GO:0006968

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Name cellular defense response
Categary Process
Go Slim No
Go Link GO:0006968
Unique Molecular Interactions 449
Total Molecular Interactions 627
Total Single Events 3978
Pain Genes Associated 46

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular defense response. They are ordered first by their pain relevance and then by number of times they were reported for cellular defense response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16
2 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
3 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
4 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
5 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
6 INT157459 Binding of CX3CR1 and CX3CL1 1 0.32 2.12 1.7
7 INT253863 Binding of LBP and PNP 1 0.13 1.5 1.5
8 INT41591 Binding of PDYN and FAIM3 1 0.00 0 1.41
9 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4
10 INT160589 IL4 Positive_regulation of Gene_expression of OPRM1 1 0.13 0.54 1.35
11 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
12 INT70028 LTA Regulation of PRF1 1 0.02 1.42 1.21
13 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
14 INT70045 IL12A Regulation of Negative_regulation of PRF1 1 0.04 1.42 1.21
15 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
16 INT70042 LTA Regulation of Negative_regulation of PRF1 1 0.02 1.42 1.21
17 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
18 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
19 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
20 INT70044 IL12A Regulation of PRF1 1 0.04 1.42 1.21
21 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
22 INT88193 Binding of IL2 and IL4 1 0.13 1.7 1.2
23 INT142075 IL4 Negative_regulation of Binding of IDO1 1 0.02 2.07 1.19
24 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
25 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
26 INT100678 IL4 Positive_regulation of STAT6 1 0.49 2.63 1.08
27 INT176474 Binding of CXCR3 and CXCL9 3 0.22 1.9 1.05
28 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04
29 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02
30 INT174468 IL7 Positive_regulation of Gene_expression of IL4 1 0.40 1.88 1.02
31 INT174910 Binding of LBP and IFIH1 1 0.04 1.01 1.01
32 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98
33 INT106248 Binding of CCR5 and YY1 1 0.54 0.19 0.98
34 INT239539 Binding of CXCR2 and CALCRL 1 0.00 0.38 0.98
35 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95
36 INT182203 Binding of CXCL1 and CXCR2 1 0.14 1.25 0.95
37 INT182207 Binding of CXCR2 and CXCL13 1 0.42 1.26 0.95
38 INT182208 Binding of CXCR2 and CXCL12 1 0.29 1.26 0.95
39 INT182193 Binding of CXCR2 and CXCL5 1 0.30 1.25 0.94
40 INT182197 Binding of CXCR2 and CCL16 1 0.00 1.24 0.94
41 INT216736 Binding of ADORA2B and ATP6V0A1 2 0.08 0.06 0.93
42 INT128652 ITIH4 Regulation of Gene_expression of CCR5 1 0.36 1.46 0.93
43 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
44 INT128655 ITIH4 Regulation of Gene_expression of CCR3 1 0.36 1.45 0.92
45 INT133073 IL4 Positive_regulation of Phosphorylation of STAT6 1 0.39 0 0.9
46 INT210789 Bst2 Positive_regulation of B2m 1 0.32 0.54 0.89
47 INT62956 CXCR2 Positive_regulation of IL8 1 0.30 0 0.88
