GO:0006955

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Name immune response
Categary Process
Go Slim No
Go Link GO:0006955
Unique Molecular Interactions 6497
Total Molecular Interactions 9382
Total Single Events 71091
Pain Genes Associated 360

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for immune response. They are ordered first by their pain relevance and then by number of times they were reported for immune response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT51205 Binding of OPRK1 and PDYN 7 0.00 2.01 7.8
2 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73
3 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
4 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09
5 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87
6 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
7 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
8 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
9 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
10 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
11 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
12 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
13 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
14 INT40114 Binding of OPRD1 and Oprm1 2 0.00 0 4.29
15 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16
16 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
17 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
18 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97
19 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
20 INT107331 Binding of PPBP and Adarb1 1 0.01 0 3.67
21 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
22 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
23 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
24 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
25 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
26 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47
27 INT152035 Binding of HLA-A and MRAP 2 0.31 6.95 3.4
28 INT7436 CFP Positive_regulation of Binding of POMC 1 0.02 0.18 3.35
29 INT56458 Binding of GPM6A and IGHG3 4 0.02 0 3.31
30 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
31 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22
32 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
33 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
34 INT17456 Binding of CSF2 and POMC 3 0.32 4.06 3.15
35 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
36 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12
37 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
38 INT51202 Positive_regulation of Binding of OPRK1 and PDYN 3 0.00 0.63 3.1
39 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08
40 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
41 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
42 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
43 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
44 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
45 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
46 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
47 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
48 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
49 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
50 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
51 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
52 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
53 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
54 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
55 INT104218 SCD Positive_regulation of CNR2 1 0.01 2.67 2.54
56 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
57 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
58 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
59 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5
60 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
61 INT318998 IFNA1 Positive_regulation of Localization of CXCL10 1 0.15 2.09 2.39
62 INT96465 Pnoc Positive_regulation of GEM 1 0.01 0.74 2.39
63 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
64 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
65 INT350148 Binding of IL12A and ERAL1 1 0.21 8.23 2.26
66 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
67 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21
68 INT312690 CP Positive_regulation of CCL20 1 0.11 8.23 2.2
69 INT155984 Il1a Negative_regulation of Gene_expression of Cyp3a11 1 0.24 0.92 2.2
70 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
71 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
72 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
73 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
74 INT32586 H2-Ab1 Regulation of Pomc 1 0.03 0.14 2.19
75 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
76 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
77 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
78 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13
79 INT133946 Binding of DNM2 and OPRK1 1 0.11 0 2.1
80 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09
81 INT85041 Binding of IGHG3 and MAX 1 0.00 0 2.09
82 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
83 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
84 INT182200 Binding of CXCR5 and CXCL13 1 0.37 2.89 2.07
85 INT107268 Binding of ITGAL and NCR3 1 0.01 2.76 2.07
86 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
87 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
88 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
89 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
90 INT32585 H2-Ab1 Negative_regulation of Pomc 1 0.03 0.13 2
91 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
92 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
93 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
94 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
95 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
96 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
97 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
98 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
99 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
100 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
101 INT165200 Binding of CTLA4 and Crp 1 0.09 1.64 1.91
102 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
103 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
104 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86
105 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
106 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
107 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
108 INT128654 ITIH4 Regulation of Gene_expression of CCL16 1 0.02 2.69 1.79
109 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
110 INT24817 Binding of POMC and VTN 8 0.42 0.39 1.71
111 INT139190 Binding of Fadd and Fas 4 0.38 2.65 1.71
112 INT158302 Il23a Regulation of Gene_expression of Il17a 1 0.06 1.45 1.7
113 INT157459 Binding of CX3CR1 and CX3CL1 1 0.32 2.12 1.7
114 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
115 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
116 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
117 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
118 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
119 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
120 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64
121 INT172047 Binding of HLA-A and LRRC23 1 0.22 3.32 1.64
122 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
123 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
124 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
125 INT174503 Binding of HLA-B and KIR3DL1 6 0.37 3.48 1.61
126 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
127 INT107965 Binding of HLA-B and Mefv 2 0.34 3.91 1.61
128 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
129 INT81710 POMC Regulation of Gene_expression of FCGR3B 1 0.50 0.34 1.57
