GO:0006979

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Name response to oxidative stress
Categary Process
Go Slim No
Go Link GO:0006979
Unique Molecular Interactions 2518
Total Molecular Interactions 3398
Total Single Events 35192
Pain Genes Associated 142

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to oxidative stress. They are ordered first by their pain relevance and then by number of times they were reported for response to oxidative stress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54
2 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
3 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
4 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
5 INT227157 Binding of PEBP1 and Gpm6a 1 0.00 1.28 5.52
6 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
7 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
8 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
9 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
10 INT150632 Ea1 Negative_regulation of Mpo 1 0.17 1.55 2.9
11 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84
12 INT26892 OGG1 Negative_regulation of Gene_expression of Gh1 1 0.12 0 2.53
13 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
14 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37
15 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
16 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
17 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
18 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
19 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06
20 INT88883 IRF6 Positive_regulation of Nfkb1 1 0.11 0.53 2.01
21 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
22 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
23 INT14991 SFTPA1 Positive_regulation of Localization of MPO 1 0.11 1.65 1.92
24 INT243043 Binding of Mmp9 and Timp1 1 0.05 0.25 1.86
25 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
26 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
27 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
28 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
29 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
30 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
31 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
32 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
33 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
34 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
35 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
36 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
37 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
38 INT168611 Binding of Mmp9 and Ndor1 1 0.29 0.41 1.57
39 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
40 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
41 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54
42 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
43 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
44 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
45 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
46 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
47 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
48 INT167169 Nfkb1 Regulation of Gene_expression of Crp 1 0.09 1.76 1.38
49 INT26893 OGG1 Negative_regulation of Gh1 1 0.12 0 1.37
50 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
51 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
52 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
53 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 1 0.01 0.81 1.31
54 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31
55 INT158144 Binding of Gpx1 and Glyat 2 0.31 0 1.29
56 INT276282 Binding of Atrn and Mc1r 1 0.32 0.41 1.29
57 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27
58 INT86518 Ass1 Positive_regulation of Hmox2 1 0.03 0.08 1.27
59 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 1 0.47 0.88 1.26
60 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
61 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
62 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
63 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
64 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
65 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
66 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
67 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2
68 INT187172 RPS3AP9 Negative_regulation of MMP9 1 0.00 0.89 1.2
69 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
70 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
71 INT146352 Binding of Rgs14 and Mors1 1 0.23 0.27 1.17
72 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 1.16
73 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
74 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
75 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
76 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
77 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
78 INT69504 Binding of Nos1 and Gatm 1 0.05 0 1.13
79 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
80 INT160540 Binding of NGF and PSIP1 2 0.29 1.43 1.12
81 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
82 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
83 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
84 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07
85 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
86 INT56990 Cat Regulation of Efs 1 0.26 0 1.05
87 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
88 INT126401 ITIH4 Positive_regulation of Gene_expression of Ptgs2 1 0.00 1.05 1.04
89 INT69011 Binding of Cebpb and Nfkb1 1 0.19 0.75 1.04
90 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
91 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
92 INT88971 Binding of Sult4a1 and Atrn 1 0.02 0.54 1.03
93 INT88881 Negative_regulation of IRF6 Positive_regulation of Nfkb1 1 0.09 0.27 1.03
94 INT160541 Binding of BDNF and PSIP1 4 0.49 1.94 1.02
95 INT74934 Regulation of IRF6 Positive_regulation of Nfkb1 1 0.01 0.52 1.02
96 INT74933 IRF6 Positive_regulation of Nfkb1 1 0.02 0.52 1.01
97 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
98 INT250085 Coq7 Positive_regulation of Ltp 1 0.00 0.52 1