48 INT73492 PTGER2 Positive_regulation of Gene_expression of IL4 1 0.08 1.11 0.87
49 INT201945 Binding of CXCR1 and CXCR2 3 0.14 0.84 0.8
50 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79
51 INT183698 Binding of Cxcr2 and Cxcl1 3 0.33 3.26 0.76
52 INT209882 IL4 Positive_regulation of Gene_expression of TNFRSF11A 1 0.11 1.82 0.76
53 INT312691 CCR6 Regulation of PCA 1 0.20 2.76 0.74
54 INT312692 CCR6 Regulation of CCL20 1 0.29 2.42 0.73
55 INT266769 IL2 Positive_regulation of Localization of IL4 1 0.00 1.03 0.72
56 INT182202 Binding of CXCR2 and CXCR4 1 0.31 1.15 0.72
57 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
58 INT83957 Binding of Cxcr2 and Cxcl2 1 0.33 0.97 0.7
59 INT172143 IL4 Positive_regulation of Protein_catabolism of TNF 2 0.11 1.7 0.69
60 INT209859 IL4 Positive_regulation of PPARA 1 0.22 1.66 0.69
61 INT172132 IL4 Positive_regulation of Protein_catabolism of IL1B 2 0.02 1.69 0.68
62 INT190177 Gene_expression of IL13 Regulation of Gene_expression of IL4 1 0.04 0.05 0.68
63 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68
64 INT190171 Gene_expression of IL4 Regulation of Gene_expression of IL13 1 0.04 0.05 0.68
65 INT190164 Gene_expression of IL4 Regulation of MMP12 1 0.11 0.05 0.68
66 INT230336 IL4 Regulation of IL5 2 0.04 0.82 0.67
67 INT318738 Binding of CXCR2 and CXCL6 1 0.32 1.39 0.67
68 INT312688 PCA Regulation of Localization of CCR6 1 0.20 2.67 0.67
69 INT231533 IL4 Positive_regulation of LRP5 1 0.00 0.87 0.67
70 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66
71 INT209854 IL4 Positive_regulation of Gene_expression of CD36 1 0.51 1.2 0.65
72 INT106247 Binding of CCR5 and CCL4 1 0.54 0.06 0.64
73 INT142076 IL4 Negative_regulation of Gene_expression of IFNG 1 0.01 1.58 0.64
74 INT281130 Ccl2 Regulation of Gene_expression of Ccr2 1 0.04 1.09 0.64
75 INT281134 Ccl2 Positive_regulation of Gene_expression of Ccr2 1 0.08 1.09 0.64
76 INT281122 Ccl2 Regulation of Ccr2 1 0.04 1.09 0.63
77 INT172139 IL4 Negative_regulation of IL1B 1 0.02 0.85 0.63
78 INT94075 ARSA Negative_regulation of Gene_expression of IL4 1 0.28 0.26 0.62
79 INT190170 IL4 Regulation of Gene_expression of IL13 1 0.04 0 0.62
80 INT190175 IL13 Regulation of Gene_expression of IL4 1 0.04 0 0.62
81 INT190180 IL4 Regulation of MMP12 1 0.11 0 0.6
82 INT174504 Binding of HLA-B and KIR3DL2 2 0.24 1.69 0.59
83 INT174452 Binding of Cxcr2 and Cxcr3 1 0.31 1.23 0.58
84 INT62034 POMC Regulation of Positive_regulation of IL4 1 0.44 0 0.58
85 INT172144 IL4 Negative_regulation of Transcription of PLA2G4A 1 0.02 0.82 0.58
86 INT172133 IL4 Negative_regulation of Gene_expression of HMOX2 1 0.00 0.81 0.58
87 INT222252 Positive_regulation of Binding of Ccr2 and Fig4 1 0.16 0.67 0.55
88 INT222246 Binding of Ccr2 and Tcf21 1 0.29 0.67 0.55
89 INT222249 Positive_regulation of Binding of Ccr2 and Tcf21 1 0.39 0.67 0.55
90 INT222245 Binding of Ccr2 and Fig4 1 0.12 0.67 0.55
91 INT243056 Binding of LBP and Tlr4 1 0.00 1.11 0.55
92 INT137162 IFNG Positive_regulation of Gene_expression of CXCL9 1 0.45 0.62 0.54
93 INT137157 TNF Positive_regulation of Gene_expression of CXCL9 1 0.38 0.61 0.54
94 INT226360 IL18 Positive_regulation of Gene_expression of IL4 1 0.05 2.66 0.54
95 INT312693 Binding of CCR6 and CCL20 2 0.34 2.33 0.53
