GO:0007263

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Name nitric oxide mediated signal transduction
Categary Process
Go Slim No
Go Link GO:0007263
Unique Molecular Interactions 298
Total Molecular Interactions 411
Total Single Events 2911
Pain Genes Associated 20

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nitric oxide mediated signal transduction. They are ordered first by their pain relevance and then by number of times they were reported for nitric oxide mediated signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
2 INT264950 Binding of FPR1 and BOC 1 0.11 0.67 1.55
3 INT44504 Mt1a Positive_regulation of Prl 1 0.37 0 1.48
4 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
5 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
6 INT13193 FPR1 Positive_regulation of ELANE 3 0.44 1.22 0.92
7 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
8 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87
9 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
10 INT56499 Neurod1 Positive_regulation of Maoa 1 0.47 0 0.8
11 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77
12 INT111194 Binding of NEUROD1 and Pck1 1 0.39 0 0.75
13 INT44502 Regulation of Mt1a Positive_regulation of Prl 1 0.14 0 0.74
14 INT155610 FPR1 Positive_regulation of Phosphorylation of SGSM3 1 0.04 0.68 0.71
15 INT81769 Binding of Chrna4 and Neurod1 1 0.35 0.07 0.69
16 INT335456 Binding of PDX1 and hb 1 0.02 2.59 0.66
17 INT209854 IL4 Positive_regulation of Gene_expression of CD36 1 0.51 1.2 0.65
18 INT264943 Negative_regulation of Binding of FPR1 and BOC 1 0.13 0.22 0.64
19 INT264946 Binding of FPR1 and GOPC 1 0.08 0.21 0.64
20 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64
21 INT154263 NEUROD1 Positive_regulation of Gene_expression of GAL 1 0.50 0.06 0.63
22 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
23 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
24 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
25 INT185809 Binding of PDX1 and SPP1 1 0.02 1.69 0.57
26 INT50883 Binding of AGTR2 and ALB 1 0.37 0.19 0.56
27 INT191762 FPR1 Positive_regulation of Gene_expression of IGKV1D-39 1 0.01 0.84 0.56
28 INT34459 AGT Negative_regulation of MBTPS1 1 0.01 0 0.54
29 INT167194 FPR1 Positive_regulation of Gene_expression of ITGAM 1 0.52 0.8 0.53
30 INT13191 FPR1 Positive_regulation of Localization of GUSB 1 0.31 0 0.53
31 INT13192 FPR1 Positive_regulation of Localization of LRBA 1 0.47 0 0.53
32 INT132438 Binding of AGT and OXTR 1 0.08 1.03 0.53
33 INT119745 NEUROD1 Regulation of Gene_expression of BHLHE22 1 0.11 0.26 0.53
34 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52
35 INT95042 Binding of NEUROD1 and Olr1246 1 0.02 0.23 0.51
36 INT263973 Binding of CSF2 and FPR1 1 0.08 0.81 0.51
37 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
38 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
39 INT116863 Apoe Negative_regulation of Hand1 1 0.37 0.69 0.5
40 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
41 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
42 INT14992 FPR1 Positive_regulation of Localization of MPO 2 0.56 1.1 0.49
43 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
44 INT14993 MET Positive_regulation of Localization of FPR1 1 0.50 0.44 0.49
