GO:0007098

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Name centrosome cycle
Categary Process
Go Slim No
Go Link GO:0007098
Unique Molecular Interactions 39
Total Molecular Interactions 46
Total Single Events 261
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for centrosome cycle. They are ordered first by their pain relevance and then by number of times they were reported for centrosome cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT62849 TUBE1 Positive_regulation of Rmp1 1 0.02 0 0.65
2 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36
3 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34
4 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
5 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26
6 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26
7 INT297965 MAPK14 Negative_regulation of GADD45A 1 0.05 1 0.21
8 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14
9 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14
10 INT306274 Binding of CCNB1 and CDK1 1 0.19 0.13 0.09
11 INT320267 CCNA2 Positive_regulation of CDK1 1 0.12 1.08 0.08
12 INT194723 GADD45A Regulation of Regulation of MAPK1 1 0.06 0 0.07
13 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
14 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05
15 INT194672 GADD45A Positive_regulation of Positive_regulation of MAPK1 1 0.14 0.06 0.05
16 INT194688 PAK1 Positive_regulation of GADD45A 1 0.11 0 0.05
17 INT194677 Binding of GADD45A and MAP2K1 1 0.27 0 0.04
18 INT194726 Binding of GADD45A and MAP3K4 1 0.06 0 0.04
19 INT194741 IL18 Positive_regulation of Gene_expression of GADD45A 1 0.05 0 0.04
20 INT194679 IL12A Positive_regulation of GADD45A 1 0.04 0 0.04
21 INT194704 IL18 Positive_regulation of GADD45A 1 0.08 0 0.04
22 INT194736 Positive_regulation of MAPK1 Positive_regulation of Gene_expression of GADD45A 1 0.13 0 0.04
23 INT94159 Positive_regulation of CDK1 Negative_regulation of RB1 1 0.45 0.93 0.03
24 INT221262 Binding of BRCA1 and CD4 1 0.22 0.81 0.03
25 INT94158 CDK1 Negative_regulation of RB1 1 0.41 0.92 0.03
26 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0
27 INT234180 Binding of BRCA1 and BRIP1 1 0.33 1.37 0
28 INT194743 GADD45A Positive_regulation of Negative_regulation of MAPK1 1 0.13 0.06 0
29 INT318222 GADD45A Regulation of FOXO3 1 0.16 0.52 0
30 INT314743 Binding of RAD51 and Brca1 1 0.06 1.06 0
31 INT314740 Binding of ESR1 and Brca1 1 0.16 0.69 0
32 INT232595 Binding of BRCA1 and HEPACAM 1 0.02 0.89 0
33 INT182399 E2F2 Regulation of CDK1 1 0.00 0.09 0
34 INT182406 NFYA Regulation of CDK1 1 0.00 0.09 0
35 INT253630 Binding of HNRNPA1 and Npm1 1 0.00 0.19 0
36 INT259091 Binding of BRCA1 and LMO4 1 0.24 0.74 0
37 INT314745 Binding of TP53 and Brca1 1 0.18 1.17 0
38 INT348527 Binding of JUN and Regulation of Gene_expression of GADD45A 1 0.11 0.24 0
39 INT296162 Mcph1 Regulation of Brca1 1 0.26 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for centrosome cycle. They are ordered first by their pain relevance and then by number of times they were reported in centrosome cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17
2 INT221269 Binding of BRCA1 14 0.40 31.77 2.7
3 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53
