GO:0007179

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Name transforming growth factor beta receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0007179
Unique Molecular Interactions 2433
Total Molecular Interactions 3241
Total Single Events 36034
Pain Genes Associated 80

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for transforming growth factor beta receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for transforming growth factor beta receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
2 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49
3 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
4 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
5 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
6 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
7 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
8 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
9 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
10 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
11 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
12 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
13 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
14 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
15 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
16 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
17 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
18 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
19 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 0.69 0.5 2.18
20 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
21 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
22 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
23 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
24 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
25 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
26 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
27 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
28 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98
29 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
30 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
31 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
32 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
33 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
34 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
35 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8
36 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
37 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
38 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
39 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
40 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76
41 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
42 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
43 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
44 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
45 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69
46 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
47 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
48 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
49 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
50 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
51 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
52 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
53 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
54 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54
55 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
56 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
57 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
58 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
59 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
60 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
61 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44
62 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41
63 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
64 INT108583 Binding of Vip and Fos 1 0.36 0 1.39
65 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
66 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
67 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
68 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
69 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
70 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
71 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32
72 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
73 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
74 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
75 INT66428 Dcc Positive_regulation of Fos 2 0.05 0.39 1.29
76 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27
77 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
78 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
79 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 1 0.47 0.88 1.26
80 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
81 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
82 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
83 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
84 INT71443 CSAD Positive_regulation of Gene_expression of Fos 1 0.58 0.81 1.23
85 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23
86 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
87 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
88 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
89 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22
90 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
91 INT109380 Binding of Adarb1 and Fos 1 0.02 0.38 1.19
92 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
93 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
94 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
95 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
96 INT73075 Adarb1 Regulation of Fos 1 0.01 0.07 1.18
97 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
98 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 0.34 0.14 1.16
99 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
100 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14
