GO:0007260

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Name tyrosine phosphorylation of STAT protein
Categary Process
Go Slim No
Go Link GO:0007260
Unique Molecular Interactions 392
Total Molecular Interactions 554
Total Single Events 3404
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tyrosine phosphorylation of STAT protein. They are ordered first by their pain relevance and then by number of times they were reported for tyrosine phosphorylation of STAT protein. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
2 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
3 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
4 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
5 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
6 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
7 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
8 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
9 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
10 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
11 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
12 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
13 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
14 INT207149 Binding of F2r and Par2 1 0.17 1.64 0.92
15 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78
16 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77
17 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
18 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
19 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
20 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
21 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74
22 INT338057 Positive_regulation of F2r Positive_regulation of Localization of Calca 1 0.05 0.28 0.71
23 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
24 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
25 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
26 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
27 INT150338 Binding of F2 and F2R 1 0.11 0.4 0.67
28 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
29 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
30 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
31 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56
32 INT167907 Binding of F2r and ITS 1 0.01 0.7 0.55
33 INT113162 Lep Positive_regulation of Positive_regulation of Insrr 1 0.03 0 0.55
34 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55
35 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
36 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53
37 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53
38 INT338038 Gopc Regulation of Gene_expression of F2r 1 0.08 0 0.52
39 INT338045 F2r Regulation of Localization of Calca 1 0.03 0.05 0.52
40 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
41 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
42 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
43 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
44 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
45 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
46 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
47 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
48 INT132509 Binding of LEP and Cck 1 0.13 0.16 0.45
49 INT353331 Elane Positive_regulation of F2r 1 0.08 0.78 0.44
50 INT338059 Nrtn Positive_regulation of Gene_expression of F2r 1 0.12 0.45 0.41
51 INT323880 Binding of BMI1 and LEP 1 0.02 3.97 0.41
52 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
53 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
54 INT156237 Binding of F2r and Tnfsf14 1 0.02 1.14 0.4
55 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39
56 INT353332 Binding of F2r and Pawr 1 0.18 0.67 0.39
57 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38
58 INT278957 JAK3 Positive_regulation of Gene_expression of IL8 1 0.28 0.67 0.38
59 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
60 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
