GO:0006972

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Name hyperosmotic response
Categary Process
Go Slim No
Go Link GO:0006972
Unique Molecular Interactions 321
Total Molecular Interactions 415
Total Single Events 4100
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hyperosmotic response. They are ordered first by their pain relevance and then by number of times they were reported for hyperosmotic response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
2 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
3 INT30424 Penk Regulation of Localization of Sst 1 0.20 0 3.1
4 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58
5 INT107812 Nppa Positive_regulation of Localization of Sst 1 0.48 0.54 2.51
6 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
7 INT3576 Sst Negative_regulation of Localization of Gh1 6 0.23 0 2.13
8 INT18593 Binding of Sst and Fdft1 2 0.11 0.08 2.12
9 INT18355 Penk Positive_regulation of Localization of Sst 1 0.31 0 2.04
10 INT13430 Abat Positive_regulation of Localization of Sst 2 0.33 0 1.94
11 INT13979 Gast Positive_regulation of Localization of Sst 3 0.69 0.05 1.75
12 INT31534 Binding of Sst and Oprl1 2 0.16 0.53 1.74
13 INT18592 Sst Regulation of Localization of Acot1 2 0.22 0 1.61
14 INT107815 Gene_expression of Sst Positive_regulation of Localization of Nppa 1 0.52 0.27 1.57
15 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
16 INT7797 Akr1d1 Regulation of Sst 1 0.02 0 1.54
17 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
18 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
19 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53
20 INT107813 Sst Negative_regulation of Localization of Nppa 1 0.44 0.2 1.46
21 INT12691 SST Negative_regulation of Localization of POMC 3 0.24 1.24 1.45
22 INT19013 Ghsr Negative_regulation of Localization of Sst 1 0.15 0 1.44
23 INT79745 Gtf3a Positive_regulation of Positive_regulation of Sst 1 0.09 0 1.4
24 INT26812 SST Regulation of Localization of OXT 1 0.40 0.57 1.37
25 INT18589 Gast Regulation of Localization of Sst 1 0.61 0.15 1.37
26 INT96707 Ntf3 Positive_regulation of Localization of SST 1 0.01 0 1.3
27 INT96708 Bdnf Positive_regulation of Localization of SST 1 0.01 0 1.3
28 INT138211 Mzb1 Regulation of Sst 1 0.05 0.41 1.29
29 INT138212 Mzb1 Regulation of Localization of Sst 1 0.12 0.41 1.29
30 INT7284 Abat Regulation of Sst 1 0.18 0 1.28
31 INT30744 Sst Regulation of Cck 1 0.28 0.43 1.27
32 INT239640 Sst Positive_regulation of Ltp 1 0.04 0.23 1.26
33 INT3575 Sst Regulation of Localization of Gnrhr 2 0.24 0 1.24
34 INT247924 Slc12a5 Regulation of Gene_expression of Slc12a2 1 0.25 1.43 1.23
35 INT247925 Slc12a2 Regulation of Cl 1 0.01 1.44 1.23
36 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
37 INT30871 Abat Regulation of Localization of Sst 1 0.13 0 1.17
38 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13
39 INT68154 Mthfs Positive_regulation of Pdpk1 1 0.01 0.63 1.12
40 INT68158 Pla2g1b Positive_regulation of Pdpk1 1 0.05 0.63 1.12
41 INT68159 Pla2g1b Positive_regulation of Positive_regulation of Pdpk1 1 0.05 0.64 1.12
42 INT68163 Mthfs Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.12
43 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12
44 INT60133 MME Negative_regulation of SST 1 0.10 0 1.12
45 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