99 INT112163 Calca Positive_regulation of Mpo 1 0.49 1.23 1
100 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
101 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
102 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98
103 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98
104 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
105 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97
106 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
107 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
108 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
109 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97
110 INT155985 Nfkb1 Negative_regulation of Gene_expression of Cyp11a1 1 0.10 0.53 0.95
111 INT130722 Binding of IL1B and Nfkb1 1 0.28 1.23 0.95
112 INT166842 Binding of ANXA1 and Nfkb1 1 0.37 1.64 0.95
113 INT61037 Och Positive_regulation of Ptgs1 1 0.00 0 0.95
114 INT42482 Binding of Cpe and Pebp1 1 0.02 0 0.95
115 INT266659 Binding of MMP9 and MOCS1 1 0.01 1.71 0.94
116 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
117 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
118 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
119 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
120 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
121 INT243044 Mmp8 Regulation of Mmp9 1 0.05 1.45 0.91
122 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
123 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
124 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
125 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
126 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
127 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9
128 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
129 INT119100 Positive_regulation of F2rl1 Positive_regulation of Positive_regulation of Ptgs1 1 0.03 0.56 0.9
130 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
131 INT152702 Nfkb1 Negative_regulation of Ltp 1 0.01 0.15 0.89
132 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
133 INT152700 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
134 INT129034 Nfkbia Positive_regulation of Nfkb1 1 0.02 0.67 0.89
135 INT152701 Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
136 INT108687 Nfkb1 Regulation of Positive_regulation of Nos2 1 0.50 1.28 0.88
137 INT318462 Nnat Positive_regulation of Nfkb1 1 0.46 0.9 0.88
138 INT152694 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
139 INT152697 Nfkb1 Negative_regulation of Ltp 1 0.04 0.15 0.88
140 INT108686 Nfkb1 Regulation of Nos2 1 0.69 1.27 0.88
141 INT152695 Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
142 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
143 INT96811 Nfkb1 Regulation of Gene_expression of IK 1 0.00 1.06 0.87
144 INT251159 Binding of Clu and Positive_regulation of Trpv1 1 0.16 0 0.87
145 INT160412 Tat Positive_regulation of Transcription of Nos2 1 0.37 0.98 0.86
146 INT160413 Tat Positive_regulation of Gene_expression of Cd40lg 1 0.50 0.98 0.86
147 INT116555 Olr1627 Negative_regulation of Positive_regulation of Nfkb1 1 0.02 1.51 0.86
148 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
149 INT116559 Olr1627 Negative_regulation of Regulation of Ptgs2 1 0.01 1.52 0.86
150 INT120293 RYBP Positive_regulation of Abcc2 1 0.04 0.14 0.86
151 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
152 INT146495 Snta1 Positive_regulation of Adrbk1 1 0.14 0.68 0.85
153 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
154 INT116557 Olr1627 Negative_regulation of Localization of Nfkb1 1 0.02 1.51 0.85
155 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
156 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84
157 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
158 INT192158 Binding of Mmp2 and Mmp9 1 0.21 0.94 0.83
159 INT116558 Ptpn5 Positive_regulation of Nfkb1 1 0.46 2.01 0.83
160 INT140004 Srxn1 Negative_regulation of Accn2 1 0.01 0.47 0.83
161 INT309001 Ins1 Positive_regulation of Mmp9 1 0.20 1.96 0.83
162 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
163 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82
164 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
165 INT48751 Binding of Nqo1 and Npy 1 0.28 0 0.82
166 INT88878 Negative_regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.06 0.1 0.81
167 INT164607 Positive_regulation of GSR Positive_regulation of Gpx1 1 0.01 0.33 0.81
168 INT164606 GSR Positive_regulation of Gpx1 1 0.01 0.32 0.8
169 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
170 INT144449 Plscr1 Positive_regulation of Gene_expression of Nqo1 1 0.15 0.18 0.8
171 INT144451 Napa Positive_regulation of Gene_expression of Nqo1 1 0.07 0.18 0.8
172 INT160411 Tat Positive_regulation of Il6 1 0.17 0.89 0.8
173 INT62176 Binding of PTGS2 and Ptgs1 2 0.00 0.69 0.79
174 INT127383 Neo1 Regulation of Localization of Mpo 1 0.14 0.7 0.79
175 INT132889 Nfkb1 Regulation of Gene_expression of Nos2 1 0.16 0.21 0.79
176 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
177 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78
178 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
179 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
180 INT117604 AKR1C1 Negative_regulation of Positive_regulation of Mpo 1 0.00 1.45 0.78
181 INT168457 Sult1a1 Positive_regulation of Cat 1 0.15 1.56 0.78
182 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
183 INT152234 Mapk8 Positive_regulation of Localization of Nfkb1 1 0.33 0.26 0.78
184 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
185 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
186 INT347394 RYBP Positive_regulation of Lpo 1 0.02 0 0.77
187 INT121647 Binding of Oprm1 and Atrn 1 0.01 0.12 0.77
188 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
189 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
190 INT124384 ADRBK1 Negative_regulation of MC1R 1 0.40 0.42 0.77
191 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
192 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
193 INT90118 Jun Regulation of Gene_expression of Nfkb1 1 0.18 0.39 0.76
194 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
195 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
