GO:0007399

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Name nervous system development
Categary Process
Go Slim No
Go Link GO:0007399
Unique Molecular Interactions 4410
Total Molecular Interactions 6298
Total Single Events 60187
Pain Genes Associated 303

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nervous system development. They are ordered first by their pain relevance and then by number of times they were reported for nervous system development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
2 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
3 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
4 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
5 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
6 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
7 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
8 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
9 INT269444 Binding of RAB5A and HHIP 1 0.04 0 5.79
10 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
11 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
12 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49
13 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
14 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
15 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
16 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
17 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
18 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
19 INT64883 Ptger2 Positive_regulation of Ina 1 0.03 1.26 3.64
20 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
21 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
22 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
23 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
24 INT289979 Binding of Helt and Negative_regulation of Maoa 1 0.00 0.17 3.14
25 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
26 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
27 INT152699 Bdnf Positive_regulation of Ltp 5 0.05 1.22 2.95
28 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
29 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84
30 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
31 INT229497 Binding of Vim and Ndel1 1 0.33 3.5 2.81
32 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
33 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
34 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
35 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
36 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
37 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67
38 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
39 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
40 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
41 INT340117 Binding of Bdnf and Pain1 1 0.01 2.48 2.55
42 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
43 INT14687 Binding of Penk and Ppt1 1 0.41 0 2.46
44 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
45 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
46 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37
47 INT284860 Binding of Pdzd2 and Nav1 9 0.29 2.33 2.34
48 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
49 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
50 INT128778 Binding of Mcam and Nav1 1 0.03 0.51 2.28
51 INT128777 Binding of Cntn1 and Nav1 1 0.48 0.51 2.28
52 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
53 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 0.69 0.5 2.18
54 INT142527 Binding of Slc1a2 and Slc1a3 2 0.31 0.12 2.13
55 INT344386 Efnb1 Positive_regulation of Phosphorylation of Ephb2 1 0.15 2.85 2.13
56 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
57 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
58 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
59 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
60 INT334532 Sema3a Negative_regulation of Gene_expression of Nrp1 1 0.19 7.58 2
61 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98
62 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
63 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
64 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
65 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
66 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8
67 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
68 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
69 INT334345 Binding of GRP and Helt 1 0.02 0 1.79
70 INT122964 FSCN1 Positive_regulation of Bdnf 1 0.01 1.14 1.79
71 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78
72 INT167319 Binding of OPRM1 and PCSK2 1 0.22 0.63 1.77
73 INT23392 Gal Regulation of Trpv1 1 0.05 0.33 1.77
74 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76
75 INT190981 Binding of Npy and Scn2a1 1 0.10 0 1.75
76 INT142899 Chn1 Negative_regulation of Positive_regulation of NOS1 1 0.01 1.07 1.75
77 INT142073 Binding of Helt and Nrm 1 0.00 0 1.74
78 INT129953 Oprd1 Regulation of Cspg5 1 0.17 0.15 1.74
79 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
80 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
81 INT108129 GDNF Regulation of Gene_expression of GRHL3 1 0.21 0.39 1.71
82 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
83 INT119413 SEMA6A Positive_regulation of TNFRSF11A 1 0.10 2.48 1.7
84 INT30134 Binding of TPP1 and S100A9 1 0.13 0.74 1.69
85 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
86 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
87 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67
88 INT291578 Negative_regulation of Pde12 Positive_regulation of Pde5a 1 0.03 1.11 1.67
89 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
90 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
91 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
92 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
93 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
94 INT317184 BMS1 Regulation of Gene_expression of NAV1 1 0.03 1.94 1.62
95 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
96 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
