GO:0007043

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Name cell-cell junction assembly
Categary Process
Go Slim No
Go Link GO:0007043
Unique Molecular Interactions 96
Total Molecular Interactions 156
Total Single Events 1171
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell-cell junction assembly. They are ordered first by their pain relevance and then by number of times they were reported for cell-cell junction assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT181493 TRPV4 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07
2 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02
3 INT263227 Positive_regulation of Prkcg Regulation of Trpv4 1 0.07 0.95 1
4 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
5 INT159688 Trpv4 Negative_regulation of Trpv3 1 0.31 0.41 0.76
6 INT159689 Trpv4 Negative_regulation of Trpv1 1 0.36 0.41 0.76
7 INT159687 Trpv4 Negative_regulation of Trpv2 1 0.32 0.41 0.76
8 INT309735 Binding of CALM3 and TRPV4 1 0.14 0 0.75
9 INT322128 Binding of Ca2 and Trpv4 1 0.03 1.1 0.75
10 INT120819 Binding of ASIC3 and Lin7b 1 0.01 0 0.73
11 INT120818 Lin7b Positive_regulation of ASIC3 1 0.01 0 0.71
12 INT241247 Binding of Pkd2 and Trpv4 1 0.54 1.22 0.52
13 INT263228 Prkcg Regulation of Trpv4 1 0.07 0.36 0.5
14 INT263235 Trpv4 Regulation of Trpv1 1 0.17 0.7 0.5
15 INT322131 Binding of Prkcg and Trpv4 1 0.04 0.75 0.46
16 INT120817 Binding of Dlg4 and Lin7b 1 0.00 0 0.34
17 INT279705 CALM3 Regulation of TRPV4 2 0.08 0 0.33
18 INT322133 Trpv4 Regulation of Ca2 1 0.04 0.16 0.33
19 INT259130 KLK7 Positive_regulation of Binding of DSG1 1 0.51 0.91 0.31
20 INT259131 KLK7 Positive_regulation of DSG1 1 0.51 0.91 0.31
21 INT221918 TRPV4 Positive_regulation of TRPM8 1 0.05 0 0.28
22 INT322132 Binding of Mbp and Trpv4 1 0.11 0.39 0.27
23 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26
24 INT309751 Binding of CA2 and TRPV4 1 0.08 0 0.23
25 INT118435 HGF Positive_regulation of TRPV4 1 0.54 0.13 0.2
26 INT142227 Urb1 Regulation of Trpv4 1 0.02 0.1 0.17
27 INT142229 Trpa1 Regulation of Trpv4 1 0.15 0.1 0.17
28 INT137672 Baa1 Positive_regulation of Trpv4 1 0.17 0 0.11
29 INT28816 Binding of TRPV4 and MND1 1 0.27 0.52 0.1
30 INT165324 Binding of TRPV4 and Trpv4 1 0.11 0.66 0.1
31 INT309724 Regulation of Binding of TYRP1 and TRPV4 1 0.01 0 0.09
32 INT309754 Binding of TYRP1 and TRPV4 1 0.02 0 0.09
33 INT309722 TRPV4 Positive_regulation of CA2 1 0.11 0 0.08
34 INT241246 Pkd2 Negative_regulation of Gene_expression of Trpv4 1 0.48 0.47 0.07
35 INT196124 Trpm5 Negative_regulation of Trpv4 1 0.13 0.08 0.06
36 INT196134 Gopc Negative_regulation of Trpv4 1 0.07 0.08 0.06
37 INT196126 Gopc Negative_regulation of Gene_expression of Trpv4 1 0.15 0.08 0.06
38 INT309732 CALM3 Positive_regulation of Gene_expression of TRPV4 1 0.14 0 0.06
39 INT196131 Trpm7 Negative_regulation of Trpv4 1 0.14 0.08 0.06
40 INT196130 Trpm5 Negative_regulation of Gene_expression of Trpv4 1 0.30 0.08 0.06
41 INT196129 Trpm7 Negative_regulation of Gene_expression of Trpv4 1 0.32 0.08 0.06