101 INT123454 CNR1 Regulation of Fos 1 0.00 0.06 1.12
102 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
103 INT112608 DNAJC15 Regulation of Gene_expression of Fos 1 0.02 0.14 1.12
104 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
105 INT123455 CNR1 Regulation of Positive_regulation of Fos 1 0.00 0.06 1.12
106 INT143941 Il1f5 Negative_regulation of Gene_expression of Fos 1 0.00 1.03 1.11
107 INT102421 POMC Regulation of Gene_expression of Fos 1 0.12 0.34 1.11
108 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09
109 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09
110 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
111 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
112 INT132701 Adarb1 Negative_regulation of Gene_expression of Fos 1 0.01 0.73 1.07
113 INT107938 POMC Positive_regulation of Gene_expression of TGFBR2 1 0.42 1.09 1.07
114 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
115 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
116 INT100564 CRX Positive_regulation of Fos 1 0.04 0.89 1.06
117 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
118 INT119888 Binding of Creb1 and Usf1 1 0.18 0.15 1.05
119 INT270680 Fos Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.03 0.39 1.05
120 INT214875 Ap3d1 Negative_regulation of Gene_expression of Fos 1 0.00 0.39 1.04
121 INT146097 Positive_regulation of Binding of Rgs9 and Arrb2 1 0.28 0 1.04
122 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04
123 INT146518 Tmem132a Positive_regulation of Gene_expression of Fos 1 0.68 0.06 1.04
124 INT134213 CRH Positive_regulation of Gene_expression of ENG 1 0.13 0.61 1.03
125 INT146098 Binding of Rgs9 and Arrb2 1 0.19 0 1.03
126 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
127 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
128 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02
129 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
130 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
131 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
132 INT143177 Apcs Negative_regulation of Gene_expression of Fos 1 0.02 0.36 1.01
133 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
134 INT11251 Negative_regulation of Cck Positive_regulation of Fos 2 0.48 0 1
135 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
136 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
137 INT143916 Arrb2 Regulation of Rbm39 1 0.04 0.18 1
138 INT71319 Binding of Penk and Fos 3 0.40 0.15 0.99
139 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
140 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98
141 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
142 INT94206 SP5 Regulation of Gene_expression of FOS 1 0.22 0.7 0.98
143 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97
144 INT145823 Ngf Positive_regulation of Fos 1 0.52 0.95 0.97
145 INT281375 Il1r1 Negative_regulation of Gene_expression of Fos 1 0.47 0.61 0.97
146 INT145824 Negative_regulation of Ngf Positive_regulation of Fos 1 0.48 0.95 0.97
147 INT93234 Negative_regulation of Pde4b Negative_regulation of Gene_expression of Fos 1 0.41 0.1 0.96
148 INT281380 Fos Negative_regulation of Gene_expression of FSCN1 1 0.07 0.4 0.96
149 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96
150 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96
151 INT103833 Sp5 Positive_regulation of Fos 1 0.51 0 0.96
152 INT155044 Negative_regulation of Ceacam3 Negative_regulation of Gene_expression of Fos 1 0.61 0 0.95
153 INT135585 CSF2 Regulation of CCL2 1 0.13 2.51 0.95
154 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
155 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
156 INT155043 Vta1 Regulation of Gene_expression of Fos 1 0.08 0 0.95
157 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
158 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
159 INT80601 Akr1d1 Regulation of Positive_regulation of Fos 1 0.06 0 0.94
160 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
161 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
162 INT48148 Fos Positive_regulation of Gene_expression of Pdyn 1 0.21 0 0.94
163 INT186568 Hpcl1 Regulation of Gene_expression of Fos 1 0.22 0.07 0.94
164 INT281377 FSCN1 Positive_regulation of Gene_expression of Fos 1 0.08 0.49 0.93
165 INT89514 Pnoc Regulation of Gene_expression of Fos 1 0.47 0.98 0.93
166 INT120380 Cnr1 Positive_regulation of Gene_expression of Fos 1 0.31 0.45 0.93
167 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
168 INT143578 Olr404 Negative_regulation of Positive_regulation of Fos 1 0.01 0.39 0.93
169 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
170 INT129003 Ccl2 Positive_regulation of ANTXRL 1 0.00 0.68 0.92
171 INT86350 Negative_regulation of Adarb1 Negative_regulation of Positive_regulation of Fos 1 0.04 0.8 0.92
172 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
173 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92
174 INT86349 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Fos 1 0.42 0.8 0.92
175 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
176 INT32187 Binding of ENG and Negative_regulation of Localization of LH 1 0.01 0 0.91
177 INT66536 Il1a Regulation of Gene_expression of Fos 1 0.59 0 0.91
178 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91
179 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
180 INT166221 Negative_regulation of Gls Negative_regulation of Gene_expression of Fos 1 0.50 0.37 0.9
181 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9
182 INT309140 Dlat Positive_regulation of Creb1 1 0.06 1.1 0.9
183 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
184 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
185 INT164677 Ngf Positive_regulation of Gene_expression of Fos 1 0.52 0.08 0.89
186 INT142128 Nrgn Regulation of Creb1 1 0.38 0.25 0.89
187 INT242621 Gdnf Positive_regulation of Gene_expression of Scn11a 1 0.05 0.12 0.88
188 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
189 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
190 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
191 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
192 INT87416 SNORD50A Regulation of Positive_regulation of Fos 1 0.13 0 0.87
193 INT73653 Binding of Creb1 and Fos 1 0.40 1.49 0.87
