GO:0007162

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Name negative regulation of cell adhesion
Categary Process
Go Slim No
Go Link GO:0007162
Unique Molecular Interactions 279
Total Molecular Interactions 331
Total Single Events 2813
Pain Genes Associated 33

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cell adhesion. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of cell adhesion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT67905 Binding of Spn and Fosl1 1 0.24 2.1 2.54
2 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
3 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
4 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
5 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
6 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
7 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53
8 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
9 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36
10 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36
11 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
12 INT134487 Positive_regulation of TGFBI Positive_regulation of Ltp 1 0.03 1.19 1.11
13 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07
14 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
15 INT73681 Regulation of KNG1 Positive_regulation of ALB 1 0.30 0.38 0.99
16 INT73680 KNG1 Positive_regulation of ALB 1 0.51 0.38 0.98
17 INT66712 Binding of BDKRB2 and KNG1 1 0.06 0.22 0.97
18 INT66711 Negative_regulation of Binding of BDKRB2 and KNG1 1 0.07 0.22 0.97
19 INT303690 KNG1 Positive_regulation of CPOX 1 0.01 0.76 0.96
20 INT66714 Negative_regulation of Binding of BDKRB1 and KNG1 1 0.13 0.22 0.96
21 INT84369 Ngf Positive_regulation of KNG1 1 0.04 0.29 0.89
22 INT96008 Binding of KNG1 and EBP 1 0.01 0.15 0.88
23 INT96010 KNG1 Positive_regulation of Binding of MTG1 1 0.32 0.15 0.88
24 INT96009 KNG1 Positive_regulation of MTG1 1 0.32 0.15 0.88
25 INT129881 Binding of Calr and Cbll1 1 0.00 0.58 0.84
26 INT192158 Binding of Mmp2 and Mmp9 1 0.21 0.94 0.83
27 INT225690 KNG1 Positive_regulation of TRPV1 1 0.42 0.7 0.83
28 INT193322 KNG1 Positive_regulation of Prh1 1 0.00 0.51 0.83
29 INT335404 Binding of Arntl and Hspg2 1 0.06 0.93 0.82
30 INT335403 Binding of Hspg2 and Npas2 1 0.04 0.93 0.82
31 INT150636 Binding of KNG1 and CD177 1 0.10 0.37 0.79
32 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
33 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
34 INT129415 KNG1 Positive_regulation of Trpv1 1 0.05 0.39 0.76
35 INT107028 KNG1 Regulation of Des 1 0.01 1.7 0.76
36 INT332699 Binding of KNG1 and TRGC1 1 0.16 3.37 0.75
37 INT121458 KNG1 Positive_regulation of Localization of Trpv1 1 0.16 0.43 0.69
38 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
39 INT348129 Bgn Regulation of Regulation of Hspg2 1 0.00 0.69 0.69
40 INT148452 Inhbe Regulation of Acvrl1 1 0.01 0.69 0.69
41 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
42 INT263049 Positive_regulation of Binding of Mmp2 and Mmp9 1 0.35 0.83 0.69
43 INT152299 Mmp2 Negative_regulation of Tsc22d1 1 0.16 0.16 0.66
44 INT152297 Mmp2 Negative_regulation of Mmp9 1 0.39 0.16 0.65
45 INT352462 Gse1 Positive_regulation of Gene_expression of Tnc 1 0.05 0.75 0.64
