GO:0006957

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Name complement activation, alternative pathway
Categary Process
Go Slim No
Go Link GO:0006957
Unique Molecular Interactions 193
Total Molecular Interactions 256
Total Single Events 2192
Pain Genes Associated 20

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for complement activation, alternative pathway. They are ordered first by their pain relevance and then by number of times they were reported for complement activation, alternative pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7436 CFP Positive_regulation of Binding of POMC 1 0.02 0.18 3.35
2 INT231969 Binding of Cfp and Cpn1 1 0.05 1.38 2.25
3 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2
4 INT329962 Binding of C5 and HEPACAM 1 0.03 2.25 1.06
5 INT193291 Binding of CAP1 and Cfd 1 0.02 0.13 0.91
6 INT193277 Binding of Cfd and Brs3 1 0.01 0.13 0.91
7 INT210984 Cfp Positive_regulation of Positive_regulation of Dio1 1 0.07 0.81 0.75
8 INT252858 C5 Negative_regulation of Positive_regulation of Trpa1 1 0.02 0.78 0.74
9 INT46964 C3 Positive_regulation of Tcm 1 0.00 1.26 0.66
10 INT30129 Binding of C3 and Gast 1 0.06 0.09 0.62
11 INT149479 CEBPD Positive_regulation of C3 1 0.30 0.14 0.57
12 INT313650 Binding of C8A and TRGC1 1 0.01 0.49 0.5
13 INT135378 Binding of Cfb and Oprk1 1 0.01 0.31 0.49
14 INT331731 Binding of C3 and CD79A 1 0.02 0.85 0.46
15 INT352387 Binding of CFP and HPSE 1 0.01 1.25 0.46
16 INT218783 Binding of Faah and Cfp 1 0.04 0.55 0.45
17 INT329960 Binding of C5 and TRAF1 1 0.32 1.04 0.42
18 INT329958 Binding of C5 and STAT4 1 0.33 0.93 0.41
19 INT203140 Binding of C5ar1 and C5 1 0.39 0.81 0.38
20 INT320694 C5 Regulation of Gene_expression of Il2 1 0.03 2.15 0.34
21 INT320692 C5 Regulation of Gene_expression of Il12a 1 0.03 2.15 0.34
22 INT320693 C5 Regulation of Gene_expression of Il6 1 0.04 2.15 0.34
23 INT155166 Binding of C2 and C3 1 0.40 0 0.34
24 INT320696 C5 Regulation of Gene_expression of TNF 1 0.34 2.15 0.34
25 INT320691 C5 Regulation of Gene_expression of Il1 1 0.06 2.15 0.34
26 INT340839 Binding of NOVA2 and Regulation of Cfp 1 0.02 0 0.32
27 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3
28 INT116358 Binding of C3 and ELANE 1 0.12 0 0.29
29 INT116356 Positive_regulation of Binding of C3 and ELANE 1 0.16 0 0.29
30 INT321601 Binding of C3 and PRTN3 1 0.00 0.99 0.27
31 INT24223 Ifng Negative_regulation of Gene_expression of C3 1 0.01 0 0.26
32 INT281798 CFD Regulation of Positive_regulation of Chrna4 1 0.01 0.24 0.24
33 INT238260 Positive_regulation of pma Negative_regulation of Transcription of C3 1 0.02 0.12 0.23
34 INT333394 CFD Negative_regulation of Gene_expression of Cat 1 0.03 0.79 0.22
35 INT340840 NOVA2 Regulation of Cfp 1 0.02 0 0.22
