GO:0007507

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Name heart development
Categary Process
Go Slim No
Go Link GO:0007507
Unique Molecular Interactions 3017
Total Molecular Interactions 4276
Total Single Events 38556
Pain Genes Associated 245

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for heart development. They are ordered first by their pain relevance and then by number of times they were reported for heart development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
2 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
3 INT11613 Cck Positive_regulation of Localization of Oxt 3 0.53 0 4.17
4 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
5 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
6 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
7 INT130085 Crp Positive_regulation of Gene_expression of Vcam1 1 0.23 4.34 2.84
8 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
9 INT107812 Nppa Positive_regulation of Localization of Sst 1 0.48 0.54 2.51
10 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
11 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
12 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
13 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
14 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
15 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
16 INT66803 Oxt Regulation of Avp 7 0.16 0.19 2.15
17 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
18 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12
19 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
20 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
21 INT334532 Sema3a Negative_regulation of Gene_expression of Nrp1 1 0.19 7.58 2
22 INT213973 Binding of Pax3 and Mthfd1 1 0.00 0.16 1.99
23 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
24 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
25 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
26 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
27 INT40238 Penk Regulation of Oxt 1 0.04 0 1.83
28 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
29 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
30 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
31 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
32 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69
33 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
34 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
35 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
36 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
37 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
38 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
39 INT63939 Vta1 Positive_regulation of Th 1 0.14 0 1.61
40 INT48790 Negative_regulation of Rtcd1 Negative_regulation of Pax3 1 0.02 0 1.59
41 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
42 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
43 INT107815 Gene_expression of Sst Positive_regulation of Localization of Nppa 1 0.52 0.27 1.57
44 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
45 INT40887 Penk Regulation of Th 1 0.04 0 1.53
46 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
47 INT64628 Binding of Oxt and Gal 2 0.29 0.29 1.49
48 INT276687 Pax3 Positive_regulation of Nkx1-1 1 0.00 0.59 1.47
49 INT107813 Sst Negative_regulation of Localization of Nppa 1 0.44 0.2 1.46
50 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
51 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
52 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
53 INT298458 Binding of Calcrl and Adarb1 1 0.00 0.23 1.41
54 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
55 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4
56 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
57 INT26812 SST Regulation of Localization of OXT 1 0.40 0.57 1.37
58 INT30089 Cck Regulation of Localization of Oxt 2 0.45 0.19 1.36
59 INT106070 Positive_regulation of Oprl1 Positive_regulation of TH 1 0.13 0.15 1.36
60 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
61 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
62 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
63 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
64 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
65 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
66 INT31771 Penk Positive_regulation of Nppa 1 0.22 0.13 1.28
67 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
68 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
69 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
70 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
71 INT136644 T(1;9)27H Negative_regulation of Gene_expression of Hand1 1 0.15 1.14 1.27
72 INT31773 Pdyn Positive_regulation of Nppa 1 0.12 0.13 1.27
73 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
74 INT118784 Thop1 Positive_regulation of Protein_catabolism of Pax3 1 0.07 0.07 1.25