96 INT328058 IL4 Positive_regulation of FAAH 1 0.29 4.29 0.53
97 INT349636 IL17A Positive_regulation of Gene_expression of IL4 1 0.06 1.28 0.5
98 INT306019 Binding of Tlr4 and LY96 1 0.06 0.91 0.49
99 INT327806 Binding of ADORA1 and ADORA2A 1 0.06 0.18 0.49
100 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47
101 INT113573 Binding of DMRT1 and FAIM3 1 0.04 0 0.47
102 INT323905 Positive_regulation of CNDP1 Positive_regulation of IL4 1 0.00 0.9 0.46
103 INT323904 CNDP1 Positive_regulation of IL4 1 0.00 0.9 0.46
104 INT176469 Binding of CXCL10 and CXCL9 1 0.01 0.84 0.46
105 INT99789 Cxcl10 Positive_regulation of Cxcr2 1 0.53 0.28 0.46
106 INT72087 IL4 Positive_regulation of POMC 1 0.16 0 0.46
107 INT99790 Ifng Positive_regulation of Cxcr2 1 0.12 0.28 0.46
108 INT323907 ACCS Positive_regulation of IL4 1 0.04 0.9 0.45
109 INT178664 Binding of CCR5 and TH1L 1 0.04 1.04 0.44
110 INT281126 Binding of Ccr2 and Cxcr4 1 0.30 0.32 0.44
111 INT253996 Binding of Cxcr2 and Cxcr4 1 0.18 0.81 0.44
112 INT188564 IRF6 Positive_regulation of Gene_expression of PRF1 1 0.01 0.44 0.44
113 INT352972 IL4 Negative_regulation of Gene_expression of IL8 1 0.07 1.01 0.43
114 INT188562 IRF6 Regulation of Gene_expression of PRF1 1 0.01 0.7 0.43
115 INT352985 IL4 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43
116 INT292634 IL4 Positive_regulation of Gene_expression of FOXP3 1 0.10 0.42 0.43
117 INT181448 Eae1 Positive_regulation of Gene_expression of Ccr2 1 0.04 4.98 0.42
118 INT303858 DDR1 Positive_regulation of CXCR2 1 0.11 1.5 0.42
119 INT292627 IL21 Positive_regulation of IL4 1 0.10 0.41 0.42
120 INT107704 IL1B Positive_regulation of Localization of RELA 1 0.02 0.13 0.41
121 INT299789 IL4 Negative_regulation of Gene_expression of RAE1 1 0.00 0.84 0.41
122 INT328935 Binding of HLA-G and KIR2DS4 1 0.39 0.75 0.41
123 INT334025 Binding of CCR9 and Ccl25 1 0.40 0.96 0.4
124 INT343844 Binding of IRF6 and LY96 1 0.01 1.03 0.4
125 INT352970 IL4 Negative_regulation of Positive_regulation of TH1L 1 0.01 0.91 0.4
126 INT187149 Positive_regulation of Binding of CXCR3 and CXCL9 1 0.29 0.56 0.4
127 INT299786 IL4 Negative_regulation of Gene_expression of CD5 1 0.07 0.82 0.4
128 INT334009 Binding of CCL25 and CCR9 1 0.40 0.96 0.4
129 INT329799 Binding of CD14 and LY96 2 0.04 1.02 0.39
130 INT292887 IL4 Regulation of IL12A 1 0.01 0.25 0.39
131 INT292892 IL4 Regulation of IL8 1 0.01 0.25 0.39
132 INT216737 Binding of ADORA2B and TCFL5 1 0.03 0.05 0.39
133 INT228739 Il4 Positive_regulation of Gene_expression of Ccl17 1 0.14 0.66 0.39
134 INT228761 Tnf Positive_regulation of Gene_expression of Ccl17 1 0.20 0.66 0.39
135 INT330516 Binding of CD8A and CCR6 1 0.07 0.99 0.38
136 INT144047 IL4 Positive_regulation of PTGES 1 0.29 0.43 0.37
137 INT299790 IL4 Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37
138 INT292622 IL6 Positive_regulation of IL4 1 0.02 0.36 0.36
139 INT163909 CCL2 Positive_regulation of Positive_regulation of Ccr2 1 0.05 0.19 0.36
140 INT306254 Binding of TLR2 and LY96 1 0.25 1.29 0.36
141 INT188563 TLR4 Positive_regulation of Gene_expression of PRF1 1 0.03 0.78 0.36
142 INT178662 IFN1@ Positive_regulation of CXCL9 1 0.20 0.5 0.36
143 INT163906 CCL2 Positive_regulation of CCR2 1 0.18 0.2 0.35
