GO:0007160

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Name cell-matrix adhesion
Categary Process
Go Slim No
Go Link GO:0007160
Unique Molecular Interactions 858
Total Molecular Interactions 1168
Total Single Events 7744
Pain Genes Associated 72

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell-matrix adhesion. They are ordered first by their pain relevance and then by number of times they were reported for cell-matrix adhesion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT70946 Penk Positive_regulation of Hpse 1 0.34 0 2.65
2 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
3 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
4 INT151965 SORBS1 Positive_regulation of TRPV1 1 0.18 0 1.89
5 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
6 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
7 INT24817 Binding of POMC and VTN 8 0.42 0.39 1.71
8 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
9 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
10 INT81709 POMC Regulation of Gene_expression of ITGB2 1 0.40 0.34 1.57
11 INT81715 POMC Regulation of ITGB2 1 0.40 0.34 1.55
12 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
13 INT109958 Binding of CRH and HPSE 1 0.10 0.72 1.46
14 INT162482 Binding of Agt and Vta1 1 0.23 0 1.27
15 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
16 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
17 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
18 INT150784 ZNF398 Positive_regulation of Localization of THBS3 1 0.07 1.02 1.07
19 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
20 INT116777 Psma5 Positive_regulation of Binding of Fn1 1 0.01 1.24 1.06
21 INT70947 Penk Regulation of Hpse 1 0.20 0 0.96
22 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
23 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
24 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
25 INT61587 Agt Negative_regulation of REN 1 0.00 0.42 0.91
26 INT69424 Binding of Agt and Oprd1 1 0.14 0 0.84
27 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
28 INT140922 Btnl2 Negative_regulation of EDA 1 0.00 0.88 0.8
29 INT47143 Negative_regulation of Agt Positive_regulation of Avp 1 0.22 0 0.79
30 INT209043 Binding of Fn1 and Slc11a1 3 0.03 1.91 0.78
31 INT81716 ITGAL Regulation of ITGB2 2 0.30 1.24 0.78
32 INT172982 Binding of MUC1 and MUC4 1 0.30 2.46 0.78
33 INT158684 MAPK8 Positive_regulation of Gene_expression of BCL2L11 1 0.51 0.44 0.78
34 INT128180 Gna12 Regulation of Regulation of RHOA 1 0.00 0 0.78
35 INT81711 ITGAL Regulation of Gene_expression of ITGB2 1 0.30 0.17 0.78
36 INT113546 Binding of FN1 and ITGA3 1 0.03 2.12 0.77
37 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
38 INT113549 Binding of VTN and alphavbeta3 integrin receptor 1 0.09 2.05 0.76
39 INT178576 CNTN2 Positive_regulation of DPYD 1 0.05 2.18 0.76
40 INT178581 CNTN2 Positive_regulation of PTHLH 1 0.24 2.16 0.75
41 INT178577 CNTN2 Positive_regulation of IL2RA 1 0.03 2.16 0.75
42 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
43 INT329119 Binding of CNTN2 and CNTNAP2 1 0.08 2.41 0.73
44 INT39095 Negative_regulation of Agt Positive_regulation of Localization of Ren 1 0.38 0 0.73
45 INT101675 Bcl2l11 Regulation of Localization of Ggh 1 0.03 0 0.72
46 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
47 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68
48 INT141063 Agt Regulation of Agtr1a 1 0.28 1.18 0.68
49 INT121966 HRAS Positive_regulation of RAC1 1 0.75 0.41 0.67
50 INT47145 Penk Negative_regulation of Agt 1 0.06 0 0.66
51 INT162878 Agt Regulation of Ang 1 0.21 1.15 0.66
