GO:0007215

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Name glutamate receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0007215
Unique Molecular Interactions 34
Total Molecular Interactions 46
Total Single Events 303
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for glutamate receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for glutamate receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
2 INT40827 Sstr1 Negative_regulation of Localization of Gh1 1 0.13 0 1.58
3 INT19012 Ghsr Negative_regulation of Localization of Sstr1 1 0.10 0 1.44
4 INT112097 Sstr1 Positive_regulation of Adarb1 1 0.02 0.15 1.29
5 INT95791 Binding of SSTR1 and GRHL3 1 0.38 0.57 0.99
6 INT5107 Gal Positive_regulation of Localization of Sstr1 1 0.09 0 0.98
7 INT5104 Gal Positive_regulation of Sstr1 1 0.06 0 0.96
8 INT40826 Pomc Negative_regulation of Binding of Sstr1 1 0.05 0 0.74
9 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
10 INT8980 Gal Regulation of PLCB1 1 0.18 0.13 0.68
11 INT322809 Binding of GRIA3 and RS1 1 0.01 0.43 0.51
12 INT169083 Binding of GRIA3 and MOCOS 2 0.07 0.51 0.5
13 INT303655 Positive_regulation of Binding of IGF1 and SSTR1 1 0.16 2.19 0.41
14 INT124405 Binding of SST and SSTR1 1 0.01 0.5 0.41
15 INT303650 Binding of IGF1 and SSTR1 1 0.12 2.17 0.4
16 INT60817 Binding of Sstr1 and Bcl2l11 1 0.06 0 0.37
17 INT173356 Gnaq Positive_regulation of CDK20 1 0.06 0 0.37
18 INT5109 Gal Regulation of Localization of Sstr1 1 0.06 0 0.25
19 INT157957 Ppyr1 Negative_regulation of Phosphorylation of PLCB1 1 0.00 0.24 0.24
20 INT118857 PLCB1 Regulation of Phosphorylation of SRC 1 0.01 0.15 0.24
21 INT173358 Gnaq Positive_regulation of SMPD1 1 0.01 0.13 0.23
22 INT173357 Gnaq Positive_regulation of PRKCA 1 0.01 0 0.22
23 INT72019 Binding of Gnaq and Ptprg 1 0.01 0 0.21
24 INT40838 Sstr1 Negative_regulation of Positive_regulation of Vip 1 0.10 0 0.19
25 INT59808 Binding of AGT and PLCB1 1 0.02 0 0.13
26 INT59809 AGT Positive_regulation of PLCB1 1 0.03 0 0.13
27 INT59807 ADRA1D Positive_regulation of PLCB1 1 0.33 0 0.13
28 INT243468 Binding of SSTR1 and SSTR5 1 0.05 0.99 0.1
29 INT214752 EDNRA Positive_regulation of PLCB1 1 0.02 0 0.08
30 INT115933 U Regulation of PLCB1 1 0.00 0.3 0.08
31 INT227593 Gnaq Negative_regulation of GLUL 1 0.01 0 0.06
32 INT282504 Binding of Grik2 and Grik3 1 0.27 0.61 0
33 INT282507 Binding of Grik3 and ocd 1 0.25 0.61 0
34 INT313271 Binding of GRIN1 and GRIN2B 1 0.24 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for glutamate receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in glutamate receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5097 Localization of Sstr1 30 0.64 0.38 27.92
2 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32
3 INT18194 Positive_regulation of Localization of Sstr1 5 0.40 0 8.41
4 INT5094 Negative_regulation of Localization of Sstr1 8 0.36 0 5.98
5 INT40719 Binding of Sstr1 7 0.25 0.1 5.49
6 INT72000 Gene_expression of Gnaq 17 0.75 3.12 5.48
7 INT18195 Regulation of Localization of Sstr1 5 0.33 0 5.24
8 INT18193 Positive_regulation of Sstr1 6 0.31 1.82 4.8
9 INT24805 Gene_expression of Sstr1 4 0.37 1 4.06
10 INT169088 Gene_expression of GRIA3 7 0.76 1.32 2.67
11 INT50320 Transcription of Sstr1 3 0.43 0.53 2.58
12 INT19006 Negative_regulation of Sstr1 5 0.28 0.1 2.55
13 INT101055 Regulation of GRIN2B 4 0.61 1.39 2.5
14 INT13733 Localization of SSTR1 8 0.65 3.11 2.49
15 INT59818 Negative_regulation of PLCB1 7 0.57 2.24 2.28
16 INT95792 Regulation of SSTR1 5 0.57 2.98 2.27
17 INT18196 Regulation of Sstr1 3 0.34 0 2.26
18 INT112880 Positive_regulation of Gnaq 17 0.49 1.97 1.95
