GO:0007275

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Name multicellular organismal development
Categary Process
Go Slim No
Go Link GO:0007275
Unique Molecular Interactions 6513
Total Molecular Interactions 9397
Total Single Events 71062
Pain Genes Associated 609

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for multicellular organismal development. They are ordered first by their pain relevance and then by number of times they were reported for multicellular organismal development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69872 Binding of MC1R and POMC 52 0.54 8.87 18.3
2 INT2161 Gnrh1 Positive_regulation of Localization of LH 33 0.73 0.87 14.34
3 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
4 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
5 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
6 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
7 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
8 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
9 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
10 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
11 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
12 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
13 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
14 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
15 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
16 INT113223 POMC Regulation of MC1R 6 0.68 0.39 4.24
17 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
18 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
19 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
20 INT104977 MITF Regulation of Gene_expression of MC1R 1 0.69 0.91 3.71
21 INT64883 Ptger2 Positive_regulation of Ina 1 0.03 1.26 3.64
22 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 0.00 1.25 3.63
23 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
24 INT29837 Gnrh1 Positive_regulation of LH 6 0.67 0 3.53
25 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
26 INT334928 Binding of pr and Aes 1 0.00 1.49 3.38
27 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
28 INT69823 Binding of GHR and RYBP 1 0.01 0 3.23
29 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
30 INT289979 Binding of Helt and Negative_regulation of Maoa 1 0.00 0.17 3.14
31 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
32 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
33 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
34 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
35 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
36 INT107723 POMC Positive_regulation of MC1R 7 0.68 0.71 2.82
37 INT229497 Binding of Vim and Ndel1 1 0.33 3.5 2.81
38 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
39 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
40 INT87267 Binding of BMP8B and KRIT1 1 0.06 0.16 2.69
41 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
42 INT91350 Binding of Pla2g4a and RYBP 1 0.00 1.15 2.65
43 INT150457 Binding of Sort1 and Prss12 3 0.21 1.36 2.64
44 INT212505 Binding of pr and Lbp 1 0.01 4.26 2.62
45 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
46 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
47 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
48 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
49 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
50 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
51 INT170038 Gtf3a Regulation of Gene_expression of DRGX 1 0.00 1.36 2.46
52 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46
53 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
54 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
55 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37
56 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
57 INT153728 RYBP Positive_regulation of Gpt 3 0.03 2.01 2.36
58 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
59 INT284860 Binding of Pdzd2 and Nav1 9 0.29 2.33 2.34
60 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
61 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 0.00 0.08 2.31
62 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
63 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
64 INT128778 Binding of Mcam and Nav1 1 0.03 0.51 2.28
65 INT128777 Binding of Cntn1 and Nav1 1 0.48 0.51 2.28
66 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
67 INT40408 Positive_regulation of Gnrh1 Positive_regulation of LH 2 0.58 0 2.21
68 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
69 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
70 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
71 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
72 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
73 INT344386 Efnb1 Positive_regulation of Phosphorylation of Ephb2 1 0.15 2.85 2.13
74 INT273120 NOVA2 Regulation of Gene_expression of MET 1 0.23 1.17 2.11
75 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
76 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
77 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
78 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
79 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
80 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
81 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
82 INT334532 Sema3a Negative_regulation of Gene_expression of Nrp1 1 0.19 7.58 2
83 INT274372 Phc1 Negative_regulation of Slc6a3 1 0.06 0.47 1.99
84 INT213973 Binding of Pax3 and Mthfd1 1 0.00 0.16 1.99
85 INT53751 Positive_regulation of Cyp2e1 Positive_regulation of RYBP 1 0.14 0.89 1.98
86 INT34662 Abat Positive_regulation of Localization of Gnrh1 1 0.26 0 1.98
87 INT110525 Binding of MC1R and OCA2 1 0.41 1.08 1.97
88 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
89 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
90 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
91 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
92 INT113572 Binding of DMRT1 and OPRM1 1 0.01 0 1.9
93 INT203044 Binding of PDCD1 and DTHD1 1 0.02 3.19 1.87
94 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