36 INT333397 CFD Negative_regulation of Gene_expression of Nos2 1 0.04 0.8 0.22
37 INT332013 Hc Regulation of Binding of C3ar1 1 0.12 1.11 0.21
38 INT332016 C3ar1 Regulation of Binding of Hc 1 0.12 1.11 0.21
39 INT309661 C5 Positive_regulation of Phosphorylation of Akt1 1 0.51 0.45 0.21
40 INT218510 Binding of C3 and Cfb 1 0.02 0.53 0.2
41 INT181082 Binding of C3 and C3ar1 1 0.03 1.31 0.19
42 INT279507 Serping1 Negative_regulation of Gene_expression of C3 1 0.03 1.12 0.19
43 INT183443 C7 Positive_regulation of POSTN 1 0.00 0 0.19
44 INT279500 Serping1 Negative_regulation of Transcription of C3 1 0.03 1.12 0.19
45 INT277112 Binding of AMD1 and CFH 1 0.16 2.45 0.18
46 INT229928 Binding of C3 and CFH 1 0.07 1.35 0.17
47 INT229931 Negative_regulation of Binding of C3 and CFH 1 0.08 1.35 0.17
48 INT258340 Binding of Ms4a1 and Cfb 1 0.04 0.32 0.16
49 INT244840 Lbx1 Negative_regulation of C9 1 0.13 0.09 0.16
50 INT333393 CFD Positive_regulation of Gene_expression of Timp1 1 0.07 0.82 0.16
51 INT344590 Binding of IFN1@ and C3 1 0.32 0.3 0.16
52 INT322265 Binding of MPZ and VSIG4 1 0.29 1.63 0.14
53 INT218499 Cfb Negative_regulation of ap 1 0.00 0.74 0.13
54 INT333396 CFD Positive_regulation of Bcl2l1 1 0.05 0.98 0.13
55 INT34378 Binding of Cfp and Prkcdbp 1 0.25 0.15 0.12
56 INT34377 Positive_regulation of Binding of Cfp and Prkcdbp 1 0.33 0.15 0.12
57 INT289404 Mthfd1 Positive_regulation of Hc 1 0.04 0.58 0.12
58 INT220905 Cfb Positive_regulation of C3 1 0.06 0.91 0.11
59 INT309662 C5 Positive_regulation of Akt1 1 0.30 0.43 0.11
60 INT332014 Binding of Cfi and Cfb 1 0.00 0.29 0.09
61 INT332019 Binding of C3ar1 and Cfb 1 0.03 0.29 0.09
62 INT45452 Binding of C2 and C3 1 0.34 0.08 0.08
63 INT41832 Binding of ALB and C5 1 0.41 0.07 0.08
64 INT41831 Binding of ALB and C3 1 0.22 0.07 0.08
65 INT269508 Binding of HTN1 and CFP 1 0.00 0 0.08
66 INT291040 Binding of CFH and INS 1 0.25 1.32 0.08
67 INT243257 Thy1 Regulation of Gene_expression of Cfp 1 0.42 1.49 0.08
68 INT279502 Binding of C2 and Hc 1 0.01 0.2 0.07
69 INT243255 Binding of Cfp and Pou4f1 1 0.23 0.6 0.07
70 INT196592 Binding of CFD and GHRH 1 0.02 1.88 0.07
71 INT243253 Binding of Calb2 and Cfp 1 0.22 0.61 0.07
72 INT243254 Binding of Cfp and NeuN 1 0.29 0.6 0.07
73 INT243256 Binding of Nefl and Cfp 1 0.24 0.6 0.07
74 INT313649 C8A Regulation of ISYNA1 1 0.00 0.12 0.06
75 INT218511 Cfb Positive_regulation of C5 1 0.01 0.29 0.06
76 INT218503 Cfb Positive_regulation of C3 1 0.01 0.29 0.06
77 INT313652 C8A Regulation of CPOX 1 0.00 0.11 0.06
78 INT299703 ECB2 Negative_regulation of Binding of C5 1 0.00 0.39 0.06
79 INT229977 Binding of amd and Cfb 1 0.03 2.78 0.06
80 INT229982 Binding of C3 and amd 1 0.02 1.14 0.06
81 INT278984 Binding of CFH and NCS1 1 0.02 0.63 0.05
