GO:0006952

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Name defense response
Categary Process
Go Slim No
Go Link GO:0006952
Unique Molecular Interactions 779
Total Molecular Interactions 1066
Total Single Events 9856
Pain Genes Associated 61

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for defense response. They are ordered first by their pain relevance and then by number of times they were reported for defense response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
2 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
3 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
4 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
5 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
6 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
7 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
8 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
9 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
10 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
11 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
12 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
13 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
14 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
15 INT14991 SFTPA1 Positive_regulation of Localization of MPO 1 0.11 1.65 1.92
16 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
17 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73
18 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
19 INT157459 Binding of CX3CR1 and CX3CL1 1 0.32 2.12 1.7
20 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
21 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
22 INT174503 Binding of HLA-B and KIR3DL1 6 0.37 3.48 1.61
23 INT107965 Binding of HLA-B and Mefv 2 0.34 3.91 1.61
24 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
25 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
26 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
27 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
28 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
29 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
30 INT55837 Binding of HLA-B and PHB2 3 0.20 3.52 1.37
31 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
32 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
33 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
34 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
35 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27
36 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
37 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
38 INT212815 WAS Positive_regulation of CNR1 1 0.01 0.62 1.16
39 INT212824 WAS Positive_regulation of Cnr1 1 0.21 0.62 1.16
40 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
41 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1
42 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
43 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
44 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
45 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
46 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
47 INT176474 Binding of CXCR3 and CXCL9 3 0.22 1.9 1.05
48 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
49 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
50 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
51 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
52 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03
53 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
54 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
55 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
56 INT41659 IL31RA Regulation of PRL 1 0.22 1.07 0.98
57 INT41658 IL31RA Regulation of GH1 1 0.09 1.07 0.98
58 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
59 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
60 INT275406 Binding of ITIH4 and Ccr5 1 0.09 2.88 0.97
61 INT275390 Binding of Ccr5 and Htatsf1 1 0.01 3.26 0.97
62 INT256357 Phosphorylation of Rela Positive_regulation of Localization of Ik 1 0.00 0.05 0.96
63 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
64 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