95 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
96 INT9786 Gnrh1 Regulation of LH 7 0.40 0.58 1.82
97 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
98 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
99 INT305741 Binding of Kcnk2 and Sort1 1 0.54 1.01 1.8
100 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
101 INT150456 Binding of Sort1 and Nts 3 0.45 0.64 1.79
102 INT334345 Binding of GRP and Helt 1 0.02 0 1.79
103 INT142073 Binding of Helt and Nrm 1 0.00 0 1.74
104 INT129953 Oprd1 Regulation of Cspg5 1 0.17 0.15 1.74
105 INT57249 GNRH1 Regulation of Regulation of CGA 1 0.20 0 1.74
106 INT92369 Binding of CYP2D6 and RYBP 1 0.25 0.15 1.73
107 INT27788 Gnrh1 Positive_regulation of Positive_regulation of LH 3 0.55 0.17 1.72
108 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
109 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
110 INT119413 SEMA6A Positive_regulation of TNFRSF11A 1 0.10 2.48 1.7
111 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
112 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
113 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
114 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
115 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
116 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
117 INT151889 Binding of Adarb1 and DLL1 1 0.00 0 1.66
118 INT347396 RYBP Positive_regulation of Binding of Sdcbp 1 0.00 0.92 1.66
119 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
120 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
121 INT317184 BMS1 Regulation of Gene_expression of NAV1 1 0.03 1.94 1.62
122 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
123 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
124 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
125 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
126 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
127 INT48790 Negative_regulation of Rtcd1 Negative_regulation of Pax3 1 0.02 0 1.59
128 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
129 INT81709 POMC Regulation of Gene_expression of ITGB2 1 0.40 0.34 1.57
130 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56
131 INT81715 POMC Regulation of ITGB2 1 0.40 0.34 1.55
132 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
133 INT333150 Tlx2 Regulation of asa 1 0.04 2.17 1.55
134 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
135 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
136 INT100784 RYBP Positive_regulation of CYP3A4 1 0.44 0 1.54
137 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53
138 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
139 INT145072 ASIP Negative_regulation of MC1R 1 0.29 0 1.52
140 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
141 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
142 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
143 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5
144 INT93781 Racgap1 Positive_regulation of Positive_regulation of Gnptab 1 0.02 0.07 1.49
145 INT93782 Racgap1 Positive_regulation of Rgs9 1 0.55 0.07 1.49
146 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
147 INT93783 Racgap1 Positive_regulation of Gnptab 1 0.02 0.07 1.49
148 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
149 INT334633 Binding of Cntnap1 and Nav1 1 0.10 1.36 1.48
150 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
151 INT276687 Pax3 Positive_regulation of Nkx1-1 1 0.00 0.59 1.47
152 INT144452 Binding of GPM6A and GPM6B 1 0.28 0 1.46
153 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
154 INT104975 MITF Regulation of Transcription of PRSS1 1 0.68 0.35 1.46
155 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
156 INT104972 MITF Regulation of Transcription of TYR 1 0.20 0.35 1.45
157 INT6976 Helt Regulation of Gene_expression of St8sia1 1 0.00 0.07 1.45
158 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
159 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
160 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
161 INT139768 Binding of TRPV1 and ICK 1 0.41 1.59 1.42
162 INT139767 ICK Regulation of TRPV1 1 0.30 1.59 1.42
163 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42
164 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
165 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42
166 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
167 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
168 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4
169 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
170 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
171 INT161189 CRX Regulation of Gene_expression of Rvm 1 0.00 2 1.39
172 INT161191 CRX Regulation of Gene_expression of Trib3 1 0.00 2 1.38
173 INT131949 ANTXR1 Positive_regulation of NAV1 1 0.03 0.23 1.38
174 INT87266 Negative_regulation of Binding of BMP8B and KRIT1 1 0.05 0.07 1.37
175 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
176 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
177 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
178 INT229496 Binding of Ndel1 and Gopc 1 0.08 2.05 1.36
179 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
180 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
181 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
182 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
183 INT19633 GNRH1 Regulation of Localization of CGA 4 0.44 0.82 1.33
184 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
185 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33
186 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
187 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
188 INT130786 Positive_regulation of Oprm1 Positive_regulation of Arc 1 0.27 0.9 1.31
189 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3
190 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
191 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
192 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29
193 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
194 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
195 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