61 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38
62 INT303994 Il6 Positive_regulation of JAK2 1 0.03 0.41 0.37
63 INT278955 JAK3 Positive_regulation of Gene_expression of PRKCA 1 0.12 0.65 0.37
64 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37
65 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
66 INT278966 MAPK14 Positive_regulation of Gene_expression of LEP 1 0.16 0.62 0.36
67 INT278949 JAK3 Positive_regulation of Gene_expression of LEP 1 0.42 0.63 0.36
68 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
69 INT323885 LEP Regulation of Gene_expression of NOS2 1 0.26 1.07 0.35
70 INT213484 Binding of Lep and Pik3c3 1 0.01 0 0.35
71 INT156235 Tnfsf14 Positive_regulation of F2r 1 0.03 1.03 0.35
72 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
73 INT323870 LEP Regulation of Gene_expression of MMP13 1 0.21 1.76 0.33
74 INT303993 Lep Positive_regulation of Gene_expression of IL2 1 0.15 0.24 0.33
75 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33
76 INT353333 Positive_regulation of F2r Positive_regulation of Localization of Mif 1 0.46 0.26 0.32
77 INT353334 F2r Positive_regulation of Mif 1 0.68 0 0.32
78 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
79 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
80 INT278942 LEP Regulation of IL6 1 0.29 0.61 0.31
81 INT278939 LEP Regulation of IL8 1 0.13 0.61 0.31
82 INT213485 Lep Positive_regulation of Localization of Grin2a 1 0.19 0 0.31
83 INT353335 F2r Regulation of Positive_regulation of Mif 1 0.27 0.11 0.31
84 INT278969 LEP Regulation of PTGER2 1 0.03 0.6 0.31
85 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
86 INT226989 Lias Regulation of Gene_expression of Lep 1 0.10 0.91 0.3
87 INT278961 IL6 Regulation of Gene_expression of LEP 1 0.29 0.89 0.3
88 INT191799 PROC Negative_regulation of Binding of F2r 1 0.00 0.92 0.3
89 INT303983 Lep Positive_regulation of CXCL10 1 0.06 0.31 0.29
90 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29
91 INT303998 Lep Positive_regulation of Localization of IL1RAPL1 1 0.04 0.31 0.29
92 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29
93 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29
94 INT353336 F2r Regulation of Localization of Mif 1 0.23 0.24 0.28
95 INT303984 Lep Positive_regulation of Gene_expression of IL8 1 0.06 0.85 0.28
96 INT353330 F2r Positive_regulation of Positive_regulation of Mif 1 0.46 0 0.26
97 INT123663 F2R Positive_regulation of MAPK14 1 0.12 0.42 0.26
98 INT123662 Negative_regulation of F2R Positive_regulation of MAPK14 1 0.08 0.42 0.26
99 INT100531 Cck Positive_regulation of Lep 1 0.70 0.15 0.26
100 INT305686 Binding of Gfap and F2r 1 0.01 0 0.25
101 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25
102 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
103 INT191792 Binding of F2r and Serpinc1 1 0.00 3.74 0.24
104 INT125748 Binding of LEP and Gh 1 0.00 0.52 0.24
105 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23
106 INT303988 Lep Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.55 0.23
107 INT323883 BMI1 Regulation of LEP 1 0.02 2.39 0.23
108 INT123660 F2R Positive_regulation of PAR1 2 0.10 1.96 0.22
109 INT102937 Gnrh1 Positive_regulation of Gene_expression of Lep 1 0.50 0 0.22
110 INT110653 Lep Regulation of Localization of Cck 1 0.06 0.22 0.22
111 INT269180 LEP Positive_regulation of Localization of TNF 1 0.01 0.99 0.21
112 INT323873 LEP Regulation of Gene_expression of TIMP2 1 0.31 0.63 0.21
113 INT207185 Binding of Bmi1 and Lep 1 0.01 1.7 0.21
114 INT240536 Il12a Positive_regulation of Jak2 1 0.10 0.74 0.21
115 INT338042 F2r Positive_regulation of Localization of Prkca 1 0.06 0.1 0.2
116 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2
117 INT304001 Lep Negative_regulation of ICAM3 1 0.07 0.35 0.2
118 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2
119 INT303979 Lep Positive_regulation of ITGB2 1 0.11 0.35 0.2
120 INT256576 Lep Regulation of Localization of Ins1 1 0.57 2.08 0.2
121 INT303991 Lep Negative_regulation of SELL 1 0.04 0.35 0.2
122 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19