46 INT95546 KNG1 Positive_regulation of Ptgir 1 0.02 0.93 0.64
47 INT96472 KNG1 Positive_regulation of Gene_expression of TRPV1 1 0.01 0.22 0.64
48 INT34005 YY1 Regulation of KNG1 1 0.04 0.38 0.63
49 INT314051 THL Negative_regulation of Localization of Mmp2 1 0.14 1.1 0.62
50 INT121460 KNG1 Positive_regulation of Bdkrb2 1 0.08 0.44 0.62
51 INT121459 Bdkrb2 Positive_regulation of KNG1 1 0.09 0.44 0.62
52 INT337323 KNG1 Positive_regulation of PRKCA 1 0.15 0.17 0.62
53 INT267625 Binding of KNG1 and Klk1 2 0.21 2.23 0.61
54 INT95431 Il1a Regulation of Mmp2 1 0.48 0.25 0.61
55 INT34840 Binding of KNG1 and PDYN 1 0.01 0 0.61
56 INT95433 Mmp3 Regulation of Mmp2 1 0.17 0.24 0.6
57 INT352459 Gse1 Regulation of Gene_expression of Tnc 1 0.05 0 0.6
58 INT65285 TGFBI Negative_regulation of Pc 1 0.20 0.79 0.59
59 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58
60 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
61 INT120347 Binding of KNG1 and MYC 1 0.21 0.17 0.58
62 INT342619 Mmp2 Negative_regulation of Timp2 1 0.42 1.48 0.57
63 INT126641 Binding of KNG1 and Bdkrb2 1 0.11 0.42 0.55
64 INT164973 Binding of RASA1 and Rgs7 1 0.00 0 0.54
65 INT164972 Binding of RASA1 and Rgs8 1 0.00 0 0.53
66 INT314043 THL Negative_regulation of Mmp2 1 0.22 2.11 0.53
67 INT303721 KNG1 Positive_regulation of Bdkrb1 1 0.05 0.75 0.52
68 INT172248 Binding of KNG1 and NCOR2 1 0.02 0.19 0.52
69 INT303722 KNG1 Positive_regulation of Bdkrb2 1 0.01 0.7 0.52
70 INT33415 KNG1 Positive_regulation of GBP1 1 0.02 0.43 0.51
71 INT150921 ZNF398 Negative_regulation of Gene_expression of Mmp2 1 0.00 0.46 0.5
72 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5
73 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48
74 INT58663 Binding of KNG1 and Ugt1a2 1 0.02 0.4 0.47
75 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
76 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
77 INT138152 IL6 Positive_regulation of Transcription of Mmp2 1 0.00 0.23 0.46
78 INT138154 IL1B Positive_regulation of Transcription of Mmp2 1 0.04 0.23 0.46
79 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
80 INT65909 LAMB1 Positive_regulation of GANAB 1 0.00 0 0.45
81 INT327090 Negative_regulation of F12 Negative_regulation of Gene_expression of KNG1 1 0.00 0.51 0.45
82 INT96245 Negative_regulation of Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
83 INT96246 Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
84 INT314050 THL Negative_regulation of Transcription of Mmp2 1 0.16 0.81 0.44
85 INT201092 Binding of KNG1 and NGF 1 0.00 0.31 0.43
86 INT314042 THL Negative_regulation of Gene_expression of Mmp2 1 0.19 2.97 0.42
87 INT201120 Binding of KNG1 and Par2 1 0.00 0.3 0.42
88 INT290269 KNG1 Positive_regulation of Binding of MID1 1 0.02 1.06 0.41
89 INT290270 KNG1 Positive_regulation of MID1 1 0.02 1.06 0.41
90 INT85511 Binding of KNG1 and Bdkrb2 1 0.54 0.51 0.4
91 INT179851 Il11 Positive_regulation of Mmp2 1 0.04 0 0.38
92 INT342622 Binding of MMP14 and Mmp2 1 0.39 1.15 0.37
93 INT229222 Negative_regulation of ACE Negative_regulation of Protein_catabolism of KNG1 1 0.06 0.53 0.37
94 INT342617 Binding of Col18a1 and Mmp2 1 0.11 1.15 0.37
95 INT26552 Gene_expression of Mras Positive_regulation of Gene_expression of KNG1 1 0.03 0.07 0.36
