GO:0007519

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Name skeletal muscle tissue development
Categary Process
Go Slim No
Go Link GO:0007519
Unique Molecular Interactions 819
Total Molecular Interactions 1067
Total Single Events 10525
Pain Genes Associated 59

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for skeletal muscle tissue development. They are ordered first by their pain relevance and then by number of times they were reported for skeletal muscle tissue development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7190 Syt17 Positive_regulation of Ctsb 1 0.16 0 3.23
2 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
3 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
4 INT7195 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.10 0 2.25
5 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
6 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
7 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
8 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
9 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56
10 INT158711 Cdk5 Positive_regulation of Phosphorylation of Trh 1 0.02 0 1.46
11 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
12 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
13 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34
14 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32
15 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 0.43 1.48 1.27
16 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
17 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
18 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24
19 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
20 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
21 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
22 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2
23 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
24 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 0.15 1.14 1.13
25 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 0.20 1.14 1.13
26 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
27 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
28 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
29 INT283934 Phax Negative_regulation of Positive_regulation of Mapk14 1 0.03 2.06 1.09
30 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06
31 INT154846 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Trpv1 1 0.23 0.07 1.05
32 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
33 INT352456 Dusp1 Negative_regulation of Mapk14 1 0.03 1.31 1.03
34 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99
35 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95
36 INT145853 Casp1 Positive_regulation of Mapk14 1 0.02 0.68 0.93
37 INT318461 Nnat Positive_regulation of Mapk14 1 0.05 0.97 0.92
38 INT352465 Dusp1 Negative_regulation of Gene_expression of Mapk14 1 0.03 1.09 0.92
39 INT352444 Dusp1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.09 0.91
40 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
41 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
42 INT314207 Ngf Negative_regulation of Phosphorylation of Mapk14 1 0.33 0.4 0.88
43 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
44 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
45 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
46 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
47 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82
48 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
49 INT288201 Mapk14 Positive_regulation of Cish 1 0.03 0.06 0.82
50 INT128590 Mapk14 Regulation of Nav1 1 0.21 0.25 0.82
51 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
52 INT168648 Positive_regulation of Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.35 1.51 0.8
53 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79
54 INT168647 Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.52 1.51 0.79
55 INT128180 Gna12 Regulation of Regulation of RHOA 1 0.00 0 0.78
56 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
57 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
58 INT196575 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1a 1 0.04 0.44 0.77
59 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
60 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
