.83 0.5
22 INT153534 Binding of Ephb1 and NMS 1 0.29 1.13 0.5
23 INT152281 Binding of P2rx1 and Trpv1 1 0.15 0.42 0.49
24 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
25 INT69637 Binding of CAV1 and Zfp354a 1 0.00 0 0.46
26 INT151782 Phosphorylation of Creb1 Positive_regulation of Gene_expression of P2rx1 1 0.41 0.07 0.44
27 INT151781 Calca Positive_regulation of Gene_expression of P2rx1 1 0.50 0.07 0.44
28 INT146878 NMS Regulation of Ngf 1 0.23 0.81 0.43
29 INT98214 Negative_regulation of Binding of TNNI3 and Mb 1 0.02 0.91 0.41
30 INT85037 Binding of Cct2 and Chrna3 1 0.00 0.15 0.38
31 INT196883 Prkca Regulation of P2rx1 1 0.05 0.45 0.31
32 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
33 INT258857 Binding of P2rx1 and P2ry2 1 0.22 0.81 0.29
34 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
35 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27
36 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
37 INT193031 CHRM2 Positive_regulation of ROCK1 1 0.00 0.12 0.24
38 INT193029 CHRM2 Positive_regulation of RHOA 1 0.01 0.12 0.24
39 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
40 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22
41 INT52629 Binding of AVP and NMS 1 0.04 1.04 0.21
42 INT151424 Tfrc Negative_regulation of Positive_regulation of Tnni3 1 0.21 0.98 0.2
43 INT260827 Binding of Flt1 and Pgf 1 0.27 0.6 0.2
44 INT261628 Binding of CHRNA3 and MAOA 1 0.22 1.61 0.17
45 INT142332 Binding of SERPINH1 and TNNI3 1 0.03 1.05 0.17
46 INT220520 Ugt1a6b Positive_regulation of Gene_expression of Cav1 1 0.01 0.81 0.17
47 INT222877 Chrm2 Negative_regulation of EPHB2 1 0.05 0.66 0.17
48 INT264277 Binding of Car2 and P2rx1 1 0.10 0 0.16
49 INT141322 Binding of PAPPA and TNNI3 1 0.09 0.98 0.16
50 INT264276 Binding of Ednrb and P2rx1 1 0.00 0.17 0.16
51 INT302930 Binding of Pnp and Chrm2 1 0.00 0.64 0.15
52 INT155644 Binding of CAV1 and HSD11B1 1 0.39 0.77 0.15
53 INT172256 Binding of NMU and GPR87 1 0.31 0 0.14
54 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14
55 INT172241 Binding of NMUR1 and NMU 1 0.40 0 0.14
56 INT336665 Binding of P2rx1 and P2rx2 1 0.07 0 0.14
57 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
58 INT227953 Chrm2 Regulation of Chrm5 1 0.21 0.33 0.13
59 INT227956 Drd2 Regulation of Chrm2 1 0.07 0.38 0.13
60 INT260834 Negative_regulation of Binding of VEGFA and Flt1 1 0.15 0.5 0.13
61 INT271345 Negative_regulation of PIGF Negative_regulation of FLT1 1 0.02 1.17 0.13
62 INT228110 Chrm2 Positive_regulation of Localization of Il10 1 0.33 0.66 0.13
63 INT227958 Chrm2 Regulation of Localization of Drd2 1 0.17 0.38 0.13
64 INT158014 Binding of FLT1 and PGF 2 0.27 0.9 0.12
65 INT230760 VEGFA Positive_regulation of Flt1 1 0.03 0.96 0.12
66 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
67 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12
68 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11
69 INT236401 Binding of Flt1 and Mthfs 1 0.01 0.28 0.11
70 INT236403 Binding of Flt1 and Negative_regulation of Gene_expression of VEGFA 1 0.04 0.3 0.11
