GO:0007271

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Name synaptic transmission, cholinergic
Categary Process
Go Slim No
Go Link GO:0007271
Unique Molecular Interactions 168
Total Molecular Interactions 206
Total Single Events 3012
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for synaptic transmission, cholinergic. They are ordered first by their pain relevance and then by number of times they were reported for synaptic transmission, cholinergic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
2 INT120323 Slc5a7 Negative_regulation of Flvcr2 1 0.02 0.43 1.1
3 INT131173 Chrna7 Positive_regulation of Localization of Abat 1 0.10 0 1.01
4 INT251704 Ache Regulation of Gene_expression of Acot1 1 0.08 1.68 0.87
5 INT113250 Olr1259 Negative_regulation of Ache 1 0.01 0.38 0.83
6 INT140280 Negative_regulation of Binding of Adora2a and Grina 1 0.21 0.64 0.82
7 INT140281 Binding of Adora2a and Grina 1 0.19 0.64 0.82
8 INT72017 Binding of Adora2a and Ptprg 2 0.07 0 0.77
9 INT76498 Binding of Tacr1 and Adora2a 1 0.09 0 0.77
10 INT46246 Tpsg1 Regulation of Ache 1 0.15 0.06 0.76
11 INT46247 Tpsg1 Regulation of Binding of Ache 1 0.15 0.06 0.76
12 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
13 INT82040 Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.11 0 0.75
14 INT23681 Negative_regulation of Binding of Stx3 and Chrna7 1 0.00 0 0.75
15 INT23680 Binding of Stx3 and Chrna7 1 0.00 0 0.75
16 INT18447 Binding of Ache and Chat 2 0.33 0.33 0.73
17 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
18 INT82041 Positive_regulation of Adora2a Positive_regulation of Phosphorylation of Ppp1r1b 1 0.12 0 0.72
19 INT43663 Binding of Chrna7 and Rac2 1 0.01 0 0.72
20 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
21 INT81769 Binding of Chrna4 and Neurod1 1 0.35 0.07 0.69
22 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
23 INT239501 Binding of Adora2a and Mtx1 1 0.24 0.95 0.64
24 INT23679 Chrna7 Regulation of Binding of Stx3 1 0.00 0 0.56
25 INT215644 Binding of Drd2 and Adora2a 1 0.03 0.23 0.55
26 INT167484 Binding of CHRNE and GGNBP2 1 0.02 0 0.5
27 INT88080 Binding of Chrna4 and Psmb6 1 0.03 0.56 0.46
28 INT162929 NQO1 Negative_regulation of Phosphorylation of AKT1 1 0.41 1 0.46
29 INT83111 LIAS Negative_regulation of Binding of Chrna7 1 0.02 0 0.45
30 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
31 INT89666 Binding of Adora2a and Drd2 1 0.54 0.4 0.42
32 INT302871 Negative_regulation of Adora2a Positive_regulation of Phosphorylation of Th 1 0.26 0.12 0.4
33 INT85037 Binding of Cct2 and Chrna3 1 0.00 0.15 0.38
34 INT239503 Binding of Adora2a and Aes 1 0.24 0.85 0.35
35 INT115162 Adora2a Regulation of Gene_expression of Jun 1 0.49 0.36 0.34
36 INT46788 Chrna7 Positive_regulation of G6pd 1 0.50 0 0.33
37 INT51630 Binding of ACHE and OPRM1 1 0.11 0 0.33
38 INT51628 Binding of ACHE and DRD3 1 0.15 0 0.33
39 INT115161 Adora2a Regulation of Gene_expression of Cpe 1 0.04 0.36 0.33
40 INT31754 Prl Negative_regulation of Bche 1 0.35 0 0.32
41 INT31753 Prl Regulation of Bche 1 0.37 0 0.32