196 INT90125 Nfkb1 Regulation of Gene_expression of Nos1 1 0.17 0.39 0.76
197 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
198 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
199 INT123556 Shfm1 Regulation of Mpo 1 0.09 0.88 0.76
200 INT90116 Nfkb1 Positive_regulation of Gene_expression of Nos1 1 0.32 0.39 0.76

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to oxidative stress. They are ordered first by their pain relevance and then by number of times they were reported in response to oxidative stress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26
2 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85
3 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6
4 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73
5 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
6 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51
7 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06
8 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58
9 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97
10 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47
11 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08
12 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
13 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6
14 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5
15 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
16 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01
17 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73
18 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5
19 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
20 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
21 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04
22 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71
23 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39
24 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41
25 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02
26 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9
27 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57
28 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
29 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46
30 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
31 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94
32 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
33 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33
34 INT99610 Localization of MMP9 126 0.79 48.46 32.67
35 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58
36 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17
37 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
38 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
39 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18
40 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
41 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
42 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02
43 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18
44 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95
45 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31
46 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
47 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
48 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
49 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42
50 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35
51 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85
52 INT9886 Gene_expression of Ptgs1 92 0.77 40.66 25.31
53 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
54 INT58301 Positive_regulation of Mpo 87 0.70 80.19 23.99
55 INT66758 Binding of Nfkb1 97 0.48 50.65 23.65
56 INT134651 Binding of TLR4 89 0.48 66.96 23.19
57 INT71875 Localization of Nfkb1 92 0.78 48.13 22.94
58 INT16721 Negative_regulation of Cat 56 0.59 44.44 22.84
59 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5
60 INT21503 Binding of Ptgs1 45 0.48 15.6 22.29
61 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
62 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
63 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
64 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18
65 INT52529 Regulation of Nfkb1 48 0.61 26.2 20.89
66 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
67 INT69877 Positive_regulation of Positive_regulation of Nfkb1 53 0.68 31.44 20.7
68 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
69 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61
70 INT17848 Binding of PTGS2 70 0.46 32.1 20.6
71 INT45840 Positive_regulation of Gene_expression of Ptgs1 35 0.50 16.07 20.49
72 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42
73 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
74 INT6993 Negative_regulation of Mpo 72 0.59 61.83 19.51
75 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
76 INT61519 Gene_expression of Mpo 112 0.78 89.29 18.22
77 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04
78 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64
79 INT132997 Localization of Mmp9 59 0.80 45.9 17.61
80 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
81 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
82 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15
83 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1
84 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07
85 INT9197 Binding of PTGS1 44 0.48 18.48 16.26
86 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
87 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
88 INT12950 Gene_expression of Cat 85 0.75 35.94 15.76
89 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
90 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
91 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07
92 INT5904 Localization of MPO 62 0.81 36.37 14.64
93 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
94 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
95 INT52696 Positive_regulation of Ptgs2 48 0.70 27.65 14.44
96 INT53080 Positive_regulation of Ptgs1 42 0.42 23.58 14.37
97 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01
98 INT78480 Localization of Nfkb1 39 0.80 23.14 13.64
99 INT71879 Negative_regulation of Localization of Nfkb1 30 0.57 21.8 13.48
