GO:0006944

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Name cellular membrane fusion
Categary Process
Go Slim No
Go Link GO:0006944
Unique Molecular Interactions 45
Total Molecular Interactions 60
Total Single Events 141
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular membrane fusion. They are ordered first by their pain relevance and then by number of times they were reported for cellular membrane fusion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT127585 Binding of CNR2 and Ctbp1 1 0.00 0.6 0.76
2 INT23681 Negative_regulation of Binding of Stx3 and Chrna7 1 0.00 0 0.75
3 INT23680 Binding of Stx3 and Chrna7 1 0.00 0 0.75
4 INT127584 Binding of CNR1 and Ctbp1 1 0.00 0.6 0.75
5 INT113610 Binding of Nsf and Grip2 1 0.24 0.6 0.63
6 INT37034 PLAT Positive_regulation of PLDN 1 0.08 0.15 0.58
7 INT23679 Chrna7 Regulation of Binding of Stx3 1 0.00 0 0.56
8 INT328184 Positive_regulation of Slc3a1 Positive_regulation of Nsf 1 0.00 0.15 0.43
9 INT328183 Slc3a1 Positive_regulation of Nsf 1 0.00 0.15 0.43
10 INT255292 Regulation of Binding of Napb and Vamp2 1 0.07 0 0.3
11 INT255286 Binding of Napb and Vamp2 1 0.09 0 0.29
12 INT255284 Binding of Vamp2 and Vti1b 1 0.16 0 0.29
13 INT37033 PLAT Negative_regulation of PLDN 1 0.08 0.07 0.23
14 INT287764 Binding of Gria2 and Nsf 1 0.34 0.33 0.18
15 INT118127 Binding of STXBP3 and Stx4 1 0.01 0.24 0.15
16 INT118126 Binding of STXBP3 and Snap23 1 0.18 0.24 0.15
17 INT149541 Binding of GCA and TADA1 1 0.40 1.4 0.13
18 INT214952 Vamp2 Regulation of Rims1 1 0.17 0 0.12
19 INT214955 Binding of Syt1 and Vamp2 1 0.22 0 0.1
20 INT214957 Vamp2 Regulation of Neu3 1 0.00 0 0.1
21 INT249413 Binding of Vamp2 and Napa 1 0.15 0.05 0.09
22 INT118121 Binding of VTI1B and UNC13B 1 0.00 0.14 0.07
23 INT263761 Grin1 Regulation of Localization of Vamp2 1 0.27 0.17 0.07
24 INT263777 Grin2a Regulation of Localization of Vamp2 1 0.26 0.17 0.07
25 INT263734 Dlg4 Regulation of Localization of Vamp2 1 0.15 0.17 0.07
26 INT263739 Grin2b Regulation of Localization of Vamp2 1 0.24 0.17 0.07
27 INT263735 Localization of Neto1 Regulation of Localization of Vamp2 1 0.35 0.18 0.05
28 INT249421 Binding of Stx1a and Vamp2 1 0.10 0 0.04
29 INT249404 Binding of Snap25 and Vamp2 1 0.16 0 0.04
30 INT330875 PLDN Negative_regulation of Gene_expression of Ache 1 0.01 0.85 0.03
31 INT298858 Positive_regulation of Binding of VAPA and RILP 1 0.07 0.54 0
32 INT283341 Binding of Ctbp1 and Fig4 1 0.06 0 0
33 INT312043 NAPA Regulation of TNF 1 0.26 0 0
34 INT198144 Binding of PLDN and ANTXR2 1 0.00 3.4 0
35 INT298845 VAPA Regulation of Negative_regulation of RAB7A 1 0.12 0.32 0
36 INT330876 PLDN Negative_regulation of Ache 1 0.01 0.45 0
37 INT249410 Vamp2 Regulation of Binding of Stx1a 1 0.06 0 0
38 INT198184 Binding of PLDN and Antxr1 1 0.00 1.03 0
39 INT330877 PLDN Positive_regulation of Gins4 1 0.00 0.08 0
40 INT198183 Binding of PLDN and Gtf3a 1 0.00 0.81 0
41 INT312044 NAPA Negative_regulation of Phosphorylation of HIST2H3C 1 0.08 0 0
42 INT249407 Mbp Positive_regulation of Localization of Vamp2 1 0.13 0.11 0
43 INT283347 Binding of Srr and Ctbp1 1 0.13 0 0
44 INT249422 Binding of Mbp and Vamp2 1 0.12 0 0