96 INT224700 TNF Positive_regulation of Angpt1 1 0.00 0.63 0.34
97 INT136007 Binding of INSRR and KNG1 1 0.00 0.17 0.34
98 INT230855 KNG1 Regulation of NOS1 2 0.03 0.94 0.33
99 INT181899 TNF Regulation of ANGPT1 1 0.03 1.22 0.33
100 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32
101 INT35216 Binding of KNG1 and Thop1 1 0.01 0 0.32
102 INT337327 KNG1 Positive_regulation of BDKRB2 1 0.21 0.4 0.32
103 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
104 INT161435 OPA1 Positive_regulation of Gene_expression of Tnc 1 0.02 0.21 0.32
105 INT196618 Binding of KNG1 and Positive_regulation of NA 1 0.01 0.19 0.32
106 INT196623 Binding of KNG1 and Positive_regulation of DNAH8 1 0.01 0.19 0.32
107 INT170994 KNG1 Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.32
108 INT303446 Timp1 Negative_regulation of Mmp2 1 0.19 0.33 0.31
109 INT28688 Binding of Kng1 and Ctsl1 1 0.15 0 0.31
110 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31
111 INT352055 Negative_regulation of Binding of Spn and Gpr156 1 0.09 0.28 0.31
112 INT352054 Binding of Spn and Gpr156 1 0.08 0.28 0.31
113 INT66243 KNG1 Positive_regulation of Ptgis 1 0.01 0 0.3
114 INT44984 KNG1 Regulation of Ltc4s 1 0.01 0.17 0.3
115 INT196641 Binding of KNG1 and Negative_regulation of DNAH8 1 0.01 0.19 0.29
116 INT196612 Binding of KNG1 and Negative_regulation of NA 1 0.01 0.19 0.29
117 INT352452 Calca Regulation of Gene_expression of Tnc 1 0.04 0 0.28
118 INT352448 Gse1 Regulation of Tnc 1 0.03 0 0.28
119 INT352458 Dusp1 Regulation of Gene_expression of Tnc 1 0.07 0 0.28
120 INT328222 Mmp2 Regulation of Positive_regulation of Mmp13 1 0.05 0.69 0.28
121 INT196626 Binding of DNAH8 and KNG1 1 0.00 0.08 0.27
122 INT196613 Binding of KNG1 and NA 1 0.01 0.08 0.27
123 INT265830 KNG1 Positive_regulation of Localization of BGN 1 0.02 0.33 0.27
124 INT301280 Il6 Positive_regulation of Gene_expression of Acp5 1 0.04 0.37 0.26
125 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
126 INT36292 GCG Positive_regulation of MIA3 1 0.01 1.06 0.26
127 INT148223 CXCL14 Regulation of Localization of Mmp2 1 0.01 0.71 0.26
128 INT267624 Klk1 Positive_regulation of KNG1 1 0.05 0.52 0.25
129 INT295200 Hspg2 Positive_regulation of Tlr4 1 0.00 0 0.25
130 INT244687 Mmp14 Positive_regulation of Mmp2 1 0.23 0.48 0.25
131 INT267596 KNG1 Positive_regulation of Gene_expression of PLA2G6 1 0.01 0.87 0.25
132 INT311900 Acvrl1 Negative_regulation of Insrr 1 0.00 0.86 0.25
133 INT64726 Ace Negative_regulation of KNG1 1 0.01 0.26 0.25
134 INT64727 Ace Positive_regulation of KNG1 1 0.01 0.26 0.25
135 INT191500 ACE Positive_regulation of Localization of KNG1 1 0.10 0.17 0.24
136 INT239238 Ace Positive_regulation of Protein_catabolism of KNG1 1 0.01 0.46 0.24
137 INT177661 Binding of Trib3 and Myo1f 1 0.00 0.54 0.24
138 INT311908 Acvrl1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
139 INT303029 Binding of TEK and Angpt1 1 0.26 1.82 0.22
140 INT265828 ACE Regulation of Gene_expression of KNG1 1 0.32 0.83 0.22
141 INT65525 Tacr1 Regulation of Regulation of Spn 1 0.15 0.36 0.22
142 INT254281 Il4 Negative_regulation of Gene_expression of Acp5 1 0.02 0.41 0.22
143 INT281901 Binding of KNG1 and NOS3 1 0.05 0.17 0.22
144 INT332700 Binding of F12 and KNG1 1 0.15 1.05 0.21
145 INT82094 Binding of KNG1 and CLPP 1 0.03 0.42 0.21