82 INT136096 Binding of CFH and CFI 1 0.04 2.28 0.05
83 INT171543 IL4 Positive_regulation of Transcription of C3 1 0.28 0 0.05
84 INT171542 IL4 Positive_regulation of Gene_expression of C3 1 0.19 0 0.05
85 INT342886 Binding of C3 and CD40 1 0.02 0.66 0.05
86 INT245218 Binding of C3 and C5AR1 2 0.29 2.94 0.04
87 INT245216 Binding of C3 and C3AR1 1 0.19 1.21 0.04
88 INT317417 Binding of CFH and MMP9 1 0.10 1.27 0.04
89 INT281652 GOPC Positive_regulation of C3 1 0.22 0.22 0.04
90 INT198595 Binding of CFH and CFHR1 3 0.41 1.36 0.03
91 INT320991 C5AR1 Regulation of C5 1 0.05 0 0.03
92 INT313656 C8A Regulation of Gene_expression of ISYNA1 1 0.00 0.06 0.03
93 INT279593 Binding of C4B and Cfb 1 0.00 1.18 0.03
94 INT334869 Nrg1 Positive_regulation of Phosphorylation of C3 1 0.08 0 0.03
95 INT289410 Binding of C3 and Cfb 1 0.01 0.36 0.03
96 INT229983 Binding of CFH and Crp 2 0.14 1.48 0
97 INT279698 Hc Regulation of Trpv1 1 0.01 0 0
98 INT279533 CFH Positive_regulation of C3 1 0.07 1.8 0
99 INT229934 Binding of C3 and GPI 1 0.01 0 0
100 INT218506 Binding of LCN1 and Cfb 1 0.04 0.25 0
101 INT229923 Binding of ABCA1 and C9 1 0.00 0.74 0
102 INT299709 S100A12 Regulation of CFB 1 0.00 0.05 0
103 INT289413 Binding of C4A and Cfb 1 0.02 0.26 0
104 INT299700 FGL1 Regulation of CFB 1 0.00 0.05 0
105 INT289412 Binding of C4A and C3 1 0.11 0.26 0
106 INT299705 C5 Positive_regulation of Positive_regulation of C5AR1 1 0.03 0.1 0
107 INT338513 Binding of CFHR1 and CFHR5 1 0.13 0.43 0
108 INT254866 Positive_regulation of C3 Negative_regulation of Rock1 1 0.02 0 0
109 INT353106 Binding of amd and C3 1 0.09 1.69 0
110 INT218509 Binding of BCR and Cfb 1 0.00 0.18 0
111 INT198593 Binding of CFH and VHL 1 0.02 0.27 0
112 INT218508 Negative_regulation of Binding of C3 and Cfb 1 0.01 0 0
113 INT254851 C3 Negative_regulation of Rhoa 1 0.06 0 0
114 INT218505 Binding of C5 and Cfb 1 0.01 0.29 0
115 INT275841 Cfp Positive_regulation of Ncapg2 1 0.02 0.75 0
116 INT170841 Binding of CFD and IFI27 1 0.07 0.37 0
117 INT239913 Binding of C7 and C8B 1 0.18 0.06 0
118 INT279501 C3ar1 Positive_regulation of C3 1 0.01 0 0
119 INT333395 Binding of CFD and Aes 1 0.03 0.24 0
120 INT218514 BCR Negative_regulation of Binding of Cfb 1 0.00 0.18 0
121 INT254854 Positive_regulation of C3 Negative_regulation of Rhoa 1 0.05 0 0
122 INT279695 Hc Negative_regulation of Car2 1 0.02 0 0
123 INT254861 C3 Negative_regulation of Rock1 1 0.02 0 0
124 INT279530 MBL2 Positive_regulation of Positive_regulation of C3 1 0.26 1.71 0
125 INT279696 Hc Negative_regulation of Trpv1 1 0.01 0 0
126 INT229930 C3AR1 Positive_regulation of C3 1 0.00 0 0
127 INT299698 Binding of CFB and PSMC2 1 0.00 0.14 0
128 INT313654 C8A Negative_regulation of PLA2G2D 1 0.02 0 0
129 INT229922 Binding of C9 and CD59 1 0.08 0.72 0