123 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19
124 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19
125 INT303964 Lep Positive_regulation of Icam1 1 0.24 0.35 0.19
126 INT333888 Lep Regulation of Localization of GAG 1 0.68 0.38 0.19
127 INT123664 F2R Positive_regulation of PAR4 1 0.03 0.51 0.19
128 INT226346 Binding of IL21 and Positive_regulation of Positive_regulation of JAK3 1 0.08 0.48 0.18
129 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18
130 INT303981 Lep Positive_regulation of Localization of CXCL1 1 0.02 0.34 0.18
131 INT195115 Gene_expression of Gopc Positive_regulation of Positive_regulation of F2r 1 0.17 1.67 0.18
132 INT195114 Gene_expression of Il1r1 Positive_regulation of Positive_regulation of F2r 1 0.38 1.67 0.18
133 INT226988 Lias Positive_regulation of Localization of Lep 1 0.08 0.3 0.17
134 INT303967 Lep Positive_regulation of Gene_expression of Icam1 1 0.24 0.58 0.16
135 INT303980 Lep Positive_regulation of Transcription of IL2 1 0.10 0.24 0.16
136 INT207144 F2r Positive_regulation of Pawr 1 0.14 0.51 0.16
137 INT207117 Binding of VEGFA and F2r 1 0.02 0.56 0.15
138 INT338040 Ctsg Positive_regulation of F2r 1 0.29 0 0.15
139 INT338052 F2r Positive_regulation of F2rl3 1 0.12 0 0.15
140 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14
141 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14
142 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14
143 INT139975 Binding of LEP and Prl 1 0.02 0.49 0.13
144 INT328060 LEP Positive_regulation of FAAH 1 0.06 0.7 0.13
145 INT346714 LEP Regulation of GALP 1 0.06 0.08 0.13
146 INT81179 LEP Regulation of Localization of GH1 1 0.11 0.91 0.12
147 INT214141 Binding of Lep and Lepr 1 0.32 0.82 0.12
148 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
149 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
150 INT164746 Binding of LEP and Adipoq 1 0.07 0.69 0.12
151 INT323871 LEP Regulation of Gene_expression of IGF1 1 0.14 1.19 0.11
152 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11
153 INT294742 Lep Positive_regulation of Localization of Icam1 1 0.15 0.48 0.11
154 INT163817 Lep Positive_regulation of Phosphorylation of Akt1 1 0.33 0.31 0.11
155 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11
156 INT303989 Lep Positive_regulation of IL12A 1 0.05 0.39 0.11
157 INT188358 Binding of Csf2 and Positive_regulation of Jak2 1 0.34 0.19 0.11
158 INT338041 F2r Positive_regulation of Pard3 1 0.15 0.05 0.11
159 INT169340 Binding of UGT8 and Jak2 1 0.36 0.15 0.11
160 INT303966 Lep Regulation of Il1 2 0.09 0.41 0.1
161 INT303990 Binding of Lep and Positive_regulation of Gene_expression of LPL 1 0.03 0.35 0.1
162 INT323879 LEP Regulation of SOAT1 1 0.15 1.15 0.1
163 INT204086 TNF Positive_regulation of Gene_expression of LEP 1 0.48 0.74 0.1
164 INT262255 Binding of APC and F2R 1 0.05 3 0.1
165 INT304000 Lep Negative_regulation of Positive_regulation of CASP8 1 0.04 0.25 0.1
166 INT123864 Lep Positive_regulation of Positive_regulation of Cck 1 0.45 0.1 0.09
167 INT242324 Lep Regulation of Gene_expression of Ucp1 1 0.58 1.47 0.09
168 INT142418 Lep Positive_regulation of Gene_expression of Ghrl 1 0.48 1.66 0.09
169 INT306794 Binding of LEP and COPD 1 0.15 3.94 0.09
170 INT213482 Lep Positive_regulation of Mapk1 1 0.06 0.08 0.09
171 INT300486 LEP Positive_regulation of ROS1 1 0.15 0.91 0.09
172 INT323868 LEP Regulation of Transcription of COL1A2 1 0.10 0.98 0.09
173 INT222545 Lep Negative_regulation of Nmb 1 0.04 0.52 0.08
174 INT123866 Lep Negative_regulation of Olfr544 1 0.00 0.09 0.08
175 INT303999 Lep Positive_regulation of Gene_expression of ITGA2 1 0.06 0.29 0.08
176 INT332287 LEP Positive_regulation of Phosphorylation of IRS1 1 0.20 1.48 0.08
177 INT323881 BMI1 Regulation of Gene_expression of LEP 1 0.03 1.09 0.08
178 INT323876 LEP Regulation of COL1A2 1 0.10 0.86 0.08
179 INT268325 Lep Positive_regulation of Ptgs2 1 0.09 0.39 0.08
180 INT303970 Lep Positive_regulation of Gene_expression of Itga2 1 0.09 0.29 0.08
