GO:0007217

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Name tachykinin receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0007217
Unique Molecular Interactions 281
Total Molecular Interactions 363
Total Single Events 4451
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tachykinin receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for tachykinin receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
2 INT71069 Oprl1 Regulation of Gene_expression of Tac4 1 0.03 0.13 3.64
3 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
4 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
5 INT314141 Binding of Tacr3 and SFTPA1 1 0.00 3.02 2.48
6 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25
7 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
8 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
9 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
10 INT14576 Tac4 Regulation of Penk 1 0.07 0 1.77
11 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
12 INT169441 TAC1 Positive_regulation of Tac1 1 0.01 1.7 1.64
13 INT147258 Binding of Tac1 and Penk 1 0.35 0 1.64
14 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
15 INT73016 PDYN Regulation of TAC1 1 0.29 0.34 1.54
16 INT274943 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Tac2 1 0.04 0.49 1.53
17 INT116094 Binding of TACR1 and TFF2 1 0.06 0 1.47
18 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
19 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
20 INT202910 Uchl1 Positive_regulation of Gene_expression of Tacr1 1 0.05 1.65 1.42
21 INT329451 Binding of Oprd1 and Tacr1 1 0.05 0.23 1.41
22 INT71543 IFNA1 Negative_regulation of Positive_regulation of TAC1 1 0.20 0.19 1.4
23 INT329452 Binding of Tac1 and Oprd1 1 0.01 0.23 1.4
24 INT167528 Ppt1 Negative_regulation of Gene_expression of Tac4 1 0.06 0.49 1.39
25 INT51160 Binding of TAC1 and Tacr1 2 0.28 0.55 1.38
26 INT15277 Binding of Tac1 and Gal 1 0.39 0.19 1.35
27 INT185330 Binding of Hrh1 and Tac1 1 0.00 0.1 1.34
28 INT49231 TAC1 Negative_regulation of Penk 1 0.00 0 1.3
29 INT95457 Nka1 Positive_regulation of Tacr1 1 0.63 0.29 1.3
30 INT147653 TACR1 Positive_regulation of TRPV1 1 0.02 0.72 1.29
31 INT138213 Mzb1 Regulation of Localization of Tac1 1 0.01 0.41 1.29
32 INT138214 Mzb1 Regulation of Tac1 1 0.01 0.41 1.28
33 INT70226 Binding of TAC1 and B3GAT1 4 0.24 4.5 1.26
34 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
35 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
36 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
37 INT122370 Positive_regulation of Tacr1 Positive_regulation of Ngf 1 0.30 0.17 1.18
38 INT48809 Pax3 Negative_regulation of Binding of Tac1 1 0.22 0 1.16
39 INT339331 Binding of TACR1 and SFTPA1 1 0.04 0.12 1.14
40 INT122369 Tacr1 Positive_regulation of Ngf 1 0.30 0.16 1.14
41 INT86263 Binding of Tacr3 and Tac2 1 0.16 0.52 1.13
42 INT73679 Nkx1-1 Positive_regulation of Tacr3 1 0.22 0.26 1.12
43 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11
44 INT113540 Binding of OPRM1 and Tac1 1 0.04 0.1 1.1
45 INT314136 Binding of TAC1 and SFTPA1 2 0.03 0.78 1.06
46 INT94205 TACR1 Regulation of Gene_expression of SP5 1 0.04 0.72 1.06
47 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
48 INT339333 Binding of TACR1 and TAC4 1 0.48 0.32 1.05