75 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
76 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
77 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
78 INT7887 Oprl1 Regulation of Localization of Oxt 2 0.16 0 1.23
79 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
80 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
81 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
82 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
83 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
84 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
85 INT90644 Slc6a3 Positive_regulation of Th 1 0.51 0 1.2
86 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
87 INT172500 Ednra Positive_regulation of Coc 1 0.01 1 1.2
88 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
89 INT351715 Pax3 Negative_regulation of Adarb1 1 0.00 0 1.19
90 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
91 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
92 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
93 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
94 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
95 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
96 INT189017 Binding of Pax3 and Lmna 1 0.14 0.42 1.16
97 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
98 INT48809 Pax3 Negative_regulation of Binding of Tac1 1 0.22 0 1.16
99 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
100 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
101 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
102 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14
103 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
104 INT106069 TH Positive_regulation of Th 1 0.07 0.16 1.14
105 INT30359 Pomc Regulation of Localization of Oxt 1 0.03 0 1.13
106 INT222516 Binding of Calcrl and Ramp1 5 0.17 0.11 1.12
107 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
108 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12
109 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
110 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
111 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
112 INT88446 Uncx Positive_regulation of Th 1 0.13 0 1.1
113 INT29874 OXTR Negative_regulation of POMC 1 0.22 0 1.1
114 INT44838 Pitpnm1 Negative_regulation of Th 1 0.02 0 1.09
115 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
116 INT31547 Binding of Th and Vip 1 0.31 0 1.08
117 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08
118 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 1 0.32 0.42 1.07
119 INT107938 POMC Positive_regulation of Gene_expression of TGFBR2 1 0.42 1.09 1.07
120 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07
121 INT87222 Nrg1 Regulation of Oprd1 1 0.00 0 1.07
122 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
123 INT150787 ZNF398 Positive_regulation of Gene_expression of SPARC 1 0.13 1.02 1.05
124 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
125 INT221 Chd7 Negative_regulation of Th 1 0.02 0 1.04
126 INT41175 Adra2a Regulation of Th 1 0.59 0 1.04
127 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
128 INT117908 Em Regulation of Localization of Pax3 1 0.00 0.07 1.03
129 INT134213 CRH Positive_regulation of Gene_expression of ENG 1 0.13 0.61 1.03
130 INT98555 Oprm1 Positive_regulation of Casp8 1 0.51 0.36 1.02
131 INT63103 AVP Regulation of OXT 1 0.28 0.68 1.02
132 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02
133 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
134 INT49164 Binding of Pax3 and Nka1 1 0.01 0.37 1.01
135 INT148327 Binding of Pkd1 and Trpv1 1 0.52 2.23 1.01
136 INT49162 Nka1 Negative_regulation of Binding of Pax3 1 0.02 0.37 1.01
137 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
138 INT170449 Pax3 Positive_regulation of Spr 1 0.01 0.26 0.99
139 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99
140 INT209151 OXT Positive_regulation of PNLIP 1 0.08 0.73 0.99
141 INT228496 Il4 Negative_regulation of Hand1 1 0.02 1.4 0.99
142 INT209923 IL17A Negative_regulation of PPARA 1 0.14 2.46 0.99
143 INT31548 Binding of Th and Dbh 1 0.35 0 0.98
144 INT228495 Il13 Negative_regulation of Hand1 1 0.01 1.4 0.98
145 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
146 INT4916 Binding of Pax3 and Wdyhv1 1 0.00 0 0.98
147 INT239539 Binding of CXCR2 and CALCRL 1 0.00 0.38 0.98
148 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97
149 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
150 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
151 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95
152 INT107951 Pax3 Positive_regulation of Tac1 1 0.11 1.21 0.95
153 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
154 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
155 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
156 INT51543 Positive_regulation of Binding of Oxt and Penk 1 0.56 0.05 0.94