52 INT27526 Binding of Sdcbp and Eda 1 0.13 0 0.65
53 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
54 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64
55 INT220145 HPSE Negative_regulation of Gene_expression of CRH 1 0.01 0.92 0.64
56 INT57421 Oprd1 Regulation of Agt 1 0.29 0 0.62
57 INT142993 Serpinc1 Positive_regulation of Phosphorylation of RHOA 1 0.05 0.05 0.59
58 INT56116 Agt Positive_regulation of Lhb 1 0.15 0 0.58
59 INT56117 Agt Positive_regulation of Positive_regulation of CGA 1 0.00 0 0.56
60 INT227911 Binding of VTN and MMRN1 1 0.01 1.16 0.56
61 INT91428 CD44 Positive_regulation of Binding of MMRN1 1 0.24 0.85 0.55
62 INT73367 Agt Negative_regulation of Localization of Calca 1 0.43 0.26 0.54
63 INT69389 CNTN2 Positive_regulation of PENK 1 0.20 0.53 0.54
64 INT34459 AGT Negative_regulation of MBTPS1 1 0.01 0 0.54
65 INT150800 THBS3 Negative_regulation of SPARC 1 0.23 0.51 0.53
66 INT132438 Binding of AGT and OXTR 1 0.08 1.03 0.53
67 INT256019 Agt Negative_regulation of Lnpep 1 0.23 1.76 0.53
68 INT330544 Bcl2l11 Negative_regulation of Prkcg 1 0.03 0.38 0.52
69 INT150797 ZNF398 Positive_regulation of THBS3 1 0.07 0.5 0.52
70 INT330553 Bcl2l11 Negative_regulation of Camk2a 1 0.01 0.38 0.52
71 INT330541 Bcl2l11 Negative_regulation of Negative_regulation of Prkcg 1 0.03 0.38 0.52
72 INT150798 THBS3 Negative_regulation of TIMP2 1 0.18 0.49 0.52
73 INT330545 Bcl2l11 Negative_regulation of Trib3 1 0.00 0.38 0.52
74 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
75 INT150792 THBS3 Negative_regulation of MMP2 1 0.11 0.49 0.51
76 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
77 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
78 INT346325 Sirpa Regulation of Obfc1 1 0.00 0.41 0.48
79 INT39078 Binding of Agt and Penk 1 0.24 0.42 0.48
80 INT47144 Negative_regulation of Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
81 INT47146 Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
82 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
83 INT71178 Binding of ITGB2 and Icam1 1 0.45 1.2 0.47
84 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
85 INT39077 Agt Negative_regulation of Prss12 1 0.05 0.44 0.46
86 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
87 INT352387 Binding of CFP and HPSE 1 0.01 1.25 0.46
88 INT106001 Binding of PLAUR and VTN 2 0.23 1.5 0.45
89 INT177440 Binding of HPSE and Gnrh1 1 0.00 1.82 0.45
90 INT151958 Negative_regulation of Agt Positive_regulation of Agtrap 1 0.39 0 0.44
91 INT48383 CSF2 Regulation of Gene_expression of ITGB2 1 0.11 0.2 0.44
92 INT151959 Agt Positive_regulation of Agtrap 1 0.63 0 0.44
93 INT48389 CSF3 Regulation of Gene_expression of ITGB2 1 0.25 0.2 0.44
94 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43
95 INT184543 Agt Positive_regulation of Ccl2 1 0.16 3.18 0.43
96 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
97 INT36459 Binding of Agt and Positive_regulation of Localization of Avp 1 0.38 0.19 0.43
98 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
99 INT332248 Ccl2 Positive_regulation of Ctgf 1 0.04 1.13 0.42
100 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42
101 INT36460 Binding of Agt and Avp 1 0.28 0.16 0.4
102 INT51829 Binding of ITGA2B and ANGPTL5 1 0.35 1.08 0.4
103 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
104 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
105 INT266393 Binding of Ager and Fn1 1 0.00 0.82 0.39
106 INT266382 Binding of Col4a1 and Fn1 1 0.00 0.82 0.39
107 INT64384 Agt Negative_regulation of Son 1 0.26 0 0.39
108 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
109 INT180442 Acot1 Positive_regulation of Rhoa 1 0.08 1.03 0.38
