GO:0007346

From wiki-pain
Jump to: navigation, search
Name regulation of mitotic cell cycle
Categary Process
Go Slim No
Go Link GO:0007346
Unique Molecular Interactions 316
Total Molecular Interactions 450
Total Single Events 2688
Pain Genes Associated 22

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for regulation of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
2 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
3 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
4 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
5 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 0.29 0.97 0.94
6 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
7 INT116269 Binding of Myc and Mycbp2 1 0.19 0.5 0.87
8 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
9 INT139079 Tnip1 Negative_regulation of Ptch1 1 0.20 0.63 0.62
10 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
11 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
12 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 0.32 0.83 0.61
13 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
14 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 0.32 0.83 0.61
15 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
16 INT54942 Rb1 Regulation of Gab1 1 0.02 0.39 0.59
17 INT73654 Binding of Jun and Pim3 1 0.02 0.99 0.58
18 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
19 INT319554 Sgk1 Regulation of Cdkn1a 1 0.26 0.09 0.45
20 INT85782 Rb1 Regulation of PRKG1 1 0.00 0.38 0.37
21 INT85778 Rb1 Regulation of Prkaca 1 0.00 0.38 0.36
22 INT85779 Rb1 Regulation of Prkcg 1 0.01 0.38 0.36
23 INT204080 HP Negative_regulation of Phosphorylation of Rb1 1 0.00 3.53 0.34
24 INT119262 PPM1E Negative_regulation of Positive_regulation of CDKN1A 1 0.01 0.96 0.33
25 INT54943 Gab1 Regulation of Rb1 1 0.02 0.2 0.31
26 INT73652 Jun Positive_regulation of Pim3 1 0.02 0.48 0.29
27 INT73651 Fos Positive_regulation of Pim3 1 0.04 0.48 0.29
28 INT73655 Binding of Pim3 and Fos 1 0.03 0.49 0.28
29 INT172977 Cdkn1a Negative_regulation of Positive_regulation of Inca1 1 0.00 1.39 0.27
30 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
31 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
32 INT327300 Binding of Hnrnpd and Myc 1 0.12 1.02 0.25
33 INT245555 Runx1 Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
34 INT245565 Runx1 Negative_regulation of Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
35 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
36 INT306067 Binding of ADH5 and CYLD 1 0.02 3.13 0.19
37 INT212084 NOXO1 Positive_regulation of CDKN1A 1 0.06 0.53 0.19
38 INT230455 FOXG1 Negative_regulation of HBS1L 1 0.02 1.73 0.18
39 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
40 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
41 INT119264 Binding of RB1 and PPM1E 1 0.00 0.46 0.17
42 INT119263 Binding of CDKN1A and PPM1E 1 0.01 0.46 0.17
43 INT221899 Rb1 Positive_regulation of Transcription of Ccl20 1 0.01 0.62 0.16
44 INT221908 Rb1 Positive_regulation of Transcription of TNIP2 1 0.01 0.62 0.16
45 INT116268 Binding of Myc and Acsl1 1 0.08 0.19 0.16
46 INT289525 Sirt1 Negative_regulation of Negative_regulation of Ucp2 1 0.32 0.86 0.15
47 INT255258 Binding of Rb1 and Tsp1 1 0.38 0.95 0.15