157 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
158 INT51544 Binding of Oxt and Penk 1 0.54 0.05 0.94
159 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
160 INT123023 Ednra Regulation of Adarb1 1 0.00 0 0.93
161 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
162 INT72386 Egf Positive_regulation of Phosphorylation of Shc1 1 0.09 0.18 0.93
163 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
164 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
165 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
166 INT123024 Csf2 Regulation of Ednra 1 0.06 0 0.92
167 INT196591 Binding of Lpar1 and Pax3 1 0.05 1.1 0.92
168 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
169 INT32187 Binding of ENG and Negative_regulation of Localization of LH 1 0.01 0 0.91
170 INT334529 Pax3 Positive_regulation of Gene_expression of Ngf 1 0.03 0.31 0.91
171 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91
172 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
173 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
174 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
175 INT28194 Nppb Positive_regulation of CYP2B6 1 0.50 0.05 0.88
176 INT28193 Nppb Positive_regulation of Positive_regulation of RYBP 1 0.29 0.05 0.88
177 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
178 INT14626 Binding of Dpep1 and Pax3 1 0.01 0 0.87
179 INT184916 Binding of da and Th 1 0.09 1.22 0.87
180 INT185329 Pax3 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.00 0.22 0.87
181 INT213977 Pax3 Negative_regulation of Gene_expression of Il2 1 0.00 0.25 0.86
182 INT59396 Tead1 Negative_regulation of Negative_regulation of Man2a2 1 0.00 0 0.86
183 INT59395 Tead1 Negative_regulation of Man2a2 1 0.00 0 0.86
184 INT308495 Pcsk5 Regulation of CFI 1 0.01 0.22 0.85
185 INT114324 RAF1 Positive_regulation of Phosphorylation of ADCY6 1 0.02 0.05 0.85
186 INT146495 Snta1 Positive_regulation of Adrbk1 1 0.14 0.68 0.85
187 INT307045 Tmie Negative_regulation of Positive_regulation of Casp3 1 0.01 0.29 0.85
188 INT114323 Binding of ADCY6 and RAF1 1 0.02 0.05 0.85
189 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
190 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85
191 INT26528 Prl Regulation of Oxt 1 0.26 0.26 0.85
192 INT128701 Ednra Regulation of EDNRB 1 0.17 0.58 0.84
193 INT128702 Ednra Regulation of EDNRA 1 0.00 0.58 0.84
194 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
195 INT122687 Binding of Galr2 and Th 1 0.13 0.07 0.83
196 INT64627 Binding of Oxt and Crh 1 0.07 0.1 0.83
197 INT122688 Binding of Galr1 and Th 1 0.14 0.07 0.83
198 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
199 INT122686 Binding of Galr3 and Th 1 0.14 0.07 0.83
200 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82

Single Events

The table below shows the top 100 pain related interactions that have been reported for heart development. They are ordered first by their pain relevance and then by number of times they were reported in heart development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3579 Localization of Oxt 555 0.81 43.35 292.44
2 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
3 INT4740 Gene_expression of Th 298 0.78 61.27 154.03
4 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
5 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
6 INT218 Positive_regulation of Th 245 0.70 40.5 120.1
7 INT7327 Regulation of Th 164 0.62 29.67 110.14
8 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
9 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7
10 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43
11 INT5617 Localization of Nppa 266 0.81 83.51 83.89
12 INT8534 Localization of Pax3 85 0.59 28.71 82.82
13 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47
14 INT451 Regulation of Oxt 142 0.62 22.07 69.42
15 INT7468 Negative_regulation of Localization of Oxt 109 0.59 9.46 66.79
16 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47
17 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
18 INT217 Negative_regulation of Th 134 0.59 26.83 62.63
19 INT7884 Regulation of Localization of Oxt 102 0.62 7.95 61.71
20 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
21 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57
22 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53
23 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33
24 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
25 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
26 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
27 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
28 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
29 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01
30 INT4913 Binding of Pax3 52 0.28 9.57 42.67
31 INT350 Localization of Th 79 0.80 10.26 41.17
32 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38
33 INT30817 Gene_expression of Th 142 0.76 33.56 38.12
34 INT5620 Positive_regulation of Localization of Nppa 105 0.70 30.23 36.45