71 INT207683 Chrnb4 Positive_regulation of Htr3b 1 0.26 0.31 0.1
72 INT207682 Chrnb4 Positive_regulation of Hcn4 1 0.35 0.29 0.1
73 INT207681 Chrnb4 Positive_regulation of Scn2b 1 0.02 0.32 0.1
74 INT220517 Negative_regulation of Ugt1a6b Positive_regulation of Cav1 1 0.01 0.35 0.1
75 INT207684 Chrnb4 Positive_regulation of Htr3a 1 0.22 0.3 0.1
76 INT64513 Positive_regulation of Binding of TNNI3 and Mb 1 0.03 0.73 0.09
77 INT143399 Binding of INSRR and NMU 1 0.01 0.12 0.09
78 INT318210 MUC5AC Negative_regulation of Phosphorylation of Flt1 1 0.07 0.98 0.09
79 INT302977 Binding of Cav1 and Smpd2 1 0.08 0.71 0.09
80 INT158012 Binding of ENG and FLT1 1 0.21 0.39 0.09
81 INT220511 Cav1 Negative_regulation of Transcription of Ccnd1 1 0.03 0.83 0.09
82 INT261625 Binding of CHRNA3 and CPD 1 0.07 0.35 0.08
83 INT320785 Binding of Flt1 and Kdr 1 0.15 0.67 0.08
84 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
85 INT143118 TFF2 Regulation of FLT1 1 0.37 0.63 0.08
86 INT304456 Binding of P2rx1 and P2rx4 1 0.14 0 0.07
87 INT143120 Negative_regulation of VEGFB Positive_regulation of FLT1 1 0.36 0.58 0.07
88 INT300446 VEGFA Positive_regulation of Flt1 1 0.09 2.62 0.07
89 INT143121 VEGFB Positive_regulation of FLT1 1 0.42 0.58 0.07
90 INT241144 PGF Positive_regulation of FLT1 1 0.40 1.03 0.07
91 INT265750 Binding of FLT1 and KDR 1 0.37 0.54 0.07
92 INT158013 Binding of FLT1 and VEGFC 1 0.23 0.34 0.07
93 INT143119 Positive_regulation of VEGFB Positive_regulation of FLT1 1 0.30 0.58 0.07
94 INT320795 Flt1 Negative_regulation of VEGFA 1 0.29 0.29 0.06
95 INT183853 Gene_expression of CAV1 Negative_regulation of Positive_regulation of MAPK1 1 0.28 0.25 0.05
96 INT265764 NRP1 Positive_regulation of FLT1 1 0.45 0 0.04
97 INT241143 VEGFA Positive_regulation of FLT1 1 0.20 0.51 0.04
98 INT265745 FLT1 Positive_regulation of Binding of KLKB1 1 0.04 0.36 0.04
99 INT292080 Binding of FLT1 and TXK 1 0.04 1.47 0.04
100 INT292086 Negative_regulation of Binding of FLT1 and TXK 1 0.04 1.48 0.04
101 INT265749 Binding of FLT1 and NRP1 1 0.43 0 0.04
102 INT315914 VEGFA Regulation of FLT1 1 0.05 0.32 0.04
103 INT267093 FGFR1 Positive_regulation of Gene_expression of P2rx1 1 0.03 0.2 0.03
104 INT336765 Binding of FLT1 and ERAP2 1 0.30 0.58 0.03
105 INT220512 Cav1 Regulation of Positive_regulation of Cdkn1b 1 0.06 0.85 0.03
106 INT282799 Chrm2 Positive_regulation of Chrm3 1 0.16 0.29 0.03
107 INT312303 Positive_regulation of FLT1 Positive_regulation of VEGFA 1 0.38 0.73 0.03
108 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03
109 INT206705 Negative_regulation of Binding of FLT1 and VEGFA 3 0.11 1.9 0
110 INT300448 Binding of VEGFA and Flt1 3 0.10 1.93 0
111 INT329648 Flt1 Positive_regulation of Positive_regulation of VEGFA 1 0.03 0.58 0
112 INT351167 CAV1 Negative_regulation of Ppp2r1a 1 0.08 1.5 0
113 INT265753 Binding of FLT1 and KL 1 0.18 0 0
114 INT312330 Binding of Kdr and Flt1 1 0.12 0.37 0
115 INT300444 Flt1 Regulation of VEGFA 1 0.03 0.26 0
