GO:0007338

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Name single fertilization
Categary Process
Go Slim No
Go Link GO:0007338
Unique Molecular Interactions 38
Total Molecular Interactions 55
Total Single Events 638
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for single fertilization. They are ordered first by their pain relevance and then by number of times they were reported for single fertilization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT174450 Positive_regulation of Binding of Cxcr3 and Smcp 1 0.18 2.83 1.49
2 INT266742 GOPC Regulation of Positive_regulation of ACR 1 0.02 0.36 1.05
3 INT289173 PYCARD Regulation of MFGE8 1 0.05 0 0.96
4 INT174454 Binding of Cxcr3 and Smcp 1 0.14 1.41 0.74
5 INT174455 Smcp Positive_regulation of Gene_expression of Cxcr3 1 0.17 1.31 0.71
6 INT174453 Smcp Positive_regulation of Cxcr3 1 0.17 1.29 0.64
7 INT253165 SCN10A Positive_regulation of OVGP1 1 0.06 1.34 0.61
8 INT239474 Binding of ACR and Ifx 1 0.02 0.36 0.45
9 INT289178 Regulation of PYCARD Regulation of MFGE8 1 0.05 0 0.32
10 INT349537 Smcp Positive_regulation of Tnfsf10 1 0.38 3.48 0.28
11 INT289174 PYCARD Positive_regulation of MFGE8 1 0.05 0 0.21
12 INT349538 Smcp Positive_regulation of Positive_regulation of Casp9 1 0.04 0.68 0.18
13 INT289176 PYCARD Regulation of Localization of MFGE8 1 0.05 0 0.18
14 INT349539 Smcp Positive_regulation of Positive_regulation of Casp8 1 0.04 0.68 0.18
15 INT208264 Park7 Negative_regulation of Pten 1 0.16 1.16 0.15
16 INT278265 Binding of Fgf2 and Smcp 1 0.03 0.26 0.14
17 INT204996 Binding of Park7 and Pink1 2 0.34 1.09 0.11
18 INT204904 Tlr4 Positive_regulation of Hexb 1 0.14 0.09 0.09
19 INT204884 Tlr4 Negative_regulation of Negative_regulation of Hexb 1 0.13 0.09 0.09
20 INT38206 Acr Negative_regulation of Txnrd1 1 0.20 0.08 0.08
21 INT355828 Binding of MFGE8 and SEA 1 0.01 0.07 0.07
22 INT112644 INS Negative_regulation of OVGP1 1 0.43 0 0.05
23 INT204906 Tlr4 Negative_regulation of Hexb 1 0.13 0.09 0.04
24 INT317301 Binding of Park2 and Park7 1 0.36 0.62 0
25 INT255549 Musd1 Positive_regulation of OVGP1 1 0.01 0.2 0
26 INT317316 Park7 Positive_regulation of Protein_catabolism of Hmbs 1 0.11 0.68 0
27 INT278264 Gene_expression of Ntf3 Positive_regulation of Smcp 1 0.02 0.32 0
28 INT349530 Tnfsf10 Negative_regulation of Smcp 1 0.28 0.88 0
29 INT349535 Binding of Smcp and Tnfsf10 1 0.36 6.79 0
30 INT317324 Park7 Positive_regulation of Protein_catabolism of SNCAIP 1 0.38 0.69 0
31 INT298081 Binding of OVGP1 and Ggt5 1 0.01 0 0
32 INT349532 Positive_regulation of Binding of Smcp and Tnfsf10 1 0.35 2.16 0
33 INT317308 Binding of Park7 and Mul1 1 0.01 0.62 0
34 INT200868 Binding of Cd9 and 4632428N05Rik 1 0.02 0.13 0
35 INT298082 Regulation of Binding of OVGP1 and Ggt5 1 0.01 0 0
36 INT349296 Binding of CSF2 and PARK7 1 0.24 1.24 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for single fertilization. They are ordered first by their pain relevance and then by number of times they were reported in single fertilization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117598 Regulation of ACR 118 0.26 41.25 48.01
2 INT163134 Gene_expression of ACR 78 0.65 30.39 38.48
3 INT195226 Positive_regulation of ACR 23 0.26 7.85 12.62
4 INT174423 Gene_expression of Smcp 39 0.48 29.45 6.06
5 INT113254 Positive_regulation of MFGE8 13 0.09 2.52 5.56
6 INT266746 Binding of ACR 8 0.23 3.44 5.26
7 INT289208 Gene_expression of MFGE8 13 0.08 0.25 3.7
8 INT211192 Localization of ACR 8 0.73 3.04 3.03
9 INT266745 Regulation of Gene_expression of ACR 6 0.10 1.53 2.87
10 INT38204 Gene_expression of Acr 4 0.66 4.23 2.85
11 INT289211 Localization of MFGE8 11 0.09 0.19 2.69
12 INT194586 Negative_regulation of ACR 8 0.26 2.04 2.41
13 INT174446 Positive_regulation of Smcp 7 0.33 5.47 2.24
14 INT258404 Positive_regulation of Gene_expression of ACR 4 0.28 1.08 2.24
15 INT289207 Binding of MFGE8 1 0.06 0 1.92
16 INT174415 Transcription of Smcp 1 0.23 3.52 1.9
17 INT242978 Positive_regulation of OVGP1 7 0.28 3.57 1.81
18 INT299751 Positive_regulation of Positive_regulation of ACR 1 0.05 0.78 1.59
19 INT174434 Localization of Smcp 6 0.53 2.45 1.46
20 INT112645 Negative_regulation of OVGP1 7 0.33 3.17 1.34
21 INT164706 Positive_regulation of Park7 2 0.50 2.28 1.28
22 INT194591 Negative_regulation of Gene_expression of ACR 2 0.07 0.33 1.23
23 INT289209 Regulation of MFGE8 3 0.05 0.2 1.13
24 INT113256 Negative_regulation of Positive_regulation of MFGE8 2 0.08 0.25 0.95
25 INT174424 Binding of Smcp 9 0.25 2.68 0.94
26 INT289205 Negative_regulation of MFGE8 4 0.05 0 0.94
27 INT278254 Positive_regulation of Localization of Smcp 1 0.24 0 0.85
28 INT204863 Gene_expression of Hexb 3 0.44 2.57 0.52
29 INT215854 Positive_regulation of Gene_expression of Hexb 1 0.34 2.42 0.52
30 INT195228 Negative_regulation of Positive_regulation of ACR 1 0.10 0.82 0.49
31 INT116427 Negative_regulation of Smcp 10 0.31 2.72 0.41
32 INT278253 Positive_regulation of Gene_expression of Smcp 3 0.29 1.24 0.39
33 INT289192 Negative_regulation of Gene_expression of MFGE8 1 0.05 0 0.39
34 INT258403 Negative_regulation of Localization of ACR 1 0.24 0.92 0.38
35 INT258408 Positive_regulation of Regulation of ACR 1 0.26 0.07 0.36
36 INT289212 Regulation of Localization of MFGE8 1 0.05 0 0.34
37 INT289206 Positive_regulation of Localization of MFGE8 1 0.06 0 0.34
38 INT289210 Negative_regulation of Localization of MFGE8 1 0.05 0 0.33
39 INT174440 Negative_regulation of Positive_regulation of Smcp 1 0.14 0.65 0.32
40 INT174436 Positive_regulation of Negative_regulation of Smcp 1 0.15 0.65 0.32
41 INT349301 Negative_regulation of PARK7 1 0.41 3.44 0.26
42 INT289199 Regulation of Binding of MFGE8 1 0.05 0 0.24
43 INT289203 Regulation of Gene_expression of MFGE8 1 0.05 0 0.21
44 INT161264 Localization of Hexb 2 0.40 0.94 0.18
45 INT345939 Negative_regulation of Regulation of ACR 1 0.01 0.52 0.18
46 INT161265 Negative_regulation of Localization of Hexb 1 0.29 0.88 0.16
47 INT281868 Negative_regulation of Park7 1 0.00 1.69 0.14
48 INT349300 Gene_expression of PARK7 1 0.75 8.65 0.12
49 INT204986 Gene_expression of Park7 5 0.38 5.48 0.1
50 INT173981 Gene_expression of Park7 2 0.56 0.73 0.1
51 INT104405 Positive_regulation of Acr 3 0.28 0.47 0.09
52 INT255536 Gene_expression of OVGP1 3 0.65 0.81 0.09
53 INT278252 Regulation of Smcp 2 0.29 1.58 0.09
54 INT255554 Negative_regulation of Cd9 1 0.20 0.22 0.09
55 INT200867 Gene_expression of Cd9 12 0.60 1.94 0.08
56 INT255553 Regulation of Gene_expression of Cd9 1 0.13 0.28 0.08
57 INT243711 Binding of Park7 3 0.25 1.5 0.06
58 INT204990 Positive_regulation of Gene_expression of Park7 2 0.24 1.79 0.05
59 INT204858 Negative_regulation of Hexb 1 0.16 0.09 0.04
60 INT255533 Binding of OVGP1 1 0.19 0.27 0.04
61 INT255524 Positive_regulation of Binding of OVGP1 1 0.25 0 0.04
62 INT204973 Positive_regulation of Park7 2 0.23 1.62 0.03
63 INT319365 Regulation of Gene_expression of Smcp 3 0.32 0.53 0
64 INT38205 Negative_regulation of Acr 3 0.50 0.1 0
65 INT204970 Localization of Park7 3 0.54 2.76 0
66 INT130131 Regulation of Acr 2 0.11 0.2 0
67 INT319367 Negative_regulation of Gene_expression of Smcp 2 0.30 0.71 0
68 INT349303 Positive_regulation of Positive_regulation of PARK7 1 0.49 1 0
69 INT200866 Positive_regulation of Cd9 1 0.39 0 0
70 INT179206 Binding of Acr 1 0.21 0 0
71 INT349298 Phosphorylation of PARK7 1 0.79 0.9 0
72 INT97888 Localization of Acr 1 0.11 0 0
73 INT349304 Positive_regulation of PARK7 1 0.67 9.44 0
74 INT204868 Negative_regulation of Gene_expression of Hexb 1 0.18 0.09 0
75 INT298077 Positive_regulation of Gene_expression of OVGP1 1 0.08 0 0
76 INT349527 Phosphorylation of Smcp 1 0.58 1.93 0
77 INT208272 Regulation of Gene_expression of Park7 1 0.19 0.27 0
78 INT349302 Localization of PARK7 1 0.78 3.09 0
79 INT349299 Binding of PARK7 1 0.41 1.86 0
80 INT200844 Positive_regulation of Gene_expression of Cd9 1 0.39 0 0
81 INT298078 Localization of OVGP1 1 0.11 0.33 0
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