65 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
66 INT143323 Binding of HLA-B and HP 1 0.04 0.95 0.93
67 INT34271 Positive_regulation of WAS Positive_regulation of Oprd1 1 0.01 0 0.91
68 INT34273 WAS Regulation of Oprd1 1 0.00 0 0.91
69 INT34272 WAS Positive_regulation of Oprd1 1 0.01 0 0.91
70 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
71 INT247759 Binding of Ccrl2 and Rarres2 1 0.26 1.19 0.9
72 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
73 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89
74 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
75 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
76 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
77 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88
78 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
79 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
80 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
81 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
82 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
83 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
84 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
85 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
86 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86
87 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86
88 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
89 INT150733 Negative_regulation of Tlr3 Negative_regulation of Positive_regulation of Il1b 1 0.48 1.34 0.83
90 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
91 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
92 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
93 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
94 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
95 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
96 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
97 INT289658 Tnfrsf1a Positive_regulation of Mcpt1 1 0.02 0.76 0.81
98 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
99 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
100 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 1 0.46 0.48 0.77
101 INT224463 TPSAB1 Positive_regulation of F2RL1 2 0.03 1.49 0.76
102 INT250959 Binding of HLA-B and SOD1 1 0.05 0.75 0.75
103 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75
104 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 0.31 1.21 0.74
105 INT96301 Olr1742 Negative_regulation of Gene_expression of Tnf 1 0.14 0 0.74
106 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72
107 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72
108 INT275285 Ros1 Positive_regulation of Tnfrsf1a 1 0.27 1.06 0.72
109 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
110 INT82767 Binding of HP and MLRG 1 0.00 0 0.71
111 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
112 INT28711 Binding of HLA-B and MRAP 2 0.23 0.96 0.69
113 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 0.15 1.08 0.69
114 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69
115 INT155457 Tnfrsf1a Positive_regulation of Mapk14 1 0.20 1.17 0.67
116 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
117 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
118 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
119 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
120 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
121 INT120146 seb Positive_regulation of Gene_expression of Tnf 1 0.40 0.86 0.66
122 INT120145 seb Positive_regulation of Tnf 1 0.40 0.85 0.65
123 INT132689 Tnf Regulation of Dnajc13 1 0.01 1.27 0.65
124 INT18231 Binding of ADRA1D and HP 2 0.14 0.17 0.64
125 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
126 INT165048 Trib3 Positive_regulation of Gene_expression of Tnf 1 0.08 0.8 0.63
127 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
128 INT174500 Positive_regulation of Binding of CD4 and HLA-B 1 0.21 2.33 0.63
129 INT155458 Tnfrsf1a Regulation of Gene_expression of Il6 1 0.22 1.11 0.63
130 INT121713 WAS Positive_regulation of Gene_expression of SELP 1 0.30 0.49 0.63
131 INT60328 Il1b Positive_regulation of Tnf 2 0.29 1.84 0.62