49 INT63181 Oprl1 Regulation of Localization of Tacr1 1 0.06 0.09 1.04
50 INT8416 LIF Regulation of TAC1 1 0.13 0.36 1.04
51 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
52 INT75247 Abat Regulation of Gene_expression of Tacr1 1 0.23 0.41 1.03
53 INT84959 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Tac1 1 0.48 0.59 1.02
54 INT107951 Pax3 Positive_regulation of Tac1 1 0.11 1.21 0.95
55 INT314142 Binding of TAC1 and Tacr3 1 0.06 0.73 0.94
56 INT24938 TAC1 Regulation of Calca 1 0.22 0.35 0.94
57 INT24939 TAC3 Regulation of Calca 1 0.01 0.35 0.94
58 INT70803 Ngf Regulation of Tac4 1 0.06 0.39 0.93
59 INT24941 TAC3 Regulation of Nka1 1 0.00 0.34 0.92
60 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92
61 INT86349 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Fos 1 0.42 0.8 0.92
62 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
63 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89
64 INT252881 Crcp Positive_regulation of Gene_expression of Tacr1 1 0.00 0.28 0.88
65 INT24940 TAC1 Regulation of Nka1 1 0.10 0.34 0.87
66 INT121745 Tacr1 Negative_regulation of Positive_regulation of Ephb1 1 0.04 0 0.87
67 INT146495 Snta1 Positive_regulation of Adrbk1 1 0.14 0.68 0.85
68 INT113237 Il10 Negative_regulation of Gene_expression of Tacr1 1 0.35 0.81 0.84
69 INT113240 Il12a Regulation of Transcription of Tacr1 1 0.21 0.79 0.82
70 INT114844 Lgals1 Positive_regulation of TACR1 1 0.16 0.95 0.82
71 INT84103 TACR1 Regulation of Nka1 1 0.00 0 0.81
72 INT113239 Il10 Regulation of Transcription of Tacr1 1 0.45 0.79 0.81
73 INT208946 Positive_regulation of Tacr1 Positive_regulation of Gene_expression of S100a8 1 0.02 1.11 0.8
74 INT113238 Il12a Positive_regulation of Transcription of Tacr1 1 0.38 0.78 0.79
75 INT132977 Tac1 Positive_regulation of Mapk1 1 0.06 0.17 0.79
76 INT92293 Tacr1 Regulation of Tac2 1 0.17 0.07 0.79
77 INT79339 Phax Regulation of Gene_expression of Tacr1 1 0.07 0 0.78
78 INT87513 Binding of Tac2 and Abat 1 0.09 0.26 0.78
79 INT213978 Binding of TAC1 and Tac1 1 0.02 0.36 0.78
80 INT148061 Binding of Tacr1 and B4galt4 1 0.01 0.06 0.77
81 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
82 INT95458 Nka1 Positive_regulation of Positive_regulation of Tacr1 1 0.52 0.16 0.77
83 INT148062 Binding of Tacr1 and St3gal3 1 0.01 0.06 0.77
84 INT124384 ADRBK1 Negative_regulation of MC1R 1 0.40 0.42 0.77
85 INT94816 Prkcg Positive_regulation of TACR1 1 0.06 0.1 0.76
86 INT15344 Oprd1 Regulation of Localization of Tacr3 1 0.00 0 0.76
87 INT49044 Tac2 Regulation of Gene_expression of Tacr3 1 0.17 0.32 0.76
88 INT202909 Binding of Tacr1 and Fig4 1 0.03 0.33 0.74
89 INT4917 Binding of Pcolce and Tac2 1 0.03 0 0.74
90 INT41919 Binding of Tacr1 and Trh 1 0.06 0 0.74
91 INT4915 Binding of Tac2 and Gipc1 1 0.01 0 0.74
92 INT8367 Tacr1 Positive_regulation of Localization of Prss12 1 0.05 0 0.72
93 INT73822 TAC1 Positive_regulation of Localization of IL1B 1 0.04 0.56 0.71
94 INT294906 Binding of Pax3 and Tac4 1 0.01 1.15 0.71
95 INT207411 Sst Negative_regulation of Gene_expression of Tacr1 1 0.05 0.76 0.69
96 INT140235 ADRBK1 Positive_regulation of Binding of MC1R 1 0.46 0.31 0.68
97 INT140237 Gene_expression of ADRBK1 Positive_regulation of Gene_expression of MC1R 1 0.46 0.31 0.68
98 INT79937 TAC1 Positive_regulation of Gene_expression of VCAM1 1 0.20 0.15 0.68