130 INT81712 POMC Regulation of FCGR3B 1 0.16 0.34 1.56
131 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56
132 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
133 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
134 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
135 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
136 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
137 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
138 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53
139 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
140 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
141 INT69031 IL12A Positive_regulation of IFNA1 9 0.13 4.23 1.52
142 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
143 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
144 INT260897 CRH Positive_regulation of Localization of IL8 1 0.24 0.09 1.51
145 INT253863 Binding of LBP and PNP 1 0.13 1.5 1.5
146 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
147 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
148 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5
149 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
150 INT29093 Binding of H2-Ab1 and Rbm39 1 0.06 0 1.5
151 INT229094 Binding of IL1RN and Il1r1 1 0.01 1.9 1.5
152 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
153 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49
154 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
155 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
156 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
157 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
158 INT21536 Binding of Il2 and Il1 1 0.28 0 1.47
159 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
160 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46
161 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
162 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46
163 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
164 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
165 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
166 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
167 INT158282 Binding of Penk and Csf2 1 0.33 0.87 1.44
168 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
169 INT238005 Binding of Cxcr3 and Cxcl10 2 0.38 3.73 1.42
170 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
171 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
172 INT222213 TFAM Positive_regulation of Gene_expression of Ccr1 1 0.02 3.96 1.4
173 INT133937 Binding of OPRK1 and ARFGEF1 1 0.01 0 1.39
174 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
175 INT55837 Binding of HLA-B and PHB2 3 0.20 3.52 1.37
176 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
177 INT51203 Binding of OPRK1 and OPRM1 2 0.29 0.3 1.36
178 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
179 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
180 INT160590 CSF2 Positive_regulation of Gene_expression of OPRM1 1 0.16 0.54 1.35
181 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
182 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35
183 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
184 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
185 INT160589 IL4 Positive_regulation of Gene_expression of OPRM1 1 0.13 0.54 1.35
186 INT86172 Pdyn Positive_regulation of Gene_expression of Il2 1 0.20 0 1.33
187 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33
188 INT143999 IK Regulation of Gene_expression of Penk 1 0.04 0 1.33
189 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
190 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
191 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
192 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
193 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31
194 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31
195 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
196 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
197 INT201942 DPP4 Negative_regulation of CXCL10 1 0.33 0.9 1.3
198 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
199 INT128310 Oprm1 Positive_regulation of Oprm1 1 0.00 0.1 1.29
200 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28

Single Events

The table below shows the top 100 pain related interactions that have been reported for immune response. They are ordered first by their pain relevance and then by number of times they were reported in immune response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10832 Gene_expression of IL8 1050 0.78 698.72 270
2 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
3 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
4 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
5 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
6 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
7 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
8 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
9 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
10 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69
11 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69
12 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52
13 INT1878 Binding of HLA-B 440 0.48 321.16 127.36
14 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
15 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
16 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
17 INT12339 Localization of IL8 437 0.81 251.87 117.39
18 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12
19 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
20 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62
21 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
22 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
23 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
24 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89
25 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37
26 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96
27 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
28 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
29 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92
30 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
31 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38
32 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34
33 INT6849 Localization of IL1B 229 0.81 112.56 69.63
34 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
35 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
36 INT19511 Localization of Il6 212 0.81 118.17 67.67
37 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
38 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
39 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73
40 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46
41 INT11807 Gene_expression of Il2 266 0.78 112 64.97
42 INT11937 Localization of Il6 228 0.81 139.83 64.39
43 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
44 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
45 INT10706 Regulation of Il6 150 0.62 93.23 62.34
46 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62
47 INT20964 Gene_expression of OPRK1 96 0.78 23.54 58.18
48 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74
49 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72
50 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
51 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69
52 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
53 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
54 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
55 INT52264 Gene_expression of IK 180 0.77 90.87 51.87
56 INT12345 Gene_expression of Il2 142 0.78 59.17 51.21
57 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
58 INT10304 Binding of OPRK1 89 0.48 9.28 49.42
59 INT32718 Gene_expression of OPRD1 82 0.76 9.43 48.38
60 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
61 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
62 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33
