GO:0007029

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Name endoplasmic reticulum organization
Categary Process
Go Slim No
Go Link GO:0007029
Unique Molecular Interactions 66
Total Molecular Interactions 97
Total Single Events 803
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for endoplasmic reticulum organization. They are ordered first by their pain relevance and then by number of times they were reported for endoplasmic reticulum organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 0.37 0.17 1.44
2 INT150680 Pomc Negative_regulation of Gene_expression of Eif2ak3 1 0.35 0.07 0.8
3 INT96282 Cav2 Regulation of Positive_regulation of Gabrg1 1 0.25 0 0.48
4 INT241679 EIF2AK3 Positive_regulation of Atf4 1 0.06 0.46 0.4
5 INT77753 Abnormal Regulation of CACNA1S 1 0.00 0.78 0.28
6 INT214412 CASQ1 Regulation of JUND 1 0.02 0.46 0.24
7 INT130691 CA2 Positive_regulation of EIF2AK3 1 0.16 0.59 0.24
8 INT260835 NRP2 Positive_regulation of Eif2ak3 1 0.00 0.73 0.23
9 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
10 INT131963 Binding of CAV2 and ATXN2 1 0.04 1.39 0.21
11 INT121807 CACNA1A Regulation of CAV2 1 0.01 0.25 0.2
12 INT121806 PHF21A Regulation of CAV2 1 0.00 0.24 0.2
13 INT343644 Grm5 Positive_regulation of Cav2 1 0.05 0 0.19
14 INT355305 Use1 Positive_regulation of Gene_expression of Clec2i 1 0.01 3 0.18
15 INT355304 Use1 Positive_regulation of Clec2i 1 0.01 3 0.18
16 INT355307 Use1 Positive_regulation of Gene_expression of Clec5a 1 0.02 2.97 0.17
17 INT355303 Use1 Positive_regulation of Clec5a 1 0.02 2.97 0.17
18 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16
19 INT293712 Binding of Adra2a and Atl1 1 0.06 0.83 0.15
20 INT250778 Binding of Socs3 and Atl1 1 0.01 0.6 0.14
21 INT317162 Binding of Bdnf and Htt 1 0.51 0.2 0.12
22 INT319315 Binding of Ap2a2 and Htt 1 0.28 0.64 0.11
23 INT215884 Eif2ak3 Positive_regulation of Gene_expression of Musd1 1 0.01 0.96 0.09
24 INT215874 Positive_regulation of Eif2ak3 Positive_regulation of Positive_regulation of Ddit3 1 0.47 0.31 0.07
25 INT215883 Eif2ak3 Regulation of Musd1 1 0.00 0.8 0.06
26 INT215878 Eif2ak3 Positive_regulation of Localization of Ins1 1 0.04 0.96 0.06
27 INT215877 Atf4 Regulation of Eif2ak3 1 0.44 0.21 0.06
28 INT287695 Binding of Cd53 and Use1 1 0.00 0.12 0.06
29 INT215873 Ddit3 Regulation of Eif2ak3 1 0.39 0.2 0.06
30 INT355439 Pdia3 Regulation of Gene_expression of Eif2ak3 1 0.01 0.83 0.05
31 INT317181 Binding of Htt and Uts2r 1 0.04 0 0.05
32 INT5608 Gnl3 Regulation of Eif2ak3 1 0.05 0 0.04
33 INT244464 EIF2AK3 Positive_regulation of Positive_regulation of EIF2S2 1 0.17 0.37 0.04
34 INT244463 EIF2AK3 Regulation of Phosphorylation of EIF2S2 1 0.09 0.37 0.04
35 INT306527 Binding of Htt and Aifm1 1 0.20 0.82 0.04
36 INT271025 Binding of Car2 and Casq1 1 0.03 0.7 0.03
37 INT317161 Htt Regulation of Transcription of Bdnf 1 0.48 0.41 0.03
38 INT256707 Eif2ak3 Regulation of Gene_expression of Wfs1 1 0.10 0.78 0.03
39 INT200311 Htt Positive_regulation of Rest 1 0.05 0.75 0.03
40 INT244454 Binding of EIF2AK3 and SIL1 1 0.05 0.41 0