181 INT294743 Lep Positive_regulation of Transcription of Il6 1 0.18 0.42 0.07
182 INT273374 Binding of JAK2 and STAT3 1 0.24 0 0.07
183 INT294740 Lep Positive_regulation of Transcription of Ccl2 1 0.08 0.42 0.07
184 INT273368 Negative_regulation of Binding of JAK2 and STAT3 1 0.28 0 0.07
185 INT323872 LEP Positive_regulation of Gene_expression of IGF1 1 0.35 0.77 0.07
186 INT303997 IL1RL1 Positive_regulation of Lep 1 0.01 0.2 0.07
187 INT242480 Ciapin1 Positive_regulation of Gene_expression of Jak2 1 0.27 1.05 0.07
188 INT273371 JAK2 Regulation of Protein_catabolism of SOCS1 1 0.01 0 0.06
189 INT200807 Jak2 Positive_regulation of Mvd 1 0.18 3.46 0.06
190 INT325769 Binding of EPOR and Positive_regulation of Phosphorylation of JAK2 1 0.66 0 0.06
191 INT273365 JAK2 Regulation of SOCS1 1 0.01 0 0.06
192 INT214153 Lep Regulation of Transcription of Nucb2 1 0.35 0.15 0.06
193 INT253377 Lep Negative_regulation of Phosphorylation of Prkaa2 1 0.24 1.24 0.06
194 INT323878 Binding of LEP and MMP13 1 0.17 0.77 0.05
195 INT238117 Positive_regulation of STAT3 Positive_regulation of Gene_expression of JAK2 1 0.11 0 0.05
196 INT267152 Binding of LEP and DDX12P 1 0.00 0.69 0.05
197 INT267157 LEP Positive_regulation of ADIPOQ 1 0.10 0.51 0.05
198 INT345965 Binding of Lep and al44 1 0.01 1.43 0.05
199 INT314135 Negative_regulation of Nos2 Positive_regulation of Lep 1 0.52 0.44 0.05
200 INT327821 GPRC6A Regulation of Gene_expression of Lep 1 0.00 0.5 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported for tyrosine phosphorylation of STAT protein. They are ordered first by their pain relevance and then by number of times they were reported in tyrosine phosphorylation of STAT protein. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
2 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
3 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
4 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
5 INT118512 Gene_expression of F2r 33 0.63 26.56 18.26
6 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
7 INT75908 Regulation of LEP 77 0.60 60.16 15.19
8 INT73641 Regulation of Lep 45 0.62 26.2 12.59
9 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
10 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
11 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
12 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
13 INT82082 Localization of Lep 63 0.81 26.41 8.56
14 INT75907 Binding of LEP 53 0.46 46.65 8.44
15 INT15592 Positive_regulation of F2r 17 0.67 8.66 8.36
16 INT117497 Positive_regulation of F2r 18 0.57 14.45 8.13
17 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71
18 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65
19 INT65356 Localization of LEP 46 0.79 41.17 5.43
20 INT91338 Binding of Lep 31 0.48 26.86 5.39
21 INT102935 Regulation of Lep 31 0.60 18.47 5.24
22 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
23 INT90852 Gene_expression of F2r 26 0.78 5.5 4.66
24 INT97391 Binding of Lep 18 0.48 8.97 4.47
25 INT163581 Localization of Lep 27 0.79 18.99 4.08
26 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
27 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75
28 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72
29 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
30 INT46754 Localization of F2r 7 0.78 2.36 3.24
31 INT58433 Negative_regulation of F2r 9 0.59 2.77 3.08
32 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65
33 INT82653 Regulation of F2r 8 0.36 3.78 2.62
34 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
35 INT150339 Gene_expression of F2R 10 0.73 3.59 2.46
36 INT113339 Binding of JAK2 6 0.40 5.31 2.4
37 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
38 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
39 INT82652 Negative_regulation of F2r 4 0.37 3.5 2.19
40 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16
41 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
42 INT83392 Transcription of Lep 6 0.54 5.07 2.04
43 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
44 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