42 INT254122 Adora2a Regulation of Aliq1 1 0.01 0.85 0.3
43 INT281797 Positive_regulation of Chrna4 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.43 0.3
44 INT59682 Hps6 Positive_regulation of Binding of Chrna7 1 0.02 0 0.29
45 INT59683 Binding of Chrna7 and Evi2a 1 0.03 0 0.25
46 INT160225 Acot1 Negative_regulation of Ache 1 0.28 2.18 0.25
47 INT88555 Adora2a Negative_regulation of Vegfc 1 0.00 0.17 0.25
48 INT23626 Ache Regulation of Mir343 1 0.17 0 0.24
49 INT143972 Chrna7 Negative_regulation of Gene_expression of Trpv1 1 0.01 0.18 0.24
50 INT281798 CFD Regulation of Positive_regulation of Chrna4 1 0.01 0.24 0.24
51 INT162931 TXNRD1 Negative_regulation of Phosphorylation of NQO1 1 0.13 0.5 0.23
52 INT224130 Positive_regulation of Adora2a Positive_regulation of ADCY1 1 0.01 0.11 0.22
53 INT224087 Adrbk1 Negative_regulation of Adora2a 1 0.10 0.13 0.22
54 INT72015 Binding of Adora2a and Gnai2 1 0.01 0 0.21
55 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2
56 INT143974 Chrna7 Positive_regulation of Vti1b 1 0.17 0.16 0.2
57 INT159720 Slc5a7 Regulation of Gene_expression of Acot1 1 0.12 0 0.19
58 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19
59 INT159722 Slc5a7 Positive_regulation of Gene_expression of Acot1 1 0.12 0 0.19
60 INT326940 Chrm3 Positive_regulation of Nalcn 1 0.06 0.21 0.19
61 INT47426 Chrna7 Positive_regulation of Localization of Ldha 1 0.05 0 0.18
62 INT47427 Chrna7 Positive_regulation of Ldha 1 0.05 0 0.18
63 INT264101 Binding of CYP2D6 and Bche 1 0.07 0.33 0.18
64 INT261628 Binding of CHRNA3 and MAOA 1 0.22 1.61 0.17
65 INT224094 Adrbk1 Regulation of Negative_regulation of Adora2a 1 0.06 0 0.17
66 INT101725 Binding of ITGA4 and Chrna7 1 0.00 0 0.16
67 INT147954 Slc5a7 Negative_regulation of Hacu 1 0.06 0 0.16
68 INT70090 TGM1 Positive_regulation of Binding of Ache 1 0.03 0.59 0.15
69 INT340111 Chrna7 Regulation of CYSLTR1 1 0.00 0.25 0.15
70 INT141224 Ache Regulation of Acot1 1 0.09 0.29 0.14
71 INT27393 Tha1 Negative_regulation of Ache 1 0.15 0.24 0.14
72 INT224129 Binding of DRD2 and Adora2a 1 0.03 0.19 0.14
73 INT42772 Penk Negative_regulation of Ache 1 0.06 0 0.14
74 INT210549 Binding of BCHE and Ache 1 0.01 0.82 0.12
75 INT235385 INCENP Negative_regulation of Bche 1 0.01 0.19 0.11
76 INT123101 Binding of APP and Ache 1 0.07 0.32 0.11
77 INT34497 Binding of Oprl1 and Ache 1 0.40 0 0.1
78 INT139558 Chrna4 Regulation of Neurod1 1 0.17 0 0.1
79 INT141223 Bche Regulation of Gene_expression of Acot1 1 0.09 0 0.1
80 INT141225 Bche Regulation of Acot1 1 0.09 0 0.1
81 INT139557 Chrna4 Regulation of Gene_expression of Neurod1 1 0.17 0 0.1
82 INT174104 Binding of HSPG2 and Ache 1 0.16 0.98 0.09
83 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
84 INT262714 ACOT1 Positive_regulation of Negative_regulation of ACHE 1 0.06 1.41 0.08
85 INT261625 Binding of CHRNA3 and CPD 1 0.07 0.35 0.08
86 INT251712 Fig4 Regulation of Ache 1 0.02 0.23 0.08
87 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08
88 INT251703 Fig4 Regulation of Localization of Ache 1 0.07 0.23 0.08
89 INT171709 Rac1 Negative_regulation of Localization of Chrna7 1 0.04 0.75 0.08
