GO:0007498

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Name mesoderm development
Categary Process
Go Slim No
Go Link GO:0007498
Unique Molecular Interactions 659
Total Molecular Interactions 1019
Total Single Events 7848
Pain Genes Associated 29

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mesoderm development. They are ordered first by their pain relevance and then by number of times they were reported for mesoderm development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
2 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
3 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
4 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
5 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
6 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
7 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
8 INT298260 Binding of Runx3 and Pou4f1 1 0.52 2.08 1.22
9 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
10 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
11 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
12 INT189844 Churc1 Positive_regulation of Cnr2 1 0.01 0.79 1.02
13 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
14 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
15 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
16 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
17 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
18 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
19 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
20 INT63594 Snai1 Negative_regulation of Binding of Ugt1a2 1 0.05 0.32 0.82
21 INT63596 Snai1 Negative_regulation of ITS 1 0.00 0.31 0.81
22 INT298279 Pou4f1 Positive_regulation of Gene_expression of Runx3 1 0.50 1.31 0.81
23 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
24 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
25 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
26 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
27 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
28 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
29 INT287099 Binding of Bdnf and T 1 0.10 1.1 0.69
30 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
31 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
32 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
33 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
34 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
35 INT298262 Pou4f1 Positive_regulation of Positive_regulation of Ntrk3 1 0.36 0.79 0.63
36 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
37 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
38 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
39 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
40 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
41 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
42 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
43 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
44 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
45 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
46 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
47 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
48 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
49 INT101087 NTF3 Positive_regulation of Gene_expression of IKZF1 1 0.04 0.3 0.55
50 INT223556 Churc1 Regulation of Cnr2 1 0.00 0.8 0.54
51 INT194918 Csf2 Positive_regulation of Gene_expression of VEGFA 1 0.02 0.85 0.52
52 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
53 INT127430 VEGFA Negative_regulation of Gene_expression of TIMP1 1 0.43 0.6 0.5
54 INT108692 NTF3 Regulation of Gene_expression of IKZF1 1 0.69 0.7 0.49
55 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49
56 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49
57 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
58 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
59 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48
60 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48
61 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
62 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47
63 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
64 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
65 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
66 INT224698 Il17a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
67 INT224699 Il18 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
68 INT224451 Il1 Positive_regulation of Gene_expression of VEGFA 1 0.10 1.08 0.45
69 INT224434 TNF Positive_regulation of VEGFA 1 0.10 2.04 0.44
70 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43
71 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43
72 INT298263 Pou4f1 Regulation of Gene_expression of Ntrk1 1 0.34 0.61 0.43
73 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
74 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
75 INT153720 Binding of VEGFA and Pscs 1 0.32 3.12 0.41
76 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41
77 INT189843 Churc1 Regulation of Gene_expression of Ik 1 0.00 0.73 0.41
78 INT189846 Binding of Cd40 and Churc1 1 0.01 0.73 0.41
79 INT298259 Pou4f1 Negative_regulation of Gene_expression of Runx3 1 0.46 0.58 0.4
80 INT313455 Binding of Ppp2ca and Syp 1 0.45 0.68 0.4
81 INT196828 Prkaca Positive_regulation of Ppp2ca 1 0.20 0 0.4
82 INT298261 Pou4f1 Negative_regulation of Gene_expression of Runx1 1 0.45 0.58 0.4
83 INT204793 T Positive_regulation of Mthfd1 1 0.00 1.32 0.39
84 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39
85 INT285205 Binding of VEGFA and SLEB1 1 0.05 5.12 0.38
86 INT303994 Il6 Positive_regulation of JAK2 1 0.03 0.41 0.37
87 INT342623 Binding of VEGFA and Col18a1 1 0.02 1.15 0.37
88 INT342606 Binding of MMP14 and VEGFA 1 0.08 1.16 0.37
89 INT298281 Pou4f1 Regulation of Gene_expression of Runx3 1 0.66 0.61 0.37
90 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
91 INT277355 VEGFA Regulation of Trerf1 1 0.08 1.17 0.37
92 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
93 INT277352 Gene_expression of VEGFA Regulation of Trerf1 1 0.08 1.16 0.37
94 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
95 INT329449 IL17A Regulation of Gene_expression of Vegfa 1 0.28 0.63 0.36
96 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35
97 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
98 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34
99 INT352231 VEGFA Negative_regulation of Cntf 1 0.04 0.22 0.34
100 INT352230 VEGFA Negative_regulation of Gene_expression of Cntf 1 0.04 0.22 0.34
101 INT352232 VEGFA Negative_regulation of Vegfa 1 0.02 0.21 0.34
102 INT110691 Lta Positive_regulation of Gene_expression of VEGFA 1 0.24 0.48 0.33
103 INT295717 VEGFA Regulation of MMP9 1 0.01 0.98 0.33
104 INT298285 Pou4f1 Positive_regulation of Runx3 1 0.50 0.56 0.32
105 INT329448 IL17A Positive_regulation of Gene_expression of Vegfa 1 0.45 0.59 0.32
106 INT298269 Positive_regulation of Pou4f1 Positive_regulation of Runx3 1 0.50 0.56 0.32
107 INT235869 Binding of Slc6a4 and Ppp2ca 1 0.04 0.21 0.31
108 INT156151 POU4F1 Positive_regulation of Gene_expression of NTRK1 1 0.46 0.37 0.31
109 INT156163 POU4F1 Positive_regulation of NTRK1 1 0.46 0.37 0.31
110 INT235872 Phosphorylation of Ppp2ca Positive_regulation of Slc37a4 1 0.00 0.15 0.31
111 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3
112 INT203529 Pou4f1 Regulation of target gene 1 0.01 0.53 0.3
113 INT298264 Binding of Pou4f1 and Hist1h3f 1 0.12 0.49 0.3
114 INT210953 Binding of VEGFA and Csf2 1 0.00 0.47 0.3
115 INT281797 Positive_regulation of Chrna4 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.43 0.3
116 INT235886 Ppp2ca Positive_regulation of Slc37a4 1 0.00 0.15 0.3
117 INT203526 Regulation of Pou4f1 Regulation of target gene 1 0.01 0.54 0.3
118 INT150351 Binding of EXT1 and MMP12 1 0.04 3.68 0.29
119 INT298282 Pou4f1 Regulation of Gene_expression of Runx1 1 0.48 0.36 0.29
120 INT196825 Prkaca Positive_regulation of Phosphorylation of Ppp2ca 1 0.20 0 0.29
121 INT156152 POU4F1 Positive_regulation of Positive_regulation of NTRK1 1 0.31 0.38 0.29
122 INT196831 Positive_regulation of Prkaca Positive_regulation of Ppp2ca 1 0.20 0 0.29
123 INT196814 Negative_regulation of Prkaca Positive_regulation of Ppp2ca 1 0.17 0 0.29
124 INT266800 Dlst Positive_regulation of Localization of VEGFA 1 0.02 0.88 0.29
125 INT156149 Binding of HCFC1 and POU4F1 1 0.27 0.39 0.28
126 INT156154 POU4F1 Positive_regulation of HCFC1 1 0.36 0.38 0.28
127 INT254353 Binding of VEGFA and MMRN1 1 0.00 0.81 0.28
128 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27
129 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27
130 INT103156 Tnf Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.94 0.27
131 INT287699 TNF Regulation of Binding of VEGFA 1 0.02 0.46 0.27
132 INT318551 Binding of VEGFA and Adamts1 1 0.13 1.13 0.27
133 INT285238 EGF Positive_regulation of VEGFA 1 0.01 1.55 0.27
134 INT298277 Pou4f1 Negative_regulation of Gene_expression of Neurod1 1 0.58 0.48 0.27
135 INT298280 Pou4f1 Negative_regulation of Gene_expression of Neurod4 1 0.38 0.48 0.27
136 INT156150 POU4F1 Regulation of Gene_expression of NTRK1 1 0.18 0.39 0.27
137 INT248318 RETN Regulation of VEGFA 1 0.00 0.43 0.26
138 INT313446 Syp Regulation of Ppp2ca 1 0.58 0.62 0.26
139 INT109538 Lox Negative_regulation of Transcription of VEGFA 1 0.30 0.69 0.26
140 INT260423 IFNA1 Positive_regulation of Gene_expression of VEGFA 1 0.01 1.28 0.26
141 INT254359 IL1B Positive_regulation of Localization of VEGFA 1 0.01 0.87 0.26
142 INT103152 TNF Positive_regulation of Positive_regulation of VEGFA 1 0.09 0.93 0.26
143 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26
144 INT126887 Protein_catabolism of SP4 Negative_regulation of Gene_expression of VEGFA 1 0.15 0.49 0.26
145 INT266803 Dlst Positive_regulation of VEGFA 1 0.01 0.96 0.25
146 INT109539 Lox Negative_regulation of VEGFA 1 0.40 0.68 0.25
147 INT145660 Zfp329 Positive_regulation of Gene_expression of VEGFA 1 0.00 0.51 0.25
148 INT241401 VEGFA Positive_regulation of Gene_expression of Gopc 1 0.11 0.85 0.25
149 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
150 INT98631 Negative_regulation of VEGFA Positive_regulation of EGR1 1 0.44 0.18 0.24
151 INT298297 Pou4f1 Positive_regulation of Gene_expression of Ntrk2 1 0.50 0.36 0.24
152 INT98630 VEGFA Positive_regulation of EGR1 1 0.52 0.18 0.24
153 INT298290 Pou4f1 Regulation of Gene_expression of Ntrk2 1 0.29 0.48 0.23
154 INT287098 Binding of FL and T 1 0.10 0.66 0.23
155 INT304323 VEGFA Positive_regulation of Gene_expression of Ptger2 1 0.27 0.16 0.23
156 INT118840 VEGFA Regulation of Positive_regulation of Mb 1 0.05 0.36 0.23
157 INT163403 VEGFA Positive_regulation of MMP2 1 0.52 0.13 0.23
158 INT323436 VEGFA Regulation of Kdr 1 0.03 0.77 0.23
159 INT304321 Ptger4 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.59 0.23
160 INT304324 VEGFA Positive_regulation of Gene_expression of Ptger4 1 0.27 0.16 0.23
161 INT245866 Binding of VEGFA and Fgf1 1 0.07 0.52 0.22
162 INT90280 Binding of Ppp1cc and Ppp2ca 1 0.34 0.22 0.22
163 INT118838 Gene_expression of Vegfa Positive_regulation of Gene_expression of Mb 1 0.44 0.4 0.22
164 INT318189 MUC5AC Regulation of Gene_expression of VEGFA 1 0.21 1.17 0.22
165 INT137611 Crh Positive_regulation of Vegfa 1 0.43 0.49 0.21
166 INT116467 Vegfa Positive_regulation of Akt1 1 0.33 1.41 0.21
167 INT137612 Crh Positive_regulation of Positive_regulation of Vegfa 1 0.43 0.43 0.21
168 INT114837 Il1b Negative_regulation of Vegfa 1 0.26 3.04 0.21
169 INT163096 Tlr2 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.16 0.21
170 INT116469 VEGFA Positive_regulation of Amfr 1 0.01 1.39 0.21
171 INT116468 VEGFA Positive_regulation of Akt1 1 0.04 1.39 0.21
172 INT116466 Vegfa Positive_regulation of Amfr 1 0.07 1.41 0.21
173 INT137610 Crh Positive_regulation of Localization of Vegfa 1 0.43 0.49 0.21
174 INT345196 Lpar2 Positive_regulation of Gene_expression of VEGFA 1 0.08 2.14 0.2
175 INT203527 Pou4f1 Negative_regulation of Neurod1 1 0.32 0.54 0.2
176 INT174861 Binding of FGF2 and VEGFA 1 0.34 0.59 0.2
177 INT236405 Mthfs Regulation of Gene_expression of VEGFA 1 0.00 0.25 0.2
178 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
179 INT189553 DCN Negative_regulation of Transcription of VEGFA 1 0.06 0.78 0.2
180 INT203531 Pou4f1 Negative_regulation of Neurod4 1 0.46 0.54 0.2
181 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19
182 INT175727 IL1B Regulation of VEGFA 2 0.04 0.7 0.19
183 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19
184 INT203532 Negative_regulation of Pou4f1 Negative_regulation of Gene_expression of Pou4f2 1 0.34 0.44 0.19
185 INT282866 Bpifa2 Negative_regulation of Gene_expression of VEGFA 1 0.11 1.14 0.19
186 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
187 INT287097 T Positive_regulation of Ntrk2 1 0.21 0.6 0.19
188 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
189 INT110692 Lta Regulation of Gene_expression of VEGFA 1 0.14 0.28 0.19
190 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19
191 INT304325 Positive_regulation of Ptger2 Positive_regulation of Gene_expression of VEGFA 1 0.25 0.23 0.19
192 INT337697 FGF2 Regulation of VEGFA 1 0.03 0.51 0.18
193 INT113809 Negative_regulation of Cpox Negative_regulation of Gene_expression of VEGFA 1 0.02 0.97 0.18
194 INT298273 Binding of Pou4f1 and target gene site 1 0.01 0.53 0.18
195 INT337698 VEGFA Regulation of FGFR1 1 0.09 0.51 0.18
196 INT203528 Binding of Pou4f1 and H3 1 0.17 0.42 0.18
197 INT330514 Vegfa Positive_regulation of VEGFA 1 0.18 0.5 0.18
198 INT306425 Positive_regulation of Binding of TBX1 and VCF 1 0.02 1.15 0.18
199 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
200 INT306426 Binding of TBX1 and VCF 1 0.01 1.09 0.17

Single Events

The table below shows the top 100 pain related interactions that have been reported for mesoderm development. They are ordered first by their pain relevance and then by number of times they were reported in mesoderm development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
3 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
4 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
5 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
6 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
7 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
8 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
9 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
10 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
11 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
12 INT203473 Gene_expression of Pou4f1 69 0.76 25.94 11.36
13 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
14 INT1223 Negative_regulation of Snai1 15 0.38 2.05 8.46
15 INT20914 Positive_regulation of Snai1 13 0.41 3.41 7.69
16 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
17 INT105215 Negative_regulation of Pou4f1 16 0.53 9.42 5.97
18 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
19 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
20 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
21 INT203506 Positive_regulation of Pou4f1 3 0.49 6.17 4.85
22 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
23 INT204449 Gene_expression of T 17 0.32 9.77 4.77
24 INT196782 Positive_regulation of Ppp2ca 32 0.61 1.89 4.33
25 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
26 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
27 INT90277 Negative_regulation of Ppp2ca 15 0.41 4.04 4.02
28 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
29 INT105217 Regulation of Pou4f1 8 0.60 6.15 3.88
30 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
31 INT196779 Phosphorylation of Ppp2ca 28 0.72 1.86 3.25
32 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
33 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
34 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
35 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
36 INT132773 Negative_regulation of Acvr2b 3 0.41 1.55 2.87
37 INT1225 Regulation of Snai1 10 0.30 1.05 2.72
38 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
39 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43
40 INT113339 Binding of JAK2 6 0.40 5.31 2.4
41 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
42 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
43 INT269217 Gene_expression of SNAI1 81 0.76 80.49 2.26
44 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16
45 INT17688 Positive_regulation of IKZF1 5 0.50 0.48 2.11
46 INT53434 Positive_regulation of T 7 0.07 3.67 2.09
47 INT90272 Gene_expression of Ppp2ca 18 0.68 4.69 2.08
48 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
49 INT136818 Positive_regulation of Phosphorylation of VEGFA 4 0.46 0.81 2.02
50 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92
51 INT107178 Gene_expression of Smad4 12 0.65 9.85 1.92
52 INT104912 Gene_expression of Acvr2a 8 0.63 4.48 1.81
53 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
54 INT32024 Positive_regulation of Positive_regulation of Snai1 2 0.25 0.32 1.7
55 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
56 INT55302 Binding of Snai1 2 0.31 1.94 1.63
57 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
58 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6
59 INT101090 Gene_expression of IKZF1 6 0.77 2.98 1.58
60 INT89116 Regulation of Positive_regulation of VEGFA 8 0.43 6.62 1.5
61 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
62 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
63 INT144805 Regulation of Negative_regulation of Ppp2ca 1 0.28 0.24 1.38
64 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
65 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
66 INT226407 Negative_regulation of T 2 0.21 1.81 1.18
67 INT196785 Regulation of Ppp2ca 5 0.54 2.1 1.17
68 INT203436 Negative_regulation of Gene_expression of Pou4f1 4 0.57 2.88 1.14
69 INT298235 Binding of Pou4f1 1 0.47 2.95 1.11
70 INT208427 Regulation of T 3 0.25 3.28 1.08
71 INT203498 Localization of Pou4f1 5 0.73 3.29 1.07
72 INT97032 Gene_expression of Snai1 3 0.52 0.58 1.04
73 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99
74 INT198049 Positive_regulation of JAK2 16 0.58 5.35 0.96
75 INT24266 Negative_regulation of IKZF1 6 0.37 1.55 0.96
76 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
77 INT90278 Localization of Ppp2ca 4 0.66 1.12 0.94
78 INT243240 Transcription of Pou4f1 2 0.68 1.91 0.94
79 INT196754 Binding of Ppp2ca 5 0.37 0.42 0.89
80 INT287093 Positive_regulation of Gene_expression of T 1 0.28 1.47 0.86
81 INT287090 Regulation of Gene_expression of T 1 0.18 2.77 0.86
82 INT203489 Positive_regulation of Gene_expression of Pou4f1 3 0.49 2.33 0.84
83 INT211488 Regulation of Binding of VEGFA 5 0.43 3.72 0.83
84 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82
85 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81
86 INT176488 Gene_expression of TIE1 2 0.49 3.7 0.81
87 INT287094 Transcription of T 1 0.29 1.41 0.8
88 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79
89 INT101091 Regulation of IKZF1 3 0.09 0.3 0.79
90 INT114604 Positive_regulation of Acvr2a 2 0.41 0 0.73
91 INT143445 Protein_catabolism of VEGFA 12 0.85 4.14 0.72
92 INT113342 Positive_regulation of Phosphorylation of JAK2 2 0.66 2.58 0.72
93 INT12443 Regulation of Localization of Vegfa 2 0.20 0 0.72
94 INT172960 Negative_regulation of Gene_expression of Smad4 7 0.39 5.88 0.71
95 INT196753 Negative_regulation of Phosphorylation of Ppp2ca 3 0.37 0.52 0.7
96 INT196742 Positive_regulation of Positive_regulation of Ppp2ca 4 0.44 0.05 0.68
97 INT226411 Binding of T 2 0.15 1.56 0.68
98 INT340625 Protein_catabolism of Vegfa 1 0.05 1.61 0.64
99 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
100 INT174868 Regulation of Negative_regulation of VEGFA 4 0.43 4.51 0.63
101 INT296253 Negative_regulation of Gene_expression of Ppp2ca 3 0.41 1.71 0.62
102 INT196765 Positive_regulation of Gene_expression of Ppp2ca 4 0.44 1.05 0.6
103 INT54000 Positive_regulation of SNAI1 7 0.49 5.37 0.58
104 INT174873 Regulation of Transcription of VEGFA 8 0.43 3.71 0.55
105 INT103781 Negative_regulation of Smad4 9 0.42 4.42 0.54
106 INT172964 Binding of Vegfa 14 0.47 10.62 0.53
107 INT105677 Binding of Vegfa 7 0.37 5.22 0.51
108 INT125207 Positive_regulation of Negative_regulation of Pou4f1 1 0.21 0.69 0.5
109 INT340598 Binding of Wnt3a 1 0.33 0.15 0.46
110 INT218293 Gene_expression of Acvr2b 14 0.76 4.22 0.44
111 INT71019 Negative_regulation of SMAD4 12 0.42 6.88 0.43
112 INT247568 Negative_regulation of Negative_regulation of VEGFA 5 0.41 5.35 0.43
113 INT159221 Negative_regulation of TBX1 4 0.41 4.22 0.43
114 INT268877 Regulation of Gene_expression of Vegfa 2 0.58 4.73 0.42
115 INT203518 Regulation of Localization of Pou4f1 1 0.44 1.15 0.42
116 INT152023 Regulation of Vegfa 4 0.52 3.99 0.41
117 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
118 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
119 INT65606 Binding of TBX1 2 0.30 3.13 0.41
120 INT43720 Regulation of Positive_regulation of Vegfa 1 0.03 0.41 0.41
121 INT287095 Negative_regulation of Gene_expression of T 1 0.24 0.47 0.41
122 INT43722 Positive_regulation of Regulation of Vegfa 1 0.06 0.41 0.41
123 INT176493 Positive_regulation of TIE1 1 0.13 0.64 0.4
124 INT340606 Positive_regulation of Wnt3a 1 0.61 0.49 0.4
125 INT129849 Positive_regulation of Localization of Vegfa 1 0.46 0.35 0.39
126 INT117564 Gene_expression of SMAD4 12 0.71 8.7 0.37
127 INT123578 Negative_regulation of Gene_expression of Snai1 1 0.33 0.5 0.36
128 INT123579 Negative_regulation of Positive_regulation of Snai1 1 0.33 0.51 0.36
129 INT131415 Gene_expression of POU4F1 1 0.60 1.87 0.36
130 INT135495 Regulation of Positive_regulation of Snai1 1 0.23 0 0.33
131 INT92100 Binding of Smad4 5 0.31 2.23 0.3
132 INT269225 Negative_regulation of Gene_expression of SNAI1 4 0.58 9.11 0.28
133 INT51514 Positive_regulation of Wnt3a 3 0.04 3.32 0.28
134 INT269082 Gene_expression of TBX1 1 0.14 0.36 0.28
135 INT224619 Regulation of Positive_regulation of Vegfa 1 0.05 0.57 0.27
136 INT224638 Positive_regulation of Positive_regulation of Vegfa 1 0.06 0.57 0.27
137 INT148796 Regulation of Phosphorylation of VEGFA 3 0.35 1.66 0.26
138 INT109537 Transcription of Vegfa 2 0.44 1.32 0.26
139 INT303972 Positive_regulation of Gene_expression of JAK2 2 0.63 1.3 0.24
140 INT137608 Regulation of Localization of Vegfa 1 0.25 0.56 0.24
141 INT306427 Localization of TBX1 1 0.20 1.08 0.23
142 INT118478 Transcription of IKZF1 1 0.48 0.52 0.23
143 INT306428 Positive_regulation of Localization of TBX1 1 0.14 1.08 0.23
144 INT140639 Gene_expression of FOXF1 3 0.52 0.89 0.22
145 INT189837 Gene_expression of Churc1 2 0.01 0.43 0.22
146 INT196761 Regulation of Positive_regulation of Ppp2ca 2 0.40 0.05 0.22
147 INT291969 Negative_regulation of Gene_expression of IKZF1 1 0.13 1.15 0.22
148 INT196763 Positive_regulation of Regulation of Ppp2ca 1 0.30 0 0.21
149 INT58734 Regulation of SNAI1 3 0.60 1.26 0.2
150 INT206159 Negative_regulation of Regulation of VEGFA 3 0.24 2.38 0.2
151 INT196759 Negative_regulation of Negative_regulation of Ppp2ca 2 0.30 0.17 0.2
152 INT181794 Positive_regulation of Gene_expression of TIE1 1 0.31 1.26 0.2
153 INT162483 Localization of Snai1 1 0.43 0 0.19
154 INT162484 Regulation of Localization of Snai1 1 0.33 0 0.19
155 INT269228 Binding of SNAI1 1 0.47 2.28 0.18
156 INT277935 Binding of SMAD4 4 0.28 1.12 0.17
157 INT181783 Transcription of SNAI1 3 0.71 2.44 0.17
158 INT58735 Negative_regulation of Regulation of SNAI1 1 0.33 0.24 0.17
159 INT196770 Negative_regulation of Positive_regulation of Ppp2ca 1 0.27 0 0.16
160 INT139977 Regulation of Smad4 1 0.16 1.41 0.15
161 INT203450 Negative_regulation of Localization of Pou4f1 1 0.42 0.4 0.14
162 INT200943 Negative_regulation of PPP2CA 1 0.10 0.13 0.14
163 INT249096 Regulation of FOXF1 1 0.19 0.28 0.14
164 INT291973 Binding of IKZF1 1 0.13 0.52 0.14
165 INT131412 Regulation of POU4F1 1 0.21 0.69 0.14
166 INT307932 Localization of Snai1 3 0.78 2.28 0.13
167 INT131409 Positive_regulation of Gene_expression of POU4F1 1 0.54 0.63 0.13
168 INT316436 Positive_regulation of Snai1 1 0.22 0.35 0.13
169 INT51512 Negative_regulation of Positive_regulation of Wnt3a 1 0.04 1.3 0.13
170 INT51513 Positive_regulation of Positive_regulation of Wnt3a 1 0.04 1.31 0.13
171 INT222585 Transcription of Acvr2a 1 0.16 0 0.13
172 INT302444 Negative_regulation of Binding of Vegfa 2 0.57 4.08 0.12
173 INT246872 Negative_regulation of Localization of Vegfa 2 0.41 2.16 0.12
174 INT260740 Negative_regulation of Localization of Vegfa 1 0.10 0.19 0.12
175 INT162568 Regulation of TBX1 3 0.35 1.54 0.11
176 INT258933 Protein_catabolism of TBX1 1 0.43 0.75 0.11
177 INT313409 Positive_regulation of Phosphorylation of Ppp2ca 1 0.39 0.16 0.11
178 INT203492 Negative_regulation of Positive_regulation of Pou4f1 1 0.36 0.68 0.11
179 INT313423 Positive_regulation of Localization of Ppp2ca 1 0.44 0.12 0.1
180 INT213448 Localization of FOXF1 1 0.58 0.15 0.1
181 INT312354 Regulation of Gene_expression of JAK2 1 0.25 1.17 0.1
182 INT184511 Positive_regulation of Negative_regulation of VEGFA 5 0.46 2.86 0.09
183 INT196033 Negative_regulation of Gene_expression of Bmp4 3 0.21 0.45 0.09
184 INT325510 Transcription of Smad4 1 0.67 0.16 0.09
185 INT214463 Binding of Wnt3a 2 0.26 0.23 0.08
186 INT213440 Negative_regulation of FOXF1 1 0.33 0.14 0.08
187 INT247569 Positive_regulation of Regulation of VEGFA 6 0.48 4.15 0.07
188 INT269218 Localization of SNAI1 4 0.79 3.1 0.07
189 INT254790 Localization of Smad4 2 0.37 0.54 0.06
190 INT289490 Negative_regulation of Negative_regulation of Pou4f1 1 0.32 0.09 0.06
191 INT310747 Regulation of JAK2 2 0.33 1.58 0.05
192 INT238202 Negative_regulation of Localization of JAK2 1 0.09 0 0.05
193 INT238200 Localization of JAK2 1 0.16 0 0.05
194 INT355863 Binding of EXT1 1 0.20 6.43 0.05
195 INT196030 Positive_regulation of Bmp4 6 0.62 2.55 0.04
196 INT298445 Positive_regulation of Gene_expression of SNAI1 4 0.59 5.07 0.04
197 INT294427 Regulation of Gene_expression of Vegfa 2 0.44 2.4 0.04
198 INT269219 Phosphorylation of SNAI1 1 0.62 0.38 0.04
199 INT253182 Positive_regulation of Positive_regulation of Bmp4 1 0.45 0.58 0.04
200 INT313406 Positive_regulation of Binding of Ppp2ca 1 0.44 0 0.04
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