42 INT322130 Trpv1 Positive_regulation of Positive_regulation of Trpv4 1 0.15 0.1 0.05
43 INT333034 Trpv4 Positive_regulation of Localization of Car2 1 0.06 0 0.05
44 INT169403 Binding of TRPV1 and Trpv4 1 0.23 0.94 0.05
45 INT333032 Binding of Trpv4 and Gopc 1 0.05 0 0.04
46 INT266617 Binding of GJC1 and Tjp1 1 0.41 0.28 0.03
47 INT241253 Gene_expression of Trpv4 Positive_regulation of Gene_expression of Pkd2 1 0.52 0.29 0.03
48 INT333037 Binding of Agt and Trpv4 1 0.09 0 0.03
49 INT309744 Binding of GOPC and TRPV4 1 0.09 0 0
50 INT235002 Negative_regulation of Binding of DSG1 and Dsg3 1 0.13 1.08 0
51 INT322126 Binding of Trpv4 and Fig4 1 0.02 0 0
52 INT333035 Positive_regulation of Binding of Agt and Trpv4 1 0.11 0 0
53 INT309745 Negative_regulation of Binding of CALM3 and TRPV4 1 0.12 0 0
54 INT355587 Binding of occludin and TJP1 1 0.01 1.12 0
55 INT235007 Binding of DSG1 and Jup 1 0.08 0.36 0
56 INT333030 Binding of Itch and Trpv4 1 0.14 0 0
57 INT235005 Positive_regulation of Binding of DSG1 and Jup 1 0.08 0.36 0
58 INT333046 Binding of Trpv4 and ITCH 1 0.39 0 0
59 INT333036 Trpv4 Positive_regulation of Gene_expression of Agt 1 0.12 0 0
60 INT339977 Positive_regulation of Binding of HDAC3 and HDAC7 1 0.23 0.52 0
61 INT261833 Binding of Add3 and Trpv4 1 0.00 0.12 0
62 INT261838 Lyn Regulation of Trpv4 1 0.03 0.19 0
63 INT169448 Binding of Prkce and Trpv4 1 0.04 0.08 0
64 INT162407 TNF Positive_regulation of Gene_expression of TRPV4 1 0.47 0.22 0
65 INT261840 Binding of Mtap7 and Trpv4 1 0.05 0.12 0
66 INT234997 Binding of DSG1 and Car2 1 0.03 0.1 0
67 INT261843 Lyn Regulation of Regulation of Trpv4 1 0.03 0.19 0
68 INT235000 IgG Negative_regulation of DSG1 1 0.04 0.86 0
69 INT255384 Binding of AKR1C2 and DSG1 1 0.01 1.54 0
70 INT339978 Binding of HDAC3 and HDAC7 1 0.17 1.04 0
71 INT309736 PACSIN3 Regulation of TRPV4 1 0.55 0 0
72 INT333044 Positive_regulation of Binding of AGTR1 and Trpv4 1 0.48 0 0
73 INT234999 IgG Positive_regulation of Gene_expression of DSG1 1 0.05 0.8 0
74 INT309728 TRPV4 Positive_regulation of CFP 1 0.10 0 0
75 INT164929 Binding of Calca and Trpv4 1 0.32 0 0
76 INT235008 Binding of DSG1 and Dsg3 1 0.11 4.82 0
77 INT339980 Binding of MEF2D and HDAC7 1 0.19 0.78 0
78 INT333038 Agt Positive_regulation of Positive_regulation of Trpv4 1 0.12 0 0
79 INT235016 IgG Negative_regulation of Binding of DSG1 1 0.04 2.89 0
80 INT333043 Binding of AGTR1 and Trpv4 1 0.50 0 0
81 INT235009 Binding of DSG1 and Cdh1 1 0.02 0.87 0
82 INT125019 Binding of S100A8 and TJP1 1 0.15 0.18 0
83 INT261837 Binding of Aqp5 and Trpv4 1 0.05 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell-cell junction assembly. They are ordered first by their pain relevance and then by number of times they were reported in cell-cell junction assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT109820 Gene_expression of Trpv4 121 0.78 39.69 33.11
2 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09
3 INT119233 Positive_regulation of Trpv4 65 0.70 20.21 17.3