194 INT161308 POMC Negative_regulation of Positive_regulation of JUN 1 0.12 0.27 0.86
195 INT124878 Gnat3 Negative_regulation of Gene_expression of FOS 1 0.09 0.16 0.85
196 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
197 INT60719 Insrr Positive_regulation of Fos 1 0.03 1.23 0.84
198 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
199 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
200 INT302379 Crp Positive_regulation of Gene_expression of Ccl2 1 0.10 4.58 0.84

Single Events

The table below shows the top 100 pain related interactions that have been reported for transforming growth factor beta receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in transforming growth factor beta receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
3 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
4 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
5 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54
6 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
7 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
8 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
9 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
10 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
11 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05
12 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
13 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
14 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
15 INT5587 Regulation of Fos 191 0.62 40.81 99.7
16 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31
17 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
18 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
19 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26
20 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
21 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
22 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
23 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
24 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77
25 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39
26 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
27 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
28 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
29 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
30 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6
31 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
32 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
33 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
34 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
35 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
36 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6
37 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69
38 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
39 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
40 INT65698 Localization of CCL2 118 0.81 77.54 32.69
41 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
42 INT6053 Transcription of Fos 107 0.72 20.97 31.88
43 INT48890 Gene_expression of Gdnf 91 0.77 28.62 31.49
44 INT94388 Gene_expression of GDF15 124 0.77 79.48 31.42
45 INT47764 Binding of Jun 106 0.48 22.62 31.39
46 INT6058 Localization of Fos 73 0.81 16.7 30.84
47 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25
48 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
49 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
50 INT82882 Localization of Ccl2 61 0.80 41.96 28
51 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
52 INT10799 Localization of ENG 63 0.78 18.67 27.28
53 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
54 INT5378 Regulation of Gene_expression of Fos 47 0.60 14.47 26.41
55 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95
56 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64
57 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28
58 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
59 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
60 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
61 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
62 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05
63 INT5586 Binding of Fos 47 0.48 12.7 21.33
64 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52
65 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58
66 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
67 INT101988 Positive_regulation of GDF15 71 0.69 51.03 18.56
68 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
69 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
70 INT11275 Regulation of Fos 37 0.60 5.79 18.18
71 INT62577 Negative_regulation of Creb1 55 0.59 19.68 18.1
72 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
73 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06
74 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
75 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85
76 INT8526 Negative_regulation of Positive_regulation of Fos 26 0.59 5.99 17.52
77 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
78 INT102023 Regulation of Creb1 51 0.62 16.29 16.71
79 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
80 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
81 INT94390 Positive_regulation of Gene_expression of GDF15 67 0.69 45.5 14.74
82 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
83 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
84 INT7674 Regulation of ENG 42 0.30 11.41 14.44
85 INT17593 Regulation of Jun 37 0.60 5.5 14.35
86 INT107248 Negative_regulation of Gene_expression of Creb1 26 0.58 9.24 13.41
87 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
88 INT102897 Positive_regulation of Gene_expression of Gdnf 34 0.69 11.13 13.28
89 INT16713 Binding of Creb1 53 0.48 20.24 13.06
90 INT15246 Regulation of FOS 32 0.60 15.34 12.94
91 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55
92 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06
93 INT94981 Gene_expression of Arrb2 12 0.70 2.11 11.75
94 INT6051 Positive_regulation of Transcription of Fos 27 0.69 6.3 11.48
95 INT70816 Negative_regulation of Fos 32 0.58 13 11.18
96 INT52233 Transcription of Jun 37 0.66 6.39 11.15
97 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
