GO:0007389

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Name pattern specification process
Categary Process
Go Slim No
Go Link GO:0007389
Unique Molecular Interactions 531
Total Molecular Interactions 684
Total Single Events 3289
Pain Genes Associated 79

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for pattern specification process. They are ordered first by their pain relevance and then by number of times they were reported for pattern specification process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108129 GDNF Regulation of Gene_expression of GRHL3 1 0.21 0.39 1.71
2 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
3 INT88449 Uncx Positive_regulation of Penk 1 0.12 0 1.27
4 INT280949 Binding of Fst and Inhbe 3 0.01 2.51 1.15
5 INT270053 HOXD12 Positive_regulation of Gene_expression of GAD1 1 0.03 0.68 1.12
6 INT270054 HOXD12 Positive_regulation of Gene_expression of SFTPA1 1 0.01 0.68 1.12
7 INT88446 Uncx Positive_regulation of Th 1 0.13 0 1.1
8 INT167819 IFNA1 Positive_regulation of Fst 1 0.39 0 1.07
9 INT146897 Binding of Fst and OR13H1 1 0.01 0 1.05
10 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
11 INT95791 Binding of SSTR1 and GRHL3 1 0.38 0.57 0.99
12 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
13 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
14 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
15 INT149390 Foxm1 Positive_regulation of Trpa1 1 0.28 0.31 0.94
16 INT6975 Zeb1 Positive_regulation of St8sia1 1 0.03 0.17 0.91
17 INT197470 Binding of Sostdc1 and Hbtq 1 0.00 0.87 0.87
18 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
19 INT108128 GDNF Regulation of Localization of GRHL3 1 0.24 0.18 0.83
20 INT257895 Positive_regulation of Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83
21 INT257896 Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83
22 INT104831 Binding of GLI2 and NFKB1 1 0.08 0 0.8
23 INT64067 Tp63 Negative_regulation of Localization of Gh1 1 0.08 0.07 0.76
24 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
25 INT64070 Tp63 Regulation of Ghrh 1 0.04 0.06 0.69
26 INT64068 Tp63 Regulation of Fdft1 1 0.00 0.06 0.69
27 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
28 INT137102 Fst Regulation of Sec22b 1 0.07 0 0.67
29 INT137101 Fst Regulation of Htr1a 1 0.24 0 0.67
30 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
31 INT139079 Tnip1 Negative_regulation of Ptch1 1 0.20 0.63 0.62
32 INT177979 Binding of STAT3 and FOXI2 1 0.00 1.83 0.61
33 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
34 INT144320 Binding of Fst and Rbm39 1 0.04 0 0.59
35 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57
36 INT308891 Adp Positive_regulation of P2ry13 1 0.15 0.11 0.55
37 INT308895 Adp Positive_regulation of P2ry12 1 0.14 0.11 0.55
38 INT308894 Adp Regulation of P2ry1 1 0.05 0.49 0.53
39 INT138353 Foxm1 Positive_regulation of Phosphorylation of Trpv1 1 0.10 0.31 0.51
40 INT138352 Foxm1 Positive_regulation of Trpa1 1 0.05 0.33 0.51
41 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
42 INT206010 Foxm1 Positive_regulation of Gene_expression of Il18 1 0.03 0.72 0.5
43 INT86088 Foxm1 Positive_regulation of Binding of Crygs 1 0.04 0 0.49