100 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34
101 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
102 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
103 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8
104 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39
105 INT4460 Regulation of Mpo 44 0.62 31.16 12.11
106 INT5649 Negative_regulation of Positive_regulation of Mpo 31 0.59 26.62 11.92
107 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9
108 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77
109 INT12992 Negative_regulation of Gene_expression of Ptgs1 33 0.42 20.47 11.77
110 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73
111 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
112 INT65057 Regulation of Nfkb1 28 0.47 16.48 11.62
113 INT20457 Regulation of Ptgs1 23 0.48 11.63 11.56
114 INT787 Localization of Ptgs1 31 0.80 12.36 11.55
115 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39
116 INT143098 Negative_regulation of Gene_expression of Adrbk1 9 0.58 8.51 11.37
117 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28
118 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
119 INT10384 Positive_regulation of Nqo1 62 0.70 14.27 11.08
120 INT81531 Positive_regulation of Gene_expression of Nfkb1 27 0.69 13.9 11.04
121 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92
122 INT83886 Negative_regulation of HMOX2 27 0.43 11.69 10.78
123 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76
124 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
125 INT54706 Regulation of Adrbk1 11 0.62 0.89 10.69
126 INT84077 Gene_expression of Hmox2 18 0.77 6.41 10.66
127 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6
128 INT41627 Gene_expression of Nqo1 33 0.65 4.58 10.48
129 INT53081 Negative_regulation of Gene_expression of Ptgs2 29 0.59 15.83 10.39
130 INT89282 Regulation of MMP9 39 0.60 25.45 10.34
131 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
132 INT79720 Positive_regulation of Cat 57 0.70 31.81 10.11
133 INT65058 Binding of Nfkb1 36 0.45 19.87 10.02
134 INT85535 Negative_regulation of Gene_expression of Ptgs2 27 0.51 16.04 10.01
135 INT113605 Negative_regulation of Gene_expression of Mmp9 25 0.41 22.92 9.98
136 INT14881 Gene_expression of Car3 49 0.73 14.89 9.94
137 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
138 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79
139 INT120509 Gene_expression of Cat 65 0.77 50.9 9.75
140 INT104502 Gene_expression of Abcc2 26 0.78 8.37 9.65
141 INT58986 Gene_expression of Clu 17 0.77 8.35 9.61
142 INT12563 Localization of Mpo 33 0.81 20.99 9.58
143 INT69321 Regulation of Gene_expression of PTGS2 27 0.61 13.27 9.53
144 INT54707 Positive_regulation of Adrbk1 14 0.67 0.51 9.51
145 INT71878 Protein_catabolism of Nfkb1 24 0.65 10.85 9.46
146 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37
147 INT37896 Positive_regulation of Gene_expression of PTGS1 37 0.67 17.28 9.27
148 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25
149 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93
150 INT12991 Negative_regulation of Gene_expression of PTGS1 28 0.41 13.39 8.9
151 INT23264 Negative_regulation of Positive_regulation of Ptgs1 16 0.39 8.47 8.9
152 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83
153 INT52442 Binding of Ptgs1 16 0.35 9.05 8.78
154 INT6573 Regulation of Negative_regulation of Ptgs1 19 0.45 6.16 8.71
155 INT140411 Gene_expression of Nqo1 45 0.60 62.35 8.7
156 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
157 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
158 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
159 INT5194 Positive_regulation of Lpo 63 0.70 26.44 8.37
160 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
161 INT127378 Localization of Mpo 21 0.78 26.36 8.28
162 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
163 INT56223 Positive_regulation of MPO 35 0.70 43 8.2
164 INT82450 Negative_regulation of Hmox1 33 0.55 19.07 8.12
165 INT135443 Phosphorylation of Map2k1 11 0.80 2.44 8.01
166 INT171367 Phosphorylation of Map2k1 31 0.58 32.87 8
167 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99
168 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98
169 INT81345 Gene_expression of ADRBK1 21 0.70 2.89 7.9
170 INT111533 Positive_regulation of Gene_expression of Nfkb1 27 0.52 17.32 7.89
171 INT135441 Positive_regulation of Map2k1 15 0.67 6.6 7.87
172 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
173 INT22491 Binding of Atrn 23 0.30 4.51 7.79
174 INT121977 Phosphorylation of Nfkb1 15 0.51 9.83 7.77
175 INT116552 Positive_regulation of Localization of Nfkb1 16 0.61 12.7 7.74
176 INT20234 Regulation of Gene_expression of Ptgs1 11 0.44 6.55 7.72
177 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
178 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64
179 INT5409 Negative_regulation of G6pd 33 0.57 29.21 7.64
180 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52
181 INT81537 Regulation of Gene_expression of Nfkb1 10 0.57 7.09 7.48
182 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
183 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
184 INT5195 Negative_regulation of Lpo 32 0.59 14.45 7.3
185 INT98856 Negative_regulation of Gene_expression of Adrbk1 5 0.56 0.43 7.29
186 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25
187 INT49751 Negative_regulation of Positive_regulation of PTGS1 12 0.45 4.73 7.23
188 INT50779 Positive_regulation of Gene_expression of Adrbk1 9 0.56 2.79 7.23
189 INT85764 Binding of PEBP1 9 0.44 4.52 7.2
190 INT111398 Localization of Mmp2 37 0.76 23.78 7.17
191 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
192 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11
193 INT197493 Localization of Apoe 61 0.79 27.48 7.06
194 INT16722 Negative_regulation of MPO 25 0.59 18.55 6.99
195 INT88079 Gene_expression of Chrna4 20 0.76 8.52 6.98
196 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
197 INT168600 Binding of Mmp9 14 0.44 12.79 6.92
198 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
199 INT140170 Binding of Nqo1 24 0.38 36.16 6.79
200 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
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