110 INT113551 Binding of ITGA3 and VTN 1 0.02 1.03 0.38
111 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
112 INT166792 Binding of CD44 and HRAS 3 0.12 1.49 0.37
113 INT113555 Negative_regulation of Binding of FN1 and VTN 1 0.23 0.87 0.37
114 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
115 INT113559 Binding of PLAU and VTN 1 0.28 0.82 0.37
116 INT113554 Negative_regulation of Binding of PLAU and VTN 1 0.32 0.87 0.37
117 INT60817 Binding of Sstr1 and Bcl2l11 1 0.06 0 0.37
118 INT113547 Negative_regulation of Binding of PLAUR and VTN 1 0.26 0.87 0.37
119 INT39092 Agt Negative_regulation of Ren 1 0.39 0 0.37
120 INT53257 CALCRL Negative_regulation of Binding of Agt 1 0.00 0 0.36
121 INT133307 Binding of CD44 and SPP1 5 0.26 2.6 0.35
122 INT44112 Agt Regulation of Penk 1 0.08 0 0.35
123 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
124 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
125 INT4638 Binding of Agt and Adarb1 3 0.01 0 0.34
126 INT330122 Agt Positive_regulation of Gene_expression of Agtr1a 1 0.03 0.69 0.34
127 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
128 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
129 INT330119 Agt Positive_regulation of Gene_expression of Bdkrb1 1 0.37 0.63 0.34
130 INT162157 Binding of SGCG and Agt 1 0.33 0.35 0.33
131 INT206608 Binding of Ecm1 and Itgb5 1 0.02 0.41 0.33
132 INT147436 Agt Positive_regulation of Gene_expression of Ros1 1 0.02 0.5 0.33
133 INT242995 Agt Positive_regulation of Spp1 1 0.36 1.82 0.33
134 INT229363 Negative_regulation of Binding of Agt and Agtr1a 2 0.22 0.9 0.32
135 INT44127 Agt Negative_regulation of DSPP 1 0.02 0 0.32
136 INT295722 PTGER2 Positive_regulation of RAC1 1 0.02 2.14 0.32
137 INT56115 Agt Regulation of Lhb 1 0.16 0 0.32
138 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31
139 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
140 INT15828 Ambp Regulation of Negative_regulation of Fn1 1 0.03 0 0.3
141 INT93833 Binding of Fos and Srf 1 0.00 0 0.3
142 INT179844 Nid1 Regulation of Negative_regulation of Il11 1 0.19 0 0.29
143 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
144 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
145 INT179838 Col3a1 Regulation of Negative_regulation of Il11 1 0.21 0 0.29
146 INT93832 Binding of Elk1 and Srf 1 0.00 0 0.29
147 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29
148 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28
149 INT170128 Binding of ITGAL and ITGB2 2 0.04 1.6 0.28
150 INT116853 Chdh Regulation of Positive_regulation of Agt 1 0.11 0.19 0.28
151 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
152 INT45541 Agt Positive_regulation of Lnpep 1 0.03 0 0.27
153 INT343832 Positive_regulation of EDA Positive_regulation of TLR4 1 0.11 0.43 0.27
154 INT337113 Ppp1r1b Negative_regulation of Phosphorylation of Cdk5 1 0.11 0.28 0.27
155 INT45545 Agt Positive_regulation of Oxt 1 0.23 0 0.27
156 INT118848 GNA14 Positive_regulation of RAC1 1 0.01 0.14 0.26
157 INT245640 Nr3c2 Regulation of Positive_regulation of Hpse 1 0.08 0.66 0.26
158 INT126550 Agt Positive_regulation of Gene_expression of Nsfl1c 1 0.39 1.07 0.26
159 INT242991 Agt Positive_regulation of Gene_expression of Spp1 1 0.21 0.66 0.26
160 INT9528 Agt Positive_regulation of Localization of Pomc 2 0.50 0.14 0.25
161 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25
162 INT126547 Agt Positive_regulation of Nfkb1 1 0.46 0.99 0.25
163 INT343864 EDA Positive_regulation of Gene_expression of TLR4 1 0.11 0.44 0.25
164 INT126548 Negative_regulation of Agt Positive_regulation of Nfkb1 1 0.29 0.99 0.25