45 INT278981 Negative_regulation of JAK3 5 0.46 2.12 1.69
46 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6
47 INT156231 Binding of F2r 9 0.23 3.78 1.57
48 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
49 INT214115 Regulation of Gene_expression of Lep 9 0.61 7.37 1.44
50 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
51 INT117498 Regulation of Positive_regulation of F2r 1 0.18 0.91 1.24
52 INT98976 Regulation of F2r 7 0.60 0.71 1.22
53 INT338033 Localization of F2r 1 0.41 0.62 1.2
54 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19
55 INT213465 Transcription of Lep 4 0.68 2.11 1.15
56 INT253813 Regulation of Negative_regulation of Lep 2 0.45 1.01 1.12
57 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
58 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04
59 INT278975 Gene_expression of JAK3 3 0.52 1.03 0.97
60 INT198049 Positive_regulation of JAK2 16 0.58 5.35 0.96
61 INT226480 Positive_regulation of JAK3 4 0.45 0.96 0.95
62 INT169336 Binding of Jak2 2 0.42 1.31 0.93
63 INT134040 Regulation of Jak2 3 0.41 1.07 0.92
64 INT195105 Negative_regulation of Gene_expression of F2r 3 0.37 1.41 0.91
65 INT184027 Phosphorylation of Jak2 6 0.82 2.58 0.87
66 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
67 INT134037 Positive_regulation of Phosphorylation of Jak2 1 0.46 0.25 0.86
68 INT333883 Positive_regulation of Positive_regulation of Lep 2 0.46 1.06 0.83
69 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81
70 INT237408 Positive_regulation of Positive_regulation of Jak2 1 0.28 1.56 0.79
71 INT195099 Positive_regulation of Gene_expression of F2r 7 0.57 5.31 0.78
72 INT82080 Regulation of Localization of Lep 2 0.45 1.36 0.76
73 INT353325 Positive_regulation of Localization of F2r 1 0.49 1.31 0.76
74 INT156533 Transcription of LEP 9 0.69 4.35 0.74
75 INT213471 Positive_regulation of Localization of Lep 4 0.48 2.65 0.74
76 INT113342 Positive_regulation of Phosphorylation of JAK2 2 0.66 2.58 0.72
77 INT62192 Regulation of Localization of F2r 2 0.60 0.59 0.7
78 INT207089 Regulation of Negative_regulation of F2r 1 0.17 1.49 0.62
79 INT353321 Regulation of Positive_regulation of F2r 1 0.60 0.6 0.62
80 INT101484 Regulation of Positive_regulation of Lep 3 0.45 1.68 0.61
81 INT345957 Positive_regulation of Binding of Lep 2 0.38 2.03 0.6
82 INT83391 Negative_regulation of Transcription of Lep 1 0.43 0.34 0.6
83 INT123672 Positive_regulation of F2R 9 0.47 0.77 0.58
84 INT306798 Protein_catabolism of LEP 1 0.65 2.45 0.58
85 INT191777 Binding of F2r 2 0.02 0.89 0.54
86 INT338026 Regulation of Localization of F2r 1 0.25 0.05 0.52
87 INT184062 Binding of Jak2 5 0.37 3.13 0.47
88 INT82819 Negative_regulation of Negative_regulation of LEP 3 0.56 2.22 0.46
89 INT345936 Regulation of JAK3 1 0.02 0.41 0.46
90 INT205890 Transcription of Jak2 1 0.41 0.22 0.43
91 INT102934 Positive_regulation of Regulation of Lep 2 0.50 0.55 0.42
92 INT323765 Negative_regulation of Binding of Lep 1 0.37 0.91 0.42
93 INT187726 Positive_regulation of Localization of LEP 5 0.50 5.31 0.41
94 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41
95 INT107462 Localization of Jak2 2 0.60 0.78 0.4
96 INT229697 Negative_regulation of Phosphorylation of Jak2 1 0.15 0.54 0.39
97 INT278972 Regulation of Negative_regulation of JAK3 1 0.21 0.36 0.37
98 INT200786 Positive_regulation of Gene_expression of Jak2 9 0.69 6.03 0.35
99 INT144981 Binding of F2R 3 0.36 1.66 0.35
100 INT205910 Negative_regulation of Positive_regulation of Jak2 1 0.33 0.26 0.35
101 INT353324 Negative_regulation of Positive_regulation of F2r 1 0.41 0.24 0.35
102 INT303962 Phosphorylation of Lep 2 0.80 5.2 0.31
103 INT213467 Negative_regulation of Localization of Lep 2 0.40 1.11 0.31
104 INT156534 Positive_regulation of Transcription of LEP 1 0.14 0.34 0.3
105 INT141781 Positive_regulation of Negative_regulation of LEP 1 0.46 0.37 0.29
106 INT62191 Negative_regulation of Localization of F2r 1 0.35 0 0.26
107 INT293346 Binding of JAK3 1 0.12 0.34 0.26
108 INT195091 Negative_regulation of Positive_regulation of F2r 1 0.48 1.69 0.25