45 INT264948 BOC Negative_regulation of FPR1 1 0.13 0.18 0.48
46 INT264949 BOC Negative_regulation of Localization of FPR1 1 0.13 0.18 0.48
47 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46
48 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
49 INT12702 Regulation of Binding of FPR1 and GUSB 1 0.43 0.18 0.44
50 INT142608 Apoe Regulation of Gene_expression of Il6 1 0.25 1.01 0.44
51 INT56631 Negative_regulation of FPR1 Positive_regulation of ELANE 1 0.38 0.54 0.44
52 INT264945 GOPC Positive_regulation of Positive_regulation of FPR1 1 0.10 0.2 0.44
53 INT167154 FPR1 Positive_regulation of ING1 1 0.18 0.18 0.44
54 INT12703 Binding of FPR1 and GUSB 1 0.36 0.18 0.44
55 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43
56 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
57 INT56577 Mt1a Positive_regulation of Localization of Gnrh1 1 0.04 0 0.43
58 INT230437 Binding of PDX1 and HRCT1 1 0.04 2.45 0.43
59 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
60 INT72346 FPR1 Regulation of Localization of SFTPA1 1 0.02 0.24 0.42
61 INT171185 Binding of NEUROD1 and ACOT1 1 0.01 0.37 0.42
62 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42
63 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42
64 INT146274 Binding of Rasd1 and Nos1ap 1 0.33 0.18 0.41
65 INT146273 Binding of Nos1 and Rasd1 1 0.34 0.18 0.41
66 INT209858 TNF Regulation of Transcription of CD36 1 0.27 0 0.4
67 INT56876 Regulation of Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
68 INT182489 Gene_expression of AGTR2 Positive_regulation of Gene_expression of AGTR1 1 0.26 0.92 0.4
69 INT56875 Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
70 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
71 INT70010 Binding of Neurod1 and Insrr 1 0.01 0.11 0.37
72 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37
73 INT230438 Binding of PDX1 and HAUS7 1 0.02 2.29 0.35
74 INT167156 FPR1 Positive_regulation of MAPK1 1 0.18 0.09 0.35
75 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
76 INT322208 HRCT1 Positive_regulation of PDX1 1 0.01 1.31 0.34
77 INT335455 Negative_regulation of Binding of PDX1 and hb 1 0.02 1.3 0.33
78 INT167155 FPR1 Positive_regulation of Phosphorylation of MAPK1 1 0.18 0.17 0.33
79 INT209855 NFE2L2 Positive_regulation of Gene_expression of CD36 1 0.27 0.72 0.32
80 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31
81 INT334024 Ccl25 Positive_regulation of Gene_expression of CD36 1 0.31 0.36 0.31
82 INT335446 Binding of PDX1 and COPD 1 0.02 1.99 0.3
83 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
84 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28
85 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28
86 INT185806 Binding of PDX1 and MMP7 1 0.02 0.84 0.28
87 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28
88 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
89 INT334023 pma Positive_regulation of Gene_expression of CD36 1 0.04 0.31 0.28
90 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27
91 INT298277 Pou4f1 Negative_regulation of Gene_expression of Neurod1 1 0.58 0.48 0.27
92 INT167488 Binding of NEUROD1 and GGNBP2 1 0.08 0 0.27
93 INT68298 Binding of Neurod1 and Abt1 1 0.24 0 0.26
94 INT162502 NEUROD1 Regulation of CYP1A1 2 0.07 0.09 0.25