116 INT247660 PER1 Positive_regulation of TNNI3 1 0.01 0.35 0
117 INT288584 Cav1 Regulation of Gene_expression of Kcnma1 1 0.14 0 0
118 INT228117 Chrm2 Positive_regulation of Positive_regulation of Il10 1 0.22 0.61 0
119 INT288594 Regulation of Binding of CAV1 and Kcnma1 1 0.01 0 0
120 INT288588 Binding of Cav1 and Neu3 1 0.01 0 0
121 INT183895 CAV1 Regulation of Positive_regulation of Racgap1 1 0.01 0.37 0
122 INT265768 FLT1 Regulation of Binding of VEGFA 1 0.41 0 0
123 INT322246 Binding of Hcm and Tnni3 1 0.11 0.86 0
124 INT351166 Gtf3a Positive_regulation of Gene_expression of CAV1 1 0.01 0.79 0
125 INT265754 Binding of FLT1 and KLKB1 1 0.03 0.07 0
126 INT287072 Chrm2 Positive_regulation of Gene_expression of Irf4 1 0.18 0.06 0
127 INT351156 VEGFA Positive_regulation of Gene_expression of CAV1 1 0.07 0.79 0
128 INT265729 FLT1 Positive_regulation of Binding of VEGFA 1 0.46 0.08 0
129 INT287058 Chrm2 Regulation of Positive_regulation of Igis1 1 0.03 0.09 0
130 INT324663 Negative_regulation of Flt1 Positive_regulation of Vash1 1 0.44 0.55 0
131 INT265763 VEGFA Regulation of Binding of FLT1 1 0.41 0 0
132 INT280961 Binding of Cav1 and Cpox 1 0.04 0 0
133 INT287059 Gopc Positive_regulation of Positive_regulation of Chrm2 1 0.11 0.15 0
134 INT288587 Cav1 Regulation of Binding of Kcnma1 1 0.14 0 0
135 INT287077 Chrm2 Positive_regulation of Homer1 1 0.05 0.08 0
136 INT288597 Binding of CAV1 and Kcnma1 1 0.01 0.17 0
137 INT236528 Binding of Cav1 and Flna 1 0.06 0.09 0
138 INT265732 Positive_regulation of Binding of FLT1 and VEGFA 1 0.52 0 0
139 INT288596 Positive_regulation of Binding of CAV1 and Kcnma1 1 0.01 0.1 0
140 INT288590 Binding of Cav1 and Abhd14a 1 0.00 0 0
141 INT183857 CAV1 Positive_regulation of RHOC 1 0.46 0.21 0
142 INT351679 Fut1 Negative_regulation of Gene_expression of Flt1 1 0.00 1.01 0
143 INT300437 Kdr Regulation of Gene_expression of Flt1 1 0.42 0.26 0
144 INT228112 Gene_expression of Chrm2 Positive_regulation of Positive_regulation of Rac1 1 0.14 0.26 0
145 INT183861 Binding of CAV1 and CDC42EP5 1 0.03 3.21 0
146 INT288593 Cav1 Positive_regulation of Binding of Kcnma1 1 0.15 0 0
147 INT183864 Gene_expression of CAV1 Negative_regulation of Positive_regulation of RHOC 1 0.39 0.95 0
148 INT265752 NRP1 Negative_regulation of Gene_expression of FLT1 1 0.33 0 0
149 INT351165 Binding of CAV1 and Nos3 1 0.09 1.46 0
150 INT287076 Chrm2 Regulation of Irf4 1 0.10 0.09 0
151 INT351157 TSC1 Positive_regulation of Gene_expression of CAV1 1 0.01 1.43 0
152 INT300436 Flt1 Negative_regulation of Kdr 1 0.35 0.4 0
153 INT228109 Binding of Atm and Chrm2 1 0.09 0.21 0
154 INT287061 Chrm2 Positive_regulation of Phosphorylation of Vav1 1 0.14 0.15 0
155 INT183860 Binding of RHOC and CAV1 1 0.34 0.4 0
156 INT302927 Binding of Spna1 and Chrm2 1 0.00 0.35 0
157 INT265758 GOPC Positive_regulation of Gene_expression of FLT1 1 0.14 0 0
158 INT183856 Negative_regulation of RHOC Positive_regulation of Gene_expression of CAV1 1 0.42 0.09 0
159 INT183868 CAV1 Positive_regulation of PAF1 1 0.54 0.41 0