165 INT297258 Binding of Agt and Agtr2 1 0.23 0.7 0.25
166 INT126553 Agt Positive_regulation of Nfkb1 1 0.06 0.99 0.25
167 INT256028 Binding of Agt and Lnpep 1 0.19 1.16 0.24
168 INT41588 Binding of AGT and Lhb 1 0.00 0 0.24
169 INT316815 Ctgf Negative_regulation of Gene_expression of Sparc 1 0.47 0.64 0.24
170 INT41589 Binding of AGT and Prl 1 0.00 0 0.24
171 INT126551 Agt Positive_regulation of Gene_expression of Ptgs1 1 0.25 0.92 0.24
172 INT193029 CHRM2 Positive_regulation of RHOA 1 0.01 0.12 0.24
173 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24
174 INT140376 TGM1 Positive_regulation of Rhoa 1 0.01 0 0.24
175 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23
176 INT210798 Ihh Positive_regulation of Itgbl1 1 0.34 0 0.23
177 INT205155 Negative_regulation of Binding of CD44 and MMP9 1 0.32 1.98 0.23
178 INT269561 TMPO Positive_regulation of RHOA 1 0.22 0 0.23
179 INT292561 MAP3K5 Positive_regulation of Positive_regulation of RAC1 1 0.03 0 0.23
180 INT63420 F2 Positive_regulation of Gene_expression of ITGA2B 1 0.14 0.45 0.23
181 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
182 INT210785 Cdkn1c Positive_regulation of Itgbl1 1 0.38 0 0.23
183 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23
184 INT210794 Timp4 Positive_regulation of Itgbl1 1 0.40 0 0.23
185 INT319555 gr Positive_regulation of Positive_regulation of Hpse 1 0.09 0.11 0.22
186 INT285639 Col3a1 Regulation of Tnfrsf12a 1 0.19 0.16 0.22
187 INT273237 Cdk5 Positive_regulation of Protein_catabolism of Grin2b 1 0.45 1.31 0.22
188 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21
189 INT330051 Mapk8 Positive_regulation of Bcl2l11 1 0.13 0.46 0.21
190 INT222566 Agt Positive_regulation of Localization of Prl 1 0.08 0.23 0.21
191 INT69387 Binding of PENK and CNTN2 1 0.14 0.22 0.21
192 INT326834 Cdk5r2 Positive_regulation of Cdk5 1 0.02 0.96 0.21
193 INT229360 Agt Positive_regulation of Agtr1a 2 0.48 1.26 0.2
194 INT125153 IL1B Regulation of ITGB2 1 0.22 0.1 0.2
195 INT166791 CD44 Positive_regulation of Gene_expression of PTGER1 1 0.05 0.15 0.2
196 INT51345 Binding of Vtn and Pomc 1 0.03 0 0.2
197 INT125154 IL1B Regulation of Gene_expression of ITGB2 1 0.50 0.1 0.2
198 INT51830 Positive_regulation of Binding of ITGA2B and ANGPTL5 1 0.51 0.57 0.2
199 INT51828 Negative_regulation of Binding of ITGA2B and ANGPTL5 1 0.31 0.51 0.2
200 INT275159 Agt Positive_regulation of Phosphorylation of Stat3 1 0.04 1.44 0.2

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell-matrix adhesion. They are ordered first by their pain relevance and then by number of times they were reported in cell-matrix adhesion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
2 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
3 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
4 INT1158 Regulation of Agt 106 0.61 29.4 30.29
5 INT13415 Positive_regulation of Hpse 58 0.70 24.9 25.53
6 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
7 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
8 INT12575 Regulation of Hpse 33 0.59 17.7 18.45
9 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
10 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34
11 INT2066 Localization of Agt 56 0.80 9.95 16.25
12 INT3962 Regulation of AGT 50 0.62 20.96 13.01
13 INT63361 Gene_expression of CD44 126 0.77 71.58 12.96
14 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
15 INT4199 Binding of Agt 76 0.48 21.06 12.66
16 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
17 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93
18 INT398 Localization of AGT 45 0.78 16.97 11.54
19 INT8065 Binding of AGT 54 0.48 20.54 10.85