90 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07
91 INT275799 Binding of Hcrt and Lynx1 1 0.01 0.34 0.07
92 INT50078 Binding of APOE and NPPA 1 0.30 0.42 0.07
93 INT290158 Binding of Ache and Atp6v1e1 1 0.19 0 0.07
94 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
95 INT220698 Binding of CHRNE and SFTPA1 1 0.01 0.75 0.06
96 INT356110 Binding of App and Slc5a7 1 0.02 0.25 0.05
97 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05
98 INT46677 H2-Q4 Negative_regulation of Bche 1 0.10 0.26 0.05
99 INT323392 SERPINH1 Negative_regulation of BCHE 1 0.02 0.52 0.04
100 INT352062 Binding of SV2A and Chrna7 1 0.00 0.7 0.04
101 INT290181 Binding of APOE and PLTP 1 0.17 1.61 0.04
102 INT330875 PLDN Negative_regulation of Gene_expression of Ache 1 0.01 0.85 0.03
103 INT282799 Chrm2 Positive_regulation of Chrm3 1 0.16 0.29 0.03
104 INT323395 Binding of BCHE and SERPINH1 1 0.02 0.74 0.03
105 INT46678 H2-Q4 Negative_regulation of Ache 1 0.10 0.12 0
106 INT341487 Binding of APOE and TLR2 1 0.00 0.3 0
107 INT307602 Binding of ACHE and LRP5 1 0.01 0.17 0
108 INT186689 Binding of ACHE and Edn1 1 0.28 0 0
109 INT326065 APOE Positive_regulation of LCAT 1 0.53 0.84 0
110 INT190492 Br Regulation of Ache 1 0.30 0.55 0
111 INT209987 Binding of APOE and LDLR 1 0.24 0 0
112 INT90283 Binding of APOE and Il1a 1 0.01 0 0
113 INT201147 Binding of Slc5a7 and Ryr2 1 0.07 0.23 0
114 INT201080 Binding of APOE and HLA-C 1 0.41 0.31 0
115 INT162435 Binding of Igfals and Rapsn 1 0.19 1.34 0
116 INT353802 Binding of APOE and Apob 1 0.05 0.83 0
117 INT354966 Binding of Rapsn and Dlgap1 1 0.01 0.09 0
118 INT330876 PLDN Negative_regulation of Ache 1 0.01 0.45 0
119 INT353801 Binding of APOE and Cd320 1 0.22 0.83 0
120 INT197552 GSTK1 Positive_regulation of NQO1 1 0.09 1.06 0
121 INT250152 Binding of APOE and UBE4B 1 0.21 1.2 0
122 INT326059 APOA1 Positive_regulation of Gene_expression of APOE 1 0.61 0.38 0
123 INT262716 Binding of ACHE and BCHE 1 0.09 0.11 0
124 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0
125 INT326057 APOA1 Regulation of Localization of APOE 1 0.54 1.36 0
126 INT312646 Agrn Positive_regulation of Phosphorylation of CHRNE 1 0.02 0.38 0
127 INT201082 Binding of APOE and HLA-B 1 0.54 1.54 0
128 INT202892 Chrm3 Regulation of Negative_regulation of Camk4 1 0.02 0.37 0
129 INT354969 Binding of Rapsn and Psd 1 0.01 0.09 0
130 INT251702 Fig4 Regulation of Positive_regulation of Ache 1 0.07 0.42 0
131 INT284093 VWF Negative_regulation of APOE 1 0.40 2.32 0
132 INT353803 Binding of APOE and Hdl1 1 0.01 0.83 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for synaptic transmission, cholinergic. They are ordered first by their pain relevance and then by number of times they were reported in synaptic transmission, cholinergic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4
2 INT23330 Binding of Chrna7 79 0.48 10.06 35.5
3 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28
4 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89
5 INT276 Regulation of Ache 83 0.62 16.75 25.99
6 INT3060 Negative_regulation of Bche 94 0.59 46.75 18.51
