GO:0007176

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Name regulation of epidermal growth factor-activated receptor activity
Categary Process
Go Slim No
Go Link GO:0007176
Unique Molecular Interactions 197
Total Molecular Interactions 291
Total Single Events 3188
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of epidermal growth factor-activated receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for regulation of epidermal growth factor-activated receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
2 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
3 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
4 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
5 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
6 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
7 INT159993 App Regulation of Gene_expression of Bace1 1 0.46 0.32 0.92
8 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
9 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
10 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 0.01 1.2 0.79
11 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
12 INT2700 Binding of App and Cpe 1 0.00 0 0.63
13 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
14 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
15 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
16 INT84771 Positive_regulation of Binding of App and Pag1 1 0.17 0.9 0.62
17 INT120203 Binding of App and Il1 1 0.17 1.28 0.59
18 INT120204 Binding of App and Il1f5 1 0.09 1.28 0.59
19 INT84770 Binding of App and Pag1 1 0.13 0.89 0.57
20 INT167618 Rho Regulation of App 1 0.17 0.88 0.55
21 INT167620 Rock2 Regulation of App 1 0.13 0.87 0.55
22 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
23 INT204494 Binding of App and Fmr1 1 0.54 4.39 0.54
24 INT145260 Binding of CLU and App 1 0.00 0.74 0.46
25 INT167621 Psenen Positive_regulation of App 1 0.02 0.86 0.44
26 INT167617 Bace2 Positive_regulation of App 1 0.06 0.87 0.44
27 INT167619 Protein_catabolism of Ppp2cb Positive_regulation of App 1 0.00 0.88 0.44
28 INT191610 Binding of App and Drd3 1 0.20 0.7 0.42
29 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
30 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
31 INT261790 SHC1 Positive_regulation of Slc12a5 1 0.02 0.06 0.41
32 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
33 INT79577 APP Negative_regulation of PENK 1 0.12 0.35 0.4
34 INT78121 Positive_regulation of Binding of App and 20S 1 0.23 0.61 0.4
35 INT78122 Binding of App and 20S 1 0.16 0.61 0.4
36 INT323967 Il6 Positive_regulation of Gene_expression of App 1 0.10 0.86 0.38
37 INT78854 APP Positive_regulation of Localization of IL6 1 0.14 0.79 0.37
38 INT257746 SHC1 Positive_regulation of Positive_regulation of PIK3CA 1 0.26 1.04 0.34
39 INT124376 Prodh2 Positive_regulation of App 1 0.00 0.66 0.33
40 INT124379 Prodh2 Positive_regulation of Localization of App 1 0.00 0.66 0.33
41 INT308667 Binding of Chrm1 and Positive_regulation of Binding of App 1 0.04 1.14 0.32
42 INT147434 Psenen Positive_regulation of APP 1 0.01 0.58 0.32
43 INT257743 Binding of PIK3CA and SHC1 1 0.21 1.03 0.31
44 INT68977 App Positive_regulation of Localization of Mmp9 1 0.05 0.38 0.3
45 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
46 INT319220 FSIP1 Regulation of APP 1 0.29 1.46 0.29
47 INT257744 Binding of PIK3R2 and SHC1 1 0.08 0.96 0.28
48 INT79592 Binding of APP and Reg1 1 0.01 0.16 0.27
