GO:0007016

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Name cytoskeletal anchoring at plasma membrane
Categary Process
Go Slim No
Go Link GO:0007016
Unique Molecular Interactions 73
Total Molecular Interactions 105
Total Single Events 605
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cytoskeletal anchoring at plasma membrane. They are ordered first by their pain relevance and then by number of times they were reported for cytoskeletal anchoring at plasma membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64
2 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82
3 INT263236 DAG1 Positive_regulation of Prkcg 2 0.01 0.31 0.7
4 INT27690 Ins1 Negative_regulation of GYPA 1 0.00 0.73 0.69
5 INT168129 Binding of Yy1 and Positive_regulation of Transcription of Tln2 1 0.02 0 0.44
6 INT168132 Binding of Yy1 and Tln2 1 0.01 0 0.43
7 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
8 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
9 INT326587 GYPA Regulation of DDC 1 0.08 0.83 0.33
10 INT46664 GYPA Positive_regulation of Gucy2f 1 0.00 0 0.32
11 INT189670 CHKB Negative_regulation of Gene_expression of DAG1 1 0.11 0 0.24
12 INT335464 Binding of DAG1 and PRKCA 1 0.03 0 0.22
13 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2
14 INT66279 Binding of FLNB and HLA-B 1 0.41 0.57 0.19
15 INT312858 Negative_regulation of Binding of GYPA and IFNG 1 0.20 0.41 0.17
16 INT312857 Binding of GYPA and IFNG 1 0.17 0.41 0.17
17 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
18 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
19 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
20 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
21 INT352763 Sms Regulation of Gene_expression of DAG1 1 0.08 0.64 0.11
22 INT243996 Binding of Dag1 and Dmd 1 0.04 0.08 0.11
23 INT303179 Binding of Dlgap1 and Shank1 1 0.22 0.31 0.1
24 INT303180 Trim3 Negative_regulation of Shank1 1 0.40 0 0.09
25 INT244027 Binding of Dag1 and Helt 1 0.00 0.05 0.08
26 INT339111 Binding of ERBB2 and JUP 1 0.38 0.62 0.07
27 INT283126 Dag1 Positive_regulation of Localization of Aqp4 1 0.47 0.2 0.07
28 INT231120 GYPA Positive_regulation of Gene_expression of GSTM1 1 0.05 0.15 0.07
29 INT352766 DAG1 Positive_regulation of Prkd1 1 0.15 0.38 0.07
30 INT339108 Binding of ESR1 and JUP 1 0.38 0.62 0.07
31 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
32 INT303176 Gene_expression of Trim3 Positive_regulation of Protein_catabolism of Shank1 1 0.44 0 0.07
33 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06
34 INT110960 Binding of CD2 and GYPA 1 0.01 0.19 0.05
35 INT352762 DAG1 Regulation of Sms 1 0.03 0.37 0.05
36 INT303170 Gene_expression of Trim3 Negative_regulation of Shank1 1 0.40 0.12 0.04
37 INT352764 DAG1 Positive_regulation of Sms 1 0.06 0.11 0.03
38 INT192044 Binding of DSP and Jup 2 0.24 2.39 0
39 INT303159 Trim3 Negative_regulation of Gene_expression of Shank1 1 0.40 0 0
40 INT234995 Binding of CDH16 and Jup 1 0.00 0.27 0
41 INT316354 Binding of CR1 and Gypa 1 0.05 0.43 0
42 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
43 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
44 INT303185 Binding of Shank1 and Trim3 1 0.35 0 0
45 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0