146 INT281903 BDKRB1 Positive_regulation of KNG1 1 0.03 0.32 0.21
147 INT104702 KNG1 Negative_regulation of Anpep 1 0.11 0.47 0.19
148 INT326464 KNG1 Positive_regulation of SERPING1 1 0.19 1.53 0.18
149 INT329324 KNG1 Positive_regulation of Localization of ecs 1 0.00 1.16 0.17
150 INT220531 Atf3 Negative_regulation of Gene_expression of Mmp2 1 0.02 1.09 0.16
151 INT15525 MIA3 Negative_regulation of FFAR1 1 0.01 0.35 0.16
152 INT301121 Tgm7 Regulation of Gene_expression of Mmp2 1 0.52 2.53 0.16
153 INT85274 SGCG Positive_regulation of Mmp2 1 0.09 0.46 0.16
154 INT220515 Il10 Negative_regulation of Gene_expression of Mmp2 1 0.01 1.1 0.16
155 INT250908 Binding of Mmp2 and Tsp1 1 0.04 0.09 0.15
156 INT77159 Positive_regulation of KLK1 Positive_regulation of KNG1 1 0.04 0.28 0.15
157 INT160930 Spn Positive_regulation of Penk 1 0.14 1.18 0.15
158 INT301278 Nfatc1 Regulation of Acp5 1 0.05 0.19 0.15
159 INT250906 Binding of Mmp2 and Thbs2 1 0.06 0.09 0.15
160 INT314039 THL Negative_regulation of Binding of Mmp2 1 0.16 1.62 0.14
161 INT232018 Binding of SERPING1 and KNG1 1 0.15 0.81 0.14
162 INT304824 Binding of Rasa1 and Tnnc1 1 0.01 0 0.13
163 INT250911 Thbs2 Regulation of Mmp2 1 0.05 0.3 0.13
164 INT107635 KNG1 Regulation of Slc25a1 1 0.00 0.1 0.13
165 INT352450 Tnc Regulation of Trib3 1 0.00 0.22 0.13
166 INT107622 KNG1 Regulation of AP4B1 1 0.19 0.1 0.13
167 INT221254 Binding of KNG1 and Akt1 1 0.00 0.13 0.13
168 INT329317 ACE Regulation of Positive_regulation of KNG1 1 0.02 1.05 0.12
169 INT326380 Binding of Cxcr4 and Podxl 1 0.05 0.36 0.12
170 INT343472 Epo Positive_regulation of Gene_expression of Mmp2 1 0.15 0.62 0.12
171 INT279799 ATP6V0A2 Regulation of ERBB3 1 0.00 1.77 0.12
172 INT211996 Erbb3 Positive_regulation of Nrg1 2 0.03 0.67 0.11
173 INT229364 Ace Positive_regulation of Protein_catabolism of KNG1 1 0.02 0.86 0.11
174 INT42067 Rln1 Positive_regulation of Phosphorylation of Myo1f 1 0.11 0.1 0.1
175 INT215245 Binding of Myo1f and Chd7 1 0.00 0.64 0.1
176 INT192249 Angpt1 Positive_regulation of Localization of NOS3 1 0.01 0.46 0.09
177 INT192248 Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
178 INT196619 KNG1 Regulation of DNAH8 1 0.00 0.62 0.09
179 INT192250 Positive_regulation of Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
180 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09
181 INT196645 KNG1 Regulation of NA 1 0.00 0.62 0.09
182 INT113724 Glp1r Regulation of MIA3 2 0.00 1.22 0.08
183 INT113723 Gip Regulation of MIA3 2 0.00 1.28 0.08
184 INT137632 Rasa1 Regulation of Ednrb 1 0.05 0 0.08
185 INT231863 Binding of ARHGDIA and Akt1 1 0.02 0.23 0.07
186 INT42066 Rln1 Regulation of Phosphorylation of Myo1f 1 0.05 0.07 0.07
187 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
188 INT329121 Binding of LGI1 and ADAM22 1 0.14 0.5 0.06
189 INT311903 Acvrl1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
190 INT304331 Binding of COL5A2 and TGFBI 1 0.01 0.38 0.06
191 INT343480 Epo Positive_regulation of Mmp2 1 0.15 0.31 0.06
192 INT311910 Acvrl1 Positive_regulation of Phosphorylation of Smad1 1 0.12 0.24 0.06
193 INT238460 Binding of TGFBI and MLLT4-AS1 1 0.01 0.2 0.06
194 INT304332 Binding of FN1 and TGFBI 1 0.02 0.38 0.06