49 INT25946 Regulation of Binding of Penk and App 1 0.18 0.19 0.27
50 INT25944 Binding of Penk and App 1 0.15 0.19 0.27
51 INT356094 Binding of App and Tg 1 0.08 0.12 0.26
52 INT139980 Negative_regulation of CTSB Negative_regulation of Gene_expression of APP 1 0.15 0.7 0.26
53 INT139981 CTSB Negative_regulation of Gene_expression of APP 1 0.11 0.7 0.26
54 INT39010 App Negative_regulation of Gene_expression of Gnrh1 1 0.05 0.07 0.26
55 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
56 INT114244 Cpox Negative_regulation of Gene_expression of APP 1 0.00 0.7 0.25
57 INT191619 Binding of App and Flna 1 0.04 0.18 0.24
58 INT70082 Binding of APP and TGM1 1 0.00 1.22 0.22
59 INT319971 App Regulation of Enpp1 1 0.02 0.72 0.21
60 INT291348 IL8 Positive_regulation of Phosphorylation of SHC1 1 0.11 1.16 0.2
61 INT146687 Regulation of Binding of App and Aph1a 1 0.16 0.58 0.19
62 INT146686 Binding of App and Aph1a 1 0.14 0.58 0.19
63 INT25945 Plat Regulation of App 1 0.15 0.25 0.17
64 INT25947 Plat Regulation of Transcription of App 1 0.15 0.25 0.17
65 INT319974 App Negative_regulation of Enpp1 1 0.02 0.58 0.16
66 INT204478 Fmr1 Regulation of Gene_expression of App 1 0.50 1.44 0.16
67 INT201744 Ngf Regulation of Transcription of App 1 0.06 0.39 0.15
68 INT201728 Ntrk1 Regulation of Transcription of App 1 0.03 0.39 0.15
69 INT319972 App Negative_regulation of Gene_expression of Enpp1 1 0.02 1.87 0.15
70 INT286476 Binding of App and Itm2b 1 0.47 5.24 0.14
71 INT94763 PSEN2 Regulation of Positive_regulation of App 1 0.11 0.72 0.14
72 INT139849 Binding of App and Bace1 7 0.41 0.85 0.13
73 INT204489 Fmr1 Regulation of App 1 0.50 1.71 0.13
74 INT220622 App Positive_regulation of Rip 2 0.14 0.24 0.12
75 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
76 INT308660 Binding of Ager and App 1 0.08 1.22 0.12
77 INT70084 Negative_regulation of Binding of APP and TGM1 1 0.00 0.61 0.11
78 INT70083 TGM1 Positive_regulation of Binding of APP 1 0.00 0.61 0.11
79 INT123101 Binding of APP and Ache 1 0.07 0.32 0.11
80 INT204477 Binding of App and Scn10a 1 0.17 0.36 0.1
81 INT139847 Binding of App and Bace2 1 0.03 0.16 0.1
82 INT139850 Binding of MBTPS1 and App 1 0.00 0.16 0.1
83 INT291351 Binding of EGFR and SHC1 1 0.05 0.57 0.1
84 INT193963 App Regulation of Gene_expression of Ps 1 0.06 0.93 0.09
85 INT356112 Binding of App and Apba1 1 0.24 0.29 0.09
86 INT262702 Bace1 Positive_regulation of Aplp2 1 0.14 0.25 0.09
87 INT262701 App Positive_regulation of Aplp2 1 0.12 0.25 0.09
88 INT262705 App Positive_regulation of Aplp1 1 0.13 0.25 0.09
89 INT124036 Binding of App and Dnahc8 1 0.03 0.14 0.09
90 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
91 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
92 INT204487 Positive_regulation of Fmr1 Regulation of Gene_expression of App 1 0.30 0.8 0.08
93 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06
94 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
95 INT198934 Binding of App and Lrp1b 2 0.27 1.62 0.05
96 INT288099 Binding of APP and App 1 0.01 1.04 0.05
97 INT356086 Negative_regulation of Binding of App and Lrp1b 1 0.30 1.42 0.05
98 INT356110 Binding of App and Slc5a7 1 0.02 0.25 0.05
99 INT193967 Binding of PSEN1 and Psen1 1 0.41 1.2 0.05
100 INT193970 Binding of PSEN1 and Psen2 1 0.36 2.06 0.05
101 INT236009 HIST2H2AA3 Positive_regulation of Protein_catabolism of APP 1 0.02 0.19 0.04