61 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75
62 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74
63 INT134476 Cdk5 Regulation of Map2k1 1 0.69 0.88 0.71
64 INT308167 Binding of Eln and Tnfrsf1b 1 0.01 0.94 0.71
65 INT164783 Positive_regulation of Mapk14 Regulation of Gene_expression of Cx3cr1 1 0.19 0.81 0.68
66 INT155457 Tnfrsf1a Positive_regulation of Mapk14 1 0.20 1.17 0.67
67 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
68 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
69 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
70 INT166299 Binding of Mapk14 and Gpbar1 1 0.13 0.64 0.65
71 INT166302 Negative_regulation of Binding of Mapk14 and Gpbar1 1 0.12 0.64 0.65
72 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
73 INT288202 Negative_regulation of Cd14 Positive_regulation of Positive_regulation of Mapk14 1 0.09 1.08 0.64
74 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
75 INT223155 Binding of Mapk14 and Stat4 1 0.36 0.84 0.63
76 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
77 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
78 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
79 INT36320 PDYN Negative_regulation of Ctsb 1 0.00 0 0.61
80 INT128811 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Casp1 1 0.06 0.35 0.61
81 INT219280 Mapk14 Positive_regulation of Pla2g2a 1 0.33 0.46 0.61
82 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61
83 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61
84 INT219282 Mapk14 Positive_regulation of Pla2g1b 1 0.18 0.46 0.61
85 INT142993 Serpinc1 Positive_regulation of Phosphorylation of RHOA 1 0.05 0.05 0.59
86 INT223158 Mapk3 Regulation of Gene_expression of Mapk14 1 0.48 1.33 0.59
87 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
88 INT314208 Trap1 Positive_regulation of Mapk14 1 0.10 0.66 0.57
89 INT110032 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il12a 1 0.36 0 0.57
90 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
91 INT196585 Mapk14 Regulation of TNF 1 0.02 0.36 0.55
92 INT328744 TNF Regulation of Positive_regulation of Mapk14 1 0.02 0.81 0.55
93 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
94 INT350169 Binding of DMD and MRI1 1 0.11 3.08 0.54
95 INT278227 Binding of MBNL1 and SNRNP70 1 0.01 2.05 0.54
96 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54
97 INT278228 Binding of MBNL1 and NOS3 1 0.05 2.06 0.54
98 INT161250 Trib3 Regulation of Mapk14 1 0.04 0.81 0.54
99 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
100 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
101 INT313376 Cnr1 Positive_regulation of Phosphorylation of Mapk14 1 0.20 0.38 0.5
102 INT104960 Ephb1 Regulation of Positive_regulation of Mapk14 1 0.15 0.42 0.5
103 INT313375 Cnr2 Positive_regulation of Phosphorylation of Mapk14 1 0.18 0.39 0.5
104 INT104961 Mapk14 Regulation of Positive_regulation of Ephb1 1 0.15 0.42 0.5
105 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
106 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
107 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
108 INT110031 Positive_regulation of Adra2c Positive_regulation of Mapk14 1 0.25 0 0.48
109 INT110030 Adra2c Positive_regulation of Mapk14 1 0.25 0 0.48
110 INT110034 Negative_regulation of Adra2c Positive_regulation of Mapk14 1 0.23 0 0.48
111 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
112 INT131504 Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.14 0.2 0.47
113 INT131507 Ngf Positive_regulation of Mapk14 1 0.13 0.2 0.47
114 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46
115 INT254225 Mapk14 Positive_regulation of Mapk8 1 0.02 0.87 0.46
116 INT273235 Binding of Cdk5 and Cdk5r1 1 0.24 6.06 0.46
117 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
118 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46
119 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
120 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46
121 INT168445 Positive_regulation of C2 Positive_regulation of Positive_regulation of Dcn 1 0.14 0.66 0.46
122 INT69637 Binding of CAV1 and Zfp354a 1 0.00 0 0.46
123 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
124 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
125 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
126 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
127 INT313378 Trib3 Regulation of Phosphorylation of Mapk14 1 0.01 0.37 0.44