196 INT121802 DEAF1 Negative_regulation of HTR1A 1 0.46 0.88 1.29
197 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
198 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
199 INT136644 T(1;9)27H Negative_regulation of Gene_expression of Hand1 1 0.15 1.14 1.27
200 INT71109 Binding of INSRR and MC1R 1 0.01 0 1.27

Single Events

The table below shows the top 100 pain related interactions that have been reported for multicellular organismal development. They are ordered first by their pain relevance and then by number of times they were reported in multicellular organismal development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT439 Localization of Gnrh1 976 0.81 100.96 363.25
3 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
5 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75
6 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
7 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46
8 INT6852 Localization of TNF 883 0.81 705.95 270.84
9 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
10 INT6481 Binding of TNF 624 0.48 510.2 214.82
11 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
12 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
13 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
14 INT9660 Regulation of TNF 363 0.62 312.94 139.99
15 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
16 INT7395 Localization of GNRH1 399 0.81 62.88 117.68
17 INT2159 Regulation of Localization of Gnrh1 200 0.62 13.28 99.07
18 INT56130 Gene_expression of MC1R 259 0.78 62.7 97.55
19 INT2122 Negative_regulation of Localization of Gnrh1 226 0.59 26.92 92.04
20 INT10166 Localization of Tnf 237 0.81 153.95 88.64
21 INT22967 Positive_regulation of RYBP 94 0.56 37.04 85.92
22 INT4289 Positive_regulation of Localization of Gnrh1 202 0.70 12.3 84.01
23 INT8534 Localization of Pax3 85 0.59 28.71 82.82
24 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
25 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
26 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26
27 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
28 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
29 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
30 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47
31 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97
32 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
33 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63
34 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
35 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32
36 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
37 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
38 INT18883 Negative_regulation of RYBP 53 0.56 21.14 57.52
39 INT129303 Positive_regulation of NAV1 54 0.70 36.92 57.45
40 INT21737 Binding of MC1R 129 0.48 45.45 56.54
41 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
42 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53
43 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
44 INT61873 Gene_expression of Arc 128 0.78 128.25 52.24
45 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
46 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
47 INT2197 Gene_expression of Gnrh1 184 0.78 40.04 50.57
48 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
49 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33
50 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
51 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
52 INT111051 Negative_regulation of Nav1 64 0.59 25.51 47.27
53 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
54 INT4656 Localization of RYBP 49 0.77 5.28 46.21
55 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
56 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
57 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68
58 INT4913 Binding of Pax3 52 0.28 9.57 42.67
59 INT11180 Binding of RYBP 52 0.46 13.86 42.53
60 INT13354 Transcription of TNF 108 0.72 85.81 42.32
61 INT5130 Regulation of GNRH1 139 0.62 31.95 42.08
62 INT60388 Gene_expression of Helt 90 0.07 19.18 41.72
63 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
64 INT103261 Positive_regulation of Nav1 68 0.70 24.25 39.27
65 INT16323 Gene_expression of pr 62 0.66 36.14 38.26
66 INT116321 Regulation of Nav1 38 0.62 26.62 37.97
67 INT18774 Gene_expression of RYBP 67 0.65 47.66 37.59
68 INT131413 Positive_regulation of Gene_expression of NAV1 35 0.70 17.5 36.83
69 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
70 INT70437 Negative_regulation of Mdk 115 0.57 41.03 35.72
71 INT111052 Positive_regulation of Gene_expression of Nav1 44 0.70 18.98 35.28
72 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
73 INT103262 Localization of Nav1 53 0.81 19.23 34.44
74 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66
75 INT5868 Positive_regulation of GNRH1 122 0.69 20.96 32.8
76 INT14823 Gene_expression of MET 103 0.75 51.92 32.48
77 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
78 INT35406 Localization of Tnf 94 0.81 64.63 31.65
79 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
80 INT7396 Regulation of Localization of GNRH1 81 0.62 6.57 31.31
81 INT10285 Binding of ADRA1D 102 0.47 25.82 31.11
82 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
83 INT7397 Negative_regulation of Localization of GNRH1 86 0.59 15.45 29.78
84 INT11796 Positive_regulation of Helt 52 0.31 11.7 29.22
85 INT5440 Negative_regulation of Ina 85 0.58 10.52 28.98
86 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
87 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8
88 INT4459 Positive_regulation of Arc 74 0.69 33.61 28.29
89 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97
90 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
91 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71
92 INT62169 Positive_regulation of MC1R 72 0.69 14.56 27.52
93 INT73314 Gene_expression of Arc 133 0.78 67.78 27.44
94 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
95 INT123419 Binding of NAV1 37 0.48 7.09 26.43
96 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
97 INT136268 Localization of NAV1 22 0.75 2.84 26.23