102 INT236015 HIST2H2AA3 Positive_regulation of Gene_expression of APP 1 0.02 0.95 0.04
103 INT162753 Binding of APP and Slc30a2 1 0.00 1.25 0.04
104 INT319973 App Regulation of Gene_expression of Mapk12 1 0.02 0.98 0.04
105 INT162754 Negative_regulation of Binding of APP and Slc30a2 1 0.00 1.26 0.04
106 INT356101 App Regulation of Negative_regulation of Psen1 1 0.23 0.31 0.04
107 INT198921 Binding of App and Lrp1 3 0.32 2.7 0.03
108 INT331477 PSEN2 Regulation of Gene_expression of Psen1 1 0.00 0.15 0.03
109 INT356102 Negative_regulation of Binding of App and Lrp1 1 0.32 0.71 0.03
110 INT237090 Binding of App and Bnip3l 1 0.18 1.66 0.03
111 INT354896 Binding of Psen2 and Fancd2 1 0.04 0.75 0.03
112 INT230137 OSBP Regulation of APP 1 0.59 0.15 0.03
113 INT356097 Binding of App and Apba3 1 0.12 0.12 0.03
114 INT331478 Psen1 Regulation of Gene_expression of PSEN2 1 0.00 0.15 0.03
115 INT270432 Lhb Positive_regulation of APP 1 0.03 0.51 0.03
116 INT356090 Binding of Apba2 and App 1 0.00 0.12 0.03
117 INT270431 Gnrh1 Positive_regulation of APP 1 0.06 0.51 0.03
118 INT220628 Gene_expression of Gga1 Positive_regulation of App 2 0.22 0 0
119 INT220625 Negative_regulation of Binding of App and Bace1 1 0.44 0.09 0
120 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
121 INT356108 App Positive_regulation of Positive_regulation of Lrp1 1 0.43 0.52 0
122 INT333770 Bace1 Regulation of Gene_expression of App 1 0.57 0 0
123 INT193962 Binding of Psen1 and Ncstn 1 0.13 0.08 0
124 INT225889 Binding of MET and SHC1 1 0.01 0 0
125 INT204493 App Negative_regulation of Scn10a 1 0.20 0.74 0
126 INT273289 Binding of Psen2 and Ryr2 1 0.27 4.53 0
127 INT225905 Binding of GRB2 and SHC1 1 0.00 0 0
128 INT236013 HIST2H2AA3 Regulation of Gene_expression of APP 1 0.01 0 0
129 INT204499 App Regulation of Fmr1 1 0.50 0.59 0
130 INT204492 Negative_regulation of Binding of App and Fmr1 1 0.42 0.28 0
131 INT356083 Binding of App and Notch1 1 0.02 0.2 0
132 INT356095 Lrp1 Positive_regulation of App 1 0.37 0.53 0
133 INT204502 Binding of App and RNPC3 1 0.01 0.09 0
134 INT356091 Lrp1 Positive_regulation of Positive_regulation of App 1 0.43 0.52 0
135 INT204481 App Negative_regulation of Positive_regulation of Scn10a 1 0.20 0.74 0
136 INT217398 Binding of Psen2 and Bace1 1 0.12 1.44 0
137 INT356100 Binding of Apbb1 and App 1 0.14 0.43 0
138 INT356087 Binding of App and Ncstn 1 0.17 0.07 0
139 INT230140 Gene_expression of OSBP Regulation of Localization of APP 1 0.30 0.06 0
140 INT193955 Binding of Psen1 and Psen2 1 0.37 1.64 0
141 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
142 INT198933 Binding of Apoe and App 1 0.33 0.19 0
143 INT286331 Binding of Psen1 and Ror1 1 0.27 0 0
144 INT198927 Lrp1 Regulation of App 1 0.14 0.42 0
145 INT204482 Fmr1 Negative_regulation of App 1 0.42 0.74 0
146 INT334643 Binding of APP and HM13 1 0.02 0 0
147 INT262712 Psen1 Regulation of Gene_expression of Bace1 1 0.22 0.07 0
148 INT356118 Binding of SORL1 and App 1 0.41 0.43 0
149 INT230146 Binding of APP and SORL1 1 0.20 0.17 0
150 INT356109 Rab6a Regulation of App 1 0.14 0.05 0
151 INT180123 Egfl7 Positive_regulation of App 1 0.02 0.07 0
152 INT217400 Binding of Psen1 and Bace1 1 0.17 1.43 0
153 INT286337 PSENEN Regulation of Psen1 1 0.07 0.37 0
154 INT193958 Binding of Pld1 and Psen1 1 0.17 0 0
155 INT356106 Gene_expression of Pld1 Positive_regulation of App 1 0.29 0.21 0
156 INT225629 APP Positive_regulation of Positive_regulation of nr 1 0.01 0.08 0