63 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01
64 INT29105 Positive_regulation of OPRK1 68 0.70 7.06 44.69
65 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23
66 INT109910 Gene_expression of CCL16 104 0.74 76.1 43.97
67 INT83953 Gene_expression of Cxcl2 140 0.75 113.07 43.65
68 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38
69 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32
70 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07
71 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
72 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33
73 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
74 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97
75 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
76 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74
77 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
78 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
79 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16
80 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
81 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84
82 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77
83 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2
84 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95
85 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17
86 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
87 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5
88 INT6484 Binding of IL1B 122 0.47 75.84 35.07
89 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78
90 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67
91 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12
92 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05
93 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
94 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72
95 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66
96 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
97 INT10763 Localization of IL2 157 0.80 81.11 33.21
98 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07
99 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
100 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
101 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26
102 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22
103 INT9655 Regulation of Il6 98 0.62 70.92 31.95
104 INT51685 Gene_expression of LTB4R 87 0.58 68.69 31.72
105 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7
106 INT35406 Localization of Tnf 94 0.81 64.63 31.65
107 INT9347 Localization of Il1b 58 0.81 26.13 31.53
108 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4
109 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
110 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
111 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82
112 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75
113 INT7845 Regulation of OPRK1 44 0.62 4.54 30.49
114 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21
115 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04
116 INT90792 Localization of Il10 144 0.80 87.88 30.03
117 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96
118 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44
119 INT3841 Gene_expression of FCGR3B 117 0.75 58.99 28.87
120 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58
121 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
122 INT82882 Localization of Ccl2 61 0.80 41.96 28
123 INT14690 Localization of CSF2 124 0.80 85.17 27.26
124 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81
125 INT5966 Localization of Il1a 50 0.78 22.91 26.54
126 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39
127 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
128 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15
129 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95
130 INT6934 Binding of OPRD1 51 0.48 7.72 25.73
131 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
132 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11
133 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01
134 INT81496 Gene_expression of CNR2 68 0.75 30.04 24.92
135 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
136 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71
137 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
138 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14
139 INT10835 Regulation of IL8 79 0.49 53.04 24.14
140 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
141 INT8775 Binding of IGHE 167 0.48 102.61 23.54
142 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54
143 INT66026 Gene_expression of Cxcl1 74 0.78 31.87 23.37
144 INT100026 Gene_expression of Tnfrsf1b 73 0.72 43.26 23.23
145 INT134651 Binding of TLR4 89 0.48 66.96 23.19
146 INT30386 Negative_regulation of OPRD1 33 0.52 4.34 23.06
147 INT94335 Positive_regulation of CXCL10 71 0.58 50.69 23
148 INT19330 Binding of HLA-A 99 0.48 76.26 22.85
149 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79
150 INT48081 Localization of Il1b 46 0.80 21.59 22.4
151 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
152 INT139664 Gene_expression of CCL18 83 0.76 37.05 21.95
153 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
154 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63
155 INT9079 Gene_expression of PPBP 52 0.75 31.2 21.52
156 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48
157 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
158 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31
159 INT1876 Positive_regulation of HLA-B 82 0.69 52.16 21.08
160 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96
161 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85
162 INT52106 Negative_regulation of Localization of IL8 57 0.52 22.81 20.8
163 INT614 Gene_expression of Cxcl2 29 0.76 25.53 20.8
164 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
165 INT15796 Regulation of IL2 66 0.61 25.43 20.62
166 INT78901 Localization of CCL5 67 0.78 40.79 20.59
167 INT20379 Localization of Il4 85 0.73 51.22 20.55
168 INT51474 Binding of Il6 55 0.48 44.99 20.52
169 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51
170 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39
171 INT57257 Gene_expression of IL7 69 0.62 50.24 20.36
172 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
173 INT49985 Transcription of Il6 62 0.72 40.13 20.29
174 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98
175 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81
176 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79
177 INT157463 Gene_expression of CX3CL1 55 0.62 69.05 19.75
178 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
179 INT7994 Gene_expression of Lta 113 0.67 69.81 19.59
180 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58
181 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44
182 INT74286 Regulation of Il10 42 0.44 28.06 19.44
183 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29
184 INT756 Gene_expression of C3 138 0.75 100.6 19.2
185 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19
186 INT5160 Localization of PTAFR 61 0.80 42.6 19.16
187 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01
188 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93
189 INT19509 Localization of Ifng 55 0.78 28.25 18.67
190 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65
191 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
192 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46
193 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46
194 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
195 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
196 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
197 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24
198 INT182217 Gene_expression of CCR9 8 0.75 44.81 18.15
199 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01
200 INT7439 Positive_regulation of CFP 52 0.67 19.97 17.87
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