GO:0007090

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Name regulation of S phase of mitotic cell cycle
Categary Process
Go Slim No
Go Link GO:0007090
Unique Molecular Interactions 60
Total Molecular Interactions 83
Total Single Events 411
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of S phase of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for regulation of S phase of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT54942 Rb1 Regulation of Gab1 1 0.02 0.39 0.59
2 INT85782 Rb1 Regulation of PRKG1 1 0.00 0.38 0.37
3 INT85778 Rb1 Regulation of Prkaca 1 0.00 0.38 0.36
4 INT85779 Rb1 Regulation of Prkcg 1 0.01 0.38 0.36
5 INT204080 HP Negative_regulation of Phosphorylation of Rb1 1 0.00 3.53 0.34
6 INT54943 Gab1 Regulation of Rb1 1 0.02 0.2 0.31
7 INT221899 Rb1 Positive_regulation of Transcription of Ccl20 1 0.01 0.62 0.16
8 INT221908 Rb1 Positive_regulation of Transcription of TNIP2 1 0.01 0.62 0.16
9 INT255258 Binding of Rb1 and Tsp1 1 0.38 0.95 0.15
10 INT310263 Rb1 Negative_regulation of Gene_expression of Tnf 1 0.07 0.97 0.15
11 INT334044 Cdt1 Regulation of Gene_expression of ALPP 1 0.04 0.72 0.12
12 INT255256 Positive_regulation of Binding of Rb1 and Tsp1 1 0.50 0.48 0.08
13 INT76862 Dynll1 Positive_regulation of Rb1 1 0.37 0.1 0.06
14 INT257867 Negative_regulation of Eif4e Positive_regulation of Rb1 1 0.05 0.54 0.06
15 INT197617 Binding of S100a6 and Rb1 1 0.03 0 0.06
16 INT298806 Binding of Hdac3 and Rb1 1 0.02 0.77 0.05
17 INT334043 Cdt1 Positive_regulation of Gene_expression of ALPP 1 0.08 0.39 0.05
18 INT273068 Binding of P2RY2 and TFAP4 1 0.01 0.27 0.05
19 INT169962 Binding of Rb1 and E2f4 1 0.25 0.56 0.04
20 INT333848 Binding of Ccna1 and Rb1 1 0.04 0.48 0.04
21 INT197587 Ppt1 Positive_regulation of Rb1 1 0.18 0 0.03
22 INT197593 Dlat Positive_regulation of Rb1 1 0.04 0 0.03
23 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0
24 INT260342 Binding of Esr1 and Rcc1 1 0.05 0.99 0
25 INT225610 Ncoa6 Regulation of Rb1 1 0.03 0.21 0
26 INT313597 Binding of BRCA2 and TOX3 1 0.11 0.7 0
27 INT301244 Rb1 Regulation of Hbp1 1 0.03 0.75 0
28 INT314742 Binding of RAD51 and Brca2 1 0.06 1.05 0
29 INT234182 Binding of BRCA2 and PALB2 1 0.41 1.43 0
30 INT339096 Ezh2 Regulation of Rcc1 1 0.02 1.1 0
31 INT305542 Binding of Rb1 and Trp53 1 0.00 0.9 0
32 INT169963 Positive_regulation of Binding of Rb1 and Rbl2 1 0.33 0.1 0
33 INT196958 Phosphorylation of Rb1 Positive_regulation of Localization of E2f1 1 0.45 0.44 0
34 INT169959 Binding of Rb1 and Rbl2 1 0.26 0.1 0
35 INT196955 Binding of E2f1 and Rb1 1 0.36 1 0
36 INT196943 E2f1 Negative_regulation of Rb1 1 0.42 0.44 0
37 INT260074 Binding of BRCA2 and PTCH1 1 0.40 0.15 0
38 INT196961 Binding of Hmga2 and Rb1 1 0.48 6.47 0
39 INT196950 Binding of Rb1 and E2f2 1 0.01 0.6 0
40 INT196947 Binding of Rb1 and Positive_regulation of Hmga2 1 0.50 0.3 0
41 INT196941 Hdac1 Negative_regulation of Rb1 1 0.27 0.44 0
42 INT196945 Rb1 Negative_regulation of Transcription of E2f1 1 0.42 0.35 0
43 INT196944 Binding of Rb1 and Hdac1 1 0.24 0.4 0
44 INT196953 Hmga2 Negative_regulation of Rb1 1 0.59 0.35 0
45 INT260072 Binding of BRCA2 and FANCC 1 0.37 0.63 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of S phase of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in regulation of S phase of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT29929 Gene_expression of Rb1 20 0.69 5.81 3.1
2 INT54938 Regulation of Rb1 6 0.44 4.41 2.69
3 INT57970 Positive_regulation of Rb1 17 0.67 7.03 2.36
4 INT57971 Regulation of Rb1 5 0.41 2.36 1.66
5 INT169907 Gene_expression of Rb1 25 0.60 21.95 1.32
6 INT41124 Negative_regulation of Rb1 11 0.44 3.17 1.22