157 INT217396 Binding of Abca1 and App 1 0.26 0.83 0
158 INT262708 Bace1 Positive_regulation of Gene_expression of App 1 0.44 2.82 0
159 INT198915 Binding of App and Lrp8 1 0.24 0.17 0
160 INT193953 Binding of Bcl2l1 and Psen1 1 0.07 0.66 0
161 INT230139 OSBP Regulation of Phosphorylation of APP 1 0.50 0 0
162 INT193956 Binding of Psen1 and Rab6a 1 0.15 0 0
163 INT142955 Positive_regulation of Binding of APP and BACE1 1 0.48 0.5 0
164 INT262713 App Regulation of Transcription of Bace1 1 0.45 0.31 0
165 INT198925 Binding of App and Ldlr 1 0.14 0.15 0
166 INT193957 Binding of Bcl2l1 and Psen2 1 0.07 0.66 0
167 INT331479 Binding of PSEN2 and Psen1 1 0.00 0.07 0
168 INT333773 Bace1 Regulation of App 1 0.25 0 0
169 INT230143 OSBP Regulation of Gene_expression of APP 1 0.50 0.1 0
170 INT142954 Binding of APP and BACE1 1 0.37 0.5 0
171 INT204491 Ass1 Positive_regulation of App 1 0.01 0.43 0
172 INT234221 Negative_regulation of PSEN1 Negative_regulation of Gene_expression of APP 1 0.33 0.32 0
173 INT50104 Bche Regulation of Localization of App 1 0.43 0.2 0
174 INT356104 Positive_regulation of Binding of App and Lrp1 1 0.40 0.52 0
175 INT230151 OSBP Regulation of Localization of APP 1 0.50 0 0
176 INT220624 Eif1 Regulation of App 1 0.00 0.1 0
177 INT204496 App Positive_regulation of Scn10a 1 0.20 0.48 0
178 INT225627 APP Positive_regulation of nr 1 0.02 0.08 0
179 INT230149 Binding of APP and NOTCH2 1 0.32 0.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of epidermal growth factor-activated receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in regulation of epidermal growth factor-activated receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65500 Gene_expression of App 605 0.78 429.94 98.31
2 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
3 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
4 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
5 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
6 INT11625 Localization of App 98 0.78 55.46 20.86
7 INT16794 Binding of App 103 0.48 64.87 19.79
8 INT65502 Regulation of App 77 0.62 52.05 19.44
9 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
10 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
11 INT54052 Gene_expression of App 33 0.78 25.08 14.7
12 INT29745 Binding of APP 47 0.48 26.49 12.4
13 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38
14 INT65501 Regulation of Gene_expression of App 56 0.62 32.51 11.48
15 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15
16 INT41569 Regulation of APP 32 0.62 17.15 9.4
17 INT56031 Positive_regulation of App 25 0.69 13.46 7.37
18 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2
19 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
20 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
21 INT107173 Phosphorylation of App 20 0.82 12.64 5.3
22 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09
23 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06
24 INT131692 Negative_regulation of Localization of App 9 0.53 4.69 4.82
25 INT78116 Positive_regulation of Gene_expression of App 12 0.70 10.78 4.52
26 INT58003 Localization of APP 32 0.80 13.75 4.2
27 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
28 INT99821 Negative_regulation of Gene_expression of APP 20 0.42 15.21 3.94
29 INT11627 Positive_regulation of Localization of App 14 0.62 6.27 3.64
30 INT99819 Negative_regulation of Positive_regulation of APP 6 0.58 4.41 3.64