98 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
99 INT28336 Positive_regulation of Pax3 37 0.33 20.94 25.66
100 INT116226 Regulation of NAV1 20 0.51 14.32 25.61
101 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
102 INT7394 Positive_regulation of Localization of GNRH1 67 0.69 7.22 25.29
103 INT64185 Gene_expression of TNFRSF11A 131 0.76 75.15 24.73
104 INT256285 Gene_expression of Efnb1 32 0.70 36.25 24.73
105 INT10929 Positive_regulation of FLII 46 0.67 13.17 24.63
106 INT10240 Gene_expression of Gap43 58 0.78 22.11 24.45
107 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
108 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
109 INT5131 Gene_expression of GNRH1 109 0.78 28.79 23.94
110 INT18884 Regulation of RYBP 25 0.38 11.43 23.2
111 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
112 INT825 Negative_regulation of ADRA1D 54 0.58 20.25 22.78
113 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
114 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24
115 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
116 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
117 INT168482 Gene_expression of Nnat 45 0.77 24.01 21.53
118 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
119 INT95167 Positive_regulation of DRGX 33 0.22 26.72 21.04
120 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87
121 INT99237 Gene_expression of Ntrk3 84 0.77 38.68 20.77
122 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75
123 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
124 INT6699 Positive_regulation of ADRA1D 65 0.70 22.72 20.31
125 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
126 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
127 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
128 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59
129 INT106097 Localization of pr 20 0.62 12.01 19.46
130 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
131 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
132 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29
133 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
134 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
135 INT13244 Binding of Helt 30 0.31 4.56 18.01
136 INT171060 Gene_expression of PDX1 72 0.75 72.57 17.97
137 INT10555 Gene_expression of FLII 37 0.75 7.81 17.6
138 INT70557 Negative_regulation of Localization of Pax3 1 0.36 1.15 17.32
139 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29
140 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23
141 INT111050 Negative_regulation of Gene_expression of Nav1 23 0.58 5.97 17.06
142 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
143 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96
144 INT84712 Regulation of MC1R 36 0.62 9.34 16.91
145 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
146 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
147 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
148 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
149 INT256282 Gene_expression of Efnb2 3 0.76 17.61 16.41
150 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34
151 INT104045 Regulation of Hand1 65 0.35 51.32 16.26
152 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24
153 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
154 INT113384 Regulation of Gene_expression of Nav1 20 0.62 8.57 16.15
155 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
156 INT114507 Negative_regulation of Gene_expression of NAV1 17 0.43 7.24 15.93
157 INT98647 Positive_regulation of Mdk 65 0.59 32.93 15.67
158 INT20966 Positive_regulation of Arc 30 0.70 24.38 15.62
159 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
160 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
161 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46
162 INT112207 Binding of Nav1 27 0.47 7.1 15.43
163 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
164 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
165 INT6163 Negative_regulation of INA 39 0.43 2.9 14.8
166 INT11795 Negative_regulation of Helt 33 0.28 6.51 14.76
167 INT7523 Regulation of ADRA1D 42 0.45 11.63 14.52
168 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
169 INT10173 Binding of Tnf 45 0.48 35.6 14.32
170 INT8089 Binding of Gnrh1 47 0.48 10.04 13.99
171 INT13118 Positive_regulation of Ina 48 0.69 7.39 13.85
172 INT11996 Gene_expression of Ina 34 0.67 4.8 13.82
173 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
174 INT50056 Positive_regulation of Dll1 13 0.67 3.16 13.7
175 INT173505 Localization of Hand2 63 0.57 45.32 13.66
176 INT18882 Negative_regulation of Localization of RYBP 11 0.49 1.15 13.51
177 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
178 INT13572 Localization of Helt 31 0.36 5.85 13.41
179 INT20066 Gene_expression of Mdk 38 0.76 21.41 13.4
180 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32
181 INT20378 Localization of Hand1 53 0.71 41.96 13.31
182 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
183 INT344368 Positive_regulation of Gene_expression of Efnb1 13 0.63 18.39 13.31
184 INT12464 Binding of MET 38 0.47 10.3 13.15
185 INT65172 Negative_regulation of Ntrk2 35 0.59 9.89 13.08
186 INT121783 Positive_regulation of Gene_expression of Arc 30 0.70 29.22 13.02
187 INT35097 Gene_expression of Cux1 6 0.58 3.86 12.83
188 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
189 INT12156 Positive_regulation of MET 43 0.67 17.75 12.64
190 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
191 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
192 INT94464 Negative_regulation of Hand1 44 0.41 31.5 12.39
193 INT7234 Binding of GNRH1 43 0.47 21.59 12.36
194 INT166114 Gene_expression of Dmbx1 36 0.74 29.64 12.28
195 INT56883 Positive_regulation of Dll1 8 0.49 3.49 12.25
196 INT21987 Positive_regulation of Rorb 30 0.33 12.7 12.24
197 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23
198 INT7611 Positive_regulation of Cspg5 17 0.67 2.97 12.2
199 INT137043 Transcription of NAV1 16 0.72 6.98 12.12
200 INT70556 Positive_regulation of Localization of Pax3 9 0.34 3.13 12.11
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