46 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
47 INT234969 Jup Regulation of Gene_expression of Dsp 1 0.01 0.54 0
48 INT136693 Gtf3a Positive_regulation of Ctnnb1 1 0.05 0 0
49 INT235007 Binding of DSG1 and Jup 1 0.08 0.36 0
50 INT343541 PTHLH Positive_regulation of GYPA 1 0.03 0.95 0
51 INT235005 Positive_regulation of Binding of DSG1 and Jup 1 0.08 0.36 0
52 INT234983 IgG Positive_regulation of Protein_catabolism of Jup 1 0.03 0.61 0
53 INT230762 Binding of DAG1 and Tbx15 1 0.00 0.21 0
54 INT192045 Jup Positive_regulation of RYR2 1 0.11 0.29 0
55 INT353985 Binding of GYPA and POMT1 1 0.04 0.72 0
56 INT303161 Gene_expression of Trim3 Positive_regulation of Shank1 1 0.44 0 0
57 INT234970 Binding of Jup and Lat 1 0.01 0 0
58 INT266555 Mapk8 Regulation of JUP 1 0.08 0.1 0
59 INT220821 Binding of MAX and Ctnnb1 1 0.09 0.13 0
60 INT283122 Binding of Dag1 and Sptbn1 1 0.00 0.07 0
61 INT321968 Rock1 Positive_regulation of EZR 1 0.42 1.02 0
62 INT343549 GLI2 Positive_regulation of GYPA 1 0.05 0.95 0
63 INT234987 Binding of Jup and Dsp 1 0.01 0.18 0
64 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0
65 INT303169 Trim3 Regulation of Gene_expression of Shank1 1 0.42 0 0
66 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0
67 INT304608 Binding of GYPA and Epb4.1 1 0.00 0.4 0
68 INT352765 DAG1 Regulation of Localization of Prkd1 1 0.09 0.09 0
69 INT192042 Binding of Jup and Ryr2 1 0.17 1.09 0
70 INT234982 Binding of Jup and Pkp1 1 0.00 0 0
71 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0
72 INT303163 Shank1 Positive_regulation of Trim3 1 0.47 0 0
73 INT303173 Negative_regulation of Trim3 Negative_regulation of Shank1 1 0.40 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cytoskeletal anchoring at plasma membrane. They are ordered first by their pain relevance and then by number of times they were reported in cytoskeletal anchoring at plasma membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT18391 Positive_regulation of GYPA 41 0.40 16.47 8.69
2 INT10980 Gene_expression of GYPA 40 0.78 15.32 5.51
3 INT74508 Gene_expression of Gypa 7 0.75 2.15 2.89
4 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
5 INT15745 Negative_regulation of GYPA 18 0.43 8.01 2.74
6 INT15744 Localization of GYPA 12 0.64 7.19 2.61
7 INT168115 Transcription of Tln2 1 0.02 0 2.06
8 INT110961 Binding of GYPA 14 0.36 6.66 2.03
9 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
10 INT50895 Regulation of GYPA 10 0.60 4.05 1.95
11 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
12 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
13 INT173328 Positive_regulation of DAG1 6 0.31 1.74 1.36
14 INT202817 Gene_expression of Dag1 16 0.75 7.82 1.3
15 INT58479 Positive_regulation of Gypa 3 0.40 0.76 1.24
16 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
17 INT128413 Positive_regulation of Shank1 2 0.70 0.61 1.16
18 INT189771 Gene_expression of DAG1 5 0.27 4.14 1.12
19 INT211095 Negative_regulation of Dag1 14 0.57 7.18 1.07
20 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
21 INT242171 Protein_catabolism of JUP 4 0.96 0.91 1.01
22 INT128411 Regulation of Shank1 2 0.45 0.81 0.95
23 INT170238 Negative_regulation of Gene_expression of GYPA 5 0.42 1.74 0.88
24 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