195 INT302980 Mmp2 Positive_regulation of Smpd3 1 0.29 0.78 0.05
196 INT202930 Binding of LAMB1 and Fbln5 1 0.01 0.45 0.05
197 INT138442 Lamb1 Negative_regulation of Lass1 1 0.01 0 0.05
198 INT345245 Adam9 Regulation of Adam10 1 0.09 0.18 0.05
199 INT232009 Positive_regulation of F12 Negative_regulation of Localization of KNG1 1 0.01 0.19 0.05
200 INT66856 Rln1 Positive_regulation of Localization of Mmp2 1 0.30 0 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cell adhesion. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of cell adhesion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66
2 INT7134 Localization of KNG1 127 0.79 65.73 67.97
3 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74
4 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
5 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23
6 INT3076 Regulation of KNG1 52 0.60 20.39 27.89
7 INT3167 Binding of KNG1 48 0.48 23.26 26.77
8 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
9 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
10 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42
11 INT11508 Positive_regulation of TGFBI 24 0.70 19.81 15.78
12 INT3040 Gene_expression of MIA3 81 0.24 53.61 12.62
13 INT32054 Gene_expression of Tnc 14 0.59 9.36 12.22
14 INT14204 Protein_catabolism of KNG1 41 0.96 20.94 11.47
15 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76
16 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
17 INT26551 Positive_regulation of Gene_expression of KNG1 19 0.67 11.05 7.98
18 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98
19 INT111398 Localization of Mmp2 37 0.76 23.78 7.17
20 INT3041 Positive_regulation of MIA3 34 0.56 21.11 6.49
21 INT12054 Negative_regulation of MIA3 32 0.45 23.2 6.18
22 INT123551 Regulation of Mmp2 17 0.57 11.6 6
23 INT12042 Regulation of MIA3 28 0.23 17.33 5.79
24 INT21647 Negative_regulation of Positive_regulation of KNG1 11 0.43 5.54 5.73
25 INT4938 Localization of Tnc 5 0.65 1.73 5.64
26 INT87468 Negative_regulation of Mmp2 24 0.57 10.79 5.55
27 INT11480 Positive_regulation of Localization of KNG1 15 0.30 6.39 5.5
28 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9
29 INT79194 Positive_regulation of Tnc 5 0.41 2.25 4.69
30 INT29502 Localization of Mmp2 18 0.79 3.49 4.64
31 INT49217 Positive_regulation of Positive_regulation of KNG1 7 0.41 3.64 4.18
32 INT32053 Positive_regulation of Gene_expression of Tnc 5 0.45 3.4 4.13
33 INT23317 Gene_expression of Spn 20 0.48 14.51 4.01
34 INT86293 Positive_regulation of Gene_expression of Mmp2 21 0.64 11.69 3.79
35 INT27466 Negative_regulation of Kng1 7 0.10 7.79 3.56
36 INT220078 Positive_regulation of Negative_regulation of KNG1 3 0.13 5.03 3.41
37 INT134786 Gene_expression of Adam10 17 0.68 7.61 3.29
38 INT238313 Gene_expression of Hspg2 9 0.58 3.42 3.15
39 INT65916 Gene_expression of LAMB1 13 0.55 3.09 3.06
40 INT138141 Transcription of Mmp2 10 0.64 6.52 2.99
41 INT126323 Regulation of TGFBI 6 0.59 3.17 2.9
42 INT8095 Gene_expression of ERBB3 47 0.77 24.85 2.82
43 INT17993 Negative_regulation of RASA1 8 0.41 7.34 2.62
44 INT61465 Gene_expression of Acp5 22 0.75 7.06 2.55
45 INT103603 Negative_regulation of Gene_expression of Mmp2 16 0.51 12.29 2.47
46 INT4939 Negative_regulation of Tnc 2 0.32 0.79 2.46
47 INT42140 Gene_expression of Myo1f 7 0.19 2.45 2.27