44 INT86089 Foxm1 Regulation of Binding of Crygs 1 0.02 0 0.49
45 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
46 INT155881 Binding of CDX2 and KRAS 1 0.40 1.51 0.47
47 INT308892 Adp Positive_regulation of P2ry1 1 0.11 0.44 0.47
48 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
49 INT343642 Adp Positive_regulation of Localization of Hspg2 1 0.01 0 0.44
50 INT343643 Adp Positive_regulation of Positive_regulation of Hspg2 1 0.01 0 0.43
51 INT292634 IL4 Positive_regulation of Gene_expression of FOXP3 1 0.10 0.42 0.43
52 INT290269 KNG1 Positive_regulation of Binding of MID1 1 0.02 1.06 0.41
53 INT116938 Positive_regulation of GLI2 Positive_regulation of MAPK8 1 0.10 0.07 0.41
54 INT290270 KNG1 Positive_regulation of MID1 1 0.02 1.06 0.41
55 INT116936 Positive_regulation of GLI2 Positive_regulation of JUN 1 0.12 0.07 0.41
56 INT343640 Positive_regulation of Grm5 Positive_regulation of Adp 1 0.01 0 0.4
57 INT278944 ZEB1 Negative_regulation of IL1B 1 0.00 1.09 0.39
58 INT13077 Tac2 Positive_regulation of NKX2-1 1 0.00 0 0.39
59 INT334533 Binding of Foxq1 and Ngf 1 0.05 0.8 0.38
60 INT278960 ZEB1 Negative_regulation of MMP3 1 0.00 1.05 0.38
61 INT278943 ZEB1 Negative_regulation of Gene_expression of MMP3 1 0.00 1.05 0.38
62 INT217028 Adp Negative_regulation of Il12b 1 0.00 0 0.37
63 INT249090 FOXL1 Regulation of Regulation of ICAM1 1 0.12 1.03 0.37
64 INT97790 Foxm1 Negative_regulation of Gene_expression of Nos2 1 0.03 0.16 0.36
65 INT308889 Binding of Idh1 and Adp 1 0.02 0 0.36
66 INT139974 Adp Positive_regulation of Gene_expression of Selp 1 0.00 1.79 0.34
67 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
68 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34
69 INT149897 Ihh Positive_regulation of Mmp14 1 0.03 0.93 0.33
70 INT285565 Positive_regulation of Zeb1 Negative_regulation of IL2 1 0.02 0.62 0.33
71 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
72 INT149895 Ihh Regulation of Localization of Mmp7 1 0.03 0.98 0.33
73 INT285563 Zeb1 Negative_regulation of IL2 1 0.01 0.62 0.33
74 INT149902 Ihh Positive_regulation of SGCG 1 0.45 0.76 0.32
75 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
76 INT258171 Binding of Asap1 and Adp 1 0.04 0 0.31
77 INT140385 Spp1 Negative_regulation of FOXO3 1 0.04 1.29 0.3
78 INT149898 Ihh Regulation of Localization of Mmp14 1 0.03 1.29 0.27
79 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27
80 INT342164 Binding of Csf2 and Nkx2-1 1 0.01 0.52 0.26
81 INT66812 Foxp4 Negative_regulation of POMC 1 0.00 0.42 0.26
82 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
83 INT308893 P2ry1 Positive_regulation of Adp 1 0.12 0 0.25
84 INT212568 Fst Regulation of Gene_expression of Il2 1 0.30 0.07 0.24
85 INT190052 Binding of Cdx2 and Ebp 1 0.08 0.82 0.24
86 INT225118 Foxm1 Positive_regulation of Gene_expression of MMP2 1 0.01 0.34 0.23
87 INT210798 Ihh Positive_regulation of Itgbl1 1 0.34 0 0.23
88 INT88447 Uncx Negative_regulation of Binding of Jun 1 0.07 0 0.22
89 INT104834 Binding of GLI2 and IGKV2OR2-1 1 0.00 0 0.22
90 INT225117 Foxm1 Regulation of Gene_expression of FN1 1 0.01 0.4 0.22
91 INT242245 Binding of P2ry1 and Adp 1 0.00 0.31 0.21
92 INT52459 Binding of SUCLA2 and HEY2 1 0.01 0.09 0.21