160 INT288591 Cav1 Positive_regulation of Kcnma1 1 0.15 0 0
161 INT262498 Binding of Aqp1 and Cav1 1 0.03 0.56 0
162 INT228115 Gene_expression of Chrm2 Positive_regulation of Phosphorylation of Vav1 1 0.16 0.26 0
163 INT298103 Binding of Cav1 and Ca2 1 0.03 0 0
164 INT351164 CAV1 Negative_regulation of Ppp1cc 1 0.11 1.5 0
165 INT265751 NRP1 Negative_regulation of Localization of FLT1 1 0.33 0 0
166 INT220518 Cav1 Negative_regulation of Akt1 1 0.04 1.02 0
167 INT228114 Chrm2 Positive_regulation of Gene_expression of Il10 1 0.22 0.61 0
168 INT287070 Gene_expression of Chrm2 Positive_regulation of Gene_expression of Il6 1 0.06 0.33 0
169 INT145556 Binding of CST3 and TNNI3 1 0.25 0.11 0
170 INT351158 CAV1 Regulation of SRC 1 0.01 0.68 0
171 INT287063 Chrm2 Positive_regulation of Gopc 1 0.10 0.06 0
172 INT265761 Binding of FLT1 and SRA1 1 0.01 0 0
173 INT312331 Binding of Flt1 and Pgf 1 0.08 0.31 0
174 INT80910 Binding of TNC and TNNI3 1 0.21 0.07 0
175 INT288592 Binding of Cav1 and Olfr1012 1 0.01 0 0
176 INT183866 CAV1 Regulation of RHOC 1 0.25 0.2 0
177 INT183867 Binding of CAV1 and Positive_regulation of Positive_regulation of RHOC 1 0.46 0.1 0
178 INT298104 Ca2 Negative_regulation of Cav1 1 0.04 0.09 0
179 INT315035 Binding of NAE1 and Cav1 1 0.01 0.7 0
180 INT247661 PER1 Positive_regulation of Positive_regulation of TNNI3 1 0.01 0.41 0
181 INT288586 Cav1 Positive_regulation of Regulation of Kcnma1 1 0.21 0 0
182 INT287066 Chrm2 Positive_regulation of Irf4 1 0.18 0.29 0
183 INT255691 Positive_regulation of Binding of VEGFA and Flt1 1 0.02 0 0
184 INT183852 CAV1 Regulation of Positive_regulation of RHOC 1 0.41 0.63 0
185 INT288558 Binding of CAV1 and KCNMA1 1 0.00 0 0
186 INT288583 Negative_regulation of Binding of Cav1 and Kcnma1 1 0.13 0 0
187 INT220526 Binding of Akt1 and Cav1 1 0.03 1.02 0
188 INT288589 Cav1 Regulation of Kcnma1 1 0.19 0.05 0
189 INT178723 Binding of ALB and TNNI3 1 0.17 0.91 0
190 INT351159 CAV1 Positive_regulation of AKT1 1 0.11 0.87 0
191 INT183854 Regulation of CAV1 Positive_regulation of RHOC 1 0.41 0.26 0
192 INT265774 Binding of FLT1 and GOPC 1 0.12 0 0
193 INT200558 Flt1 Regulation of Aliq1 1 0.02 0.97 0
194 INT265741 Negative_regulation of Binding of FLT1 and NRP1 1 0.38 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of smooth muscle contraction. They are ordered first by their pain relevance and then by number of times they were reported in regulation of smooth muscle contraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64436 Gene_expression of P2rx1 93 0.78 32.69 36.12
2 INT70776 Positive_regulation of P2rx1 62 0.62 32.55 30.75
3 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15
4 INT90942 Regulation of P2rx1 31 0.61 16.61 13.69
5 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
6 INT9550 Gene_expression of TNNI3 113 0.78 86.79 10.56
7 INT70775 Positive_regulation of Positive_regulation of P2rx1 15 0.49 8.65 8.49
8 INT95172 Localization of P2rx1 14 0.78 6.77 7.81
9 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41
