GO:0006991

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Name response to sterol depletion
Categary Process
Go Slim No
Go Link GO:0006991
Unique Molecular Interactions 13
Total Molecular Interactions 14
Total Single Events 46
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to sterol depletion. They are ordered first by their pain relevance and then by number of times they were reported for response to sterol depletion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT115148 PPARG Negative_regulation of Gene_expression of INSIG2 1 0.01 0.34 0.21
2 INT262197 Nr1i2 Positive_regulation of Insig1 2 0.23 0 0.12
3 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
4 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
5 INT129093 Binding of Lyn and TCHP 1 0.00 0.49 0.12
6 INT129092 Binding of GRP and Lyn 1 0.00 0.48 0.12
7 INT281192 Casr Positive_regulation of Insig1 1 0.23 0 0.12
8 INT335129 PPARA Positive_regulation of Gene_expression of Insig1 1 0.20 0.15 0.07
9 INT287223 Pdx1 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
10 INT287222 Cytip Regulation of Transcription of Insig1 1 0.02 0.56 0.05
11 INT287221 Tcf3 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
12 INT262212 Positive_regulation of Nr1i2 Positive_regulation of Insig1 1 0.12 0 0
13 INT6131 INSIG1 Positive_regulation of POMC 1 0.06 0.61 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to sterol depletion. They are ordered first by their pain relevance and then by number of times they were reported in response to sterol depletion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT270631 Gene_expression of Insig1 15 0.32 5.19 1.43
2 INT117091 Positive_regulation of Lyn 1 0.49 0.41 0.56
3 INT62104 Localization of INSIG2 1 0.01 0 0.5
4 INT281177 Regulation of Insig1 2 0.25 0.93 0.33
5 INT297865 Positive_regulation of Gene_expression of Insig1 2 0.21 0.4 0.28
6 INT262077 Positive_regulation of Insig1 3 0.29 0.34 0.21
7 INT270625 Regulation of Gene_expression of Insig1 2 0.19 1.4 0.21
8 INT297868 Regulation of Regulation of Insig1 1 0.11 0.82 0.21
9 INT115158 Gene_expression of INSIG2 1 0.01 0.33 0.21
10 INT287201 Transcription of Insig1 2 0.29 2.87 0.05
11 INT262064 Negative_regulation of Positive_regulation of Insig1 1 0.09 0.05 0
12 INT297864 Positive_regulation of Transcription of Insig1 1 0.21 2.31 0
13 INT6132 Regulation of INSIG1 1 0.03 1.23 0
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