144 INT144050 IL4 Negative_regulation of Gene_expression of PTGES 1 0.27 0.48 0.35
145 INT163908 CCL2 Positive_regulation of Ccr2 1 0.05 0.2 0.35
146 INT343857 Binding of ABCC8 and LY96 1 0.02 0.96 0.34
147 INT117589 Binding of C5AR1 and GIPC1 1 0.10 0.39 0.34
148 INT239540 Binding of CXCR2 and MYC 1 0.15 0.09 0.33
149 INT98292 IL4 Regulation of Transcription of OPRM1 1 0.05 0 0.33
150 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33
151 INT98291 FAIM3 Regulation of IL4 1 0.02 0 0.32
152 INT204091 Binding of HLA-G and KIR2DL1 1 0.15 0.86 0.32
153 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32
154 INT244234 Cxcr2 Positive_regulation of Cxcr1 1 0.16 0.08 0.32
155 INT266805 Hand2 Regulation of Gene_expression of IL4 1 0.00 1.23 0.32
156 INT137170 CXCL9 Positive_regulation of Binding of CXCR3 1 0.44 0.31 0.31
157 INT94073 ARSA Negative_regulation of Transcription of IL4 1 0.20 0.16 0.31
158 INT285077 CCL16 Positive_regulation of ITK 1 0.05 1.95 0.31
159 INT174464 IL7 Positive_regulation of IL4 1 0.40 0.61 0.31
160 INT239558 Binding of CXCR2 and Hopx 1 0.06 0.44 0.31
161 INT100684 IL13 Positive_regulation of Positive_regulation of IL4 1 0.18 0.74 0.3
162 INT100675 IL13 Positive_regulation of IL4 1 0.18 0.73 0.3
163 INT117588 Binding of C5AR1 and EDNRA 1 0.40 0.38 0.3
164 INT239537 CXCR2 Regulation of MYC 1 0.15 0.05 0.29
165 INT334499 Binding of AMELX and IL4 1 0.12 0.47 0.29
166 INT98293 IL4 Positive_regulation of Transcription of FAIM3 1 0.02 0 0.29
167 INT219206 CD19 Positive_regulation of Positive_regulation of NCAM1 1 0.30 0 0.29
168 INT219208 CD19 Positive_regulation of Positive_regulation of FCGR3B 1 0.24 0 0.29
169 INT171723 IL4 Positive_regulation of Positive_regulation of TNF 1 0.01 0.67 0.28
170 INT129291 Positive_regulation of OPRM1 Positive_regulation of Phosphorylation of RELA 1 0.06 0.27 0.28
171 INT230342 IL6 Regulation of IL4 1 0.02 0.57 0.28
172 INT171720 IL4 Positive_regulation of Positive_regulation of IFNG 1 0.01 0.67 0.28
173 INT306107 Binding of CCL2 and Ccr2 1 0.06 0 0.28
174 INT230338 IL1B Regulation of IL4 1 0.02 0.57 0.28
175 INT171722 IL4 Positive_regulation of Positive_regulation of CXCL10 1 0.04 0.67 0.28
176 INT171721 IL4 Positive_regulation of Positive_regulation of CXCL9 1 0.04 0.67 0.28
177 INT171724 TNF Positive_regulation of CXCL9 1 0.03 0.6 0.27
178 INT267628 IL4 Positive_regulation of IgG 1 0.00 1.42 0.27
179 INT137166 IL8 Positive_regulation of CXCR2 1 0.24 0.28 0.27
180 INT100683 Negative_regulation of IL4 Positive_regulation of STAT6 1 0.30 0.65 0.27
181 INT100676 IL4 Positive_regulation of Positive_regulation of STAT6 1 0.35 0.68 0.27
182 INT267586 IL4 Positive_regulation of IGHE 1 0.00 1.42 0.27
183 INT171725 IFNG Positive_regulation of CXCL9 1 0.02 0.6 0.27
184 INT132801 IL4 Positive_regulation of Localization of IL6 2 0.26 1.47 0.26
185 INT100679 IL4 Positive_regulation of Gene_expression of FCER2 1 0.34 0.61 0.26
186 INT174506 Binding of HLA-B and HLA-G 1 0.01 0.41 0.26
187 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26
188 INT177961 Binding of CCR3 and CCL11 1 0.04 0.73 0.26
189 INT209884 Binding of IL4 and TNF 1 0.04 0.73 0.26
190 INT100680 IL4 Positive_regulation of SRC 1 0.42 0.66 0.26