93 INT242244 Binding of P2ry12 and Adp 1 0.00 0.31 0.21
94 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
95 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2
96 INT93648 Adp Positive_regulation of ITGA2B 1 0.00 0.79 0.2
97 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
98 INT343641 Grm5 Positive_regulation of Adp 1 0.01 0 0.19
99 INT322543 Binding of FOXO3 and Cdkn1b 1 0.08 0.84 0.19
100 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19
101 INT217038 Adp Negative_regulation of TNF 1 0.02 0 0.19
102 INT286965 Binding of STAT3 and FOXP3 1 0.27 1.84 0.19
103 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
104 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
105 INT217033 Adp Positive_regulation of Ik 1 0.00 0 0.18
106 INT351088 Negative_regulation of ERBB2 Positive_regulation of FOXO3 1 0.17 0.66 0.18
107 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
108 INT306425 Positive_regulation of Binding of TBX1 and VCF 1 0.02 1.15 0.18
109 INT306261 AKT2 Negative_regulation of Phosphorylation of FOXO1 1 0.25 0.41 0.17
110 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
111 INT88451 Uncx Regulation of Transcription of Penk 1 0.06 0 0.17
112 INT306426 Binding of TBX1 and VCF 1 0.01 1.09 0.17
113 INT302553 Binding of CD8A and MID1 1 0.01 0.38 0.17
114 INT88450 Uncx Regulation of Gene_expression of Th 1 0.06 0 0.17
115 INT88445 Uncx Positive_regulation of Gene_expression of Penk 1 0.10 0 0.17
116 INT86897 Glp2r Regulation of Gene_expression of Cdx1 1 0.20 0 0.17
117 INT86892 Glp2r Regulation of Gene_expression of Cdx2 1 0.38 0 0.17
118 INT86894 Glp2r Regulation of Cdx1 1 0.20 0 0.17
119 INT296081 Binding of FOXP3 and Gtf3a 1 0.00 1.16 0.16
120 INT303939 TRAP Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
121 INT296030 Binding of NFKB1 and FOXP3 1 0.17 1.18 0.16
122 INT303941 CCL2 Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
123 INT210782 Ihh Negative_regulation of Itgbl1 1 0.31 0 0.16
124 INT210804 Ihh Negative_regulation of Timp4 1 0.32 0 0.16
125 INT104837 IGKV2OR2-1 Negative_regulation of GLI2 1 0.00 0 0.15
126 INT240899 Negative_regulation of Ros1 Positive_regulation of Phosphorylation of Foxo1 1 0.14 0.41 0.15
127 INT350719 MIR219-1 Negative_regulation of Foxj3 1 0.01 0.4 0.15
128 INT296082 Binding of Rel and FOXP3 1 0.35 1.14 0.15
129 INT286769 Tusc2 Regulation of Foxm1 1 0.02 1.55 0.15
130 INT306268 CRKL Positive_regulation of RASGRP1 1 0.02 0.54 0.14
131 INT213551 Proc Regulation of Bmp7 1 0.00 0.15 0.14
132 INT306272 CRKL Positive_regulation of JUN 1 0.05 0.54 0.14
133 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13
134 INT334524 Sema3a Regulation of Foxq1 1 0.04 1.61 0.13
135 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
136 INT316190 Apc Negative_regulation of Positive_regulation of Mapk1 1 0.33 0.66 0.12
137 INT217027 Adp Positive_regulation of Gene_expression of Il23a 1 0.00 0 0.12
138 INT280484 Bdnf Positive_regulation of Gene_expression of Lhx1 1 0.48 1.49 0.11
139 INT309371 Lhx1 Positive_regulation of Gene_expression of Pax2 1 0.08 0.07 0.11
140 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11
141 INT265919 Binding of PLEK and Adp 1 0.01 0.38 0.11
142 INT286969 IL2 Regulation of Gene_expression of FOXP3 1 0.04 1.05 0.1
