GO:0007292

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Name female gamete generation
Categary Process
Go Slim No
Go Link GO:0007292
Unique Molecular Interactions 81
Total Molecular Interactions 111
Total Single Events 1138
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for female gamete generation. They are ordered first by their pain relevance and then by number of times they were reported for female gamete generation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT25026 PLOD1 Regulation of FSHR 4 0.19 0.38 1.15
2 INT108546 BCL2L10 Regulation of MAPKAPK5 1 0.03 1.22 1.1
3 INT35159 FSHR Regulation of PRL 2 0.34 0 0.6
4 INT60537 Gnrh1 Positive_regulation of Localization of FSHR 1 0.00 0.19 0.6
5 INT28119 Atm Negative_regulation of Cck 1 0.42 0 0.56
6 INT54584 GNRH1 Positive_regulation of FSHR 3 0.48 2.02 0.54
7 INT23486 HBE1 Positive_regulation of Localization of FSHB 1 0.03 0 0.54
8 INT160779 Cps1 Positive_regulation of ATM 1 0.01 0.94 0.53
9 INT23483 HBE1 Positive_regulation of FSHB 1 0.01 0 0.53
10 INT48114 GHRH Positive_regulation of Localization of CGB 1 0.05 0 0.48
11 INT39178 NPL Regulation of FSHR 1 0.03 0 0.46
12 INT32662 Hps1 Negative_regulation of Localization of CGB 1 0.00 0 0.46
13 INT25027 CRH Negative_regulation of Negative_regulation of FSHR 1 0.25 0 0.42
14 INT48115 GH1 Positive_regulation of CGB 1 0.06 0 0.38
15 INT12522 Binding of FSHR and POMC 1 0.33 3.89 0.34
16 INT31044 Gnrh1 Negative_regulation of Localization of FSHR 1 0.04 0 0.32
17 INT31040 Ghrh Positive_regulation of Localization of FSHR 1 0.05 0 0.31
18 INT31041 Ghrh Positive_regulation of FSHR 1 0.05 0 0.31
19 INT35080 CRH Negative_regulation of Localization of FSHR 1 0.03 0 0.29
20 INT44441 GNRH1 Positive_regulation of Localization of FSHR 2 0.15 0.86 0.26
21 INT35162 GH1 Regulation of FSHR 1 0.17 0 0.21
22 INT35161 FSHR Regulation of LHB 1 0.18 0 0.21
23 INT35153 FSHR Regulation of GHRH 1 0.04 0 0.21
24 INT35156 FSHR Regulation of PGR 1 0.18 0 0.21
25 INT68510 Binding of ATM and PRLR 1 0.01 0 0.19
26 INT25052 Crh Regulation of FSHR 1 0.08 0 0.19
27 INT179158 ATM Regulation of Gene_expression of GOPC 1 0.01 0 0.18
28 INT179163 ATM Regulation of Gene_expression of IL13 1 0.01 0 0.18
29 INT179161 ATM Regulation of Gene_expression of IL6 1 0.02 0 0.18
30 INT179162 ATM Regulation of Gene_expression of IL8 1 0.01 0 0.18
31 INT214691 Binding of CGA and CGB 1 0.01 0.7 0.17
32 INT25054 Crh Negative_regulation of FSHR 1 0.07 0 0.17
33 INT65677 Binding of CGA and FSHR 2 0.25 0.29 0.16
34 INT26541 CGB Regulation of Gene_expression of Penk 1 0.03 0 0.15
35 INT284891 FSHR Positive_regulation of Gene_expression of PLOD1 2 0.03 1.32 0.11
36 INT147936 CGA Regulation of Gene_expression of FSHR 1 0.31 0.71 0.1
37 INT12523 Binding of FSHR and LHB 1 0.11 0.98 0.09
38 INT12520 Binding of FSHR and GANAB 1 0.03 0.97 0.09
39 INT334918 GNRH1 Positive_regulation of Gene_expression of FSHR 2 0.11 1.27 0.03
40 INT350114 Positive_regulation of GNRH1 Positive_regulation of FSHR 1 0.05 0.86 0.03