41 INT121179 Binding of Htt and Rest 1 0.07 0.45 0
42 INT309515 Xrcc6 Regulation of Gene_expression of Htt 1 0.32 0.08 0
43 INT121177 Binding of Bdnf and Htt 1 0.23 0.44 0
44 INT203853 Eif2ak3 Positive_regulation of Eif2ak1 1 0.05 0.63 0
45 INT309521 PRKDC Regulation of Gene_expression of Htt 1 0.41 0.08 0
46 INT121180 Htt Negative_regulation of Bdnf 1 0.43 0.47 0
47 INT314986 Ins1 Negative_regulation of CACNA1S 1 0.00 0.08 0
48 INT309519 Xrcc5 Regulation of Gene_expression of Htt 1 0.18 0.08 0
49 INT261893 Binding of Htt and Hap1 1 0.13 0.49 0
50 INT214980 Binding of Cav2 and Sigmar1 1 0.02 0.07 0
51 INT317163 Htt Regulation of Bdnf 1 0.29 0.19 0
52 INT244466 EIF2AK3 Positive_regulation of Localization of SIL1 1 0.06 0.47 0
53 INT292504 Mlph Regulation of EIF2AK3 1 0.00 0.21 0
54 INT309516 Htt Positive_regulation of Gene_expression of Xrcc6 1 0.49 0.06 0
55 INT121176 Htt Regulation of Bdnf 1 0.17 0.77 0
56 INT309509 Negative_regulation of Binding of Xrcc6 and Htt 1 0.31 0.41 0
57 INT309510 Htt Regulation of Gene_expression of Xrcc6 1 0.19 0.15 0
58 INT309508 Htt Negative_regulation of Binding of Xrcc6 1 0.31 0.48 0
59 INT296929 Gene_expression of Casq1 Positive_regulation of Tmie 1 0.00 0.43 0
60 INT309514 Positive_regulation of Binding of Xrcc6 and Htt 1 0.33 0 0
61 INT296930 Casq1 Negative_regulation of RYR1 1 0.00 0.38 0
62 INT244465 Binding of EIF2AK3 and ATF6 1 0.14 0.69 0
63 INT215341 Binding of Htt and Sp1 1 0.03 0.25 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for endoplasmic reticulum organization. They are ordered first by their pain relevance and then by number of times they were reported in endoplasmic reticulum organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT109031 Positive_regulation of Eif2ak3 44 0.69 21.11 14.72
2 INT109034 Gene_expression of Eif2ak3 37 0.77 17.11 14.19
3 INT150678 Positive_regulation of Gene_expression of Eif2ak3 17 0.69 6.64 8.99
4 INT36757 Gene_expression of Eif2ak3 4 0.74 0.15 6.06
5 INT137336 Phosphorylation of Eif2ak3 14 0.79 4.72 4.78
6 INT5602 Positive_regulation of Eif2ak3 9 0.66 0 4.04
7 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
8 INT292058 Positive_regulation of Cav2 7 0.67 3.43 2.89
9 INT149314 Negative_regulation of CAV2 5 0.42 1.21 2.76
10 INT282270 Gene_expression of Cav2 11 0.57 3.53 2.72
11 INT203819 Binding of Eif2ak3 9 0.37 5.94 2.57
12 INT15695 Positive_regulation of EIF2AK3 12 0.67 7.01 2.56
13 INT36758 Positive_regulation of Gene_expression of Eif2ak3 1 0.48 0 2.21
14 INT151878 Gene_expression of CAV2 18 0.66 9.26 2.17
15 INT105824 Regulation of Casq1 4 0.07 2.66 2.1
16 INT287525 Localization of CAV2 5 0.47 5.32 2
17 INT36755 Positive_regulation of Localization of Eif2ak3 1 0.48 0 1.97
18 INT36756 Localization of Eif2ak3 1 0.71 0 1.96
19 INT150675 Regulation of Gene_expression of Eif2ak3 3 0.40 1.11 1.93
20 INT292051 Negative_regulation of Cav2 6 0.41 2.52 1.9
21 INT36759 Regulation of Gene_expression of Eif2ak3 1 0.59 0 1.74
22 INT109033 Positive_regulation of Positive_regulation of Eif2ak3 2 0.45 2.36 1.59
23 INT150677 Negative_regulation of Eif2ak3 9 0.58 6.24 1.46