48 INT310263 Rb1 Negative_regulation of Gene_expression of Tnf 1 0.07 0.97 0.15
49 INT123192 Bmp6 Positive_regulation of CDKN1A 1 0.18 0.61 0.14
50 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14
51 INT193789 SDF2L1 Positive_regulation of CDKN1A 1 0.00 0.68 0.13
52 INT201722 Myc Regulation of Gene_expression of Ccnd1 1 0.03 0.79 0.13
53 INT320261 Binding of Myc and Ntrk2 1 0.01 0.36 0.13
54 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
55 INT193785 SDF2L1 Positive_regulation of Gene_expression of CDKN1A 1 0.00 0.68 0.13
56 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
57 INT173200 PPA1 Positive_regulation of Myc 1 0.08 0.5 0.12
58 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
59 INT289539 Negative_regulation of Sirt1 Negative_regulation of Gene_expression of Agrp 1 0.29 0.47 0.09
60 INT221653 Binding of Myc and Gopc 2 0.12 0.51 0.08
61 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
62 INT270457 Binding of Ptch1 and Gli1 1 0.02 1.3 0.08
63 INT238392 RB1 Regulation of E2F2 1 0.01 0.36 0.08
64 INT237922 TNFSF10 Positive_regulation of CDKN1A 1 0.09 3.28 0.08
65 INT289536 Sirt1 Negative_regulation of Localization of Pparg 1 0.13 0.43 0.08
66 INT255256 Positive_regulation of Binding of Rb1 and Tsp1 1 0.50 0.48 0.08
67 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08
68 INT289603 Sirt1 Negative_regulation of Localization of PPARG 1 0.02 0.43 0.08
69 INT289540 Sirt1 Negative_regulation of Localization of Ins1 1 0.03 0.43 0.08
70 INT289533 Sirt1 Negative_regulation of Pparg 1 0.18 0.42 0.07
71 INT256160 Positive_regulation of Binding of Pgc and Sirt1 1 0.55 0.21 0.07
72 INT238207 Binding of Bmx and Sik1 1 0.01 0.43 0.07
73 INT289602 Sirt1 Negative_regulation of PPARG 1 0.02 0.37 0.07
74 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07
75 INT277615 Positive_regulation of Binding of ZNF238 and Hdac3 1 0.38 0.06 0.07
76 INT256161 Binding of Pgc and Sirt1 1 0.38 0.21 0.07
77 INT277614 Binding of ZNF238 and Hdac3 1 0.29 0.06 0.07
78 INT193783 ITIH4 Regulation of Gene_expression of CDKN1A 1 0.03 0.55 0.07
79 INT119268 CDKN1A Regulation of CREBBP 1 0.21 0.44 0.07
80 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
81 INT302160 LAMTOR1 Regulation of CDKN1A 1 0.08 0.26 0.06
82 INT307223 CYLD Positive_regulation of Localization of BCL3 1 0.12 0.51 0.06
83 INT307226 CYLD Negative_regulation of Localization of BCL3 1 0.10 0.45 0.06
84 INT302127 MRPL28 Regulation of CDKN1A 1 0.09 0.26 0.06
85 INT76862 Dynll1 Positive_regulation of Rb1 1 0.37 0.1 0.06
86 INT257867 Negative_regulation of Eif4e Positive_regulation of Rb1 1 0.05 0.54 0.06
87 INT197617 Binding of S100a6 and Rb1 1 0.03 0 0.06
88 INT238208 Sik1 Positive_regulation of Positive_regulation of Bmx 1 0.01 0 0.05
89 INT298806 Binding of Hdac3 and Rb1 1 0.02 0.77 0.05
90 INT302130 CDKN1A Regulation of CDKN1B 1 0.04 0.26 0.05
91 INT302176 CDKN1C Regulation of CDKN1A 1 0.09 0.26 0.05
92 INT340293 Binding of Ins1 and Sirt1 1 0.25 1.25 0.05
93 INT302163 IFI27 Regulation of CDKN1A 1 0.11 0.26 0.05
94 INT292815 Binding of CDC123 and FTO 1 0.50 0.48 0.05
95 INT253023 Binding of PTTG1 and Myc 1 0.16 0.22 0.04
96 INT238211 Binding of STAT3 and Sik1 1 0.04 0.25 0.04