130 INT283062 ERCC8 Positive_regulation of CFH 1 0.02 1.88 0
131 INT198594 Binding of CFH and MIR1197 1 0.01 0.48 0
132 INT313657 C8A Negative_regulation of TRGC1 1 0.01 0 0
133 INT338510 Binding of CFH and CFHR5 1 0.13 0.23 0
134 INT218532 Binding of C5 and LCN1 1 0.06 0.49 0
135 INT279694 Hc Negative_regulation of Catsper1 1 0.05 0 0
136 INT275840 Cfp Positive_regulation of Tlr2 1 0.02 0.75 0
137 INT289411 Binding of C9 and Ivns1abp 1 0.01 0.54 0
138 INT220907 Binding of C4bp and Cfb 1 0.08 0.52 0
139 INT279534 Binding of CFH and PTPN11 1 0.02 2.54 0
140 INT234306 Binding of Gria4 and Hc 1 0.01 0 0
141 INT299707 ECB2 Regulation of CFB 1 0.00 0 0
142 INT289414 C4A Positive_regulation of Cfb 1 0.03 0.26 0
143 INT309728 TRPV4 Positive_regulation of CFP 1 0.10 0 0
144 INT279539 Binding of CFD and MBL2 1 0.09 0.08 0
145 INT229932 C4B Positive_regulation of C3 1 0.07 0 0
146 INT345059 Binding of C3 and C2 1 0.00 0 0
147 INT269509 Binding of CFP and fc 1 0.00 0 0
148 INT229929 Binding of C4B and CFH 1 0.09 0 0
149 INT338511 Binding of CFHR2 and CFHR5 1 0.11 0.66 0
150 INT279592 Positive_regulation of Binding of C4B and Cfb 1 0.00 0.74 0
151 INT338514 Binding of FHL1 and CFH 1 0.08 0.37 0
152 INT338512 Binding of CFH and CFHR2 1 0.20 0.67 0
153 INT279537 ICAM3 Positive_regulation of C3 1 0.06 0.85 0
154 INT218512 Binding of TCN2 and Cfb 1 0.00 0 0
155 INT299708 Binding of C3 and PSMC2 1 0.00 0.14 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for complement activation, alternative pathway. They are ordered first by their pain relevance and then by number of times they were reported in complement activation, alternative pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT756 Gene_expression of C3 138 0.75 100.6 19.2
2 INT7439 Positive_regulation of CFP 52 0.67 19.97 17.87
3 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63
4 INT4297 Negative_regulation of CFP 21 0.42 12.7 10.29
5 INT34372 Gene_expression of Cfp 102 0.67 37.66 8.72
6 INT573 Negative_regulation of C3 60 0.59 41.37 7.78
7 INT178198 Gene_expression of C3 62 0.78 39.5 7.69
8 INT1120 Gene_expression of C3 33 0.67 22.86 7.56
9 INT34370 Positive_regulation of Cfp 26 0.46 15.21 6.12
10 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74
11 INT68789 Regulation of CFP 17 0.51 4.76 3.98
12 INT43931 Binding of CFH 49 0.48 31.85 3.96
13 INT210975 Regulation of Cfp 10 0.24 5.3 3.93
14 INT6507 Binding of C5 23 0.48 15.35 3.91
15 INT7437 Gene_expression of CFP 21 0.65 4.93 3.89
16 INT179542 Positive_regulation of C3 27 0.52 19.39 3.83
17 INT69904 Binding of Hc 11 0.35 7.79 3.69
18 INT107074 Gene_expression of C5 14 0.75 9.87 3.64
19 INT135963 Negative_regulation of Hc 19 0.42 12.36 3.63
20 INT27660 Binding of CFP 21 0.40 12.47 3.51
21 INT16236 Negative_regulation of CFH 31 0.57 19.59 3.36