41 INT207817 Negative_regulation of Parp1 Positive_regulation of Atm 1 0.53 0.2 0
42 INT187677 Negative_regulation of FSHR Positive_regulation of DBT 1 0.03 0 0
43 INT350120 FSHR Regulation of CYP19A1 1 0.01 3.02 0
44 INT207815 Parp1 Negative_regulation of Phosphorylation of Atm 1 0.42 0.15 0
45 INT207816 Parp1 Regulation of Positive_regulation of Atm 1 0.51 0.21 0
46 INT333456 ATM Positive_regulation of CHEK2 1 0.20 0 0
47 INT350117 GNRHR Negative_regulation of Localization of FSHR 1 0.01 1.06 0
48 INT333446 ATM Positive_regulation of CHEK1 1 0.20 0 0
49 INT333455 ATM Positive_regulation of TP53 1 0.18 0 0
50 INT151093 BCL2L10 Regulation of Gene_expression of TRPM8 1 0.20 0 0
51 INT333451 ATM Positive_regulation of Negative_regulation of CHEK1 1 0.14 0 0
52 INT187674 FSHR Positive_regulation of Gene_expression of CYP19A1 1 0.24 0 0
53 INT25051 Crh Negative_regulation of Localization of FSHR 1 0.07 0 0
54 INT86996 NGF Regulation of Regulation of DYNLL1 1 0.26 0 0
55 INT244690 FSHB Positive_regulation of KDSR 1 0.00 0 0
56 INT350116 FSHR Positive_regulation of Gene_expression of CGA 1 0.01 1.28 0
57 INT333450 ATM Positive_regulation of Negative_regulation of MDM2 1 0.18 0 0
58 INT333460 ATM Positive_regulation of Negative_regulation of CHEK2 1 0.14 0 0
59 INT284892 AMH Regulation of Localization of FSHR 1 0.01 0.18 0
60 INT356140 Fshb Regulation of FSHR 1 0.04 0.28 0
61 INT44233 Binding of FSHR and TRH 1 0.34 0.9 0
62 INT228109 Binding of Atm and Chrm2 1 0.09 0.21 0
63 INT334917 GNRHR Positive_regulation of Gene_expression of FSHR 1 0.05 0.53 0
64 INT270758 GNRHR Positive_regulation of Localization of FSHR 1 0.08 0.68 0
65 INT176569 Binding of FSHR and Cyp19a1 1 0.04 0.06 0
66 INT295432 FSHR Positive_regulation of PCOS1 1 0.06 1.24 0
67 INT333458 ATM Positive_regulation of MDM2 1 0.25 0 0
68 INT187669 FSHR Positive_regulation of DBT 1 0.03 0 0
69 INT350122 GNRH1 Negative_regulation of Localization of FSHR 1 0.05 0.99 0
70 INT44232 FSHR Regulation of PLOD1 1 0.15 0.9 0
71 INT78634 ATM Positive_regulation of AGT 1 0.17 0.16 0
72 INT44229 TRH Regulation of FSHR 1 0.11 0.9 0
73 INT187670 Gene_expression of FSHR Positive_regulation of Gene_expression of CYP19A1 1 0.16 0 0
74 INT207813 Atm Regulation of Gene_expression of Parp1 1 0.44 0.31 0
75 INT44231 Negative_regulation of Binding of FSHR and TRH 1 0.39 0.91 0
76 INT333452 ATM Positive_regulation of Negative_regulation of TP53 1 0.18 0 0
77 INT252549 ATM Positive_regulation of Positive_regulation of CHEK2 1 0.02 0 0
78 INT207814 Negative_regulation of Parp1 Positive_regulation of Positive_regulation of Atm 1 0.53 0.08 0
79 INT295431 FSHR Positive_regulation of CGA 1 0.29 0.27 0
80 INT207812 Binding of Parp1 and Atm 1 0.54 0.99 0
81 INT326282 BCL2L10 Negative_regulation of Pnlip 1 0.11 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for female gamete generation. They are ordered first by their pain relevance and then by number of times they were reported in female gamete generation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1644 Regulation of FSHR 77 0.55 15.62 21.49