97 INT169962 Binding of Rb1 and E2f4 1 0.25 0.56 0.04
98 INT302291 Positive_regulation of EGFR Positive_regulation of Myc 1 0.18 1.3 0.04
99 INT289541 Sirt1 Regulation of Gene_expression of Agrp 1 0.41 0.52 0.04
100 INT289538 Sirt1 Positive_regulation of Stat3 1 0.34 0.37 0.04
101 INT333848 Binding of Ccna1 and Rb1 1 0.04 0.48 0.04
102 INT176224 Binding of CDKN1A and PCNA 4 0.08 2.52 0.03
103 INT302159 TSC1 Positive_regulation of Transcription of CDKN1A 1 0.00 0.28 0.03
104 INT255756 Ptch1 Positive_regulation of Phosphorylation of Pik3r1 1 0.16 1.08 0.03
105 INT303091 Rorb Regulation of CDKN1A 1 0.00 0.52 0.03
106 INT202270 Pttg1 Positive_regulation of Myc 1 0.28 0.84 0.03
107 INT255733 Ptch1 Positive_regulation of Pik3r1 1 0.16 1.08 0.03
108 INT283722 Id2 Negative_regulation of Transcription of CDKN1A 1 0.45 0.11 0.03
109 INT197587 Ppt1 Positive_regulation of Rb1 1 0.18 0 0.03
110 INT238395 BAX Regulation of CDKN1A 1 0.03 0.31 0.03
111 INT173199 CNOT4 Regulation of Regulation of Myc 1 0.01 0.66 0.03
112 INT197593 Dlat Positive_regulation of Rb1 1 0.04 0 0.03
113 INT289542 Sirt1 Negative_regulation of Stat3 1 0.32 0.31 0.03
114 INT94157 CDCP1 Negative_regulation of RB1 1 0.02 0.92 0.03
115 INT289526 Binding of Arc and Sirt1 1 0.08 0.55 0.03
116 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03
117 INT94159 Positive_regulation of CDK1 Negative_regulation of RB1 1 0.45 0.93 0.03
118 INT94158 CDK1 Negative_regulation of RB1 1 0.41 0.92 0.03
119 INT289599 Sirt1 Positive_regulation of Ppargc1a 1 0.51 0.36 0.03
120 INT223066 CDKN1A Negative_regulation of CCND1 1 0.04 0.66 0.03
121 INT238393 Binding of E2F2 and RB1 3 0.04 0.24 0
122 INT201771 CDKN1A Positive_regulation of Localization of Ccnd1 1 0.04 0 0
123 INT180040 Binding of D7Cwr3P and Sirt1 1 0.00 0 0
124 INT225610 Ncoa6 Regulation of Rb1 1 0.03 0.21 0
125 INT233276 Cdkn1a Regulation of Hoxa10 1 0.12 0.26 0
126 INT182942 VDR Positive_regulation of CDKN1A 1 0.35 0.38 0
127 INT300696 Sirt1 Regulation of Cyb5r3 1 0.03 0 0
128 INT104540 FOXG1 Regulation of Lipc 1 0.02 0 0
129 INT255758 Ptch1 Positive_regulation of Akt1 1 0.21 1.14 0
130 INT238402 ELANE Positive_regulation of Gene_expression of CDKN1A 1 0.03 0.48 0
131 INT332881 Negative_regulation of Binding of Hdac3 and Ncor1 1 0.28 0.18 0
132 INT299444 Foxl2 Positive_regulation of Sirt1 1 0.24 0.31 0
133 INT289600 Negative_regulation of Binding of Sirt1 and Sirt1 1 0.47 1.17 0
134 INT301244 Rb1 Regulation of Hbp1 1 0.03 0.75 0
135 INT299458 Gene_expression of Sirt1 Negative_regulation of Foxl2 1 0.25 0.32 0
136 INT277691 Cdkn1a Negative_regulation of Positive_regulation of Casp3 1 0.00 1.01 0
137 INT255732 Ptch1 Positive_regulation of hs 1 0.06 1.26 0
138 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
139 INT225157 CDKN1A Regulation of CHKA 1 0.12 0.58 0
140 INT329898 MIRLET7C Regulation of Myc 1 0.49 0.62 0
141 INT334322 Binding of RB1 and TP53 1 0.34 2 0
142 INT204325 Binding of PPARGC1A and SIRT1 1 0.39 0.19 0
143 INT298197 EGFR Regulation of CDKN1A 1 0.04 1.14 0
144 INT179095 Myc Positive_regulation of Gene_expression of Trp53 1 0.43 0.83 0
145 INT273774 Binding of GPER and RB1 1 0.01 0.45 0
146 INT205975 Binding of PTCH1 and Smo 1 0.02 0.72 0