99 INT109718 Tac1 Negative_regulation of Mpo 1 0.25 0.81 0.67
100 INT147257 Tac1 Regulation of Penk 1 0.19 0 0.67
101 INT207410 Ptger2 Regulation of Gene_expression of Tacr1 1 0.02 0.69 0.65
102 INT189020 Tacr1 Positive_regulation of Pla2g1b 1 0.14 0.13 0.65
103 INT63655 Binding of NPY and TAC1 1 0.39 0.17 0.64
104 INT124904 Binding of Tacr1 and Adarb1 2 0.01 0.5 0.63
105 INT93690 Bdnf Regulation of Localization of Tacr1 1 0.10 0.28 0.61
106 INT167859 Tac1 Regulation of Gene_expression of Tacr1 1 0.09 0 0.6
107 INT81606 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TACR1 1 0.29 0 0.6
108 INT339332 TAC4 Positive_regulation of Gene_expression of SFTPA1 1 0.04 0.05 0.59
109 INT339347 Nka1 Positive_regulation of Gene_expression of TAC4 1 0.05 0 0.58
110 INT121288 Binding of TAC1 and Cd79a 1 0.12 0.32 0.58
111 INT166300 Adrbk1 Positive_regulation of Negative_regulation of Gpbar1 1 0.39 0.63 0.58
112 INT339349 TAC4 Positive_regulation of Gene_expression of Nka1 1 0.05 0 0.58
113 INT81605 PRKCA Positive_regulation of Phosphorylation of TACR1 1 0.43 0 0.57
114 INT339337 Binding of SARDH and TACR1 1 0.01 0.06 0.57
115 INT339335 Binding of MET and TACR1 1 0.06 0.06 0.57
116 INT76248 Tac1 Positive_regulation of Gene_expression of Fos 1 0.34 0.34 0.56
117 INT14387 GAL Regulation of TAC1 1 0.10 0 0.56
118 INT69898 Binding of Olfr19 and Tacr1 1 0.00 0.1 0.55
119 INT282821 TACR1 Regulation of P2RX7 1 0.01 2.06 0.54
120 INT339334 TAC4 Negative_regulation of B3GAT1 1 0.17 0.15 0.53
121 INT49225 Mdk Regulation of Tac1 1 0.00 0 0.53
122 INT106394 MAPK3 Positive_regulation of ADRBK1 1 0.48 0.06 0.53
123 INT48646 Sst Regulation of Tacr1 1 0.03 0.09 0.52
124 INT106392 ADRBK1 Regulation of Negative_regulation of OPRL1 1 0.27 0.06 0.52
125 INT165042 Drd2 Regulation of Tac1 1 0.22 0 0.52
126 INT8438 Cntf Regulation of TAC1 1 0.20 0.18 0.52
127 INT126341 Tac1 Regulation of Gene_expression of Tnfrsf10b 1 0.06 0.71 0.52
128 INT14410 Tac1 Negative_regulation of Calca 1 0.26 0.33 0.52
129 INT151222 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Adrbk1 1 0.00 0.13 0.51
130 INT151223 Negative_regulation of SIGMAR1 Negative_regulation of Adrbk1 1 0.00 0.13 0.51
131 INT98684 Tac2 Positive_regulation of Gene_expression of Fos 1 0.12 0.16 0.51
132 INT15273 Calca Regulation of Tacr1 1 0.22 0 0.5
133 INT157003 Gal Regulation of Localization of Tacr1 1 0.01 0.1 0.49
134 INT126336 Negative_regulation of Binding of Pax3 and Tac1 1 0.01 0.66 0.49
135 INT81331 ADRBK1 Regulation of OPRK1 1 0.03 0.09 0.48
136 INT97487 ADCYAP1 Positive_regulation of Tac1 1 0.02 0 0.48
137 INT88696 Tac1 Regulation of Regulation of Mme 1 0.00 0.39 0.48
138 INT58578 Binding of RPA1 and TACR1 1 0.01 0 0.48
139 INT66438 Tac2 Regulation of Binding of TAC1 1 0.01 0.12 0.47
140 INT339350 Binding of TAC4 and Nka1 1 0.03 0.06 0.46
141 INT127398 Negative_regulation of Mdk Negative_regulation of Gene_expression of Tacr1 1 0.01 0.71 0.45
142 INT67733 Binding of Tac1 and SLAMF6 1 0.00 0.17 0.45
143 INT127395 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Tacr1 1 0.07 0.71 0.45
144 INT101981 D2Ertd127e Positive_regulation of TAC1 1 0.00 0 0.44
145 INT51025 Klra3 Positive_regulation of Gene_expression of Tac1 1 0.11 0 0.42
146 INT113537 Binding of OPRM1 and TACR1 1 0.01 0.1 0.42