22 INT16234 Positive_regulation of CFH 25 0.50 26.05 3.33
23 INT146890 Gene_expression of Cfd 15 0.66 4.42 3.28
24 INT184365 Negative_regulation of C3 19 0.43 13.86 2.89
25 INT9460 Positive_regulation of C3 6 0.69 3.96 2.81
26 INT145774 Positive_regulation of C5 7 0.67 4.88 2.79
27 INT64147 Gene_expression of C5 15 0.60 16.8 2.78
28 INT121683 Gene_expression of Hc 23 0.75 7.15 2.7
29 INT155160 Binding of C3 20 0.47 7.77 2.61
30 INT1829 Gene_expression of CFH 71 0.75 64.24 2.49
31 INT184378 Binding of Cfb 54 0.20 12.49 2.36
32 INT29094 Binding of C3 39 0.37 12.65 2.27
33 INT45004 Gene_expression of Cfb 28 0.37 15.06 1.99
34 INT35689 Localization of C3 17 0.75 5.3 1.98
35 INT16385 Regulation of C3 20 0.41 9.98 1.92
36 INT135961 Positive_regulation of Hc 8 0.67 3.67 1.87
37 INT207035 Gene_expression of CFB 4 0.63 18.4 1.72
38 INT565 Negative_regulation of Cfb 18 0.13 6.77 1.69
39 INT26426 Localization of C5 5 0.78 3.87 1.61
40 INT168558 Positive_regulation of Gene_expression of Cfp 10 0.43 4.54 1.59
41 INT212790 Regulation of C5 6 0.24 6.04 1.59
42 INT182037 Localization of C3 10 0.68 6.69 1.54
43 INT46389 Positive_regulation of Cfb 20 0.23 8.29 1.49
44 INT170853 Positive_regulation of Gene_expression of CFD 7 0.23 9.89 1.41
45 INT25621 Localization of Cfb 8 0.20 2.23 1.4
46 INT125980 Binding of CFD 8 0.42 10.96 1.39
47 INT10885 Negative_regulation of C3 9 0.38 11.86 1.35
48 INT179539 Positive_regulation of Gene_expression of C3 9 0.70 5.98 1.32
49 INT242105 Positive_regulation of Positive_regulation of CFP 5 0.49 1.93 1.32
50 INT148212 Negative_regulation of Gene_expression of C3 2 0.43 5.47 1.24
51 INT218779 Negative_regulation of Cfp 7 0.14 2.89 1.2
52 INT107942 Positive_regulation of C5 9 0.50 6.86 1.19
53 INT185943 Gene_expression of C8A 3 0.06 3.14 1.16
54 INT39818 Positive_regulation of Cfd 8 0.45 3.36 1.15
55 INT168559 Negative_regulation of Gene_expression of Cfp 5 0.37 2.07 1.14
56 INT93055 Regulation of C3 4 0.40 1.81 1.12
57 INT227492 Negative_regulation of Regulation of CFP 1 0.03 1.25 1.11
58 INT59889 Regulation of Cfd 3 0.39 0.21 1.1
59 INT146891 Positive_regulation of Gene_expression of Cfd 2 0.39 0.75 1.1
60 INT209099 Binding of Cfd 14 0.15 3.75 1.08
61 INT46044 Positive_regulation of Gene_expression of C3 23 0.53 20.07 1.06
62 INT165275 Regulation of Cfb 5 0.06 0.83 1.06
63 INT145773 Positive_regulation of Localization of C5 1 0.49 1.15 1.06
64 INT116360 Protein_catabolism of C3 19 0.64 4.4 1
65 INT238250 Regulation of Gene_expression of C3 2 0.27 2.16 0.98
66 INT68788 Localization of CFP 7 0.63 1.07 0.93
67 INT218778 Positive_regulation of Regulation of Cfp 1 0.07 0.31 0.92
68 INT111668 Binding of C3 4 0.36 3.84 0.87
69 INT35292 Negative_regulation of C5 7 0.43 5.3 0.86