4 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36
5 INT314186 Gene_expression of Npm1 1 0.01 1.78 1.22
6 INT124090 Gene_expression of Gadd45a 9 0.63 3.25 0.99
7 INT258791 Positive_regulation of CDK1 14 0.45 5.73 0.74
8 INT124093 Negative_regulation of Gene_expression of Gadd45a 2 0.35 1.52 0.71
9 INT62273 Gene_expression of CDK1 19 0.75 8.43 0.68
10 INT221420 Positive_regulation of Gene_expression of BRCA1 2 0.24 2.17 0.55
11 INT62272 Negative_regulation of CDK1 9 0.57 6.46 0.46
12 INT314185 Localization of Npm1 1 0.02 0.44 0.39
13 INT353457 Positive_regulation of Binding of BRCA1 1 0.09 1.69 0.34
14 INT314188 Regulation of Npm1 1 0.01 0.33 0.33
15 INT221419 Regulation of BRCA1 5 0.35 6.18 0.31
16 INT188074 Gene_expression of GADD45A 12 0.65 5.11 0.28
17 INT94166 Phosphorylation of CDK1 10 0.79 4.75 0.2
18 INT222020 Positive_regulation of Gadd45a 1 0.47 0.38 0.19
19 INT221268 Localization of BRCA1 7 0.63 4.83 0.18
20 INT119061 Negative_regulation of Gene_expression of BRCA1 4 0.51 0.85 0.18
21 INT89689 Binding of Brca1 2 0.37 2.55 0.18
22 INT173184 Regulation of CDK1 4 0.30 2.97 0.15
23 INT222021 Positive_regulation of Gene_expression of Gadd45a 3 0.47 1.29 0.14
24 INT62271 Negative_regulation of Gene_expression of CDK1 2 0.42 1.32 0.14
25 INT187590 Gene_expression of Brca1 12 0.65 4.94 0.11
26 INT208914 Regulation of Brca1 1 0.10 0.79 0.11
27 INT167436 Localization of CDK1 2 0.14 0.41 0.1
28 INT186055 Binding of CDK1 3 0.35 1.43 0.09
29 INT152987 Gene_expression of TUBE1 2 0.65 0.9 0.09
30 INT152986 Positive_regulation of Gene_expression of TUBE1 1 0.49 0.91 0.09
31 INT194803 Positive_regulation of Gene_expression of GADD45A 4 0.36 1.8 0.08
32 INT194776 Positive_regulation of GADD45A 4 0.46 2.28 0.07
33 INT174155 Negative_regulation of Brca1 4 0.36 1.77 0.07
34 INT131375 Negative_regulation of GADD45A 2 0.40 0.82 0.06
35 INT245280 Protein_catabolism of Gadd45a 1 0.26 0.4 0.06
36 INT194773 Regulation of Gene_expression of GADD45A 2 0.16 0.28 0.04
37 INT194800 Regulation of GADD45A 2 0.21 0.44 0.04
38 INT94160 Positive_regulation of Phosphorylation of CDK1 2 0.49 0.93 0.03
39 INT187589 Positive_regulation of Gene_expression of Brca1 2 0.55 1.93 0.03
40 INT94161 Negative_regulation of Phosphorylation of CDK1 1 0.41 0.93 0.03
41 INT344009 Negative_regulation of Localization of BRCA1 1 0.30 0.18 0.03
42 INT259116 Transcription of BRCA1 3 0.44 3.77 0
43 INT212457 Phosphorylation of Brca1 2 0.51 0.96 0
44 INT187580 Positive_regulation of Brca1 1 0.10 1.17 0
45 INT289866 Protein_catabolism of CDK1 1 0.46 0 0
46 INT119064 Regulation of Gene_expression of BRCA1 1 0.53 0.05 0
47 INT253599 Binding of Npm1 1 0.01 0.19 0
48 INT289863 Negative_regulation of Positive_regulation of CDK1 1 0.31 0 0
49 INT289862 Positive_regulation of Gene_expression of CDK1 1 0.26 0 0
50 INT314706 Transcription of Brca1 1 0.43 0.53 0
51 INT289869 Positive_regulation of Protein_catabolism of CDK1 1 0.26 0 0
52 INT221271 Negative_regulation of Binding of BRCA1 1 0.28 0.93 0
53 INT188072 Binding of GADD45A 1 0.36 0.4 0
54 INT334189 Regulation of Binding of BRCA1 1 0.13 0.8 0
55 INT234188 Positive_regulation of Localization of BRCA1 1 0.42 0.68 0
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