143 INT316823 Sparc Positive_regulation of Phosphorylation of Smad2 1 0.44 0.49 0.1
144 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
145 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
146 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
147 INT165161 Ihh Positive_regulation of Sostdc1 1 0.58 0.07 0.09
148 INT165160 Regulation of Ihh Positive_regulation of Sostdc1 1 0.23 0.07 0.09
149 INT86893 Glp2r Positive_regulation of Gene_expression of Cdx1 1 0.18 0 0.09
150 INT165158 Positive_regulation of Ihh Positive_regulation of Sostdc1 1 0.42 0.07 0.09
151 INT129624 Bmp7 Positive_regulation of Gene_expression of Id2 1 0.26 0.31 0.08
152 INT270457 Binding of Ptch1 and Gli1 1 0.02 1.3 0.08
153 INT210788 Ihh Negative_regulation of Coro1a 1 0.02 0 0.08
154 INT213418 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of VCAM1 1 0.29 0.15 0.08
155 INT129623 Bmp7 Positive_regulation of Gene_expression of Id3 1 0.37 0.31 0.08
156 INT129625 Id2 Positive_regulation of Gene_expression of Bmp7 1 0.24 0.31 0.08
157 INT222511 Il1a Positive_regulation of Gene_expression of Fst 1 0.01 0.32 0.08
158 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
159 INT238625 Mef2c Regulation of Gene_expression of Syngap1 1 0.10 0.16 0.08
160 INT129622 Id3 Positive_regulation of Gene_expression of Bmp7 1 0.25 0.31 0.08
161 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08
162 INT210790 Ihh Negative_regulation of Cdkn1c 1 0.30 0 0.08
163 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
164 INT240897 Akt1 Negative_regulation of Positive_regulation of Foxo1 1 0.21 0.22 0.08
165 INT210787 Ihh Negative_regulation of Nr3c1 1 0.33 0 0.08
166 INT270197 Binding of Apc and Cd86 1 0.02 0.58 0.08
167 INT296039 Binding of FOXP3 and IL17RB 1 0.01 0.63 0.08
168 INT296034 FOXP3 Negative_regulation of Gene_expression of IL7R 1 0.10 0.63 0.08
169 INT213419 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of HGF 1 0.25 0.15 0.08
170 INT270198 Binding of Apc and Cd80 1 0.02 0.58 0.08
171 INT350708 Foxp3 Regulation of Socs1 1 0.08 0.21 0.07
172 INT129627 Bmp7 Positive_regulation of Id2 1 0.24 0.25 0.07
173 INT265883 IGF1 Positive_regulation of Transcription of FOXO1 1 0.17 1.14 0.07
174 INT351422 Mfng Negative_regulation of Jag1 1 0.06 1.29 0.07
175 INT129626 Bmp7 Positive_regulation of Id3 1 0.25 0.25 0.07
176 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
177 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
178 INT265893 BAD Regulation of FOXO1 1 0.03 1.08 0.06
179 INT222431 Tlr4 Positive_regulation of Gene_expression of Fst 1 0.01 0.29 0.06
180 INT262190 Foxo1 Positive_regulation of Pck1 1 0.04 0.15 0.06
181 INT201973 Bmp7 Positive_regulation of ap 1 0.00 0.18 0.06
182 INT300310 Akt1 Regulation of Foxo3 1 0.21 1.5 0.06
183 INT118462 BMP7 Regulation of Bmp7 1 0.19 0 0.06
184 INT222463 Inhba Positive_regulation of Gene_expression of Fst 1 0.01 0 0.05
185 INT222520 Mzb1 Positive_regulation of Gene_expression of Fst 1 0.04 0 0.05
186 INT222476 Gnrh1 Negative_regulation of Gene_expression of Fst 1 0.04 0 0.05
187 INT353284 Prdx2 Negative_regulation of Gene_expression of Smad2 1 0.16 0.07 0.05
188 INT176095 Binding of Apc and EC 1 0.04 0.51 0.05