191 INT225652 Gene_expression of IL4 Positive_regulation of Positive_regulation of IL12A 1 0.06 1.2 0.25
192 INT354393 NCR1 Regulation of Localization of UNK 1 0.17 0 0.25
193 INT80282 IL4 Positive_regulation of Gene_expression of CCL13 1 0.35 0.39 0.24
194 INT80290 IL4 Positive_regulation of CCL7 1 0.11 0.39 0.24
195 INT80291 IL4 Positive_regulation of CCL13 1 0.10 0.39 0.24
196 INT339287 Binding of Cxcr2 and Cxcl1 1 0.29 0.48 0.24
197 INT202016 Binding of LILRB2 and MRAP 1 0.14 0.38 0.23
198 INT329432 Binding of CCR6 and TH 1 0.00 0.47 0.23
199 INT189150 IL4 Positive_regulation of CSF2 1 0.02 0.09 0.23
200 INT80292 IL4 Positive_regulation of Gene_expression of CCL11 1 0.05 0.37 0.23

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular defense response. They are ordered first by their pain relevance and then by number of times they were reported in cellular defense response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92
2 INT9664 Binding of LBP 127 0.48 94.9 63.42
3 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84
4 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23
5 INT88046 Gene_expression of Ccr2 38 0.76 33.76 28.07
6 INT78251 Positive_regulation of LBP 38 0.69 39.98 26.73
7 INT9088 Negative_regulation of LBP 48 0.58 33.06 25.89
8 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39
9 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81
10 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65
11 INT182217 Gene_expression of CCR9 8 0.75 44.81 18.15
12 INT28642 Gene_expression of CXCR2 60 0.78 38.69 18.11
13 INT116978 Gene_expression of CCR6 53 0.78 56 17.73
14 INT23784 Gene_expression of FAIM3 25 0.55 2.89 17.14
15 INT151434 Positive_regulation of Ccr2 26 0.68 18.34 16.34
16 INT216751 Gene_expression of ADORA2B 36 0.60 3.42 15.6
17 INT89293 Positive_regulation of Gene_expression of CCR5 29 0.70 22.14 15
18 INT107585 Gene_expression of CCR2 35 0.71 26.44 14.75
19 INT7057 Binding of FAIM3 19 0.48 4.02 13.78
20 INT69158 Localization of IL4 48 0.71 31.3 11.98
21 INT157466 Gene_expression of CX3CR1 14 0.76 20.6 10.76
22 INT62089 Phosphorylation of FAIM3 14 0.63 0.62 10.05
23 INT53590 Gene_expression of PRF1 33 0.58 23.46 10.02
24 INT57000 Localization of LBP 21 0.78 11.01 10.01
25 INT102525 Gene_expression of CCR3 24 0.71 16.19 10
26 INT137181 Gene_expression of CXCL9 25 0.65 13.09 9.56
27 INT161222 Positive_regulation of Ccr2 13 0.55 13.77 8.89
28 INT66213 Localization of RELA 63 0.78 14.71 8.77
29 INT32624 Regulation of LBP 15 0.60 11.48 8.71
30 INT88047 Positive_regulation of Gene_expression of Ccr2 15 0.60 10.5 8.63
31 INT123382 Gene_expression of Cxcr2 12 0.69 4.62 8.62
32 INT89292 Positive_regulation of CCR5 27 0.70 15.12 8.59
33 INT670 Gene_expression of B2m 31 0.66 27.32 8.49
34 INT61628 Negative_regulation of Gene_expression of IL4 31 0.55 20.96 8.18
35 INT11568 Gene_expression of ADORA2A 14 0.73 1.51 7.79
36 INT83954 Binding of Cxcr2 21 0.37 17.27 7.65
37 INT216752 Binding of ADORA2B 17 0.36 0.76 7.36
38 INT83951 Gene_expression of Cxcr2 31 0.71 19.36 7.24
39 INT102548 Negative_regulation of Ccr2 14 0.59 19.84 7.22
40 INT91758 Binding of CCR5 28 0.45 20.16 7.07
41 INT157465 Positive_regulation of Gene_expression of CX3CR1 5 0.49 8.9 6.62
42 INT107315 Negative_regulation of CCR5 22 0.57 13.82 6.11