147 INT214892 Positive_regulation of HGF Positive_regulation of CDKN1A 1 0.17 0.31 0
148 INT305542 Binding of Rb1 and Trp53 1 0.00 0.9 0
149 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0
150 INT176292 Fasl Regulation of Gene_expression of CDKN1A 1 0.34 0.84 0
151 INT221648 Binding of Myc and Sh2 1 0.05 0 0
152 INT315159 Erbb2 Negative_regulation of Myc 1 0.43 0.84 0
153 INT169963 Positive_regulation of Binding of Rb1 and Rbl2 1 0.33 0.1 0
154 INT255755 Ptch1 Regulation of Positive_regulation of Ins1 1 0.05 0.28 0
155 INT289534 Sirt1 Regulation of Regulation of Pomc 1 0.04 0.15 0
156 INT214918 Gtf3a Positive_regulation of CDKN1A 1 0.01 0.66 0
157 INT220819 Myc Regulation of Transcription of Tert 1 0.44 0.1 0
158 INT260522 Binding of Myc and Prnp 1 0.30 0.35 0
159 INT306825 Positive_regulation of Binding of E2F2 and RB1 1 0.04 0.05 0
160 INT205958 GLI1 Positive_regulation of Gene_expression of PTCH1 1 0.35 0.57 0
161 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
162 INT256165 Binding of Sirt6 and Sirt1 1 0.13 0.58 0
163 INT307222 CYLD Regulation of Negative_regulation of BCL3 1 0.10 0.3 0
164 INT196958 Phosphorylation of Rb1 Positive_regulation of Localization of E2f1 1 0.45 0.44 0
165 INT307225 CYLD Regulation of TNFRSF11A 1 0.14 0.81 0
166 INT260520 Binding of Myc and Scarb1 1 0.33 0.16 0
167 INT169959 Binding of Rb1 and Rbl2 1 0.26 0.1 0
168 INT318218 SIRT1 Positive_regulation of Binding of FOXO3 1 0.44 0.51 0
169 INT322597 Myc Negative_regulation of Gene_expression of CFLAR 1 0.11 1.35 0
170 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
171 INT289518 Arc Regulation of Sirt1 1 0.10 0.56 0
172 INT333448 RB1 Positive_regulation of TFDP1 1 0.05 0 0
173 INT330696 Phosphorylation of RB1 Positive_regulation of Gene_expression of E2F2 1 0.01 1 0
174 INT182912 Binding of CDKN1A and FRA8E 1 0.02 0.37 0
175 INT289537 Lep Negative_regulation of Sirt1 1 0.20 0.05 0
176 INT179093 Myc Positive_regulation of Vps54 1 0.02 2.31 0
177 INT233274 Tpt1 Regulation of Cdkn1a 1 0.05 0.26 0
178 INT214890 GOPC Positive_regulation of CDKN1A 1 0.06 0.57 0
179 INT179094 Gene_expression of Myc Positive_regulation of Vps54 1 0.02 0.54 0
180 INT172464 Binding of Rab27a and Myc 1 0.13 0.69 0
181 INT318219 SIRT1 Regulation of TBK1 1 0.03 0.43 0
182 INT339977 Positive_regulation of Binding of HDAC3 and HDAC7 1 0.23 0.52 0
183 INT325152 CDKN1A Negative_regulation of CCNE2 1 0.07 0.1 0
184 INT255753 Ptch1 Positive_regulation of Phosphorylation of Gopc 1 0.13 1.33 0
185 INT196955 Binding of E2f1 and Rb1 1 0.36 1 0
186 INT301365 Stat1 Positive_regulation of Cdkn1a 1 0.03 0.38 0
187 INT330698 PCNA Regulation of RB1 1 0.00 0.3 0
188 INT179090 Positive_regulation of Myc Regulation of Gene_expression of Trp53 1 0.23 0.69 0
189 INT214891 HGF Positive_regulation of CDKN1A 1 0.25 1.15 0
190 INT289517 Sirt1 Regulation of Prkag1 1 0.02 0.08 0
191 INT182935 KCNIP3 Regulation of CDKN1A 1 0.45 0.96 0
192 INT204326 SIRT1 Positive_regulation of PPARGC1A 1 0.51 0.19 0
193 INT179091 Binding of Max and Myc 1 0.16 0.52 0
194 INT318221 SIRT1 Positive_regulation of FOXO3 1 0.41 0.63 0
195 INT235166 Binding of Hdac3 and Atxn1 1 0.02 0.28 0
196 INT214919 Pkd1 Positive_regulation of CDKN1A 1 0.51 2.6 0