31 INT70089 Negative_regulation of Binding of APP 7 0.59 6.45 3.44
32 INT108773 Negative_regulation of Binding of App 10 0.42 7.26 2.96
33 INT54055 Regulation of Gene_expression of App 7 0.62 4.04 2.93
34 INT178772 Transcription of App 17 0.70 10.79 2.79
35 INT147429 Negative_regulation of Positive_regulation of App 8 0.40 8.73 2.78
36 INT54054 Binding of App 4 0.48 10.89 2.78
37 INT176531 Gene_expression of SHC1 3 0.67 9.5 2.62
38 INT163544 Binding of Psen1 40 0.36 15.28 2.42
39 INT162513 Regulation of Protein_catabolism of APP 5 0.51 1.79 2.36
40 INT11626 Regulation of Localization of App 4 0.45 1.51 2.34
41 INT56030 Regulation of App 8 0.62 4.06 2.32
42 INT124772 Regulation of Binding of App 6 0.45 4.92 2.09
43 INT39008 Localization of App 13 0.77 9.07 2.05
44 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
45 INT60723 Localization of Psen2 5 0.68 2.11 2.02
46 INT142774 Regulation of Phosphorylation of App 1 0.59 2.27 1.93
47 INT257755 Positive_regulation of SHC1 1 0.60 4.97 1.87
48 INT121117 Regulation of Protein_catabolism of App 10 0.62 6.41 1.78
49 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
50 INT107915 Regulation of Negative_regulation of App 6 0.45 4.47 1.76
51 INT133863 Positive_regulation of Protein_catabolism of App 12 0.59 7.53 1.52
52 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
53 INT58004 Positive_regulation of Localization of APP 5 0.46 2.1 1.5
54 INT25943 Transcription of App 5 0.53 1.79 1.44
55 INT78646 Regulation of Psen2 4 0.20 1.78 1.42
56 INT125796 Regulation of Gene_expression of APP 8 0.59 5.95 1.41
57 INT129700 Regulation of Positive_regulation of App 3 0.43 1.86 1.41
58 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
59 INT141529 Regulation of Positive_regulation of APP 3 0.44 0.31 1.34
60 INT103488 Positive_regulation of Localization of App 5 0.50 3.05 1.28
61 INT100137 Positive_regulation of Negative_regulation of App 2 0.41 1.26 1.16
62 INT135899 Regulation of Binding of APP 3 0.45 1.22 1.14
63 INT39009 Negative_regulation of App 6 0.38 3.37 1.07
64 INT257750 Positive_regulation of Gene_expression of SHC1 1 0.60 3.1 1.04
65 INT78645 Negative_regulation of Gene_expression of Psen2 1 0.14 0.13 1.01
66 INT167607 Positive_regulation of Binding of App 8 0.50 2.97 0.86
67 INT162514 Positive_regulation of Regulation of APP 1 0.41 0.37 0.86
68 INT99375 Positive_regulation of Binding of APP 3 0.61 1.63 0.83
69 INT78647 Positive_regulation of Localization of Psen2 1 0.16 0.14 0.83
70 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
71 INT118078 Phosphorylation of APP 10 0.79 2.5 0.76
72 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
73 INT193849 Positive_regulation of Gene_expression of Psen2 5 0.44 4.92 0.76
74 INT99820 Negative_regulation of Localization of APP 2 0.37 0.75 0.76
75 INT78649 Binding of Psen2 7 0.36 5.9 0.73
76 INT78648 Regulation of Binding of Psen2 1 0.14 0.2 0.73
77 INT112208 Negative_regulation of Gene_expression of App 4 0.59 1.88 0.68
78 INT25942 Regulation of Transcription of App 3 0.27 0.95 0.68
79 INT141528 Regulation of Localization of APP 2 0.52 0.4 0.67
80 INT61147 Protein_catabolism of App 3 0.60 3.76 0.63
81 INT118077 Negative_regulation of Phosphorylation of APP 1 0.07 0.74 0.61
82 INT142112 Regulation of Regulation of App 3 0.39 2.46 0.59
83 INT225462 Positive_regulation of Positive_regulation of APP 3 0.44 1.41 0.55
84 INT78117 Positive_regulation of Positive_regulation of App 4 0.48 2.6 0.51