20 INT49474 Gene_expression of Hpse 24 0.55 20.11 10.03
21 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
22 INT386 Positive_regulation of Gene_expression of Agt 37 0.70 15.92 8.73
23 INT15723 Gene_expression of Fn1 47 0.78 37.59 8.51
24 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
25 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
26 INT15725 Positive_regulation of Fn1 17 0.67 14.93 8.03
27 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
28 INT4431 Negative_regulation of Eda 10 0.46 3.53 6.81
29 INT269144 Gene_expression of Mia1 8 0.59 11.84 6.16
30 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
31 INT39758 Gene_expression of Fn1 57 0.65 34.38 6.02
32 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
33 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84
34 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68
35 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54
36 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
37 INT10919 Positive_regulation of ITGB2 25 0.67 13.75 5.45
38 INT65554 Positive_regulation of Hpse 13 0.69 8.16 5.17
39 INT100059 Gene_expression of MUC4 30 0.75 31.58 4.95
40 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
41 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7
42 INT92682 Positive_regulation of Gene_expression of Ctgf 17 0.69 12.16 4.51
43 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
44 INT69395 Gene_expression of CNTN2 28 0.68 13.29 4.37
45 INT22973 Gene_expression of Col3a1 22 0.42 15.85 4.32
46 INT56404 Gene_expression of EDA 16 0.75 7.09 4.24
47 INT30014 Positive_regulation of HPSE 22 0.70 20.91 4.09
48 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
49 INT68978 Regulation of Positive_regulation of Hpse 6 0.45 1.88 4.02
50 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
51 INT51831 Negative_regulation of ITGA2B 20 0.57 10.59 3.91
52 INT15724 Negative_regulation of Fn1 15 0.53 5.61 3.87
53 INT70326 Positive_regulation of Gene_expression of ITGB2 24 0.67 15.42 3.86
54 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75
55 INT33739 Gene_expression of ITGA2B 25 0.75 8.19 3.6
56 INT86902 Gene_expression of Mia 9 0.68 4.34 3.54
57 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
58 INT61734 Regulation of HPSE 16 0.60 13.05 3.5
59 INT92681 Positive_regulation of Ctgf 13 0.69 9.78 3.47
60 INT15827 Regulation of Fn1 8 0.54 4.67 3.47
61 INT113604 Negative_regulation of Gene_expression of Ctgf 19 0.58 9.37 3.43
62 INT121967 Regulation of RAC1 9 0.45 6.14 3.41
63 INT13321 Negative_regulation of Hpse 11 0.56 4.64 3.39
64 INT146194 Negative_regulation of Rhoa 21 0.42 11.05 3.22
65 INT53683 Negative_regulation of Gene_expression of ITGB2 10 0.57 9.11 3.2
66 INT36032 Gene_expression of Col3a1 23 0.72 10.55 3.18
67 INT67333 Negative_regulation of ITGB2 10 0.41 6.92 3.06
68 INT128179 Gene_expression of RHOA 7 0.64 2.48 3.01
69 INT24821 Binding of VTN 14 0.47 5.83 3
70 INT146191 Gene_expression of Rhoa 32 0.67 17.63 2.92
71 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
72 INT69621 Positive_regulation of Positive_regulation of Hpse 7 0.42 4.1 2.85
73 INT96338 Gene_expression of HPSE 17 0.75 18.71 2.73
74 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
75 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
76 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
77 INT13414 Regulation of Regulation of Hpse 4 0.16 1.71 2.55
78 INT91429 Binding of CD44 34 0.41 17.67 2.51
79 INT175797 Regulation of Gene_expression of Hpse 6 0.07 6.52 2.49
80 INT140363 Negative_regulation of Rhoa 7 0.58 2.49 2.47
81 INT17857 Negative_regulation of Gene_expression of AGT 25 0.46 21.16 2.45