132 INT9163 Tnf Regulation of Gene_expression of Glul 1 0.12 1.99 0.62
133 INT61826 Tnf Negative_regulation of Il1b 1 0.39 0.89 0.62
134 INT158362 Tnf Positive_regulation of Steap4 1 0.55 1.6 0.61
135 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61
136 INT122096 Binding of HLA-B and SFTPA1 2 0.04 1.81 0.6
137 INT174504 Binding of HLA-B and KIR3DL2 2 0.24 1.69 0.59
138 INT96241 Il13 Negative_regulation of Tnf 1 0.08 0.6 0.59
139 INT87683 Binding of HLA-B and Prnd 1 0.00 0.59 0.59
140 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
141 INT61827 Tnf Regulation of Lta 1 0.40 1.5 0.58
142 INT26648 Binding of CEL and HP 1 0.04 0 0.58
143 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
144 INT94506 Tnf Positive_regulation of Gene_expression of Avp 1 0.31 0.98 0.57
145 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57
146 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
147 INT94507 Tnf Positive_regulation of Gene_expression of AVP 1 0.39 0.98 0.57
148 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
149 INT8402 Tnf Regulation of Gene_expression of Vip 1 0.02 0.38 0.56
150 INT8400 Tnf Regulation of Gene_expression of Nts 1 0.00 0.38 0.56
151 INT148922 Pdia4 Negative_regulation of Tnf 1 0.09 1.01 0.56
152 INT146112 Binding of Il1b and Tnf 1 0.32 1.19 0.56
153 INT183695 Binding of Tlr3 and Ducm1 1 0.04 2.75 0.56
154 INT94499 Tnf Positive_regulation of Gene_expression of Crh 1 0.27 0.97 0.56
155 INT244232 Binding of Ccr5 and Ccl4 3 0.17 1.48 0.55
156 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55
157 INT131316 Tnf Positive_regulation of Mpo 1 0.29 0.65 0.55
158 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55
159 INT220051 Fcgr4 Positive_regulation of Gene_expression of Ido1 1 0.01 1.24 0.55
160 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
161 INT267707 Binding of Tnf and ARID1B 2 0.20 8.2 0.54
162 INT137162 IFNG Positive_regulation of Gene_expression of CXCL9 1 0.45 0.62 0.54
163 INT352268 Tnf Positive_regulation of Arl6ip6 1 0.02 2.42 0.54
164 INT137157 TNF Positive_regulation of Gene_expression of CXCL9 1 0.38 0.61 0.54
165 INT8397 Tnf Regulation of Nts 1 0.00 0.38 0.53
166 INT8398 Tnf Regulation of Vip 1 0.01 0.38 0.53
167 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52
168 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52
169 INT346205 Binding of CD74 and TPPP 1 0.02 0.87 0.51
170 INT206960 Lipg Regulation of Tnf 1 0.02 0.85 0.51
171 INT117309 HP Positive_regulation of Gast 1 0.00 0.9 0.51
172 INT271344 MPO Regulation of Protein_catabolism of ACCS 1 0.02 2.42 0.51
173 INT23090 Tnf Positive_regulation of Localization of Prl 1 0.18 0.15 0.5
174 INT23091 Tnf Positive_regulation of Localization of Ggh 1 0.05 0.15 0.5
175 INT23092 Tnf Positive_regulation of Prl 1 0.08 0.15 0.5
176 INT93740 Ddc Positive_regulation of Tnf 1 0.00 1.45 0.5
177 INT23089 Tnf Positive_regulation of Ggh 1 0.04 0.15 0.5
178 INT14992 FPR1 Positive_regulation of Localization of MPO 2 0.56 1.1 0.49
179 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
180 INT285344 Il10 Negative_regulation of Gene_expression of Tnf 1 0.15 1.91 0.49
181 INT102214 ENG Negative_regulation of HP 1 0.01 0 0.49
182 INT161227 Binding of Ngfr and Tnf 1 0.06 0.41 0.49
183 INT36143 Binding of SERPINH1 and HLA-B 1 0.00 0.66 0.49
184 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
185 INT118485 CST3 Regulation of CTSH 1 0.36 0 0.49
186 INT348173 Binding of HLA-B and IL23R 1 0.15 0.92 0.49
187 INT155621 Tnf Regulation of Transcription of Il1b 1 0.51 0.77 0.49
188 INT275286 Ros1 Regulation of Positive_regulation of Tnfrsf1a 1 0.16 0.55 0.49
189 INT348177 Binding of HLA-B and ERAP1 1 0.14 0.92 0.49
190 INT187796 Binding of Tnf and Il1 1 0.09 1.85 0.48
191 INT67440 Pdyn Regulation of Gene_expression of Tnf 1 0.23 0.19 0.48
192 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
193 INT158599 Tlr3 Positive_regulation of Binding of Fas 1 0.55 0.86 0.48
194 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
195 INT328936 Binding of HLA-B and KIR3DS1 1 0.25 0.7 0.48
196 INT187795 Positive_regulation of Binding of Tnf and Il1 1 0.13 1.87 0.48