48 INT96467 Gene_expression of Lamb1 3 0.10 2.56 2.23
49 INT150640 Regulation of Binding of KNG1 3 0.35 1.31 2.2
50 INT180923 Negative_regulation of Localization of Mmp2 6 0.46 7.84 2.17
51 INT153718 Gene_expression of ANGPT1 15 0.45 10.82 2.13
52 INT8237 Positive_regulation of Kng1 16 0.69 4.41 2.12
53 INT263046 Negative_regulation of Gene_expression of Mmp2 7 0.34 5.98 2.09
54 INT43900 Gene_expression of RASA1 13 0.58 12 2.03
55 INT46332 Binding of Mmp2 10 0.34 5.63 2
56 INT161432 Negative_regulation of Gene_expression of Tnc 2 0.38 1.44 1.93
57 INT88375 Negative_regulation of Localization of KNG1 4 0.39 1.12 1.91
58 INT62349 Negative_regulation of Protein_catabolism of KNG1 8 0.42 6.47 1.86
59 INT32603 Binding of MIA3 10 0.14 7.08 1.76
60 INT152292 Regulation of Gene_expression of Mmp2 6 0.61 3.46 1.76
61 INT230668 Gene_expression of Rasa1 9 0.68 3.25 1.74
62 INT42065 Phosphorylation of Myo1f 13 0.38 2.05 1.71
63 INT65524 Regulation of Spn 8 0.21 3.82 1.7
64 INT23609 Negative_regulation of Acp5 5 0.33 1.69 1.65
65 INT126322 Negative_regulation of TGFBI 4 0.41 2.12 1.63
66 INT86294 Regulation of Gene_expression of Mmp2 3 0.60 1.12 1.62
67 INT133443 Transcription of Mmp2 8 0.69 2.48 1.61
68 INT29557 Localization of MIA3 23 0.57 6.78 1.6
69 INT74818 Transcription of KNG1 6 0.67 2.71 1.59
70 INT107132 Regulation of Localization of KNG1 2 0.22 0.96 1.55
71 INT254631 Positive_regulation of Lamb1 1 0.01 2.79 1.51
72 INT123926 Gene_expression of Angpt1 28 0.54 21.74 1.47
73 INT14916 Binding of RASA1 15 0.37 13.64 1.44
74 INT86292 Positive_regulation of Positive_regulation of Mmp2 4 0.46 3.09 1.4
75 INT310167 Gene_expression of Acvrl1 2 0.40 5.47 1.4
76 INT317979 Positive_regulation of Transcription of Mmp2 4 0.46 2.63 1.37
77 INT72943 Negative_regulation of Binding of MIA3 2 0.00 1.23 1.36
78 INT37076 Negative_regulation of Binding of KNG1 3 0.14 1.77 1.32
79 INT238074 Negative_regulation of Positive_regulation of Mmp2 4 0.34 1.79 1.31
80 INT178494 Gene_expression of Angpt1 10 0.37 9.77 1.28
81 INT53252 Gene_expression of Kng1 7 0.67 2.18 1.27
82 INT73797 Negative_regulation of Gene_expression of MIA3 14 0.10 10.65 1.25
83 INT174785 Localization of Hspg2 2 0.06 2.18 1.24
84 INT23610 Gene_expression of Acp5 4 0.51 0.96 1.23
85 INT109078 Positive_regulation of ANGPT1 7 0.22 3.08 1.21
86 INT61466 Positive_regulation of Acp5 15 0.66 10.17 1.16
87 INT133870 Positive_regulation of Gene_expression of LAMB1 2 0.35 0.41 1.15
88 INT23951 Negative_regulation of Spn 4 0.15 2.17 1.12
89 INT150638 Positive_regulation of Binding of KNG1 1 0.39 0.24 1.07
90 INT61643 Gene_expression of ACVRL1 9 0.51 9.04 1.03
91 INT42138 Binding of Myo1f 5 0.10 1.49 1.03
92 INT211723 Binding of Rasa1 3 0.07 0.85 1.03
93 INT68844 Regulation of Positive_regulation of KNG1 2 0.44 2.22 1.02
94 INT254629 Regulation of Gene_expression of Lamb1 1 0.00 0.95 1
95 INT191530 Regulation of Gene_expression of KNG1 4 0.26 0.71 0.96
96 INT180925 Positive_regulation of Localization of Mmp2 4 0.54 3.21 0.95
97 INT29501 Positive_regulation of Localization of Mmp2 3 0.60 0.42 0.94
98 INT15304 Regulation of Acp5 2 0.44 0.2 0.94
99 INT114340 Positive_regulation of Protein_catabolism of KNG1 5 0.07 2.42 0.92
