GO:0007050

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Name cell cycle arrest
Categary Process
Go Slim No
Go Link GO:0007050
Unique Molecular Interactions 2459
Total Molecular Interactions 3312
Total Single Events 23139
Pain Genes Associated 133

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell cycle arrest. They are ordered first by their pain relevance and then by number of times they were reported for cell cycle arrest. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16
5 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
6 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47
7 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08
8 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
9 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
10 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
11 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
12 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5
13 INT350148 Binding of IL12A and ERAL1 1 0.21 8.23 2.26
14 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
15 INT88883 IRF6 Positive_regulation of Nfkb1 1 0.11 0.53 2.01
16 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
17 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
18 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
19 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86
20 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
21 INT346217 Braf Positive_regulation of Phosphorylation of Map2k1 1 0.22 3.23 1.72
22 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
23 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
24 INT247281 GLC1N Negative_regulation of HRAS 1 0.02 1.98 1.62
25 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56
26 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
27 INT69031 IL12A Positive_regulation of IFNA1 9 0.13 4.23 1.52
28 INT260897 CRH Positive_regulation of Localization of IL8 1 0.24 0.09 1.51
29 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
30 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
31 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49
32 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49
33 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
34 INT318491 IRF6 Positive_regulation of FPR2 1 0.10 6.14 1.44
35 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
36 INT299311 Binding of RPTOR and RICTOR 1 0.38 0.21 1.4
37 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
38 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
39 INT299281 Binding of RPTOR and MAPKAP1 1 0.23 0.21 1.3
40 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
41 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
42 INT87026 ZAK Positive_regulation of Gene_expression of IL12A 3 0.12 2.55 1.26
43 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
44 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
45 INT70046 IL12A Regulation of IL10 1 0.07 1.42 1.21
46 INT70045 IL12A Regulation of Negative_regulation of PRF1 1 0.04 1.42 1.21
47 INT70044 IL12A Regulation of PRF1 1 0.04 1.42 1.21
48 INT70034 IL12A Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
49 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
50 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
51 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
52 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
53 INT156545 Il13 Positive_regulation of Gene_expression of Il12a 1 0.27 1.56 1.13
54 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
55 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
56 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
57 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
58 INT329962 Binding of C5 and HEPACAM 1 0.03 2.25 1.06
59 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
60 INT329959 Binding of TRAF1 and HEPACAM 1 0.03 2.25 1.06
61 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04
62 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
63 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
64 INT128700 BBS9 Negative_regulation of Il12a 1 0.47 0.76 1.03
65 INT318490 IRF6 Positive_regulation of LTB4R 1 0.01 4.39 1.03
66 INT88881 Negative_regulation of IRF6 Positive_regulation of Nfkb1 1 0.09 0.27 1.03
67 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
68 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
69 INT101381 POMC Regulation of Localization of IL8 1 0.28 1.49 1.02
70 INT293014 IRF6 Positive_regulation of Localization of CA2 1 0.04 0.71 1.02
71 INT74934 Regulation of IRF6 Positive_regulation of Nfkb1 1 0.01 0.52 1.02
72 INT88887 IRF6 Positive_regulation of Transcription of Nos2 1 0.21 0.27 1.02
73 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
74 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01
75 INT148327 Binding of Pkd1 and Trpv1 1 0.52 2.23 1.01
76 INT74933 IRF6 Positive_regulation of Nfkb1 1 0.02 0.52 1.01
77 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
78 INT88884 IRF6 Regulation of Nos2 1 0.12 0.26 1