197 INT137416 Binding of SDC1 and Tnf 1 0.00 1.19 0.47
198 INT340440 Binding of HLA-B and BTG3 1 0.05 1.57 0.47
199 INT102213 Binding of ENG and HP 1 0.01 0 0.47
200 INT252634 Binding of TNF and Tnfrsf1a 4 0.02 2.4 0.46

Single Events

The table below shows the top 100 pain related interactions that have been reported for defense response. They are ordered first by their pain relevance and then by number of times they were reported in defense response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
2 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
3 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
4 INT1878 Binding of HLA-B 440 0.48 321.16 127.36
5 INT10166 Localization of Tnf 237 0.81 153.95 88.64
6 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37
7 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
8 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
9 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
10 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
11 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
12 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
13 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
14 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
15 INT35406 Localization of Tnf 94 0.81 64.63 31.65
16 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
17 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
18 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2
19 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03
20 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09
21 INT12114 Positive_regulation of Tnfrsf1a 46 0.69 36.26 22.54
22 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
23 INT1876 Positive_regulation of HLA-B 82 0.69 52.16 21.08
24 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
25 INT157463 Gene_expression of CX3CL1 55 0.62 69.05 19.75
26 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
27 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
28 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
29 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
30 INT167679 Gene_expression of Ccr5 74 0.75 59.03 18.16
31 INT101140 Negative_regulation of Tap1 7 0.50 9.08 17.46
32 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89
33 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
34 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
35 INT170308 Gene_expression of Ido1 159 0.75 69.51 15.98
36 INT93482 Localization of Rela 56 0.78 24.52 14.82
37 INT5904 Localization of MPO 62 0.81 36.37 14.64
38 INT10173 Binding of Tnf 45 0.48 35.6 14.32
39 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
40 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2
41 INT8548 Gene_expression of HP 86 0.77 47.62 11.94
42 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9
43 INT87698 Gene_expression of WAS 25 0.58 8.75 11.83
44 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
45 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
46 INT4806 Localization of TPSAB1 29 0.80 5.05 10.52
47 INT87393 Gene_expression of Ccr5 19 0.65 11 10.51
48 INT137181 Gene_expression of CXCL9 25 0.65 13.09 9.56
49 INT3925 Negative_regulation of HLA-B 29 0.42 20.19 9.46
50 INT71494 Positive_regulation of Hspa1b 14 0.67 8.5 9.19
51 INT141502 Positive_regulation of CX3CL1 21 0.55 25.8 8.88
52 INT157467 Positive_regulation of Gene_expression of CX3CL1 6 0.55 16.67 8.84
53 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
54 INT34268 Binding of WAS 14 0.47 4.41 8.67
55 INT3353 Localization of HLA-B 25 0.75 16.05 8.62
56 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
57 INT77790 Positive_regulation of Gene_expression of Tnfrsf1a 16 0.67 15.88 8.5
58 INT56223 Positive_regulation of MPO 35 0.70 43 8.2
59 INT166748 Gene_expression of IL32 2 0.58 38.6 8.14
60 INT87699 Positive_regulation of WAS 16 0.45 5.84 8.03
61 INT14043 Binding of HP 52 0.30 26.56 7.76
62 INT5284 Regulation of HLA-B 25 0.59 12.91 7.74
63 INT170295 Positive_regulation of Ido1 40 0.67 28.89 7.61
64 INT68299 Binding of Tnf 17 0.39 12.55 7.49
65 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36
