GO:0006954

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Name inflammatory response
Categary Process
Go Slim No
Go Link GO:0006954
Unique Molecular Interactions 10182
Total Molecular Interactions 14962
Total Single Events 123913
Pain Genes Associated 380

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for inflammatory response. They are ordered first by their pain relevance and then by number of times they were reported for inflammatory response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
3 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
4 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
5 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
6 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
7 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
8 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
9 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
10 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
11 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87
12 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
13 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
14 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
15 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
16 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
17 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
18 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
19 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
20 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
21 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
22 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
23 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
24 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
25 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
26 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
27 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
28 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
29 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16
30 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
31 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
32 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
33 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
34 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
35 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
36 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
37 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
38 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
39 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
40 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
41 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
42 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
43 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
44 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
45 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
46 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
47 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
48 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47
49 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35
50 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
51 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
52 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
53 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
54 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
55 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
56 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
57 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
58 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
59 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
60 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
61 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08
62 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
63 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
64 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
65 INT324927 Syt17 Positive_regulation of Bdkrb1 1 0.04 4.29 2.96
66 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
67 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
68 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
69 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
70 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
71 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9
72 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
73 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
74 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
75 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
76 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
77 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
78 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81
79 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
80 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
81 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
82 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
83 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
84 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
85 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
86 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
87 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
88 INT69057 H2-M3 Regulation of Klkb1 1 0.00 0.42 2.71
89 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
90 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
91 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62
92 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
93 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
94 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
95 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
96 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
97 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
98 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
99 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
100 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
101 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
102 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5
103 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
104 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
105 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46
106 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
107 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
108 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
109 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
110 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
111 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
112 INT318998 IFNA1 Positive_regulation of Localization of CXCL10 1 0.15 2.09 2.39
113 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
114 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
115 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
116 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
117 INT108987 Ngf Regulation of Gene_expression of Sit1 1 0.00 1.46 2.32
118 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
119 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
120 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
121 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
122 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
123 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25
124 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
125 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
126 INT34310 CRH Positive_regulation of POMC 3 0.42 0.62 2.21
127 INT312690 CP Positive_regulation of CCL20 1 0.11 8.23 2.2
128 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2
129 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
130 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
131 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
132 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
133 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
134 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
135 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
136 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
137 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
138 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
139 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
140 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
141 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
142 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
143 INT229394 TPSD1 Positive_regulation of F2RL1 2 0.00 3.11 2.14
144 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
145 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
146 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
147 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12
148 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
149 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
150 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
151 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
152 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09
153 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
154 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
155 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
156 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
157 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
158 INT107268 Binding of ITGAL and NCR3 1 0.01 2.76 2.07
159 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
160 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
161 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
162 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
163 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
164 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
165 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
166 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
167 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
168 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
169 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99
170 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
171 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
172 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
173 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
174 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
175 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
176 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
177 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
178 INT165284 Positive_regulation of Nts Positive_regulation of Crh 1 0.40 1.86 1.93
179 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
180 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
181 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
182 INT165285 Nts Positive_regulation of Crh 1 0.40 1.84 1.91
183 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
184 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
185 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
186 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
187 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
188 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
189 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86
190 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
191 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85
192 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
193 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
194 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
195 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
196 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
197 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84
198 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
199 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
200 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8