24 INT195822 Gene_expression of Use1 6 0.09 1.53 1.42
25 INT215864 Localization of Eif2ak3 5 0.75 3.26 1.36
26 INT18337 Transcription of Eif2ak3 3 0.68 0 1.36
27 INT127900 Phosphorylation of EIF2AK3 14 0.80 7.99 1.22
28 INT163159 Gene_expression of Casq1 2 0.58 1.21 1.09
29 INT108997 Localization of Htt 28 0.77 3.76 1.07
30 INT137338 Regulation of Eif2ak3 8 0.45 5.5 1.07
31 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96
32 INT292059 Positive_regulation of Gene_expression of Cav2 3 0.42 0.88 0.92
33 INT240368 Positive_regulation of Localization of Eif2ak3 1 0.34 0.66 0.87
34 INT109032 Negative_regulation of Positive_regulation of Eif2ak3 1 0.38 0.94 0.85
35 INT154886 Gene_expression of Htt 18 0.76 15.51 0.82
36 INT208511 Positive_regulation of Use1 24 0.13 11.51 0.8
37 INT127899 Gene_expression of EIF2AK3 8 0.75 2.89 0.8
38 INT154053 Negative_regulation of Gene_expression of Eif2ak3 2 0.43 1.28 0.79
39 INT127901 Positive_regulation of Gene_expression of EIF2AK3 3 0.49 1.8 0.77
40 INT250771 Gene_expression of Atl1 3 0.43 2.45 0.75
41 INT152326 Regulation of Gene_expression of CAV2 2 0.36 0.44 0.74
42 INT151877 Positive_regulation of Gene_expression of CAV2 2 0.40 0.39 0.72
43 INT70104 Positive_regulation of CACNA1S 6 0.47 5.92 0.68
44 INT127898 Positive_regulation of Phosphorylation of EIF2AK3 3 0.49 2.03 0.67
45 INT98239 Negative_regulation of Htt 13 0.43 7.84 0.6
46 INT287206 Regulation of Gene_expression of Htt 6 0.50 3.27 0.57
47 INT121810 Positive_regulation of CAV2 2 0.28 0.55 0.57
48 INT215340 Localization of Htt 10 0.61 5.12 0.55
49 INT315028 Regulation of Cav2 2 0.43 0.86 0.54
50 INT287204 Protein_catabolism of Htt 6 0.99 2.8 0.53
51 INT5601 Regulation of Eif2ak3 1 0.43 0 0.53
52 INT119230 Negative_regulation of Htt 5 0.42 2.99 0.5
53 INT18336 Positive_regulation of Positive_regulation of Eif2ak3 1 0.33 0 0.49
54 INT298539 Binding of CAV2 2 0.39 0.95 0.48
55 INT243418 Binding of Htt 14 0.30 5.94 0.44
56 INT165597 Positive_regulation of Htt 8 0.60 4.27 0.44
57 INT343628 Regulation of Positive_regulation of Cav2 1 0.19 0 0.4
58 INT15696 Regulation of EIF2AK3 2 0.26 1.1 0.39
59 INT132864 Binding of Htt 15 0.46 2.34 0.38
60 INT287207 Regulation of Protein_catabolism of Htt 3 0.45 1.73 0.35
61 INT15697 Negative_regulation of EIF2AK3 1 0.41 0 0.33
62 INT15698 Transcription of EIF2AK3 1 0.52 0 0.32
63 INT127902 Negative_regulation of Gene_expression of EIF2AK3 1 0.42 0.47 0.3
64 INT254877 Positive_regulation of Gene_expression of Htt 15 0.64 6.29 0.28
65 INT292064 Positive_regulation of Positive_regulation of Cav2 1 0.49 0.5 0.28
66 INT313362 Negative_regulation of Gene_expression of Use1 1 0.05 0 0.23
67 INT313360 Positive_regulation of Gene_expression of Use1 1 0.06 0 0.23
68 INT287205 Regulation of Htt 5 0.45 3.56 0.22
69 INT208509 Negative_regulation of Use1 3 0.02 0.73 0.22
70 INT121809 Regulation of Positive_regulation of CAV2 1 0.25 0.26 0.2
71 INT313361 Localization of Use1 1 0.09 0.06 0.16
72 INT329386 Positive_regulation of Localization of CAV2 1 0.17 0.19 0.16
73 INT349644 Negative_regulation of Atl1 1 0.02 0.69 0.14