147 INT15356 Abat Regulation of Tacr1 1 0.02 0 0.42
148 INT51026 Klra3 Positive_regulation of Gene_expression of Tacr3 1 0.05 0 0.42
149 INT151633 Binding of Npy and Tacr1 1 0.16 0.39 0.4
150 INT114597 Positive_regulation of Trib3 Regulation of Gene_expression of Tac4 1 0.01 0.09 0.4
151 INT41612 Tac1 Regulation of Localization of Sst 1 0.02 0 0.39
152 INT282820 Binding of TACR1 and NCOR2 1 0.00 0.88 0.39
153 INT13077 Tac2 Positive_regulation of NKX2-1 1 0.00 0 0.39
154 INT163918 Ntp Negative_regulation of Gene_expression of Tacr1 1 0.04 0.74 0.38
155 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
156 INT63706 TACR1 Negative_regulation of B3GAT1 1 0.02 0.12 0.37
157 INT63707 TACR1 Negative_regulation of TAC1 1 0.03 0.12 0.37
158 INT337114 Tg(CAG-EGFP)D4Nagy Positive_regulation of Gene_expression of TAC1 1 0.04 0.07 0.36
159 INT265145 Calm2 Negative_regulation of Phosphorylation of Adrbk1 1 0.05 0.07 0.35
160 INT46147 Dpa Negative_regulation of TAC1 1 0.01 0.09 0.34
161 INT46145 HLA-DQA1 Negative_regulation of TAC1 1 0.04 0.09 0.34
162 INT101968 TAC1 Regulation of PENK 1 0.00 0 0.33
163 INT353128 Negative_regulation of Binding of TAC1 and B3GAT1 1 0.29 1.95 0.33
164 INT207408 Il6 Positive_regulation of Gene_expression of Tacr1 1 0.08 0.56 0.33
165 INT101978 Regulation of Tac1 Regulation of PENK 1 0.01 0 0.33
166 INT101979 TAC1 Regulation of Tac1 1 0.01 0 0.33
167 INT101980 Tac1 Regulation of PENK 1 0.01 0 0.33
168 INT106871 Grip2 Regulation of Tacr3 1 0.00 0 0.32
169 INT222441 Tlr4 Positive_regulation of Gene_expression of Tac1 1 0.00 0.39 0.32
170 INT207409 Ptger2 Positive_regulation of Gene_expression of Tacr1 1 0.04 0.56 0.32
171 INT106397 Positive_regulation of OPRL1 Positive_regulation of ADRBK1 1 0.46 0.09 0.31
172 INT102976 Binding of ADRBK1 and Rbm39 1 0.00 0 0.31
173 INT265138 Adrbk1 Positive_regulation of Localization of Chrm1 1 0.07 0 0.31
174 INT116680 Binding of ADRBK1 and Oxtr 1 0.18 0.14 0.3
175 INT102955 OPRK1 Positive_regulation of Localization of ADRBK1 1 0.13 0 0.3
176 INT83569 Grk5 Regulation of Oprk1 1 0.02 0 0.29
177 INT208940 Pax3 Positive_regulation of Tacr1 1 0.07 0.55 0.29
178 INT75108 Binding of Tac2 and Tacr1 1 0.18 0.1 0.29
179 INT145283 Msr1 Negative_regulation of Tac4 1 0.00 0 0.29
180 INT106893 Ptpn2 Positive_regulation of Tac1 1 0.02 2.02 0.29
181 INT208941 Positive_regulation of Pax3 Positive_regulation of Tacr1 1 0.05 0.55 0.29
182 INT339338 Binding of TAC4 and SFTPA1 1 0.03 0 0.28
183 INT124340 Tacr1 Positive_regulation of Tac2 1 0.48 0 0.27
184 INT14412 Positive_regulation of Tac1 Negative_regulation of Calca 1 0.28 0.16 0.26
185 INT294912 Binding of Pax3 and Tacr3 1 0.01 1.54 0.25
186 INT208936 Tac1 Positive_regulation of Tacr1 1 0.13 0.39 0.25
187 INT118418 Gata1 Positive_regulation of Transcription of Tac2 1 0.61 0.77 0.25
188 INT278581 Tacr2 Positive_regulation of Tacr1 1 0.55 0 0.24
189 INT118419 Binding of Gata1 and Tac2 1 0.31 0.7 0.24
190 INT70659 Binding of Tacr3 and Hrasls 1 0.00 0 0.24
191 INT278582 Atp6v1e1 Positive_regulation of Positive_regulation of Tac1 1 0.15 0.13 0.24
192 INT278578 Tacr3 Positive_regulation of Tacr1 1 0.55 0 0.24
193 INT278570 Nka1 Positive_regulation of Tacr1 1 0.06 0 0.24
194 INT66437 Tac2 Regulation of TAC1 1 0.01 0.06 0.23