35 INT7326 Transcription of Th 83 0.72 13.5 35.33
36 INT103094 Binding of PPARA 308 0.47 177.26 34.75
37 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6
38 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
39 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
40 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69
41 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4
42 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89
43 INT6196 Regulation of Nppa 83 0.62 30.31 30.18
44 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
45 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31
46 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
47 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
48 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97
49 INT10799 Localization of ENG 63 0.78 18.67 27.28
50 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79
51 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
52 INT8205 Negative_regulation of Nppa 77 0.59 26.43 25.72
53 INT28336 Positive_regulation of Pax3 37 0.33 20.94 25.66
54 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31
55 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96
56 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
57 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
58 INT4781 Gene_expression of TH 68 0.73 26.92 24.01
59 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
60 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
61 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
62 INT26719 Negative_regulation of Gene_expression of Th 38 0.58 11.87 22.78
63 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
64 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6
65 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
66 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41
67 INT13643 Phosphorylation of Th 20 0.82 1.9 20.97
68 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
69 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
70 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
71 INT24240 Positive_regulation of Th 60 0.70 9.92 20.18
72 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85
73 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
74 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
75 INT5048 Binding of Edn1 55 0.47 18.86 19.16
76 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15
77 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42
78 INT5533 Binding of Oxt 43 0.48 8.69 18.35
79 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
80 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9
81 INT5618 Regulation of Localization of Nppa 36 0.62 13.42 17.46
82 INT6728 Gene_expression of Ednra 43 0.65 13.41 17.38
83 INT22068 Binding of CALCRL 53 0.41 6.14 17.32
84 INT70557 Negative_regulation of Localization of Pax3 1 0.36 1.15 17.32
85 INT219 Negative_regulation of Th 55 0.59 20.88 17.09
86 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96
87 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
88 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
89 INT104045 Regulation of Hand1 65 0.35 51.32 16.26
90 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2
91 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16
92 INT24241 Phosphorylation of Th 35 0.81 8.69 16.06
93 INT13716 Positive_regulation of TH 33 0.68 19.11 16
94 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98
95 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
96 INT42810 Gene_expression of CALCRL 53 0.77 10.87 15.42
97 INT129 Localization of OXTR 51 0.80 11.08 15.36
98 INT9191 Localization of EDN1 94 0.81 57.01 14.78
99 INT103096 Regulation of PPARA 113 0.60 62.47 14.57
100 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53
101 INT7674 Regulation of ENG 42 0.30 11.41 14.44
102 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
103 INT7469 Positive_regulation of Gene_expression of Oxt 18 0.59 4.7 14.36
104 INT109264 Positive_regulation of Transcription of Th 17 0.50 4.73 14.33
105 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
106 INT6365 Localization of Edn1 56 0.81 18.84 13.83
107 INT79703 Gene_expression of Agtr1a 46 0.76 14.18 13.77
108 INT173505 Localization of Hand2 63 0.57 45.32 13.66
109 INT20378 Localization of Hand1 53 0.71 41.96 13.31
110 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
111 INT14764 Negative_regulation of Localization of Nppa 28 0.59 11.29 12.82
112 INT31368 Positive_regulation of Positive_regulation of Th 19 0.51 2.2 12.68
113 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
114 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5
115 INT63104 Negative_regulation of CALCRL 29 0.37 13.62 12.42
116 INT94464 Negative_regulation of Hand1 44 0.41 31.5 12.39
117 INT9083 Gene_expression of Nppb 74 0.78 70.96 12.19
118 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18