189 INT299457 Foxl2 Positive_regulation of Gnrhr 1 0.42 0.56 0.05
190 INT84196 Binding of MAOA and FOXI2 1 0.03 0 0.05
191 INT343538 TGFB1 Positive_regulation of Gene_expression of GLI2 1 0.08 0.2 0.05
192 INT120574 Binding of Apc and Egfr 1 0.27 1.02 0.05
193 INT299460 Foxl2 Positive_regulation of Tpr 1 0.01 0.56 0.05
194 INT262757 SMO Positive_regulation of Regulation of GLI1 1 0.34 0.6 0.04
195 INT249922 Binding of Pah and Asph 1 0.06 0.4 0.04
196 INT233850 Zeb1 Positive_regulation of Itk 1 0.04 0.58 0.04
197 INT249921 Binding of Hif1a and Asph 1 0.05 0.41 0.04
198 INT280817 Binding of Cdx1 and Crh 1 0.02 0.21 0.04
199 INT233848 Zeb1 Positive_regulation of Snai1 1 0.07 0.58 0.04
200 INT233853 Zeb1 Positive_regulation of Snai2 1 0.09 0.58 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported for pattern specification process. They are ordered first by their pain relevance and then by number of times they were reported in pattern specification process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65277 Negative_regulation of Fst 20 0.43 4.61 11.83
2 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64
3 INT95794 Gene_expression of GRHL3 9 0.68 5.57 9.9
4 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12
5 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
6 INT70572 Gene_expression of Fst 33 0.78 5.22 8.24
7 INT127961 Transcription of GRHL3 1 0.45 4.34 8.17
8 INT1965 Gene_expression of Adp 15 0.20 5.05 8.03
9 INT1963 Positive_regulation of Adp 12 0.11 3.73 7.6
10 INT60931 Negative_regulation of Fst 15 0.57 5.44 7.21
11 INT50337 Negative_regulation of Foxm1 24 0.43 11.12 6.48
12 INT86060 Positive_regulation of Fst 13 0.64 3.04 6.33
13 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
14 INT128406 Gene_expression of Pax1 11 0.60 7.18 5.91
15 INT55513 Binding of Foxm1 19 0.37 2.37 5.54
16 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36
17 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
18 INT83735 Gene_expression of Foxm1 41 0.77 22.9 5.07
19 INT65276 Gene_expression of Fst 12 0.65 4.99 5.05
20 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
21 INT197458 Positive_regulation of Sostdc1 11 0.01 3.02 4.87
22 INT127964 Regulation of Transcription of GRHL3 1 0.28 2.54 4.84
23 INT28269 Negative_regulation of Adp 18 0.36 5.98 4.74
24 INT165058 Negative_regulation of MID1 14 0.37 10.82 4.67
25 INT197459 Gene_expression of Sostdc1 10 0.01 1.04 4.11
26 INT64170 Gene_expression of GLI2 31 0.46 14.96 3.99
27 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
28 INT270065 Positive_regulation of HOXD12 1 0.05 1.11 3.86
29 INT127962 Positive_regulation of GRHL3 3 0.32 2.67 3.69
30 INT22410 Regulation of Adp 7 0.19 3.24 3.56
31 INT127963 Positive_regulation of Gene_expression of GRHL3 1 0.44 1.85 3.4
32 INT12844 Binding of TP63 15 0.47 10.57 3.38
33 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3
34 INT137532 Negative_regulation of HEY2 1 0.31 1.69 3.18
35 INT165057 Binding of MID1 7 0.32 4.13 3.12
36 INT33237 Regulation of Fst 10 0.39 1.3 3
37 INT28271 Localization of Adp 20 0.25 4.92 2.89
38 INT132773 Negative_regulation of Acvr2b 3 0.41 1.55 2.87
39 INT50335 Positive_regulation of Foxm1 20 0.69 5.11 2.81