195 INT65525 Tacr1 Regulation of Regulation of Spn 1 0.15 0.36 0.22
196 INT224087 Adrbk1 Negative_regulation of Adora2a 1 0.10 0.13 0.22
197 INT180600 MAOB Positive_regulation of TAC1 1 0.00 0.13 0.22
198 INT48509 GRP Positive_regulation of Localization of Tac1 1 0.00 0 0.22
199 INT107031 Regulation of Binding of Tacr1 and Oprm1 1 0.29 0.5 0.21
200 INT55828 Bdnf Negative_regulation of Negative_regulation of Tac4 1 0.09 0 0.21

Single Events

The table below shows the top 100 pain related interactions that have been reported for tachykinin receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in tachykinin receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92
2 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46
3 INT4936 Localization of Tacr1 125 0.80 35.7 107.7
4 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66
5 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52
6 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26
7 INT5017 Negative_regulation of Tacr1 76 0.58 17 57.07
8 INT37219 Gene_expression of TACR1 56 0.78 32.4 54.16
9 INT8690 Localization of Tac1 71 0.80 22.98 50.75
10 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67
11 INT8713 Regulation of Tac1 56 0.60 25.29 45.94
12 INT4776 Localization of TAC1 82 0.78 16.89 45.21
13 INT14853 Negative_regulation of Tac1 80 0.59 30.87 45.06
14 INT4850 Binding of Tac1 57 0.47 14.25 42.17
15 INT4887 Gene_expression of Tac4 70 0.77 11.66 40.97
16 INT4925 Binding of Tacr1 57 0.48 17.39 38.38
17 INT65125 Gene_expression of Tacr1 81 0.77 23.9 38.35
18 INT8837 Positive_regulation of TAC1 59 0.67 21.94 35.97
19 INT4892 Positive_regulation of Gene_expression of Tacr1 56 0.69 25.64 34.69
20 INT4727 Regulation of TAC1 60 0.47 6.74 32.83
21 INT22239 Negative_regulation of TAC1 52 0.57 12.96 31.41
22 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19
23 INT11773 Gene_expression of Tac1 56 0.77 10 25.72
24 INT8779 Binding of TAC1 50 0.47 11.19 25.57
25 INT11979 Transcription of Tac4 42 0.52 4.48 20.95
26 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
27 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
28 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
29 INT41494 Negative_regulation of Gene_expression of Tacr1 25 0.58 11.73 19.91
30 INT12360 Regulation of Tac1 31 0.61 5.9 18
31 INT11977 Positive_regulation of Tac4 26 0.69 3.91 17.15
32 INT15202 Regulation of Tacr1 26 0.60 9.65 16.48
33 INT11980 Positive_regulation of Tac1 27 0.69 6.17 14.5
34 INT51158 Positive_regulation of Tacr1 33 0.70 15.22 13.91
35 INT8756 Gene_expression of Tac2 26 0.78 2.64 13.39
36 INT24956 Gene_expression of Tacr3 22 0.74 7.21 13.37
37 INT49041 Transcription of Tacr1 25 0.72 12.52 12.8
38 INT57580 Positive_regulation of TACR1 18 0.69 9.35 12.47
39 INT4784 Gene_expression of TAC4 25 0.71 9.84 11.54
40 INT4895 Positive_regulation of Gene_expression of Tac4 16 0.69 2.46 11.51
41 INT143098 Negative_regulation of Gene_expression of Adrbk1 9 0.58 8.51 11.37
42 INT48691 Negative_regulation of Tacr1 20 0.59 4.96 11.25
43 INT4723 Transcription of Tac1 26 0.71 8.33 11.18
44 INT8589 Positive_regulation of Positive_regulation of Tacr1 14 0.69 7.85 10.86
45 INT23519 Positive_regulation of Localization of Tacr1 12 0.41 3.84 10.82
46 INT54706 Regulation of Adrbk1 11 0.62 0.89 10.69