7 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4
8 INT19071 Localization of Ache 66 0.81 5.1 16.27
9 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73
10 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24
11 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78
12 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75
13 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47
14 INT23675 Negative_regulation of Binding of Chrna7 18 0.37 0.5 10.74
15 INT1252 Binding of Ache 46 0.48 9.94 10.25
16 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51
17 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62
18 INT23209 Binding of Adora2a 17 0.38 2.04 8.35
19 INT54755 Negative_regulation of Adora2a 17 0.58 2.7 7.75
20 INT88079 Gene_expression of Chrna4 20 0.76 8.52 6.98
21 INT539 Negative_regulation of Chrna7 14 0.42 4.59 6.42
22 INT83014 Binding of Adora2a 13 0.48 5.57 5.33
23 INT19072 Regulation of Gene_expression of Ache 14 0.62 2.74 5.29
24 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25
25 INT89664 Negative_regulation of Adora2a 11 0.59 7.81 5.07
26 INT20059 Protein_catabolism of Ache 15 0.98 3.73 4.87
27 INT51468 Regulation of Adora2a 8 0.48 1.5 4.84
28 INT14502 Gene_expression of BCHE 40 0.67 18.52 4.6
29 INT1753 Gene_expression of Ache 38 0.78 15.31 4.58
30 INT11946 Transcription of Ache 18 0.69 2.62 4.13
31 INT3530 Regulation of BCHE 18 0.60 5.47 4.12
32 INT50228 Positive_regulation of Positive_regulation of Adora2a 8 0.39 0.1 4
33 INT4649 Positive_regulation of Chrna7 17 0.50 5.48 3.92
34 INT20455 Positive_regulation of Bche 15 0.59 7.22 3.7
35 INT101701 Regulation of Adora2a 8 0.45 2.3 3.63
36 INT8778 Regulation of Ache 17 0.62 3.7 3.57
37 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52
38 INT28009 Positive_regulation of Gene_expression of Ache 15 0.70 5.46 3.26
39 INT8777 Positive_regulation of Ache 25 0.68 7.77 3.18
40 INT22069 Positive_regulation of Localization of Ache 9 0.70 0.61 2.9
41 INT50080 Binding of APOE 38 0.45 29.61 2.67
42 INT11892 Gene_expression of ACHE 10 0.68 1.32 2.63
43 INT1864 Regulation of Bche 18 0.47 6.18 2.44
44 INT254118 Negative_regulation of Gene_expression of Adora2a 3 0.42 2.54 2.43
45 INT27338 Regulation of ACHE 6 0.62 1.25 2.38
46 INT139556 Positive_regulation of Chrna4 10 0.25 4.52 2.36
47 INT183167 Positive_regulation of Gene_expression of Adora2a 4 0.70 2.37 2.31
48 INT14890 Localization of ACHE 5 0.80 0.47 2.21
49 INT2570 Negative_regulation of Gene_expression of Ache 13 0.43 2.88 2.18
50 INT47543 Positive_regulation of Chrm3 11 0.38 5.23 2.17
51 INT24196 Positive_regulation of Binding of Chrna7 8 0.45 0.79 2.13
52 INT57939 Negative_regulation of Gene_expression of Adora2a 4 0.36 0.15 2.02
53 INT123253 Localization of Chrna4 4 0.44 1.31 1.99
54 INT72785 Positive_regulation of Positive_regulation of Adora2a 2 0.10 1.34 1.96
55 INT194847 Negative_regulation of Positive_regulation of Adora2a 3 0.32 4.52 1.88
56 INT47425 Localization of Chrna7 11 0.81 6.7 1.86
57 INT14503 Binding of BCHE 13 0.48 3.95 1.85
58 INT38201 Negative_regulation of Localization of Ache 8 0.59 2.35 1.82
