GO:0007276

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Name gamete generation
Categary Process
Go Slim No
Go Link GO:0007276
Unique Molecular Interactions 27
Total Molecular Interactions 33
Total Single Events 221
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for gamete generation. They are ordered first by their pain relevance and then by number of times they were reported for gamete generation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT280949 Binding of Fst and Inhbe 3 0.01 2.51 1.15
2 INT167819 IFNA1 Positive_regulation of Fst 1 0.39 0 1.07
3 INT146897 Binding of Fst and OR13H1 1 0.01 0 1.05
4 INT137102 Fst Regulation of Sec22b 1 0.07 0 0.67
5 INT137101 Fst Regulation of Htr1a 1 0.24 0 0.67
6 INT144320 Binding of Fst and Rbm39 1 0.04 0 0.59
7 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57
8 INT129270 Binding of Wnt4 and Efs 1 0.00 0 0.55
9 INT121378 Fancl Positive_regulation of MIF 1 0.01 0.92 0.42
10 INT296304 Binding of SPIN1 and ENDO1 1 0.03 1.7 0.37
11 INT296306 Binding of BGLAP and SPIN1 1 0.05 1.69 0.37
12 INT212568 Fst Regulation of Gene_expression of Il2 1 0.30 0.07 0.24
13 INT311905 Binding of Runx2 and Smad1 1 0.12 0.46 0.13
14 INT311912 Gene_expression of Smad1 Positive_regulation of Gene_expression of Mmp13 1 0.08 0.51 0.12
15 INT222511 Il1a Positive_regulation of Gene_expression of Fst 1 0.01 0.32 0.08
16 INT222431 Tlr4 Positive_regulation of Gene_expression of Fst 1 0.01 0.29 0.06
17 INT311910 Acvrl1 Positive_regulation of Phosphorylation of Smad1 1 0.12 0.24 0.06
18 INT222463 Inhba Positive_regulation of Gene_expression of Fst 1 0.01 0 0.05
19 INT222520 Mzb1 Positive_regulation of Gene_expression of Fst 1 0.04 0 0.05
20 INT222476 Gnrh1 Negative_regulation of Gene_expression of Fst 1 0.04 0 0.05
21 INT311904 Smad2 Positive_regulation of Gene_expression of Smad1 1 0.13 0.44 0.03
22 INT340558 Gene_expression of Fst Positive_regulation of Akt1 1 0.09 0.41 0.03
23 INT354896 Binding of Psen2 and Fancd2 1 0.04 0.75 0.03
24 INT319219 Bmpr2 Positive_regulation of Smad1 1 0.18 0.29 0.03
25 INT319217 Bmpr2 Positive_regulation of Gene_expression of Smad1 1 0.19 0.11 0.03
26 INT329746 ENG Positive_regulation of SMAD1 1 0.15 0.44 0
27 INT295572 Binding of Fst and Mstn 1 0.13 0.38 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for gamete generation. They are ordered first by their pain relevance and then by number of times they were reported in gamete generation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65277 Negative_regulation of Fst 20 0.43 4.61 11.83
2 INT70572 Gene_expression of Fst 33 0.78 5.22 8.24
3 INT60931 Negative_regulation of Fst 15 0.57 5.44 7.21
4 INT86060 Positive_regulation of Fst 13 0.64 3.04 6.33
5 INT65276 Gene_expression of Fst 12 0.65 4.99 5.05
6 INT33237 Regulation of Fst 10 0.39 1.3 3
7 INT163580 Positive_regulation of Fst 4 0.19 2.85 2.17
8 INT138316 Regulation of Fst 5 0.44 1.15 1.99
9 INT280933 Binding of Fst 4 0.12 3.53 1.63
10 INT296307 Positive_regulation of SPIN1 1 0.11 7.1 1.15
11 INT280942 Localization of Fst 2 0.22 2.13 0.91
12 INT296308 Localization of SPIN1 1 0.12 4.69 0.89
13 INT237413 Binding of Fancd2 3 0.09 1.75 0.88
14 INT220605 Positive_regulation of Fancd2 2 0.09 0.1 0.8
15 INT237405 Positive_regulation of Binding of Fancd2 1 0.09 0 0.8
16 INT296309 Binding of SPIN1 1 0.06 3.54 0.72
17 INT156967 Localization of Fst 2 0.66 0.1 0.66
18 INT156968 Negative_regulation of Localization of Fst 1 0.37 0.1 0.64
19 INT349703 Positive_regulation of Transcription of Fst 1 0.46 0.14 0.53
20 INT349725 Transcription of Fst 1 0.63 0.13 0.53
21 INT285501 Gene_expression of Smad1 6 0.42 3.09 0.41
22 INT311882 Negative_regulation of Smad1 1 0.25 0.99 0.39
23 INT117096 Gene_expression of Wnt4 2 0.67 4.68 0.38
24 INT317694 Negative_regulation of Localization of Fst 1 0.12 0.79 0.36
25 INT288541 Negative_regulation of Gene_expression of Fst 2 0.23 1.18 0.34
26 INT349714 Binding of Fst 1 0.34 0.19 0.32
27 INT311891 Phosphorylation of Smad1 4 0.51 1.34 0.18
28 INT222654 Regulation of Gene_expression of Fst 1 0.09 0 0.15
29 INT310174 Positive_regulation of Smad1 9 0.45 2.16 0.14
30 INT220601 Gene_expression of Fancd2 5 0.04 1.38 0.07
31 INT222593 Negative_regulation of Gene_expression of Fst 1 0.07 0 0.05
32 INT311890 Binding of Smad1 2 0.23 0.46 0.04
33 INT340535 Positive_regulation of Gene_expression of Fst 1 0.26 0.4 0.03
34 INT340540 Regulation of Gene_expression of Fst 1 0.17 0.42 0.03
35 INT354895 Regulation of Binding of Fancd2 1 0.06 0.8 0.03
36 INT311888 Negative_regulation of Phosphorylation of Smad1 1 0.25 0.48 0.03
37 INT222613 Positive_regulation of Gene_expression of Fst 4 0.42 0.25 0
38 INT220591 Positive_regulation of Gene_expression of Fancd2 2 0.03 1.06 0
39 INT329771 Positive_regulation of SMAD1 1 0.36 2.3 0
40 INT329780 Negative_regulation of Positive_regulation of SMAD1 1 0.22 0.51 0
41 INT205585 Regulation of Wnt4 1 0.45 0.7 0
42 INT205578 Negative_regulation of Wnt4 1 0.43 1.69 0
43 INT205581 Regulation of Negative_regulation of Wnt4 1 0.27 0.7 0
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