47 INT48806 Negative_regulation of Binding of Tac1 11 0.56 0.83 10.52
48 INT51168 Localization of TACR1 10 0.80 7.66 9.83
49 INT54707 Positive_regulation of Adrbk1 14 0.67 0.51 9.51
50 INT53547 Binding of TACR1 22 0.48 5.03 9.48
51 INT105839 Positive_regulation of Grk5 5 0.70 0.35 9.2
52 INT51837 Negative_regulation of TACR1 17 0.43 6.5 9.12
53 INT12358 Regulation of Gene_expression of Tac1 17 0.60 3.34 8.84
54 INT23331 Positive_regulation of Localization of Tac1 10 0.54 4.63 8.76
55 INT4984 Positive_regulation of Positive_regulation of Tac1 11 0.50 5.34 8.73
56 INT76814 Positive_regulation of Gene_expression of Tacr1 13 0.69 6.11 8.42
57 INT81610 Phosphorylation of TACR1 1 0.81 0.76 8.38
58 INT4940 Negative_regulation of Localization of Tacr1 8 0.37 4.29 8.25
59 INT22700 Positive_regulation of Gene_expression of Tac1 13 0.69 6.89 8.2
60 INT48877 Binding of Tacr1 16 0.43 5.26 8.04
61 INT81345 Gene_expression of ADRBK1 21 0.70 2.89 7.9
62 INT51206 Regulation of Gene_expression of Tac1 13 0.45 5.92 7.74
63 INT14548 Localization of Tac1 13 0.78 1.43 7.48
64 INT31361 Regulation of Gene_expression of Tac4 15 0.57 1.07 7.31
65 INT98856 Negative_regulation of Gene_expression of Adrbk1 5 0.56 0.43 7.29
66 INT50779 Positive_regulation of Gene_expression of Adrbk1 9 0.56 2.79 7.23
67 INT12359 Negative_regulation of Tac1 26 0.58 8.16 6.89
68 INT11975 Transcription of Tac1 24 0.71 4.06 6.72
69 INT8753 Positive_regulation of Tac2 10 0.60 1.8 6.69
70 INT24884 Negative_regulation of Positive_regulation of Tacr1 8 0.43 2.35 6.66
71 INT15674 Positive_regulation of Gene_expression of Tac1 17 0.68 4.97 6.56
72 INT11976 Positive_regulation of Transcription of Tac4 11 0.44 1.57 6.44
73 INT24536 Regulation of Localization of Tacr1 5 0.30 3.39 6.44
74 INT46812 Gene_expression of Tac2 12 0.75 1.34 6.17
75 INT14490 Positive_regulation of Tacr3 14 0.53 1.83 5.77
76 INT14388 Regulation of TACR1 12 0.45 3.1 5.58
77 INT129645 Negative_regulation of Gene_expression of TAC1 5 0.42 3.33 5.55
78 INT63395 Regulation of Regulation of Tacr1 6 0.45 2.26 5.39
79 INT66288 Positive_regulation of Transcription of Tacr1 10 0.70 5.06 5.37
80 INT4920 Localization of Tac2 11 0.80 0.71 5.29
81 INT8755 Regulation of Tac2 12 0.62 0.56 5.27
82 INT5303 Gene_expression of TAC3 19 0.75 5.25 5.2
83 INT81609 Positive_regulation of Phosphorylation of TACR1 1 0.60 0.33 4.91
84 INT14771 Regulation of Localization of Tac1 4 0.48 1.77 4.83
85 INT8838 Positive_regulation of Localization of TAC1 7 0.49 0.86 4.7
86 INT41816 Negative_regulation of Localization of Tac1 5 0.35 1.2 4.66
87 INT92446 Positive_regulation of Gene_expression of TACR1 4 0.35 2.68 4.5
88 INT50630 Negative_regulation of Tac4 14 0.58 0.34 4.45
89 INT8950 Gene_expression of Tacr3 12 0.76 0.97 4.07
90 INT100741 Positive_regulation of ADRBK1 10 0.64 1.01 3.95
91 INT5299 Regulation of Tacr3 11 0.34 1.51 3.93
92 INT117561 Positive_regulation of Transcription of Tac1 6 0.69 3.19 3.78
93 INT15343 Localization of Tacr3 7 0.76 2.11 3.69
94 INT14936 Negative_regulation of Binding of Tacr1 4 0.58 0.75 3.67
95 INT8952 Negative_regulation of Tacr3 7 0.42 0.36 3.62
96 INT53142 Negative_regulation of Gene_expression of Tac1 7 0.56 1.59 3.61
97 INT81115 Negative_regulation of Tac2 5 0.56 0.73 3.51
98 INT15114 Negative_regulation of Tac2 7 0.40 0.71 3.5
99 INT122438 Transcription of Grk5 1 0.72 0 3.46