100 INT29500 Regulation of Localization of Mmp2 3 0.53 0.47 0.92
101 INT61642 Binding of ACVRL1 5 0.31 7.03 0.87
102 INT27467 Localization of Kng1 2 0.76 0.78 0.87
103 INT180100 Positive_regulation of Adam10 6 0.33 2 0.84
104 INT109080 Negative_regulation of ANGPT1 8 0.14 3.17 0.82
105 INT239234 Regulation of Protein_catabolism of KNG1 2 0.09 1.06 0.82
106 INT311254 Localization of Acp5 2 0.76 3.24 0.81
107 INT311884 Negative_regulation of Acvrl1 1 0.30 2.16 0.81
108 INT335364 Negative_regulation of Transcription of Hspg2 1 0.07 0.91 0.8
109 INT152290 Regulation of Transcription of Mmp2 1 0.27 0.15 0.8
110 INT265328 Positive_regulation of Acvrl1 5 0.40 3.18 0.78
111 INT134789 Negative_regulation of Gene_expression of Adam10 1 0.30 1.22 0.78
112 INT37118 Regulation of Kng1 3 0.49 1.09 0.77
113 INT335373 Transcription of Hspg2 1 0.08 0.86 0.77
114 INT304823 Negative_regulation of Rasa1 6 0.10 0.39 0.76
115 INT159982 Negative_regulation of ERBB3 11 0.26 8.44 0.75
116 INT123773 Positive_regulation of Positive_regulation of Mmp2 2 0.17 1.83 0.75
117 INT96466 Negative_regulation of Lamb1 1 0.01 0.54 0.75
118 INT124873 Positive_regulation of Positive_regulation of Tnc 1 0.35 0.14 0.75
119 INT254633 Transcription of Lamb1 1 0.01 0.54 0.75
120 INT127487 Phosphorylation of KNG1 2 0.34 0.47 0.74
121 INT265557 Protein_catabolism of Mmp2 3 0.55 3.15 0.73
122 INT123927 Positive_regulation of Gene_expression of Angpt1 12 0.48 10.18 0.71
123 INT276176 Negative_regulation of Myo1f 4 0.12 1.85 0.71
124 INT266797 Negative_regulation of Negative_regulation of Mmp2 1 0.05 0.96 0.7
125 INT23420 Positive_regulation of Spn 8 0.49 4.81 0.69
126 INT191225 Regulation of Hspg2 3 0.06 1.04 0.68
127 INT148661 Positive_regulation of LAMB1 2 0.05 0.64 0.67
128 INT15301 Regulation of Transcription of Acp5 1 0.10 0.17 0.66
129 INT15306 Transcription of Acp5 1 0.15 0.17 0.66
130 INT37391 Regulation of Localization of MIA3 3 0.30 0.46 0.65
131 INT184185 Transcription of Kng1 1 0.05 1.66 0.62
132 INT103939 Localization of Spn 1 0.52 1.85 0.6
133 INT53251 Positive_regulation of Gene_expression of Kng1 2 0.60 0.71 0.58
134 INT55662 Negative_regulation of Negative_regulation of KNG1 4 0.36 3.45 0.57
135 INT237075 Gene_expression of Spn 5 0.42 5.18 0.56
136 INT283569 Protein_catabolism of Mmp2 5 0.77 3.25 0.56
137 INT90416 Positive_regulation of RASA1 3 0.67 1.58 0.56
138 INT327666 Regulation of Adam10 1 0.20 0 0.55
139 INT244679 Binding of Mmp2 4 0.30 3.75 0.54
140 INT27893 Negative_regulation of Regulation of MIA3 3 0.19 2.49 0.54
141 INT342614 Positive_regulation of Binding of Mmp2 1 0.46 0.6 0.54
142 INT90353 Regulation of Gene_expression of Tnc 1 0.26 0.22 0.52
143 INT124872 Regulation of Localization of Tnc 1 0.31 0.1 0.52
144 INT61464 Regulation of Acp5 2 0.59 0.72 0.51
145 INT183918 Negative_regulation of Gene_expression of Kng1 1 0.04 1.16 0.51
146 INT42139 Regulation of Myo1f 3 0.14 0.64 0.49
147 INT7248 Localization of RASA1 4 0.61 2.52 0.47
148 INT276175 Positive_regulation of Transcription of Myo1f 1 0.10 1.03 0.47
149 INT276194 Positive_regulation of Gene_expression of Myo1f 1 0.14 1.03 0.47
150 INT3039 Positive_regulation of Gene_expression of MIA3 11 0.12 7.32 0.46
151 INT276190 Transcription of Myo1f 1 0.11 1.02 0.46
152 INT145144 Positive_regulation of Negative_regulation of Mmp2 1 0.11 0.7 0.46