2 INT912 Localization of FSHR 91 0.79 23.61 15.58
3 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33
4 INT11918 Localization of CGB 35 0.51 8.21 15.01
5 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04
6 INT1647 Negative_regulation of FSHR 54 0.45 13.44 8.87
7 INT13346 Regulation of Localization of CGB 18 0.30 1.29 8.32
8 INT924 Regulation of Localization of FSHR 15 0.45 1.4 5.07
9 INT923 Positive_regulation of Localization of FSHR 14 0.43 2.48 4.96
10 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39
11 INT16235 Positive_regulation of CGB 27 0.70 15.71 4.06
12 INT4632 Regulation of CGB 9 0.38 1.81 3.53
13 INT1646 Negative_regulation of Localization of FSHR 17 0.58 7.36 3.46
14 INT4771 Gene_expression of CGB 23 0.67 14.22 3.42
15 INT30077 Positive_regulation of Localization of CGB 5 0.34 0.42 3.07
16 INT27260 Gene_expression of DYNLL1 8 0.75 7.72 2.78
17 INT22739 Positive_regulation of DYNLL1 5 0.67 1.69 2.67
18 INT15606 Localization of FSHB 24 0.78 9.16 2.49
19 INT15604 Gene_expression of FSHB 30 0.56 9.7 2.45
20 INT86999 Regulation of DYNLL1 5 0.44 2.85 2.18
21 INT138605 Negative_regulation of Phosphorylation of BCL2L10 3 0.26 2.28 2.13
22 INT138607 Phosphorylation of BCL2L10 3 0.36 2.27 2.1
23 INT22738 Negative_regulation of DYNLL1 17 0.57 6.68 2.06
24 INT23491 Positive_regulation of FSHB 14 0.65 7.2 1.79
25 INT33496 Positive_regulation of Gene_expression of FSHR 14 0.46 6.05 1.66
26 INT7033 Binding of FSHR 19 0.37 6.66 1.52
27 INT108556 Negative_regulation of BCL2L10 8 0.32 7.77 1.49
28 INT1641 Positive_regulation of Negative_regulation of FSHR 3 0.41 1.7 1.43
29 INT159186 Positive_regulation of Gene_expression of DYNLL1 1 0.49 1.25 1.4
30 INT9040 Negative_regulation of CGB 9 0.51 2.71 1.29
31 INT152255 Gene_expression of ATM 14 0.71 12.53 1.26
32 INT108554 Gene_expression of BCL2L10 6 0.58 3.18 1.25
33 INT25032 Negative_regulation of Gene_expression of FSHR 11 0.39 1.99 1.2
34 INT23495 Positive_regulation of Localization of FSHB 7 0.40 0.4 1.07
35 INT108557 Negative_regulation of Gene_expression of BCL2L10 2 0.32 1.21 1.07
36 INT75251 Negative_regulation of Positive_regulation of DYNLL1 1 0.41 0.18 0.99
37 INT35299 Regulation of Positive_regulation of FSHR 1 0.05 0 0.91
38 INT25030 Negative_regulation of Negative_regulation of FSHR 2 0.25 0 0.79
39 INT28118 Binding of Atm 13 0.38 12.24 0.68
40 INT34892 Transcription of FSHR 2 0.27 0.08 0.68
41 INT23492 Negative_regulation of Localization of FSHB 2 0.42 0.73 0.66
42 INT32612 Negative_regulation of FSHB 3 0.41 2.17 0.58
43 INT29619 Negative_regulation of Gene_expression of FSHB 5 0.05 0.59 0.57
44 INT48212 Binding of ATM 5 0.47 3.89 0.57
45 INT45778 Negative_regulation of Positive_regulation of CGB 1 0.09 0 0.57
46 INT160778 Transcription of ATM 1 0.40 1.03 0.57
47 INT16251 Negative_regulation of Localization of CGB 2 0.00 0.1 0.56
48 INT15608 Regulation of Gene_expression of CGB 2 0.13 0 0.53
49 INT160776 Positive_regulation of Positive_regulation of ATM 2 0.43 0.94 0.53