25 INT64044 Localization of DAG1 3 0.59 0.27 0.87
26 INT168118 Negative_regulation of Transcription of Tln2 1 0.02 0 0.84
27 INT50818 Positive_regulation of Positive_regulation of FLNB 1 0.49 0.97 0.7
28 INT50819 Positive_regulation of FLNB 1 0.49 0.97 0.7
29 INT283119 Regulation of Dag1 4 0.44 1.98 0.65
30 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
31 INT283110 Localization of Dag1 5 0.73 3.14 0.61
32 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
33 INT266535 Phosphorylation of JUP 3 0.79 0.63 0.49
34 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
35 INT242168 Transcription of JUP 4 0.67 1.17 0.46
36 INT168120 Regulation of Transcription of Tln2 1 0.01 0 0.45
37 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
38 INT130966 Binding of EZR 2 0.36 0.24 0.41
39 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
40 INT303211 Gene_expression of Shank1 1 0.64 0.48 0.4
41 INT18390 Positive_regulation of Positive_regulation of GYPA 2 0.40 1.42 0.39
42 INT283120 Regulation of Gene_expression of Dag1 4 0.52 1.32 0.38
43 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
44 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
45 INT284325 Positive_regulation of Gene_expression of DAG1 3 0.13 1.08 0.36
46 INT38810 Positive_regulation of Localization of GYPA 1 0.01 0.39 0.35
47 INT242169 Positive_regulation of Protein_catabolism of JUP 1 0.49 0.23 0.34
48 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32
49 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
50 INT170241 Positive_regulation of Gene_expression of GYPA 3 0.28 1.68 0.27
51 INT221860 Negative_regulation of Jup 9 0.15 6.82 0.26
52 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
53 INT311755 Positive_regulation of Negative_regulation of GYPA 1 0.21 1.78 0.23
54 INT286203 Protein_catabolism of Dag1 2 0.26 1.56 0.22
55 INT316917 Negative_regulation of Protein_catabolism of Dag1 1 0.12 0.44 0.21
56 INT283102 Positive_regulation of Dag1 1 0.49 1.31 0.21
57 INT234903 Gene_expression of Jup 1 0.23 7.1 0.2
58 INT243937 Binding of Dag1 1 0.05 0.13 0.19
59 INT157568 Binding of FLNB 1 0.47 0.19 0.18
60 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
61 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
62 INT283105 Positive_regulation of Gene_expression of Dag1 1 0.67 1.19 0.17
63 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
64 INT303216 Protein_catabolism of Shank1 1 0.83 0 0.15
65 INT205083 Positive_regulation of JUP 6 0.49 5.51 0.13
66 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
67 INT287283 Gene_expression of EZR 1 0.01 0.14 0.12
68 INT303217 Binding of Shank1 1 0.36 0 0.11
69 INT303233 Negative_regulation of Gene_expression of Shank1 1 0.49 0.07 0.1
70 INT156483 Regulation of Gene_expression of GYPA 1 0.00 0.09 0.1
71 INT326597 Negative_regulation of Localization of GYPA 1 0.16 1.51 0.1
72 INT242173 Positive_regulation of Gene_expression of JUP 2 0.49 2.37 0.09
73 INT283103 Regulation of Localization of Dag1 1 0.44 0.32 0.09
74 INT309877 Localization of JUP 2 0.73 1.38 0.08
75 INT339206 Negative_regulation of Localization of JUP 1 0.41 1.1 0.08
76 INT234894 Negative_regulation of Protein_catabolism of Jup 1 0.17 2.87 0.08
77 INT303212 Positive_regulation of Protein_catabolism of Shank1 1 0.42 0 0.08