82 INT148071 Gene_expression of Agt 42 0.74 44.9 2.43
83 INT4270 Negative_regulation of Negative_regulation of Agt 10 0.43 1.08 2.43
84 INT140091 Gene_expression of Ctgf 26 0.78 14.21 2.39
85 INT128174 Positive_regulation of Gene_expression of RHOA 7 0.36 1.5 2.36
86 INT59287 Positive_regulation of Eda 5 0.40 1.25 2.36
87 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
88 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
89 INT146196 Localization of Rhoa 6 0.78 4.68 2.3
90 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27
91 INT162614 Positive_regulation of Mia 1 0.44 1.82 2.25
92 INT87323 Binding of ITGB2 16 0.47 9.91 2.24
93 INT74241 Positive_regulation of Gene_expression of EDA 3 0.49 4.93 2.24
94 INT35380 Binding of Fn1 8 0.35 4.84 2.23
95 INT10201 Positive_regulation of Localization of Agt 8 0.50 0.97 2.21
96 INT176088 Gene_expression of Tek 39 0.65 14.25 2.19
97 INT69789 Binding of Fn1 13 0.36 5.08 2.18
98 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17
99 INT70987 Binding of RAC1 14 0.37 12.14 2.13
100 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
101 INT12005 Negative_regulation of Localization of Agt 6 0.57 1.49 2.06
102 INT43044 Gene_expression of Eda 3 0.75 0.69 2
103 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
104 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
105 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97
106 INT79915 Positive_regulation of Agt 27 0.56 12.97 1.96
107 INT12801 Negative_regulation of Regulation of Agt 4 0.43 1.2 1.96
108 INT228129 Negative_regulation of Bcl2l11 10 0.58 11.08 1.93
109 INT43944 Negative_regulation of Positive_regulation of Agt 4 0.42 1.44 1.93
110 INT107905 Gene_expression of BCL2L11 9 0.75 7.58 1.92
111 INT69181 Positive_regulation of Col3a1 10 0.33 5.54 1.91
112 INT153684 Negative_regulation of Bcl2l11 3 0.31 1.19 1.89
113 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
114 INT126626 Positive_regulation of Rhoa 14 0.69 4.43 1.87
115 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
116 INT146193 Negative_regulation of Positive_regulation of Rhoa 3 0.42 3 1.84
117 INT158710 Negative_regulation of Binding of Cdk5 1 0.40 0 1.84
118 INT85348 Localization of RHOA 12 0.59 4.81 1.83
119 INT63029 Gene_expression of Vtn 4 0.14 2.8 1.8
120 INT91430 Positive_regulation of CD44 25 0.69 15.43 1.76
121 INT15980 Positive_regulation of Positive_regulation of Agt 6 0.50 2.99 1.76
122 INT20992 Regulation of ITGB2 11 0.37 9.04 1.73
123 INT74707 Negative_regulation of Hpse 4 0.58 2.29 1.73
124 INT168602 Negative_regulation of Itgb1 3 0.21 1.29 1.73
125 INT6598 Gene_expression of ITGA2 9 0.46 4.88 1.72
126 INT111944 Phosphorylation of VCL 3 0.73 5.23 1.72
127 INT3152 Transcription of Agt 7 0.72 5.09 1.68
128 INT86901 Negative_regulation of Mia 3 0.37 2.11 1.67
129 INT60815 Binding of Bcl2l11 2 0.27 0.95 1.67
130 INT112648 Positive_regulation of Fn1 19 0.49 13.73 1.66
131 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
132 INT33591 Negative_regulation of Positive_regulation of Hpse 6 0.32 3.42 1.63
133 INT26393 Localization of Eda 4 0.60 0.18 1.63
134 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
135 INT129492 Gene_expression of Hpse 11 0.75 6.56 1.59
136 INT74955 Negative_regulation of HPSE 6 0.57 4.75 1.57
137 INT99298 Positive_regulation of ITGA3 6 0.06 2.94 1.54
138 INT160264 Localization of Fn1 10 0.40 3.95 1.51
139 INT146190 Negative_regulation of Localization of Rhoa 4 0.42 1.64 1.5
140 INT33133 Positive_regulation of ITGA2B 13 0.67 4.09 1.44
141 INT92685 Transcription of Ctgf 7 0.72 3.92 1.44
142 INT57973 Positive_regulation of ITGB1 5 0.67 1.23 1.44