10 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27
11 INT90943 Negative_regulation of P2rx1 13 0.42 8.21 7.22
12 INT114014 Positive_regulation of Gene_expression of P2rx1 13 0.69 7.77 7.15
13 INT91351 Gene_expression of P2rx1 28 0.75 5.89 6.78
14 INT16923 Positive_regulation of Tnni3 32 0.50 25.01 5.44
15 INT148402 Gene_expression of Chrm2 95 0.54 24.25 5.27
16 INT144396 Positive_regulation of P2rx1 11 0.49 3.25 4.23
17 INT100372 Gene_expression of Flt1 47 0.71 24.33 4.09
18 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
19 INT50872 Positive_regulation of Tnni3 24 0.64 13.51 3.95
20 INT95171 Binding of P2rx1 12 0.36 4.69 3.92
21 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
22 INT108728 Regulation of ATP1A2 4 0.45 3.65 3.04
23 INT186507 Localization of ATP1A2 2 0.74 3.35 3.04
24 INT26833 Negative_regulation of P2rx1 9 0.41 1.5 2.89
25 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
26 INT114011 Negative_regulation of ATP1A2 5 0.45 6.12 2.41
27 INT89146 Localization of Tnni3 7 0.51 4.31 2.38
28 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
29 INT9547 Regulation of TNNI3 25 0.56 14.22 2.22
30 INT121435 Negative_regulation of Gene_expression of P2rx1 3 0.43 1.82 2.21
31 INT148403 Positive_regulation of Chrm2 17 0.42 7.74 2.19
32 INT100371 Positive_regulation of Flt1 11 0.63 6.42 2.02
33 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
34 INT215166 Binding of P2rx1 5 0.35 0.41 1.97
35 INT143127 Positive_regulation of FLT1 44 0.66 21.7 1.92
36 INT64538 Binding of TNNI3 17 0.48 11.65 1.83
37 INT146948 Negative_regulation of Positive_regulation of P2rx1 2 0.34 2.23 1.74
38 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
39 INT85297 Positive_regulation of Gene_expression of TNNI3 29 0.50 29.77 1.68
40 INT103959 Gene_expression of ATP1A2 3 0.67 2.47 1.68
41 INT149435 Regulation of Positive_regulation of P2rx1 2 0.30 1.55 1.67
42 INT255663 Binding of Flt1 11 0.32 6.92 1.64
43 INT153530 Positive_regulation of NMS 4 0.39 4.17 1.63
44 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
45 INT63959 Regulation of Tnni3 11 0.21 4.69 1.57
46 INT77383 Gene_expression of Tnni3 8 0.65 4.14 1.55
47 INT151777 Regulation of Gene_expression of P2rx1 3 0.60 1.97 1.48
48 INT114013 Binding of ATP1A2 3 0.47 3.51 1.46
49 INT60552 Localization of TNNI3 56 0.79 20.05 1.44
50 INT118581 Positive_regulation of ATP1A2 3 0.21 1.81 1.4
51 INT199550 Negative_regulation of Flt1 18 0.37 12.57 1.37
52 INT100373 Negative_regulation of Gene_expression of Flt1 11 0.53 10 1.37
53 INT161182 Gene_expression of NMS 1 0.41 1.83 1.35
54 INT215162 Phosphorylation of P2rx1 2 0.43 0.12 1.34
55 INT75183 Negative_regulation of TNNI3 19 0.53 9.34 1.32
56 INT155662 Positive_regulation of Localization of P2rx1 2 0.47 1.92 1.26
57 INT65324 Gene_expression of Tnni3 12 0.66 7.97 1.25
58 INT141862 Binding of Cav1 11 0.36 1.32 1.25
59 INT50873 Regulation of Tnni3 4 0.13 2.36 1.22
60 INT132283 Regulation of P2rx1 3 0.13 0 1.2
61 INT31572 Negative_regulation of FLT1 21 0.48 16.49 1.18