100 INT83565 Gene_expression of Grk5 5 0.55 0.16 3.39
101 INT52493 Positive_regulation of Positive_regulation of Tac4 3 0.13 0.45 3.21
102 INT8599 Binding of Tacr3 6 0.21 0.19 3.2
103 INT8754 Transcription of Tac2 5 0.72 0.34 3.18
104 INT15276 Binding of Tac1 6 0.36 0.56 3.16
105 INT122441 Regulation of Grk5 1 0.62 0 3.13
106 INT54709 Positive_regulation of Gene_expression of Adrbk1 6 0.49 0.18 3.12
107 INT50636 Regulation of Tac4 9 0.53 0.33 3.1
108 INT105840 Regulation of Gene_expression of Adrbk1 2 0.44 0.16 3.09
109 INT73017 Regulation of Gene_expression of TAC1 5 0.54 0.44 3.08
110 INT51422 Negative_regulation of Gene_expression of Tac2 1 0.41 0.16 3.02
111 INT74674 Transcription of TAC1 7 0.67 1 3.01
112 INT71398 Regulation of Tacr3 5 0.53 1.15 2.91
113 INT102969 Positive_regulation of Gene_expression of ADRBK1 7 0.46 1.21 2.87
114 INT107950 Regulation of Gene_expression of Tacr1 6 0.61 1.13 2.84
115 INT99592 Regulation of Adrbk1 3 0.61 1.46 2.84
116 INT51307 Negative_regulation of Positive_regulation of TAC1 4 0.42 2 2.82
117 INT65126 Transcription of Tacr1 5 0.63 3.44 2.77
118 INT8590 Regulation of Positive_regulation of Tacr1 4 0.62 1.43 2.73
119 INT110503 Negative_regulation of ADRBK1 4 0.53 0.71 2.69
120 INT73837 Positive_regulation of Gene_expression of TAC1 6 0.67 3.49 2.68
121 INT105837 Regulation of Gene_expression of Grk5 1 0.44 0.16 2.68
122 INT21740 Localization of TAC3 7 0.73 1.46 2.6
123 INT94978 Negative_regulation of Adrbk1 6 0.38 0.13 2.47
124 INT122367 Positive_regulation of Positive_regulation of Tacr1 5 0.46 1.47 2.4
125 INT105838 Negative_regulation of Grk5 2 0.43 0.1 2.37
126 INT53069 Regulation of Transcription of Tac4 4 0.23 0.49 2.36
127 INT94814 Negative_regulation of Positive_regulation of TACR1 2 0.26 1.98 2.35
128 INT91046 Negative_regulation of Regulation of Tacr1 3 0.40 1.33 2.31
129 INT36927 Regulation of Transcription of Tac1 3 0.26 0.33 2.27
130 INT98898 Localization of Tacr1 6 0.72 2.47 2.25
131 INT49139 Positive_regulation of Positive_regulation of Tac1 4 0.68 1.74 2.24
132 INT86262 Negative_regulation of Tacr3 3 0.41 0.57 2.2
133 INT72842 Phosphorylation of Adrbk1 5 0.47 0.58 2.16
134 INT49183 Positive_regulation of Positive_regulation of TAC1 4 0.49 0.66 2.15
135 INT146491 Binding of Adrbk1 3 0.48 1.58 2.09
136 INT100498 Negative_regulation of Positive_regulation of Tac1 3 0.41 2.81 2.06
137 INT72277 Negative_regulation of TAC4 3 0.53 0.74 2.05
138 INT136471 Phosphorylation of Tacr1 4 0.46 1.03 1.99
139 INT61650 Protein_catabolism of Tac1 3 0.52 0.88 1.98
140 INT65866 Regulation of Tac2 4 0.44 0.28 1.95
141 INT24230 Localization of Tacr3 3 0.21 0 1.94
142 INT102970 Localization of ADRBK1 4 0.66 0.45 1.85
143 INT31360 Negative_regulation of Positive_regulation of Tac4 2 0.55 0 1.81
144 INT37220 Regulation of Gene_expression of TACR1 2 0.43 0.46 1.73
145 INT118405 Positive_regulation of Tac2 3 0.58 0.74 1.68
146 INT60027 Negative_regulation of Gene_expression of Tac4 4 0.58 0.26 1.67
147 INT73870 Positive_regulation of Regulation of Adrbk1 1 0.47 0.17 1.66
148 INT339341 Binding of TAC4 1 0.34 0.32 1.62
149 INT4912 Binding of Tac2 2 0.36 0.09 1.58
150 INT58598 Regulation of Gene_expression of Tacr3 1 0.37 0.98 1.54
151 INT34523 Positive_regulation of Gene_expression of Tac2 3 0.55 0.38 1.53