197 INT196943 E2f1 Negative_regulation of Rb1 1 0.42 0.44 0
198 INT337637 SIRT1 Negative_regulation of TP53 1 0.23 1.49 0
199 INT332894 Binding of Ahrr and Hdac3 1 0.01 0.08 0
200 INT179096 Positive_regulation of Myc Positive_regulation of Positive_regulation of Vps54 1 0.02 1.14 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in regulation of mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
2 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
3 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
4 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
5 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
6 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82
7 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69
8 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
9 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
10 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
11 INT23220 Positive_regulation of FOXG1 10 0.43 2.86 3.49
12 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
13 INT62268 Positive_regulation of Cdkn1a 33 0.67 14.12 3.26
14 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
15 INT29929 Gene_expression of Rb1 20 0.69 5.81 3.1
16 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
17 INT9242 Negative_regulation of FOXG1 13 0.40 1.43 2.86
18 INT36886 Transcription of Myc 6 0.69 3.16 2.86
19 INT75499 Positive_regulation of Positive_regulation of CDKN1A 12 0.60 7.28 2.84
20 INT54938 Regulation of Rb1 6 0.44 4.41 2.69
21 INT73460 Positive_regulation of Gene_expression of Myc 26 0.67 20.44 2.61
22 INT57970 Positive_regulation of Rb1 17 0.67 7.03 2.36
23 INT23219 Regulation of FOXG1 8 0.22 1.32 2.34
24 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31
25 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
26 INT57971 Regulation of Rb1 5 0.41 2.36 1.66
27 INT104331 Negative_regulation of Gene_expression of CDKN1A 24 0.57 13.68 1.63
28 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57
29 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
30 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
31 INT113151 Positive_regulation of Ptch1 7 0.64 3.8 1.41
32 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36
33 INT116265 Binding of Myc 9 0.36 4.28 1.36
34 INT169907 Gene_expression of Rb1 25 0.60 21.95 1.32
35 INT139077 Negative_regulation of Ptch1 5 0.56 5.22 1.29
36 INT63905 Regulation of RB1 13 0.62 12.67 1.28
37 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26
38 INT41124 Negative_regulation of Rb1 11 0.44 3.17 1.22
39 INT71848 Positive_regulation of Transcription of Myc 1 0.67 0.16 1.11
40 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
41 INT9243 Gene_expression of FOXG1 14 0.53 7.52 1.02
42 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
43 INT102070 Regulation of Gene_expression of Myc 4 0.60 2.68 0.96
44 INT174188 Positive_regulation of Gene_expression of RB1 9 0.45 6.22 0.94
45 INT17894 Regulation of Myc 10 0.60 5.65 0.93
46 INT181177 Gene_expression of CYLD 5 0.69 24.96 0.89
47 INT135299 Binding of PTCH1 10 0.48 12.16 0.84
48 INT17330 Binding of FOXG1 3 0.33 0.23 0.83
49 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
50 INT169911 Phosphorylation of Rb1 35 0.73 18.58 0.79