97 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
98 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54
99 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54
100 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
101 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5
102 INT64628 Binding of Oxt and Gal 2 0.29 0.29 1.49
103 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
104 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48
105 INT334633 Binding of Cntnap1 and Nav1 1 0.10 1.36 1.48
106 INT14375 Gal Positive_regulation of Localization of Prl 1 0.77 0 1.48
107 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48
108 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
109 INT165450 Gal Regulation of Ceacam3 1 0.41 0.06 1.47
110 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
111 INT144452 Binding of GPM6A and GPM6B 1 0.28 0 1.46
112 INT291583 GUCY2C Regulation of Pde5a 1 0.00 1.12 1.45
113 INT6976 Helt Regulation of Gene_expression of St8sia1 1 0.00 0.07 1.45
114 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
115 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
116 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44
117 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
118 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
119 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
120 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
121 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42
122 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
123 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42
124 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41
125 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
126 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4
127 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
128 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
129 INT108583 Binding of Vip and Fos 1 0.36 0 1.39
130 INT167528 Ppt1 Negative_regulation of Gene_expression of Tac4 1 0.06 0.49 1.39
131 INT131949 ANTXR1 Positive_regulation of NAV1 1 0.03 0.23 1.38
132 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 1 0.26 0.49 1.38
133 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
134 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
135 INT229496 Binding of Ndel1 and Gopc 1 0.08 2.05 1.36
136 INT326194 Bdnf Regulation of Slc12a5 1 0.05 0.85 1.35
137 INT15277 Binding of Tac1 and Gal 1 0.39 0.19 1.35
138 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
139 INT250934 Binding of BDNF and NGF 3 0.39 0.62 1.34
140 INT180802 Gdnf Positive_regulation of Sorbs1 1 0.02 0.98 1.34
141 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
142 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
143 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32
144 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
145 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
146 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
147 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
148 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
149 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
150 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3
151 INT96707 Ntf3 Positive_regulation of Localization of SST 1 0.01 0 1.3
152 INT96708 Bdnf Positive_regulation of Localization of SST 1 0.01 0 1.3
153 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29
154 INT66428 Dcc Positive_regulation of Fos 2 0.05 0.39 1.29
155 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
156 INT121802 DEAF1 Negative_regulation of HTR1A 1 0.46 0.88 1.29
157 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27
158 INT343949 SERPINE2 Positive_regulation of Positive_regulation of Slco1c1 1 0.00 0.59 1.27
159 INT88449 Uncx Positive_regulation of Penk 1 0.12 0 1.27
160 INT159655 Binding of BDNF and INSRR 2 0.00 1.25 1.26
161 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
162 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 1 0.47 0.88 1.26
163 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
164 INT110542 SIGMAR1 Regulation of OPRM1 1 0.04 0.33 1.25
165 INT110543 SIGMAR1 Regulation of Gene_expression of OPRM1 1 0.04 0.33 1.25
166 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25
167 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
168 INT305408 Binding of KCNMA1 and ST8SIA2 1 0.01 0.09 1.24
169 INT50386 Bdnf Regulation of Npy 1 0.21 0.47 1.24
170 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
171 INT71443 CSAD Positive_regulation of Gene_expression of Fos 1 0.58 0.81 1.23
172 INT50385 Bdnf Positive_regulation of Pomc 1 0.22 0.47 1.23
173 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
174 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
175 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
176 INT197231 Grik1 Regulation of Gabrg1 1 0.19 0.13 1.22
177 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
178 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22
179 INT298260 Binding of Runx3 and Pou4f1 1 0.52 2.08 1.22
180 INT62368 Gal Positive_regulation of Localization of LH 3 0.36 0 1.2
181 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 0.06 2.38 1.2
182 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
183 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2
184 INT109380 Binding of Adarb1 and Fos 1 0.02 0.38 1.19
185 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
186 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18
187 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
188 INT220752 Negative_regulation of EGF Regulation of NAV1 1 0.26 0 1.18
189 INT73075 Adarb1 Regulation of Fos 1 0.01 0.07 1.18
190 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18
191 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
192 INT148437 Binding of Bdnf and Ngf 2 0.32 1.9 1.17
193 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17
194 INT220748 EGF Regulation of NAV1 1 0.28 0 1.17
195 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
196 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
197 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 0.34 0.14 1.16