79 INT88886 IRF6 Positive_regulation of Nos2 1 0.22 0.26 1
80 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
81 INT88888 Regulation of IRF6 Positive_regulation of Nos2 1 0.20 0.26 1
82 INT110033 Adrb1 Positive_regulation of Gene_expression of Il12a 1 0.05 0 0.99
83 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
84 INT311102 IL8 Positive_regulation of CXCR7 1 0.00 1.74 0.98
85 INT311143 IL8 Positive_regulation of Cxcr1 1 0.04 1.74 0.98
86 INT133616 Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
87 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
88 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97
89 INT133615 Regulation of Map2k1 Regulation of Fadd 1 0.04 0.29 0.97
90 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
91 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
92 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
93 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95
94 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
95 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
96 INT166790 HRAS Negative_regulation of Gene_expression of PTGER1 1 0.01 1.46 0.95
97 INT182190 Binding of IL8 and CXCR4 1 0.26 1.25 0.95
98 INT73466 PTPLA Positive_regulation of Transcription of Hras1 1 0.21 0.98 0.95
99 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
100 INT182206 Binding of CXCR5 and IL8 1 0.30 1.25 0.94
101 INT41617 Sp5 Positive_regulation of Mlf1 1 0.02 0.25 0.94
102 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
103 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 0.29 0.97 0.94
104 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
105 INT182196 Binding of IL8 and CXCL13 1 0.27 1.24 0.93
106 INT227325 Binding of IRF6 and Cd14 1 0.01 2.51 0.93
107 INT94501 Il2 Positive_regulation of Gene_expression of Ifng 1 0.03 1.63 0.92
108 INT85879 Il12a Positive_regulation of Gene_expression of Ifng 1 0.20 0.89 0.92
109 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91
110 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
111 INT250976 Binding of FMOD and IL8 1 0.08 1.26 0.91
112 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
113 INT343834 Binding of CD14 and IRF6 1 0.02 2.08 0.9
114 INT121702 HRAS Negative_regulation of Positive_regulation of MMP1 1 0.06 0.2 0.9
115 INT121701 HRAS Negative_regulation of MMP1 1 0.06 0.2 0.89
116 INT121704 HRAS Negative_regulation of MMP3 1 0.06 0.19 0.89
117 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
118 INT121699 HRAS Negative_regulation of Gene_expression of MMP1 1 0.06 0.19 0.88
119 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
120 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
121 INT62956 CXCR2 Positive_regulation of IL8 1 0.30 0 0.88
122 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
123 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
124 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
125 INT116269 Binding of Myc and Mycbp2 1 0.19 0.5 0.87
126 INT343847 IRF6 Positive_regulation of TBCE 1 0.01 1.11 0.87
127 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
128 INT133176 Regulation of Mastl Negative_regulation of Il12a 1 0.01 0.24 0.86
129 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
130 INT133177 Mastl Negative_regulation of Il12a 1 0.01 0.24 0.86
131 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85
132 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
133 INT129881 Binding of Calr and Cbll1 1 0.00 0.58 0.84
134 INT120999 Binding of Oprm1 and Ifng 1 0.22 0.57 0.84
135 INT249656 tm Positive_regulation of Il12a 1 0.07 1.17 0.84
136 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
137 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
138 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
139 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
140 INT94331 IFNG Positive_regulation of CXCL10 4 0.11 1.31 0.82
141 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
142 INT113240 Il12a Regulation of Transcription of Tacr1 1 0.21 0.79 0.82
143 INT188567 IRF6 Positive_regulation of Gene_expression of CD28 1 0.05 1.28 0.82
144 INT73462 PTPLA Regulation of Gene_expression of SART1 1 0.00 0.79 0.82
145 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
146 INT87494 CALCA Positive_regulation of IL8 1 0.48 0.15 0.81
147 INT88885 IRF6 Positive_regulation of Gene_expression of Nos2 1 0.21 0.1 0.81
148 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 0.09 0.61 0.81
149 INT87492 CALCA Regulation of IL8 1 0.28 0.15 0.81
150 INT286346 IRF6 Positive_regulation of IL8 3 0.03 0.88 0.8
151 INT113238 Il12a Positive_regulation of Transcription of Tacr1 1 0.38 0.78 0.79
152 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
153 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
154 INT346234 MAP2K6 Positive_regulation of MAPK14 1 0.44 1.65 0.77
155 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
156 INT87493 Binding of CALCA and Positive_regulation of Gene_expression of IL8 1 0.52 0.18 0.76
157 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