109 INT303972 Positive_regulation of Gene_expression of JAK2 2 0.63 1.3 0.24
110 INT305682 Positive_regulation of Positive_regulation of F2r 1 0.03 0 0.24
111 INT150977 Regulation of Regulation of LEP 3 0.37 2.07 0.23
112 INT142417 Positive_regulation of Transcription of Lep 2 0.52 2.63 0.22
113 INT195112 Positive_regulation of Positive_regulation of F2r 1 0.41 0.97 0.18
114 INT163816 Phosphorylation of Lep 2 0.63 2.2 0.17
115 INT328811 Negative_regulation of Localization of Jak2 1 0.34 0.13 0.17
116 INT333880 Protein_catabolism of Lep 1 0.65 0.34 0.17
117 INT200802 Regulation of Jak2 5 0.61 2.86 0.16
118 INT157134 Regulation of Localization of LEP 1 0.09 0.5 0.16
119 INT333882 Regulation of Binding of Lep 1 0.45 0.07 0.16
120 INT204088 Regulation of Negative_regulation of LEP 1 0.59 1.16 0.16
121 INT261745 Regulation of F2R 1 0.43 0.22 0.16
122 INT261739 Regulation of Gene_expression of F2R 1 0.26 0.22 0.16
123 INT300489 Negative_regulation of Binding of LEP 1 0.41 1.12 0.15
124 INT98700 Regulation of Gene_expression of F2r 1 0.45 0 0.15
125 INT278979 Negative_regulation of Positive_regulation of LEP 2 0.40 0.81 0.14
126 INT207087 Negative_regulation of Binding of F2r 1 0.27 0.06 0.14
127 INT187723 Regulation of Positive_regulation of LEP 3 0.42 2.29 0.13
128 INT323898 Regulation of Phosphorylation of LEP 1 0.42 1.25 0.13
129 INT323895 Phosphorylation of LEP 1 0.76 1.23 0.13
130 INT157241 Negative_regulation of Localization of LEP 5 0.56 2.1 0.12
131 INT163815 Negative_regulation of Negative_regulation of Lep 1 0.43 0.32 0.12
132 INT278143 Positive_regulation of Negative_regulation of Jak2 1 0.16 0.54 0.11
133 INT226984 Regulation of Transcription of Lep 1 0.27 0.3 0.11
134 INT312354 Regulation of Gene_expression of JAK2 1 0.25 1.17 0.1
135 INT200792 Regulation of Gene_expression of Jak2 5 0.61 5.69 0.09
136 INT307530 Negative_regulation of Binding of F2R 1 0.03 0 0.09
137 INT184018 Negative_regulation of Protein_catabolism of Jak2 1 0.36 1.76 0.08
138 INT184023 Protein_catabolism of Jak2 1 0.61 1.75 0.08
139 INT187729 Positive_regulation of Binding of LEP 1 0.18 0.3 0.08
140 INT213475 Negative_regulation of Positive_regulation of Lep 2 0.40 1.79 0.07
141 INT145503 Protein_catabolism of F2r 1 0.66 0.46 0.07
142 INT195082 Regulation of Gene_expression of F2r 1 0.37 0.67 0.07
143 INT213466 Negative_regulation of Regulation of Lep 1 0.41 0 0.06
144 INT310747 Regulation of JAK2 2 0.33 1.58 0.05
145 INT238202 Negative_regulation of Localization of JAK2 1 0.09 0 0.05
146 INT238200 Localization of JAK2 1 0.16 0 0.05
147 INT261737 Transcription of F2R 1 0.50 0.31 0.05
148 INT353327 Transcription of F2r 1 0.67 0.21 0.03
149 INT238199 Positive_regulation of Positive_regulation of JAK2 1 0.10 0 0.03
150 INT191771 Positive_regulation of Gene_expression of F2r 1 0.01 0.31 0.03
151 INT253406 Negative_regulation of Positive_regulation of Lep 2 0.41 0.74 0
152 INT338031 Transcription of F2r 1 0.39 0 0
153 INT150408 Regulation of Regulation of Lep 1 0.27 0 0
154 INT305226 Negative_regulation of Phosphorylation of Lep 1 0.42 1.89 0
155 INT305239 Positive_regulation of Phosphorylation of Lep 1 0.43 1.09 0
156 INT238196 Negative_regulation of Binding of JAK2 1 0.09 0 0
157 INT332954 Regulation of Transcription of Lep 1 0.11 1.4 0
158 INT157243 Negative_regulation of Transcription of LEP 1 0.02 0.09 0
159 INT202420 Transcription of Jak2 1 0.56 0.91 0
160 INT350506 Protein_catabolism of JAK2 1 0.48 1.55 0
161 INT353323 Negative_regulation of Gene_expression of F2r 1 0.41 0 0
162 INT320539 Negative_regulation of Phosphorylation of JAK2 1 0.26 0.46 0
163 INT174279 Positive_regulation of Negative_regulation of Lep 1 0.46 0.16 0
164 INT261741 Negative_regulation of Positive_regulation of F2R 1 0.40 0 0
165 INT261743 Positive_regulation of Positive_regulation of F2R 1 0.44 0 0
166 INT309421 Positive_regulation of Regulation of Lep 1 0.41 0.61 0
167 INT288213 Positive_regulation of Negative_regulation of Lep 1 0.47 0.06 0
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