GO:0007568

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Name aging
Categary Process
Go Slim Yes
Go Link GO:0007568
Unique Molecular Interactions 4283
Total Molecular Interactions 6238
Total Single Events 67137
Pain Genes Associated 199

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for aging. They are ordered first by their pain relevance and then by number of times they were reported for aging. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
3 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
4 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
5 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
6 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
7 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
8 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
9 INT98346 Negative_regulation of Binding of CPOX and PTGS1 1 0.10 2.91 6.54
10 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
11 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
12 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
13 INT227157 Binding of PEBP1 and Gpm6a 1 0.00 1.28 5.52
14 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
15 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
16 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
17 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
18 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
19 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
20 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49
21 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
22 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
23 INT143270 Binding of Cnr1 and Gprasp1 4 0.54 0.64 4.18
24 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
25 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
26 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97
27 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
28 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
29 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
30 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
31 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
32 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
33 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
34 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
35 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
36 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
37 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
38 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
39 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
40 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
41 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
42 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
43 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
44 INT270949 Binding of Slc6a3 and Cpe 1 0.28 0.25 3.19
45 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
46 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
47 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
48 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
49 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
50 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
51 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
52 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
53 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
54 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
55 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
56 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
57 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
58 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
59 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89
60 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
61 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
62 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
63 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
64 INT130085 Crp Positive_regulation of Gene_expression of Vcam1 1 0.23 4.34 2.84
65 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
66 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
67 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
68 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
69 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
70 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
71 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
72 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
73 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
74 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
75 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64
76 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62
77 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
78 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
79 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
80 INT104219 SCD Positive_regulation of Cnr1 1 0.00 2.67 2.54
81 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
82 INT143271 Binding of Gprasp1 and Positive_regulation of Negative_regulation of Cnr1 1 0.78 0.16 2.53
83 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
84 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
85 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
86 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46
87 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
88 INT143272 Binding of CNR1 and Gprasp1 1 0.01 0.17 2.42
89 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
90 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
91 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37
92 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
93 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
94 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
95 INT108987 Ngf Regulation of Gene_expression of Sit1 1 0.00 1.46 2.32
96 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
97 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
98 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
99 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
100 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
101 INT198958 Cnr1 Positive_regulation of Kcnj9 1 0.00 0.15 2.24
102 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
103 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
104 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
105 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
106 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
107 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
108 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
109 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
110 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 0.69 0.5 2.18
111 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
112 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
113 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
114 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
115 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
116 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
117 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
118 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
119 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
120 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
121 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
122 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
123 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
124 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
125 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
126 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
127 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
128 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
129 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
130 INT274372 Phc1 Negative_regulation of Slc6a3 1 0.06 0.47 1.99
131 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98
132 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
133 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
134 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
135 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
136 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
137 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
138 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
139 INT14991 SFTPA1 Positive_regulation of Localization of MPO 1 0.11 1.65 1.92
140 INT264928 Binding of Cnr1 and Hrh1 1 0.01 1.61 1.92
141 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
142 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
143 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
144 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
145 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
146 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
147 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85
148 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
149 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
150 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
151 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
152 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8
153 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
154 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
155 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
156 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
157 INT336556 SLC6A3 Positive_regulation of Gene_expression of GOPC 1 0.08 1.87 1.76
158 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76
159 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
160 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
161 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
162 INT37840 Binding of Cyp27b1 and Oprd1 1 0.01 0 1.73
163 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
164 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
165 INT264922 Binding of Cnr1 and Mors1 1 0.14 0.1 1.71
166 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
167 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
168 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
169 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
170 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
171 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
172 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
173 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
174 INT80199 Ngf Regulation of Transcription of Rab38 1 0.01 1.48 1.68
175 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
176 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
177 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
178 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
179 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
180 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
181 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
182 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
183 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
184 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
185 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
186 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
187 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
188 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
189 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
190 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
191 INT73116 TYMS Negative_regulation of DNMT3B 1 0.24 0 1.6
192 INT73115 TYMS Negative_regulation of Positive_regulation of DNMT3B 1 0.24 0 1.6
193 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
194 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
195 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
196 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
197 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
198 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56
199 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
200 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55