51 INT146521 Negative_regulation of Positive_regulation of CDKN1A 6 0.42 3.29 0.79
52 INT70423 Binding of HDAC3 1 0.01 0.36 0.75
53 INT142416 Binding of Ptch1 6 0.34 4.92 0.74
54 INT41123 Positive_regulation of Rb1 12 0.44 3.03 0.73
55 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67
56 INT169931 Localization of Rb1 6 0.70 4.79 0.65
57 INT126732 Regulation of Cdkn1a 6 0.39 2.13 0.63
58 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56
59 INT62266 Phosphorylation of Rb1 4 0.71 2.68 0.54
60 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51
61 INT289580 Negative_regulation of Sirt1 23 0.58 9.03 0.48
62 INT93397 Negative_regulation of Phosphorylation of Rb1 1 0.51 0.32 0.48
63 INT300291 Phosphorylation of Sirt1 1 0.77 6.07 0.45
64 INT97606 Negative_regulation of Cdkn1a 7 0.43 4.24 0.42
65 INT240935 Transcription of Sirt1 2 0.68 0.42 0.42
66 INT340290 Regulation of Transcription of Sirt1 1 0.43 0.13 0.42
67 INT125592 Negative_regulation of Negative_regulation of CDKN1A 2 0.42 2.07 0.41
68 INT194993 Binding of RB1 15 0.37 10.96 0.4
69 INT196916 Negative_regulation of Rb1 13 0.42 14.29 0.4
70 INT90354 Negative_regulation of Myc 6 0.57 4.24 0.4
71 INT117440 Positive_regulation of Cdkn1a 3 0.67 2.95 0.4
72 INT131018 Phosphorylation of Cdkn1a 3 0.61 2.06 0.4
73 INT67793 Binding of Pim3 1 0.03 0 0.4
74 INT181179 Binding of CYLD 4 0.43 7.06 0.39
75 INT41125 Positive_regulation of Localization of Rb1 2 0.38 0.78 0.39
76 INT41126 Localization of Rb1 2 0.61 0.78 0.39
77 INT185432 Negative_regulation of CYLD 4 0.52 3.19 0.35
78 INT240914 Negative_regulation of Sirt1 9 0.46 3.16 0.34
79 INT196925 Positive_regulation of Gene_expression of Rb1 4 0.45 3.16 0.33
80 INT82797 Transcription of CDKN1A 11 0.69 8.01 0.32
81 INT169918 Negative_regulation of Phosphorylation of Rb1 8 0.37 6.64 0.32
82 INT131017 Positive_regulation of Positive_regulation of Cdkn1a 5 0.67 1.89 0.32
83 INT119269 Binding of CDKN1A 14 0.47 8.82 0.31
84 INT289546 Negative_regulation of Gene_expression of Sirt1 5 0.42 3.1 0.31
85 INT204368 Gene_expression of SIRT1 17 0.76 4.48 0.3
86 INT197599 Transcription of Rb1 4 0.63 0.87 0.3
87 INT123529 Phosphorylation of CDKN1A 8 0.80 5.69 0.29
88 INT183055 Gene_expression of PTCH1 10 0.77 15.54 0.26
89 INT187547 Localization of Myc 1 0.68 0.92 0.26
90 INT341565 Negative_regulation of Positive_regulation of CDC123 1 0.20 0.15 0.26
91 INT187548 Regulation of Transcription of Myc 1 0.44 0.68 0.26
92 INT172445 Positive_regulation of Gene_expression of Myc 58 0.70 39.62 0.25
93 INT225177 Regulation of Negative_regulation of CDKN1A 1 0.39 0.26 0.25
94 INT102071 Negative_regulation of Gene_expression of Myc 8 0.57 3.5 0.22
95 INT207163 Regulation of Gene_expression of Rb1 3 0.39 1.08 0.22
96 INT185452 Regulation of CYLD 6 0.40 6.09 0.21
97 INT289551 Regulation of Sirt1 8 0.61 4.46 0.2
98 INT104539 Regulation of Positive_regulation of FOXG1 1 0.38 0.2 0.19
99 INT113354 Regulation of Pim3 1 0.02 0 0.19
100 INT293677 Transcription of RB1 1 0.62 0.8 0.18
101 INT246620 Negative_regulation of Positive_regulation of Sirt1 2 0.39 1.9 0.17
102 INT161283 Positive_regulation of Positive_regulation of FOXG1 1 0.02 0 0.17
103 INT298778 Phosphorylation of Hdac3 1 0.44 0.67 0.17