95 INT162501 NEUROD1 Regulation of CYP1A2 2 0.22 0.09 0.25
96 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25
97 INT209849 TNF Positive_regulation of Gene_expression of CD36 1 0.69 0.18 0.25
98 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
99 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
100 INT41588 Binding of AGT and Lhb 1 0.00 0 0.24
101 INT78295 Binding of Ptpra and Apoe 1 0.42 0.25 0.24
102 INT41589 Binding of AGT and Prl 1 0.00 0 0.24
103 INT198643 CD36 Positive_regulation of CADM1 1 0.01 1.07 0.24
104 INT297334 Gnb5 Regulation of Apoe 1 0.09 0.83 0.24
105 INT335447 PDX1 Regulation of Gene_expression of COPD 1 0.02 1.03 0.24
106 INT78294 Negative_regulation of Binding of Ptpra and Apoe 1 0.48 0.25 0.24
107 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24
108 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
109 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23
110 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
111 INT209856 IL1A Negative_regulation of Transcription of CD36 1 0.26 0.1 0.22
112 INT209848 TNF Positive_regulation of CD36 1 0.46 0.24 0.22
113 INT20403 FPR1 Positive_regulation of Itgax 1 0.02 0.22 0.22
114 INT20392 FPR1 Positive_regulation of CR1 1 0.04 0.22 0.22
115 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21
116 INT78263 Npy Positive_regulation of Npy2r 1 0.04 0 0.21
117 INT209851 TGFB2 Negative_regulation of Gene_expression of CD36 1 0.16 0.16 0.21
118 INT146271 Nos1ap Positive_regulation of Positive_regulation of Rasd1 1 0.34 0.08 0.21
119 INT209857 IL10 Negative_regulation of Gene_expression of CD36 1 0.31 0.16 0.2
120 INT203527 Pou4f1 Negative_regulation of Neurod1 1 0.32 0.54 0.2
121 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
122 INT18966 TNF Positive_regulation of NEUROD1 1 0.53 0.83 0.2
123 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
124 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19
125 INT252330 Binding of Cd36 and Cd47 2 0.10 0.72 0.19
126 INT244054 Prkaca Regulation of Neurod1 1 0.02 0.06 0.19
127 INT229223 Binding of AGT and FAS 1 0.08 0.91 0.17
128 INT36568 AGT Positive_regulation of FBF1 1 0.39 0.5 0.17
129 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
130 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17
131 INT233904 NLRP3 Positive_regulation of AGT 1 0.06 0.81 0.17
132 INT229224 Positive_regulation of Binding of AGT and FAS 1 0.09 0.92 0.17
133 INT36567 Negative_regulation of AGT Positive_regulation of FBF1 1 0.36 0.5 0.17
134 INT232005 Binding of Cd36 and Tsp1 2 0.25 1.81 0.16
135 INT111863 Negative_regulation of Binding of AGT and LNPEP 1 0.09 0 0.16
136 INT122528 Apoe Regulation of Eno2 1 0.05 0.29 0.16
137 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16
138 INT111861 Binding of AGT and LNPEP 1 0.07 0 0.16
139 INT297345 Apoe Negative_regulation of Csf2 1 0.17 0.66 0.16
140 INT34484 FPR1 Positive_regulation of Localization of MMP2 1 0.36 0.15 0.15
141 INT347071 Negative_regulation of REN Negative_regulation of Positive_regulation of AGT 1 0.35 0.44 0.14
142 INT34430 AGT Positive_regulation of Localization of POMC 1 0.30 0.31 0.14
143 INT170817 CMA1 Positive_regulation of Gene_expression of AGT 1 0.19 1.41 0.14
144 INT344946 AGT Regulation of Negative_regulation of ACE 1 0.21 0.61 0.14