85 INT316041 Transcription of Psen2 1 0.64 1.1 0.45
86 INT167614 Positive_regulation of Protein_catabolism of App 1 0.30 0.88 0.44
87 INT193856 Localization of Psen1 19 0.73 9.79 0.41
88 INT257756 Regulation of Gene_expression of SHC1 1 0.39 1.13 0.41
89 INT36396 Positive_regulation of Psen2 6 0.44 4.57 0.39
90 INT54056 Negative_regulation of Binding of App 2 0.37 0.99 0.32
91 INT178773 Positive_regulation of Regulation of App 2 0.49 1.01 0.32
92 INT178774 Positive_regulation of Transcription of App 2 0.49 1.17 0.31
93 INT316045 Negative_regulation of Negative_regulation of Psen1 1 0.42 1.58 0.27
94 INT181508 Regulation of Regulation of Psen1 2 0.33 0.51 0.2
95 INT286317 Positive_regulation of Transcription of Psen1 1 0.37 0.32 0.17
96 INT262690 Gene_expression of Aplp2 3 0.56 1.14 0.16
97 INT180104 Positive_regulation of Phosphorylation of App 2 0.54 0.87 0.16
98 INT286326 Regulation of Transcription of App 3 0.45 0.26 0.15
99 INT351894 Negative_regulation of SHC1 1 0.12 0.69 0.14
100 INT336359 Positive_regulation of Phosphorylation of Psen1 1 0.33 0.4 0.13
101 INT69045 Negative_regulation of Positive_regulation of App 1 0.05 0.28 0.13
102 INT336361 Phosphorylation of Psen1 1 0.54 0.34 0.13
103 INT193841 Regulation of Gene_expression of Psen2 1 0.40 1.66 0.11
104 INT142958 Positive_regulation of Protein_catabolism of APP 3 0.55 2.04 0.1
105 INT191353 Localization of SHC1 2 0.73 0.75 0.1
106 INT291370 Phosphorylation of SHC1 1 0.14 0.57 0.1
107 INT273285 Negative_regulation of Localization of Psen1 1 0.36 0.99 0.09
108 INT39007 Negative_regulation of Localization of App 3 0.10 0.94 0.08
109 INT193862 Positive_regulation of Positive_regulation of Psen1 3 0.49 0.9 0.08
110 INT193872 Positive_regulation of Localization of Psen1 3 0.49 1.39 0.08
111 INT262676 Positive_regulation of Gene_expression of Aplp2 1 0.29 0.24 0.08
112 INT193890 Regulation of Positive_regulation of Psen1 1 0.44 0.66 0.08
113 INT193831 Localization of Aplp2 2 0.42 1.85 0.06
114 INT193852 Positive_regulation of Localization of Aplp2 1 0.23 0.81 0.06
115 INT193859 Negative_regulation of Binding of Psen1 3 0.42 1.85 0.05
116 INT331406 Negative_regulation of Regulation of Psen1 1 0.04 0.09 0.05
117 INT193865 Protein_catabolism of Psen1 10 0.97 0.37 0.04
118 INT188125 Binding of Aplp2 2 0.22 0.64 0.04
119 INT180116 Negative_regulation of Transcription of App 1 0.38 0 0.04
120 INT182830 Negative_regulation of Protein_catabolism of APP 2 0.35 2.09 0.03
121 INT255657 Negative_regulation of Protein_catabolism of App 1 0.20 1.07 0.03
122 INT351386 Negative_regulation of Phosphorylation of App 1 0.42 0.82 0.03
123 INT50103 Regulation of Localization of App 2 0.26 0.2 0
124 INT234255 Transcription of APP 2 0.49 0.98 0
125 INT191352 Regulation of SHC1 2 0.14 1.46 0
126 INT286327 Regulation of Binding of Psen1 1 0.33 0.16 0
127 INT286323 Negative_regulation of Protein_catabolism of App 1 0.11 0.54 0
128 INT193886 Regulation of Protein_catabolism of Psen1 1 0.44 0.06 0
129 INT331407 Negative_regulation of Transcription of Psen1 1 0.04 0.08 0
130 INT176532 Binding of SHC1 1 0.36 1.3 0
131 INT354892 Negative_regulation of Psen2 1 0.37 0.95 0
132 INT193844 Positive_regulation of Protein_catabolism of Psen1 1 0.49 0.05 0
133 INT236037 Positive_regulation of Phosphorylation of APP 1 0.48 0.14 0
134 INT190556 Regulation of Aplp2 1 0.10 0.33 0
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