98 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
99 INT52657 Phosphorylation of Fos 20 0.80 6.36 10.64
100 INT62576 Transcription of Creb1 34 0.69 16.97 10.6
101 INT82950 Positive_regulation of Gdnf 36 0.51 11.72 10.5
102 INT109280 Negative_regulation of Phosphorylation of Creb1 29 0.59 11.81 10.37
103 INT60198 Binding of JUN 54 0.48 11.56 10.27
104 INT17592 Positive_regulation of Regulation of Fos 21 0.67 3.54 10.07
105 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
106 INT83450 Positive_regulation of Localization of CCL2 28 0.70 22.14 9.83
107 INT106200 Binding of Ccl2 22 0.42 16.7 9.75
108 INT8527 Positive_regulation of Positive_regulation of Fos 20 0.70 6.87 9.62
109 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45
110 INT140224 Localization of Ccl2 32 0.72 26.91 9.39
111 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18
112 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14
113 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08
114 INT109279 Regulation of Phosphorylation of Creb1 14 0.62 4.06 8.96
115 INT61264 Regulation of Jun 36 0.61 18.42 8.71
116 INT47769 Phosphorylation of Fos 20 0.61 3.03 8.68
117 INT7673 Negative_regulation of ENG 31 0.42 7.9 8.61
118 INT64815 Binding of Jun 49 0.48 21.47 8.59
119 INT17333 Positive_regulation of Positive_regulation of FOS 17 0.67 6.06 8.4
120 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
121 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29
122 INT93673 Transcription of Creb1 19 0.66 9.27 8.26
123 INT53975 Positive_regulation of Binding of Jun 28 0.70 4.67 8.16
124 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91
125 INT64816 Transcription of Jun 31 0.69 16.01 7.64
126 INT47848 Negative_regulation of Positive_regulation of FOS 14 0.57 3.78 7.63
127 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61
128 INT10344 Localization of Jun 23 0.73 6.36 7.46
129 INT116619 Positive_regulation of Positive_regulation of Creb1 25 0.69 8.32 7.3
130 INT86867 Regulation of CREB1 15 0.46 4.95 7.28
131 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
132 INT82881 Regulation of Ccl2 19 0.57 15.29 7.19
133 INT75497 Regulation of JUN 28 0.61 11.04 7.09
134 INT106330 Regulation of Positive_regulation of Creb1 11 0.56 5.57 7.06
135 INT60196 Binding of FOS 33 0.47 13.11 6.95
136 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
137 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
138 INT53491 Negative_regulation of Jun 28 0.57 14.2 6.9
139 INT47817 Positive_regulation of Positive_regulation of Jun 21 0.66 3.7 6.83
140 INT81493 Transcription of CCL2 20 0.65 13.63 6.78
141 INT100079 Positive_regulation of Gene_expression of Arrb2 7 0.63 2.26 6.77
142 INT114642 Negative_regulation of Positive_regulation of Creb1 12 0.57 2.32 6.75
143 INT68653 Negative_regulation of JUN 34 0.58 14.27 6.56
144 INT120895 Binding of CCL2 22 0.37 15.86 6.55
145 INT23375 Binding of ENG 17 0.47 6.02 6.46
146 INT94979 Regulation of Arrb2 6 0.54 0.51 6.45
147 INT5847 Transcription of FOS 31 0.69 11.11 6.41
148 INT47765 Negative_regulation of Binding of Jun 21 0.43 5.05 6.38
149 INT80447 Negative_regulation of ARRB2 5 0.39 3.12 6.3
150 INT92504 Negative_regulation of Ccl2 17 0.43 8.98 6.29
151 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
152 INT94986 Positive_regulation of Arrb2 5 0.61 1.3 6.24
153 INT92971 Binding of Creb1 31 0.47 11.3 6.22
154 INT4629 Regulation of Fshb 12 0.49 1.93 5.95
155 INT73649 Phosphorylation of Jun 28 0.80 11.01 5.87
156 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84
157 INT8525 Regulation of Positive_regulation of Fos 9 0.60 4.04 5.75
158 INT115087 Negative_regulation of Gdnf 10 0.51 5.78 5.73
159 INT61986 Localization of Creb1 16 0.69 2.12 5.66
160 INT83290 Regulation of Gene_expression of Ccl2 8 0.59 9.06 5.56
161 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
162 INT140223 Regulation of Ccl2 15 0.45 13.1 5.41
163 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36
164 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
165 INT93484 Negative_regulation of Positive_regulation of Jun 30 0.58 9.31 5.18
166 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
167 INT85685 Gene_expression of Arrb2 5 0.74 0.66 5.13
168 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
169 INT84561 Binding of COL1A2 18 0.47 11.76 5.09
170 INT102019 Regulation of Gene_expression of Creb1 14 0.61 5.27 5.08
171 INT102202 Negative_regulation of Positive_regulation of Creb1 11 0.58 4.55 4.99
172 INT161220 Binding of Ccl2 17 0.46 17.63 4.94
173 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78
174 INT85681 Negative_regulation of Arrb2 5 0.47 0.79 4.71
175 INT103073 Positive_regulation of Positive_regulation of Ccl2 10 0.50 6.74 4.7
176 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
177 INT78626 Regulation of Gdnf 7 0.45 3.3 4.64
178 INT96851 Negative_regulation of Localization of CCL2 14 0.53 5.98 4.57
179 INT54911 Localization of FOS 20 0.78 3.27 4.56
180 INT121866 Localization of Creb1 13 0.73 1.95 4.48
181 INT47766 Transcription of Fos 25 0.69 8.78 4.42
182 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
183 INT108935 Transcription of Arrb2 5 0.59 0.5 4.38
184 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
185 INT22973 Gene_expression of Col3a1 22 0.42 15.85 4.32
186 INT92797 Regulation of Arrb2 4 0.44 0.81 4.28
187 INT94985 Regulation of Gene_expression of Arrb2 2 0.40 0.43 4.2
188 INT11277 Localization of Fos 22 0.78 6.58 4.19
189 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
190 INT67936 Transcription of JUN 18 0.52 9.52 4.13
191 INT64163 Negative_regulation of Gene_expression of Jun 13 0.58 3.86 4.03
192 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
193 INT156137 Gene_expression of Col1a2 28 0.73 13.3 3.99
194 INT10808 Negative_regulation of Negative_regulation of Fos 3 0.57 1.08 3.92
195 INT6661 Positive_regulation of Positive_regulation of Jun 31 0.50 7.12 3.89
196 INT60924 Regulation of Regulation of Fos 6 0.44 1.04 3.89
197 INT110180 Phosphorylation of JUN 23 0.80 11.21 3.83
198 INT85679 Binding of Arrb2 4 0.39 0.79 3.82
199 INT64817 Positive_regulation of Binding of Jun 16 0.69 6.78 3.81
200 INT84232 Negative_regulation of Transcription of Fos 9 0.58 1.84 3.78
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