43 INT56299 Transcription of IL4 15 0.64 10.2 5.44
44 INT77146 Binding of IL4 23 0.36 13.69 5.39
45 INT85671 Positive_regulation of Phosphorylation of FAIM3 3 0.53 0.58 5.35
46 INT171562 Regulation of IL4 19 0.36 12.12 5.33
47 INT137179 Positive_regulation of CXCL9 11 0.65 7.73 5.11
48 INT62958 Positive_regulation of CXCR2 14 0.59 8.61 4.92
49 INT99785 Positive_regulation of Cxcr2 10 0.53 8.03 4.89
50 INT673 Positive_regulation of B2m 24 0.68 24.24 4.82
51 INT12823 Positive_regulation of FAIM3 9 0.64 3.23 4.76
52 INT105403 Positive_regulation of Gene_expression of CCR3 10 0.60 7.99 4.74
53 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
54 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47
55 INT7055 Positive_regulation of Binding of FAIM3 4 0.34 1.22 4.34
56 INT25503 Gene_expression of C5AR1 22 0.75 21.88 4.16
57 INT63481 Gene_expression of FOSL1 11 0.75 1.39 4.01
58 INT161221 Positive_regulation of Positive_regulation of Ccr2 3 0.50 4.55 3.98
59 INT85190 Positive_regulation of FOSL1 5 0.67 4.21 3.97
60 INT64473 Regulation of Gene_expression of IL4 17 0.58 6.61 3.96
61 INT222241 Binding of Ccr2 5 0.42 4.09 3.71
62 INT69155 Positive_regulation of Localization of IL4 13 0.40 10.18 3.56
63 INT216985 Gene_expression of Ccl17 10 0.64 8.74 3.56
64 INT118615 Negative_regulation of IL4 20 0.41 13.79 3.49
65 INT19491 Gene_expression of CD19 44 0.75 28.8 3.47
66 INT73557 Positive_regulation of RELA 57 0.46 8.7 3.43
67 INT43259 Negative_regulation of FAIM3 7 0.43 2.7 3.41
68 INT281144 Regulation of Gene_expression of Ccr2 2 0.44 2.38 3.29
69 INT21678 Negative_regulation of B2m 20 0.55 10.11 3.12
70 INT98702 Positive_regulation of Gene_expression of FAIM3 4 0.31 0.48 3.11
71 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09
72 INT120067 Positive_regulation of Gene_expression of CCR2 10 0.46 5.13 3.02
73 INT62088 Regulation of Phosphorylation of FAIM3 3 0.35 0.1 3
74 INT28640 Positive_regulation of Gene_expression of CXCR2 8 0.69 5.51 2.91
75 INT222237 Negative_regulation of Gene_expression of Ccr2 3 0.37 3.39 2.91
76 INT151436 Regulation of Ccr2 4 0.44 2.81 2.82
77 INT123384 Binding of Cxcr2 4 0.33 1.33 2.81
78 INT162380 Negative_regulation of CXCR2 11 0.57 6.98 2.76
79 INT110233 Regulation of Gene_expression of CCR5 6 0.34 7.14 2.76
80 INT106433 Regulation of CCR5 11 0.59 6.93 2.75
81 INT33219 Positive_regulation of C5AR1 14 0.67 7.75 2.74
82 INT70053 Positive_regulation of Gene_expression of PRF1 2 0.12 3.41 2.73
83 INT45109 Binding of C5AR1 10 0.37 5.77 2.69
84 INT334015 Regulation of CCR9 1 0.44 5.32 2.69
85 INT208588 Binding of CXCR2 11 0.48 6.43 2.68
86 INT157461 Binding of CX3CR1 3 0.36 6.72 2.67
87 INT222226 Negative_regulation of Ccr2 6 0.57 3.69 2.66
88 INT65472 Binding of HLA-G 9 0.36 6.06 2.6
89 INT197030 Gene_expression of Ncf1 16 0.78 11.5 2.58
90 INT70052 Transcription of PRF1 4 0.41 3.1 2.58
91 INT77213 Transcription of ADORA2A 1 0.69 0 2.55
92 INT116973 Negative_regulation of Gene_expression of CCR6 5 0.40 7 2.44
93 INT187163 Positive_regulation of CCR6 5 0.65 9.4 2.42
94 INT121909 Regulation of FAIM3 3 0.22 1.06 2.42
95 INT269719 Positive_regulation of Localization of FAIM3 1 0.17 0.22 2.36
96 INT269718 Localization of FAIM3 1 0.25 0.22 2.35
97 INT334016 Localization of CCR9 1 0.72 4.05 2.33