4 INT124702 Positive_regulation of Trpv4 21 0.69 7.14 8.2
5 INT124881 Binding of Trpv4 35 0.47 7.71 6.24
6 INT149385 Positive_regulation of TRPV4 11 0.69 7.22 6.02
7 INT118440 Gene_expression of TRPV4 20 0.71 7.33 6.01
8 INT156296 Regulation of Trpv4 20 0.45 7.84 4.86
9 INT109821 Negative_regulation of Trpv4 19 0.55 6.86 3.98
10 INT181496 Regulation of TRPV4 3 0.23 3.32 3.23
11 INT112175 Negative_regulation of Gene_expression of Trpv4 8 0.59 3.7 3.12
12 INT168744 Negative_regulation of Regulation of Trpv4 1 0.42 3.26 2.87
13 INT169402 Binding of Trpv4 8 0.47 5.13 2.78
14 INT115852 Transcription of Trpv4 9 0.71 2.23 2.65
15 INT28817 Binding of TRPV4 6 0.39 3.92 2.59
16 INT109822 Negative_regulation of Gene_expression of Trpv4 8 0.55 1.98 2.53
17 INT115199 Localization of Trpv4 12 0.79 3.65 2.5
18 INT159809 Localization of Trpv4 6 0.78 3.67 2.46
19 INT156301 Regulation of Trpv4 11 0.60 2.81 2.35
20 INT156299 Phosphorylation of Trpv4 8 0.80 2.46 2.31
21 INT152771 Gene_expression of TJP1 19 0.75 14.95 1.98
22 INT137670 Positive_regulation of Gene_expression of Trpv4 12 0.68 3.42 1.77
23 INT149153 Positive_regulation of Gene_expression of Trpv4 12 0.70 3.37 1.72
24 INT149152 Negative_regulation of Trpv4 5 0.58 1.8 1.52
25 INT140647 Gene_expression of DSG1 45 0.75 27.95 1.33
26 INT149384 Negative_regulation of TRPV4 4 0.43 2.41 1.23
27 INT181497 Regulation of Regulation of TRPV4 1 0.23 0.69 1.08
28 INT261816 Positive_regulation of Localization of Trpv4 2 0.47 1.16 1.07
29 INT238495 Negative_regulation of Gene_expression of TJP1 5 0.18 9.51 1.05
30 INT234952 Protein_catabolism of DSG1 3 0.96 5.86 0.98
31 INT156175 Positive_regulation of Positive_regulation of Trpv4 5 0.50 0.86 0.8
32 INT158547 Negative_regulation of Positive_regulation of Trpv4 2 0.57 0.47 0.77
33 INT120815 Gene_expression of Lin7b 1 0.01 0 0.71
34 INT263225 Positive_regulation of Positive_regulation of Trpv4 3 0.46 0.75 0.7
35 INT234950 Binding of DSG1 29 0.36 23.67 0.69
36 INT87445 Localization of TJP1 2 0.45 0.55 0.68
37 INT156302 Positive_regulation of Phosphorylation of Trpv4 2 0.46 0.92 0.68
38 INT120816 Binding of Lin7b 1 0.01 0 0.68
39 INT152775 Regulation of Gene_expression of TJP1 1 0.44 2.05 0.67
40 INT156303 Regulation of Regulation of Trpv4 2 0.27 0.26 0.63
41 INT234954 Negative_regulation of DSG1 22 0.42 19.5 0.62
42 INT158548 Regulation of Gene_expression of Trpv4 3 0.61 1.03 0.57
43 INT125188 Negative_regulation of Transcription of Trpv4 3 0.42 0.44 0.56
44 INT263224 Phosphorylation of Trpv4 2 0.76 0.73 0.49
45 INT137671 Negative_regulation of Positive_regulation of Trpv4 3 0.58 0.25 0.48
46 INT259152 Positive_regulation of Protein_catabolism of DSG1 1 0.48 1.6 0.44
47 INT212307 Regulation of Gene_expression of Trpv4 8 0.44 2.85 0.39
48 INT234962 Positive_regulation of Gene_expression of DSG1 5 0.48 5.41 0.37
49 INT259154 Transcription of DSG1 1 0.67 1.53 0.3
50 INT339992 Positive_regulation of Transcription of HDAC7 1 0.45 1.56 0.28