59 INT8556 Positive_regulation of NQO1 12 0.70 5.11 1.78
60 INT38574 Binding of Ache 9 0.47 3.64 1.74
61 INT8757 Binding of ACHE 10 0.48 5.84 1.72
62 INT2847 Positive_regulation of Negative_regulation of Ache 8 0.49 1.09 1.65
63 INT14891 Positive_regulation of ACHE 10 0.70 5.37 1.64
64 INT169387 Regulation of Gene_expression of Chrna7 4 0.36 2.19 1.63
65 INT96814 Negative_regulation of APOE 13 0.59 10.64 1.61
66 INT44731 Gene_expression of Slc5a7 4 0.76 0.83 1.58
67 INT167847 Positive_regulation of Gene_expression of Chrna7 7 0.49 3.02 1.57
68 INT76496 Localization of Adora2a 3 0.48 0.3 1.54
69 INT19181 Gene_expression of Bche 35 0.68 16.93 1.52
70 INT46028 Negative_regulation of Slc5a7 5 0.38 2.37 1.41
71 INT8476 Binding of Bche 10 0.37 4.38 1.29
72 INT81768 Negative_regulation of Chrna4 5 0.42 1.97 1.2
73 INT37849 Negative_regulation of Negative_regulation of Ache 3 0.43 0.8 1.19
74 INT91595 Regulation of Gene_expression of Adora2a 1 0.52 0 1.19
75 INT29772 Positive_regulation of Positive_regulation of Ache 3 0.50 0.09 1.18
76 INT24197 Regulation of Binding of Chrna7 2 0.11 0 1.14
77 INT27366 Negative_regulation of Negative_regulation of Ache 4 0.43 0.29 1.12
78 INT47027 Positive_regulation of BCHE 6 0.50 2.32 1.09
79 INT155543 Binding of Rapsn 1 0.32 1.7 1.02
80 INT106960 Gene_expression of Chrm3 15 0.69 6.29 0.96
81 INT52090 Transcription of Adora2a 3 0.41 0.33 0.96
82 INT72006 Positive_regulation of Negative_regulation of Adora2a 2 0.40 0.26 0.94
83 INT148401 Regulation of Chrm3 3 0.19 1.19 0.91
84 INT73950 Negative_regulation of Chrm3 1 0.41 0 0.88
85 INT37107 Negative_regulation of CHRNE 4 0.43 2.25 0.87
86 INT37105 Binding of CHRNE 3 0.31 6.88 0.87
87 INT112520 Negative_regulation of Regulation of Ache 2 0.28 1.02 0.87
88 INT19070 Regulation of Localization of Ache 5 0.62 0.39 0.84
89 INT302869 Phosphorylation of Adora2a 1 0.49 0.25 0.78
90 INT302868 Positive_regulation of Phosphorylation of Adora2a 1 0.41 0.25 0.78
91 INT80147 Negative_regulation of Binding of Adora2a 2 0.43 0.15 0.77
92 INT48481 Negative_regulation of Binding of Ache 4 0.36 1.76 0.76
93 INT123254 Regulation of Chrna4 3 0.27 0.84 0.76
94 INT11944 Positive_regulation of Transcription of Ache 3 0.48 1.68 0.75
95 INT46245 Regulation of Binding of Ache 1 0.25 0.06 0.75
96 INT89663 Localization of Adora2a 1 0.74 0.74 0.75
97 INT194852 Protein_catabolism of Adora2a 1 0.56 0.6 0.75
98 INT60826 Negative_regulation of Positive_regulation of Ache 3 0.50 0.68 0.73
99 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72
100 INT270428 Negative_regulation of Binding of APOE 2 0.41 1.16 0.7
101 INT224109 Phosphorylation of Adora2a 1 0.52 0.07 0.69
102 INT336708 Gene_expression of Lynx1 2 0.49 1.72 0.67
103 INT85033 Positive_regulation of Chrna3 2 0.06 0.35 0.67
104 INT123251 Regulation of Gene_expression of Chrna4 2 0.27 0.36 0.67
105 INT133004 Gene_expression of Chrna3 2 0.58 0.63 0.66
106 INT175580 Localization of APOE 10 0.76 18.84 0.65
107 INT149689 Binding of Chrm3 3 0.24 1.54 0.65
108 INT351321 Binding of Lynx1 1 0.01 0.87 0.63