153 INT276191 Negative_regulation of Binding of Myo1f 1 0.09 0.05 0.46
154 INT16245 Binding of Spn 4 0.31 3.83 0.45
155 INT55893 Gene_expression of Rasa1 5 0.52 1.04 0.44
156 INT247798 Negative_regulation of Rasa1 3 0.09 1.05 0.44
157 INT230517 Localization of Myo1f 2 0.15 1.38 0.44
158 INT96909 Regulation of Angpt1 2 0.17 0.37 0.43
159 INT244683 Regulation of Positive_regulation of Mmp2 2 0.36 0.78 0.43
160 INT230653 Phosphorylation of Rasa1 3 0.55 0.6 0.42
161 INT165342 Gene_expression of TGFBI 13 0.59 5.81 0.39
162 INT35501 Positive_regulation of Myo1f 5 0.69 1.73 0.39
163 INT178497 Positive_regulation of Gene_expression of Angpt1 4 0.19 3.65 0.39
164 INT65088 Negative_regulation of Positive_regulation of Acp5 1 0.08 0 0.39
165 INT129343 Positive_regulation of Rasa1 2 0.10 1.03 0.37
166 INT311889 Negative_regulation of Gene_expression of Acvrl1 1 0.22 1.27 0.37
167 INT22786 Regulation of Tnc 1 0.23 0.18 0.37
168 INT184187 Negative_regulation of Binding of Kng1 1 0.03 1.07 0.36
169 INT184186 Binding of Kng1 1 0.03 1.06 0.36
170 INT66251 Negative_regulation of Phosphorylation of Myo1f 1 0.20 0 0.35
171 INT250036 Negative_regulation of Hspg2 2 0.05 0.57 0.32
172 INT166468 Positive_regulation of Acp5 1 0.27 0.72 0.31
173 INT246100 Positive_regulation of Gene_expression of Adam10 4 0.61 1.2 0.3
174 INT142132 Positive_regulation of Erbb3 3 0.27 0.82 0.3
175 INT65915 Regulation of Gene_expression of LAMB1 1 0.07 0 0.3
176 INT74817 Positive_regulation of Transcription of KNG1 1 0.49 0.18 0.3
177 INT21789 Positive_regulation of ERBB3 7 0.47 4.26 0.29
178 INT311895 Regulation of Positive_regulation of Acvrl1 1 0.23 0.97 0.29
179 INT146804 Positive_regulation of Gene_expression of Acp5 3 0.12 3.21 0.28
180 INT139741 Positive_regulation of Gene_expression of ACVRL1 2 0.38 1.33 0.28
181 INT55894 Positive_regulation of Gene_expression of Rasa1 1 0.47 0.19 0.28
182 INT41718 Positive_regulation of Gene_expression of Acp5 1 0.38 0.73 0.28
183 INT77678 Negative_regulation of Localization of MIA3 2 0.04 1.41 0.27
184 INT196144 Negative_regulation of Gene_expression of Acp5 2 0.14 1.01 0.26
185 INT29504 Negative_regulation of Localization of Mmp2 1 0.58 0.13 0.26
186 INT148219 Regulation of Localization of Mmp2 1 0.02 0.69 0.25
187 INT45351 Negative_regulation of ARHGDIB 1 0.47 0.56 0.25
188 INT174925 Binding of Hspg2 3 0.05 1.11 0.24
189 INT96908 Protein_catabolism of Angpt1 1 0.41 0.26 0.24
190 INT220396 Negative_regulation of Angpt1 4 0.26 1.64 0.23
191 INT181158 Positive_regulation of Hspg2 2 0.03 1.01 0.23
192 INT276203 Negative_regulation of Gene_expression of Myo1f 1 0.09 0.38 0.23
193 INT237046 Positive_regulation of Gene_expression of Spn 1 0.27 1.48 0.23
194 INT27849 Negative_regulation of Negative_regulation of MIA3 1 0.02 1.31 0.22
195 INT195576 Binding of Myo1f 6 0.06 2.79 0.21
196 INT231829 Negative_regulation of ARHGDIA 2 0.09 1.01 0.21
197 INT181791 Positive_regulation of Gene_expression of ANGPT1 1 0.29 1.27 0.2
198 INT209722 Regulation of LAMB1 1 0.00 0 0.2
199 INT291081 Positive_regulation of Protein_catabolism of Mmp2 1 0.29 0.96 0.2
200 INT291083 Negative_regulation of Protein_catabolism of Mmp2 1 0.24 0.96 0.2
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