198 INT76256 Binding of Slc6a3 and Sigmar1 1 0.20 0 1.16
199 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
200 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14

Single Events

The table below shows the top 100 pain related interactions that have been reported for nervous system development. They are ordered first by their pain relevance and then by number of times they were reported in nervous system development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
3 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
4 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
5 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1
6 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75
7 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54
8 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46
9 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
10 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
11 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
12 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82
13 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05
14 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68
15 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01
16 INT74826 Gene_expression of Slc1a2 131 0.78 61.83 100.84
17 INT5587 Regulation of Fos 191 0.62 40.81 99.7
18 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31
19 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
20 INT67682 Localization of Bdnf 204 0.81 72.36 88.92
21 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12
22 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
23 INT8650 Gene_expression of Gal 152 0.78 61.97 81.72
24 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
25 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
26 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5
27 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
28 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
29 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
30 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03
31 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
32 INT129303 Positive_regulation of NAV1 54 0.70 36.92 57.45
33 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06
34 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
35 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
36 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
37 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6
38 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
39 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24
40 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81
41 INT74827 Positive_regulation of Gene_expression of Slc1a2 52 0.70 26.54 50.63
42 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
43 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33
44 INT51163 Gene_expression of Gal 119 0.78 67.48 49.23
45 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
46 INT111051 Negative_regulation of Nav1 64 0.59 25.51 47.27
47 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
48 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55
49 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68
50 INT60388 Gene_expression of Helt 90 0.07 19.18 41.72
51 INT16261 Transcription of Bdnf 101 0.72 49.41 40.64
52 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
53 INT103261 Positive_regulation of Nav1 68 0.70 24.25 39.27
54 INT116321 Regulation of Nav1 38 0.62 26.62 37.97
55 INT5039 Positive_regulation of Gal 67 0.68 27.97 37.36
56 INT131413 Positive_regulation of Gene_expression of NAV1 35 0.70 17.5 36.83
57 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
58 INT111052 Positive_regulation of Gene_expression of Nav1 44 0.70 18.98 35.28
59 INT103262 Localization of Nav1 53 0.81 19.23 34.44
60 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
61 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
62 INT6053 Transcription of Fos 107 0.72 20.97 31.88
63 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
64 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
65 INT48890 Gene_expression of Gdnf 91 0.77 28.62 31.49
66 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
67 INT6058 Localization of Fos 73 0.81 16.7 30.84
68 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77
69 INT11796 Positive_regulation of Helt 52 0.31 11.7 29.22
70 INT4868 Gene_expression of GAL 75 0.78 22.23 29.02
71 INT5440 Negative_regulation of Ina 85 0.58 10.52 28.98
72 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78
73 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5
74 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99
75 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
76 INT14575 Positive_regulation of Ppt1 60 0.70 9.97 27.4
77 INT123035 Gene_expression of Ephb1 38 0.78 28.84 27.32
78 INT5923 Negative_regulation of Rtn4 50 0.36 24.19 27.2
79 INT47685 Positive_regulation of Positive_regulation of Bdnf 32 0.70 20.05 27.03
80 INT56053 Negative_regulation of Bdnf 77 0.58 64.4 26.83
81 INT20585 Gene_expression of Gfra1 39 0.77 26.94 26.69
82 INT123419 Binding of NAV1 37 0.48 7.09 26.43
83 INT5378 Regulation of Gene_expression of Fos 47 0.60 14.47 26.41
84 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
85 INT136268 Localization of NAV1 22 0.75 2.84 26.23
86 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95
87 INT116226 Regulation of NAV1 20 0.51 14.32 25.61
88 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
89 INT140413 Gene_expression of AQP4 113 0.78 139.25 25.53
90 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
91 INT77793 Positive_regulation of Gdnf 54 0.70 23.76 25.08
92 INT256285 Gene_expression of Efnb1 32 0.70 36.25 24.73
93 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
94 INT10240 Gene_expression of Gap43 58 0.78 22.11 24.45
95 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
96 INT96557 Binding of Bdnf 46 0.47 21.74 24.26
97 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
98 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
99 INT20003 Gene_expression of Scn2a1 125 0.71 8.78 23.94
100 INT99539 Positive_regulation of Slc1a2 25 0.67 5.46 23.38