158 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
159 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
160 INT221415 IRF6 Positive_regulation of Gene_expression of IL10 2 0.05 1.73 0.75
161 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
162 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
163 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73
164 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
165 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
166 INT14178 DHCR24 Positive_regulation of Localization of PDYN 1 0.05 0 0.72
167 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
168 INT209029 Il12b Positive_regulation of Elf1 1 0.24 0.37 0.72
169 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72
170 INT209030 Il12b Positive_regulation of Cxcl1 1 0.16 0.37 0.72
171 INT209028 Il12b Positive_regulation of Il17a 1 0.12 0.37 0.72
172 INT248244 Binding of IL8 and SDC2 1 0.02 1.57 0.72
173 INT209032 Il12b Positive_regulation of Csf2 1 0.08 0.37 0.72
174 INT146460 IFNG Positive_regulation of Gene_expression of TNFRSF10D 1 0.03 1.46 0.72
175 INT14177 DHCR24 Positive_regulation of PDYN 1 0.05 0 0.71
176 INT151679 Ifng Negative_regulation of Oas1b 1 0.12 1.24 0.71
177 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71
178 INT151676 Ifng Negative_regulation of Art2a-ps 1 0.00 1.25 0.71
179 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
180 INT267630 Il1 Regulation of Gene_expression of IL8 1 0.00 0.44 0.71
181 INT155610 FPR1 Positive_regulation of Phosphorylation of SGSM3 1 0.04 0.68 0.71
182 INT184125 Il12a Positive_regulation of Stat4 2 0.11 1.04 0.7
183 INT120037 IL8 Positive_regulation of Prap1 1 0.00 0.99 0.7
184 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
185 INT329957 Binding of STAT4 and HEPACAM 1 0.03 1.41 0.7
186 INT120019 IL8 Positive_regulation of CCL3 1 0.02 0.99 0.7
187 INT104835 IRF6 Positive_regulation of IL10 4 0.32 0.91 0.69
188 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
189 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
190 INT194618 Il17a Positive_regulation of Gene_expression of IL8 2 0.01 1.94 0.67
191 INT121966 HRAS Positive_regulation of RAC1 1 0.75 0.41 0.67
192 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
193 INT299989 PRKCA Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.67
194 INT299282 PTPN3 Negative_regulation of Positive_regulation of RPTOR 1 0.07 0.48 0.67
195 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
196 INT314560 RYBP Positive_regulation of Gene_expression of MYC 1 0.02 0.06 0.67
197 INT245299 Ccl5 Positive_regulation of Localization of IL8 1 0.11 2.87 0.66
198 INT118568 Binding of Ddit3 and Atf6 1 0.33 0.85 0.66
199 INT88194 ZAK Positive_regulation of Gene_expression of IL1B 1 0.07 0.94 0.66
200 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell cycle arrest. They are ordered first by their pain relevance and then by number of times they were reported in cell cycle arrest. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10832 Gene_expression of IL8 1050 0.78 698.72 270
2 INT12339 Localization of IL8 437 0.81 251.87 117.39
3 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62
4 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96
5 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
6 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
7 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34
8 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
9 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
10 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97
11 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2
12 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31
13 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21
14 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
15 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81
16 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
17 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51
18 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
19 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
20 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71
21 INT10835 Regulation of IL8 79 0.49 53.04 24.14
22 INT8518 Localization of Ifng 53 0.81 36.68 24.13
23 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
24 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
25 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
26 INT97798 Localization of IRF6 86 0.73 33.27 20.94
27 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85
28 INT52106 Negative_regulation of Localization of IL8 57 0.52 22.81 20.8
29 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
30 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98
31 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
32 INT19509 Localization of Ifng 55 0.78 28.25 18.67
33 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46
34 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
35 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