128 INT264479 Il1a Positive_regulation of Gene_expression of Mapk14 1 0.02 0 0.43
129 INT292634 IL4 Positive_regulation of Gene_expression of FOXP3 1 0.10 0.42 0.43
130 INT124088 Rab38 Negative_regulation of Mapk14 1 0.00 0.89 0.42
131 INT331799 IL8 Negative_regulation of Mapk14 1 0.01 1.6 0.42
132 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
133 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
134 INT335643 CTSB Positive_regulation of PAR4 1 0.01 1.3 0.41
135 INT319313 Socs4 Positive_regulation of Mapk14 1 0.02 0.68 0.41
136 INT95402 Mapk14 Regulation of Positive_regulation of Trib3 1 0.06 0.19 0.41
137 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
138 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
139 INT171990 Binding of DMD and VDR 5 0.05 2.58 0.39
140 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
141 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39
142 INT152241 Mapk14 Positive_regulation of Localization of Nfkb1 1 0.25 0.13 0.39
143 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
144 INT180442 Acot1 Positive_regulation of Rhoa 1 0.08 1.03 0.38
145 INT264482 Il1a Positive_regulation of Phosphorylation of Mapk14 1 0.02 0 0.37
146 INT264481 Il1a Positive_regulation of Mapk14 1 0.02 0 0.37
147 INT337890 Per1 Regulation of Nr2f2 1 0.08 0 0.37
148 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35
149 INT352547 Binding of CFTR and DMD 1 0.01 1.42 0.35
150 INT273234 Negative_regulation of Cdk5 Positive_regulation of Ptprs 1 0.14 1.26 0.34
151 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
152 INT223874 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Ltp 1 0.13 0 0.34
153 INT302830 Mapk14 Regulation of Mapkapk5 1 0.12 0.53 0.33
154 INT191616 Binding of Cbln1 and Nf1 1 0.01 0.2 0.32
155 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32
156 INT288198 Binding of Tlr4 and Mapk14 1 0.01 0.63 0.31
157 INT288203 Binding of Cd14 and Mapk14 1 0.08 0.63 0.31
158 INT191611 Nf1 Regulation of ras 1 0.26 0.18 0.3
159 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3
160 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
161 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
162 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
163 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
164 INT50107 Ei24 Positive_regulation of Localization of CTSB 3 0.00 0.6 0.29
165 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29
166 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29
167 INT167982 Mapk14 Negative_regulation of gr 1 0.02 0.45 0.29
168 INT180570 Binding of HEYL and Positive_regulation of DMD 1 0.00 1.08 0.28
169 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28
170 INT180564 HEYL Regulation of Regulation of DMD 1 0.00 0.88 0.28
171 INT258858 CTSB Positive_regulation of Gene_expression of IL8 1 0.00 0.64 0.28
172 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
173 INT337113 Ppp1r1b Negative_regulation of Phosphorylation of Cdk5 1 0.11 0.28 0.27
174 INT196584 Binding of Mapk14 and NeuN 1 0.02 0.39 0.27
175 INT96788 Binding of SP3 and NR2F2 1 0.24 0.27 0.27
176 INT96789 Binding of SP1 and NR2F2 1 0.24 0.27 0.27
177 INT337884 Ins1 Negative_regulation of Gene_expression of Nr2f2 1 0.11 0.08 0.27
178 INT337896 Ins1 Negative_regulation of Nr2f2 1 0.15 0.1 0.27
179 INT83395 Binding of IL1RN and Tgfb1 1 0.01 0.17 0.26
180 INT257577 CALCA Positive_regulation of DMD 1 0.01 0.57 0.26
181 INT139980 Negative_regulation of CTSB Negative_regulation of Gene_expression of APP 1 0.15 0.7 0.26
182 INT139981 CTSB Negative_regulation of Gene_expression of APP 1 0.11 0.7 0.26
183 INT270216 Mapk14 Positive_regulation of Mknk1 1 0.10 0.5 0.26
184 INT120191 Ccl4 Positive_regulation of Pdlim3 1 0.51 0.24 0.25
185 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
186 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25
187 INT312546 Ros1 Positive_regulation of Positive_regulation of Mapk14 1 0.00 0.87 0.25
188 INT214412 CASQ1 Regulation of JUND 1 0.02 0.46 0.24
189 INT260743 Mapk14 Regulation of Gene_expression of Il10 1 0.04 0.99 0.24
190 INT108841 RXRG Positive_regulation of GDF15 1 0.41 0.58 0.24
191 INT256656 Binding of EP300 and HHIP 1 0.22 0 0.24
192 INT193029 CHRM2 Positive_regulation of RHOA 1 0.01 0.12 0.24
193 INT140376 TGM1 Positive_regulation of Rhoa 1 0.01 0 0.24