50 INT34890 Regulation of Transcription of FSHR 1 0.17 0 0.52
51 INT315892 Negative_regulation of Binding of ATM 1 0.07 1.41 0.4
52 INT154768 Negative_regulation of ATM 10 0.57 7.05 0.39
53 INT112327 Positive_regulation of Gene_expression of FSHB 5 0.44 3.64 0.39
54 INT144275 Negative_regulation of Atm 9 0.59 8.48 0.36
55 INT25047 Positive_regulation of Regulation of FSHR 3 0.31 0.92 0.29
56 INT167438 Localization of ATM 3 0.55 1.61 0.27
57 INT197121 Positive_regulation of Atm 24 0.69 6.81 0.25
58 INT35719 Gene_expression of Atm 34 0.78 15.75 0.24
59 INT7977 Regulation of Gene_expression of FSHR 4 0.44 0.79 0.24
60 INT124643 Binding of DYNLL1 3 0.36 0.9 0.23
61 INT212092 Negative_regulation of Protein_catabolism of BCL2L10 1 0.04 0.82 0.22
62 INT287456 Binding of BCL2L10 9 0.42 4.66 0.19
63 INT97578 Regulation of FSHB 3 0.26 1.41 0.17
64 INT7036 Negative_regulation of Regulation of FSHR 2 0.29 0.14 0.17
65 INT212096 Protein_catabolism of BCL2L10 1 0.06 0.81 0.17
66 INT97577 Regulation of Localization of FSHB 1 0.59 0.79 0.13
67 INT278288 Regulation of Localization of ATM 1 0.09 0.95 0.13
68 INT167440 Regulation of ATM 2 0.20 0.68 0.12
69 INT210482 Regulation of Regulation of FSHR 1 0.03 0.07 0.12
70 INT151342 Positive_regulation of Positive_regulation of FSHR 5 0.20 1.79 0.11
71 INT124295 Positive_regulation of Positive_regulation of CGB 1 0.14 0.55 0.1
72 INT207804 Negative_regulation of Gene_expression of Atm 2 0.59 6.22 0.09
73 INT102037 Localization of DYNLL1 2 0.78 0.32 0.08
74 INT207806 Phosphorylation of Atm 8 0.81 3.07 0.06
75 INT228064 Positive_regulation of Positive_regulation of FSHB 2 0.29 0.84 0.05
76 INT258044 Regulation of BCL2L10 3 0.34 2.26 0.04
77 INT212459 Positive_regulation of Binding of Atm 1 0.40 0.88 0.04
78 INT207803 Regulation of Atm 3 0.41 1.15 0.03
79 INT207807 Localization of Atm 4 0.74 0.21 0
80 INT151097 Positive_regulation of BCL2L10 3 0.44 1.43 0
81 INT200108 Binding of CGB 2 0.11 1.22 0
82 INT157290 Regulation of Gene_expression of ATM 2 0.44 0.86 0
83 INT252642 Transcription of Atm 1 0.53 0.18 0
84 INT354742 Phosphorylation of ATM 1 0.50 1.74 0
85 INT326281 Regulation of Gene_expression of BCL2L10 1 0.34 0.25 0
86 INT176565 Protein_catabolism of FSHR 1 0.26 0.13 0
87 INT132329 Regulation of Negative_regulation of FSHR 1 0.13 0.17 0
88 INT252645 Positive_regulation of Gene_expression of Atm 1 0.50 2.35 0
89 INT102038 Negative_regulation of Localization of DYNLL1 1 0.42 0.24 0
90 INT293633 Localization of BCL2L10 1 0.65 1.02 0
91 INT243479 Phosphorylation of FSHB 1 0.17 1.43 0
92 INT252644 Regulation of Gene_expression of Atm 1 0.27 0.39 0
93 INT207808 Positive_regulation of Positive_regulation of Atm 1 0.50 0.08 0
94 INT293632 Positive_regulation of Gene_expression of BCL2L10 1 0.44 0.62 0
95 INT258073 Negative_regulation of Negative_regulation of BCL2L10 1 0.07 1.35 0
96 INT252643 Negative_regulation of Positive_regulation of Atm 1 0.38 0.6 0
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