40 INT188344 Positive_regulation of Gene_expression of Foxp3 10 0.36 5.97 2.56
41 INT127113 Positive_regulation of Phosphorylation of Smad2 1 0.68 2.38 2.51
42 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
43 INT113203 Regulation of Foxm1 8 0.34 7.5 2.36
44 INT165059 Gene_expression of MID1 11 0.58 3.68 2.31
45 INT194504 Gene_expression of Smad2 27 0.65 7.45 2.25
46 INT108131 Localization of GRHL3 3 0.73 1.03 2.18
47 INT163580 Positive_regulation of Fst 4 0.19 2.85 2.17
48 INT249754 Phosphorylation of Adp 2 0.10 1.2 2.1
49 INT13075 Binding of NKX2-1 6 0.05 0.12 2.08
50 INT93764 Binding of GRHL3 3 0.36 1.79 2.07
51 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
52 INT158442 Gene_expression of Nkx2-1 21 0.59 8.47 1.99
53 INT138316 Regulation of Fst 5 0.44 1.15 1.99
54 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98
55 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
56 INT32190 Binding of Adp 9 0.12 2.42 1.91
57 INT24850 Regulation of GRHL3 4 0.45 0.32 1.9
58 INT90026 Gene_expression of FOXI2 5 0.03 0.98 1.79
59 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
60 INT90926 Positive_regulation of GLI2 12 0.45 4.99 1.74
61 INT221426 Positive_regulation of Gene_expression of FOXP3 9 0.48 5.98 1.72
62 INT3818 Regulation of Apc 13 0.39 12.52 1.68
63 INT280933 Binding of Fst 4 0.12 3.53 1.63
64 INT113985 Positive_regulation of TP63 9 0.50 8.79 1.62
65 INT234116 Positive_regulation of MID1 9 0.03 3.78 1.61
66 INT193823 Positive_regulation of Gene_expression of TP63 7 0.18 7.74 1.57
67 INT244735 Gene_expression of Ascl1 12 0.58 2.48 1.54
68 INT127115 Regulation of Phosphorylation of Smad2 1 0.60 1.74 1.53
69 INT167872 Negative_regulation of Gene_expression of Foxp3 8 0.50 4.14 1.46
70 INT140245 Binding of Gli3 3 0.36 2.65 1.46
71 INT255251 Negative_regulation of Smad2 12 0.32 5.69 1.44
72 INT113151 Positive_regulation of Ptch1 7 0.64 3.8 1.41
73 INT165538 Binding of Bmp7 5 0.37 1.87 1.39
74 INT220177 Binding of Apc 21 0.37 15.34 1.37
75 INT129619 Phosphorylation of Smad2 34 0.61 11.6 1.34
76 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
77 INT139077 Negative_regulation of Ptch1 5 0.56 5.22 1.29
78 INT104839 Negative_regulation of GLI2 8 0.35 2.7 1.24
79 INT216628 Protein_catabolism of Adp 5 0.21 1.98 1.22
80 INT84130 Gene_expression of Foxo1 1 0.26 0.97 1.22
81 INT183068 Gene_expression of SMO 2 0.17 0.27 1.2
82 INT239028 Negative_regulation of Foxo4 1 0.42 2.75 1.16
83 INT140983 Gene_expression of Ihh 7 0.78 2.06 1.15
84 INT229562 Negative_regulation of Foxp3 6 0.36 3.7 1.14
85 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
86 INT93765 Negative_regulation of Binding of GRHL3 1 0.41 0.43 1.14
87 INT278117 Negative_regulation of TP63 5 0.32 3.38 1.13
88 INT78266 Localization of NKX2-1 2 0.73 0.16 1.12
89 INT165056 Regulation of Gene_expression of MID1 2 0.39 0.93 1.1
90 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
91 INT138349 Phosphorylation of Foxm1 1 0.10 0.9 1.05
92 INT86889 Gene_expression of Cdx2 8 0.60 4.23 1.02
93 INT15040 Gene_expression of NKX2-1 8 0.65 3.95 1.02
94 INT119674 Localization of GLI2 6 0.52 2.84 0.99
95 INT182322 Negative_regulation of Gene_expression of GLI2 6 0.11 2.37 0.98