36 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
37 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15
38 INT93948 Negative_regulation of Gene_expression of Il12a 48 0.55 27.77 16.87
39 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
40 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
41 INT10834 Binding of IL8 65 0.48 41.66 16.53
42 INT103757 Negative_regulation of Il12a 37 0.55 21.62 16.38
43 INT52107 Transcription of IL8 63 0.72 41.66 16.06
44 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
45 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89
46 INT10360 Positive_regulation of Ifng 33 0.68 21.73 15.19
47 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
48 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
49 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36
50 INT22046 Negative_regulation of IRF6 52 0.43 25.69 14.13
51 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99
52 INT4931 Localization of IFNG 53 0.78 33.25 13.65
53 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61
54 INT75521 Positive_regulation of Positive_regulation of SGSM3 13 0.67 7.99 13.54
55 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21
56 INT99586 Binding of IRF6 60 0.36 27.87 13.2
57 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14
58 INT61624 Positive_regulation of Gene_expression of IL12A 50 0.56 33.07 13.07
59 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3
60 INT87239 Localization of Il12a 51 0.75 31.95 12.05
61 INT9160 Negative_regulation of Ifng 31 0.58 16.37 11.84
62 INT10654 Negative_regulation of SGSM3 31 0.57 12.24 11.7
63 INT67401 Gene_expression of Il12a 25 0.55 20.04 11.12
64 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
65 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91
66 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68
67 INT95565 Positive_regulation of IL12A 47 0.56 33.96 10.16
68 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
69 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
70 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
71 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
72 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25
73 INT128159 Positive_regulation of DDIT3 29 0.67 29.5 8.99
74 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
75 INT135443 Phosphorylation of Map2k1 11 0.80 2.44 8.01
76 INT171367 Phosphorylation of Map2k1 31 0.58 32.87 8
77 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
78 INT135441 Positive_regulation of Map2k1 15 0.67 6.6 7.87
79 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
80 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47
81 INT91667 Localization of IL12A 39 0.74 25.51 7.36
82 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
83 INT5326 Regulation of Ifng 12 0.55 4.56 7.19
84 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11
85 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
86 INT87644 Phosphorylation of SGSM3 12 0.80 2.08 7.04
87 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
88 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
89 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51
90 INT93137 Negative_regulation of Map2k1 17 0.42 4.51 6.49
91 INT77945 Regulation of Gene_expression of Il12a 19 0.58 6.55 6.4
92 INT76096 Positive_regulation of Gene_expression of IRF6 37 0.49 14.24 6.39
93 INT150417 Negative_regulation of Gene_expression of IRF6 20 0.41 11.48 6.28
94 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
95 INT74154 Transcription of Ifng 14 0.67 10.33 6.21
96 INT75832 Positive_regulation of Positive_regulation of IL8 30 0.70 20.77 6.05
97 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
98 INT74422 Regulation of Localization of IL8 21 0.62 10.19 5.99
99 INT15803 Regulation of IFNG 21 0.44 12.57 5.98
100 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
101 INT5186 Regulation of Ifng 11 0.45 8.78 5.9
102 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
103 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82
104 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69
105 INT83119 Negative_regulation of Gene_expression of IL12A 24 0.42 17.52 5.69
106 INT75833 Negative_regulation of Positive_regulation of IL8 15 0.53 6.69 5.59
107 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56
108 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
109 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47
110 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38
111 INT106189 Regulation of Il12a 18 0.44 12.4 5.3
112 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
113 INT75250 Negative_regulation of Positive_regulation of SGSM3 5 0.57 2.47 5.24
114 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
115 INT135440 Positive_regulation of Phosphorylation of Map2k1 5 0.49 1.32 5.22
116 INT60585 Regulation of TP53 59 0.59 54.55 5.21
117 INT80038 Positive_regulation of Gene_expression of MYC 24 0.67 13.93 5.17
118 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
119 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15