66 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
67 INT33105 Regulation of WAS 11 0.60 3.61 7.18
68 INT153268 Positive_regulation of Ccr5 25 0.66 19 7.02
69 INT16722 Negative_regulation of MPO 25 0.59 18.55 6.99
70 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
71 INT256345 Phosphorylation of Rela 21 0.75 9.51 6.56
72 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47
73 INT275265 Negative_regulation of Positive_regulation of Tnfrsf1a 1 0.56 4.41 6.35
74 INT170315 Positive_regulation of Gene_expression of Ido1 50 0.67 25.39 6.06
75 INT73179 Gene_expression of Hspa1b 10 0.73 6.24 6.04
76 INT677 Positive_regulation of CST3 20 0.67 17.47 6
77 INT4697 Positive_regulation of Gene_expression of HLA-B 32 0.61 17.32 5.97
78 INT275272 Positive_regulation of Positive_regulation of Tnfrsf1a 8 0.48 6.44 5.97
79 INT120089 Negative_regulation of Ccr5 7 0.58 10.36 5.91
80 INT63177 Regulation of HP 71 0.44 39.48 5.86
81 INT94118 Localization of Tnfrsf1a 9 0.72 7.24 5.81
82 INT103847 Positive_regulation of Ccr5 11 0.55 6.04 5.79
83 INT181406 Binding of Ccr5 16 0.45 17 5.78
84 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
85 INT105538 Negative_regulation of Tnfrsf1a 16 0.56 12.51 5.61
86 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
87 INT5903 Negative_regulation of Localization of MPO 10 0.59 5.71 5.45
88 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
89 INT111520 Regulation of Tnfrsf1a 10 0.61 7.25 5.41
90 INT4805 Positive_regulation of Localization of TPSAB1 9 0.55 0.32 5.38
91 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
92 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16
93 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
94 INT137179 Positive_regulation of CXCL9 11 0.65 7.73 5.11
95 INT174193 Gene_expression of LILRA3 20 0.28 12.65 5.1
96 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
97 INT170311 Negative_regulation of Ido1 16 0.48 14.47 4.81
98 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75
99 INT183681 Positive_regulation of Tlr3 20 0.62 16.25 4.54
100 INT170988 Positive_regulation of CYSLTR1 15 0.34 6.23 4.44
101 INT93739 Positive_regulation of Gene_expression of Tnfrsf1a 11 0.66 11.17 4.44
102 INT118230 Binding of Tnfrsf1a 15 0.42 7.63 4.39
103 INT187836 Binding of Tnfrsf1a 19 0.46 18.08 4.33
104 INT93483 Negative_regulation of Localization of Rela 11 0.57 5.1 4.19
105 INT158377 Positive_regulation of Positive_regulation of Rela 6 0.49 3.08 4.11
106 INT253970 Positive_regulation of Cd74 3 0.48 8.16 4.09
107 INT158595 Gene_expression of Tlr3 25 0.69 12.09 4.07
108 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
109 INT48456 Localization of WAS 6 0.56 1.63 3.95
110 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
111 INT97139 Gene_expression of CD83 43 0.70 22.05 3.91
112 INT103843 Positive_regulation of Gene_expression of Ccr5 5 0.42 2.31 3.89
113 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
114 INT133550 Negative_regulation of Gene_expression of Rela 14 0.40 4.64 3.73
115 INT158596 Binding of Tlr3 24 0.47 11.66 3.69
116 INT77786 Negative_regulation of Tnfrsf1a 5 0.56 5.03 3.58
117 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57
118 INT195527 Binding of Rela 17 0.25 4.42 3.56
119 INT77788 Regulation of Tnfrsf1a 14 0.57 11.24 3.53
120 INT187168 Binding of Cd74 13 0.27 11.2 3.44
121 INT96700 Positive_regulation of Positive_regulation of Tnfrsf1a 6 0.69 3.93 3.42
122 INT14994 Positive_regulation of Localization of MPO 12 0.70 6.85 3.37
123 INT24983 Binding of MPO 18 0.42 17.56 3.29
124 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
125 INT133557 Transcription of Rela 6 0.52 3.86 3.2
126 INT105297 Negative_regulation of Regulation of WAS 3 0.28 0.98 3.07
127 INT141180 Gene_expression of Apaf1 6 0.74 5.77 2.98
128 INT166879 Localization of Ccr5 4 0.71 3.62 2.97
129 INT16959 Positive_regulation of Binding of HLA-B 8 0.50 6.77 2.96
130 INT2249 Negative_regulation of Binding of HLA-B 5 0.54 6.82 2.94
131 INT120827 Regulation of CX3CL1 3 0.14 2.24 2.94
132 INT103910 Binding of NOD2 19 0.47 12.24 2.93
133 INT133080 Gene_expression of GATA3 15 0.61 5.64 2.89