19 INT130440 Phosphorylation of GRIN2B 2 0.79 2.93 1.79
20 INT322821 Binding of GRIA3 1 0.47 2.06 1.67
21 INT110189 Regulation of Gnaq 3 0.02 0.26 1.63
22 INT71999 Negative_regulation of Gene_expression of Gnaq 3 0.41 0.08 1.56
23 INT107379 Localization of GRIN2B 2 0.73 0.86 1.48
24 INT13734 Regulation of Localization of SSTR1 1 0.23 0 1.43
25 INT124407 Gene_expression of SSTR1 4 0.55 5.55 1.41
26 INT59815 Positive_regulation of PLCB1 9 0.67 1.12 1.22
27 INT110188 Regulation of Gene_expression of Gnaq 2 0.25 0.85 1.22
28 INT95347 Negative_regulation of GRIN2B 1 0.57 0 1.19
29 INT322822 Regulation of GRIA3 4 0.61 1.19 1.11
30 INT72002 Negative_regulation of Gnaq 7 0.35 0.2 1.02
31 INT101056 Positive_regulation of GRIN2B 1 0.23 0.32 0.9
32 INT110187 Regulation of Regulation of Gnaq 1 0.00 0.07 0.82
33 INT141915 Positive_regulation of Gene_expression of Gnaq 3 0.19 1.31 0.76
34 INT114524 Binding of GRIN2B 3 0.36 0.44 0.74
35 INT322816 Transcription of GRIA3 2 0.71 0.75 0.7
36 INT322819 Regulation of Binding of GRIA3 1 0.61 1.07 0.68
37 INT59817 Gene_expression of PLCB1 4 0.75 0.73 0.65
38 INT243477 Binding of SSTR1 3 0.26 3.49 0.65
39 INT139895 Positive_regulation of Gene_expression of GRIN2B 2 0.49 0.9 0.65
40 INT230974 Positive_regulation of Gene_expression of GRIA3 2 0.49 0 0.57
41 INT86444 Positive_regulation of Gene_expression of Sstr1 1 0.25 0.15 0.57
42 INT112881 Positive_regulation of Positive_regulation of Gnaq 2 0.49 0.86 0.54
43 INT201278 Gene_expression of Grik3 1 0.41 0.55 0.52
44 INT13731 Negative_regulation of Localization of SSTR1 1 0.22 0 0.5
45 INT141919 Positive_regulation of Transcription of Gnaq 1 0.21 1.05 0.49
46 INT141912 Negative_regulation of Transcription of Gnaq 1 0.18 1.07 0.49
47 INT141917 Transcription of Gnaq 1 0.29 1.05 0.49
48 INT13736 Positive_regulation of Localization of SSTR1 1 0.19 0 0.49
49 INT95793 Positive_regulation of SSTR1 1 0.46 0.45 0.48
50 INT163895 Positive_regulation of Phosphorylation of GRIN2B 1 0.09 0.99 0.48
51 INT157955 Phosphorylation of PLCB1 1 0.01 0.46 0.46
52 INT124406 Positive_regulation of Gene_expression of SSTR1 1 0.01 0.6 0.44
53 INT352667 Positive_regulation of Transcription of GRIA3 1 0.08 0.39 0.42
54 INT352661 Positive_regulation of GRIA3 1 0.12 0.33 0.41
55 INT74604 Negative_regulation of Gene_expression of PLCB1 1 0.41 0.25 0.35
56 INT284758 Regulation of Grik3 1 0.17 0.07 0.33
57 INT169090 Regulation of Gene_expression of GRIA3 2 0.61 0.46 0.32
58 INT59816 Positive_regulation of Gene_expression of PLCB1 2 0.49 0.22 0.31
59 INT322820 Localization of GRIA3 1 0.74 0.31 0.31
60 INT235857 Binding of PLCB1 1 0.36 0.35 0.29
61 INT163897 Negative_regulation of Phosphorylation of GRIN2B 1 0.08 0.39 0.28
62 INT149315 Binding of Gnaq 2 0.04 0 0.26
63 INT157956 Regulation of Phosphorylation of PLCB1 1 0.00 0.22 0.22
64 INT322824 Regulation of Regulation of GRIA3 1 0.44 0.42 0.2
65 INT74602 Negative_regulation of Positive_regulation of PLCB1 1 0.41 0.25 0.19
66 INT303678 Regulation of Gene_expression of SSTR1 1 0.19 0.84 0.18
67 INT272710 Phosphorylation of Gnaq 1 0.09 0.12 0.12
68 INT59820 Regulation of Gene_expression of PLCB1 1 0.44 0 0.09
69 INT115930 Regulation of PLCB1 1 0.02 0.29 0.08
70 INT74606 Regulation of Negative_regulation of PLCB1 1 0.44 0.19 0.07
71 INT227570 Localization of Gnaq 1 0.07 0 0.04
72 INT227569 Negative_regulation of Positive_regulation of Gnaq 1 0.04 0.08 0.04
73 INT59814 Positive_regulation of Negative_regulation of PLCB1 1 0.45 0 0.04
74 INT356476 Transcription of SSTR1 1 0.20 0 0
75 INT282480 Binding of Grik3 1 0.39 0.61 0
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