62 INT160652 Positive_regulation of Binding of P2rx1 1 0.36 0.67 1.15
63 INT139764 Negative_regulation of CAV1 10 0.58 6.57 1.14
64 INT134627 Positive_regulation of Gene_expression of Flt1 9 0.49 7.16 1.12
65 INT76471 Negative_regulation of Tnni3 5 0.09 1.51 0.98
66 INT267071 Positive_regulation of Gene_expression of P2rx1 2 0.49 1.77 0.98
67 INT50878 Positive_regulation of Positive_regulation of TNNI3 7 0.50 5.57 0.97
68 INT136613 Negative_regulation of Cav1 2 0.57 2.28 0.96
69 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92
70 INT156351 Positive_regulation of Flt1 22 0.51 20.05 0.91
71 INT127103 Negative_regulation of Gene_expression of P2rx1 5 0.41 0.46 0.91
72 INT192123 Transcription of P2rx1 4 0.27 1.24 0.91
73 INT141442 Negative_regulation of Phosphorylation of Cav1 1 0.59 0.94 0.87
74 INT193042 Positive_regulation of Gene_expression of Chrm2 15 0.28 3.93 0.86
75 INT161775 Negative_regulation of Localization of Tnni3 1 0.23 0.85 0.86
76 INT141783 Binding of NMS 3 0.31 4.13 0.82
77 INT193060 Gene_expression of CHRM2 9 0.51 2.09 0.79
78 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78
79 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77
80 INT228105 Negative_regulation of Gene_expression of Chrm2 5 0.25 3.17 0.75
81 INT227949 Negative_regulation of Chrm2 8 0.25 4.23 0.73
82 INT68650 Negative_regulation of Tnni3 8 0.37 1.01 0.73
83 INT112088 Regulation of Cav1 2 0.44 0.51 0.73
84 INT153667 Localization of CAV1 15 0.76 11.92 0.68
85 INT161376 Protein_catabolism of TNNI3 7 1.00 3.92 0.67
86 INT85033 Positive_regulation of Chrna3 2 0.06 0.35 0.67
87 INT35926 Gene_expression of NMU 5 0.75 1.34 0.66
88 INT133004 Gene_expression of Chrna3 2 0.58 0.63 0.66
89 INT193037 Regulation of Chrm2 7 0.19 8.82 0.64
90 INT100374 Positive_regulation of Positive_regulation of Flt1 1 0.09 0.99 0.62
91 INT86700 Regulation of Cav1 7 0.54 0.92 0.61
92 INT131001 Regulation of CAV1 6 0.44 3.77 0.59
93 INT141863 Negative_regulation of Gene_expression of Cav1 4 0.49 1.77 0.58
94 INT287853 Phosphorylation of Tnni3 1 0.63 0.87 0.56
95 INT166757 Localization of NMS 2 0.65 1.69 0.55
96 INT215787 Localization of P2rx1 3 0.68 0.49 0.54
97 INT161181 Regulation of Gene_expression of NMS 1 0.28 1.09 0.53
98 INT143125 Binding of FLT1 48 0.40 13.6 0.51
99 INT255665 Localization of Flt1 5 0.63 7.65 0.51
100 INT109390 Regulation of Gene_expression of Flt1 4 0.41 4.08 0.51
101 INT86702 Localization of Cav1 8 0.69 0.76 0.47
102 INT65323 Positive_regulation of Positive_regulation of Tnni3 5 0.36 1.93 0.46
103 INT153672 Negative_regulation of Negative_regulation of CAV1 1 0.25 0.2 0.46
104 INT158019 Positive_regulation of Gene_expression of FLT1 20 0.68 9.73 0.44
105 INT136414 Regulation of NMU 2 0.26 1.28 0.44
106 INT220504 Positive_regulation of Gene_expression of Cav1 11 0.39 6.26 0.43
107 INT166240 Regulation of Gene_expression of Cav1 3 0.51 1.03 0.43
108 INT215494 Positive_regulation of Phosphorylation of P2rx1 1 0.26 0 0.42