120 INT128161 Gene_expression of DDIT3 20 0.75 17.14 5.13
121 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
122 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
123 INT116150 Positive_regulation of Ddit3 26 0.67 22.58 5.01
124 INT75831 Positive_regulation of Transcription of IL8 21 0.63 13.56 4.98
125 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
126 INT62132 Regulation of Gene_expression of Ifng 12 0.62 1.28 4.77
127 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
128 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
129 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54
130 INT138779 Positive_regulation of Localization of IRF6 25 0.45 11.51 4.51
131 INT98251 Binding of IL12A 20 0.37 16.03 4.51
132 INT75530 Regulation of SGSM3 11 0.60 7.22 4.48
133 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
134 INT85126 Negative_regulation of MAP2K6 19 0.39 12.12 4.39
135 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39
136 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
137 INT118565 Gene_expression of Ddit3 35 0.75 23.62 4.32
138 INT63113 Positive_regulation of HRAS 30 0.67 22.85 4.28
139 INT20981 Binding of HRAS 42 0.48 24.49 4.23
140 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
141 INT105974 Positive_regulation of PRKAB1 43 0.67 23.47 4.16
142 INT38859 Gene_expression of SGSM3 14 0.75 12.98 4.09
143 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
144 INT106065 Negative_regulation of MAP2K1 27 0.57 12.69 3.97
145 INT80175 Positive_regulation of Gene_expression of HRAS 24 0.67 14.69 3.97
146 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
147 INT68255 Regulation of Positive_regulation of IL8 12 0.41 5.71 3.91
148 INT169475 Localization of HRAS 14 0.73 9.02 3.9
149 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89
150 INT63121 Binding of APC 29 0.41 23.02 3.8
151 INT71374 Positive_regulation of Gene_expression of Il12a 5 0.22 7.49 3.8
152 INT34054 Regulation of Gene_expression of IFNG 8 0.42 3.69 3.76
153 INT97799 Regulation of IRF6 23 0.26 6.54 3.75
154 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
155 INT144231 Gene_expression of Il12b 18 0.75 12.93 3.65
156 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65
157 INT133169 Positive_regulation of Il12b 25 0.49 13 3.64
158 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
159 INT88197 Binding of ZAK 9 0.46 6.23 3.54
160 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
161 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
162 INT119420 Phosphorylation of MAP2K6 8 0.79 4.89 3.52
163 INT102076 Regulation of DST 15 0.22 10 3.5
164 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
165 INT142483 Positive_regulation of Gene_expression of DDIT3 15 0.67 11.39 3.47
166 INT85233 Localization of SGSM3 11 0.78 10.91 3.41
167 INT174160 Binding of Il12a 19 0.24 12.61 3.4
168 INT70051 Transcription of IL12A 7 0.25 5.61 3.39
169 INT76098 Positive_regulation of Positive_regulation of IRF6 16 0.27 6.05 3.35
170 INT87027 Positive_regulation of Localization of IFNG 12 0.67 5.78 3.35
171 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
172 INT20419 Negative_regulation of Gene_expression of MYC 19 0.57 9.7 3.29
173 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
174 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28
175 INT127111 Regulation of Inhba 5 0.60 2.85 3.28
176 INT62268 Positive_regulation of Cdkn1a 33 0.67 14.12 3.26
177 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
178 INT116078 Positive_regulation of Phosphorylation of SGSM3 4 0.67 0.09 3.24
179 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
180 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
181 INT79553 Localization of Il12a 9 0.31 5.85 3.16
182 INT29929 Gene_expression of Rb1 20 0.69 5.81 3.1
183 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
184 INT38858 Positive_regulation of Gene_expression of SGSM3 5 0.49 4.15 3.05
185 INT134470 Positive_regulation of Map2k1 74 0.49 46.07 3.02
186 INT78467 Negative_regulation of IL12A 18 0.38 11.29 2.98
187 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
188 INT8103 Binding of TP53 46 0.44 40.2 2.96
189 INT181008 Negative_regulation of Localization of IRF6 13 0.14 2.32 2.96
190 INT73263 Negative_regulation of MYC 20 0.57 12.86 2.95
191 INT133174 Positive_regulation of Gene_expression of Il12b 29 0.15 13.04 2.92
192 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
193 INT36886 Transcription of Myc 6 0.69 3.16 2.86
194 INT75499 Positive_regulation of Positive_regulation of CDKN1A 12 0.60 7.28 2.84
195 INT114181 Negative_regulation of Positive_regulation of Il12a 7 0.34 3.65 2.82
196 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8
197 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
198 INT67078 Binding of Ifng 7 0.48 4.84 2.73
199 INT15197 Regulation of Gene_expression of Ifng 8 0.34 2.66 2.69
200 INT115622 Positive_regulation of Binding of IL8 7 0.44 5.79 2.69
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