145 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14
146 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14
147 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13
148 INT59808 Binding of AGT and PLCB1 1 0.02 0 0.13
149 INT59809 AGT Positive_regulation of PLCB1 1 0.03 0 0.13
150 INT335460 FPR1 Positive_regulation of PIK3CD 1 0.17 0 0.13
151 INT59810 ADRA1D Positive_regulation of AGT 1 0.01 0 0.13
152 INT10731 NEUROD1 Regulation of CD4 1 0.42 1.3 0.12
153 INT10732 NEUROD1 Regulation of CD9 1 0.49 1.29 0.12
154 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
155 INT182496 AGT Positive_regulation of Phosphorylation of STAT3 1 0.03 0.79 0.12
156 INT345290 AGT Positive_regulation of NOX1 1 0.00 1.11 0.12
157 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11
158 INT352497 AGT Positive_regulation of Binding of CRS 1 0.14 0.87 0.11
159 INT328370 Binding of CD36 and Fabp1 1 0.01 0.64 0.11
160 INT281905 Binding of AGTR2 and NOS3 1 0.08 0.37 0.1
161 INT208361 Positive_regulation of Binding of Apoe and Hdl1 1 0.12 1.22 0.1
162 INT139558 Chrna4 Regulation of Neurod1 1 0.17 0 0.1
163 INT297546 Neurod1 Regulation of Notch1 1 0.05 0.2 0.1
164 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1
165 INT281912 Binding of AGTR2 and ANG 1 0.13 0.37 0.1
166 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
167 INT171188 Positive_regulation of Binding of NEUROD1 and TNIP1 1 0.08 0 0.1
168 INT139557 Chrna4 Regulation of Gene_expression of Neurod1 1 0.17 0 0.1
169 INT148102 AGT Positive_regulation of Gene_expression of STK24 1 0.37 0.96 0.1
170 INT297346 Apoe Negative_regulation of Localization of TNF 1 0.48 0.26 0.1
171 INT171184 Binding of NEUROD1 and TNIP1 1 0.06 0 0.1
172 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1
173 INT233907 Positive_regulation of Binding of AGTR2 and NLRP3 1 0.01 1.09 0.08
174 INT254641 CGA Positive_regulation of AGT 1 0.17 1.51 0.08
175 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
176 INT233906 Binding of AGTR2 and NLRP3 1 0.01 1.09 0.08
177 INT301613 Binding of Fabp4 and Cd36 1 0.05 0.38 0.08
178 INT267969 Binding of AGT and TRPV1 1 0.00 0.44 0.08
179 INT267970 Negative_regulation of Binding of AGT and TRPV1 1 0.00 0.44 0.08
180 INT254639 CGA Positive_regulation of Gene_expression of AGT 1 0.18 1.51 0.08
181 INT301614 Binding of Slc27a1 and Cd36 1 0.09 0.38 0.08
182 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07
183 INT297330 Apoe Positive_regulation of Gene_expression of Nos2 1 0.26 0.34 0.07
184 INT20393 Negative_regulation of FPR1 Positive_regulation of CR1 1 0.03 0.07 0.07
185 INT172382 AGT Positive_regulation of Localization of EDN1 1 0.03 0.34 0.07
186 INT281900 Positive_regulation of Binding of AGT and AGTR1 1 0.12 0.16 0.07
187 INT308665 Binding of Apoe and Gopc 1 0.02 0.49 0.07
188 INT20404 Negative_regulation of FPR1 Positive_regulation of Itgax 1 0.02 0.07 0.07
189 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07
190 INT50078 Binding of APOE and NPPA 1 0.30 0.42 0.07
191 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
192 INT281909 Binding of AGT and AGTR1 1 0.09 0.16 0.06
193 INT334027 Ccl25 Regulation of Gene_expression of CD36 1 0.14 0.24 0.05
194 INT317245 Binding of Npy2r and Pyy 1 0.09 0 0.05