194 INT337892 Positive_regulation of Mc4r Positive_regulation of Gene_expression of Nr2f2 1 0.34 0 0.23
195 INT269561 TMPO Positive_regulation of RHOA 1 0.22 0 0.23
196 INT273232 Negative_regulation of Binding of Cdk5 and Cdk5r1 1 0.28 3.16 0.23
197 INT259623 Binding of Eln and Elane 1 0.02 1.38 0.23
198 INT327313 Positive_regulation of Mapk14 Positive_regulation of Phosphorylation of Khsrp 1 0.09 0.24 0.22
199 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
200 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22

Single Events

The table below shows the top 100 pain related interactions that have been reported for skeletal muscle tissue development. They are ordered first by their pain relevance and then by number of times they were reported in skeletal muscle tissue development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61
2 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46
3 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51
4 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79
5 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59
6 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32
7 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42
8 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81
9 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08
10 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
11 INT106272 Positive_regulation of Positive_regulation of Mapk14 39 0.70 32.08 24.71
12 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16
13 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98
14 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68
15 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
16 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25
17 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15
18 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06
19 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52
20 INT104954 Negative_regulation of Positive_regulation of Mapk14 29 0.58 17.71 13.31
21 INT109223 Negative_regulation of Cdk5 14 0.59 3.27 12.73
22 INT110025 Positive_regulation of Positive_regulation of Mapk14 39 0.63 20.67 12.71
23 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
24 INT117113 Regulation of Mapk14 28 0.45 16.71 11.99
25 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
26 INT118906 Regulation of Mapk14 21 0.44 17.95 11.63
27 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
28 INT103923 Negative_regulation of Positive_regulation of Mapk14 23 0.53 13.95 10.64
29 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
30 INT101602 Positive_regulation of Cdk5 15 0.70 4.1 8.96
31 INT3622 Regulation of CTSB 34 0.58 16.08 8.76
32 INT127555 Negative_regulation of Cdk5 59 0.59 50.2 8.45
33 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
34 INT157580 Phosphorylation of Cdk5 4 0.77 0.73 8.33
35 INT159750 Negative_regulation of Gene_expression of Mapk14 15 0.40 10.88 7.81
36 INT7168 Positive_regulation of Ctsb 9 0.70 0.3 7.58
37 INT128695 Regulation of Gene_expression of Mapk14 14 0.44 11.49 7.14
38 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
39 INT128587 Localization of Mapk14 15 0.81 8.41 6.1
40 INT55655 Gene_expression of DCN 17 0.75 7.98 5.98
41 INT127556 Positive_regulation of Cdk5 35 0.70 19.6 5.95
42 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
43 INT101604 Regulation of Cdk5 10 0.61 2.2 5.53
44 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45
45 INT95696 Gene_expression of Dmd 130 0.68 26.02 5.34
46 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
47 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23
48 INT50105 Localization of CTSB 29 0.78 10.98 5.21
49 INT176524 Binding of Mapk14 19 0.43 12.54 5.21
50 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
51 INT126047 Regulation of Phosphorylation of Mapk14 7 0.60 5.05 5.03
52 INT185877 Negative_regulation of Gene_expression of DCN 3 0.33 2.37 4.85
53 INT171472 Binding of Mapk14 10 0.36 6.79 4.83
54 INT7170 Positive_regulation of Positive_regulation of Ctsb 1 0.40 0 4.76
55 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7
56 INT337882 Gene_expression of Nr2f2 1 0.76 3.45 4.6
57 INT68216 Binding of NF1 40 0.48 51.24 4.59
58 INT2213 Regulation of EP300 10 0.54 4.72 4.5
59 INT110024 Negative_regulation of Gene_expression of Mapk14 19 0.42 7.83 4.21
60 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