104 INT169930 Binding of Rb1 15 0.43 5.91 0.16
105 INT94168 Positive_regulation of Phosphorylation of RB1 12 0.60 6.6 0.15
106 INT245263 Negative_regulation of Gene_expression of Cdkn1a 5 0.25 1.84 0.14
107 INT256111 Regulation of Gene_expression of Sirt1 1 0.32 0.73 0.14
108 INT307231 Positive_regulation of Gene_expression of CYLD 1 0.45 2.37 0.14
109 INT123181 Positive_regulation of Negative_regulation of CDKN1A 1 0.49 0.6 0.14
110 INT204365 Positive_regulation of Gene_expression of SIRT1 8 0.68 2.9 0.13
111 INT265376 Gene_expression of Hdac3 4 0.51 1.8 0.13
112 INT197627 Localization of RB1 3 0.69 4.16 0.13
113 INT61789 Negative_regulation of Cdkn1a 2 0.41 1.35 0.13
114 INT337484 Gene_expression of HDAC3 2 0.37 0.15 0.13
115 INT341562 Negative_regulation of Gene_expression of HDAC3 1 0.23 0.05 0.13
116 INT341549 Positive_regulation of CDC123 1 0.24 0.08 0.13
117 INT185449 Regulation of Regulation of CYLD 1 0.21 2.03 0.13
118 INT314724 Regulation of Localization of RB1 1 0.15 1.25 0.13
119 INT190563 Regulation of Binding of Rb1 1 0.08 0.7 0.13
120 INT289543 Regulation of Gene_expression of Sirt1 3 0.45 1.81 0.11
121 INT169940 Positive_regulation of Localization of Rb1 2 0.61 1.74 0.11
122 INT289547 Positive_regulation of Positive_regulation of Sirt1 2 0.69 0.76 0.11
123 INT332681 Regulation of Positive_regulation of Sirt1 1 0.16 0.69 0.11
124 INT56346 Gene_expression of Pim3 1 0.01 0.11 0.11
125 INT56345 Negative_regulation of Gene_expression of Pim3 1 0.00 0.11 0.11
126 INT148991 Gene_expression of Cdkn1a 1 0.44 0.46 0.11
127 INT179083 Positive_regulation of Myc 65 0.70 38.78 0.1
128 INT307240 Localization of CYLD 3 0.72 3.09 0.1
129 INT331785 Negative_regulation of Gene_expression of Hdac3 1 0.04 0.86 0.1
130 INT260083 Regulation of PTCH1 11 0.27 4.46 0.09
131 INT41890 Positive_regulation of Gene_expression of FOXG1 2 0.32 1.04 0.09
132 INT257732 Regulation of Positive_regulation of RB1 2 0.39 2.35 0.09
133 INT301361 Phosphorylation of Cdkn1a 2 0.79 1.21 0.09
134 INT289567 Regulation of Negative_regulation of Sirt1 1 0.45 0.74 0.09
135 INT346497 Negative_regulation of Phosphorylation of Cdkn1a 1 0.41 0.83 0.09
136 INT270454 Regulation of Transcription of Ptch1 1 0.25 0.55 0.09
137 INT270450 Transcription of Ptch1 1 0.49 0.55 0.09
138 INT172453 Binding of Myc 6 0.48 2.36 0.08
139 INT185440 Negative_regulation of Negative_regulation of CYLD 1 0.20 1.02 0.08
140 INT165148 Regulation of Binding of Ptch1 1 0.22 0.08 0.08
141 INT270452 Regulation of Gene_expression of Ptch1 1 0.25 0.25 0.08
142 INT238167 Localization of Sik1 1 0.06 0.16 0.07
143 INT62267 Negative_regulation of Gene_expression of Rb1 1 0.12 0.82 0.07
144 INT62265 Negative_regulation of Positive_regulation of Rb1 1 0.12 0.85 0.07
145 INT289574 Negative_regulation of Positive_regulation of Sirt1 1 0.42 0.42 0.07
146 INT238165 Gene_expression of Sik1 1 0.05 0.2 0.07
147 INT256136 Negative_regulation of Binding of Sirt1 1 0.30 0.5 0.07
148 INT101430 Positive_regulation of Negative_regulation of FOXG1 1 0.37 0 0.07
149 INT328542 Regulation of Positive_regulation of Cdkn1a 1 0.03 0.79 0.07
150 INT165154 Negative_regulation of Positive_regulation of Ptch1 1 0.34 0.09 0.07