109 INT190965 Positive_regulation of Gene_expression of NMS 1 0.09 0.41 0.41
110 INT193055 Positive_regulation of CHRM2 5 0.03 2.19 0.4
111 INT21932 Negative_regulation of NMS 2 0.37 1.96 0.4
112 INT255662 Regulation of Positive_regulation of Flt1 1 0.29 2.57 0.4
113 INT239115 Regulation of Binding of P2rx1 1 0.16 0 0.39
114 INT220506 Binding of Cav1 13 0.45 5.46 0.38
115 INT215503 Negative_regulation of Positive_regulation of P2rx1 1 0.23 0 0.38
116 INT135953 Negative_regulation of Positive_regulation of Cav1 2 0.37 1.09 0.37
117 INT133717 Positive_regulation of Gene_expression of Tnni3 1 0.11 0.54 0.36
118 INT341920 Negative_regulation of Binding of P2rx1 1 0.20 0.06 0.36
119 INT133718 Negative_regulation of Positive_regulation of Tnni3 1 0.09 0.38 0.36
120 INT163277 Negative_regulation of Gene_expression of CAV1 17 0.56 10.77 0.35
121 INT158967 Positive_regulation of Gene_expression of Tnni3 2 0.49 1.31 0.34
122 INT166759 Negative_regulation of Localization of NMS 2 0.37 0.87 0.31
123 INT166760 Regulation of Localization of NMS 2 0.39 0.87 0.31
124 INT354016 Positive_regulation of Positive_regulation of CHRM2 1 0.03 0.79 0.31
125 INT141867 Positive_regulation of Transcription of Cav1 2 0.52 0.46 0.29
126 INT141868 Transcription of Cav1 2 0.54 1.48 0.29
127 INT141861 Negative_regulation of Binding of Cav1 1 0.44 0.4 0.29
128 INT92313 Negative_regulation of Gene_expression of TNNI3 3 0.41 3.07 0.28
129 INT200550 Regulation of Flt1 7 0.45 5.22 0.27
130 INT36413 Regulation of NMS 2 0.23 1.97 0.27
131 INT81901 Binding of Tnni3 2 0.07 0.62 0.27
132 INT212762 Regulation of FLT1 21 0.58 2.95 0.26
133 INT35927 Positive_regulation of Gene_expression of NMU 2 0.67 0.17 0.26
134 INT238366 Positive_regulation of Positive_regulation of Chrm2 1 0.05 0.82 0.26
135 INT227952 Binding of Chrm2 9 0.19 5.19 0.25
136 INT236397 Binding of Flt1 5 0.33 1.91 0.24
137 INT135956 Phosphorylation of Cav1 5 0.64 2.24 0.22
138 INT135954 Positive_regulation of Phosphorylation of Cav1 2 0.40 0.64 0.22
139 INT141860 Regulation of Localization of Cav1 1 0.20 0.2 0.22
140 INT239841 Regulation of Protein_catabolism of TNNI3 1 0.32 1.6 0.2
141 INT324639 Transcription of Flt1 5 0.45 2.67 0.19
142 INT85574 Negative_regulation of Negative_regulation of Tnni3 1 0.29 0.1 0.19
143 INT228093 Regulation of Gene_expression of Chrm2 1 0.22 0.4 0.19
144 INT220497 Regulation of Gene_expression of Cav1 4 0.36 1.84 0.18
145 INT86697 Negative_regulation of Regulation of Cav1 1 0.41 0 0.18
146 INT50871 Positive_regulation of Positive_regulation of Tnni3 1 0.05 0.53 0.17
147 INT95662 Binding of Chrna3 1 0.00 0.17 0.17
148 INT131000 Positive_regulation of Positive_regulation of CAV1 1 0.49 0 0.17
149 INT158015 Regulation of Gene_expression of FLT1 10 0.52 1.66 0.16
150 INT204721 Localization of FLT1 30 0.73 4.64 0.15
151 INT145253 Negative_regulation of Cav1 9 0.46 3.02 0.15
152 INT227040 Negative_regulation of CHRM2 5 0.14 1.67 0.15
153 INT105044 Negative_regulation of Flt1 4 0.39 2.99 0.15
154 INT193072 Transcription of CHRM2 2 0.41 3.39 0.15