119 INT70556 Positive_regulation of Localization of Pax3 9 0.34 3.13 12.11
120 INT121223 Positive_regulation of Gene_expression of Pax3 17 0.16 4.52 12.06
121 INT70555 Regulation of Pax3 13 0.35 3.62 12.05
122 INT73829 Positive_regulation of Gene_expression of VCAM1 41 0.61 35.96 11.92
123 INT9084 Positive_regulation of Nppb 74 0.70 69.77 11.85
124 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79
125 INT53038 Positive_regulation of Agtr1a 35 0.67 23.76 11.68
126 INT143098 Negative_regulation of Gene_expression of Adrbk1 9 0.58 8.51 11.37
127 INT5464 Regulation of CALCRL 24 0.16 4.2 11.19
128 INT141 Binding of Th 21 0.48 3.53 11.04
129 INT94465 Positive_regulation of Gene_expression of Hand1 43 0.38 29.76 10.88
130 INT78567 Positive_regulation of Gene_expression of Th 25 0.68 5.32 10.75
131 INT2791 Regulation of Mb 53 0.61 23.03 10.73
132 INT1708 Gene_expression of OXTR 56 0.78 6.92 10.69
133 INT54706 Regulation of Adrbk1 11 0.62 0.89 10.69
134 INT9550 Gene_expression of TNNI3 113 0.78 86.79 10.56
135 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
136 INT78695 Regulation of Casp3 24 0.44 9.43 10.48
137 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
138 INT10982 Negative_regulation of Agtr1a 42 0.58 22.42 10.29
139 INT173159 Localization of PPARA 96 0.74 64.55 10.26
140 INT2792 Gene_expression of Mb 91 0.76 41.56 10.25
141 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
142 INT67048 Gene_expression of ITGA4 58 0.75 28.93 10.16
143 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08
144 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
145 INT48496 Regulation of Transcription of Th 16 0.54 2.29 10.02
146 INT76573 Negative_regulation of Vcam1 26 0.58 24.36 9.84
147 INT5465 Positive_regulation of CALCRL 25 0.49 7.24 9.8
148 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76
149 INT6361 Localization of Edn1 30 0.81 19.09 9.7
150 INT54707 Positive_regulation of Adrbk1 14 0.67 0.51 9.51
151 INT78038 Gene_expression of Oxtr 43 0.78 18.72 9.38
152 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28
153 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24
154 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22
155 INT62829 Positive_regulation of VCAM1 39 0.70 38.42 9.15
156 INT5939 Regulation of Gene_expression of Oxt 27 0.51 2.84 9.1
157 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
158 INT67612 Binding of PPARG 38 0.48 22.67 8.94
159 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86
160 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81
161 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79
162 INT6727 Positive_regulation of Ednra 27 0.64 18.75 8.71
163 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66
164 INT7673 Negative_regulation of ENG 31 0.42 7.9 8.61
165 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58
166 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
167 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
168 INT10237 Binding of EDN1 40 0.48 16 8.48
169 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
170 INT26815 Regulation of OXT 15 0.46 5.38 8.31
171 INT109265 Transcription of Th 18 0.68 4.5 8.21
172 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2
173 INT30382 Negative_regulation of Ednra 21 0.42 12.06 8.19
174 INT7813 Regulation of SRI 25 0.61 6.18 8.13
175 INT77804 Regulation of Ednra 9 0.39 2.71 7.94
176 INT81345 Gene_expression of ADRBK1 21 0.70 2.89 7.9
177 INT54978 Binding of EDNRA 36 0.41 14.97 7.86
178 INT6957 Positive_regulation of OXTR 38 0.70 6.55 7.81
179 INT98178 Localization of Casp3 32 0.65 21.01 7.77
180 INT26643 Negative_regulation of Positive_regulation of Th 12 0.59 1.26 7.74
181 INT81399 Regulation of Vcam1 24 0.46 23.53 7.68
182 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
183 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64
184 INT49104 Positive_regulation of Gene_expression of Vcam1 30 0.69 36.52 7.64
185 INT67170 Gene_expression of Ednra 22 0.65 9.35 7.57
186 INT98856 Negative_regulation of Gene_expression of Adrbk1 5 0.56 0.43 7.29
187 INT50779 Positive_regulation of Gene_expression of Adrbk1 9 0.56 2.79 7.23
188 INT6210 Binding of Nppa 39 0.47 14.35 7.21
189 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
190 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17
191 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03
192 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01
193 INT7624 Positive_regulation of Regulation of Th 7 0.50 2.41 7
194 INT118782 Protein_catabolism of Pax3 7 0.94 0.46 6.95
195 INT102814 Negative_regulation of CASP3 46 0.43 28.54 6.94
196 INT102749 Positive_regulation of Positive_regulation of CASP3 32 0.67 26.07 6.93
197 INT19302 Localization of OXT 31 0.79 3.39 6.92
198 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88
199 INT109266 Negative_regulation of Transcription of Th 9 0.42 2.5 6.85
200 INT167049 Binding of Ednra 3 0.07 3.47 6.84
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