46 INT4753 Sst Negative_regulation of Localization of Calca 1 0.39 0.06 1.1
47 INT30575 SST Negative_regulation of Localization of Pomc 1 0.00 0.71 1.06
48 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04
49 INT40715 Binding of SST and Penk 1 0.10 0 1.02
50 INT30378 Binding of Sst and Penk 1 0.28 0.52 1.01
51 INT51261 Calca Negative_regulation of Sst 1 0.20 0.08 1.01
52 INT52435 Positive_regulation of Binding of Sst and Fdft1 1 0.09 0.08 0.98
53 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
54 INT7283 Binding of Sst and Abat 1 0.23 0 0.96
55 INT18597 Sst Positive_regulation of Localization of Acot1 1 0.29 0 0.96
56 INT163265 Sst Negative_regulation of Tyr 1 0.00 0.22 0.95
57 INT30855 Sst Negative_regulation of Localization of Sct 1 0.08 0 0.94
58 INT107335 Pdpk1 Positive_regulation of Regulation of Sigmar1 1 0.02 0 0.93
59 INT53152 Rac1 Regulation of Scg2 1 0.03 0 0.9
60 INT7793 Ptgdr Regulation of Sst 1 0.09 0 0.89
61 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
62 INT48463 Bdnf Positive_regulation of Gene_expression of Sst 1 0.25 0 0.88
63 INT30425 Penk Regulation of Sst 1 0.20 0 0.84
64 INT41156 Sst Negative_regulation of Npr1 1 0.05 0 0.84
65 INT2881 SST Negative_regulation of Positive_regulation of CCK 1 0.32 0.1 0.84
66 INT2880 SST Negative_regulation of CCK 1 0.32 0.1 0.84
67 INT84087 B3GAT1 Positive_regulation of Localization of SST 1 0.06 0 0.83
68 INT69084 Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.08 0.83
69 INT74383 Sst Positive_regulation of GEM 1 0.01 0.09 0.82
70 INT74382 Negative_regulation of Sst Positive_regulation of GEM 1 0.00 0.09 0.82
71 INT303656 SST Negative_regulation of Localization of GAST 1 0.12 1.45 0.82
72 INT74384 Regulation of Sst Positive_regulation of GEM 1 0.00 0.09 0.82
73 INT54260 SST Regulation of GH1 1 0.18 0.06 0.81
74 INT13427 Positive_regulation of Abat Positive_regulation of Localization of Sst 1 0.33 0 0.79
75 INT79743 Nts Positive_regulation of Positive_regulation of Sst 1 0.25 0 0.79
76 INT79742 Positive_regulation of Nts Positive_regulation of Sst 1 0.25 0 0.79
77 INT239638 Sst Regulation of Fig4 1 0.12 0.39 0.78
78 INT79741 Nts Positive_regulation of Sst 1 0.25 0 0.78
79 INT107810 Sst Positive_regulation of Localization of Nppa 1 0.42 0.14 0.77
80 INT18402 Glp1r Regulation of Localization of Sst 1 0.19 0 0.77
81 INT244396 Binding of Cl and Slc12a2 1 0.03 0.88 0.76
82 INT40707 Sst Positive_regulation of Localization of Gnrhr 1 0.26 0 0.76
83 INT54802 SST Negative_regulation of Localization of Gh 1 0.01 0 0.75
84 INT54801 SST Negative_regulation of Positive_regulation of Gh 1 0.01 0 0.75
85 INT41166 Gtf3a Regulation of Localization of SST 1 0.00 0.16 0.74
86 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
87 INT41164 Binding of INS and SST 1 0.07 0.14 0.73
88 INT101676 Sst Negative_regulation of Localization of Gcg 1 0.03 0 0.72
89 INT83714 Adarb1 Positive_regulation of Localization of Sst 1 0.00 0.9 0.72
90 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
91 INT30904 SST Negative_regulation of Localization of Gast 2 0.08 0.49 0.71
92 INT82378 Sst Regulation of Localization of Pomc 1 0.23 0.6 0.7
93 INT79744 Gtf3a Positive_regulation of Sst 1 0.09 0 0.7
94 INT207411 Sst Negative_regulation of Gene_expression of Tacr1 1 0.05 0.76 0.69
95 INT5110 Gal Regulation of Localization of Sst 2 0.20 0 0.68