195 INT88773 Positive_regulation of Binding of AGT and Agtrap 1 0.01 0.88 0.05
196 INT287223 Pdx1 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
197 INT334026 pma Regulation of Gene_expression of CD36 1 0.02 0.16 0.05
198 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05
199 INT317246 Binding of Npy2r and Npy 1 0.08 0 0.05
200 INT208356 Hdl1 Positive_regulation of Apoe 1 0.12 1.25 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported for nitric oxide mediated signal transduction. They are ordered first by their pain relevance and then by number of times they were reported in nitric oxide mediated signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23
2 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
3 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
4 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
5 INT171060 Gene_expression of PDX1 72 0.75 72.57 17.97
6 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
7 INT142621 Positive_regulation of Gene_expression of CD36 38 0.70 15.18 13.4
8 INT14997 Positive_regulation of FPR1 21 0.66 9.82 13.2
9 INT3962 Regulation of AGT 50 0.62 20.96 13.01
10 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23
11 INT398 Localization of AGT 45 0.78 16.97 11.54
12 INT8065 Binding of AGT 54 0.48 20.54 10.85
13 INT6651 Localization of FPR1 18 0.73 3.27 9.9
14 INT149138 Binding of PDX1 27 0.37 32.62 9.33
15 INT15991 Gene_expression of FPR1 27 0.59 8.22 9.01
16 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89
17 INT209866 Regulation of Gene_expression of CD36 27 0.60 10.04 8.42
18 INT12463 Binding of FPR1 21 0.48 3.16 7.98
19 INT6652 Negative_regulation of FPR1 11 0.42 5.29 7.41
20 INT64370 Gene_expression of Neurod1 22 0.75 5.19 7.1
21 INT197493 Localization of Apoe 61 0.79 27.48 7.06
22 INT27916 Gene_expression of Mt1a 6 0.47 4.4 7.04
23 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94
24 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72
25 INT6097 Negative_regulation of NEUROD1 30 0.57 9.71 6.24
26 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
27 INT35780 Positive_regulation of Mt1a 9 0.55 4.9 6.08
28 INT6098 Binding of NEUROD1 17 0.47 3.4 5.99
29 INT63042 Binding of Apoe 59 0.48 31.23 5.88
30 INT164656 Negative_regulation of Gene_expression of CD36 24 0.57 6.51 5.39
31 INT127914 Gene_expression of AGTR2 23 0.68 26.87 4.69
32 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69
33 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
34 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75
35 INT12707 Negative_regulation of Binding of FPR1 9 0.59 1.45 3.72
36 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71
37 INT20011 Regulation of NEUROD1 10 0.44 3.83 3.53
38 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
39 INT26702 Transcription of CD36 17 0.70 3.56 3.49
40 INT28390 Negative_regulation of Mt1a 4 0.36 1.13 3.39
41 INT133214 Regulation of PDX1 9 0.34 10.26 3.36
42 INT111369 Transcription of Mt1a 4 0.68 1.01 3.35
43 INT72141 Binding of Apoe 11 0.37 10.91 3.27
44 INT97710 Localization of Apoe 1 0.79 7.18 3.2
45 INT78253 Gene_expression of Npy2r 7 0.77 1.49 2.89
46 INT39856 Binding of Neurod1 8 0.47 1.44 2.88
47 INT171058 Negative_regulation of PDX1 5 0.32 9.31 2.72
48 INT50080 Binding of APOE 38 0.45 29.61 2.67
49 INT111368 Transcription of Mt2A 1 0.69 0.94 2.66
50 INT63238 Gene_expression of Mt1 27 0.65 10.86 2.53
51 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52
52 INT17857 Negative_regulation of Gene_expression of AGT 25 0.46 21.16 2.45
53 INT15993 Regulation of FPR1 8 0.40 1.24 2.42
54 INT198662 Positive_regulation of CD36 14 0.68 7.73 2.36
55 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27
56 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27
57 INT57664 Gene_expression of Npy2r 4 0.19 1.41 2.26
58 INT142265 Regulation of Apoe 20 0.60 9.52 2.23
59 INT82048 Positive_regulation of Neurod1 7 0.49 2.39 2.13
60 INT26706 Positive_regulation of Transcription of CD36 8 0.68 3.32 2.12
61 INT84060 Regulation of Apoe 4 0.62 3.33 2.05
62 INT94285 Negative_regulation of CD36 10 0.43 6.61 1.98
63 INT199084 Gene_expression of Cd36 31 0.53 16.94 1.94
64 INT133269 Positive_regulation of PDX1 10 0.54 9.77 1.9
65 INT171059 Localization of PDX1 8 0.56 6.7 1.9
66 INT100009 Phosphorylation of FPR1 3 0.38 1.02 1.9
67 INT13999 Positive_regulation of Positive_regulation of NEUROD1 5 0.67 4.07 1.86
68 INT326006 Regulation of Gene_expression of Mt1a 1 0.07 0.55 1.79
69 INT326007 Negative_regulation of Gene_expression of Mt1a 1 0.07 1.32 1.68
70 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
71 INT264966 Positive_regulation of Localization of FPR1 1 0.29 0.62 1.61
72 INT65602 Negative_regulation of Neurod1 7 0.42 2.52 1.55
73 INT111367 Regulation of Transcription of Mt2A 1 0.44 0.65 1.5
74 INT111366 Regulation of Transcription of Mt1a 1 0.43 0.65 1.5
75 INT64371 Positive_regulation of Gene_expression of Neurod1 4 0.64 1.56 1.45
76 INT66527 Positive_regulation of Npy2r 2 0.31 0.47 1.44
77 INT9269 Regulation of Mt1a 3 0.36 0 1.43
78 INT34768 Negative_regulation of Negative_regulation of AGT 10 0.25 2.79 1.42
79 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4
80 INT8067 Negative_regulation of Binding of AGT 12 0.25 10.33 1.39
81 INT27356 Localization of NEUROD1 8 0.78 3.44 1.39
82 INT14998 Negative_regulation of Localization of FPR1 3 0.42 1.47 1.38
83 INT97716 Transcription of Apoe 3 0.53 2.61 1.36
84 INT73938 Gene_expression of Cd36 20 0.76 12.27 1.35
85 INT12704 Regulation of Binding of FPR1 3 0.23 0.45 1.34
86 INT215380 Positive_regulation of Gene_expression of Cd36 12 0.47 8.51 1.3
87 INT183065 Positive_regulation of Gene_expression of PDX1 7 0.54 6.58 1.29
88 INT11241 Transcription of AGT 4 0.52 1.83 1.27
89 INT18971 Positive_regulation of Gene_expression of NEUROD1 8 0.67 1.91 1.23
90 INT155946 Positive_regulation of Mt1 7 0.45 4.31 1.23
91 INT97715 Regulation of Gene_expression of Apoe 3 0.62 1.98 1.23
92 INT113336 Positive_regulation of Gene_expression of Apoe 3 0.70 1.79 1.23
93 INT142530 Negative_regulation of Positive_regulation of Mt2A 1 0.43 0.36 1.23
94 INT142531 Positive_regulation of Mt2A 1 0.70 0.36 1.22
95 INT47644 Positive_regulation of Localization of AGT 4 0.45 1.24 1.2
96 INT23922 Positive_regulation of Positive_regulation of FPR1 2 0.44 1.58 1.15
97 INT115621 Positive_regulation of Binding of AGT 1 0.02 0 1.15
98 INT97369 Regulation of Gene_expression of NEUROD1 1 0.26 0.25 1.12
99 INT217390 Negative_regulation of Positive_regulation of Apoe 3 0.37 1.95 1.05
100 INT94210 Regulation of Neurod1 2 0.33 0.07 1.04
101 INT264974 Positive_regulation of Negative_regulation of FPR1 1 0.27 0.1 1.02
102 INT326005 Positive_regulation of Positive_regulation of Mt1a 1 0.08 0.48 0.97
103 INT326008 Positive_regulation of Negative_regulation of Mt1a 1 0.08 0.48 0.97
104 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97
105 INT66526 Regulation of Positive_regulation of Npy2r 1 0.20 0 0.96
106 INT73939 Negative_regulation of Cd36 7 0.57 6.3 0.95
107 INT80315 Binding of Npy2r 2 0.48 0.53 0.95
108 INT51906 Negative_regulation of Gene_expression of NEUROD1 4 0.57 1.56 0.91
109 INT182513 Regulation of AGTR2 4 0.14 4.31 0.91
110 INT44499 Localization of Mt1a 2 0.59 0.12 0.9
111 INT146261 Regulation of Rasd1 1 0.35 0.33 0.84
112 INT100010 Negative_regulation of Phosphorylation of FPR1 2 0.20 0.25 0.82
113 INT178485 Binding of Cd36 11 0.22 6.65 0.8
114 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8
115 INT80316 Positive_regulation of Npy2r 3 0.31 0.28 0.78
116 INT52187 Regulation of Binding of NEUROD1 1 0.44 0 0.77
117 INT21943 Positive_regulation of Positive_regulation of AGT 6 0.46 3.29 0.75
118 INT34715 Regulation of Regulation of AGT 2 0.37 0.96 0.75
119 INT44501 Regulation of Localization of Mt1a 1 0.30 0 0.75
120 INT197495 Negative_regulation of Localization of Apoe 6 0.43 2.19 0.73
121 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72
122 INT27077 Binding of CD36 4 0.37 2.14 0.72
123 INT270428 Negative_regulation of Binding of APOE 2 0.41 1.16 0.7
124 INT113335 Regulation of Transcription of Apoe 1 0.27 0.51 0.7
125 INT326004 Binding of Mt1a 1 0.06 0.24 0.68
126 INT34769 Regulation of Gene_expression of AGT 3 0.19 1.39 0.67
127 INT175580 Localization of APOE 10 0.76 18.84 0.65
128 INT128728 Localization of Npy2r 3 0.80 0 0.65
129 INT78255 Transcription of Npy2r 1 0.12 0.59 0.62
130 INT97708 Regulation of Localization of Apoe 1 0.61 2.06 0.62
131 INT2292 Protein_catabolism of FPR1 1 0.01 0 0.58
132 INT113334 Positive_regulation of Positive_regulation of Apoe 1 0.50 0.6 0.56
133 INT80317 Positive_regulation of Binding of Npy2r 1 0.16 0.34 0.56
134 INT133968 Binding of Pdx1 1 0.32 0.16 0.55
135 INT142620 Regulation of CD36 6 0.62 0.72 0.54
136 INT197322 Protein_catabolism of Apoe 6 0.71 3.52 0.51
137 INT233916 Positive_regulation of AGTR2 5 0.37 3.67 0.51
138 INT14995 Negative_regulation of Positive_regulation of FPR1 2 0.41 0.44 0.5
139 INT335452 Regulation of Gene_expression of PDX1 1 0.05 2.56 0.5
140 INT217370 Phosphorylation of Apoe 2 0.63 1.8 0.49
141 INT47645 Negative_regulation of Localization of AGT 2 0.11 1.09 0.49
142 INT74871 Negative_regulation of Gene_expression of Mt1 3 0.26 1.8 0.48
143 INT274343 Localization of Mt1 1 0.11 0.84 0.48
144 INT146255 Positive_regulation of Rasd1 1 0.39 0.22 0.48
145 INT182508 Positive_regulation of Gene_expression of AGTR2 1 0.26 3.13 0.46
146 INT96816 Regulation of APOE 8 0.45 6.62 0.44
147 INT76845 Regulation of Gene_expression of Neurod1 2 0.44 0.28 0.44
148 INT350910 Regulation of Positive_regulation of Mt1 1 0.12 0.51 0.44
149 INT154042 Localization of Neurod1 1 0.02 0.08 0.44
150 INT33017 Negative_regulation of Protein_catabolism of AGT 3 0.37 0 0.42
151 INT280670 Localization of Cd36 1 0.61 0.65 0.41
152 INT280675 Regulation of Localization of Cd36 1 0.32 0.57 0.41
153 INT60952 Negative_regulation of Regulation of NEUROD1 1 0.42 0.3 0.41
154 INT60953 Negative_regulation of Negative_regulation of NEUROD1 1 0.41 0.3 0.41
155 INT97712 Negative_regulation of Transcription of Apoe 1 0.43 1.05 0.4
156 INT167163 Positive_regulation of Phosphorylation of FPR1 1 0.22 0.1 0.4
157 INT126571 Positive_regulation of Cd36 3 0.41 1.19 0.38
158 INT182510 Negative_regulation of Gene_expression of AGTR2 1 0.23 0.78 0.37
159 INT156490 Protein_catabolism of Neurod1 1 0.34 0.16 0.37
160 INT51266 Transcription of Neurod1 2 0.69 0.19 0.35
161 INT95605 Regulation of Binding of AGT 3 0.44 0.2 0.34
162 INT27928 Phosphorylation of AGT 1 0.52 0.15 0.34
163 INT47995 Positive_regulation of Regulation of NEUROD1 1 0.45 0.68 0.34
164 INT27929 Negative_regulation of Phosphorylation of AGT 1 0.27 0.15 0.34
165 INT131542 Negative_regulation of Gene_expression of APOE 6 0.40 3.92 0.33
166 INT185840 Positive_regulation of Localization of PDX1 2 0.27 0.78 0.33
167 INT24861 Regulation of Positive_regulation of NEUROD1 2 0.44 0.39 0.33
168 INT156399 Regulation of Pdx1 1 0.00 0.96 0.33
169 INT256615 Positive_regulation of Gene_expression of FPR1 4 0.29 1.27 0.32
170 INT10801 Localization of CD36 3 0.73 2.12 0.32
171 INT209865 Negative_regulation of Transcription of CD36 1 0.57 0.15 0.32
172 INT311128 Positive_regulation of Regulation of Apoe 1 0.30 0.3 0.3
173 INT233881 Positive_regulation of Cd36 8 0.48 4.68 0.29
174 INT175687 Transcription of Apoe 4 0.72 2.12 0.29
175 INT182515 Binding of AGTR2 3 0.32 2.4 0.29
176 INT96815 Regulation of Gene_expression of APOE 2 0.62 1.1 0.29
177 INT104311 Positive_regulation of Transcription of NEUROD1 1 0.49 0.28 0.29
178 INT182509 Regulation of Gene_expression of AGTR2 1 0.24 1.72 0.29
179 INT104309 Transcription of NEUROD1 1 0.69 0.28 0.29
180 INT146268 Negative_regulation of Rasd1 1 0.33 0.15 0.27
181 INT146265 Positive_regulation of Gene_expression of Rasd1 1 0.37 0.14 0.27
182 INT97711 Positive_regulation of Transcription of Apoe 1 0.46 1.06 0.27
183 INT3331 Positive_regulation of Protein_catabolism of AGT 1 0.33 0 0.27
184 INT49942 Positive_regulation of Pdx1 5 0.02 1.24 0.26
185 INT254756 Regulation of Positive_regulation of Apoe 1 0.20 0.22 0.26
186 INT146260 Gene_expression of Rasd1 1 0.61 0.14 0.26
187 INT332230 Regulation of Pdx1 1 0.01 0.99 0.25
188 INT59871 Negative_regulation of Gene_expression of FPR1 2 0.22 0.88 0.23
189 INT323964 Negative_regulation of Binding of Apoe 1 0.39 0.35 0.22
190 INT198892 Regulation of Binding of Apoe 6 0.45 2.94 0.21
191 INT269264 Regulation of Mt1 6 0.21 2.71 0.2
192 INT209345 Negative_regulation of AGTR2 5 0.17 4.83 0.2
193 INT193810 Phosphorylation of APOE 2 0.27 1.13 0.2
194 INT64107 Negative_regulation of Npy2r 1 0.12 0 0.2
195 INT82049 Negative_regulation of Positive_regulation of Neurod1 1 0.41 0.61 0.18
196 INT180524 Regulation of Gene_expression of FPR1 2 0.20 0.45 0.17
197 INT254754 Regulation of Localization of Apoe 1 0.20 0.39 0.17
198 INT48771 Positive_regulation of Localization of NEUROD1 2 0.49 1.5 0.16
199 INT254755 Positive_regulation of Transcription of Apoe 1 0.16 0.41 0.16
200 INT326469 Positive_regulation of Negative_regulation of AGTR2 1 0.09 2.96 0.16
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