51 INT340001 Transcription of HDAC7 1 0.61 1.5 0.27
52 INT118446 Positive_regulation of Transcription of TRPV4 1 0.49 0.26 0.21
53 INT118447 Transcription of TRPV4 1 0.67 0.26 0.21
54 INT156172 Transcription of Trpv4 3 0.72 1.19 0.19
55 INT209259 Regulation of Gene_expression of TRPV4 1 0.22 0.93 0.19
56 INT277393 Gene_expression of HDAC7 2 0.65 4.71 0.18
57 INT322153 Positive_regulation of Binding of Trpv4 1 0.49 0 0.18
58 INT308526 Protein_catabolism of TJP1 1 0.07 1.18 0.17
59 INT318208 Transcription of TJP1 1 0.02 0.38 0.17
60 INT162409 Positive_regulation of Gene_expression of TRPV4 2 0.45 0 0.16
61 INT339984 Positive_regulation of HDAC7 1 0.45 1.07 0.16
62 INT333015 Regulation of Binding of Trpv4 1 0.42 0.43 0.13
63 INT189876 Binding of TJP1 3 0.14 0.29 0.1
64 INT259140 Negative_regulation of Gene_expression of DSG1 1 0.42 0.68 0.1
65 INT156173 Positive_regulation of Transcription of Trpv4 1 0.61 0.43 0.1
66 INT309764 Regulation of Binding of TRPV4 1 0.36 0 0.08
67 INT178721 Positive_regulation of DSG1 2 0.34 0.1 0.06
68 INT154990 Negative_regulation of TJP1 2 0.20 1.74 0.03
69 INT234951 Negative_regulation of Binding of DSG1 1 0.29 11.2 0.03
70 INT238493 Positive_regulation of Gene_expression of TJP1 1 0.16 2.08 0.03
71 INT234937 Localization of DSG1 5 0.66 4.14 0
72 INT277405 Negative_regulation of Gene_expression of HDAC7 2 0.41 1.52 0
73 INT234940 Regulation of DSG1 2 0.21 2.29 0
74 INT234943 Phosphorylation of DSG1 2 0.48 1.81 0
75 INT234944 Positive_regulation of Binding of DSG1 1 0.23 0.84 0
76 INT333013 Positive_regulation of Protein_catabolism of Trpv4 1 0.43 0 0
77 INT333010 Positive_regulation of Binding of Trpv4 1 0.47 0 0
78 INT158549 Negative_regulation of Transcription of Trpv4 1 0.42 0 0
79 INT156298 Negative_regulation of Phosphorylation of Trpv4 1 0.43 0.14 0
80 INT322151 Positive_regulation of Localization of Trpv4 1 0.49 0.31 0
81 INT333022 Positive_regulation of Phosphorylation of Trpv4 1 0.47 0 0
82 INT333018 Positive_regulation of Negative_regulation of Trpv4 1 0.43 0 0
83 INT154991 Positive_regulation of Negative_regulation of TJP1 1 0.17 0.06 0
84 INT339999 Positive_regulation of Gene_expression of HDAC7 1 0.45 1.97 0
85 INT333016 Protein_catabolism of Trpv4 1 0.93 0 0
86 INT333026 Regulation of Localization of Trpv4 1 0.42 0 0
87 INT234939 Positive_regulation of Negative_regulation of DSG1 1 0.23 0.74 0
88 INT234938 Regulation of Negative_regulation of DSG1 1 0.22 1.21 0
89 INT340003 Localization of HDAC7 1 0.67 1.61 0
90 INT234957 Positive_regulation of Phosphorylation of DSG1 1 0.34 0.53 0
91 INT309763 Localization of TRPV4 1 0.60 0 0
92 INT333027 Negative_regulation of Binding of Trpv4 1 0.40 0 0
93 INT158546 Regulation of Transcription of Trpv4 1 0.45 0.17 0
94 INT333017 Negative_regulation of Localization of Trpv4 1 0.40 0 0
95 INT309758 Negative_regulation of Gene_expression of TRPV4 1 0.34 0 0
96 INT277377 Phosphorylation of HDAC7 1 0.79 0.36 0
97 INT277399 Binding of HDAC7 1 0.36 1.67 0
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