45 INT298847 Binding of VAPA and RILP 1 0.05 0.54 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular membrane fusion. They are ordered first by their pain relevance and then by number of times they were reported in cellular membrane fusion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT125996 Gene_expression of Nsf 7 0.75 1.73 5.3
2 INT132271 Positive_regulation of Gene_expression of Nsf 1 0.45 0.51 2.46
3 INT346375 Protein_catabolism of Vamp2 1 0.33 1.56 2.46
4 INT249378 Negative_regulation of Vamp2 3 0.20 0.27 2.4
5 INT132270 Regulation of Gene_expression of Nsf 1 0.44 0.46 2.3
6 INT113608 Positive_regulation of Nsf 2 0.39 1.03 2.22
7 INT23668 Binding of Stx3 1 0.01 0 1.31
8 INT13263 Binding of Ctbp1 2 0.41 0.57 1.06
9 INT249383 Binding of Vamp2 5 0.23 0.33 1.03
10 INT234081 Gene_expression of Vamp2 9 0.51 0.71 0.94
11 INT249377 Localization of Vamp2 4 0.51 0.4 0.93
12 INT132269 Transcription of Nsf 1 0.45 0.19 0.89
13 INT132268 Positive_regulation of Transcription of Nsf 1 0.39 0.19 0.89
14 INT201251 Negative_regulation of NAPA 2 0.30 0 0.88
15 INT125989 Negative_regulation of Gene_expression of Nsf 1 0.41 0.06 0.79
16 INT23671 Negative_regulation of Stx3 1 0.01 0 0.75
17 INT201257 Positive_regulation of VAPA 1 0.01 0 0.71
18 INT11358 Gene_expression of PLDN 2 0.11 1.16 0.55
19 INT346370 Regulation of Localization of Vamp2 1 0.15 0.08 0.53
20 INT346393 Regulation of Protein_catabolism of Vamp2 1 0.09 0.08 0.53
21 INT336690 Negative_regulation of Gene_expression of Vamp2 2 0.16 0.28 0.46
22 INT328192 Positive_regulation of Positive_regulation of Nsf 1 0.05 0.15 0.43
23 INT37038 Positive_regulation of PLDN 1 0.10 0.07 0.34
24 INT37039 Regulation of PLDN 2 0.05 0.95 0.32
25 INT334791 Binding of Nsf 1 0.12 0.39 0.26
26 INT76584 Gene_expression of GCA 1 0.58 1.29 0.24
27 INT79719 Negative_regulation of VAPA 6 0.43 2.94 0.21
28 INT13262 Regulation of Ctbp1 1 0.01 0.25 0.18
29 INT328187 Regulation of Nsf 1 0.04 0 0.18
30 INT76278 Binding of VAPA 4 0.48 3.32 0.16
31 INT149542 Binding of GCA 1 0.47 1.4 0.13
32 INT346395 Positive_regulation of Protein_catabolism of Vamp2 1 0.16 0.13 0.13
33 INT249379 Positive_regulation of Vamp2 3 0.33 0 0.08
34 INT312058 Localization of NAPA 1 0.54 0.29 0.08
35 INT118125 Binding of VTI1B 1 0.01 0.14 0.07
36 INT234092 Regulation of Vamp2 2 0.20 0.17 0.05
37 INT16799 Positive_regulation of Phosphorylation of Ctbp1 1 0.10 0 0.05
38 INT16801 Phosphorylation of Ctbp1 1 0.16 0 0.05
39 INT312052 Positive_regulation of Localization of NAPA 1 0.31 0.14 0.04
40 INT312053 Negative_regulation of Localization of NAPA 1 0.27 0.14 0.04
41 INT312060 Binding of NAPA 1 0.27 0.11 0.03
42 INT330874 Negative_regulation of PLDN 1 0.01 0.15 0.03
43 INT283318 Localization of Ctbp1 1 0.54 0 0.03
44 INT336691 Regulation of Gene_expression of Vamp2 1 0.19 0.43 0.03
45 INT312054 Phosphorylation of NAPA 1 0.39 0 0
46 INT312066 Regulation of Gene_expression of NAPA 1 0.28 0 0
47 INT312067 Gene_expression of NAPA 1 0.48 0 0
48 INT283324 Gene_expression of Ctbp1 1 0.18 0 0
49 INT198182 Binding of PLDN 1 0.00 5.49 0
50 INT249397 Negative_regulation of Binding of Vamp2 1 0.28 0 0
51 INT198180 Regulation of Binding of PLDN 1 0.00 0.23 0
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