151 INT183056 Positive_regulation of Transcription of PTCH1 1 0.28 0.46 0.07
152 INT179085 Regulation of Myc 6 0.28 2.83 0.06
153 INT17893 Positive_regulation of Myc 4 0.67 3.28 0.06
154 INT176262 Positive_regulation of Phosphorylation of CDKN1A 3 0.49 2.12 0.06
155 INT197606 Binding of Rb1 2 0.28 0.14 0.06
156 INT255719 Phosphorylation of Ptch1 1 0.32 3.7 0.06
157 INT339991 Localization of SIRT1 1 0.34 0.3 0.06
158 INT185437 Negative_regulation of Gene_expression of CYLD 3 0.52 2.41 0.05
159 INT256137 Positive_regulation of Regulation of Sirt1 1 0.36 0.32 0.05
160 INT201778 Positive_regulation of Phosphorylation of Myc 1 0.49 1.02 0.05
161 INT318236 Negative_regulation of Gene_expression of SIRT1 1 0.42 0.59 0.05
162 INT289587 Negative_regulation of Negative_regulation of Sirt1 1 0.42 0.65 0.05
163 INT256129 Negative_regulation of Gene_expression of Sirt1 1 0.31 0.4 0.05
164 INT255726 Localization of Ptch1 1 0.33 1.74 0.05
165 INT201776 Phosphorylation of Myc 1 0.80 1.01 0.05
166 INT307229 Phosphorylation of CYLD 1 0.73 1.02 0.05
167 INT178299 Transcription of Myc 4 0.63 0.82 0.04
168 INT265372 Localization of Hdac3 3 0.55 0.6 0.04
169 INT178287 Positive_regulation of Transcription of Myc 2 0.47 0.49 0.04
170 INT183070 Transcription of PTCH1 2 0.68 0.95 0.04
171 INT178288 Regulation of Transcription of Myc 1 0.19 0.14 0.04
172 INT245909 Positive_regulation of Transcription of Rb1 1 0.05 0.49 0.04
173 INT332334 Regulation of Binding of Myc 1 0.44 0 0.04
174 INT316430 Positive_regulation of Negative_regulation of Cdkn1a 1 0.19 1.24 0.04
175 INT236701 Negative_regulation of Gene_expression of Rb1 4 0.10 4.55 0.03
176 INT169945 Positive_regulation of Phosphorylation of Rb1 4 0.41 1.75 0.03
177 INT289584 Binding of Sirt1 3 0.48 1.35 0.03
178 INT270038 Positive_regulation of Positive_regulation of Sirt1 2 0.43 0.44 0.03
179 INT265373 Regulation of Hdac3 2 0.17 1.1 0.03
180 INT246622 Phosphorylation of Sirt1 2 0.74 0.56 0.03
181 INT179080 Positive_regulation of Positive_regulation of Myc 1 0.70 5.2 0.03
182 INT224295 Protein_catabolism of CDKN1A 1 0.12 0.55 0.03
183 INT238158 Phosphorylation of Sik1 1 0.06 0.69 0.03
184 INT238181 Binding of Sik1 1 0.04 0.18 0.03
185 INT183064 Regulation of Gene_expression of PTCH1 1 0.34 0.22 0.03
186 INT238182 Positive_regulation of Localization of Sik1 1 0.04 0 0.03
187 INT298776 Regulation of Phosphorylation of Rb1 1 0.04 0.39 0.03
188 INT238161 Positive_regulation of Phosphorylation of Sik1 1 0.04 0 0.03
189 INT204367 Positive_regulation of SIRT1 13 0.68 4.17 0
190 INT204349 Regulation of SIRT1 8 0.61 1.99 0
191 INT179078 Regulation of Gene_expression of Myc 6 0.62 3.02 0
192 INT256134 Localization of Sirt1 5 0.50 2.99 0
193 INT174197 Negative_regulation of Gene_expression of RB1 4 0.47 4.25 0
194 INT172965 Negative_regulation of Positive_regulation of Cdkn1a 4 0.41 1.84 0
195 INT204353 Transcription of SIRT1 3 0.68 0.67 0
196 INT179079 Negative_regulation of Myc 3 0.37 1.92 0
197 INT237226 Gene_expression of Plk1 3 0.59 0.78 0
198 INT179077 Negative_regulation of Gene_expression of Myc 3 0.59 1.36 0
199 INT205968 Negative_regulation of PTCH1 2 0.58 2.35 0
200 INT348463 Protein_catabolism of RB1 2 0.11 2.22 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox