GO:0007442

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Name hindgut morphogenesis
Categary Process
Go Slim No
Go Link GO:0007442
Unique Molecular Interactions 89
Total Molecular Interactions 114
Total Single Events 645
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for hindgut morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for hindgut morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
2 INT104831 Binding of GLI2 and NFKB1 1 0.08 0 0.8
3 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
4 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
5 INT116938 Positive_regulation of GLI2 Positive_regulation of MAPK8 1 0.10 0.07 0.41
6 INT116936 Positive_regulation of GLI2 Positive_regulation of JUN 1 0.12 0.07 0.41
7 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
8 INT104834 Binding of GLI2 and IGKV2OR2-1 1 0.00 0 0.22
9 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
10 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
11 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
12 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
13 INT303939 TRAP Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
14 INT303941 CCL2 Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
15 INT104837 IGKV2OR2-1 Negative_regulation of GLI2 1 0.00 0 0.15
16 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
17 INT233510 Wnt5a Positive_regulation of Gene_expression of Il12a 1 0.03 0.33 0.1
18 INT211960 Wnt5a Positive_regulation of Car2 1 0.13 0.38 0.08
19 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
20 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08
21 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
22 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
23 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
24 INT343538 TGFB1 Positive_regulation of Gene_expression of GLI2 1 0.08 0.2 0.05
25 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
26 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
27 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
28 INT343545 Binding of GLI2 and ROCK1 1 0.07 0.65 0.03
29 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
30 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
31 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
32 INT343544 Negative_regulation of GLI2 Negative_regulation of Gene_expression of PTHLH 1 0.24 0.53 0.03
33 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
34 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
35 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
36 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
37 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
38 INT335884 Akt1 Regulation of Positive_regulation of Wnt5a 1 0.03 0.15 0
39 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
40 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
41 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
42 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
43 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
44 INT207374 Gene_expression of GLI2 Negative_regulation of Gene_expression of Chol1 1 0.04 0 0
45 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
46 INT343548 GLI2 Positive_regulation of Gene_expression of PTHLH 1 0.28 0.94 0
47 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0
48 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
49 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
50 INT343549 GLI2 Positive_regulation of GYPA 1 0.05 0.95 0
51 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
52 INT207336 Gene_expression of GLI2 Negative_regulation of Gene_expression of CYP27A1 1 0.00 0 0
53 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
54 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
55 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
56 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
57 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
58 INT343539 GLI2 Regulation of PTHLH 1 0.15 0.25 0
59 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
60 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for hindgut morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in hindgut morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
2 INT64170 Gene_expression of GLI2 31 0.46 14.96 3.99
3 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
4 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
5 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
6 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
7 INT90926 Positive_regulation of GLI2 12 0.45 4.99 1.74
8 INT140245 Binding of Gli3 3 0.36 2.65 1.46
9 INT104839 Negative_regulation of GLI2 8 0.35 2.7 1.24
10 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
11 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
12 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
13 INT119674 Localization of GLI2 6 0.52 2.84 0.99
14 INT182322 Negative_regulation of Gene_expression of GLI2 6 0.11 2.37 0.98
15 INT64173 Regulation of Gene_expression of GLI2 4 0.37 2.89 0.88
16 INT289474 Regulation of GLI2 2 0.06 1.08 0.87
17 INT104840 Binding of GLI2 6 0.08 1.89 0.72
18 INT68560 Regulation of Gli3 3 0.18 1.51 0.68
19 INT150075 Positive_regulation of Gene_expression of WNT5A 2 0.67 2.53 0.59
20 INT135062 Transcription of Gli3 1 0.05 0 0.52
21 INT206484 Localization of Shh 2 0.75 1.14 0.46
22 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
23 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
24 INT119675 Positive_regulation of Localization of GLI2 1 0.32 0.43 0.3
25 INT234407 Positive_regulation of Binding of GLI2 2 0.05 1.33 0.28
26 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
27 INT135061 Protein_catabolism of Gli3 1 0.04 0 0.25
28 INT303943 Protein_catabolism of GLI2 2 0.11 0 0.22
29 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
30 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
31 INT135060 Negative_regulation of Transcription of Gli3 1 0.03 0 0.19
32 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
33 INT182321 Positive_regulation of Gene_expression of GLI2 2 0.28 1.32 0.16
34 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
35 INT253190 Localization of Shh 2 0.77 1.06 0.13
36 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
37 INT270451 Localization of Gli3 1 0.26 0.63 0.11
38 INT162574 Gene_expression of Wnt5a 7 0.47 0.92 0.1
39 INT282594 Localization of WNT5A 2 0.18 0.89 0.1
40 INT233483 Regulation of Gene_expression of Wnt5a 1 0.19 0.33 0.1
41 INT270442 Transcription of Shh 1 0.53 0.25 0.09
42 INT135063 Regulation of Gene_expression of Gli3 1 0.04 0 0.09
43 INT213515 Binding of Shh 8 0.37 1.92 0.08
44 INT162576 Positive_regulation of Wnt5a 3 0.48 0.71 0.08
45 INT270453 Regulation of Shh 1 0.27 0.83 0.08
46 INT126375 Negative_regulation of Gene_expression of Gli3 1 0.58 0.79 0.08
47 INT205973 Binding of SHH 3 0.35 1.03 0.07
48 INT290078 Regulation of WNT5A 1 0.07 2.3 0.07
49 INT256862 Regulation of Shh 1 0.25 0 0.07
50 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
51 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
52 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
53 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
54 INT253181 Transcription of Shh 1 0.68 0.54 0.03
55 INT207371 Positive_regulation of Transcription of GLI2 1 0.03 0.08 0
56 INT335880 Regulation of Wnt5a 1 0.32 0.07 0
57 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
58 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
59 INT307407 Regulation of Localization of GLI2 1 0.01 0.67 0
60 INT207369 Transcription of GLI2 1 0.05 0.08 0
61 INT290929 Binding of Shh 1 0.31 0.1 0
62 INT162572 Positive_regulation of Gene_expression of Wnt5a 1 0.02 0.3 0
63 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
64 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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