109 INT159717 Gene_expression of Slc5a7 5 0.63 0.81 0.62
110 INT134951 Gene_expression of NQO1 14 0.78 7.87 0.61
111 INT215637 Regulation of Regulation of Adora2a 1 0.14 0.16 0.61
112 INT99329 Binding of Chrna4 3 0.37 0.45 0.6
113 INT310648 Negative_regulation of Negative_regulation of BCHE 2 0.27 1.79 0.59
114 INT135044 Regulation of Gene_expression of Ache 2 0.31 0.85 0.58
115 INT123256 Regulation of Localization of Chrna4 1 0.27 0.28 0.58
116 INT141458 Regulation of Gene_expression of Adora2a 2 0.45 0.67 0.57
117 INT104335 Localization of Chrm3 2 0.62 0.58 0.57
118 INT215639 Positive_regulation of Binding of Adora2a 1 0.24 0.24 0.55
119 INT144394 Protein_catabolism of ACHE 1 0.89 0.24 0.53
120 INT224106 Regulation of Negative_regulation of Adora2a 1 0.17 0.26 0.51
121 INT4387 Phosphorylation of Ache 3 0.79 1.15 0.5
122 INT104336 Positive_regulation of Localization of Chrm3 1 0.38 0.14 0.5
123 INT224107 Negative_regulation of Negative_regulation of Adora2a 1 0.28 0.32 0.48
124 INT79516 Positive_regulation of Gene_expression of Bche 3 0.50 1 0.47
125 INT119609 Regulation of CHRNE 1 0.05 0.36 0.46
126 INT323400 Localization of BCHE 1 0.66 1.87 0.46
127 INT72143 Regulation of Binding of Adora2a 1 0.17 0 0.45
128 INT96816 Regulation of APOE 8 0.45 6.62 0.44
129 INT68850 Negative_regulation of NQO1 2 0.19 0.19 0.43
130 INT39873 Negative_regulation of Gene_expression of Ache 2 0.59 1.56 0.43
131 INT86052 Regulation of Transcription of Ache 1 0.12 0 0.41
132 INT281775 Regulation of Positive_regulation of Chrna4 1 0.02 0.98 0.41
133 INT86053 Positive_regulation of Binding of Ache 2 0.43 0 0.4
134 INT102385 Regulation of Transcription of Adora2a 1 0.21 0.09 0.4
135 INT94218 Positive_regulation of Regulation of Ache 2 0.40 0 0.38
136 INT102387 Negative_regulation of Transcription of Adora2a 1 0.09 0.24 0.37
137 INT169388 Transcription of Chrna7 2 0.69 0.27 0.36
138 INT8776 Negative_regulation of Positive_regulation of Ache 2 0.43 1.17 0.36
139 INT45360 Negative_regulation of Binding of Bche 1 0.37 0.27 0.36
140 INT169386 Regulation of Transcription of Chrna7 1 0.45 0.05 0.36
141 INT336711 Negative_regulation of Lynx1 1 0.35 0.94 0.36
142 INT167696 Positive_regulation of Gene_expression of NQO1 3 0.45 1.22 0.35
143 INT271775 Positive_regulation of Gene_expression of Ache 3 0.69 5.16 0.34
144 INT47026 Positive_regulation of Gene_expression of BCHE 1 0.44 0.23 0.34
145 INT131542 Negative_regulation of Gene_expression of APOE 6 0.40 3.92 0.33
146 INT68851 Localization of NQO1 2 0.62 0.05 0.33
147 INT201347 Negative_regulation of Gene_expression of Chrm3 4 0.30 2.48 0.31
148 INT96815 Regulation of Gene_expression of APOE 2 0.62 1.1 0.29
149 INT221765 Positive_regulation of Gene_expression of Adora2a 2 0.49 0.2 0.27
150 INT224108 Positive_regulation of Localization of Adora2a 1 0.32 0.14 0.27
151 INT224114 Regulation of Localization of Adora2a 1 0.29 0.14 0.27
152 INT220699 Positive_regulation of CHRNE 5 0.32 2.26 0.26
153 INT255780 Negative_regulation of Negative_regulation of ACHE 2 0.43 1.28 0.24
154 INT201157 Positive_regulation of Slc5a7 1 0.19 2.94 0.24