7 INT169911 Phosphorylation of Rb1 35 0.73 18.58 0.79
8 INT147433 Gene_expression of BRCA2 7 0.62 7.02 0.79
9 INT41123 Positive_regulation of Rb1 12 0.44 3.03 0.73
10 INT169931 Localization of Rb1 6 0.70 4.79 0.65
11 INT62266 Phosphorylation of Rb1 4 0.71 2.68 0.54
12 INT93397 Negative_regulation of Phosphorylation of Rb1 1 0.51 0.32 0.48
13 INT61813 Localization of TFAP4 1 0.73 0 0.47
14 INT61812 Gene_expression of TFAP4 1 0.65 0 0.45
15 INT107294 Positive_regulation of Cdt1 3 0.24 1.52 0.43
16 INT196916 Negative_regulation of Rb1 13 0.42 14.29 0.4
17 INT41125 Positive_regulation of Localization of Rb1 2 0.38 0.78 0.39
18 INT41126 Localization of Rb1 2 0.61 0.78 0.39
19 INT196925 Positive_regulation of Gene_expression of Rb1 4 0.45 3.16 0.33
20 INT169918 Negative_regulation of Phosphorylation of Rb1 8 0.37 6.64 0.32
21 INT334041 Gene_expression of Cdt1 5 0.29 2.69 0.32
22 INT197599 Transcription of Rb1 4 0.63 0.87 0.3
23 INT173223 Negative_regulation of BRCA2 7 0.54 6.79 0.25
24 INT66230 Negative_regulation of Rcc1 1 0.28 0.75 0.24
25 INT207163 Regulation of Gene_expression of Rb1 3 0.39 1.08 0.22
26 INT260340 Gene_expression of Rcc1 4 0.58 5.36 0.21
27 INT19359 Binding of BRCA2 5 0.47 2.63 0.19
28 INT89690 Binding of Brca2 2 0.37 1.8 0.18
29 INT169930 Binding of Rb1 15 0.43 5.91 0.16
30 INT260339 Positive_regulation of Gene_expression of Rcc1 1 0.11 2.28 0.15
31 INT89691 Regulation of Brca2 1 0.23 0.56 0.13
32 INT190563 Regulation of Binding of Rb1 1 0.08 0.7 0.13
33 INT169940 Positive_regulation of Localization of Rb1 2 0.61 1.74 0.11
34 INT334040 Negative_regulation of Cdt1 1 0.16 0.56 0.09
35 INT234186 Localization of BRCA2 2 0.69 1.48 0.07
36 INT62267 Negative_regulation of Gene_expression of Rb1 1 0.12 0.82 0.07
37 INT62265 Negative_regulation of Positive_regulation of Rb1 1 0.12 0.85 0.07
38 INT334039 Positive_regulation of Gene_expression of Cdt1 1 0.26 0.78 0.07
39 INT197606 Binding of Rb1 2 0.28 0.14 0.06
40 INT199551 Regulation of Rcc1 2 0.01 2.63 0.05
41 INT334042 Regulation of Cdt1 1 0.10 0.42 0.05
42 INT260341 Positive_regulation of Rcc1 1 0.10 1.18 0.05
43 INT273080 Binding of TFAP4 1 0.01 0.27 0.05
44 INT117323 Localization of Rcc1 1 0.01 0 0.05
45 INT245909 Positive_regulation of Transcription of Rb1 1 0.05 0.49 0.04
46 INT236701 Negative_regulation of Gene_expression of Rb1 4 0.10 4.55 0.03
47 INT169945 Positive_regulation of Phosphorylation of Rb1 4 0.41 1.75 0.03
48 INT298776 Regulation of Phosphorylation of Rb1 1 0.04 0.39 0.03
49 INT167536 Positive_regulation of BRCA2 2 0.49 0.29 0
50 INT172483 Positive_regulation of TFAP4 2 0.44 0.33 0
51 INT172481 Transcription of TFAP4 2 0.66 0.58 0
52 INT234191 Positive_regulation of Localization of BRCA2 1 0.46 0.68 0
53 INT196935 Negative_regulation of Binding of Rb1 1 0.38 0.24 0
54 INT314708 Gene_expression of Brca2 1 0.41 1.75 0
55 INT197596 Negative_regulation of Transcription of Rb1 1 0.38 0.22 0
56 INT339088 Negative_regulation of Gene_expression of Rcc1 1 0.02 1.37 0
57 INT197608 Positive_regulation of Gene_expression of Rb1 1 0.44 0 0
58 INT314707 Regulation of Transcription of Brca2 1 0.27 0.56 0
59 INT196910 Positive_regulation of Binding of Rb1 1 0.45 0.81 0
60 INT172478 Positive_regulation of Transcription of TFAP4 1 0.09 0.06 0
61 INT314705 Transcription of Brca2 1 0.42 0.56 0
62 INT339093 Positive_regulation of Gene_expression of Rcc1 1 0.02 1.21 0
63 INT204055 Positive_regulation of Negative_regulation of Rb1 1 0.03 0.55 0
64 INT322778 Localization of Rcc1 1 0.61 1.43 0
65 INT173224 Regulation of BRCA2 1 0.21 1.3 0
66 INT339092 Gene_expression of Rcc1 1 0.04 6.37 0
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