61 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
62 INT131782 Regulation of Positive_regulation of Mapk14 7 0.43 2.68 4.02
63 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
64 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
65 INT148495 Regulation of Cdk5 6 0.58 5.42 3.95
66 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
67 INT110021 Positive_regulation of Gene_expression of Mapk14 29 0.46 19.06 3.86
68 INT16165 Regulation of DMD 114 0.60 35.13 3.64
69 INT20265 Gene_expression of Ctsb 3 0.47 1.01 3.52
70 INT171998 Binding of DMD 58 0.47 38.13 3.35
71 INT146194 Negative_regulation of Rhoa 21 0.42 11.05 3.22
72 INT128179 Gene_expression of RHOA 7 0.64 2.48 3.01
73 INT146191 Gene_expression of Rhoa 32 0.67 17.63 2.92
74 INT322473 Localization of DCN 1 0.03 0.76 2.9
75 INT155453 Protein_catabolism of Mapk14 6 0.36 4.24 2.85
76 INT8095 Gene_expression of ERBB3 47 0.77 24.85 2.82
77 INT96901 Regulation of Negative_regulation of Mapk14 3 0.45 4.07 2.79
78 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
79 INT53755 Positive_regulation of Dcn 8 0.43 2.91 2.74
80 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
81 INT110980 Gene_expression of CTSB 17 0.45 8.02 2.69
82 INT196733 Gene_expression of Cdk5 25 0.76 18.25 2.64
83 INT138789 Gene_expression of Cdk5 6 0.76 5.19 2.62
84 INT73028 Positive_regulation of Transcription of Ctsb 1 0.55 1.53 2.54
85 INT59135 Positive_regulation of CTSB 15 0.67 7.53 2.53
86 INT140363 Negative_regulation of Rhoa 7 0.58 2.49 2.47
87 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
88 INT61434 Regulation of Nf1 3 0.26 1.39 2.4
89 INT128174 Positive_regulation of Gene_expression of RHOA 7 0.36 1.5 2.36
90 INT37427 Positive_regulation of Gene_expression of Ctsb 2 0.37 1.02 2.33
91 INT148494 Binding of Cdk5 6 0.40 5.97 2.31
92 INT112905 Phosphorylation of Cdk5 15 0.82 2.78 2.3
93 INT146196 Localization of Rhoa 6 0.78 4.68 2.3
94 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29
95 INT64700 Binding of Nf1 14 0.45 15.24 2.29
96 INT7173 Regulation of Positive_regulation of Ctsb 1 0.49 0 2.29
97 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
98 INT51869 Negative_regulation of Dmd 24 0.52 10.4 2.18
99 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17
100 INT157579 Binding of Cdk5 3 0.35 0.47 2.13
101 INT337864 Positive_regulation of Gene_expression of Nr2f2 1 0.68 0.48 2.07
102 INT26123 Regulation of Ep300 6 0.23 1.22 2.03
103 INT57469 Phosphorylation of ZNF238 1 0.24 0.51 2.02
104 INT171514 Binding of EP300 13 0.32 4.32 2.01
105 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98
106 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
107 INT26124 Negative_regulation of Ep300 5 0.37 1.25 1.94
108 INT84510 Positive_regulation of Nf1 8 0.69 9.52 1.93
109 INT68181 Binding of Nf1 6 0.48 8.14 1.88
110 INT126626 Positive_regulation of Rhoa 14 0.69 4.43 1.87
111 INT148492 Positive_regulation of Binding of Cdk5 1 0.47 0.51 1.86
112 INT146193 Negative_regulation of Positive_regulation of Rhoa 3 0.42 3 1.84
113 INT179670 Protein_catabolism of Eln 3 0.19 6.16 1.84
114 INT158710 Negative_regulation of Binding of Cdk5 1 0.40 0 1.84
115 INT85348 Localization of RHOA 12 0.59 4.81 1.83
116 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8
117 INT118907 Negative_regulation of Negative_regulation of Mapk14 2 0.57 2.09 1.77
118 INT152894 Regulation of Positive_regulation of Mapk14 9 0.45 6.01 1.74
119 INT44784 Gene_expression of NPHS1 8 0.64 9.75 1.74
120 INT221426 Positive_regulation of Gene_expression of FOXP3 9 0.48 5.98 1.72
121 INT172622 Localization of EP300 8 0.65 2.56 1.72
122 INT37954 Negative_regulation of Dcn 6 0.41 0.62 1.72
123 INT50106 Positive_regulation of Localization of CTSB 9 0.33 3.15 1.69
124 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
125 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68
126 INT73027 Transcription of Ctsb 1 0.56 1.01 1.68
127 INT168686 Transcription of Mapk14 6 0.52 2.96 1.67
128 INT322472 Negative_regulation of Localization of DCN 1 0.02 0.47 1.64
129 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
130 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
131 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
132 INT146190 Negative_regulation of Localization of Rhoa 4 0.42 1.64 1.5
133 INT52962 Binding of ERBB2 77 0.47 50.03 1.49