98 INT113775 Negative_regulation of Gene_expression of CCR5 6 0.43 3.97 2.28
99 INT146504 Regulation of Ccr2 5 0.39 3.58 2.21
100 INT182230 Binding of CCR9 3 0.36 4.32 2.19
101 INT53054 Transcription of FAIM3 4 0.56 0.41 2.14
102 INT312696 Regulation of Gene_expression of CCR6 4 0.57 7.95 2.13
103 INT228889 Protein_catabolism of LBP 4 0.77 5.14 2.13
104 INT334022 Positive_regulation of Gene_expression of CCR9 1 0.67 5.97 2.07
105 INT136119 Regulation of FOSL1 2 0.44 1.4 2.04
106 INT148456 Gene_expression of LY96 7 0.19 4.35 2.02
107 INT123530 Phosphorylation of RELA 9 0.80 3.46 1.99
108 INT209888 Positive_regulation of Gene_expression of CCR6 4 0.47 6.97 1.99
109 INT216848 Gene_expression of TCIRG1 8 0.52 2.59 1.95
110 INT182243 Regulation of CXCR2 4 0.39 2.59 1.94
111 INT157464 Positive_regulation of CX3CR1 2 0.68 2.97 1.92
112 INT166311 Positive_regulation of Gene_expression of LBP 7 0.49 4.15 1.81
113 INT26318 Positive_regulation of CD19 7 0.67 5.61 1.8
114 INT249342 Gene_expression of TYROBP 3 0.73 16.71 1.79
115 INT203541 Regulation of Binding of LBP 1 0.39 1.96 1.79
116 INT181341 Binding of Ccr2 8 0.32 6.47 1.77
117 INT55169 Binding of RELA 40 0.36 4.91 1.74
118 INT85191 Positive_regulation of Gene_expression of FOSL1 5 0.67 0.94 1.74
119 INT108875 Positive_regulation of Localization of RELA 9 0.49 1.43 1.72
120 INT216749 Positive_regulation of ADORA2B 6 0.37 0.89 1.72
121 INT102550 Positive_regulation of Gene_expression of Ccr2 6 0.69 4.53 1.67
122 INT174478 Negative_regulation of Localization of IL4 6 0.34 3.56 1.65
123 INT174656 Binding of NCF1 5 0.37 6.46 1.65
124 INT68999 Binding of FOSL1 1 0.35 0 1.64
125 INT157769 Binding of LY96 8 0.47 2.5 1.59
126 INT100694 Negative_regulation of Positive_regulation of IL4 5 0.34 3.27 1.58
127 INT216847 Transcription of ADORA2B 1 0.51 0.93 1.55
128 INT181373 Negative_regulation of Gene_expression of Ccr2 5 0.59 5.92 1.44
129 INT57973 Positive_regulation of ITGB1 5 0.67 1.23 1.44
130 INT85611 Localization of CD160 1 0.01 0.09 1.41
131 INT116900 Positive_regulation of PRF1 5 0.49 4 1.39
132 INT216850 Binding of TCIRG1 3 0.10 0.44 1.37
133 INT242902 Gene_expression of NCF1 12 0.78 9.34 1.36
134 INT157462 Negative_regulation of Binding of CX3CR1 1 0.42 1.62 1.36
135 INT334014 Regulation of Gene_expression of CCR9 1 0.59 3.07 1.36
136 INT334019 Positive_regulation of CCR9 1 0.45 3 1.33
137 INT110252 Positive_regulation of Gene_expression of RELA 29 0.49 6.36 1.31
138 INT63482 Negative_regulation of Gene_expression of FOSL1 2 0.57 0 1.31
139 INT99788 Regulation of Cxcr2 3 0.41 2.25 1.27
140 INT72099 Positive_regulation of Positive_regulation of IL4 4 0.43 0.71 1.24
141 INT21167 Regulation of NCF1 3 0.15 0.75 1.24
142 INT187156 Binding of CD19 10 0.29 2.05 1.2
143 INT174435 Transcription of Cxcr2 1 0.53 2.16 1.19
144 INT199090 Localization of Ncf1 14 0.41 5.14 1.18
145 INT281139 Phosphorylation of Ccr2 2 0.79 1.2 1.18
146 INT281141 Positive_regulation of Phosphorylation of Ccr2 2 0.49 1.2 1.18
147 INT70055 Negative_regulation of PRF1 1 0.11 1.38 1.17
148 INT11266 Positive_regulation of UMOD 2 0.43 1.25 1.16
149 INT85995 Gene_expression of NCR1 5 0.45 3.39 1.15
150 INT241757 Localization of CCR5 6 0.71 5.7 1.14
151 INT119124 Positive_regulation of ADORA2A 4 0.35 0.96 1.14