70 INT79956 Positive_regulation of Positive_regulation of C3 4 0.35 4.17 0.86
71 INT28689 Negative_regulation of Positive_regulation of C3 4 0.23 1.28 0.85
72 INT193272 Regulation of Gene_expression of Cfd 1 0.20 0.05 0.85
73 INT126030 Regulation of CFD 4 0.21 3.92 0.83
74 INT184351 Localization of Hc 2 0.20 2.33 0.83
75 INT269693 Regulation of Negative_regulation of Hc 1 0.00 0.09 0.83
76 INT313673 Negative_regulation of C8A 1 0.04 0.85 0.82
77 INT329967 Positive_regulation of Gene_expression of C5 1 0.42 1.63 0.81
78 INT70744 Regulation of CFH 12 0.41 7.38 0.8
79 INT193273 Negative_regulation of Gene_expression of Cfd 2 0.19 1.19 0.79
80 INT248227 Protein_catabolism of CFD 4 0.46 2.48 0.77
81 INT149485 Regulation of Gene_expression of C3 5 0.60 3.39 0.75
82 INT95929 Binding of Cfp 6 0.27 7.12 0.74
83 INT179530 Transcription of C3 4 0.69 2.59 0.7
84 INT47048 Regulation of Positive_regulation of CFH 1 0.29 0.27 0.7
85 INT116361 Positive_regulation of Protein_catabolism of C3 6 0.45 1.86 0.69
86 INT121684 Positive_regulation of Gene_expression of Hc 3 0.67 1.56 0.69
87 INT161201 Localization of C5 2 0.75 0.93 0.69
88 INT252856 Positive_regulation of Positive_regulation of C5 1 0.02 0.95 0.67
89 INT157225 Negative_regulation of Gene_expression of Hc 2 0.12 1.12 0.66
90 INT203146 Protein_catabolism of C5 1 0.64 1.62 0.64
91 INT166437 Binding of C5 4 0.36 3.28 0.63
92 INT184367 Protein_catabolism of Hc 4 0.26 2.66 0.6
93 INT107652 Gene_expression of C7 4 0.60 2.06 0.56
94 INT46173 Transcription of C3 4 0.61 3.54 0.53
95 INT85081 Protein_catabolism of C5 5 0.19 1.34 0.5
96 INT45447 Positive_regulation of Gene_expression of C3 2 0.42 0.9 0.49
97 INT218780 Positive_regulation of Binding of Cfp 1 0.07 1.55 0.47
98 INT218781 Negative_regulation of Regulation of Cfp 1 0.06 0.56 0.47
99 INT185946 Positive_regulation of C9 6 0.23 6.51 0.46
100 INT185951 Gene_expression of C9 7 0.65 5.84 0.45
101 INT46045 Negative_regulation of Gene_expression of C3 5 0.30 3.15 0.45
102 INT34374 Regulation of Gene_expression of Cfp 5 0.39 0.88 0.43
103 INT220886 Regulation of C3 2 0.36 1.04 0.43
104 INT59890 Regulation of Regulation of Cfd 1 0.39 0.07 0.43
105 INT241407 Phosphorylation of C3 2 0.24 0.16 0.42
106 INT229119 Negative_regulation of Localization of CFP 1 0.12 0.42 0.42
107 INT238253 Localization of C3 1 0.37 1.76 0.41
108 INT196594 Localization of CFD 4 0.65 4.36 0.39
109 INT27059 Negative_regulation of C5 2 0.42 1.87 0.35
110 INT179532 Protein_catabolism of C3 5 0.26 1.61 0.34
111 INT1121 Protein_catabolism of C3 1 0.96 1.8 0.34
112 INT207775 Negative_regulation of Gene_expression of C5 4 0.42 2.08 0.33
113 INT157615 Regulation of C9 1 0.00 0 0.33
114 INT242104 Transcription of CFP 2 0.44 0.86 0.32
115 INT279571 Regulation of Gene_expression of CFD 2 0.21 2.86 0.31