96 INT281594 Phosphorylation of Foxo3 3 0.67 21.16 0.95
97 INT218696 Negative_regulation of Phosphorylation of Smad2 3 0.42 4.36 0.92
98 INT280942 Localization of Fst 2 0.22 2.13 0.91
99 INT257893 Negative_regulation of Positive_regulation of Sostdc1 1 0.01 0 0.9
100 INT242134 Localization of Apc 8 0.74 4.83 0.88
101 INT64173 Regulation of Gene_expression of GLI2 4 0.37 2.89 0.88
102 INT13074 Positive_regulation of NKX2-1 4 0.19 0.86 0.87
103 INT289474 Regulation of GLI2 2 0.06 1.08 0.87
104 INT285477 Positive_regulation of Zeb1 2 0.17 0.86 0.86
105 INT90054 Regulation of Rax 3 0.25 0.8 0.85
106 INT135299 Binding of PTCH1 10 0.48 12.16 0.84
107 INT72710 Negative_regulation of Negative_regulation of Foxm1 3 0.10 0.55 0.84
108 INT221427 Positive_regulation of FOXP3 6 0.45 2.74 0.83
109 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82
110 INT157492 Transcription of Foxp3 4 0.61 1.69 0.81
111 INT267095 Regulation of Gene_expression of Smad2 3 0.44 1.77 0.8
112 INT270447 Binding of Smo 2 0.07 2.61 0.78
113 INT270059 Negative_regulation of Gene_expression of HOXD12 1 0.04 0.48 0.77
114 INT150251 Transcription of FOXP3 7 0.61 0.43 0.76
115 INT44293 Regulation of TP63 6 0.24 2.88 0.76
116 INT270061 Gene_expression of HOXD12 1 0.06 0.48 0.76
117 INT142416 Binding of Ptch1 6 0.34 4.92 0.74
118 INT265318 Negative_regulation of Gene_expression of Smad2 8 0.26 2.16 0.72
119 INT104840 Binding of GLI2 6 0.08 1.89 0.72
120 INT15039 Negative_regulation of NKX2-1 3 0.21 0 0.72
121 INT217098 Gene_expression of Hoxa2 1 0.77 2.23 0.72
122 INT226179 Phosphorylation of Foxo1 15 0.68 3.14 0.7
123 INT221428 Negative_regulation of Negative_regulation of FOXP3 1 0.35 1.97 0.7
124 INT269896 Positive_regulation of Gene_expression of Smad2 9 0.40 2.15 0.69
125 INT68560 Regulation of Gli3 3 0.18 1.51 0.68
126 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67
127 INT156967 Localization of Fst 2 0.66 0.1 0.66
128 INT203749 Binding of FOXM1 10 0.31 6.1 0.64
129 INT308888 Regulation of Negative_regulation of Adp 2 0.06 1.09 0.64
130 INT156968 Negative_regulation of Localization of Fst 1 0.37 0.1 0.64
131 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
132 INT297286 Positive_regulation of Foxp3 7 0.58 3.05 0.63
133 INT201627 Gene_expression of Foxo4 3 0.65 1.92 0.63
134 INT148385 Positive_regulation of HEY2 1 0.38 1.09 0.62
135 INT100294 Positive_regulation of Gene_expression of Bmp7 8 0.46 5.41 0.61
136 INT201640 Phosphorylation of Foxo4 4 0.80 3.55 0.61
137 INT239019 Negative_regulation of Phosphorylation of Foxo4 2 0.42 2.38 0.61
138 INT205957 Negative_regulation of Smo 4 0.08 2.57 0.6
139 INT165156 Gene_expression of Sostdc1 4 0.59 2.52 0.6
140 INT311777 Regulation of MID1 3 0.16 4.43 0.6
141 INT143958 Negative_regulation of Gene_expression of Cdx2 1 0.13 0.1 0.58
142 INT249764 Regulation of Binding of Foxm1 1 0.39 0.19 0.58
143 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56
144 INT140984 Regulation of Ihh 5 0.54 2.81 0.56
145 INT206006 Negative_regulation of Gene_expression of Foxm1 4 0.43 2.63 0.56
146 INT12653 Localization of Foxp4 2 0.80 0 0.56
147 INT349703 Positive_regulation of Transcription of Fst 1 0.46 0.14 0.53
148 INT349725 Transcription of Fst 1 0.63 0.13 0.53