96 INT52570 HTR1D Negative_regulation of Localization of SST 1 0.46 0.07 0.67
97 INT7418 Calca Positive_regulation of Localization of SST 1 0.04 0.19 0.67
98 INT31260 Sst Negative_regulation of Gh1 2 0.11 0 0.66
99 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65
100 INT89757 SST Regulation of Regulation of CCK 1 0.21 0.37 0.64
101 INT6464 Sst Regulation of Negative_regulation of Npr1 1 0.01 0 0.64
102 INT330104 Binding of Sh3rf1 and Rac1 1 0.13 2.41 0.62
103 INT30902 GCG Positive_regulation of Localization of SST 1 0.11 0.05 0.62
104 INT15731 SST Regulation of Gh 1 0.04 0 0.62
105 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
106 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61
107 INT26997 SST Positive_regulation of Negative_regulation of Gnrhr 1 0.00 0.08 0.59
108 INT41935 SST Negative_regulation of Localization of Nts 1 0.03 0 0.59
109 INT30742 Cck Regulation of Sst 1 0.10 0 0.59
110 INT41542 Pomc Regulation of Sst 1 0.03 0 0.58
111 INT91393 Crh Positive_regulation of SST 1 0.01 0.73 0.58
112 INT303652 Binding of SST and SSTR2 1 0.26 0.46 0.57
113 INT18405 GHRH Positive_regulation of Regulation of SST 1 0.56 0 0.57
114 INT303654 Binding of SST and SSTR5 1 0.22 0.46 0.57
115 INT31214 Sst Negative_regulation of Localization of LH 1 0.15 0 0.56
116 INT31861 Cd79b Regulation of Sst 1 0.49 0.31 0.56
117 INT31862 Pdyn Regulation of Sst 1 0.45 0.31 0.56
118 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 1 0.00 0 0.56
119 INT69826 Binding of SST and TBC1D4 1 0.08 1.49 0.56
120 INT13978 Grpr Positive_regulation of Localization of Sst 1 0.23 0 0.55
121 INT107814 Nppa Positive_regulation of Positive_regulation of Sst 1 0.42 0.16 0.55
122 INT31215 Sst Negative_regulation of Localization of Pomc 1 0.05 0 0.55
123 INT31212 Sst Negative_regulation of Localization of Prl 1 0.20 0 0.55
124 INT316546 Binding of GH1 and SST 2 0.03 0.55 0.54
125 INT102422 POMC Regulation of Gene_expression of Sst 1 0.14 0.24 0.54
126 INT303653 Binding of DRD2 and SST 1 0.18 0.45 0.54
127 INT108441 Adm Positive_regulation of Sst 1 0.40 0 0.54
128 INT30959 Ghrh Positive_regulation of Localization of SST 1 0.01 0 0.54
129 INT80836 Oxt Regulation of Sst 1 0.07 0 0.53
130 INT7501 Sst Positive_regulation of Gast 1 0.53 0 0.53
131 INT5631 Ubqln1 Positive_regulation of Pdpk1 1 0.05 0 0.53
132 INT48646 Sst Regulation of Tacr1 1 0.03 0.09 0.52
133 INT1006 Sst Negative_regulation of Ggh 1 0.24 0 0.52
134 INT79739 Gtf3a Positive_regulation of Gene_expression of Sst 1 0.09 0 0.52
135 INT79746 Ntf3 Positive_regulation of Gene_expression of Sst 1 0.42 0 0.52
136 INT60658 Grip2 Positive_regulation of Localization of Sst 1 0.04 0 0.51
137 INT97483 ADCYAP1 Positive_regulation of Localization of SST 1 0.04 0 0.5
138 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
139 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
140 INT31818 Negative_regulation of Binding of Sst and Oprm1 1 0.26 0.3 0.48
141 INT31817 Positive_regulation of Binding of Sst and Oprm1 1 0.30 0.3 0.48
142 INT31816 Binding of Sst and Oprm1 1 0.22 0.3 0.48
143 INT131508 Gene_expression of Rac1 Positive_regulation of Trpv1 1 0.42 0.21 0.48
144 INT131503 Gene_expression of Rac1 Positive_regulation of Ngf 1 0.38 0.21 0.48
145 INT96709 Ntf3 Regulation of Localization of SST 1 0.01 0 0.46
146 INT95469 P2ry6 Positive_regulation of Positive_regulation of Pdpk1 1 0.15 0 0.46
147 INT7656 Binding of SST and Gs 1 0.02 0.27 0.46
148 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45
149 INT30412 Sst Regulation of Gene_expression of Gh1 1 0.19 0.06 0.45
150 INT108440 Adm Regulation of Localization of Sst 1 0.41 0 0.45
151 INT30219 Nts Regulation of Localization of SST 1 0.01 0 0.45
152 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
153 INT108907 Sst Negative_regulation of Mcpt2 1 0.39 0.23 0.44
154 INT91087 SST Positive_regulation of Positive_regulation of Prkcg 1 0.29 0.05 0.43
155 INT56723 Sst Negative_regulation of Cck 1 0.48 0 0.43
156 INT15024 Prkcg Regulation of Pdpk1 1 0.09 0 0.43
157 INT30856 Sst Regulation of Localization of Sct 1 0.05 0 0.43
158 INT43502 Sst Regulation of Gnrh1 1 0.11 0 0.43
159 INT151184 Pdpk1 Positive_regulation of Trpv1 1 0.08 0 0.42
160 INT64069 Sst Regulation of Localization of Gh1 1 0.10 0.1 0.42
161 INT3571 Sst Regulation of Negative_regulation of Gh1 1 0.24 0 0.42
162 INT151183 Pdpk1 Positive_regulation of Phosphorylation of Trpv1 1 0.08 0 0.42
163 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
164 INT131505 Rac1 Regulation of Gene_expression of Trpv1 1 0.55 0.39 0.42
165 INT52300 Ucma Regulation of Sst 1 0.13 0 0.41
166 INT124405 Binding of SST and SSTR1 1 0.01 0.5 0.41
167 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
168 INT41612 Tac1 Regulation of Localization of Sst 1 0.02 0 0.39
169 INT236111 Binding of Pdpk1 and Ppara 1 0.26 1.21 0.39
170 INT245503 SST Regulation of Gene_expression of CSF2 1 0.06 0.67 0.39
171 INT105772 SST Negative_regulation of Localization of GH1 1 0.10 0.54 0.38
172 INT40728 SST Regulation of IRG1 1 0.11 0.36 0.38
173 INT105770 SST Negative_regulation of Localization of TRH 1 0.17 0.54 0.38
174 INT13584 ANTXRL Negative_regulation of Sst 1 0.00 0.2 0.38
175 INT13583 ANTXRL Negative_regulation of Positive_regulation of Sst 1 0.00 0.2 0.38
176 INT30353 Binding of PDYN and Sst 1 0.02 0 0.37
177 INT316545 Binding of IGF1 and SST 1 0.06 0.45 0.37
178 INT112617 Pdpk1 Regulation of Il1b 1 0.03 1.11 0.36
179 INT112618 Pdpk1 Regulation of Tnf 1 0.03 1.11 0.36
180 INT84600 Binding of Avp and Aqp2 1 0.17 0 0.35
181 INT7415 Calca Positive_regulation of Positive_regulation of SST 1 0.05 0.1 0.34
182 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
183 INT23566 Sst Negative_regulation of Positive_regulation of Cck 1 0.04 0 0.34
184 INT222721 Binding of HTR1A and Pdpk1 1 0.00 0.35 0.33
185 INT57807 Binding of SST and SCG2 1 0.23 0 0.33
186 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
187 INT134490 Binding of Pomc and Sst 1 0.26 0 0.32
188 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
189 INT24185 Sst Negative_regulation of Penk 1 0.05 0 0.32
190 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31
191 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31
192 INT122311 Sst Regulation of Kcnk3 1 0.14 0.28 0.29
193 INT40152 Sst Regulation of Trh 1 0.22 0 0.29
194 INT89900 SST Positive_regulation of Localization of GH1 1 0.14 0 0.28
195 INT89907 SST Positive_regulation of Localization of POMC 1 0.44 0 0.28
196 INT7404 CALCA Positive_regulation of SST 1 0.00 0.08 0.28
197 INT67193 IL8 Regulation of Localization of SST 1 0.00 0.66 0.28
198 INT293118 Avp Regulation of Aqp2 1 0.04 0.7 0.27
199 INT3572 Sst Negative_regulation of Positive_regulation of Gh1 1 0.32 0 0.27
200 INT137167 Binding of IFNG and TLR3 1 0.24 0.32 0.27

Single Events

The table below shows the top 100 pain related interactions that have been reported for hyperosmotic response. They are ordered first by their pain relevance and then by number of times they were reported in hyperosmotic response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1005 Localization of Sst 385 0.81 26.31 244.56
2 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37
3 INT397 Localization of SST 232 0.81 58.05 101.19
4 INT1004 Regulation of Sst 140 0.62 18.52 94.84
5 INT4631 Positive_regulation of Sst 127 0.70 17.37 83.29
6 INT2155 Negative_regulation of Sst 111 0.59 16.58 77.74
7 INT8347 Gene_expression of SST 181 0.78 104.59 65.45
8 INT7280 Positive_regulation of Localization of Sst 97 0.70 5.64 63.37
9 INT5118 Regulation of SST 97 0.62 34.35 51.74
10 INT5098 Negative_regulation of Localization of Sst 70 0.58 3.56 51.17
11 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17
12 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95
13 INT7282 Regulation of Localization of Sst 58 0.62 1.92 34.83
14 INT692 Negative_regulation of SST 72 0.59 28.68 34.52
15 INT691 Binding of SST 67 0.48 24.66 32.67
16 INT19396 Regulation of Rac1 66 0.53 37.41 30.01
17 INT7412 Positive_regulation of SST 71 0.70 24.44 29.48
18 INT7281 Binding of Sst 42 0.48 5.48 26.57
19 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33
20 INT693 Negative_regulation of Localization of SST 46 0.59 8.57 21.75
21 INT48769 Regulation of Pdpk1 20 0.35 9.78 20.36
22 INT18457 Transcription of Sst 25 0.69 4.28 18.25
23 INT7414 Regulation of Localization of SST 31 0.60 4.85 17.46
24 INT100115 Gene_expression of Slc12a2 34 0.76 39.15 15.69
25 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1
26 INT7413 Positive_regulation of Localization of SST 37 0.69 5.64 13.94
27 INT26733 Gene_expression of Pdpk1 17 0.48 5.74 13.91
28 INT27627 Binding of Rac1 41 0.41 22.88 13.68
29 INT14098 Regulation of Gene_expression of Sst 13 0.44 4.01 12.92
30 INT91360 Negative_regulation of Slc12a2 16 0.54 10.46 12.89
31 INT5630 Localization of Pdpk1 10 0.45 5.21 11.36
32 INT127009 Positive_regulation of Phosphorylation of Slc12a2 5 0.70 5.3 9.9
33 INT127010 Phosphorylation of Slc12a2 6 0.82 4.68 9.66
34 INT62014 Negative_regulation of Slc12a2 17 0.49 12.85 8.99
35 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98
36 INT138889 Positive_regulation of Slc12a2 23 0.65 18.53 8.85
37 INT14582 Negative_regulation of Negative_regulation of Sst 9 0.56 0.52 8.38
38 INT104013 Negative_regulation of Gene_expression of Pdpk1 4 0.31 2.36 7.89
39 INT18455 Positive_regulation of Gene_expression of Sst 12 0.70 1.55 7.83
40 INT127008 Positive_regulation of Slc12a2 2 0.70 4.73 7.61
41 INT7499 Negative_regulation of Positive_regulation of Sst 9 0.59 0.42 6.9
42 INT71824 Phosphorylation of Pdpk1 14 0.38 4.9 6.86
43 INT94356 Regulation of Slc12a2 11 0.58 12.8 6.59
44 INT24724 Positive_regulation of Gene_expression of SST 11 0.67 7.51 6.12
45 INT55077 Positive_regulation of Positive_regulation of Pdpk1 6 0.26 1.77 5.78
46 INT18401 Positive_regulation of Positive_regulation of Sst 9 0.47 0.29 5.68
47 INT68465 Positive_regulation of Gene_expression of Pdpk1 7 0.19 2.35 5.49
48 INT146488 Gene_expression of Slc12a2 16 0.73 4.63 5.11
49 INT67195 Negative_regulation of Gene_expression of SST 7 0.42 6.98 4.88
50 INT244386 Positive_regulation of Gene_expression of Slc12a2 10 0.58 18.39 4.5
51 INT79738 Regulation of Transcription of Sst 3 0.30 1.56 4.38
52 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33
53 INT7363 Regulation of Binding of Sst 5 0.44 1.5 4.22
54 INT1231 Negative_regulation of Positive_regulation of Pdpk1 6 0.35 1.88 4.13
55 INT14930 Regulation of Gene_expression of SST 12 0.45 6.86 3.89
56 INT18456 Positive_regulation of Transcription of Sst 5 0.49 1.09 3.78
57 INT118644 Regulation of Slc12a2 5 0.45 2.43 3.6
58 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41
59 INT38032 Protein_catabolism of SST 5 0.98 2.23 3.34
60 INT41742 Negative_regulation of Gene_expression of Sst 4 0.43 0.78 3.27
61 INT58475 Localization of Rac1 12 0.75 5.94 3.2
62 INT10265 Regulation of Regulation of Sst 6 0.33 0.35 2.91
63 INT47846 Negative_regulation of Localization of Pdpk1 2 0.33 1.12 2.75
64 INT244385 Phosphorylation of Slc12a2 12 0.77 4.67 2.74
65 INT58751 Positive_regulation of Binding of SST 4 0.70 2.51 2.67
66 INT96763 Positive_regulation of Localization of Pdpk1 1 0.39 2.08 2.65
67 INT138891 Regulation of Gene_expression of Slc12a2 5 0.58 4.83 2.64
68 INT14581 Regulation of Negative_regulation of Sst 4 0.45 0.58 2.6
69 INT84599 Gene_expression of Aqp2 31 0.77 22.58 2.54
70 INT127007 Positive_regulation of Positive_regulation of Slc12a2 2 0.70 1.42 2.46
71 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33
72 INT101631 Phosphorylation of SST 1 0.66 0 2.04
73 INT29120 Negative_regulation of Binding of Sst 2 0.04 0.47 1.97
74 INT117980 Regulation of Rac1 10 0.45 3.72 1.88
75 INT18385 Protein_catabolism of Sst 5 0.75 0.05 1.87
76 INT247918 Positive_regulation of Positive_regulation of Slc12a2 1 0.39 2.55 1.86
77 INT26735 Regulation of Gene_expression of Pdpk1 2 0.24 0.56 1.84
78 INT84595 Negative_regulation of Aqp2 11 0.58 4.88 1.78
79 INT210693 Positive_regulation of Gene_expression of Slc12a2 5 0.46 1.3 1.77
80 INT104014 Negative_regulation of Phosphorylation of Pdpk1 2 0.23 0.59 1.72
81 INT30573 Regulation of Regulation of SST 2 0.18 1.55 1.69
82 INT244392 Binding of Slc12a2 3 0.35 2.05 1.68
83 INT14254 Positive_regulation of Regulation of Sst 2 0.50 0.23 1.53
84 INT101632 Positive_regulation of Phosphorylation of SST 1 0.40 0 1.52
85 INT117710 Binding of Slc12a2 4 0.19 0.13 1.48
86 INT60137 Negative_regulation of Protein_catabolism of SST 2 0.17 0.93 1.43
87 INT19892 Negative_regulation of Negative_regulation of SST 1 0.41 0.57 1.43
88 INT67464 Positive_regulation of Negative_regulation of Pdpk1 1 0.19 0.15 1.41
89 INT118927 Positive_regulation of Phosphorylation of Pdpk1 2 0.04 0.76 1.38
90 INT186810 Positive_regulation of TLR3 13 0.65 6.37 1.37
91 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
92 INT7400 Negative_regulation of Regulation of Sst 2 0.41 0.16 1.27
93 INT221206 Phosphorylation of Pdpk1 3 0.53 0.13 1.25
94 INT18370 Regulation of Positive_regulation of Sst 2 0.20 0.07 1.24
95 INT16013 Gene_expression of Rac1 52 0.75 23.79 1.21
96 INT100328 Gene_expression of AQP2 6 0.75 2.41 1.21
97 INT98062 Regulation of Gene_expression of Rac1 4 0.39 1.41 1.21
98 INT104011 Transcription of Pdpk1 1 0.28 0 1.2
99 INT104012 Regulation of Transcription of Pdpk1 1 0.14 0 1.2
100 INT26734 Binding of Pdpk1 4 0.29 1.01 1.19
101 INT79557 Localization of Aqp2 5 0.73 2 1.13
102 INT98061 Negative_regulation of Binding of Rac1 3 0.43 2.28 1.13
103 INT244393 Positive_regulation of Phosphorylation of Slc12a2 1 0.65 1.92 1.12
104 INT127004 Regulation of Phosphorylation of Slc12a2 1 0.54 0.35 1.1
105 INT186807 Positive_regulation of Gene_expression of TLR3 8 0.53 7.19 1.08
106 INT18408 Positive_regulation of Regulation of SST 2 0.45 0.51 1.05
107 INT9182 Negative_regulation of Positive_regulation of SST 3 0.41 0.15 1.03
108 INT149656 Negative_regulation of Gene_expression of Slc12a2 3 0.38 2.36 1.02
109 INT24761 Positive_regulation of Negative_regulation of SST 2 0.49 0.86 1.01
110 INT67174 Negative_regulation of Rac1 22 0.56 10.72 0.99
111 INT84597 Transcription of Aqp2 3 0.55 2.11 0.98
112 INT160022 Transcription of Slc12a2 2 0.53 0.75 0.97
113 INT68467 Regulation of Regulation of Pdpk1 1 0.05 0.09 0.96
114 INT81211 Transcription of Rac1 4 0.54 1.05 0.89
115 INT84094 Negative_regulation of Regulation of SST 1 0.05 0 0.89
116 INT31334 Positive_regulation of Negative_regulation of Sst 1 0.43 0 0.87
117 INT84598 Regulation of Aqp2 13 0.45 4.28 0.86
118 INT330097 Positive_regulation of Positive_regulation of Rac1 1 0.37 2.47 0.86
119 INT108348 Positive_regulation of Aqp2 10 0.68 4.94 0.82
120 INT186804 Binding of TLR3 14 0.45 8.41 0.79
121 INT264629 Localization of Rac1 8 0.72 5.7 0.79
122 INT149238 Positive_regulation of Gene_expression of Aqp2 5 0.66 3.07 0.73
123 INT241788 Positive_regulation of Gene_expression of AQP2 3 0.67 1.26 0.7
124 INT115596 Regulation of Regulation of Rac1 1 0.36 0.29 0.7
125 INT186798 Regulation of TLR3 5 0.42 3.13 0.69
126 INT31576 Transcription of SST 5 0.69 0.89 0.68
127 INT204525 Negative_regulation of Gene_expression of TLR3 2 0.54 1.8 0.61
128 INT114405 Regulation of Pkn1 1 0.44 1.58 0.61
129 INT84596 Negative_regulation of Gene_expression of Aqp2 3 0.58 8.49 0.6
130 INT31729 Positive_regulation of Positive_regulation of SST 2 0.50 1.03 0.6
131 INT246423 Negative_regulation of TLR3 1 0.40 2.2 0.6
132 INT30629 Regulation of Positive_regulation of SST 2 0.37 1.35 0.59
133 INT84594 Negative_regulation of Transcription of Aqp2 1 0.43 0 0.59
134 INT228103 Positive_regulation of Rac1 25 0.67 18.92 0.57
135 INT79249 Regulation of Negative_regulation of Pdpk1 1 0.03 0.09 0.57
136 INT100322 Localization of AQP2 5 0.80 0.56 0.56
137 INT16012 Binding of Rac1 17 0.37 6.9 0.53
138 INT98037 Negative_regulation of Negative_regulation of Pdpk1 1 0.05 0.26 0.52
139 INT40751 Positive_regulation of Protein_catabolism of Sst 1 0.47 0.05 0.46
140 INT160019 Regulation of Transcription of Slc12a2 1 0.26 0.41 0.46
141 INT81212 Negative_regulation of Transcription of Rac1 1 0.01 0 0.46
142 INT87847 Regulation of Positive_regulation of Rac1 2 0.36 1.49 0.43
143 INT18384 Negative_regulation of Protein_catabolism of Sst 1 0.32 0 0.42
144 INT328606 Regulation of Regulation of Slc12a2 1 0.10 0 0.42
145 INT266810 Negative_regulation of Binding of SST 1 0.22 0.56 0.41
146 INT102722 Phosphorylation of PDPK1 3 0.82 1.39 0.4
147 INT149235 Positive_regulation of Transcription of Aqp2 1 0.45 0.72 0.4
148 INT149244 Positive_regulation of Localization of Aqp2 1 0.49 0.72 0.4
149 INT236107 Binding of Pdpk1 2 0.26 1.38 0.39
150 INT236105 Negative_regulation of Binding of Pdpk1 1 0.30 1.22 0.39
151 INT100324 Regulation of Localization of AQP2 1 0.27 0.19 0.38
152 INT157836 Regulation of Gene_expression of Aqp2 9 0.57 8.37 0.37
153 INT100323 Regulation of Gene_expression of AQP2 1 0.45 0.18 0.36
154 INT179816 Positive_regulation of Pdpk1 4 0.31 0.36 0.35
155 INT246419 Positive_regulation of Negative_regulation of TLR3 1 0.43 0.67 0.34
156 INT124986 Positive_regulation of Localization of Rac1 3 0.50 1.22 0.33
157 INT79558 Binding of Aqp2 2 0.31 0.25 0.33
158 INT100114 Localization of Slc12a2 3 0.73 2.02 0.31
159 INT238439 Positive_regulation of PDPK1 2 0.20 1.3 0.31
160 INT112551 Protein_catabolism of Rac1 2 0.66 0.29 0.3
161 INT244383 Transcription of Slc12a2 2 0.67 0.82 0.29
162 INT116729 Regulation of Localization of Rac1 1 0.01 0.07 0.29
163 INT99682 Phosphorylation of Rac1 1 0.54 0.72 0.28
164 INT101635 Regulation of Binding of SST 1 0.36 0 0.26
165 INT162873 Negative_regulation of Negative_regulation of Rac1 1 0.34 0.35 0.26
166 INT330090 Regulation of Negative_regulation of Rac1 1 0.36 0.53 0.25
167 INT102717 Gene_expression of PDPK1 1 0.77 3.11 0.25
168 INT330093 Negative_regulation of Positive_regulation of Rac1 1 0.34 0.88 0.23
169 INT102719 Negative_regulation of PDPK1 1 0.58 3 0.21
170 INT186803 Transcription of TLR3 6 0.67 1.54 0.2
171 INT244389 Negative_regulation of Positive_regulation of Slc12a2 1 0.40 0.4 0.2
172 INT215814 Negative_regulation of Gene_expression of Aqp1 2 0.31 0.25 0.17
173 INT98625 Regulation of Aqp1 1 0.27 0.1 0.17
174 INT168055 Regulation of Transcription of Rac1 1 0.36 0.34 0.16
175 INT354160 Negative_regulation of Transcription of SST 1 0.09 0.09 0.16
176 INT133599 Positive_regulation of Binding of Rac1 2 0.40 0.4 0.15
177 INT330085 Regulation of Binding of Rac1 1 0.36 0.28 0.15
178 INT102720 Positive_regulation of Gene_expression of PDPK1 1 0.69 1.61 0.13
179 INT186797 Localization of TLR3 2 0.70 2.69 0.12
180 INT236109 Localization of Pdpk1 1 0.49 0.75 0.12
181 INT186809 Positive_regulation of Transcription of TLR3 2 0.65 0.5 0.11
182 INT246420 Regulation of Gene_expression of TLR3 1 0.57 0.79 0.11
183 INT215820 Negative_regulation of Aqp1 3 0.23 0.83 0.1
184 INT302613 Positive_regulation of Gene_expression of Rac1 14 0.67 3.7 0.08
185 INT157832 Phosphorylation of Aqp2 2 0.77 2.04 0.08
186 INT334443 Positive_regulation of Positive_regulation of Rac1 1 0.33 1.1 0.08
187 INT102718 Negative_regulation of Phosphorylation of PDPK1 1 0.43 0.83 0.08
188 INT262510 Regulation of Gene_expression of Aqp1 1 0.33 1.18 0.07
189 INT285436 Negative_regulation of Transcription of TLR3 1 0.24 0.32 0.07
190 INT104656 Regulation of Phosphorylation of Pdpk1 1 0.05 1.74 0.07
191 INT292542 Localization of Slc12a2 1 0.66 0 0.07
192 INT120564 Gene_expression of Pdpk1 2 0.62 1.54 0.06
193 INT302624 Negative_regulation of Gene_expression of Rac1 1 0.56 3.67 0.06
194 INT120565 Positive_regulation of Gene_expression of Pdpk1 1 0.40 1.26 0.06
195 INT293110 Positive_regulation of Phosphorylation of Aqp2 1 0.47 1.39 0.05
196 INT293109 Positive_regulation of Transcription of Slc12a2 1 0.10 0.35 0.05
197 INT323949 Negative_regulation of Positive_regulation of Rac1 1 0.23 0.53 0.05
198 INT334445 Regulation of Positive_regulation of Rac1 1 0.40 1.73 0.04
199 INT236706 Regulation of Pdpk1 1 0.12 0.38 0.04
200 INT302611 Regulation of Gene_expression of Rac1 1 0.43 4.5 0.03
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