152 INT49043 Regulation of Gene_expression of Tac2 1 0.50 0.66 1.53
153 INT94965 Transcription of Adrbk1 2 0.22 0.13 1.52
154 INT8954 Negative_regulation of Positive_regulation of Tac2 2 0.47 0.44 1.52
155 INT49042 Positive_regulation of Gene_expression of Tacr3 2 0.42 0.7 1.5
156 INT149634 Regulation of TAC4 2 0.36 0.18 1.49
157 INT14856 Regulation of Negative_regulation of Tacr1 1 0.20 0.21 1.46
158 INT4918 Binding of Tac2 4 0.48 0.33 1.45
159 INT110747 Gene_expression of Tac4 3 0.74 0.42 1.44
160 INT80770 Positive_regulation of Binding of Tac1 2 0.12 0.45 1.37
161 INT58597 Positive_regulation of Transcription of Tacr3 1 0.28 0.67 1.37
162 INT100569 Positive_regulation of Binding of Tacr1 1 0.50 0.66 1.37
163 INT151216 Positive_regulation of Adrbk1 2 0.46 0.9 1.3
164 INT131984 Positive_regulation of Localization of Tacr3 1 0.01 0 1.28
165 INT50897 Negative_regulation of Transcription of Tac4 3 0.43 0 1.25
166 INT49204 Protein_catabolism of Tacr1 3 0.50 0.84 1.24
167 INT82003 Negative_regulation of Localization of Tac1 2 0.20 0.1 1.23
168 INT94967 Localization of Adrbk1 2 0.26 0.33 1.21
169 INT65124 Negative_regulation of Positive_regulation of Tacr1 3 0.53 0.9 1.18
170 INT112931 Negative_regulation of Localization of Adrbk1 1 0.37 0 1.13
171 INT105916 Negative_regulation of Gene_expression of TACR1 1 0.03 0.53 1.13
172 INT58599 Transcription of Tacr3 3 0.43 1.02 1.12
173 INT112932 Localization of Adrbk1 1 0.69 0 1.12
174 INT50174 Negative_regulation of Gene_expression of Tac1 3 0.40 0.32 1.11
175 INT106404 Positive_regulation of Positive_regulation of ADRBK1 2 0.41 0.31 1.08
176 INT82483 Negative_regulation of Positive_regulation of Tac1 3 0.47 0 1.06
177 INT78812 Transcription of TACR1 4 0.68 0.93 1.05
178 INT98849 Binding of Adrbk1 3 0.36 0.18 1.04
179 INT98855 Negative_regulation of Binding of Adrbk1 2 0.41 0.18 1.04
180 INT72274 Transcription of TAC4 2 0.63 0.4 1.04
181 INT8951 Negative_regulation of Gene_expression of Tacr3 2 0.42 0.14 1.01
182 INT8948 Regulation of Negative_regulation of Tacr3 1 0.15 0 1.01
183 INT146492 Positive_regulation of Negative_regulation of Adrbk1 1 0.50 0.74 1
184 INT219031 Positive_regulation of Regulation of Tacr1 1 0.26 0.65 0.95
185 INT122439 Positive_regulation of Transcription of Grk5 1 0.70 0 0.94
186 INT24851 Negative_regulation of Regulation of TAC1 1 0.02 0 0.93
187 INT111883 Negative_regulation of Transcription of Adrbk1 1 0.33 0 0.93
188 INT111887 Transcription of Adrbk1 1 0.56 0 0.92
189 INT60985 Regulation of Transcription of Tac1 4 0.27 1.75 0.88
190 INT63785 Positive_regulation of Tacr3 2 0.11 0.08 0.88
191 INT14935 Regulation of Binding of Tacr1 1 0.24 0 0.88
192 INT24957 Negative_regulation of Gene_expression of Tacr3 1 0.21 0.49 0.87
193 INT132587 Negative_regulation of Gene_expression of Tacr1 3 0.57 1.22 0.85
194 INT51195 Binding of TAC3 3 0.03 0.09 0.84
195 INT23842 Protein_catabolism of TAC1 2 0.96 0.57 0.84
196 INT60028 Localization of Tac4 2 0.33 0 0.83
197 INT69749 Binding of Tacr3 3 0.06 2.2 0.81
198 INT49181 Regulation of Positive_regulation of Tac1 1 0.12 0 0.81
199 INT72276 Negative_regulation of Gene_expression of TAC4 1 0.15 0.36 0.8
200 INT113536 Positive_regulation of Phosphorylation of Tac1 1 0.07 0.08 0.79
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