149 INT165537 Negative_regulation of Bmp7 2 0.43 0.55 0.52
150 INT135062 Transcription of Gli3 1 0.05 0 0.52
151 INT86087 Negative_regulation of Binding of Foxm1 1 0.28 0 0.52
152 INT156254 Gene_expression of Six1 7 0.67 1.52 0.51
153 INT158889 Gene_expression of Smad2 5 0.65 1.25 0.51
154 INT206009 Transcription of Foxm1 2 0.68 1.49 0.51
155 INT306741 Positive_regulation of Positive_regulation of TP63 2 0.05 1.16 0.49
156 INT28268 Negative_regulation of Localization of Adp 4 0.08 0.94 0.48
157 INT278121 Negative_regulation of Negative_regulation of TP63 1 0.03 0 0.48
158 INT157490 Regulation of Gene_expression of Foxp3 5 0.37 2.4 0.47
159 INT129620 Regulation of Gene_expression of Bmp7 3 0.42 3.2 0.47
160 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46
161 INT206484 Localization of Shh 2 0.75 1.14 0.46
162 INT6808 Localization of Zeb1 2 0.18 0 0.45
163 INT218293 Gene_expression of Acvr2b 14 0.76 4.22 0.44
164 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
165 INT302554 Localization of MID1 3 0.19 0.67 0.44
166 INT122525 Regulation of FOXO1 3 0.58 1.76 0.44
167 INT265915 Negative_regulation of Binding of Adp 2 0.01 0.65 0.44
168 INT22408 Positive_regulation of Regulation of Adp 1 0.04 0.54 0.44
169 INT159221 Negative_regulation of TBX1 4 0.41 4.22 0.43
170 INT88453 Gene_expression of Uncx 5 0.33 2.48 0.42
171 INT133315 Gene_expression of ZEB1 4 0.59 2.93 0.42
172 INT152151 Regulation of Gene_expression of Apc 4 0.44 3.87 0.42
173 INT188345 Regulation of Foxp3 3 0.18 1.59 0.42
174 INT281589 Localization of Foxo3 2 0.61 7.91 0.42
175 INT265898 Transcription of FOXO1 2 0.50 2.29 0.41
176 INT65606 Binding of TBX1 2 0.30 3.13 0.41
177 INT118460 Binding of Bmp7 3 0.46 1.3 0.4
178 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
179 INT50336 Negative_regulation of Positive_regulation of Foxm1 1 0.30 0 0.38
180 INT249785 Positive_regulation of Gene_expression of Foxm1 13 0.69 4.71 0.36
181 INT317694 Negative_regulation of Localization of Fst 1 0.12 0.79 0.36
182 INT220170 Regulation of Positive_regulation of Apc 1 0.10 0.46 0.35
183 INT260115 Regulation of FOXP3 3 0.29 0.75 0.34
184 INT288541 Negative_regulation of Gene_expression of Fst 2 0.23 1.18 0.34
185 INT178001 Regulation of Negative_regulation of FOXI2 1 0.00 1.01 0.34
186 INT177996 Negative_regulation of FOXI2 1 0.01 1.01 0.34
187 INT166716 Negative_regulation of Ihh 3 0.43 0.67 0.33
188 INT285492 Transcription of Zeb1 1 0.17 0.61 0.33
189 INT285469 Positive_regulation of Transcription of Zeb1 1 0.12 0.61 0.33
190 INT225667 Transcription of Apc 3 0.52 3.73 0.32
191 INT207073 Localization of Pax1 2 0.63 0.87 0.32
192 INT310379 Negative_regulation of FOXO3 2 0.42 1.28 0.32
193 INT274626 Positive_regulation of Positive_regulation of GRHL3 1 0.22 0.67 0.32
194 INT349714 Binding of Fst 1 0.34 0.19 0.32
195 INT249100 Positive_regulation of FOXL1 1 0.55 0.99 0.32
196 INT196032 Positive_regulation of Gene_expression of Bmp7 10 0.17 1.31 0.31
197 INT177995 Phosphorylation of FOXI2 1 0.01 0.93 0.31
198 INT230390 Binding of Sostdc1 1 0.04 0.96 0.31
199 INT196024 Gene_expression of Bmp7 20 0.26 1.88 0.3
200 INT129908 Positive_regulation of Smad2 5 0.45 2.13 0.3
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