155 INT48022 Protein_catabolism of BCHE 1 0.87 0 0.24
156 INT334903 Positive_regulation of Localization of Chrna7 2 0.04 0.83 0.23
157 INT162933 Phosphorylation of NQO1 1 0.69 0.5 0.23
158 INT174101 Protein_catabolism of Ache 3 0.66 2.45 0.22
159 INT224117 Negative_regulation of Positive_regulation of Adora2a 1 0.27 0.11 0.22
160 INT224105 Regulation of Phosphorylation of Adora2a 1 0.17 0 0.21
161 INT193810 Phosphorylation of APOE 2 0.27 1.13 0.2
162 INT353827 Protein_catabolism of Bche 1 0.05 0 0.2
163 INT538 Protein_catabolism of Chrna7 2 0.57 1.01 0.19
164 INT1255 Regulation of Binding of Ache 1 0.02 0 0.19
165 INT95662 Binding of Chrna3 1 0.00 0.17 0.17
166 INT35620 Positive_regulation of Negative_regulation of ACHE 1 0.48 0 0.17
167 INT147953 Positive_regulation of Positive_regulation of Ache 2 0.46 0.08 0.16
168 INT224115 Positive_regulation of Phosphorylation of Adora2a 1 0.32 0 0.16
169 INT224103 Negative_regulation of Phosphorylation of Adora2a 1 0.27 0 0.16
170 INT96772 Positive_regulation of Gene_expression of APOE 5 0.66 5.44 0.14
171 INT251700 Positive_regulation of Protein_catabolism of Ache 1 0.46 0.44 0.14
172 INT261639 Positive_regulation of CHRNA3 1 0.38 0.68 0.14
173 INT25479 Regulation of Slc5a7 2 0.17 0.85 0.13
174 INT7652 Localization of Ache 2 0.80 0 0.13
175 INT37103 Gene_expression of CHRNE 5 0.67 4.32 0.12
176 INT1796 Phosphorylation of Chrna7 1 0.82 0 0.12
177 INT52420 Negative_regulation of Protein_catabolism of Ache 1 0.04 0.44 0.12
178 INT270427 Negative_regulation of Binding of ACHE 2 0.42 1.82 0.11
179 INT43207 Regulation of Positive_regulation of Chrna7 1 0.01 0 0.11
180 INT326081 Negative_regulation of Localization of APOE 1 0.56 2.23 0.11
181 INT52411 Regulation of Negative_regulation of Bche 3 0.20 1.47 0.1
182 INT139554 Positive_regulation of Gene_expression of Chrna4 2 0.25 0 0.1
183 INT46027 Negative_regulation of Negative_regulation of Slc5a7 1 0.38 0 0.1
184 INT139553 Transcription of Chrna4 1 0.27 0 0.1
185 INT139555 Positive_regulation of Positive_regulation of Chrna4 1 0.25 0 0.1
186 INT261646 Localization of CHRNA3 1 0.65 0.91 0.09
187 INT300643 Positive_regulation of Binding of APOE 1 0.44 0.8 0.09
188 INT44609 Negative_regulation of Positive_regulation of APOE 1 0.16 0.9 0.09
189 INT4388 Negative_regulation of Phosphorylation of Ache 1 0.37 0.07 0.09
190 INT220702 Protein_catabolism of CHRNE 1 0.64 1.22 0.08
191 INT186574 Negative_regulation of Gene_expression of ACHE 1 0.37 0.51 0.08
192 INT281418 Regulation of Negative_regulation of Ache 2 0.43 1.15 0.07
193 INT241728 Regulation of Transcription of Adora2a 1 0.42 0.27 0.07
194 INT205147 Regulation of Phosphorylation of APOE 1 0.06 0.34 0.07
195 INT63966 Negative_regulation of Gene_expression of BCHE 1 0.43 0 0.07
196 INT241725 Transcription of Adora2a 1 0.67 0.27 0.07
197 INT201153 Localization of Slc5a7 1 0.20 0.75 0.06
198 INT271774 Regulation of Positive_regulation of Ache 1 0.27 0 0.06
199 INT313475 Regulation of NQO1 1 0.04 0.42 0.05
200 INT210526 Phosphorylation of Ache 1 0.21 0.29 0.05
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