78 INT234866 Regulation of Jup 2 0.08 0.58 0.06
79 INT303195 Positive_regulation of Gene_expression of Shank1 1 0.42 0.08 0.06
80 INT234899 Positive_regulation of Protein_catabolism of Jup 1 0.21 0.88 0.06
81 INT329585 Regulation of Negative_regulation of Jup 1 0.01 0.23 0.06
82 INT234931 Protein_catabolism of Jup 1 0.29 2.23 0.06
83 INT234915 Positive_regulation of Gene_expression of Jup 1 0.15 2.7 0.06
84 INT341884 Positive_regulation of Localization of DAG1 1 0.03 0.21 0.06
85 INT352747 Regulation of DAG1 1 0.16 0.99 0.05
86 INT303204 Negative_regulation of Shank1 1 0.42 0.11 0.04
87 INT234890 Phosphorylation of Jup 1 0.24 1.56 0.03
88 INT326599 Positive_regulation of Binding of GYPA 1 0.14 0.88 0.03
89 INT234867 Localization of Jup 1 0.24 2.84 0.03
90 INT266537 Positive_regulation of Phosphorylation of JUP 2 0.49 0.29 0
91 INT76959 Binding of Ctnnb1 2 0.34 0.69 0
92 INT266534 Negative_regulation of Phosphorylation of JUP 2 0.41 0.15 0
93 INT242174 Negative_regulation of Gene_expression of JUP 2 0.41 2.58 0
94 INT221864 Binding of JUP 2 0.36 1.05 0
95 INT289267 Binding of Gypa 2 0.05 1.7 0
96 INT221859 Binding of Jup 2 0.14 2.21 0
97 INT154343 Localization of Gypa 2 0.14 0.15 0
98 INT303227 Regulation of Negative_regulation of Shank1 1 0.26 0 0
99 INT316324 Negative_regulation of Binding of Gypa 1 0.04 0.52 0
100 INT309874 Positive_regulation of Binding of JUP 1 0.49 0.32 0
101 INT230651 Phosphorylation of Ctnnb1 1 0.10 0 0
102 INT230674 Positive_regulation of Phosphorylation of Ctnnb1 1 0.06 0 0
103 INT352742 Regulation of Gene_expression of DAG1 1 0.12 0.14 0
104 INT326137 Protein_catabolism of Ctnnb1 1 0.02 1.08 0
105 INT355576 Negative_regulation of Negative_regulation of Ctnnb1 1 0.02 1.14 0
106 INT234877 Positive_regulation of Binding of Jup 1 0.21 0.24 0
107 INT242170 Negative_regulation of JUP 1 0.42 0.85 0
108 INT230759 Binding of DAG1 1 0.03 0.21 0
109 INT220769 Positive_regulation of Positive_regulation of Ctnnb1 1 0.10 0 0
110 INT321543 Negative_regulation of Tln2 1 0.07 0.89 0
111 INT303202 Negative_regulation of Protein_catabolism of Shank1 1 0.49 0 0
112 INT303209 Positive_regulation of Positive_regulation of Shank1 1 0.34 0 0
113 INT316325 Positive_regulation of Binding of Gypa 1 0.06 0.43 0
114 INT283107 Transcription of Dag1 1 0.61 0.44 0
115 INT311756 Negative_regulation of Negative_regulation of GYPA 1 0.16 0.24 0
116 INT283101 Negative_regulation of Gene_expression of Dag1 1 0.57 0.96 0
117 INT303193 Localization of Shank1 1 0.62 0.19 0
118 INT303199 Regulation of Gene_expression of Shank1 1 0.23 0 0
119 INT321549 Regulation of Tln2 1 0.03 0.52 0
120 INT309876 Regulation of JUP 1 0.60 0.67 0
121 INT234918 Positive_regulation of Jup 1 0.15 1.08 0
122 INT283113 Regulation of Transcription of Dag1 1 0.52 0.44 0
123 INT309875 Regulation of Gene_expression of JUP 1 0.44 0.39 0
124 INT321563 Gene_expression of Tln2 1 0.03 0.43 0
125 INT303232 Regulation of Protein_catabolism of Shank1 1 0.38 0 0
126 INT321966 Positive_regulation of EZR 1 0.45 1 0
127 INT234896 Negative_regulation of Gene_expression of Jup 1 0.13 0.54 0
128 INT352733 Negative_regulation of Localization of DAG1 1 0.11 0.06 0
129 INT355092 Positive_regulation of Transcription of JUP 1 0.49 0.05 0
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