Single Events

The table below shows the top 100 pain related interactions that have been reported for inflammatory response. They are ordered first by their pain relevance and then by number of times they were reported in inflammatory response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
3 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
4 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
5 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
6 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
7 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
8 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
9 INT2649 Regulation of Calca 433 0.62 146.05 330.95
10 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
11 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56
12 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
13 INT6852 Localization of TNF 883 0.81 705.95 270.84
14 INT10832 Gene_expression of IL8 1050 0.78 698.72 270
15 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
16 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
17 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
18 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238
19 INT1562 Localization of Crh 499 0.81 126.74 236.68
20 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
21 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
22 INT6481 Binding of TNF 624 0.48 510.2 214.82
23 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
24 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
25 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
26 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
27 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
28 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
29 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07
30 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
31 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
32 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
33 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69
34 INT9660 Regulation of TNF 363 0.62 312.94 139.99
35 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52
36 INT2541 Binding of Calca 200 0.48 67.14 134.62
37 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
38 INT5008 Localization of Calca 204 0.81 80.35 125.16
39 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
40 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
41 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03
42 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
43 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
44 INT12339 Localization of IL8 437 0.81 251.87 117.39
45 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06
46 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
47 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84
48 INT12082 Localization of IL6 365 0.81 241.78 105.78
49 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74
50 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
51 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66
52 INT1898 Regulation of Crh 220 0.62 61.33 102.64
53 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62
54 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
55 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
56 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
57 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43
58 INT10166 Localization of Tnf 237 0.81 153.95 88.64
59 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32
60 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
61 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08
62 INT8650 Gene_expression of Gal 152 0.78 61.97 81.72
63 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19
64 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45
65 INT12001 Regulation of Ngf 97 0.62 54.64 76.25
66 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
67 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
68 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42
69 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
70 INT3034 Localization of Ngf 126 0.81 50.81 72.84
71 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
72 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
73 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
74 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
75 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34
76 INT6849 Localization of IL1B 229 0.81 112.56 69.63
77 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66
78 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26
79 INT7134 Localization of KNG1 127 0.79 65.73 67.97
80 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
81 INT19511 Localization of Il6 212 0.81 118.17 67.67
82 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
83 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
84 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
85 INT11937 Localization of Il6 228 0.81 139.83 64.39
86 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
87 INT65730 Gene_expression of Cnr2 129 0.78 60.15 63.1
88 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
89 INT10706 Regulation of Il6 150 0.62 93.23 62.34
90 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
91 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
92 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
93 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
94 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
95 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74
96 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
97 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74
98 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
99 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72
100 INT20266 Positive_regulation of Bdkrb1 60 0.69 63.64 56.59
101 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
102 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
103 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
104 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
105 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69
106 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
107 INT37219 Gene_expression of TACR1 56 0.78 32.4 54.16
108 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
109 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
110 INT4891 Transcription of Calca 81 0.72 35.27 53.75
111 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
112 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
113 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
114 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
115 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
116 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
117 INT8690 Localization of Tac1 71 0.80 22.98 50.75
118 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67
119 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
120 INT9210 Regulation of IL6 166 0.62 125.61 49.95
121 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
122 INT51163 Gene_expression of Gal 119 0.78 67.48 49.23
123 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
124 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
125 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
126 INT8713 Regulation of Tac1 56 0.60 25.29 45.94
127 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33
128 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
129 INT4776 Localization of TAC1 82 0.78 16.89 45.21
130 INT14853 Negative_regulation of Tac1 80 0.59 30.87 45.06
131 INT19078 Binding of Ngf 78 0.48 31.03 44.33
132 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23
133 INT109910 Gene_expression of CCL16 104 0.74 76.1 43.97
134 INT83953 Gene_expression of Cxcl2 140 0.75 113.07 43.65
135 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5
136 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
137 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07
138 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
139 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65
140 INT13354 Transcription of TNF 108 0.72 85.81 42.32
141 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
142 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
143 INT4850 Binding of Tac1 57 0.47 14.25 42.17
144 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
145 INT5454 Localization of CRH 124 0.79 79.18 41.53
146 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
147 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
148 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
149 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33
150 INT49643 Gene_expression of Bdkrb1 39 0.78 46.49 40.21
151 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
152 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84
153 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03
154 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94
155 INT5039 Positive_regulation of Gal 67 0.68 27.97 37.36
156 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2
157 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95
158 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
159 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98
160 INT8837 Positive_regulation of TAC1 59 0.67 21.94 35.97
161 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5
162 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
163 INT100733 Positive_regulation of F2RL1 62 0.70 59.14 35.22
164 INT6484 Binding of IL1B 122 0.47 75.84 35.07
165 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
166 INT17381 Gene_expression of Tbxa2r 146 0.78 65.01 34.15
167 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12
168 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
169 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52
170 INT33768 Positive_regulation of Cysltr1 87 0.46 54.66 33.52
171 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
172 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
173 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13
174 INT4727 Regulation of TAC1 60 0.47 6.74 32.83
175 INT65698 Localization of CCL2 118 0.81 77.54 32.69
176 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
177 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
178 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26
179 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
180 INT9655 Regulation of Il6 98 0.62 70.92 31.95
181 INT92837 Negative_regulation of Gene_expression of Nos2 116 0.59 59.67 31.82
182 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
183 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74
184 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72
185 INT51685 Gene_expression of LTB4R 87 0.58 68.69 31.72
186 INT35406 Localization of Tnf 94 0.81 64.63 31.65
187 INT9347 Localization of Il1b 58 0.81 26.13 31.53
188 INT22239 Negative_regulation of TAC1 52 0.57 12.96 31.41
189 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23
190 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
191 INT5418 Negative_regulation of Alox5 108 0.57 42.09 31.17
192 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16
193 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
194 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82
195 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
196 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21
197 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11
198 INT90792 Localization of Il10 144 0.80 87.88 30.03
199 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
200 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
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