116 INT116867 Positive_regulation of Gene_expression of CFH 11 0.67 11.42 0.3
117 INT23453 Negative_regulation of Gene_expression of CFP 2 0.31 0.5 0.3
118 INT46174 Positive_regulation of Transcription of C3 1 0.13 0.25 0.3
119 INT244267 Negative_regulation of Positive_regulation of CFP 1 0.05 0.87 0.3
120 INT126999 Positive_regulation of Gene_expression of Cfb 4 0.28 2.37 0.29
121 INT218463 Negative_regulation of Binding of Cfb 7 0.08 2.31 0.28
122 INT184346 Positive_regulation of Binding of Cfb 2 0.10 0.83 0.28
123 INT54883 Positive_regulation of Gene_expression of CFP 2 0.49 0.61 0.26
124 INT313683 Binding of C8A 1 0.03 0.07 0.26
125 INT238247 Transcription of C3 1 0.43 0.12 0.23
126 INT238248 Negative_regulation of Transcription of C3 1 0.26 0.12 0.23
127 INT34371 Negative_regulation of Positive_regulation of Cfp 1 0.38 0.34 0.23
128 INT244261 Positive_regulation of Binding of CFP 1 0.06 0.13 0.22
129 INT198564 Regulation of C9 1 0.14 1.67 0.22
130 INT229118 Regulation of Regulation of CFP 1 0.20 0.25 0.22
131 INT198562 Positive_regulation of Regulation of C9 1 0.23 1.68 0.22
132 INT313679 Regulation of C8A 1 0.04 0.46 0.22
133 INT181039 Negative_regulation of Positive_regulation of C3 1 0.32 1.42 0.22
134 INT135960 Regulation of Hc 2 0.44 1.28 0.21
135 INT236354 Negative_regulation of Negative_regulation of C3 2 0.25 2.19 0.21
136 INT245266 Positive_regulation of Localization of C3 1 0.23 1.11 0.21
137 INT185412 Negative_regulation of CFD 5 0.27 3.49 0.2
138 INT181041 Negative_regulation of Gene_expression of C3 1 0.32 1.37 0.2
139 INT238246 Regulation of Gene_expression of C5 1 0.12 0 0.19
140 INT291074 Positive_regulation of Gene_expression of CFB 1 0.45 3.77 0.18
141 INT212788 Regulation of Regulation of C5 1 0.24 0.48 0.18
142 INT146898 Positive_regulation of Binding of CFH 3 0.44 2.01 0.17
143 INT212789 Negative_regulation of Gene_expression of C5 2 0.38 1.04 0.17
144 INT146899 Positive_regulation of Positive_regulation of CFH 2 0.50 1.37 0.17
145 INT230874 Gene_expression of C9 4 0.23 1.88 0.16
146 INT220895 Negative_regulation of Binding of C3 3 0.28 0.95 0.16
147 INT279586 Negative_regulation of Gene_expression of CFD 3 0.20 3.99 0.16
148 INT185947 Positive_regulation of Gene_expression of C9 2 0.23 1.43 0.16
149 INT244744 Positive_regulation of C9 1 0.13 0.09 0.16
150 INT198561 Regulation of Gene_expression of C9 1 0.23 1 0.16
151 INT218447 Protein_catabolism of Cfb 5 0.08 1.2 0.15
152 INT125712 Regulation of C5 1 0.07 0.07 0.15
153 INT309647 Regulation of Positive_regulation of C5 1 0.44 0.46 0.15
154 INT322279 Binding of VSIG4 1 0.29 1.63 0.14
155 INT79957 Regulation of Positive_regulation of C3 2 0.32 1.55 0.13
156 INT198600 Negative_regulation of Gene_expression of CFH 4 0.41 3.25 0.12