155 INT91650 Binding of Tnni3 2 0.36 0.73 0.15
156 INT90693 Transcription of TNNI3 2 0.55 1.56 0.15
157 INT103943 Regulation of Positive_regulation of TNNI3 1 0.25 0.4 0.15
158 INT163278 Regulation of Gene_expression of CAV1 5 0.45 4.36 0.14
159 INT236400 Regulation of Flt1 3 0.25 1.84 0.14
160 INT101021 Regulation of Positive_regulation of Tnni3 2 0.12 0.88 0.14
161 INT228087 Transcription of Chrm2 2 0.29 1.08 0.14
162 INT114012 Negative_regulation of Binding of ATP1A2 1 0.45 1.01 0.14
163 INT261639 Positive_regulation of CHRNA3 1 0.38 0.68 0.14
164 INT214975 Localization of Cav1 7 0.75 2.7 0.13
165 INT130572 Positive_regulation of Gene_expression of Flt1 2 0.46 3.24 0.13
166 INT238363 Positive_regulation of Transcription of Chrm2 1 0.05 1.05 0.13
167 INT193067 Positive_regulation of Transcription of CHRM2 1 0.03 1.03 0.13
168 INT340571 Positive_regulation of Localization of Flt1 1 0.10 0.88 0.13
169 INT287860 Regulation of Phosphorylation of Tnni3 1 0.21 0.16 0.12
170 INT228084 Localization of Chrm2 8 0.36 1.54 0.11
171 INT287850 Positive_regulation of Phosphorylation of Tnni3 1 0.54 0.09 0.11
172 INT341919 Positive_regulation of Binding of P2rx1 1 0.23 0 0.11
173 INT265803 Positive_regulation of Positive_regulation of FLT1 5 0.41 2.85 0.1
174 INT143126 Transcription of FLT1 1 0.38 0.72 0.1
175 INT353248 Negative_regulation of Positive_regulation of TNNI3 1 0.42 0.52 0.1
176 INT104815 Phosphorylation of FLT1 1 0.32 0.73 0.1
177 INT315145 Phosphorylation of Flt1 4 0.40 2.88 0.09
178 INT100628 Localization of Tnni3 1 0.18 0.73 0.09
179 INT261646 Localization of CHRNA3 1 0.65 0.91 0.09
180 INT86366 Phosphorylation of TNNI3 1 0.04 0.51 0.09
181 INT220491 Transcription of Cav1 2 0.54 1.1 0.07
182 INT72267 Positive_regulation of Regulation of TNNI3 1 0.44 0.4 0.07
183 INT220500 Positive_regulation of Transcription of Cav1 1 0.16 0.9 0.07
184 INT193058 Negative_regulation of Gene_expression of CHRM2 2 0.28 1.01 0.06
185 INT292803 Negative_regulation of Phosphorylation of Flt1 1 0.10 0.46 0.06
186 INT292801 Phosphorylation of Flt1 1 0.19 0.46 0.06
187 INT247662 Positive_regulation of Localization of TNNI3 7 0.68 2.51 0.05
188 INT227041 Localization of CHRM2 2 0.49 0.34 0.05
189 INT220502 Positive_regulation of Positive_regulation of Cav1 1 0.24 0.21 0.05
190 INT282797 Negative_regulation of Binding of Chrm2 1 0.19 0 0.05
191 INT315009 Regulation of Phosphorylation of Cav1 1 0.36 0.2 0.05
192 INT207668 Binding of Chrnb4 1 0.27 0 0.05
193 INT227039 Binding of CHRM2 1 0.01 0.24 0.05
194 INT255664 Regulation of Gene_expression of Flt1 2 0.44 1.67 0.04
195 INT300713 Regulation of Localization of Cav1 2 0.42 1.37 0.04
196 INT215817 Transcription of P2rx1 1 0.18 0 0.04
197 INT314252 Transcription of CAV1 1 0.50 0.07 0.04
198 INT200553 Negative_regulation of Gene_expression of Flt1 11 0.33 6.79 0.03
199 INT183878 Negative_regulation of Positive_regulation of CAV1 1 0.41 0.16 0.03
200 INT321430 Positive_regulation of Binding of FLT1 1 0.20 1 0.03
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