134 INT13634 Gene_expression of CYSLTR1 19 0.75 11.24 2.88
135 INT167039 Gene_expression of Cd74 24 0.40 17.12 2.84
136 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
137 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
138 INT153221 Positive_regulation of Rela 5 0.16 2.16 2.72
139 INT73175 Positive_regulation of Gene_expression of Hspa1b 3 0.48 2.53 2.72
140 INT243350 Binding of CD74 2 0.11 4.86 2.72
141 INT162792 Gene_expression of NOD1 19 0.71 6.11 2.71
142 INT75736 Regulation of Localization of Tnf 6 0.62 4.61 2.67
143 INT96273 Binding of TAP1 4 0.37 4.27 2.67
144 INT87395 Binding of Ccr5 5 0.29 2.5 2.6
145 INT193251 Binding of CYSLTR1 13 0.32 8.32 2.57
146 INT19134 Gene_expression of TPSAB1 16 0.66 11.61 2.48
147 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
148 INT141195 Negative_regulation of Rela 14 0.29 8.61 2.44
149 INT162518 Positive_regulation of Localization of Rela 12 0.47 1.96 2.41
150 INT229063 Positive_regulation of Gene_expression of IL32 1 0.52 16.13 2.37
151 INT166745 Positive_regulation of IL32 2 0.52 13.52 2.35
152 INT170323 Regulation of Gene_expression of Ido1 11 0.60 8.74 2.33
153 INT229074 Regulation of Gene_expression of IL32 1 0.46 10.18 2.29
154 INT10612 Localization of NLRP3 13 0.78 8.91 2.27
155 INT640 Regulation of CST3 9 0.60 4.04 2.26
156 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
157 INT181356 Positive_regulation of Gene_expression of Ccr5 11 0.66 8.3 2.24
158 INT33243 Localization of HP 17 0.12 9.7 2.2
159 INT275279 Positive_regulation of Localization of Tnfrsf1a 3 0.48 1.13 2.17
160 INT96743 Transcription of Ccr5 2 0.54 2.72 2.17
161 INT228707 Positive_regulation of Gene_expression of MPO 10 0.57 17.85 2.1
162 INT178799 Positive_regulation of Camp 8 0.43 4.37 2.1
163 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
164 INT24453 Binding of NLRP3 18 0.48 13.7 1.93
165 INT130392 Positive_regulation of Gene_expression of HP 7 0.69 7.34 1.9
166 INT209890 Positive_regulation of Gene_expression of CD83 11 0.62 9.04 1.88
167 INT253975 Binding of Cd74 4 0.27 4.57 1.88
168 INT284521 Negative_regulation of CX3CL1 11 0.27 13.86 1.87
169 INT144649 Negative_regulation of Positive_regulation of Rela 11 0.26 8.27 1.87
170 INT14500 Positive_regulation of Gene_expression of CST3 9 0.67 7.46 1.87
171 INT141191 Positive_regulation of Gene_expression of Apaf1 1 0.48 2.33 1.85
172 INT56221 Regulation of MPO 8 0.61 8.44 1.84
173 INT78665 Gene_expression of Irgm1 12 0.65 3.17 1.83
174 INT117221 Positive_regulation of Gene_expression of NOD2 7 0.65 4.39 1.83
175 INT183381 Transcription of Tnfrsf1a 3 0.46 2.08 1.83
176 INT8787 Negative_regulation of WAS 4 0.42 2.42 1.81
177 INT41660 Regulation of IL31RA 2 0.45 1.46 1.81
178 INT162793 Regulation of NOD2 6 0.45 7.61 1.78
179 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
180 INT87394 Negative_regulation of Ccr5 3 0.32 1.3 1.74
181 INT122951 Regulation of Binding of HLA-B 4 0.39 3.08 1.65
182 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
183 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
184 INT256341 Positive_regulation of Phosphorylation of Rela 5 0.46 2.12 1.62
185 INT97133 Positive_regulation of CD83 3 0.42 11.97 1.61
186 INT60975 Localization of CST3 6 0.78 2.4 1.58
187 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
188 INT23171 Negative_regulation of NLRP3 7 0.37 4.15 1.53
189 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
190 INT14477 Positive_regulation of TPSAB1 10 0.69 5.88 1.46
191 INT66792 Binding of TPSAB1 7 0.16 4.93 1.45
192 INT83659 Negative_regulation of Binding of Tnf 3 0.37 1.57 1.42
193 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
194 INT165493 Binding of CX3CL1 5 0.21 3.08 1.41
195 INT271443 Regulation of Cd74 1 0.33 2.73 1.4
196 INT23986 Positive_regulation of Ifnb1 4 0.42 0.62 1.39
197 INT107924 Localization of Tnfrsf1a 5 0.70 3.86 1.37
198 INT150730 Regulation of Tlr3 2 0.45 6.51 1.37
199 INT77785 Negative_regulation of Gene_expression of Tnfrsf1a 4 0.56 3.1 1.35
200 INT133552 Negative_regulation of Transcription of Rela 2 0.23 2.43 1.34
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