Single Events

The table below shows the top 100 pain related interactions that have been reported for aging. They are ordered first by their pain relevance and then by number of times they were reported in aging. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
3 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
4 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
5 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
6 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
7 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
8 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
9 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
10 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
11 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26
12 INT2649 Regulation of Calca 433 0.62 146.05 330.95
13 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56
14 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
15 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
16 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
17 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238
18 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
19 INT626 Localization of CALCA 289 0.81 125.39 221.15
20 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
21 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
22 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6
23 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
24 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
25 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
26 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
27 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
28 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
29 INT2541 Binding of Calca 200 0.48 67.14 134.62
30 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
31 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34
32 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
33 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58
34 INT12082 Localization of IL6 365 0.81 241.78 105.78
35 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
36 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
37 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
38 INT5587 Regulation of Fos 191 0.62 40.81 99.7
39 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
40 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
41 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71
42 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49
43 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7
44 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
45 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08
46 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
47 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
48 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47
49 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19
50 INT12001 Regulation of Ngf 97 0.62 54.64 76.25
51 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
52 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
53 INT3034 Localization of Ngf 126 0.81 50.81 72.84
54 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
55 INT6849 Localization of IL1B 229 0.81 112.56 69.63
56 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
57 INT19511 Localization of Il6 212 0.81 118.17 67.67
58 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33
59 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84
60 INT10706 Regulation of Il6 150 0.62 93.23 62.34
61 INT6761 Binding of CALCA 100 0.48 26.71 62.05
62 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
63 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5
64 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
65 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
66 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
67 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29
68 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
69 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
70 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
71 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
72 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
73 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
74 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
75 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
76 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
77 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
78 INT4891 Transcription of Calca 81 0.72 35.27 53.75
79 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
80 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
81 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
82 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04
83 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
84 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75
85 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
86 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51
87 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
88 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05
89 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
90 INT9210 Regulation of IL6 166 0.62 125.61 49.95
91 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
92 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
93 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
94 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
95 INT63383 Binding of Cnr1 77 0.48 22.28 44.61
96 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41
97 INT19078 Binding of Ngf 78 0.48 31.03 44.33
98 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01
99 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
100 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68
101 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
102 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
103 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
104 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
105 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
106 INT16194 Binding of CNR1 82 0.48 20.75 39.59
107 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57
108 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
109 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
110 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78
111 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54
112 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
113 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
114 INT12608 Regulation of CNR1 62 0.60 24.36 36.02
115 INT6484 Binding of IL1B 122 0.47 75.84 35.07
116 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52
117 INT50308 Binding of Cnr1 61 0.48 14.41 33.52
118 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
119 INT65698 Localization of CCL2 118 0.81 77.54 32.69
120 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
121 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4
122 INT6053 Transcription of Fos 107 0.72 20.97 31.88
123 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
124 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
125 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
126 INT9347 Localization of Il1b 58 0.81 26.13 31.53
127 INT47764 Binding of Jun 106 0.48 22.62 31.39
128 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16
129 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
130 INT6058 Localization of Fos 73 0.81 16.7 30.84
131 INT1158 Regulation of Agt 106 0.61 29.4 30.29
132 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
133 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
134 INT86437 Binding of IL6 154 0.48 121.22 29.3
135 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18
136 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95
137 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
138 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
139 INT116737 Localization of Mif 63 0.81 52.97 28.11
140 INT82882 Localization of Ccl2 61 0.80 41.96 28
141 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
142 INT111359 Localization of Cnr1 55 0.81 11.25 27.41
143 INT75418 Negative_regulation of Cnr1 41 0.59 14.65 27.28
144 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26
145 INT5923 Negative_regulation of Rtn4 50 0.36 24.19 27.2
146 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
147 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9
148 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42
149 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
150 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95
151 INT80791 Gene_expression of Slc6a3 113 0.78 11.89 25.76
152 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
153 INT61953 Transcription of Nos2 101 0.72 46.64 25.49
154 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
155 INT74688 Regulation of Nos1 55 0.62 22.16 25.3
156 INT74377 Regulation of Cnr1 38 0.59 16.93 24.77
157 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
158 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
159 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
160 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
161 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01
162 INT37889 Gene_expression of P2ry2 75 0.65 26.01 23.8
163 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
164 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
165 INT48081 Localization of Il1b 46 0.80 21.59 22.4
166 INT21503 Binding of Ptgs1 45 0.48 15.6 22.29
167 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
168 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
169 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05
170 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
171 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
172 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
173 INT74059 Positive_regulation of Gene_expression of Nos1 55 0.70 11.5 21.39
174 INT5586 Binding of Fos 47 0.48 12.7 21.33
175 INT61825 Negative_regulation of Slc6a3 47 0.59 6.52 21.27
176 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75
177 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
178 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61
179 INT78901 Localization of CCL5 67 0.78 40.79 20.59
180 INT51474 Binding of Il6 55 0.48 44.99 20.52
181 INT45840 Positive_regulation of Gene_expression of Ptgs1 35 0.50 16.07 20.49
182 INT8765 Positive_regulation of Cyp3a23/3a1 63 0.67 22.28 20.39
183 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
184 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
185 INT10442 Negative_regulation of CNR1 47 0.59 20.88 20.2
186 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03
187 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86
188 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85
189 INT64261 Negative_regulation of Positive_regulation of Ngf 21 0.59 16.28 19.78
190 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59
191 INT79955 Localization of Cnr1 26 0.81 8.44 19.06
192 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01
193 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
194 INT56239 Positive_regulation of Rtn4 20 0.26 14.05 18.8
195 INT18672 Gene_expression of Ncam1 54 0.78 36.64 18.79
196 INT7000 Positive_regulation of Htr2a 42 0.67 9.48 18.7
197 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
198 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
199 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
200 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
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