152 INT62959 Positive_regulation of CCR2 4 0.61 1.47 1.13
153 INT99779 Positive_regulation of Positive_regulation of Cxcr2 2 0.46 1.62 1.13
154 INT222235 Localization of Ccr2 7 0.73 5.32 1.12
155 INT158242 Negative_regulation of Gene_expression of CCR2 3 0.37 2.13 1.12
156 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12
157 INT216849 Binding of ADORA2A 2 0.05 0 1.11
158 INT128970 Localization of Ncf1 6 0.68 4.25 1.1
159 INT147336 Gene_expression of HLA-G 12 0.75 7.27 1.08
160 INT151435 Negative_regulation of Positive_regulation of Ccr2 1 0.53 0.7 1.08
161 INT226434 Positive_regulation of CCR3 8 0.35 4.87 1.07
162 INT194657 Negative_regulation of CCR2 2 0.29 2.3 1.07
163 INT137175 Positive_regulation of Gene_expression of CXCL9 1 0.47 1.32 1.07
164 INT150854 Negative_regulation of Cxcr2 7 0.54 4.12 1.06
165 INT17692 Negative_regulation of C5AR1 5 0.57 2.99 1.04
166 INT119125 Regulation of ADORA2A 2 0.31 0 1.01
167 INT96688 Negative_regulation of Binding of FAIM3 2 0.13 0.09 0.99
168 INT116977 Transcription of CCR6 2 0.50 3.98 0.97
169 INT158064 Negative_regulation of Gene_expression of LBP 1 0.41 1.54 0.97
170 INT109470 Negative_regulation of ITK 3 0.24 2.13 0.96
171 INT672 Positive_regulation of Gene_expression of B2m 2 0.44 1.95 0.96
172 INT341431 Regulation of Positive_regulation of LBP 1 0.24 1.14 0.96
173 INT116976 Localization of CCR6 2 0.73 4.1 0.94
174 INT228729 Negative_regulation of Gene_expression of Ccl17 2 0.48 1.55 0.93
175 INT334017 Regulation of Negative_regulation of CCR9 1 0.44 2.38 0.93
176 INT136118 Regulation of Gene_expression of FOSL1 1 0.26 0.57 0.93
177 INT160599 Regulation of Gene_expression of LBP 2 0.44 1.23 0.92
178 INT153292 Localization of C5AR1 2 0.68 0.79 0.91
179 INT77215 Localization of ADORA2A 2 0.77 0 0.91
180 INT182220 Regulation of Positive_regulation of CXCR2 2 0.39 1.29 0.91
181 INT28641 Regulation of Gene_expression of CXCR2 1 0.45 1.9 0.91
182 INT267894 Gene_expression of ITK 13 0.57 9.71 0.9
183 INT220161 Negative_regulation of Binding of LBP 2 0.43 1.35 0.87
184 INT134099 Negative_regulation of Gene_expression of CXCR2 1 0.04 0.81 0.87
185 INT113672 Positive_regulation of Gene_expression of ITGB1 3 0.49 1.4 0.86
186 INT334020 Negative_regulation of CCR9 1 0.41 2.22 0.86
187 INT328959 Localization of HLA-G 3 0.73 2.22 0.83
188 INT174431 Positive_regulation of Transcription of Cxcr2 1 0.36 1.44 0.83
189 INT59884 Gene_expression of UMOD 4 0.78 2.32 0.82
190 INT174416 Negative_regulation of Gene_expression of Cxcr2 2 0.33 2.06 0.82
191 INT203739 Negative_regulation of NCF1 2 0.27 1.22 0.82
192 INT351306 Positive_regulation of Localization of LBP 1 0.47 1.82 0.82
193 INT154792 Regulation of Regulation of LBP 1 0.26 0.5 0.81
194 INT161223 Negative_regulation of Positive_regulation of Ccr2 1 0.43 0.83 0.81
195 INT154793 Regulation of Localization of LBP 1 0.44 0.5 0.81
196 INT18129 Regulation of Positive_regulation of FAIM3 1 0.00 0.27 0.8
197 INT197032 Regulation of Ncf1 3 0.45 2.84 0.79
198 INT177965 Negative_regulation of Transcription of IL4 3 0.25 2.11 0.78
199 INT87133 Negative_regulation of Positive_regulation of FOSL1 2 0.57 0.82 0.76
200 INT148839 Regulation of Gene_expression of CCR2 2 0.26 1.78 0.76
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