157 INT250728 Negative_regulation of Negative_regulation of CFH 1 0.41 1.57 0.12
158 INT181582 Phosphorylation of C3 1 0.34 1.2 0.12
159 INT196112 Transcription of Hc 1 0.17 0.08 0.11
160 INT194167 Protein_catabolism of CFH 2 0.59 0.63 0.09
161 INT313672 Positive_regulation of Binding of C8A 1 0.04 0 0.09
162 INT1122 Positive_regulation of Protein_catabolism of C3 1 0.45 0.45 0.09
163 INT273599 Regulation of Gene_expression of CFP 1 0.07 0.93 0.08
164 INT243242 Localization of Cfp 3 0.69 0.82 0.07
165 INT309187 Positive_regulation of Localization of Cfp 1 0.26 0.1 0.07
166 INT230875 Binding of C9 2 0.11 1.2 0.06
167 INT334858 Positive_regulation of Phosphorylation of C3 1 0.13 0 0.06
168 INT306095 Phosphorylation of Cfp 1 0.15 0 0.06
169 INT256428 Positive_regulation of CFD 4 0.15 3.67 0.05
170 INT198598 Transcription of CFH 3 0.69 3.21 0.05
171 INT210488 Phosphorylation of CFH 1 0.04 0.48 0.05
172 INT218444 Regulation of Protein_catabolism of Cfb 1 0.03 0.22 0.05
173 INT231583 Regulation of Positive_regulation of CFP 1 0.38 0.14 0.05
174 INT218442 Regulation of Positive_regulation of Cfb 1 0.06 0.22 0.05
175 INT198606 Localization of CFH 8 0.65 4.37 0.04
176 INT218489 Negative_regulation of Localization of C3 1 0.08 0.24 0.04
177 INT196595 Regulation of Localization of CFD 1 0.39 2.03 0.04
178 INT196593 Phosphorylation of CFD 1 0.55 0.84 0.04
179 INT218479 Negative_regulation of Protein_catabolism of C3 1 0.09 0.24 0.04
180 INT218450 Negative_regulation of Localization of Cfb 1 0.05 0.24 0.04
181 INT247840 Regulation of Gene_expression of C3 1 0.45 0.13 0.04
182 INT207034 Binding of CFB 3 0.17 0.61 0.03
183 INT218481 Positive_regulation of Binding of C3 2 0.35 1.23 0.03
184 INT334843 Negative_regulation of Phosphorylation of C3 1 0.15 0 0.03
185 INT246352 Positive_regulation of Regulation of C3 1 0.03 1.05 0.03
186 INT218480 Negative_regulation of Binding of C3 5 0.10 1.54 0
187 INT229966 Binding of C9 3 0.47 2.22 0
188 INT229958 Negative_regulation of CFB 3 0.01 0.06 0
189 INT218465 Regulation of Binding of Cfb 2 0.05 0 0
190 INT185944 Positive_regulation of C7 2 0.33 0.48 0
191 INT198607 Regulation of Gene_expression of CFH 2 0.27 2.16 0
192 INT198603 Positive_regulation of Transcription of CFH 2 0.50 2 0
193 INT230876 Localization of C9 2 0.22 0.43 0
194 INT135962 Regulation of Gene_expression of Hc 2 0.60 0.71 0
195 INT345382 Localization of Cfd 1 0.09 0 0
196 INT279566 Negative_regulation of Transcription of C3 1 0.30 1.49 0
197 INT218495 Negative_regulation of Negative_regulation of C3 1 0.08 0 0
198 INT218437 Positive_regulation of Negative_regulation of Cfb 1 0.06 0.16 0
199 INT239943 Binding of C8B 1 0.26 0.11 0
200 INT313681 Positive_regulation of C8A 1 0.03 0 0
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