GO:0007216

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Name G-protein coupled glutamate receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0007216
Unique Molecular Interactions 41
Total Molecular Interactions 55
Total Single Events 670
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for G-protein coupled glutamate receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for G-protein coupled glutamate receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT152949 Homer1 Regulation of Sgk1 1 0.28 0.18 0.76
2 INT152946 Homer1 Regulation of Cap1 1 0.32 0.18 0.76
3 INT152948 Homer1 Regulation of Gpr88 1 0.36 0.18 0.75
4 INT232617 Grid2ip Regulation of Cysltr1 1 0.03 0.58 0.68
5 INT164971 Binding of Rgs7 and Gnai2 1 0.01 0 0.54
6 INT164970 Binding of Rgs8 and Gnai2 1 0.01 0 0.53
7 INT232618 Gene_expression of Grid2ip Regulation of Localization of Gria1 1 0.28 0.86 0.52
8 INT81064 Negative_regulation of Nts Negative_regulation of Gene_expression of Homer1 1 0.01 0 0.48
9 INT232619 Binding of Gria1 and Grid2ip 1 0.23 0.51 0.48
10 INT72016 Positive_regulation of Binding of Gnai2 and Ptprg 1 0.02 0 0.44
11 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42
12 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42
13 INT72018 Binding of Gnai2 and Ptprg 1 0.01 0 0.41
14 INT141438 Gnai2 Positive_regulation of Localization of ADCY1 1 0.01 0.43 0.29
15 INT150582 Creb1 Positive_regulation of Gene_expression of Homer1 1 0.00 0 0.22
16 INT72015 Binding of Adora2a and Gnai2 1 0.01 0 0.21
17 INT174679 Homer1 Regulation of Luc7l3 1 0.02 0.67 0.21
18 INT58179 Gtf3a Positive_regulation of Gene_expression of Homer1 1 0.07 0.1 0.16
19 INT265982 Homer1 Regulation of Grm5 1 0.04 0.38 0.12
20 INT101880 Oxt Positive_regulation of Gene_expression of Homer1 1 0.23 0.14 0.1
21 INT265981 Homer1 Regulation of Localization of Grm5 1 0.04 0.06 0.09
22 INT265983 Homer1 Regulation of Ryr1 1 0.37 0.15 0.07
23 INT132849 Homer1 Regulation of Srf 1 0.01 0.15 0
24 INT282504 Binding of Grik2 and Grik3 1 0.27 0.61 0
25 INT282507 Binding of Grik3 and ocd 1 0.25 0.61 0
26 INT287077 Chrm2 Positive_regulation of Homer1 1 0.05 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for G-protein coupled glutamate receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in G-protein coupled glutamate receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7898 Gene_expression of Homer1 123 0.78 31.52 53.67
2 INT7899 Positive_regulation of Gene_expression of Homer1 41 0.70 7.29 25.98
3 INT47818 Positive_regulation of Homer1 48 0.70 11.11 24.05
4 INT60995 Negative_regulation of Positive_regulation of Homer1 9 0.38 1.63 9.63
5 INT15242 Regulation of Gene_expression of Homer1 14 0.62 4.33 9.28
6 INT53974 Regulation of Homer1 14 0.39 4.71 4.9
7 INT9798 Negative_regulation of Gene_expression of Homer1 10 0.41 2.04 3.77
8 INT60714 Regulation of Positive_regulation of Homer1 3 0.04 0.64 3.46
9 INT58173 Negative_regulation of Homer1 5 0.43 1 2.79
10 INT82278 Positive_regulation of Positive_regulation of Homer1 5 0.13 2.32 2.73
11 INT72013 Negative_regulation of Gnai2 5 0.35 0.09 2.44
12 INT61845 Transcription of Homer1 9 0.72 2.28 1.85
13 INT232607 Gene_expression of Grid2ip 1 0.65 2.35 1.85
14 INT63520 Localization of Homer1 4 0.75 0.38 1.63
15 INT72008 Gene_expression of Gnai2 4 0.38 0.42 1.49
16 INT232604 Localization of Grid2ip 1 0.72 1.33 1.43
17 INT82279 Regulation of Negative_regulation of Homer1 1 0.02 0 1.36
18 INT119214 Transcription of Gnai2 1 0.44 0.06 0.96
19 INT9797 Binding of Homer1 2 0.48 1.14 0.9
20 INT119213 Positive_regulation of Gnai2 1 0.42 0.06 0.88
21 INT232611 Binding of Grid2ip 1 0.36 0.46 0.61
22 INT76505 Positive_regulation of Transcription of Homer1 3 0.21 0.48 0.59
23 INT84854 Regulation of Transcription of Homer1 1 0.00 0.15 0.57
24 INT92523 Phosphorylation of Homer1 3 0.63 0.15 0.52
25 INT201278 Gene_expression of Grik3 1 0.41 0.55 0.52
26 INT232605 Negative_regulation of Gene_expression of Grid2ip 1 0.41 0.85 0.49
27 INT232609 Positive_regulation of Grid2ip 1 0.48 0.71 0.46
28 INT72014 Negative_regulation of Gene_expression of Gnai2 1 0.24 0 0.4
29 INT284758 Regulation of Grik3 1 0.17 0.07 0.33
30 INT232606 Negative_regulation of Grid2ip 1 0.36 0 0.03
31 INT282480 Binding of Grik3 1 0.39 0.61 0
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