101 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
102 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
103 INT113925 Localization of Bdnf 59 0.79 24.03 22.76
104 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24
105 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05
106 INT4890 Gene_expression of Ppt1 51 0.77 8.93 21.83
107 INT5586 Binding of Fos 47 0.48 12.7 21.33
108 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
109 INT5040 Regulation of Gal 42 0.60 12.72 21.18
110 INT4894 Transcription of Ppt1 34 0.67 5.93 21.06
111 INT93485 Negative_regulation of Slc1a2 27 0.59 10.65 20.9
112 INT99237 Gene_expression of Ntrk3 84 0.77 38.68 20.77
113 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75
114 INT102203 Transcription of Bdnf 35 0.71 18.26 20.59
115 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
116 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09
117 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
118 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59
119 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
120 INT124670 Gene_expression of Grik1 53 0.77 4.83 19.13
121 INT5099 Localization of Gal 46 0.81 10.66 18.93
122 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
123 INT56239 Positive_regulation of Rtn4 20 0.26 14.05 18.8
124 INT14306 Positive_regulation of Gal 36 0.70 21.66 18.51
125 INT103469 Positive_regulation of Gene_expression of BDNF 59 0.67 24.39 18.36
126 INT11275 Regulation of Fos 37 0.60 5.79 18.18
127 INT82531 Positive_regulation of Gene_expression of Gal 41 0.69 28.67 18.04
128 INT13244 Binding of Helt 30 0.31 4.56 18.01
129 INT96532 Negative_regulation of Gene_expression of Slc1a2 24 0.59 14.22 17.91
130 INT5922 Gene_expression of Rtn4 27 0.48 12.7 17.86
131 INT92733 Negative_regulation of Ephb1 19 0.51 8.56 17.72
132 INT106556 Negative_regulation of Gene_expression of Bdnf 42 0.59 34.71 17.64
133 INT8526 Negative_regulation of Positive_regulation of Fos 26 0.59 5.99 17.52
134 INT102903 Regulation of Gene_expression of Bdnf 35 0.62 20.1 17.42
135 INT98110 Regulation of Gene_expression of Slc1a2 16 0.62 11.76 17.31
136 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29
137 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23
138 INT111050 Negative_regulation of Gene_expression of Nav1 23 0.58 5.97 17.06
139 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
140 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
141 INT109110 Positive_regulation of Pde5a 29 0.63 11.16 16.65
142 INT69203 Positive_regulation of Ntf3 43 0.66 19.16 16.49
143 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
144 INT256282 Gene_expression of Efnb2 3 0.76 17.61 16.41
145 INT197210 Positive_regulation of Grik1 24 0.69 3.15 16.24
146 INT4866 Positive_regulation of GAL 32 0.67 13.02 16.16
147 INT113384 Regulation of Gene_expression of Nav1 20 0.62 8.57 16.15
148 INT96299 Positive_regulation of Localization of Bdnf 35 0.70 15.67 16.09
149 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95
150 INT97871 Gene_expression of Ntf3 47 0.78 25.9 15.94
151 INT114507 Negative_regulation of Gene_expression of NAV1 17 0.43 7.24 15.93
152 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
153 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
154 INT12837 Binding of SIGMAR1 57 0.48 5.31 15.49
155 INT112207 Binding of Nav1 27 0.47 7.1 15.43
156 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12
157 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
158 INT163479 Binding of Bdnf 36 0.48 25.77 14.83
159 INT6163 Negative_regulation of INA 39 0.43 2.9 14.8
160 INT11795 Negative_regulation of Helt 33 0.28 6.51 14.76
161 INT8794 Negative_regulation of Ppt1 35 0.57 6.44 14.52
162 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
163 INT14264 Binding of Gal 39 0.47 5.7 14.48
164 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
165 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
166 INT7587 Localization of GAL 27 0.78 4.79 14.29
167 INT8986 Positive_regulation of Gene_expression of Gal 24 0.67 10.96 14.09
168 INT13118 Positive_regulation of Ina 48 0.69 7.39 13.85
169 INT11996 Gene_expression of Ina 34 0.67 4.8 13.82
170 INT53070 Regulation of Rtn4 15 0.22 9.35 13.77
171 INT50056 Positive_regulation of Dll1 13 0.67 3.16 13.7
172 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
173 INT13572 Localization of Helt 31 0.36 5.85 13.41
174 INT344368 Positive_regulation of Gene_expression of Efnb1 13 0.63 18.39 13.31
175 INT102897 Positive_regulation of Gene_expression of Gdnf 34 0.69 11.13 13.28
176 INT94861 Gene_expression of Pde5a 40 0.69 14.73 13.27
177 INT20715 Binding of Sigmar1 45 0.48 4.03 13.17
178 INT100655 Regulation of BDNF 51 0.60 21.49 13.14
179 INT47692 Negative_regulation of Positive_regulation of Bdnf 18 0.59 9.64 13.14
180 INT65172 Negative_regulation of Ntrk2 35 0.59 9.89 13.08
181 INT75224 Positive_regulation of Gene_expression of Ntf3 23 0.69 11.79 13.08
182 INT16256 Regulation of Ntf3 15 0.49 9.75 13.07
183 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
184 INT15246 Regulation of FOS 32 0.60 15.34 12.94
185 INT10585 Localization of NAGLU 53 0.80 23.32 12.75
186 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
187 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
188 INT56883 Positive_regulation of Dll1 8 0.49 3.49 12.25
189 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
190 INT7611 Positive_regulation of Cspg5 17 0.67 2.97 12.2
191 INT137043 Transcription of NAV1 16 0.72 6.98 12.12
192 INT61706 Regulation of Gene_expression of Gal 17 0.62 10.09 11.96
193 INT16255 Negative_regulation of Ntf3 21 0.51 12.92 11.93
194 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
195 INT56048 Positive_regulation of Transcription of Bdnf 24 0.70 8.33 11.83
196 INT135909 Positive_regulation of Ephb1 11 0.70 8.94 11.78
197 INT5011 Negative_regulation of Gal 30 0.57 9.88 11.49
198 INT6051 Positive_regulation of Transcription of Fos 27 0.69 6.3 11.48
199 INT150285 Positive_regulation of Efnb1 6 0.29 10.22 11.44
200 INT203473 Gene_expression of Pou4f1 69 0.76 25.94 11.36
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