134 INT167085 Negative_regulation of ERBB2 67 0.57 44.6 1.48
135 INT57468 Positive_regulation of Phosphorylation of ZNF238 1 0.18 0.35 1.46
136 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
137 INT109222 Positive_regulation of Negative_regulation of Cdk5 2 0.50 0.23 1.39
138 INT158709 Negative_regulation of Phosphorylation of Cdk5 1 0.40 0 1.39
139 INT42335 Binding of CTSB 11 0.34 5.98 1.37
140 INT96838 Negative_regulation of Gene_expression of ERBB2 25 0.57 15.83 1.34
141 INT142992 Phosphorylation of RHOA 3 0.80 0.87 1.28
142 INT128176 Regulation of RHOA 13 0.44 4.35 1.26
143 INT202365 Regulation of Gene_expression of Mapk14 6 0.45 4.89 1.26
144 INT141862 Binding of Cav1 11 0.36 1.32 1.25
145 INT131645 Negative_regulation of Nf1 10 0.58 8.12 1.24
146 INT61993 Gene_expression of NF1 29 0.78 34.47 1.23
147 INT22235 Gene_expression of Eln 11 0.76 5.4 1.23
148 INT111859 Regulation of Rhoa 3 0.61 0.23 1.22
149 INT216103 Positive_regulation of Dmd 15 0.46 5.92 1.21
150 INT70821 Positive_regulation of Ep300 4 0.25 1.47 1.2
151 INT139764 Negative_regulation of CAV1 10 0.58 6.57 1.14
152 INT20317 Localization of Ctsb 3 0.81 0.68 1.12
153 INT59136 Negative_regulation of Positive_regulation of CTSB 3 0.41 2.02 1.11
154 INT126525 Regulation of Negative_regulation of Mapk14 2 0.41 0.81 1.11
155 INT13397 Localization of DMD 21 0.78 7.96 1.08
156 INT231162 Localization of Dmd 6 0.71 2.27 1.07
157 INT136817 Negative_regulation of Positive_regulation of RHOA 8 0.57 0 1.04
158 INT177615 Gene_expression of PAX7 20 0.65 13.5 1.03
159 INT273221 Positive_regulation of Negative_regulation of Cdk5 8 0.49 9.89 1.03
160 INT92988 Protein_catabolism of Eln 6 0.47 5.48 1.03
161 INT167650 Binding of Ep300 1 0.09 0.14 1
162 INT180423 Positive_regulation of Gene_expression of Rhoa 7 0.40 6.22 0.98
163 INT178391 Localization of Mapk14 9 0.68 5.27 0.97
164 INT136613 Negative_regulation of Cav1 2 0.57 2.28 0.96
165 INT145028 Positive_regulation of Localization of Mapk14 2 0.20 0.85 0.96
166 INT337876 Regulation of Nr2f2 1 0.61 0.18 0.96
167 INT161882 Negative_regulation of Gene_expression of NPHS1 2 0.41 6.54 0.95
168 INT192686 Positive_regulation of Positive_regulation of DMD 8 0.41 4.66 0.93
169 INT231494 Regulation of Phosphorylation of Mapk14 2 0.24 2.59 0.93
170 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92
171 INT131824 Negative_regulation of RHOA 10 0.57 2.9 0.92
172 INT203893 Positive_regulation of Gene_expression of Cdk5 2 0.49 7.12 0.92
173 INT337865 Regulation of Gene_expression of Nr2f2 1 0.61 0.31 0.92
174 INT213917 Negative_regulation of Phosphorylation of ERBB2 9 0.54 8.68 0.91
175 INT138788 Positive_regulation of Gene_expression of Cdk5 1 0.49 0.44 0.91
176 INT116314 Gene_expression of Myod1 38 0.70 16.6 0.89
177 INT127452 Positive_regulation of CDK5 5 0.32 1.88 0.87
178 INT141442 Negative_regulation of Phosphorylation of Cav1 1 0.59 0.94 0.87
179 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
180 INT337872 Negative_regulation of Gene_expression of Nr2f2 1 0.42 0.55 0.86
181 INT7175 Negative_regulation of Positive_regulation of Ctsb 1 0.34 0 0.86
182 INT203892 Positive_regulation of Positive_regulation of Cdk5 4 0.49 4.02 0.85
183 INT146195 Positive_regulation of Localization of Rhoa 4 0.45 2.67 0.84
184 INT71649 Localization of ERBB2 23 0.78 13.63 0.83
185 INT44955 Negative_regulation of Eln 8 0.42 3.79 0.83
186 INT221427 Positive_regulation of FOXP3 6 0.45 2.74 0.83
187 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
188 INT62155 Positive_regulation of Gene_expression of DMD 17 0.67 6.17 0.82
189 INT87837 Binding of Dcn 4 0.35 1.28 0.82
190 INT176588 Phosphorylation of ERBB2 27 0.78 16.37 0.81
191 INT219358 Gene_expression of CDK5 9 0.58 5.65 0.81
192 INT138787 Positive_regulation of Positive_regulation of Cdk5 1 0.49 0.38 0.81
193 INT219268 Negative_regulation of Negative_regulation of Mapk14 2 0.38 0.99 0.8
194 INT57466 Positive_regulation of ZNF238 1 0.18 0.17 0.8
195 INT87838 Gene_expression of Dcn 7 0.75 0.74 0.79
196 INT231380 Negative_regulation of Phosphorylation of Rhoa 1 0.13 1.28 0.79
197 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78
198 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77
199 INT82928 Positive_regulation of Eln 7 0.69 3.54 0.77
200 INT150251 Transcription of FOXP3 7 0.61 0.43 0.76
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