74 INT311452 Gene_expression of CASQ1 1 0.74 7.58 0.14
75 INT215861 Positive_regulation of Negative_regulation of Eif2ak3 1 0.50 1.04 0.13
76 INT166811 Regulation of Casq1 3 0.04 1.18 0.1
77 INT250770 Positive_regulation of Localization of Atl1 1 0.28 0.49 0.1
78 INT250766 Localization of Atl1 1 0.41 0.49 0.09
79 INT214973 Binding of Cav2 2 0.03 0.57 0.08
80 INT166810 Gene_expression of Casq1 2 0.10 2.16 0.08
81 INT166809 Binding of Casq1 1 0.05 0.34 0.08
82 INT287203 Negative_regulation of Gene_expression of Htt 7 0.37 5.08 0.07
83 INT327713 Negative_regulation of Casq1 1 0.02 0.11 0.06
84 INT261890 Positive_regulation of Gene_expression of Htt 1 0.43 0.85 0.06
85 INT355277 Positive_regulation of Positive_regulation of Use1 1 0.08 0.85 0.06
86 INT108117 Regulation of CACNA1S 1 0.39 0.25 0.05
87 INT214968 Localization of Cav2 1 0.05 0.08 0.05
88 INT317175 Positive_regulation of Localization of Htt 1 0.48 0 0.05
89 INT306521 Transcription of Htt 1 0.69 4.13 0.05
90 INT331204 Negative_regulation of Binding of Htt 1 0.04 0.64 0.04
91 INT261891 Negative_regulation of Gene_expression of Htt 1 0.37 1.12 0.04
92 INT207781 Gene_expression of CACNA1S 3 0.63 0.9 0.03
93 INT311456 Positive_regulation of Gene_expression of CASQ1 1 0.66 0.79 0.03
94 INT271021 Binding of Casq1 1 0.03 0.64 0.03
95 INT207782 Binding of CACNA1S 1 0.30 0.53 0.03
96 INT204938 Positive_regulation of Casq1 1 0.08 0.17 0.03
97 INT154887 Transcription of Htt 3 0.66 0 0
98 INT261886 Regulation of Htt 2 0.43 2.06 0
99 INT281600 Positive_regulation of Casq1 2 0.05 0.66 0
100 INT313014 Positive_regulation of Binding of Htt 2 0.13 0.91 0
101 INT341938 Positive_regulation of Negative_regulation of Htt 1 0.07 0.65 0
102 INT254883 Negative_regulation of Positive_regulation of Htt 1 0.05 1.14 0
103 INT311453 Binding of CASQ1 1 0.31 0.44 0
104 INT208510 Regulation of Use1 1 0.01 0 0
105 INT296911 Positive_regulation of Gene_expression of Casq1 1 0.09 1.49 0
106 INT244533 Negative_regulation of Phosphorylation of EIF2AK3 1 0.20 0.39 0
107 INT311445 Positive_regulation of CASQ1 1 0.39 0.7 0
108 INT282279 Regulation of Gene_expression of Cav2 1 0.05 0.39 0
109 INT296922 Negative_regulation of Casq1 1 0.06 0.38 0
110 INT296909 Regulation of Transcription of Casq1 1 0.08 1.15 0
111 INT355275 Transcription of Use1 1 0.11 0.93 0
112 INT317177 Negative_regulation of Transcription of Htt 1 0.41 0 0
113 INT296927 Localization of Casq1 1 0.10 0.32 0
114 INT332316 Negative_regulation of Positive_regulation of Cav2 1 0.22 0 0
115 INT332317 Negative_regulation of Gene_expression of Cav2 1 0.25 0 0
116 INT296916 Negative_regulation of Gene_expression of Casq1 1 0.06 0.44 0
117 INT332315 Positive_regulation of Negative_regulation of Cav2 1 0.26 0 0
118 INT311454 Regulation of CASQ1 1 0.43 0.07 0
119 INT309469 Negative_regulation of Localization of Htt 1 0.34 0.13 0
120 INT296926 Transcription of Casq1 1 0.10 1.85 0
121 INT271085 Positive_regulation of Regulation of Eif2ak3 1 0.03 0.66 0
122 INT317170 Regulation of Binding of Htt 1 0.43 0 0
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