143 INT104026 Negative_regulation of Fn1 10 0.22 9.22 1.43
144 INT49402 Positive_regulation of EDA 6 0.61 4.23 1.43
145 INT34768 Negative_regulation of Negative_regulation of AGT 10 0.25 2.79 1.42
146 INT58930 Negative_regulation of RAC1 14 0.55 7.55 1.4
147 INT8067 Negative_regulation of Binding of AGT 12 0.25 10.33 1.39
148 INT71847 Positive_regulation of Positive_regulation of Col3a1 2 0.33 0.61 1.39
149 INT109222 Positive_regulation of Negative_regulation of Cdk5 2 0.50 0.23 1.39
150 INT158709 Negative_regulation of Phosphorylation of Cdk5 1 0.40 0 1.39
151 INT65553 Regulation of Hpse 6 0.27 3.89 1.37
152 INT22558 Gene_expression of COL3A1 10 0.78 7.22 1.36
153 INT56365 Regulation of Gene_expression of ITGB2 5 0.60 3.87 1.36
154 INT239215 Binding of Agt 9 0.38 6.75 1.35
155 INT214073 Binding of TSC1 9 0.37 22 1.34
156 INT55476 Negative_regulation of ITGA2 8 0.55 3.55 1.33
157 INT247903 Localization of ITGA1 1 0.06 5.69 1.32
158 INT11306 Regulation of Gene_expression of Agt 7 0.45 3.29 1.31
159 INT79840 Binding of Itga2b 4 0.16 2.51 1.28
160 INT142992 Phosphorylation of RHOA 3 0.80 0.87 1.28
161 INT148638 Protein_catabolism of Hpse 1 0.48 1.09 1.28
162 INT11241 Transcription of AGT 4 0.52 1.83 1.27
163 INT128176 Regulation of RHOA 13 0.44 4.35 1.26
164 INT198840 Transcription of EDA 1 0.58 0.97 1.26
165 INT228128 Gene_expression of Bcl2l11 31 0.67 18.31 1.25
166 INT71846 Regulation of Positive_regulation of Fn1 1 0.14 0.13 1.25
167 INT19319 Negative_regulation of Binding of Agt 9 0.42 3.42 1.24
168 INT107904 Positive_regulation of Gene_expression of BCL2L11 3 0.53 2.22 1.24
169 INT4430 Regulation of Eda 2 0.23 0.38 1.24
170 INT24819 Positive_regulation of VTN 8 0.49 3.52 1.23
171 INT269145 Positive_regulation of Gene_expression of Mia1 1 0.34 0.98 1.23
172 INT79916 Negative_regulation of Agt 14 0.47 6 1.22
173 INT111859 Regulation of Rhoa 3 0.61 0.23 1.22
174 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
175 INT303667 Regulation of BCL2L11 3 0.16 1.03 1.21
176 INT47644 Positive_regulation of Localization of AGT 4 0.45 1.24 1.2
177 INT172999 Positive_regulation of Gene_expression of MUC4 5 0.59 8.91 1.18
178 INT98595 Regulation of ILK 6 0.62 3.84 1.16
179 INT6599 Binding of ITGA2 4 0.35 3.6 1.16
180 INT28594 Positive_regulation of Transcription of Agt 2 0.47 1.3 1.15
181 INT72599 Negative_regulation of Gene_expression of ITGA2 2 0.09 1.3 1.15
182 INT115621 Positive_regulation of Binding of AGT 1 0.02 0 1.15
183 INT54044 Negative_regulation of EDA 7 0.42 2.54 1.14
184 INT158565 Regulation of Ctgf 3 0.61 3.93 1.14
185 INT63014 Gene_expression of Col5a3 1 0.00 2.13 1.13
186 INT91431 Positive_regulation of Gene_expression of CD44 18 0.69 9.25 1.12
187 INT158563 Negative_regulation of Ctgf 6 0.56 4.31 1.12
188 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12
189 INT13655 Binding of Eda 4 0.36 0.97 1.1
190 INT54043 Transcription of Fn1 3 0.61 1.59 1.1
191 INT175794 Negative_regulation of Gene_expression of Hpse 2 0.12 1.82 1.08
192 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
193 INT70329 Positive_regulation of Positive_regulation of ITGB2 3 0.67 0 1.06
194 INT96229 Localization of HPSE 3 0.20 2.76 1.05
195 INT150803 Localization of THBS3 1 0.50 1 1.05
196 INT15726 Negative_regulation of Gene_expression of Fn1 8 0.32 5.25 1.04
197 INT136817 Negative_regulation of Positive_regulation of RHOA 8 0.57 0 1.04
198 INT152404 Regulation of PKD1 2 0.45 2.02 1.04
199 INT273221 Positive_regulation of Negative_regulation of Cdk5 8 0.49 9.89 1.03
200 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03
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